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    1. Puglielli, L; Konopka, G; Pack-Chung, E; Ingano, LAM; Berezovska, O; Hyman, BT; Chang, TY; Tanzi, RE; Kovacs, DM
      Acyl-coenzyme A : cholesterol acyltransferase modulates the generation of the amyloid beta-peptide

      NATURE CELL BIOLOGY
    2. Batetta, B; Mulas, MF; Petruzzo, P; Putzolu, M; Bonatesta, RR; Sanna, F; Cappai, A; Brotzu, G; Dessi, S
      Opposite pattern of MDR1 and caveolin-1 gene expression in human atherosclerotic lesions and proliferating human smooth muscle cells

      CELLULAR AND MOLECULAR LIFE SCIENCES
    3. Yamaguchi, J; Hachiuma, K; Kimura, Y; Ogawa, N; Higuchi, S
      Highly sensitive determination of TS-962 (HL-004), a novel acyl-CoA : cholesterol acyltransferase inhibitor, in rat and rabbit plasma by liquid chromatography and atmospheric pressure chemical ionization-tandem mass spectrometry combined with a column-switching technique

      JOURNAL OF CHROMATOGRAPHY B
    4. Best, JD; Jenkins, AJ
      Novel agents for managing dyslipidaemia

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    5. Doshi, R; Wu, J; Fishelevich, R; Rodriguez, A
      Update on the role of acyl-CoA : cholesterol acyltransferase inhibitors inatherosclerosis

      EXPERT OPINION ON THERAPEUTIC PATENTS
    6. Kaneko, K; Uchida, K; Kobayashi, T; Miura, K; Tanokura, K; Hoshino, K; Kato, I; Onoue, M; Yokokura, T
      Sex-dependent toxicity of a novel acyl-CoA : cholesterol acyltransferase inhibitor, YIC-C8-434, in relation to sex-specific forms of cytochrome P450 in rats

      TOXICOLOGICAL SCIENCES
    7. Robertson, DG; Breider, MA; Milad, MA
      Preclinical safety evaluation of avasimibe in beagle dogs: An ACAT inhibitor with minimal adrenal effects

      TOXICOLOGICAL SCIENCES
    8. Phan, CT; Tso, P
      Intestinal lipid absorption and transport

      FRONTIERS IN BIOSCIENCE
    9. Brown, WV
      New therapies on the horizon

      AMERICAN JOURNAL OF MANAGED CARE
    10. Petruzzo, P; Cappai, A; Brotzu, G; Batetta, B; Putzolu, M; Mulas, MF; Bonatesta, RR; Sanna, F; Dessi, S
      Lipid metabolism and molecular changes in normal and atherosclerotic vessels

      EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
    11. McLay, IM; Halley, F; Souness, JE; McKenna, J; Benning, V; Birrell, M; Burton, B; Belvisi, M; Collis, A; Constan, A; Foster, M; Hele, D; Jayyosi, Z; Kelley, M; Maslen, C; Miller, G; Ouldelhkim, MC; Page, K; Phipps, S; Pollock, K; Porter, B; Ratcliffe, AI; Redford, EJ; Webber, S; Slater, B; Thybaud, V; Wilsher, N
      The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a goodoral anti-arthritic efficacy

      BIOORGANIC & MEDICINAL CHEMISTRY
    12. Chang, TY; Chang, CCY; Lin, S; Yu, CJ; Li, BL; Miyazaki, A
      Roles of acyl-coenzyme A : cholesterol acyltransferase-1 and-2

      CURRENT OPINION IN LIPIDOLOGY
    13. Rudel, LL; Lee, RG; Cockman, TL
      Acyl coenzyme A : cholesterol acyltransferase types 1 and 2: structure andfunction in atherosclerosis

      CURRENT OPINION IN LIPIDOLOGY
    14. Kushwaha, RS; VandeBerg, JF; Jackson, EM; VandeBerg, JL
      High and low responding strains of laboratory opossums differ in sterol 27-hydroxylase and acyl-coenzyme A : cholesterol acyltransferase activities on a high cholesterol diet

      JOURNAL OF NUTRITIONAL BIOCHEMISTRY
    15. Yamaguchi, J; Matsuno, Y; Hachiuma, K; Ogawa, N; Higuchi, S
      A strategy for quantitative bioanalysis of non-polar neutral compounds by liquid chromatography/electrospray ionization tandem mass spectrometry: determination of TS-962, a novel acyl-CoA : cholesterol acyltransferase inhibitor, in rabbit aorta and liver tissues

      RAPID COMMUNICATIONS IN MASS SPECTROMETRY
    16. Milliat, F; Ferezou, J; Delhon, A; Lutton, C
      Overexpression of SR-BI in hamsters treated with a novel ACAT inhibitor (F12511)

      COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES
    17. Park, YB; Do, KM; Bok, SH; Lee, MK; Jeong, TS; Choi, MS
      Interactive effect of hesperidin and vitamin E supplements on cholesterol metabolism in high cholesterol-fed rats

      INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH
    18. Moon, KD; Back, SS; Kim, JH; Jeon, SM; Lee, MK; Choi, MS
      Safflower seed extract lowers plasma and hepatic lipids in rats fed high-cholesterol diet

      NUTRITION RESEARCH
    19. Pandak, WM; Schwarz, C; Hylemon, PB; Mallonee, D; Valerie, K; Heuman, DM; Fisher, RA; Redford, K; Vlahcevic, ZR
      Effects of CYP7A1 overexpression on cholesterol and bile acid homeostasis

      AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
    20. Nordskog, BK; Phan, CT; Nutting, DF; Tso, P
      An examination of the factors affecting intestinal lymphatic transport of dietary lipids

      ADVANCED DRUG DELIVERY REVIEWS
    21. Shen, H; Howles, P; Tso, P
      From interaction of lipidic vehicles with intestinal epithelial cell membranes to the formation and secretion of chylomicrons

      ADVANCED DRUG DELIVERY REVIEWS
    22. Homan, R; Hamelehle, KL
      Influence of membrane partitioning on inhibitors of membrane-bound enzymes

      JOURNAL OF PHARMACEUTICAL SCIENCES
    23. Giovannoni, MP; Dal Piaz, V; Kwon, BM; Kim, MK; Kim, YK; Toma, L; Barlocco, D; Bernini, F; Canavesi, M
      5,6-diphenylpyridazine derivatives as acyl-CoA : cholesterol acyltransferase inhibitors

      JOURNAL OF MEDICINAL CHEMISTRY
    24. Guo, ZM; Cromley, D; Billheimer, JT; Sturley, SL
      Identification of potential substrate-binding sites in yeast and human acyl-CoA sterol acyltransferases by mutagenesis of conserved sequences

      JOURNAL OF LIPID RESEARCH
    25. Merzouk, H; Madani, S; Boualga, A; Prost, J; Bouchenak, M; Belleville, J
      Age-related changes in cholesterol metabolism in macrosomic offspring of rats with streptozotocin-induced diabetes

      JOURNAL OF LIPID RESEARCH
    26. Maung, KK; Miyazaki, A; Nomiyama, H; Chang, CCY; Chang, TY; Horiuchi, S
      Induction of acyl-coenzyme A : cholesterol acyltransferase-1 by 1,25-dihydroxyvitamin D-3 or 9-cis-retinoic acid in undifferentiated THP-1 cells

      JOURNAL OF LIPID RESEARCH
    27. Buhman, KK; Chen, HC; Farese, RV
      The enzymes of neutral lipid synthesis

      JOURNAL OF BIOLOGICAL CHEMISTRY
    28. Yang, JB; Duan, ZJ; Yao, W; Lee, O; Yang, L; Yang, XY; Sun, X; Chang, CCY; Chang, TY; Li, BL
      Synergistic transcriptional activation of human acyl-coenzyme A: Cholesterol acyltransterase-1 gene by interferon-gamma and all-trans-retinoic acid THP-1 cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    29. Aragane, K; Kojima, K; Fujinami, K; Kamei, J; Kusunoki, J
      Effect of F-1394, an acyl-CoA : cholesterol acyltransferase inhibitor, on atherosclerosis induced by high cholesterol diet in rabbits

      ATHEROSCLEROSIS
    30. Zoltowska, M; Ziv, E; Delvin, E; Stan, S; Bar-On, H; Kalman, R; Levy, E
      Circulating lipoproteins and hepatic sterol metabolism in Psammomys obesusprone to obesity, hyperglycemia and hyperinsulinemia

      ATHEROSCLEROSIS
    31. Bocan, TMA; Krause, BR; Rosebury, WS; Lu, XK; Dagle, C; Mueller, SB; Auerbach, B; Sliskovic, DR
      The combined effect of inhibiting both ACAT and HMG-CoA reductase may directly induce atherosclerotic lesion regression

      ATHEROSCLEROSIS
    32. Insull, W; Koren, M; Davignon, J; Sprecher, D; Schrott, H; Keilson, LM; Brown, AS; Dujovne, CA; Davidson, MH; McLain, R; Heinonen, T
      Efficacy and short-term safety of a new ACAT inhibitor, avasimibe, on lipids, lipoproteins, and apolipoproteins, in patients with combined hyperlipidemia

      ATHEROSCLEROSIS
    33. Perrey, S; Legendre, C; Matsuura, A; Guffroy, C; Binet, J; Ohbayashi, S; Tanaka, T; Ortuno, JC; Matsukura, T; Laugel, T; Padovani, P; Bellamy, F; Edgar, AD
      Preferential pharmacological inhibition of macrophage ACAT increases plaque formation in mouse and rabbit models of atherogenesis

      ATHEROSCLEROSIS
    34. Junquero, D; Bruniquel, F; N'Guyen, X; Autin, JM; Patoiseau, JF; Degryse, AD; Colpaert, FC; Delhon, A
      F 12511, a novel ACAT inhibitor, and atorvastatin regulate endogenous hypercholesterolemia in a synergistic manner in New Zealand rabbits fed a casein-enriched diet

      ATHEROSCLEROSIS
    35. Azuma, Y; Date, K; Ohno, K; Matsushiro, S; Nobuhara, Y; Yamada, T
      NTE-122, an acyl-CoA : cholesterol acyltransferase inhibitor, prevents theprogression of atherogenesis in cholesterol-fed rabbits

      JAPANESE JOURNAL OF PHARMACOLOGY
    36. Matsui, Y; Horiuchi, K; Yamamoto, K; Kanai, K
      Pharmacological properties of R-755, a novel acyl-CoA : cholesterol acyltransferase inhibitor, in cholesterol-fed rats, hamsters and rabbits

      JAPANESE JOURNAL OF PHARMACOLOGY
    37. Kusunoki, J; Hansoty, DK; Aragane, K; Fallon, JT; Badimon, JJ; Fisher, EA
      Acyl-CoA: Cholesterol acyltransferase inhibition reduces atherosclerosis in apolipoprotein E-deficient mice

      CIRCULATION
    38. Delsing, DJM; Offerman, EH; van Duyvenvoorde, W; van der Boom, H; de Wit, ECM; Gijbels, MJJ; van der Laarse, A; Jukema, JW; Havekes, LM; Princen, HMG
      Acyl-CoA: Cholesterol acyltransferase inhibitor avasimibe reduces atherosclerosis in addition to its cholesterol-lowering effect in ApoE*3-Leiden mice

      CIRCULATION
    39. Ohishi, K; Aiyama, R; Hatano, H; Yoshida, Y; Wada, Y; Yokoi, W; Sawada, H; Watanabe, T; Yokokura, T
      Structure-activity relationships of N-(3,5-dimethoxy-4-n-octyloxycinnamoyl)-N '-(3,4-dimethylphenyl)piperazine and analogues as inhibitors of acyl-CoA: Cholesterol O-acyltransferase

      CHEMICAL & PHARMACEUTICAL BULLETIN
    40. Chiwata, T; Aragane, K; Fujinami, K; Kojima, K; Ishibashi, S; Yamada, N; Kusunoki, J
      Direct effect of an acyl-CoA : cholesterol acyltransferase inhibitor, F-1394, on atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice

      BRITISH JOURNAL OF PHARMACOLOGY
    41. Junquero, D; Pilon, A; Carilla-Durand, E; Patoiseau, JF; Tarayre, JP; Torpier, G; Staels, B; Fruchart, JC; Colpaert, FC; Clavey, V; Delhon, A
      Lack of toxic effects of F 12511, a novel potent inhibitor of acylcoenzymeA: cholesterol O-acyltransferase, on human adrenocortical cells in culture

      BIOCHEMICAL PHARMACOLOGY
    42. Junquero, D; Oms, P; Carilla-Durand, E; Autin, JM; Tarayre, JP; Degryse, AD; Patoiseau, JF; Colpaert, FC; Delhon, A
      Pharmacological profile of F 12511, (S)-2 ',3 ',5 '-trimethyl-4 '-hydroxy-alpha-dodecylthioacetanilide a powerful and systemic acylcoenzyme A: cholesterol acyltransferase inhibitor

      BIOCHEMICAL PHARMACOLOGY
    43. Lee, CH; Jeong, TS; Choi, YK; Hyun, BH; Oh, GT; Kim, EH; Kim, JR; Han, JI; Bok, SH
      Anti-atherogenic effect of citrus flavonoids, naringin and naringenin, associated with hepatic ACAT and aortic VCAM-1 and MCP-1 in high cholesterol-fed rabbits

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    44. Song, BL; Qi, W; Yang, XY; Chang, CCY; Zhu, JQ; Chang, TY; Li, BL
      Organization of human ACAT-2 gene and its cell-type-specific promoter activity

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    45. Zehnder, LR; Hsung, RP; Wang, JS; Golding, GM
      A concise stereoselective route to the pentacyclic frameworks of arisugacin A and territrem B

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    46. Buhman, KF; Accad, M; Farese, RV
      Mammalian acyl-CoA: cholesterol acyltransferases

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
    47. Thompson, GR; Naoumova, RP
      Novel lipid-regulating drugs

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    48. Lemmens-Gruber, R
      Patent focus on agents affecting cardiovascular and renal functions November 1999-March 2000

      EXPERT OPINION ON THERAPEUTIC PATENTS
    49. Perry, DA
      Patent focus on agents for atherosclerosis: September 1999-February 2000

      EXPERT OPINION ON THERAPEUTIC PATENTS
    50. Li, L; Pownall, HJ
      Regulation of acyl-coenzyme A : cholesterol acyltransferase (ACAT) synthesis, degradation, and translocation by high-density lipoprotein(2) at a low concentration

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    51. Bocan, TMA; Krause, BR; Rosebury, WS; Mueller, SB; Lu, XK; Dagle, C; Major, T; Lathia, C; Lee, H
      The ACAT inhibitor avasimibe reduces macrophages and matrix metalloproteinase expression in atherosclerotic lesions of hypercholesterolemic rabbits

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    52. Kusunoki, J; Aragane, K; Kitamine, T; Kozono, H; Kano, K; Fujinami, K; Kojima, K; Chiwata, T; Sekine, Y
      Postprandial hyperlipidemia in streptozotocin-induced diabetic rats is dueto abnormal increase in intestinal acyl coenzyme A : cholesterol acyltransferase activity

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    53. Gesquiere, L; Loreau, N; Blache, D
      Role of the cyclic AMP-dependent pathway in free radical-induced cholesterol accumulation in vascular smooth muscle cells

      FREE RADICAL BIOLOGY AND MEDICINE
    54. Sandager, L; Dahlqvist, A; Banas, A; Stahl, U; Lenman, M; Gustavsson, M; Stymne, S
      An acyl-CoA : cholesterol acyltransferase (ACAT)-related gene is involved in the accumulation of triacylglycerols in Saccharomyces cerevisiae

      BIOCHEMICAL SOCIETY TRANSACTIONS
    55. Bok, SH; Shin, YW; Bae, KH; Jeong, TS; Kwon, YK; Park, YB; Choi, MS
      Effects of naringin and lovastatin on plasma and hepatic lipids in high-fat and high-cholesterol fed rats

      NUTRITION RESEARCH
    56. Huang, X; Fang, C
      Dietary trans fatty acids increase hepatic acyl-CoA: Cholesterol acyltransferase activity in hamsters

      NUTRITION RESEARCH
    57. Wilson, TA; Nicolosi, RJ; Chrysam, M; Kritchevsky, D
      Conjugated linoleic acid reduces early aortic atherosclerosis greater thanlinoleic acid in hypercholesterolemic hamsters

      NUTRITION RESEARCH
    58. Sakashita, N; Miyazaki, A; Takeya, M; Horiuchi, S; Chang, CCY; Chang, TY; Takahashi, K
      Acyl coenzyme A : cholesterol acyltransferase (ACAT) in macrophage-derivedfoam cells and its distribution in human organs

      ACTA HISTOCHEMICA ET CYTOCHEMICA
    59. Hua, DH; Takasu, K; Huang, XD; Millward, GS; Chen, Y; Fan, JM
      Palladium-mediated ring closure reactions. Facile syntheses of enantiopurebicyclic and tricyclic alkenones

      TETRAHEDRON
    60. Klier, AH; Alves, RJ; Auxiliadora, M; Prado, F; de Souza, JD; D'Accorso, NB
      Synthesis of new five membered nitrogen containing heterocycles bearing D-galactose side chains

      SYNTHETIC COMMUNICATIONS
    61. Whitman, SC; Daugherty, A; Post, SR
      Regulation of acetylated low density lipoprotein uptake in macrophages by pertussis toxin-sensitive G proteins

      JOURNAL OF LIPID RESEARCH
    62. Panousis, CG; Zuckerman, SH
      Regulation of cholesterol distribution in macrophage-derived foam cells byinterferon-gamma

      JOURNAL OF LIPID RESEARCH
    63. Accad, M; Smith, SJ; Newland, DL; Sanan, DA; King, LE; Linton, MF; Fazio, S; Farese, RV
      Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA : cholesterol acyltransferase 1

      JOURNAL OF CLINICAL INVESTIGATION
    64. Obata, R; Sunazuka, T; Harigaya, Y; Hayashi, M; Rho, MC; Tomoda, H; Omura, S
      Structure-activity relationships study of pyripyropenes: Reversal of cancer cell multidrug resistance

      JOURNAL OF ANTIBIOTICS
    65. Rho, MC; Hayashi, M; Fukami, A; Obata, R; Sunazuka, T; Tomoda, H; Komiyama, K; Omura, S
      Reversal of multidrug resistance by 7-O-benzoylpyripyropene A in multidrug-resistant tumor cells

      JOURNAL OF ANTIBIOTICS
    66. Letterie, GS
      Impact of subdermal norgestrel on hepatic acyl-coenzyme A : cholesterol-acyltransferase (ACAT) activity: Possible antiatherogenic effect

      CONTRACEPTION
    67. Kamiya, S; Shirahase, H; Yoshimi, A; Nakamura, S; Kanda, M; Matsui, H; Kasai, M; Takahashi, K; Kurahashi, K
      Bioavailable acyl-CoA: Cholesterol acyltransferase inhibitor with anti-peroxidative activity: Synthesis and biological activity of novel indolinyl amide and urea derivatives

      CHEMICAL & PHARMACEUTICAL BULLETIN
    68. Murakami, M; Kobayashi, K; Hirai, K
      Enantioselective synthesis of the key intermediate of the acyl-CoA: Cholesterol acyltransferase (ACAT) inhibitor (R-106578) using 2,2 '-bis(diphenylphosphino)-1,1'-binaphthyl (BINAP)-Ru(OAc)(2) as a catalyst

      CHEMICAL & PHARMACEUTICAL BULLETIN
    69. Yeung, CHT; Yang, L; Huang, Y; Wang, J; Chen, ZY
      Dietary conjugated linoleic acid mixture affects the activity of intestinal acyl coenzyme A: cholesterol acyltransferase in hamsters

      BRITISH JOURNAL OF NUTRITION
    70. Ohgami, N; Kuniyasu, A; Furukawa, K; Miyazaki, A; Hakamata, H; Horiuchi, S; Nakayama, H
      Glibenclamide acts as an inhibitor of acyl-CoA : cholesterol acyltransferase enzyme

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    71. Aggarwal, VK; Bethel, PA; Giles, R
      A formal synthesis of (+)-pyripyropene A using a biomimetic epoxy-olefin cyclisation

      CHEMICAL COMMUNICATIONS
    72. Rodriguez, A; Bachorik, PS; Wee, SB
      Navel effects of the acyl-coenzyme A : cholesterol acyltransferase inhibitor 58-035 on foam cell development in primary human monocyte-derived macrophages

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    73. Blans, P; Vigroux, A
      A general buffer-acid-catalyzed C-O cleavage reaction in the hydrolysis ofphenyl N-(phenoxycarbonyl)sulfamate ester

      CHEMISTRY-A EUROPEAN JOURNAL
    74. Lutton, C
      The genetically hypercholesterolemic RICO rat: a good model for testing a food substance or a drug specific for a key enzyme involved in cholesterol metabolism?

      REPRODUCTION NUTRITION DEVELOPMENT
    75. Bosner, MS; Wolff, AA; Ostlund, RE
      Lack of effect of cholesterol esterase inhibitor CVT-1 on cholesterol absorption and LDL cholesterol in humans

      CARDIOVASCULAR DRUGS AND THERAPY
    76. Shin, YW; Bok, SH; Jeong, TS; Bae, KH; Jeoung, NH; Choi, MS; Lee, SH; Park, YB
      Hypocholesterolemic effect of naringin associated with hepatic cholesterolregulating enzyme changes in rats

      INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH
    77. Aggarwal, VK; Bethel, PA; Giles, R
      A formal synthesis of (+)-pyripyropene A using a biomimetic epoxy-olefin cyclisation: effect of epoxy alcohol/ether on cyclisation efficiency

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    78. Lee, SH; Jeong, TS; Park, YB; Kwon, YK; Choi, MS; Bok, SH
      Hypocholesterolemic effect of hesperetin mediated by inhibition of 3-hydroxy-3-methylgultaryl coenzyme a reductase and acyl coenzyme A: Cholesterol acyltransferase in rats fed high-cholesterol diet

      NUTRITION RESEARCH
    79. Post, SM; Zoeteweij, JP; Bos, MHA; de Wit, ECM; Havinga, R; Kuipers, F; Princen, HMG
      Acyl-coenzyme A : cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7 alpha-hydroxylase in cultured rat hepatocytes and in vivo in the rat

      HEPATOLOGY
    80. Lee, SH; Park, YB; Bae, KH; Bok, SH; Kwon, YK; Lee, ES; Choi, MS
      Cholesterol-lowering activity of naringenin via inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase and acyl coenzyme A : cholesterol acyltransferase in rats

      ANNALS OF NUTRITION AND METABOLISM
    81. Douglas, CJ; Sklenicka, HM; Shen, HC; Mathias, DS; Degen, SJ; Golding, GM; Morgan, CD; Shih, RA; Mueller, KL; Seurer, LM; Johnson, EW; Hsung, RP
      Synthesis and UV studies of a small library of 6-aryl-4-hydroxy-2-pyrones.A relevant structural feature for the inhibitory property of arisugacin against acetylcholinesterase.

      TETRAHEDRON
    82. Romeo, G; Salerno, L; Milla, P; Siracusa, M; Cattel, L; Russo, F
      Synthesis of novel 4,5-diphenylthiazole derivatives as potential acyl-CoA : cholesterol O-acyltransferase inhibitors

      PHARMAZIE
    83. Bok, SH; Lee, SH; Park, YB; Bae, KH; Son, KH; Jeong, TS; Choi, MS
      Plasma and hepatic cholesterol and hepatic activities of 3-hydroxy-3-methyl-glutaryl-CoA reductase and acyl CoA: Cholesterol transferase are lower inrats fed citrus peel extract or a mixture of citrus bioflavonoids

      JOURNAL OF NUTRITION
    84. Burnett, JR; Wilcox, LJ; Telford, DE; Kleinstiver, SJ; Barrett, PHR; Newton, RS; Huff, MW
      Inhibition of ACAT by avasimibe decreases both VLDL and LDL apolipoproteinB production in miniature pigs

      JOURNAL OF LIPID RESEARCH
    85. Whitman, SC; Argmann, CA; Sawyez, CG; Miller, DB; Hegele, RA; Huff, MW
      Uptake of type IV hypertriglyceridemic VLDL by cultured macrophages is enhanced by interferon-gamma

      JOURNAL OF LIPID RESEARCH
    86. Escary, JL; Choy, HA; Reue, K; Wang, XP; Castellani, LW; Glass, CK; Lusis, AJ; Schotz, MC
      Paradoxical effect on atherosclerosis of hormone-sensitive lipase overexpression in macrophages

      JOURNAL OF LIPID RESEARCH
    87. Sparrow, CP; Patel, S; Baffic, J; Chao, YS; Hernandez, M; Lam, MH; Montenegro, J; Wright, SD; Detmers, PA
      A fluorescent cholesterol analog traces cholesterol absorption in hamstersand is esterified in vivo and in vitro

      JOURNAL OF LIPID RESEARCH
    88. Lin, S; Cheng, D; Liu, MS; Chen, J; Chang, TY
      Human Acyl-CoA : Cholesterol acyltransferase-1 in the endoplasmic reticulum contains seven transmembrane domains

      JOURNAL OF BIOLOGICAL CHEMISTRY
    89. Namatame, I; Tomoda, H; Arai, H; Inoue, K; Omura, S
      Complete inhibition of mouse macrophage-derived foam cell formation by triacsin C

      JOURNAL OF BIOCHEMISTRY
    90. Asami, Y; Yamagishi, I; Akiyoshi, K; Tomoike, H; Tsuchida, K; Higuchi, S
      Inhibitory effect of TS-962 on the formation of early atherosclerotic lesions in high fat-fed hyperlipidemic hamsters

      ATHEROSCLEROSIS
    91. Azuma, Y; Seto, J; Ohno, K; Mikami, H; Yamada, T; Yamasaki, M; Chiba, M; Nobuhara, Y
      Effects of NTE-122, an acyl-CoA : cholesterol acyltransferase inhibitor, on cholesterol esterification and lipid secretion from CaCo-2 cells, and cholesterol absorption in rats

      JAPANESE JOURNAL OF PHARMACOLOGY
    92. Azuma, Y; Kawasaki, T; Ohno, K; Seto, J; Yamada, T; Yamasaki, M; Nobuhara, Y
      Effects of NTE-122, a novel acyl-CoA : cholesterol acyltransferase inhibitor, on cholesterol esterification and secretions of apolipoprotein B-containing lipoprotein and bile acids in HepG2

      JAPANESE JOURNAL OF PHARMACOLOGY
    93. Azuma, Y; Kawasaki, T; Ikemoto, K; Ohno, K; Yamada, T; Yamasaki, M; Nobuhara, Y
      Effects of NTE-122, a novel acyl-CoA : cholesterol acyltransferase inhibitor, on cholesterol esterification and high-density lipoprotein-induced cholesterol efflux in macrophages

      JAPANESE JOURNAL OF PHARMACOLOGY
    94. Burnett, JR; Wilcox, LJ; Huff, MW
      Acyl coenzyme A: cholesterol acyltransferase inhibition and hepatic apolipoprotein B secretion

      CLINICA CHIMICA ACTA
    95. Conde, K; Pineda, G; Newton, RS; Fernandez, ML
      Hypocholesterolemic effects of 3-hydroxy-3-methylglutaryl coenzyme a (HMG-CoA) reductase inhibitors in the guinea - Atorvastatin versus simvastatin

      BIOCHEMICAL PHARMACOLOGY
    96. ROTH BD
      ACAT INHIBITORS - EVOLUTION FROM CHOLESTEROL-ABSORPTION INHIBITORS TOANTIATHEROSCLEROTIC AGENTS

      Drug discovery today
    97. Sellers, T; O'Brien, S; Gossett, K; Gunning, M; Boram, D; Rehm, S; Kerns, W
      Altered hemostasis in male rats following administration of the ACAT inhibitor SKF-99085

      TOXICOLOGICAL SCIENCES
    98. MIYAZAKI A; SAKASHITA N; LEE O; TAKAHASHI K; HORIUCHI S; HAKAMATA H; MORGANELLI PM; CHANG CCY; CHANG TY
      EXPRESSION OF ACAT-1 PROTEIN IN HUMAN ATHEROSCLEROTIC LESIONS AND CULTURED HUMAN MONOCYTES-MACROPHAGES

      Arteriosclerosis, thrombosis, and vascular biology
    99. TANAKA A; TERASAWA T; HAGIHARA H; SAKUMA Y; ISHIBE N; SAWADA M; TAKASUGI H; TANAKA H
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ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/05/20 alle ore 19:58:47