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Synergism between base excision repair, mediated by the DNA glycosylases Ntg1 and Ntg2, and nucleotide excision repair in the removal of oxidatively damaged DNA bases in Saccharomyces cerevisiae
MOLECULAR GENETICS AND GENOMICS
High frequency of constitutive alkali-labile sites in mouse major satellite DNA, detected by DNA breakage detection-fluorescence in situ hybridization
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Excision repair of adozelesin-N3 adenine adduct by 3-methyladenine-DNA glycosylases and UVrABC nuclease
MOLECULES AND CELLS
Mutagenesis in eukaryotes dependent on DNA polymerase zeta and Rev1p
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene
ONCOGENE
Highly efficient synthesis of peptide-oligonucleotide conjugates: Chemoselective oxime and thiazolidine formation
CHEMISTRY-A EUROPEAN JOURNAL
Synthesis and testing of a novel fluorescence label for carbonyls in carbohydrates and cellulosics
SYNLETT
Frequencies and relative levels of clustered damages in DNA exposed to gamma rays in radioquenching vs. nonradioquenching conditions
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
DND repair and aging in mouse liver: 8-oxodG glycosylase activity increasein mitochondrial but not in nuclear extracts
FREE RADICAL BIOLOGY AND MEDICINE
Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass ofabasic sites
GENES & DEVELOPMENT
Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants
NUCLEIC ACIDS RESEARCH
A thermostable endonuclease III homolog from the archaeon Pyrobaculum aerophilum
NUCLEIC ACIDS RESEARCH
Enhanced activity of adenine-DNA glycosylase (Myh) by apurinic/apyrimidinic endonuclease (Ape1) in mammalian base excision repair of an A/GO mismatch
NUCLEIC ACIDS RESEARCH
Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair
NUCLEIC ACIDS RESEARCH
Translesional synthesis on DNA templates containing the 2 '-deoxyribonolactone lesion
NUCLEIC ACIDS RESEARCH
Human APES protein is mostly localized in the nuclei and to some extent inthe mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen
NUCLEIC ACIDS RESEARCH
Eukaryotic mutagenesis and translesion replication dependent on DNA polymerase zeta and Rev 1 protein
BIOCHEMICAL SOCIETY TRANSACTIONS
Pir1p mediates translocation of the yeast Apn1p endonuclease into the mitochondria to maintain genomic stability
MOLECULAR AND CELLULAR BIOLOGY
Securing genome stability by orchestrating DNA repair: removal of radiation-induced clustered lesions in DNA
BIOESSAYS
XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions
EMBO JOURNAL
Endogenous DNA damage and mutation
TRENDS IN GENETICS
Yeast base excision repair: Interconnections and networks
PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 68
Enzymology of mitochondrial base excision repair
PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 68
Properties and functions of human Uracil-DNA glycosylase from the UNG gene
PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 68
Synthesis of (S)-(+)-2-amino-6-(aminooxy)-hexanoic acid
SYNTHETIC COMMUNICATIONS
Response of base excision repair enzymes to complex DNA lesions
RADIATION RESEARCH
Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: Implications for the catalytic mechanism
JOURNAL OF MOLECULAR BIOLOGY
Base excision repair intermediates as topoisomerase II poisons
JOURNAL OF BIOLOGICAL CHEMISTRY
Conversion of the bifunctional 8-oxoguanine/beta-delta apurinic/apyrimidinic DNA repair activities of Drosophila ribosomal protein S3 into the human S3 monofunctional P-elimination catalyst through a single amino acid change
JOURNAL OF BIOLOGICAL CHEMISTRY
Overexpression of type I topoisomerases sensitizes yeast cells to DNA damage
JOURNAL OF BIOLOGICAL CHEMISTRY
Mutagenic properties of estrogen quinone-derived DNA adducts in simian kidney cells
BIOCHEMISTRY
Coupling of substrate recognition and catalysis by a human base-excision DNA repair protein
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
The 2-deoxyribonolactone lesion produced in DNA by neocarzinostatin and other damaging agents forms cross-links with the base-excision repair enzyme endonuclease III
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Evidence that error-prone DNA repair converts dibenzo[a, l]pyrene-induced depurinating lesions into mutations: formation, clonal proliferation and regression of initiated cells carrying H-ras oncogene mutations in early preneoplasia
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Passing the baton in base excision repair
NATURE STRUCTURAL BIOLOGY
DNA strand-break yields after post-irradiation incubation with base excision repair endonucleases implicate hydroxyl radical pairs in double-strand break formation
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
Reduced ligation during DNA base excision repair supported by BRCA2 mutantcells
ONCOGENE
Lessons learned from structural results on uracil-DNA glycosylase
MUTATION RESEARCH-DNA REPAIR
Abasic site recognition by two apurinic/apyrimidinic endonuclease familiesin DNA base excision repair: the 3 ' ends justify the means
MUTATION RESEARCH-DNA REPAIR
AP lyases and dRPases: commonality of mechanism
MUTATION RESEARCH-DNA REPAIR
Adaptation to alkylation damage in DNA measured by the comet assay
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
Mechanisms of DNA cleavage by copper complexes of 3-Clip-Phen and of its conjugate with a distamycin analogue
NUCLEIC ACIDS RESEARCH
Error-prone lesion bypass by human DNA polymerase eta
NUCLEIC ACIDS RESEARCH
NMR structure of a DNA duplex containing nucleoside analog 1-(2 '-deoxy-beta-D-ribofuranosyl)-3-nitropyrrole and the structure of the unmodified control
NUCLEIC ACIDS RESEARCH
Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro
NUCLEIC ACIDS RESEARCH
In vivo repair of methylation damage in Aag 3-methyladenine DNA glycosylase null mouse cells
NUCLEIC ACIDS RESEARCH
Modified alkaline elution allows the measurement of intact apurinic sites in mammalian genomic DNA
BIOCHIMIE
Characterization of class II apurinic/apyrimidinic endonuclease activitiesin the human malaria parasite, Plasmodium falciparum
BIOCHEMICAL JOURNAL
An express method of testing activity of a repair enzyme, uracil-DNA-glycosylase
BIOORGANICHESKAYA KHIMIYA
Base removers and strand scissors: Different strategies employed in base excision and strand incision at modified base residues in DNA
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
O-(acridinium)hydroxylamine (AHA): a reagent for the preparation of chemiluminescent acridinium oxime (AO)-steroid conjugates
STEROIDS
Uracil-DNA glycosylase-DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Induction of oxidative DNA damage in the peri-infarct region after permanent focal cerebral ischemia
JOURNAL OF NEUROCHEMISTRY
Distinct repair activities of human 7,8-dihydro-8 oxoguanine DNA glycosylase and formamidopyrimidine DNA glycosylase for formamidopyrimidine and 7,8-dihydro-8-oxoguanine
JOURNAL OF BIOLOGICAL CHEMISTRY
Protection against methylation-induced cytotoxicity by DNA polymerase beta-dependent long patch base excision repair
JOURNAL OF BIOLOGICAL CHEMISTRY
Characterization of a catalytically slow AP lyase activity in DNA polymerase gamma and other family A DNA polymerases
JOURNAL OF BIOLOGICAL CHEMISTRY
Overexpression of enzymes that repair endogenous damage to DNA
EUROPEAN JOURNAL OF BIOCHEMISTRY
Efficient DNA base excision repair in ataxia telangiectasia cells
EUROPEAN JOURNAL OF BIOCHEMISTRY
Highly selective isolation of unknown mutations in diverse DNA fragments: Toward new multiplex screening in cancer
CANCER RESEARCH
Substrate specificity of human methylpurine DNA N-glycosylase
BIOCHEMISTRY
Clustered damages and total lesions induced in DNA by ionizing radiation: Oxidized bases and strand breaks
BIOCHEMISTRY
Base excision repair is impaired in mammalian cells lacking poly(ADP-ribose) polymerase-1
BIOCHEMISTRY
Translesion replication by DNA polymerase delta depends on processivity accessory proteins and differs in specificity from DNA polymerase beta
BIOCHEMISTRY
Strand cleavage of supercoiled DNA by water-soluble peroxyl radicals. the overlooked importance of peroxyl radical charge
BIOCHEMISTRY
Polymerase dependence of autosticky polymerase chain reaction
ANALYTICAL BIOCHEMISTRY
Single-stranded oligodeoxyribonucleotides are substrates of Fpg protein from Escherichia coli
IUBMB LIFE
Aminooxy functionalized oligonucleotides: Preparation, on-support derivatization, and postsynthetic attachment to polymer support
BIOCONJUGATE CHEMISTRY
Novel artificial endonucleases inhibit base excision repair and potentiatethe cytotoxicity of DNA-damaging agents on L1210 cells
ANTI-CANCER DRUGS
Fluorescent labelling of closely-spaced aldehydes induced in DNA by bleomycin-Fe(III)
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
Age-independency of AP site incision capacity in women
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
Structural requirements of double and single stranded DNA substrates and inhibitors, including a photoaffinity label, of Fpg protein from Escherichiacoli
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
Novel non-isotopic detection of MutY enzyme-recognized mismatches in DNA via ultrasensitive detection of aldehydes
NUCLEIC ACIDS RESEARCH
Gene targeted DNA double-strand break induction by I-125-labeled tripler-forming oligonucleotides is highly mutagenic following repair in human cells
NUCLEIC ACIDS RESEARCH
The reactivity of the 2-deoxyribonolactone lesion in single-stranded DNA and its implication in reaction mechanisms of DNA damage and repair
NUCLEIC ACIDS RESEARCH
Differential subcellular localization of human MutY homolog (hMYH) and thefunctional activity of adenine : 8-oxoguanine DNA glycosylase
NUCLEIC ACIDS RESEARCH
The Saccharomyces cerevisiae ETH1 gene, an inducible homolog of exonuclease III that provides resistance to DNA-damaging agents and limits spontaneous mutagenesis
MOLECULAR AND CELLULAR BIOLOGY
Nucleotide excision repair modulates the cytotoxic and mutagenic effects of N-n-butyl-N-nitrosourea in cultured mammalian cells as well as in mouse splenocytes in vivo
MUTAGENESIS
Mutations at G : C base pairs predominate after replication of peroxyl radical-damaged pSP189 plasmids in human cells
MUTAGENESIS
Mapping of eukaryotic DNA topoisomerase I catalyzed cleavage without concomitant religation in the vicinity of DNA structural anomalies
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
Initiation of base excision repair: Glycosylase mechanisms and structures
ANNUAL REVIEW OF BIOCHEMISTRY
In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites
JOURNAL OF MOLECULAR BIOLOGY
Intragenic suppression of an active site mutation in the human apurinic/apyrimidinic endonuclease
JOURNAL OF MOLECULAR BIOLOGY
Cytosine arabinoside lesions are position-specific topoisomerase II poisons and stimulate DNA cleavage mediated by the human type II enzymes
JOURNAL OF BIOLOGICAL CHEMISTRY
The type of DNA glycosylase determines the base excision repair pathway inmammalian cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages - 7,8-dihydro-8-oxoguanine and 5-hydroxycytosine
JOURNAL OF BIOLOGICAL CHEMISTRY
The DNA helicases acting in nucleotide excision repair, XPD, CSB and XPB, are not required for PCNA-dependent repair of abasic sites
EUROPEAN JOURNAL OF BIOCHEMISTRY
Mechanistic studies on the base-catalyzed transformation of neocarzinostatin chromophore: Roles of bulged DNA
BIOCHEMISTRY
2 '-deoxyribonolactone lesion in DNA: Refined solution structure determined by nuclear magnetic resonance and molecular modeling
BIOCHEMISTRY
Characterization of amino acid substitutions that severely alter the DNA repair functions of Escherichia coli endonuclease IV
BIOCHEMISTRY
STRUCTURE-FUNCTION-RELATIONSHIPS IN THE HAMMERHEAD RIBOZYME PROBED BYBASE RESCUE
RNA
STRUCTURE OF A DNA BASE-EXCISION PRODUCT RESEMBLING A CISPLATIN INTER-STRAND ADDUCT
Nature structural biology
O-(fluoresceinylmethyl)hydroxylamine (OFMHA): A fluorescent reagent for detection of damaged nucleic acids
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
MUTANT AP ENDONUCLEASE IN PATIENTS WITH AMYOTROPHIC-LATERAL-SCLEROSIS
NeuroReport
MAMMALIAN BASE EXCISION-REPAIR BY DNA-POLYMERASE-DELTA AND DNA-POLYMERASE-EPSILON
Oncogene
Induction of fragile sites by fluorodeoxyuridine and caffeine accompanies with misincorpolation of endogenous uridine nucleotide into DNA of feline fibroblasts
JOURNAL OF VETERINARY MEDICAL SCIENCE
INVESTIGATING NUCLEIC-ACID DAMAGE PROCESSES VIA INDEPENDENT GENERATION OF REACTIVE INTERMEDIATES
Chemical research in toxicology
EXONUCLEASE-IX OF ESCHERICHIA-COLI
Nucleic acids research
AP ENDONUCLEASE ACTIVITY IN HUMANS - DEVELOPMENT OF A SIMPLE ASSAY AND ANALYSIS OF 10 NORMAL INDIVIDUALS
Teratogenesis, carcinogenesis, and mutagenesis