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Targeting head and neck cancer by IL-2-mediated gene therapy: From bench to bedside - A review.
LARYNGO-RHINO-OTOLOGIE
Bolus high dose interleukin-2 for the treatment of malignant melanoma
ISRAEL MEDICAL ASSOCIATION JOURNAL
Critical role of IL-15-IL-15R for antigen-presenting cell functions in theinnate immune response
NATURE IMMUNOLOGY
Neoadiuvant treatment with intravesical interleukin-2 for recurrent superficial transitional bladder carcinoma Ta-T1/G1-2
JOURNAL OF IMMUNOTHERAPY
Human-SCID mouse chimeric models for the evaluation of anti-cancer therapies
TRENDS IN IMMUNOLOGY
Kidney cancer: The Cytokine Working Group experience (1986-2001) - Part I.IL-2-based clinical trials
MEDICAL ONCOLOGY
Kidney cancer: The Cytokine Working Group experience (1986-2001) - Part II: Management of IL-2 toxicity and studies with other cytokines
MEDICAL ONCOLOGY
Neuroendocrine and immune aspects of fibromyalgia
BIODRUGS
Expansion of cytotoxic CD3(+)CD56(+) cells from peripheral blood progenitor cells of patients undergoing autologous hematopoietic cell transplantation
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
Practical guidelines for the management of biochemotherapy-related toxicity in melanoma
CLINICAL CANCER RESEARCH
Augmentation of antitumor activity of an antibody-interleukin 2 immunocytokine with chemotherapeutic agents
CLINICAL CANCER RESEARCH
Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: Implications for immunotherapy
IMMUNITY
Survival in patients with recurrent squamous cell head and neck carcinoma treated with bio-chemotherapy
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
A phase I trial of intralesional rV-Tricom vaccine in the treatment of malignant melanoma
HUMAN GENE THERAPY
Treatment of refractory recurrent malignant glioma with adoptive cellular immunotherapy: a case report
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Adoptive cellular immunotherapy for the treatment of malignant gliomas
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
T-cell adoptive therapy of tumors: Mechanisms of improved therapeutic performance
CRITICAL REVIEWS IN IMMUNOLOGY
Dysregulation of telomerase activity and expression in lymphokine-activated killer cells from advanced cancer patients: Possible involvement in cancer-associated immunosuppression mechanism
ONCOLOGY REPORTS
Progress in the development of immunotherapy for the treatment of patientswith cancer
JOURNAL OF INTERNAL MEDICINE
Factors associated with response to high-dose interleukin-2 in patients with metastatic melanoma
JOURNAL OF CLINICAL ONCOLOGY
Systemic chemotherapy and chemoimmunotherapy for metastatic renal cell cancer
WORLD JOURNAL OF UROLOGY
Gamma/delta T cells provide innate immunity against renal cell carcinoma
CANCER IMMUNOLOGY IMMUNOTHERAPY
Dendritic-cell-peptide immunization provides immunoprotection against bcr-abl-positive leukemia in mice
CANCER IMMUNOLOGY IMMUNOTHERAPY
uPA and uPAR contribute to NK cell invasion through the extracellular matrix
ANTICANCER RESEARCH
Generation of cytotoxic effector lymphocytes by MLTC using tumor cells genetically modified to secrete interleukin-2
ANTICANCER RESEARCH
Phase IB study of 25-hydroxyvitamin D-3 treatment to diminish suppressor cells in head and neck cancer patients
HUMAN IMMUNOLOGY
T-helper cell-response to MHC class II-binding peptides of the renal cell carcinoma-associated antigen RAGE-1
IMMUNOBIOLOGY
Characterization of human non-small cell lung cancer (NSCLC) cell lines for expression of MHC, co-stimulatory molecules and tumor-associated antigens
LUNG CANCER
Palliative and therapeutic activity of IL-2 immunotherapy in unresectable malignant pleural mesothelioma with pleural effusion - Results of a phase II study on 31 consecutive patients
LUNG CANCER
Effects of interleukin-2 on the expression of corticotropin-releasing hormone in nerves and lymphoid cells in secondary lymphoid organs from the Fischer 344 rat
JOURNAL OF NEUROIMMUNOLOGY
Production and characterization of monoclonal antibodies reactive with thechicken interleukin-15 receptor alpha chain
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
Molecular, cellular, and functional characterization of chicken cytokines homologous to mammalian IL-15 and IL-2
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
Anticancer drug-induced kidney disorders - Incidence, prevention and management
DRUG SAFETY
Immunological and molecular analysis of the sentinel lymph node: A potential approach to predict outcome, tailor therapy, and optimize parameters fortumor vaccine development
JOURNAL OF CLINICAL PHARMACOLOGY
Cellular and molecular pharmacology of antiestrogen action and resistance
PHARMACOLOGICAL REVIEWS
Use of interleukin-2 in advanced renal carcinoma: meta-analysis and reviewof the literature
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
A literature analysis of prognostic factors for response and quality of response of patients with renal cell carcinoma to interleukin-2-based therapy
ONCOLOGY
Phase II trial of systemic recombinant interleukin-2 in the treatment of refractory nasopharyngeal carcinoma
ONCOLOGY
Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer
NEW ENGLAND JOURNAL OF MEDICINE
Progress in human tumour immunology and immunotherapy
NATURE
Immunogene therapy with interleukin-2-secreting fibroblasts for intracerebrally metastasizing breast cancer in mice
JOURNAL OF NEUROSURGERY
The IL-15R alpha chain signals through association with Syk in human B cells
JOURNAL OF IMMUNOLOGY
Cloning and characterization of a p53-related protein kinase expressed in interleukin-2-activated cytotoxic T-cells, epithelial tumor cell lines, andthe testes
JOURNAL OF BIOLOGICAL CHEMISTRY
Interleukin-2 receptor beta subunit-dependent and -independent regulation of intestinal epithelial tight junctions
JOURNAL OF BIOLOGICAL CHEMISTRY
Interleukin-15 prevents mouse mast cell apoptosis through STAT6-mediated Bcl-x(L) expression
JOURNAL OF BIOLOGICAL CHEMISTRY
Augmentation of death ligand-induced apoptosis by aminopeptidase inhibitors in human solid tumor cell lines
INTERNATIONAL JOURNAL OF CANCER
Immunotherapy of metastatic kidney cancer
INTERNATIONAL JOURNAL OF CANCER
Long-term immunotherapy with low-dose interleukin-2 and interferon-alpha in the treatment of patients with advanced renal cell carcinoma
CANCER
Allogeneic hematopoietic cell transplantation in solid tumors
BULLETIN DU CANCER
Cell therapy for solid tumors
BULLETIN DU CANCER
Modulation of A-NK cell rigidity: In vitro characterization and in vivo implications for cell delivery
BIORHEOLOGY
Differential effects of IL-2 and IL-15 on expression of IL-2 receptor alpha
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Interleukin-2-induced small unilamellar vesicle coalescence
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
Influence of cytokines and autologous lymphokine-activated killer cells onleukemic bone marrow cells and colonies in AML
ACTA HAEMATOLOGICA
Decreased tolerance to interleukin-2 with repeated courses of therapy in patients with metastatic melanoma or renal cell cancer
JOURNAL OF IMMUNOTHERAPY
An acidic microenvironment inhibits antitumoral non-major histocompatibility complex-restricted cytotoxicity: Implications for cancer immunotherapy
JOURNAL OF IMMUNOTHERAPY
Posttransplant adoptive immunotherapy with activated natural killer cells in patients with metastatic breast cancer
JOURNAL OF IMMUNOTHERAPY
From leukocyte reduction to leukocyte transfusion: the immunological effects of transfused leukocytes
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
Negative inotropic effects of recombinant interleukin 2 in patients without left ventricular dysfunction
EUROPEAN JOURNAL OF HEART FAILURE
Cytokine therapy for cancer
CURRENT PHARMACEUTICAL DESIGN
Interleukin-2 in cancer therapy - Uses and optimum management of adverse effects
BIODRUGS
Subunit structure of the high and low affinity human interleukin-15 receptors
EUROPEAN CYTOKINE NETWORK
Randomized study of recombinant interleukin-2 after autologous bone marrowtransplantation for acute leukemia in first complete remission
EUROPEAN CYTOKINE NETWORK
Circumvention of tumor cell escape following specific immunotherapy
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
Long-term survival update for high-dose recombinant interleukin-2 in patients with renal cell carcinoma
CANCER JOURNAL FROM SCIENTIFIC AMERICAN
Cytokine therapy in renal cell cancer
UROLOGIC ONCOLOGY
Phase I trial of TALL-104 cells in patients with refractory metastatic breast cancer
CLINICAL CANCER RESEARCH
Effect of perilesional injections of PEG-interleukin-2 on basal cell carcinoma
DERMATOLOGIC SURGERY
Reduction of side effects of intravesical therapy with bacille Calmette-Guerin by pentoxifylline? An in vitro approach
CLINICAL INFECTIOUS DISEASES
Interferon gamma inhibits proliferation and hyaluronic acid adhesion of human malignant glioma cells in vitro
CYTOKINE
CD4(+) T cells in adoptive immunotherapy and the indirect mechanism of tumor rejection
CRITICAL REVIEWS IN IMMUNOLOGY
Protein-bound polysaccharide increases survival in resected gastric cancercases stratified with a preoperative granulocyte and lymphocyte count
ONCOLOGY REPORTS
Intermittent adjuvant chemo-immunotherapy after resection of non-small cell lung cancer with multilevel mediastinal lymph node metastasis
ONCOLOGY REPORTS
Increased ICAM-1 expression in transformed human oral epithelial cells: molecular mechanism and functional role in peripheral blood mononuclear cell adhesion and lymphokine-activated-killer cell cytotoxicity
INTERNATIONAL JOURNAL OF ONCOLOGY
Gene transfer of human interferon gamma complementary DNA into a renal cell carcinoma line enhances MHC-restricted cytotoxic T lymphocyte recognitionbut suppresses non-MHC-restricted effector cell activity
GENE THERAPY
Interleukin-2 plus chemotherapy for patients with metastatic melanoma
MELANOMA RESEARCH
Macrophage-mediated immunostimulation modulates therapeutic efficacy of interleukin-2 based chemoimmunotherapy in advanced metastatic melanoma patients
MELANOMA RESEARCH
Inhalational interleukin-2 liposomes for pulmonary metastases: a phase I clinical trial
ANTI-CANCER DRUGS
Increased non-major histocompatibility complex-restricted lytic activity in melanoma patients vaccinated with cytokine gene-transfected autologous tumor cells
CANCER GENE THERAPY
Therapy-related changes of CD20(+) and CD45RO(+) lymphocyte subsets in chronic myeloid leukemia (CML): An immunohistochemical and morphometric study on sequential trephine biopsies of the bone marrow
MODERN PATHOLOGY
Lymphokines post autologous peripheral blood stem cell transplantation in children
PEDIATRIC HEMATOLOGY AND ONCOLOGY
Clinical ineffectiveness of IL-2 and/or IFN alpha administration after autologous PBSC transplantation in pediatric oncological patients
PEDIATRIC HEMATOLOGY AND ONCOLOGY
Systemic adoptive T-cell immunotherapy in recurrent and metastatic carcinoma of the head and neck - A phase 1 study
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
Immunity and lung cancer: perspectives for an antitumor vaccine
REVUE DES MALADIES RESPIRATOIRES
The use and development of retroviral vectors to deliver cytokine genes for cancer therapy
CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS
Effect of cytokine therapy on survival for patients with advanced renal cell carcinoma
JOURNAL OF CLINICAL ONCOLOGY
Impact of the number of treatment courses on the clinical response of patients who receive high-dose bolus interleukin-2
JOURNAL OF CLINICAL ONCOLOGY
Early depressive symptoms in cancer patients receiving interleukin 2 and/or interferon alfa-2b therapy
JOURNAL OF CLINICAL ONCOLOGY
Nonlymphoid cultured cells possess a system controlling cellular compatibility
JOURNAL OF CELLULAR BIOCHEMISTRY
IL-12 acid IL-2 potentiate the in vitro tumor-specific activity of peripheral blood cells from cervical cancer patients
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Six-year disease-free survival of a patient with metastatic eyelid squamous cell carcinoma and colon adenocarcinoma after repeated postoperative adoptive immunotherapy
JAPANESE JOURNAL OF CLINICAL ONCOLOGY
Polyethylene glycol-modified concanavalin A as an effective agent to stimulate anti-tumor cytotoxicity
CANCER DETECTION AND PREVENTION
gamma delta T cells lyse autologous and allogenic oesophageal tumours: involvement of heat-shock proteins in the tumour cell lysis
CANCER IMMUNOLOGY IMMUNOTHERAPY
Immunotherapy for renal carcinoma: theoretical basis and current standard of care
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
BCG's mechanism of action - Increasing our understanding
EUROPEAN UROLOGY
Interstitial fluid pressure is increased in renal cell carcinoma xenografts
UROLOGICAL RESEARCH
Sustained ventricular tachycardia and its successful prophylaxis during high-dose bolus interleukin-2 therapy for metastatic renal cell carcinoma
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
Pilot study of immunotherapy with interleukin-2 after autologous stem celltransplantation in advanced breast cancers
ANTICANCER RESEARCH
Induction of tumor-specific antitumor immunity after chemotherapy with cisplatin in mice bearing MOPC-104E plasmacytoma by modulation of MHC expression on tumor surface
ANTICANCER RESEARCH
Adoptive immunotherapy: present status and perspectives in cancer treatment.
REVUE DE MEDECINE INTERNE