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Integrin laminin receptors and breast carcinoma progression
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
Structure and function of a vimentin-associated matrix adhesion in endothelial cells
MOLECULAR BIOLOGY OF THE CELL
Towards a mechanistic understanding of tumor invasion - lessons from the alpha 6 beta 4 integrin
SEMINARS IN CANCER BIOLOGY
Regulation of the cytoskeleton by Rho-family GTPases: implications for tumour cell invasion
SEMINARS IN CANCER BIOLOGY
Retinoic acid and extracellular matrix inhibition of matrix metalloproteinase 9 expression is mediated by the mitogen activated protein kinase pathway
INTERNATIONAL JOURNAL OF ONCOLOGY
The alpha 6 beta 4 integrin and epithelial cell migration
CURRENT OPINION IN CELL BIOLOGY
Altered expression of collagen XVII in ameloblastomas, and basal cell carcinomas
JOURNAL OF ORAL PATHOLOGY & MEDICINE
Laminin-5-mediated gene expression in human prostate carcinoma cells
MOLECULAR CARCINOGENESIS
CD104
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
beta 3 tyrosine phosphorylation in alpha IIb beta 3 (platelet membrane GP IIb-IIIa) outside-in integrin signaling
THROMBOSIS AND HAEMOSTASIS
Metastatic growth of squamous cell carcinomas is correlated with upregulation and redistribution of hemidesmosomal components
CELL AND TISSUE RESEARCH
Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha 6 beta 4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion
MOLECULAR AND CELLULAR BIOLOGY
Unique expression pattern of the alpha 6 beta 4 integrin and laminin-5 in human prostate carcinoma
PROSTATE
Cyclic AMP specific phosphodiesterase activity and colon cancer cell motility
CLINICAL & EXPERIMENTAL METASTASIS
Biological and clinical relevance of Laminin-5 in cancer
CLINICAL & EXPERIMENTAL METASTASIS
True epithelial hyperplasia in the thymus of early-onset myasthenia gravispatients: implications for immunopathogenesis
JOURNAL OF NEUROIMMUNOLOGY
A signaling adapter function for alpha 6 beta 4 integrin in the control ofHGF-dependent invasive growth
CELL
Human hepatocellular carcinoma (HCC) cells require both alpha 3 beta 1 integrin and matrix metalloproteinases activity for migration and invasion
LABORATORY INVESTIGATION
Human papillomavirus type 6b virus-like particles are able to activate theRas-MAP kinase pathway and induce cell proliferation
JOURNAL OF VIROLOGY
The interaction of plectin with actin: evidence for cross-linking of actinfilaments by dimerization of the actin-binding domain of plectin
JOURNAL OF CELL SCIENCE
EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6 beta 4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion
JOURNAL OF CELL BIOLOGY
Inhibitory role of alpha 6 beta 4-associated erbB-2 and phosphoinositide 3-kinase in keratinocyte haptotactic migration dependent on alpha 3 beta 1 integrin
JOURNAL OF CELL BIOLOGY
Ligation of integrin alpha(3)beta(1) by laminin 5 at the wound edge activates Rho-dependent adhesion of leading keratinocytes on collagen
JOURNAL OF BIOLOGICAL CHEMISTRY
Gene correction of integrin beta(4)-dependent pyloric atresia-functional epidermolysis bullosa keratinocytes establishes a role for beta(4) tyrosines1422 and 1440 in hemidesmosome assembly.
JOURNAL OF BIOLOGICAL CHEMISTRY
The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN - Molecular cloning of multiple alternative splice variants of ERBIN and analysis of their tissue expression
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification of a novel structural variant of the alpha(6) integrin
JOURNAL OF BIOLOGICAL CHEMISTRY
The breast cancer beta(4) integrin and endothelial human CLCA2 mediate lung metastasis
JOURNAL OF BIOLOGICAL CHEMISTRY
Tyrosine phosphorylation of the beta(4) integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes
JOURNAL OF BIOLOGICAL CHEMISTRY
The expression of laminin-5 and ultrastructure of the interface between basal cells and underlying stroma in the keratoconus cornea
JAPANESE JOURNAL OF OPHTHALMOLOGY
Overexpression of laminin alpha 1 chain in colonic cancer cells induces anincrease in tumor growth
INTERNATIONAL JOURNAL OF CANCER
Laminin-10 mediates basal and EGF-stimulated motility of human colon carcinoma cells via alpha(3)beta(1) and alpha(6)beta(4) integrins
EXPERIMENTAL CELL RESEARCH
Phosphatidylinositol 3-kinases in tumor progression
EUROPEAN JOURNAL OF BIOCHEMISTRY
Synthetic peptides inhibit adhesion of human tumor cells to extracellular matrix proteins
CANCER RESEARCH
Influence of beta 1 integrins on epidermal squamous cell carcinoma formation in a transgenic mouse model: alpha 3 beta 1, but not alpha 2 beta l, suppresses malignant conversion
CANCER RESEARCH
Protein kinase C delta-mediated phosphorylation of alpha 6 beta 4 is associated with reduced integrin localization to the hemidesmosome and decreasedkeratinocyte attachment
CANCER RESEARCH
alpha 6 beta 4 integrin abnormalities in junctional epidermolysis bullosa with pyloric atresia
BRITISH JOURNAL OF DERMATOLOGY
Genomic organization, amplification, fine mapping, and intragenic polymorphisms of the human hemidesmosomal tetraspanin CD151 gene
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Epidermal growth factor receptor signaling and the invasive phenotype of ovarian carcinoma cells
JOURNAL OF THE NATIONAL CANCER INSTITUTE
RAC1/P38 MAPK signaling pathway controls beta 1 integrin-induced interleukin-8 production in human natural killer cells
IMMUNITY
Integrins as mediators of epithelial cell-matrix interactions in the humansmall intestinal mucosa
MICROSCOPY RESEARCH AND TECHNIQUE
Integrin alpha 5/beta 1 mediates fibronectin-dependent epithelial cell proliferation through epidermal growth factor receptor activation
MOLECULAR BIOLOGY OF THE CELL
The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome
MOLECULAR BIOLOGY OF THE CELL
New aspects of integrin signaling in cancer
SEMINARS IN CANCER BIOLOGY
Deposition of laminin 5 in epidermal wounds regulates integrin signaling and adhesion
CURRENT OPINION IN CELL BIOLOGY
Intracellular signalling cascades activated by the EGF receptor and/or by integrins, with potential relevance for branching morphogenesis of the fetal mouse submandibular gland
EUROPEAN JOURNAL OF MORPHOLOGY
Molecular biological diagnosis of bladder carcinoma
UROLOGE A
Tyrosine phosphorylation: a critical component in the formation of hemidesmosomes
CELL AND TISSUE RESEARCH
Effects of sulfur mustard on the basal cell adhesion complex
JOURNAL OF APPLIED TOXICOLOGY
Effects of sulfur mustard on the basal cell adhesion complex
JOURNAL OF APPLIED TOXICOLOGY
Prenatal diagnosis of pyloric atresia-junctional epidermolysis bullosa syndrome in a fetus not known to be at risk
PRENATAL DIAGNOSIS
The tetraspanin CD9 associates with the integrin alpha 6 beta 4 in cultured human epidermal keratinocytes and is involved in cell motility
EUROPEAN JOURNAL OF CELL BIOLOGY
Disruption of the basement membrane after corneal debridement
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Distinct structural forms of type I collagen modulate cell cycle regulatory proteins in mesangial cells
KIDNEY INTERNATIONAL
Human bronchial epithelial cells secrete laminin 5, express hemidesmosomalproteins, and assemble hemidesmosomes
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
Formation of hemidesmosome-like structures in the absence of ligand binding by the alpha 6 beta 4 integrin requires binding of HD1/plectin to the cytoplasmic domain of the beta 4 integrin subunit
JOURNAL OF CELL SCIENCE
alpha 3 beta 1 and alpha 6 beta 4 integrin receptors for laminin-5 are notessential for epidermal morphogenesis and homeostasis during skin development
JOURNAL OF CELL SCIENCE
The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha 6 beta 4 and may regulate the spatial organization of hemidesmosomes
JOURNAL OF CELL BIOLOGY
Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5
JOURNAL OF CELL BIOLOGY
Expression of cell adhesion complexes in epithelial cells seeded on biomaterial surfaces
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
Identification of Shc as the primary protein binding to the tyrosine-phosphorylated beta(3) subunit of alpha(IIb)beta(3) during outside-in integrin platelet signaling
JOURNAL OF BIOLOGICAL CHEMISTRY
Deposition of laminin 5 by keratinocytes regulates integrin adhesion and signaling
JOURNAL OF BIOLOGICAL CHEMISTRY
Cooperative signaling between alpha(6)beta(4) integrin and ErbB-2 receptoris required to promote phosphatidylinositol 3-kinase-dependent invasion
JOURNAL OF BIOLOGICAL CHEMISTRY
Anti-beta 4 integrin antibodies enhance migratory and invasive abilities of human colon adenocarcinoma cells and their MMP-2 expression
INTERNATIONAL JOURNAL OF CANCER
Integrin alpha 6 beta 4 as a suppressor and a predictive marker for peritoneal dissemination in human gastric cancer
GASTROENTEROLOGY
Intestinal restitution: Progression of actin cytoskeleton rearrangements and integrin function in a model of epithelial wound healing
AMERICAN JOURNAL OF PATHOLOGY
Division of labor among the alpha 6 beta 4 integrin, beta 1 integrins, andan E3 laminin receptor to signal morphogenesis and beta-casein expression in mammary epithelial cells
MOLECULAR BIOLOGY OF THE CELL
A cell signal pathway involving laminin-5, alpha 3 beta 1 integrin, and mitogen-activated protein kinase can regulate epithelial cell proliferation
MOLECULAR BIOLOGY OF THE CELL
Reduced substratum adhesion and decreased expressions of beta 1 and beta 4integrins in human breast cancer cells with a property of anchorage-independent growth
INTERNATIONAL JOURNAL OF ONCOLOGY
Localization of laminin-5, HD1/plectin, and BP230 in the submandibular glands of developing and adult mice
HISTOCHEMISTRY AND CELL BIOLOGY
Biology and function of hemidesmosomes
MATRIX BIOLOGY
Laminin receptor alpha 6 beta 4 integrin is highly expressed in ENU-induced glioma in rat
GLIA
Human p120(ctn) catenin: Tissue-specific expression of isoforms and molecular interactions with BP180 type XVII collagen
JOURNAL OF CELLULAR BIOCHEMISTRY
Molecular genetics of the cutaneous basement membrane zone: clinical implications of basic research on epidermolysis bullosa
MOLECULAR MEDICINE: NOVEL FINDINGS OF GENE DIAGNOSIS, REGULATION OF GENE EXPRESSION, AND GENE THERAPY
Defects of basement membrane and hemidesmosome structure correlate with malignant phenotype and stromal interactions in HaCaT-Ras xenografts
DIFFERENTIATION
Crystal structure of a tandem pair of fibronectin type III domains from the cytoplasmic tail of integrin alpha 6 beta 4
EMBO JOURNAL
The role of antibody to human beta 4 integrin in conjunctival basement membrane separation: Possible in vitro model for ocular cicatricial pemphigoid
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Regulation of mesangial cell proliferation
KIDNEY INTERNATIONAL
Expression of the alpha 6 integrin confers papillomavirus binding upon receptor-negative B-cells
VIROLOGY
Monoclonal antibodies against integrin subunits alpha 6 and beta 1 inhibitmigration of gingival epithelium in organ culture
JOURNAL OF PERIODONTOLOGY
Structure sand function of hemidesmosomes: More than simple adhesion complexes
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Partial rescue of epithelial phenotype in integrin beta 4 null mice by a keratin-5 promoter driven human integrin beta 4 transgene
JOURNAL OF CELL SCIENCE
Binding of integrin alpha 6 beta 4 to plectin prevents plectin associationwith F-actin but does not interfere with intermediate filament binding
JOURNAL OF CELL BIOLOGY
Integrin-mediated activation of focal adhesion kinase is required for signaling to jun NH2-terminal kinase and progression through the G1 phase of the cell cycle
JOURNAL OF CELL BIOLOGY
Targeted disruption of the LAMA3 gene in mice reveals abnormalities in survival and late stage differentiation of epithelial cells
JOURNAL OF CELL BIOLOGY
The beta 4 integrin interactor p27(BBP/eIF6) is an essential nuclear matrix protein involved in 60S ribosomal subunit assembly
JOURNAL OF CELL BIOLOGY
Laminin 5 in the human thymus: Control of T cell proliferation via alpha(6)beta(4) integrins
JOURNAL OF CELL BIOLOGY
Expression of functionally distinct variants of the beta(4)A integrin subunit in relation to the differentiation state in human intestinal cell
JOURNAL OF BIOLOGICAL CHEMISTRY
Activated Rac1 selectively up-regulates the expression of integrin alpha 6beta 4 and induces cell adhesion and membrane ruffles of nonadherent coloncancer Colo201 cells
EXPERIMENTAL CELL RESEARCH
Regulation of the type II hemidesmosomal plaque assembly in intestinal epithelial cells
EXPERIMENTAL CELL RESEARCH
The keratinocyte-derived cytokine IL-7 increases adhesion of the epidermalT cell subset to the skin basement membrane protein laminin-5
EUROPEAN JOURNAL OF IMMUNOLOGY
The beta 4 integrin subunit rescues A431 cells from apoptosis through a PI3K/Akt kinase signaling pathway
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Immobilized gallium(III) affinity chromatography of phosphopeptides
ANALYTICAL CHEMISTRY
Expression of matrix metalloprotease-2-cleaved laminin-5 in breast remodeling stimulated by sex steroids
AMERICAN JOURNAL OF PATHOLOGY
PROGNOSTIC VALUE OF ALPHA-6-BETA-4 INTEGRIN EXPRESSION IN BREAST CARCINOMAS IS AFFECTED BY LAMININ PRODUCTION FROM TUMOR-CELLS
Clinical cancer research
PROGNOSTIC VALUE OF ALPHA-6-BETA-4 INTEGRIN EXPRESSION IN BREAST CARCINOMAS IS AFFECTED BY LAMININ PRODUCTION FROM TUMOR-CELLS
Clinical cancer research
HEMIDESMOSOMES AND THEIR UNIQUE TRANSMEMBRANE PROTEIN BP180
Microscopy research and technique
EXPRESSION AND LOCALIZATION OF LAMININ-5 SUBUNITS DURING MOUSE TOOTH DEVELOPMENT
Developmental dynamics
CORRECTIVE TRANSDUCTION OF HUMAN EPIDERMAL STEM-CELLS IN LAMININ-5-DEPENDENT JUNCTIONAL EPIDERMOLYSIS-BULLOSA
Human gene therapy
VEGF VPF OVEREXPRESSION IN SKIN OF TRANSGENIC MICE INDUCES ANGIOGENESIS, VASCULAR HYPERPERMEABILITY AND ACCELERATED TUMOR-DEVELOPMENT/
Oncogene
INTEGRINS IN THYROID-TISSUE - UP-REGULATION OF ALPHA-2-BETA-1 IN ANAPLASTIC THYROID-CARCINOMA
European journal of endocrinology