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La ricerca find articoli where soggetti phrase all words 'AIRWAYS' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 2609 riferimenti
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    1. Thio, BJ; Slingerland, GLM; Nagelkerke, AF; Roord, JJ; Mulder, PGH; Dankert-Roelse, JE
      Effects of single-dose fluticasone on exercise-induced asthma in asthmaticchildren: A pilot study

      PEDIATRIC PULMONOLOGY
    2. Campanella, SG; Asher, MI
      Current controversies: Sinus disease and the lower airways

      PEDIATRIC PULMONOLOGY
    3. Davis, S; Jones, M; Kisling, J; Howard, J; Tepper, RS
      Comparison of normal infants and infants with cystic fibrosis using forcedexpiratory flows breathing air and heliox

      PEDIATRIC PULMONOLOGY
    4. Borowitz, D; Armstrong, D; Cerny, F
      Relief of central airways obstruction following spinal release in a patient with idiopathic scoliosis

      PEDIATRIC PULMONOLOGY
    5. Canning, BJ; Reynolds, SM; Mazzone, SB
      Multiple mechanisms of reflex bronchospasm in guinea pigs

      JOURNAL OF APPLIED PHYSIOLOGY
    6. Perillo, IB; Hyde, RW; Olszowka, AJ; Pietropaoli, AP; Frasier, LM; Torres, A; Perkins, PT; Forster, RE; Utell, MJ; Frampton, MW
      Chemiluminescent measurements of nitric oxide pulmonary diffusing capacityand alveolar production in humans

      JOURNAL OF APPLIED PHYSIOLOGY
    7. Serikov, VB; Fleming, NW
      Pulmonary and bronchial circulations: contributions to heat and water exchange in isolated lungs

      JOURNAL OF APPLIED PHYSIOLOGY
    8. Shin, HW; Rose-Gottron, CM; Perez, F; Cooper, DM; Wilson, AF; George, SC
      Flow-independent nitric oxide exchange parameters in healthy adults

      JOURNAL OF APPLIED PHYSIOLOGY
    9. Feroah, TR; Forster, HV; Pan, L; Schlick, NE; Martino, P; Rice, T
      Negative pressure effects on mechanically opposing pharyngeal muscles in awake and sleeping goats

      JOURNAL OF APPLIED PHYSIOLOGY
    10. Fisher, KV; Telser, A; Phillips, JE; Yeates, DB
      Regulation of vocal fold transepithelial water fluxes

      JOURNAL OF APPLIED PHYSIOLOGY
    11. Seow, CY; Fredberg, JJ
      Signal transduction in smooth muscle - Historical perspective on airway smooth muscle: the saga of a frustrated cell

      JOURNAL OF APPLIED PHYSIOLOGY
    12. Holzhauser, U; Lambert, RK
      Analysis of tracheal mechanics and applications

      JOURNAL OF APPLIED PHYSIOLOGY
    13. Sylvester, JT; Permutt, S
      Exhaled NO: first, hold your breath

      JOURNAL OF APPLIED PHYSIOLOGY
    14. Tsoukias, NM; Shin, HW; Wilson, AF; George, SC
      A single-breath technique with variable flow rate to characterize nitric oxide exchange dynamics in the lungs

      JOURNAL OF APPLIED PHYSIOLOGY
    15. Marantz, MJ; Vincent, SG; Fisher, JT
      Role of vagal C-fiber afferents in the bronchomotor response to lactic acid in the newborn dog

      JOURNAL OF APPLIED PHYSIOLOGY
    16. Shardonofsky, FR; Officer, TM; Boriek, AM; Rodarte, JR
      Effects of smooth muscle activation on axial mechanical properties of excised canine bronchi

      JOURNAL OF APPLIED PHYSIOLOGY
    17. Chen, BT; Yeates, DB
      Ion transport and regulation of respiratory tract fluid output in dogs

      JOURNAL OF APPLIED PHYSIOLOGY
    18. Stitt, JT; DuBois, AB
      The lung diffusing capacity for nitric oxide in rats is increased during endotoxemia

      JOURNAL OF APPLIED PHYSIOLOGY
    19. Caye-Thomasen, P; Hermansson, A; Tos, M; Prellner, K
      Goblet cell density in acute otitis media caused by Moraxella catarrhalis

      OTOLOGY & NEUROTOLOGY
    20. Bakke, B; Stewart, P; Ulvestad, B; Eduard, W
      Dust and gas exposure in tunnel construction work

      AIHAJ
    21. Young, SH; Robinson, VA; Barger, M; Porter, DW; Frazer, DG; Castranova, V
      Acute inflammation and recovery in rats after intratracheal instillation of a 1 -> 3-beta-glucan (zymosan A)

      JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A
    22. Grotberg, JB
      Respiratory fluid mechanics and transport processes

      ANNUAL REVIEW OF BIOMEDICAL ENGINEERING
    23. Passalacqua, G; Canonica, GW
      Impact of rhinitis on airway inflammation: biological and therapeutic implications

      RESPIRATORY RESEARCH
    24. Tulic, MK; Christodoulopoulos, P; Hamid, Q
      Small airway inflammation in asthma

      RESPIRATORY RESEARCH
    25. Undem, BJ; Carr, MJ
      Pharmacology of airway afferent nerve activity

      RESPIRATORY RESEARCH
    26. Nadel, JA
      Role of epidermal growth factor receptor activation in regulating mucin synthesis

      RESPIRATORY RESEARCH
    27. Lomas, DA; Silverman, EK
      The genetics of chronic obstructive pulmonary disease

      RESPIRATORY RESEARCH
    28. Walsh, DA; Pearson, CI
      Angiogenesis in the pathogenesis of inflammatory joint and lung diseases

      ARTHRITIS RESEARCH
    29. Kusser, B; Braun, A; Praun, M; Illi, S; von Mutius, E; Roscher, AA
      Polymorphisms in the bradykinin B2 receptor gene and childhood asthma

      BIOLOGICAL CHEMISTRY
    30. Frey, U
      Why are infants prone to wheeze? Physiological aspects of wheezing disorders in infants

      SWISS MEDICAL WEEKLY
    31. Jeffery, PK
      Immunopathology: Comparison of COPD and asthma

      NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
    32. Disse, B; Witek, TJ
      Anticholinergics: Tiotropium

      NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
    33. Out, TA; de Pater-Huijsen, FL; Jansen, HM; Corrigan, CJ
      CD8 T cells: Potential therapeutic targets?

      NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
    34. Bryan, S; Kobayashi, M; Sur, S
      Interleukin-12, interleukin-18 and interferon-gamma

      NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
    35. Sinigaglia, F; Fabbri, LM; D'Ambrosio, D
      Chemokine receptors on Th1 and Th2 cells

      NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
    36. Duhamel, G; Choquet, P; Grillon, E; Leviel, JL; Ziegler, A; Constantinesco, A
      Rat brain perfusion measurements with hyperpolarized Xe-129-NMR: study of biological fluids for the delivery of Xe-129.

      COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE II FASCICULE C-CHIMIE
    37. Malcolm, E; Arruda, E; Hayden, FG; Kaiser, L
      Clinical features of patients with acute respiratory illness and rhinovirus in their bronchoalveolar lavages

      JOURNAL OF CLINICAL VIROLOGY
    38. Banerjee, R; Bellare, JR; Puniyani, RR
      Effect of phospholipid mixtures and surfactant formulations on rheology ofpolymeric gels, simulating mucus, at shear rates experienced in the tracheobronchial tree

      BIOCHEMICAL ENGINEERING JOURNAL
    39. Heindl, S; Dodt, C; Krahwinkel, M; Hasenfuss, G; Andreas, S
      Short term effect of continuous positive airway pressure on muscle sympathetic nerve activity in patients with chronic heart failure

      HEART
    40. Giembycz, MA
      Cilomilast: a second generation phosphodiesterase 4 inhibitor for asthma and chronic obstructive pulmonary disease

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    41. Barnes, PJ
      Tiotropium bromide

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    42. Eduard, W; Douwes, J; Mehl, R; Heederik, D; Melbostad, E
      Short term exposure to airborne microbial agents during farm work: exposure-response relations with eye and respiratory symptoms

      OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
    43. Ulvestad, B; Bakke, B; Eduard, W; Kongerud, J; Lund, MB
      Cumulative exposure to dust causes accelerated decline in lung function intunnel workers

      OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
    44. Costantino, ML; Fiore, GB
      A model of neonatal tidal liquid ventilation mechanics

      MEDICAL ENGINEERING & PHYSICS
    45. Hancox, RJ; Taylor, DR
      Long-acting beta-agonist treatment in patients with persistent asthma already receiving inhaled corticosteroids

      BIODRUGS
    46. Dykewicz, MS
      Occupational asthma: A practical approach

      ALLERGY AND ASTHMA PROCEEDINGS
    47. Jallat-Daloz, I; Cognard, JL; Badet, JM; Regnard, J
      Neural-epithelial cell interplay: In vitro evidence that vagal mediators increase PGE(2) production by human nasal epithelial cells

      ALLERGY AND ASTHMA PROCEEDINGS
    48. Tobin, MJ
      Asthma, airway biology, and allergic rhinitis in AJRCCM 2000

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    49. Seemungal, T; Harper-Owen, R; Bhowmik, A; Moric, I; Sanderson, G; Message, S; MacCallum, P; Meade, TW; Jeffries, DJ; Johnston, SL; Wedzicha, JA
      Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    50. McCloskey, SC; Patel, BD; Hinchliffe, SJ; Reid, ED; Wareham, NJ; Lomas, DA
      Siblings of patients with severe chronic obstructive pulmonary disease have a significant risk of airflow obstruction

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    51. Sagel, SD; Kapsner, R; Osberg, I; Sontag, MK; Accurso, FJ
      Airway inflammation in children with cystic fibrosis and healthy children assessed by sputum induction

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    52. Maestrelli, P; El Messlemani, AH; De Fina, O; Nowicki, Y; Saetta, M; Mapp, C; Fabbri, LM
      Increased expression of heme oxygenase (HO)-1 in alveolar spaces and HO-2 in alveolar walls of smokers

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    53. Ghio, AJ; Gilbey, JG; Roggli, VL; Richards, JH; McGee, JK; Carson, JL; Devlin, RB; Cascio, WE
      Diffuse alveolar damage after exposure to an oil fly ash

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    54. Cross, CE; van der Vliet, A; Eiserich, JP
      Peroxidases wheezing their way into asthma

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    55. Kepley, CL; McFeeley, PJ; Oliver, JM; Lipscomb, MF
      Immunohistochemical detection of human basophils in postmortem cases of fatal asthma

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    56. Chen, Y; Zhao, YH; Wu, R
      In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    57. Dahl, R; Greefhorst, LAPM; Nowak, D; Nonikov, V; Byrne, AM; Thomson, MH; Till, D; Della Cioppa, G
      Inhaled formoterol dry powder versus ipratropium bromide in chronic obstructive pulmonary disease

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    58. Baldi, S; Miniati, M; Bellina, CR; Battolla, L; Catapano, G; Begliomini, E; Giustini, D; Giuntini, C
      Relationship between extent of pulmonary emphysema by high-resolution computed tomography and lung elastic recoil in patients with chronic obstructive pulmonary disease

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    59. Suto, A; Nakajima, H; Kagami, SI; Suzuki, K; Saito, Y; Iwamoto, I
      Role of CD4+ CD25(+) regulatory T cells in T helper 2 cell-mediated allergic inflammation in the airways

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    60. Coultas, DB; Mapel, D; Gagnon, R; Lydick, E
      The health impact of undiagnosed airflow obstruction in a national sample of United States adults

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    61. Retamales, I; Elliott, WM; Meshi, B; Coxson, HO; Pare, PD; Sciurba, FC; Rogers, RM; Hayashi, S; Hogg, JC
      Amplification of inflammation in emphysema and its association with latentadenoviral infection

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    62. Bennett, WD; Zeman, KL; Foy, C; Shaffer, CL; Johnson, FL; Regnis, JA; Sannuti, A; Johnson, J
      Effect of aerosolized uridine 5 '-triphosphate on mucociliary clearance inmild chronic bronchitis

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    63. Costabel, U
      Bronchial eosinophilia in exacerbation of bronchitis - An allergic profileof inflammation?

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    64. Kraft, M; Pak, J; Martin, RJ; Kaminsky, D; Irvin, CG
      Distal lung dysfunction at night in nocturnal asthma

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    65. Lehtimaki, L; Kankaanranta, H; Saarelainen, S; Hahtola, P; Jarvenpaa, R; Koivula, T; Turjanmaa, V; Moilanen, E
      Extended exhaled NO measurement differentiates between alveolar and bronchial inflammation

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    66. Kobayashi, T; Gabazza, EC; Shimizu, S; Yasui, H; Yuda, H; Hataji, O; Maruyama, K; Yamauchi, T; Suzuki, K; Adachi, Y; Taguchi, O
      Long-term inhalation of high-dose nitric oxide increases intraalveolar activation of coagulation system in mice

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    67. Saetta, M; Turato, G; Maestrelli, P; Mapp, CE; Fabbri, LM
      Cellular and structural bases of chronic obstructive pulmonary disease

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    68. On, LS; Boonyoncsunchai, P; Webb, S; Davies, L; Calverley, PMA; Costello, RW
      Function of pulmonary neuronal M-2 muscarinic receptors in stable chronic obstructive pulmonary disease

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    69. Wohlsen, A; Uhlig, S; Martin, C
      Immediate allergic response in small airways

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    70. Piedimonte, G
      Neural mechanisms of respiratory syncytial virus-induced inflammation and prevention of respiratory syncytial virus sequelae

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    71. Busch, T; Bartsch, P; Pappert, D; Grunig, E; Hildebrandt, W; Elser, H; Falke, KJ; Swenson, ER
      Hypoxia decreases exhaled nitric oxide in mountaineers susceptible to high-altitude pulmonary edema

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    72. Kotaru, C; Coreno, A; Skowronski, M; Ciufo, R; McFadden, ER
      Exhaled nitric oxide and thermally induced asthma

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    73. Sandford, AJ; Chagani, T; Weir, TD; Connett, JE; Anthonisen, NR; Pare, PD
      Susceptibility genes for rapid decline of lung function in the Lung HealthStudy

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    74. Takeyama, K; Fahy, JV; Nadel, JA
      Relationship of epidermal growth factor receptors to goblet cell production in human bronchi

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    75. Reardon, RF; Martel, M
      Intubating laryngeal mask airway: Suggestions for use in the emergency department

      ACADEMIC EMERGENCY MEDICINE
    76. Peel, C; Ballard, D
      Reproducibility of the 6-minute-walk test in older women

      JOURNAL OF AGING AND PHYSICAL ACTIVITY
    77. Bell, RB; Turvey, TA
      Skeletal advancement for the treatment of obstructive sleep apnea in children

      CLEFT PALATE-CRANIOFACIAL JOURNAL
    78. Huerta, C; Rodriguez, LAG; Moller, CS; Arellano, FM
      The risk of obstructive airways disease in a glaucoma population

      PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
    79. Little, FF; Cruikshank, WW; Center, DM
      IL-9 stimulates release of chemotactic factors from human bronchial epithelial cells

      AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
    80. Kreda, SM; Gynn, MC; Fenstermacher, DA; Boucher, RC; Gabriel, SE
      Expression and localization of epithelial aquaporins in the adult human lung

      AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
    81. King, KA; Hu, CP; Rodriguez, MM; Romaguera, R; Jiang, XB; Piedimonte, G
      Exaggerated neurogenic inflammation and substance p receptor upregulation in RSV-infected weanling rats

      AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
    82. Wang, XR; Zhang, YL; Amberson, A; Engelhardt, JF
      New models of the tracheal airway define the glandular contribution to airway surface fluid and electrolyte composition

      AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
    83. Uings, IJ; Balasubramanian, P; McLoughlin, PG; Yin, Q; Dash, L; Beresford, A; Kearney, S; Barrett, RW; McKinnon, M; England, BP
      Modified peptide antagonists of interleukin 5 exhibit extended in vivo persistence but restricted species specificity

      CYTOKINE
    84. Panitch, HB
      Bronchiolitis in infants

      CURRENT OPINION IN PEDIATRICS
    85. Cavarra, E; Lucattelli, M; Gambelli, F; Bartalesi, B; Fineschi, S; Szarka, A; Giannerini, F; Martorana, PA; Lungarella, G
      Human SLPI inactivation after cigarette smoke exposure in a new in vivo model of pulmonary oxidative stress

      AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
    86. Janssen, LJ; Hwa, LC; Netherton, S
      Responsiveness of canine bronchial vasculature to excitatory stimuli and to cooling

      AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
    87. Takeyama, K; Jung, B; Shim, JJ; Burgel, PR; Pick, TD; Ueki, IF; Protin, U; Kroschel, P; Nadel, JA
      Activation of epidermal growth factor receptors is responsible for mucin synthesis induced by cigarette smoke

      AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
    88. Larangeira, AP; Silva, AR; Gomes, RN; Penido, C; Henriques, MGMO; Castro-Faria-Neto, HC; Bozza, PT
      Mechanisms of allergen- and LPS-induced bone marrow eosinophil mobilization and eosinophil accumulation into the pleural cavity: a role for CD11b/CD18 complex

      INFLAMMATION RESEARCH
    89. Thorn, J
      The inflammatory response in humans after inhalation of bacterial endotoxin: a review

      INFLAMMATION RESEARCH
    90. Kasai, M; Kurasawa, K; Nakajima, H; Iwamoto, I
      T cell vaccination eliminates antigen-specific T cells and prevents antigen-induced eosinophil recruitment into the tissue

      INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
    91. Scichilone, N; Pyrgos, G; Kapsali, T; Anderlind, C; Brown, R; Permutt, S; Togias, A
      Airways hyperresponsiveness and the effects of lung inflation

      INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
    92. Frew, AJ; Salvi, S; Holgate, ST; Kelly, F; Stenfors, N; Nordenhall, C; Blomberg, A; Sandstrom, T
      How concentrations of diesel exhaust induce a neutrophilic response and upregulate IL-8 mRNA in healthy subjects but not in asthmatic volunteers

      INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
    93. Roger, P; Gascard, JP; Bara, J; de Montpreville, VT; Brink, C
      MUC5AC mucin release from human airways in vitro: Effects of indomethacin and Bay X1005

      MEDIATORS OF INFLAMMATION
    94. Frischer, T; Studnicka, M; Halmerbauer, G; Horak, F; Gartner, C; Tauber, E; Koller, DY
      Ambient ozone exposure is associated with eosinophil activation in healthychildren

      CLINICAL AND EXPERIMENTAL ALLERGY
    95. Greiff, L; Petersen, H; Mattsson, E; Andersson, M; Erjefalt, JS; Linden, M; Svensson, C; Persson, CGA
      Mucosal output of eotaxin in allergic rhinitis and its attenuation by topical glucocorticosteroid treatment

      CLINICAL AND EXPERIMENTAL ALLERGY
    96. Mastalerz, L; Sanak, M; Szczeklik, A
      Serum interleukin-5 in aspirin-induced asthma

      CLINICAL AND EXPERIMENTAL ALLERGY
    97. Di Stefano, A; Capelli, A; Lusuardi, M; Caramori, G; Balbo, P; Ioli, F; Sacco, S; Gnemmi, I; Brun, P; Adcock, IM; Balbi, B; Barnes, PJ; Chung, KF; Donner, CF
      Decreased T lymphocyte infiltration in bronchial biopsies of subjects withsevere chronic obstructive pulmonary disease

      CLINICAL AND EXPERIMENTAL ALLERGY
    98. Peebles, RS; Hamilton, RG; Lichtenstein, LM; Schlosberg, M; Liu, MC; Proud, D; Togias, A
      Antigen-specific IgE and IgA antibodies in bronchoalveolar lavage fluid are associated with stronger antigen-induced late phase reactions

      CLINICAL AND EXPERIMENTAL ALLERGY
    99. Bjermer, L
      History and future perspectives of treating asthma as a systemic and smallairways disease

      RESPIRATORY MEDICINE
    100. D'Amato, G; Liccardi, G; D'Amato, M; Cazzola, M
      The role of outdoor air pollution and climatic changes on the rising trends in respiratory allergy

      RESPIRATORY MEDICINE


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Documento generato il 16/07/20 alle ore 06:06:58