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Interferon gamma induction in human melanoma cell/allogeneic leukocyte co-cultures is enhanced by interleukin 18 but drug resistant melanoma cells are poorer inducers of IFN-gamma
INTERNATIONAL IMMUNOPHARMACOLOGY
Ontogeny of bladder agenesis in rats induced by adriamycin
BJU INTERNATIONAL
The effect of hydrophobe chemical structure and chain length on the solubilization of griseofulvin in aqueous micellar solutions of block copoly(oxyalkylene)s
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
Molecular characterisation of camptothecin-induced mutations at the hprt locus in Chinese hamster cells
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Multivariate evaluation of doxorubicin surface-enhanced Raman spectra
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
Chemotherapy-induced chromosomal damage in peripheral blood lymphocytes ofcancer patients supplemented with antioxidants or placebo
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Oxidative mutagenesis of doxorubicin-Fe(III) complex
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
Characteristics of antitumour activity of cepharanthin against a human adenosquamous cell carcinoma cell line
ORAL ONCOLOGY
Mitral regurgitation after anthracycline treatment for childhood malignancy
HEART
Evaluation of the anti-tumour activity of liposomal doxorubicin coated with hydrophilic polymers in tumour-bearing mice
STP PHARMA SCIENCES
Can interleukin-2 reverse anthracyclin chemoresistance in metastatic soft tissue sarcoma patients. Results of a prospective phase II clinical trial
EUROPEAN CYTOKINE NETWORK
Neoadjuvant chemotherapy for patients with synchronous multifocal osteosarcoma: Results in eleven cases
JOURNAL OF CHEMOTHERAPY
Modulation of Akt activity by doxorubicin in breast cancer cells
JOURNAL OF CHEMOTHERAPY
Neoadjuvant chemotherapy for high grade osteosarcoma of the extremities: Long-term results for patients treated according to the rizzoli IOR/OS-3b protocol
JOURNAL OF CHEMOTHERAPY
Modification of thermosensitivity and chemosensitivity induced by combinedtreatments with hyperthermia and adriamycin
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Antigen-specific downregulation of T cells by doxorubicin delivered through a recombinant MI-IC II-peptide chimera
NATURE BIOTECHNOLOGY
Cellular and biophysical evidence for interactions between adenosine triphosphate and P-glycoprotein substrates: functional implications for adenosine triphosphate/drug cotransport in P-glycoprotein overexpressing tumor cells and in P-glycoprotein low-level expressing erythrocytes
BLOOD CELLS MOLECULES AND DISEASES
Radiosensitization by gemcitabine in p53 wild-type and mutant MCF-7 breastcarcinoma cell lines
CLINICAL CANCER RESEARCH
Frederine, a new and promising protector against doxorubicin-induced cardiotoxicity
CLINICAL CANCER RESEARCH
Motexafin gadolinium: A redox active drug that enhances the efficacy of bleomycin and doxorubicin
CLINICAL CANCER RESEARCH
Attenuation of the acute adriamycin-induced cardiac and hepatic oxidative toxicity by N-(2-mercaptopropionyl) glycine in rats
FREE RADICAL RESEARCH
Induction of proteinuric chronic glomerular disease in the rat (Rattus norvegicus) by intracardiac injection of doxorubicin hydrochloride
CONTEMPORARY TOPICS IN LABORATORY ANIMAL SCIENCE
Structure-activity relationship studies on the potent multidrug resistance(MDR) modulator 2-(3,4-dimethoxyphenyl)-2-(methylethyl)-5-[(anthr-9-yl)methylamino]pentanenitrile (MM 36)
MEDICINAL CHEMISTRY RESEARCH
Experimental animal wound models
WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE
Propionyl-L-carnitine as protector against adriamycin-induced cardiomyopathy
PHARMACOLOGICAL RESEARCH
The preventive role of deferoxamine against acute doxorubicin-induced cardiac, renal and hepatic toxicity in rats
PHARMACOLOGICAL RESEARCH
Novel polymer-DNA hybrid polymeric micelles composed of hydrophobic poly(D,L-lactic-co-glycolic acid) and hydrophilic oligonucleotides
BIOCONJUGATE CHEMISTRY
Effectiveness of interferon-alfa and mid-cycle chemotherapy added to an anthracycline-based regimen in the treatment of aggressive non-Hodgkin's lymphoma
LEUKEMIA & LYMPHOMA
Immunoprotective therapy with targeted anticancer drugs
MACROMOLECULAR SYMPOSIA
Mechanisms of anticancer action of HPMA copolymer-bound doxorubicin
MACROMOLECULAR SYMPOSIA
Doxorubicin cardiotoxicity in children: Reduced incidence of cardiac dysfunction associated with continuous-infusion schedules
ONCOLOGY REPORTS
A synthetic triptycene bisquinone, which blocks nucleoside transport and induces DNA fragmentation, retains its cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines
INTERNATIONAL JOURNAL OF ONCOLOGY
Effect of thermosensitive liposomal doxorubicin with hyperthermia on primary tumor and lung metastases in hamster osteosarcoma
INTERNATIONAL JOURNAL OF ONCOLOGY
Activation of caspase-3 in renal cell carcinoma cells by anthracyclines or5-fluorouracil
INTERNATIONAL JOURNAL OF ONCOLOGY
Immunomodulation by anticancer chemotherapy: More is not always better (review)
INTERNATIONAL JOURNAL OF ONCOLOGY
ACE inhibition preserves heparan sulfate proteoglycans in the glomerular basement membrane of rats with established adriamycin nephropathy
EXPERIMENTAL NEPHROLOGY
Cardiolipin is essential for higher proton translocation activity of reconstituted F-o
SCIENCE IN CHINA SERIES C-LIFE SCIENCES
Electrochemical behavior of adriamycin at a cobalt ion implantation modified electrode
CHINESE SCIENCE BULLETIN
Modification of cell response to insulin by membrane-acting agents in rat white adipocytes: Analysis of structural features by computational simulation
BIOORGANIC & MEDICINAL CHEMISTRY
Hair and cancer chemotherapy: consequences and nursing care - a literaturestudy
EUROPEAN JOURNAL OF CANCER CARE
Anthracyclines in breast cancer: therapy and issues of toxicity
BREAST
Improving the therapeutic index when using Myocet (TM) in the treatment ofmetastatic breast cancer
BREAST
Liposomal doxorubicin (Myocet (TM)) and conventional anthracyclines: a comparison
BREAST
Formaldehyde-mediated modification of natural deoxyguanosine with amines: One-pot cyclization as a molecular model for genotoxicity
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Effects of water-soluble antioxidant from spinach, NAO, on doxorubicin-induced heart injury
HUMAN & EXPERIMENTAL TOXICOLOGY
Results of a phase III prospective, randomised trial, comparing mitoxantrone and vinorelbine (MV) in combination with standard FAC/FEC in front-line therapy of metastatic breast cancer
EUROPEAN JOURNAL OF CANCER
Modification of doxorubicin-induced cardiotoxicity: effect of essential fatty acids and ICRF-187 (dexrazoxane)
EUROPEAN JOURNAL OF CANCER
Biodistribution and antitumour efficacy of long-circulating N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin conjugates in nude mice
EUROPEAN JOURNAL OF CANCER
Establishment and characterization of adriamycin-resistant human colorectal adenocarcinoma HCT-15 cell lines with multidrug resistance
ANTI-CANCER DRUGS
Glutathione-S-transferase-pi expression regulates sensitivity to glutathione-doxorubicin conjugate
ANTI-CANCER DRUGS
Relationship between cytocidal activity and glutathione-S-transferase inhibition using doxorubicin coupled to stereoisomers of glutathione with different substrate specificity
ANTI-CANCER DRUGS
Sequential gene expression of P-glycoprotein (P-gp), multidrug resistance-associated protein (MRP) and lung resistance protein: functional activity of P-gp and MRP present in the doxorubicin-resistant human K562 cell lines
ANTI-CANCER DRUGS
Doxorubicin-peptide conjugates overcome multidrug resistance
ANTI-CANCER DRUGS
Approach to a multiparametric sensor-chip-based tumor chemosensitivity assay
ANTI-CANCER DRUGS
Dietary oils high in oleic acid, but with different non-glyceride contents, have different effects on lipid profiles and peroxidation in rabbit hepatic mitochondria
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Comparison of echocardiography and radionuclide ventriculography in the follow-up of left ventricular systolic function in adult lymphoma patients during doxorubicin therapy
JOURNAL OF INTERNAL MEDICINE
Role of gamma-linolenic acid in counteracting doxorubicin induced damage in cultured rat cardiomyocytes
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV
ONCOGENE
Increased p53 phosphorylation after microtubule disruption is mediated in a microtubule inhibitor- and cell-specific manner
ONCOGENE
The importance of peripheral blood leukocytes and macrophage infiltration on bronchial wall wound healing in rats treated preoperatively with anticancer agents
SURGERY TODAY
Analysis of the development of normal foregut and tracheoesophageal fistula in an adriamycin rat model using three-dimensional image reconstruction
SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY
New quinone-amino acid conjugates linked via a vinylic spacer
AMINO ACIDS
Novel N-quinonyl amino acids and their transformation to 3-substituted p-isoxazinones
AMINO ACIDS
Association of nitric oxide production and apoptosis in a model of experimental nephropathy
NEPHROLOGY DIALYSIS TRANSPLANTATION
Altered antioxidant defence in a mouse adriamycin model of glomerulosclerosis
NEPHROLOGY DIALYSIS TRANSPLANTATION
Nuclear targeting and retention of anthracycline antitumor drugs in sensitive and resistant tumor cells
CURRENT MEDICINAL CHEMISTRY
Additive effect of adenovirus-mediated E2F-1 gene transfer and topoisomerase II inhibitors on apoptosis in human osteosarcoma cells
CANCER GENE THERAPY
Cardiac function following combination therapy with paclitaxel and doxorubicin: An analysis of 657 women with advanced breast cancer
ANNALS OF ONCOLOGY
Anthracycline-induced acute cardiotoxicity in adults treated for leukaemia- Analysis of the clinico-pathological aspects of documented acute anthracycline-induced cardiotoxicity inpatients treated for acute leukaemia at theUniversity Hospital of Zurich, Switzerland, between 1990 and 1996
ANNALS OF ONCOLOGY
A randomized trial of four cycles of adjuvant AC (adriamycin plus cyclophosphamide) +/- two cycles of EP (etoposide plus cisplatin) in node positive patients with breast cancer
ANNALS OF ONCOLOGY
Cisplatin and vinorelbine in advanced and/or metastatic adenocarcinoma of the endometrium: A new highly active chemotherapeutic regimen
ANNALS OF ONCOLOGY
Cyclophosphamide, adriamycin and dexamethasone (CAD) is a highly effectivetherapy for patients with advanced multiple myeloma
ANNALS OF ONCOLOGY
Doxorubicin toxicity to the skin: possibility of protection with antioxidants enriched yeast
JOURNAL OF DERMATOLOGICAL SCIENCE
Heat stress protects against electrophysiological damages induced by acutedoxorubicin exposure in isolated rat hearts
CARDIOVASCULAR DRUGS AND THERAPY
Reversal of vinblastine resistance in human leukemic cells by haloperidol and dihydrohaloperidol
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Mechanism of resistance to oxidative stress in doxorubicin resistant cells
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Characteristics of tissue distribution of various polysaccharides as drug carriers: Influences of molecular weight and anionic charge on tumor targeting
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Receptor mediated endocytosis and cytotoxicity of transferrin-mitomycin c conjugate in the HepG2 cell and primary cultured rat hepatocyte
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Synergistic effect of indomethacin with adriamycin and cisplatin on tumor growth
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Changes in quantitative profile of extracellular matrix components in the kidneys of rats with adriamycin-induced nephropathy
JOURNAL OF VETERINARY MEDICAL SCIENCE
A new quinoline derivative MS-209 reverses multidrug resistance and inhibits multiorgan metastases by P-glycoprotein-expressing human small cell lungcancer cells
JAPANESE JOURNAL OF CANCER RESEARCH
Reversal of multidrug resistance by novel nitrophenyl pyrones, SNF4435C and D
JAPANESE JOURNAL OF CANCER RESEARCH
Intracellular levels of two cyclosporin derivatives valspodar (PSC 833) and cyclosporin a closely associated with multidrug resistance-modulating activity in sublines of human colorectal adenocarcinoma HCT-15
JAPANESE JOURNAL OF CANCER RESEARCH
Increased plasma endothelin-1 and cardiac nitric oxide during doxorubicin-induced cardiomyopathy
PHARMACOLOGY & TOXICOLOGY
Poly(HPMA)-coated liposomes demonstrate prolonged circulation in mice
JOURNAL OF LIPOSOME RESEARCH
A rapid assay for mitochondrial DNA damage and respiratory chain inhibition in the yeast Saccharomyces cerevisiae
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
Ceramide glycosylation potentiates cellular multidrug resistance
FASEB JOURNAL
Single agent chemotherapy with doxorubicin for feline lymphoma: A retrospective study of 19 cases (1994-1997)
JOURNAL OF VETERINARY INTERNAL MEDICINE
New synthetic flavonoids as potent protectors against doxorubicin-induced cardiotoxicity
FREE RADICAL BIOLOGY AND MEDICINE
Effect of mycophenolate mofetil on the progression of adriamycin nephropathy
RENAL FAILURE
Tubular cell lesion, albuminuria, and renal albumin handling in rats treated with adriamycin
RENAL FAILURE
Amine oxidase, spermine, and hyperthermia induce cytotoxicity in P-glycoprotein overexpressing multidrug resistant Chinese hamster ovary cells
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
Melatonin protects against cardiac toxicity of doxorubicin in rat
JOURNAL OF PINEAL RESEARCH
Effects of melatonin on doxorubicin cytotoxicity in sensitive and pleiotropically resistant tumor cells
JOURNAL OF PINEAL RESEARCH
Melatonin versus treatment against extra-hepatic bile vitamin E as protective oxidative stress after duct ligation in rats
JOURNAL OF PINEAL RESEARCH
Protective effect of melatonin against adriamycin toxicity in the rat
JOURNAL OF PINEAL RESEARCH
Effect of phosphatidic acid on human breast cancer cells exposed to doxorubicin
CANCER INVESTIGATION
Reduced cardiotoxicity and preserved antitumor efficacy of liposome-encapsulated doxorubicin and cyclophosphamide compared with conventional doxorubicin and cyclophosphamide in a randomized, multicenter trial of metastatic breast cancer
JOURNAL OF CLINICAL ONCOLOGY
Benefit of a high-dose epirubicin regimen in adjuvant chemotherapy for node-positive breast cancer patients with poor prognostic factors: 5-year follow-up results of French adjuvant study group 05 randomized trial
JOURNAL OF CLINICAL ONCOLOGY
Phase I and pharmacokinetic study of LU79553, a DNA intercalating bisnaphthalimide, in patients with solid malignancies
JOURNAL OF CLINICAL ONCOLOGY