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La ricerca find articoli where soggetti phrase all words '3''-AZIDO-3''-DEOXYTHYMIDINE' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 575 riferimenti
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    1. Freund, YR; Dousman, L; Riccio, ES; Sato, B; MacGregor, JT; Mohagheghpour, N
      Immunohematotoxicity studies with combinations of dapsone and zidovudine

      INTERNATIONAL IMMUNOPHARMACOLOGY
    2. Olivero, OA; Reddy, MK; Pietras, SM; Poirier, MC
      Plasma drug levels compared with DNA incorporation of 3'-azido-3'-deoxythymidine (AZT) in adult cynomolgus (Macaca fascicularis) monkeys

      EXPERIMENTAL BIOLOGY AND MEDICINE
    3. Akeb, F; Creminon, C; Grassi, J; Guedj, R; Duval, D
      The production and evaluation of antibodies for enzyme immunoassay of AZTTP

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    4. Pancaldi, S; Bonora, A; Baldisserotto, C; Gualandri, R; Neri, LM; Fasulo, MP
      Deregulation of light-induced plastidogenesis in etiolated Euglena gracilis klebs treated with DNA hypermethylating 3 '-azido-3 '-deoxythymidine

      PLANT BIOLOGY
    5. Miller, V; Larder, BA
      Mutational patterns in the HIV genome and cross-resistance following nucleoside and nucleotide analogue drug exposure

      ANTIVIRAL THERAPY
    6. D'Andrea, G; Di Ciccio, L; Brisdelli, F; D'Alessandro, AM; Bozzi, A; Oratore, A
      Purification and partial characterization of an alpha-2,8-sialyltransferase from human erythroleukemia K562 cells

      PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY
    7. Malin, AA; Ostrovskii, VA
      Synthesis of thymidine derivatives as potential pharmaceuticals against HIV/AIDS infection

      RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
    8. White, JD; Wharfe, G; Stewart, DM; Maher, VE; Eicher, D; Herring, B; Derby, M; Jackson-Booth, PG; Marshall, M; Lucy, D; Jain, A; Cranston, B; Hanchard, B; Lee, CC; Top, LE; Fleisher, TA; Nelson, DL; Waldmann, TA
      The combination of zidovudine and interferon alpha-2B in the treatment of adult T-cell leukemia/lymphoma

      LEUKEMIA & LYMPHOMA
    9. Habib, EE; Yokomizo, K; Nagao, K; Harada, S; Uyeda, M
      Antiviral activity of fattiviracin FV-8 against human immunodeficiency virus type 1 (HIV-1)

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    10. Kim, EY; Vrang, L; Oberg, B; Merigan, TC
      Anti-HIV type 1 activity of 3 '-fluoro-3 '-deoxythymidine for several different multidrug-resistant mutants

      AIDS RESEARCH AND HUMAN RETROVIRUSES
    11. Dembri, A; Montisci, MJ; Gantier, JC; Chacun, H; Ponchel, G
      Targeting of 3 '-azido 3 '-deoxythymidine (AZT)-loaded poly(isohexylcyanoacrylate) nanospheres to the gastrointestinal mucosa and associated lymphoidtissues

      PHARMACEUTICAL RESEARCH
    12. Yamaguchi, K; Ushijima, H; Hisano, M; Inoue, Y; Shimamura, T; Hirano, T; Muller, WEG
      Immunomodulatory effect of gold sodium thiomalate on murine acquired immunodeficiency syndrome

      MICROBIOLOGY AND IMMUNOLOGY
    13. Mehnert, W; Mader, K
      Solid lipid nanoparticles - Production, characterization and applications

      ADVANCED DRUG DELIVERY REVIEWS
    14. Tejera, AM; Alonso, DF; Gomez, DE; Olivero, OA
      Chronic in vitro exposure to 3 '-azido-2 ', 3 '-dideoxythymidine induces senescence and apoptosis and reduces tumorigenicity of metastatic mouse mammary tumor cells

      BREAST CANCER RESEARCH AND TREATMENT
    15. Kucera, GL; Goff, CL; Iyer, N; Morris-Natschke, S; Ishaq, KS; Wyrick, SD; Fleming, RA; Kucera, LS
      Cellular metabolism in lymphocytes of a novel thioether-phospholipid-AZT conjugate with anti-HIV-1 activity

      ANTIVIRAL RESEARCH
    16. Sharmeen, L; McQuade, T; Heldsinger, A; Gogliotti, R; Domagala, J; Gracheck, S
      Inhibition of the early phase of HIV replication by an isothiazolone, PD 161374

      ANTIVIRAL RESEARCH
    17. Lake-Bakaar, G; Mazzoccoli, V; Dickman, K; Lyubsky, S
      Differential effects of nucleoside analogs on oxidative phosphorylation inhuman pancreatic cells

      DIGESTIVE DISEASES AND SCIENCES
    18. Fratianni, A; Pastore, D; Pallotta, ML; Chiatante, D; Passarella, S
      Increase of membrane permeability of mitochondria isolated from water stress adapted potato cells

      BIOSCIENCE REPORTS
    19. Lennerstrand, J; Stammers, DK; Larder, BA
      Biochemical mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to stavudine

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    20. Hammond, JL; Koontz, DL; Bazmi, HZ; Beadle, JR; Hostetler, SE; Kini, GD; Aldern, KA; Richman, DD; Hostetler, KY; Mellors, JW
      Alkylglycerol prodrugs of phosphonoformate are potent in vitro inhibitors of nucleoside-resistant human immunodeficiency virus type 1 and select for resistance mutations that suppress zidovudine resistance

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    21. Hoggard, PG; Sales, SD; Phiboonbanakit, D; Lloyd, J; Maher, BA; Khoo, SH; Wilkins, E; Carey, P; Hart, CA; Back, DJ
      Influence of prior exposure to zidovudine on stavudine phosphorylation in vivo and ex vivo

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    22. Tenser, RB; Gaydos, A; Hay, KA
      Inhibition of herpes simplex virus reactivation by dipyridamole

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    23. Sales, SD; Hoggard, PG; Sunderland, D; Khoo, S; Hart, CA; Back, DJ
      Zidovudine phosphorylation and mitochondrial toxicity in vitro

      TOXICOLOGY AND APPLIED PHARMACOLOGY
    24. Gauthier, C; Ramondenc, Y; Ple, G
      A novel synthesis of AZT

      TETRAHEDRON
    25. Aruna, R; Jagetia, GC
      Azidothymidine induces dose dependent increase in micronuclei formation incultured HeLa cells

      PHARMAZIE
    26. Louat, T; Servant, L; Rols, MP; Bieth, A; Teissie, J; Hoffmann, JS; Cazaux, C
      Antitumor activity of 2 ',3 '-dideoxycytidine nucleotide analog against tumors up-regulating DNA polymerase beta

      MOLECULAR PHARMACOLOGY
    27. Lewis, W; Haase, CP; Raidel, SM; Russ, RB; Sutliff, RL; Hoit, BD; Samarel, AM
      Combined antiretroviral therapy causes cardiomyopathy and elevates plasma lactate in transgenic AIDS mice

      LABORATORY INVESTIGATION
    28. Lennerstrand, J; Hertogs, K; Stammers, DK; Larder, BA
      Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type1 mutants

      JOURNAL OF VIROLOGY
    29. Boyer, PL; Sarafianos, SG; Arnold, E; Hughes, SH
      Selective excision of AZTMP by drug-resistant human immunodeficiency virusreverse transcriptase

      JOURNAL OF VIROLOGY
    30. Mavromoustakos, T; Calogeropoulou, T; Koufaki, M; Kolocouris, A; Daliani, I; Demetzos, C; Meng, ZX; Makriyannis, A; Balzarini, J; De Clercq, E
      Ether phospholipid-AZT conjugates possessing anti-HIV and antitumor cell activity. Synthesis, conformational analysis, and study of their thermal effects on membrane bilayers

      JOURNAL OF MEDICINAL CHEMISTRY
    31. Selmi, B; Boretto, J; Navarro, JM; Sire, J; Longhi, S; Guerreiro, C; Mulard, L; Sarfati, S; Canard, B
      The valine-to-threonine 75 substitution in human immunodeficiency virus type 1 reverse transcriptase and its relation with stavudine resistance

      JOURNAL OF BIOLOGICAL CHEMISTRY
    32. Leung, S; Bendayan, R
      Uptake properties of lamivudine (3TC) by a continuous renal epithelial cell line

      CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
    33. D'Cruz, OJ; Venkatachalam, TK; Uckun, FM
      Thymidine kinase-independent intracellular delivery of bioactive nucleotides by aryl phosphate derivatives of bromo-methoxy zidovudine (compounds WHI-05 and WHI-07) in normal human female genital tract epithelial cells and sperm

      BIOLOGY OF REPRODUCTION
    34. Stevenson, MAM; McBroom, DG
      In vitro characterization of FIV-pPPR, a pathogenic molecular clone of feline immunodeficiency virus, and two drug-resistant pol gene mutants

      AMERICAN JOURNAL OF VETERINARY RESEARCH
    35. Mourier, N; Camplo, M; Della Bruna, GS; Pellacini, F; Ungheri, D; Chermann, JC; Kraus, JL
      Synthesis and anti-HIV evaluation of new 2 ',3 '-dideoxy-3 '-thiacytidine prodrugs

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    36. Parker, WB; Shaddix, SC; Rose, LM; Pham, PT; Hua, M; Vince, R
      Metabolism of O-6-propyl and N-6-propyl-carbovir in CEM cells

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    37. Chang, SL; Griesgraber, G; Abraham, TW; Garg, T; Song, H; Zimmerman, CL; Wagner, CR
      Synthesis and antiviral activity of amino acid carbamate derivatives of AZT

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    38. Robbins, BL; Greenshaw, J; Fridland, A
      Cellular phosphorylation of 2 ',3 '-dideoxyadenosine-5 '-monophosphate, a key intermediate in the activation of the antiviral agent DDI, in huhlan peripheral blood mononuclear cells

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    39. Girard, PM; Pegram, PS; Diquet, B; Anderson, R; Raffi, F; Tubiana, R; Sereni, D; Boerner, D
      Phase II placebo-controlled trial of fozivudine tidoxil for HIV infection:Pharmacokinetics, tolerability, and efficacy

      JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
    40. Sluis-Cremer, N; Arion, D; Parniak, MA
      Molecular mechanisms of HIV-1 resistance to nucleoside reverse transcriptase inhibitors (NRTIs)

      CELLULAR AND MOLECULAR LIFE SCIENCES
    41. Furman, PA; Painter, GR; Anderson, KS
      An analysis of the catalytic cycle of HIV-1 reverse transcriptase: Opportunities for chemotherapeutic intervention based on enzyme inhibition

      CURRENT PHARMACEUTICAL DESIGN
    42. Gotte, M; Wainberg, MA
      Biochemical mechanisms involved in overcoming HIV resistance to nucleosideinhibitors of reverse transcriptase

      DRUG RESISTANCE UPDATES
    43. Valenti, D; Barile, M; Passarella, S
      AZT inhibition of the ADP/ATP antiport in isolated rat heart mitochondria

      INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
    44. Meng, QX; Su, T; Olivero, OA; Poirier, MC; Shi, XC; Ding, XX; Walker, VE
      Relationships between DNA incorporation, mutant frequency, and loss of heterozygosity at the TK locus in human lymphoblastoid cells exposed to 3 '-azido-3 '-deoxythymidine

      TOXICOLOGICAL SCIENCES
    45. Akeb, F; Duval, D; Guedj, R
      Design and synthesis of nucleoside phosphate mono(aminoalkyl)ester

      PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
    46. Hoggard, PG; Sales, SD; Kewn, S; Sunderland, D; Khoo, SH; Hart, CA; Back, DJ
      Correlation between intracellular pharmacological activation of nucleosideanalogues and HIV suppression in vitro

      ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
    47. Mediavilla, MD; Sanchez-Barcelo, EJ
      Doses and time-dependent effects of 3 :-azido-3 '-deoxythymidine on T47D human breast cancer cells in vitro

      PHARMACOLOGY & TOXICOLOGY
    48. Becker, B
      Anionic conjugate addition reactions for the preparation of substituted monosaccharides and disaccharides

      JOURNAL OF CARBOHYDRATE CHEMISTRY
    49. Jin, Y; Seki, T; Morimoto, Y; Juni, K
      Effect of application volume of ethanol-isopropyl myristate mixed solvent system on permeation of zidovudine and probenecid through rat skin

      DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
    50. Fang, JL; Beland, FA
      Development of a novel P-32-postlabeling method for the analysis of 3 '-azido-3 '-deoxythymidine

      CANCER LETTERS
    51. Mas, A; Parera, M; Briones, C; Soriano, V; Martinez, MA; Domingo, E; Menendez-Arias, L
      Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance

      EMBO JOURNAL
    52. Meyer, P; Schneider, B; Sarfati, S; Deville-Bonne, D; Guerreiro, C; Boretto, J; Janin, J; Veron, M; Canard, B
      Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase

      EMBO JOURNAL
    53. Francke, S; Orosz, CG; Hayes, KA; Mathes, LE
      Effect of zidovudine on the primary cytolytic T-lymphocyte response and T-cell effector function

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    54. Wattanagoon, Y; Bangchang, KN; Hoggard, PG; Khoo, SH; Gibbons, SE; Phiboonbhanakit, D; Karbwang, J; Back, DJ
      Pharmacokinetics of zidovudine phosphorylation in human immunodeficiency virus-positive Thai patients and healthy volunteers

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    55. Richard, N; Salomon, H; Rando, R; Mansour, T; Bowlin, TL; Wainberg, MA
      Selection and characterization of human immunodeficiency virus type 1 variants resistant to the (+) and (-) enantiomers of 2 '-deoxy-3 '-oxa-4 '-thio-5-fluorocytidine

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    56. Pan-Zhou, XR; Cui, LX; Zhou, XJ; Sommadossi, JP; Darley-Usmar, VM
      Differential effects of antiretroviral nucleoside analogs on mitochondrialfunction in HepG2 cells

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    57. Rodriguez, JF; Rodriguez, JL; Santana, J; Garcia, H; Rosario, O
      Simultaneous quantitation of intracellular zidovudine and lamivudine triphosphates in human immunodeficiency virus-infected individuals

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    58. Baraniak, J; Kaczmarek, R; Stec, WJ
      Conjugation of amino acid O-methyl esters with AZT-5 '-O-phosphorothioate and phosphorodithioate

      TETRAHEDRON LETTERS
    59. Patterson, TA; Binienda, ZK; Newport, GD; Lipe, GW; Gillam, MP; Slikker, W; Sandberg, JK
      Transplacental pharmacokinetics and fetal distribution of 2 ',3 '-didehydro-3 '-deoxythymidine (d4T) and its metabolites in late-term rhesus macaques

      TERATOLOGY
    60. Meng, QX; Walker, DM; Olivero, OA; Shi, XC; Antiochos, BB; Poirier, MC; Walker, VE
      Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    61. Gotte, M; Arion, D; Parniak, MA; Wainberg, MA
      The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis

      JOURNAL OF VIROLOGY
    62. Sato, H; Tomita, Y; Shibamura, K; Shiino, T; Miyakuni, T; Takebe, Y
      Convergent evolution of reverse transcriptase (RT) genes of human immunodeficiency virus type 1 subtypes E and B following nucleoside analogue RT inhibitor therapies

      JOURNAL OF VIROLOGY
    63. Radwan, MA
      Zidovudine, diclofenac and ketoprofen pharmacokinetic interactions in rats

      JOURNAL OF PHARMACY AND PHARMACOLOGY
    64. Takubo, T; Kato, T; Kinami, J; Hanada, K; Ogata, H
      Effect of lamivudine on uptake of organic cations by rat renal brush-border and basolateral membrane vesicles

      JOURNAL OF PHARMACY AND PHARMACOLOGY
    65. Kitazawa, T; Hosoya, K; Takahashi, T; Sugiyama, Y; Terasaki, T
      In-vivo and in-vitro evidence of a carrier-mediated efflux transport system for oestrone-3-sulphate across the blood-cerebrospinal fluid barrier

      JOURNAL OF PHARMACY AND PHARMACOLOGY
    66. Wada, S; Tsuda, M; Sekine, T; Cha, SH; Kimura, M; Kanai, Y; Endou, H
      Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    67. Ostermann, N; Lavie, A; Padiyar, S; Brundiers, R; Veit, T; Reinstein, J; Goody, RS; Konrad, M; Schlichting, I
      Potentiating AZT activation: Structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP

      JOURNAL OF MOLECULAR BIOLOGY
    68. Kalirai, SK; Scanlon, B; Taylor, SC; Ahmad, SI
      Screening of microbes, isolation, genetic manipulation, and physiological optimization of Brevibacterium helvolum to produce and excrete thymidine and deoxyuridine in high concentrations

      JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY
    69. Klarmann, GJ; Smith, RA; Schinazi, RF; North, TW; Preston, BD
      Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S - Template interactions influencesubstrate recognition at the polymerase active site

      JOURNAL OF BIOLOGICAL CHEMISTRY
    70. Macchia, M; Antonelli, G; Bertini, S; Calvani, F; Di Bussolo, V; Minutolo, F; Tesoro, R; Tonetti, I; Turriziani, O
      Synthesis and antiviral properties of novel analogues of monophosphate anddiphosphate bioactive forms of acyclovir

      FARMACO
    71. D'Alessandro, AM; Rinaldi, AC; D'Andrea, G; Brisdelli, F; Di Ciccio, L; Di Giulio, A; Oratore, A; Bozzi, A
      Evidences that zidovudine (AZT) could not be directly responsible for ironoverload in AZT-treated patients: an in vitro study

      CLINICA CHIMICA ACTA
    72. Chun, BK; Schinazi, RF; Cheng, YC; Chu, CK
      Synthesis of 2 ',3 '-dideoxy-3 '-fluoro-L-ribonucleosides as potential antiviral agents from D-sorbitol

      CARBOHYDRATE RESEARCH
    73. Lazaro, JB; Boretto, J; Selmi, B; Capony, JP; Canard, B
      Phosphorylation of AZT-resistant human immunodeficiency virus type 1 reverse transcriptase by casein kinase II in vitro: Effects on inhibitor sensitivity

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    74. Arion, D; Parniak, MA
      HIV resistance to zidovudine: the role of pyrophosphorolysis

      DRUG RESISTANCE UPDATES
    75. D'Cruz, OJ; Shih, MJ; Yiv, SH; Chen, CL; Uckun, FM
      Synthesis, characterization and preclinical formulation of a dual-action phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07) with potent anti-HIV and spermicidal activities

      MOLECULAR HUMAN REPRODUCTION
    76. Meyer, PR; Matsuura, SE; Mian, AM; So, AG; Scott, WA
      A mechanism of AZT resistance: An increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase

      MOLECULAR CELL
    77. Schuetz, JD; Connelly, MC; Sun, DX; Paibir, SG; Flynn, PM; Srinivas, RV; Kumar, A; Fridland, A
      MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs

      NATURE MEDICINE
    78. Delforge, ML; Farber, CM; De Leener, F; Caroyer, JM; Liesnard, C; Van Vooren, JP
      Foscarnet activity on human immunodeficiency virus type 1 in the central nervous system

      CLINICAL INFECTIOUS DISEASES
    79. Plessinger, MA; Miller, RK
      Effects of Zidovudine (AZT) and dideoxyinosine (ddI) on human trophoblast cells

      REPRODUCTIVE TOXICOLOGY
    80. Zheng, XP; Nair, V
      Homologues of isomeric dideoxynucleosides as potential antiviral agents: Synthesis of isodideoxynucleosides with a furanethanol sugar moiety

      NUCLEOSIDES & NUCLEOTIDES
    81. Motura, M; Salomon, H; Moroni, G; Wainberg, M; Brinon, MC
      Synthesis, lipophilicity and anti-HIV activity of a new brominated analog of zidovudine

      NUCLEOSIDES & NUCLEOTIDES
    82. Gallicano, KD; Sahai, J; Shukla, VK; Seguin, I; Pakuts, A; Kwok, D; Foster, BC; Cameron, DW
      Induction of zidovudine glucuronidation and amination pathways by rifampicin in HIV-infected patients

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    83. Steet, R; Alizadeh, M; Melancon, P; Kuchta, RD
      3 '-azidothymidine significantly alters glycosphingolipid synthesis in melanoma cells and decreases the shedding of gangliosides

      GLYCOCONJUGATE JOURNAL
    84. Olivero, OA; Shearer, GM; Chougnet, CA; Kovacs, AAS; Landay, AL; Baker, R; Stek, AM; Khoury, MM; Proia, LA; Kessler, HA; Sha, BE; Tarone, RE; Poirier, MC
      Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero

      AIDS
    85. Schott, H; Ludwig, PS; Immelmann, A; Schwendener, RA
      Synthesis and in vitro anti-HIV activities of amphiphilic heterodinucleoside phosphate derivatives containing the 2 ',3 '-dideoxynucleosides ddC, AZTand ddI

      EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
    86. Bowden, R; Tate, SM; Soto, S; Specter, S
      Alteration of cytokine levels in murine retrovirus infection: modulation by combination therapy

      INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY
    87. Sugiyama, Y; Kusuhara, H; Suzuki, H
      Kinetic and biochemical analysis of carrier-mediated efflux of drugs through the blood-brain and blood-cerebrospinal fluid barriers: importance in the drug delivery to the brain

      JOURNAL OF CONTROLLED RELEASE
    88. D'Alessandro, AM; D'Andrea, G; Di Ciccio, L; Brisdelli, F; Rinaldi, AC; Bozzi, A; Oratore, A
      3 '-Azido-3 '-deoxythymidine reduces the rate of transferrin receptor endocytosis in K562 cells

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
    89. Henderson, DK
      Postexposure chemoprophylaxis for occupational exposures to the human immunodeficiency virus

      JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
    90. Pless, D; Gouze, JN; Senay, C; Herber, R; Leroy, P; Barberousse, V; Fournel-Gigleux, S; Magdalou, J
      Characterization of the UDP-glucuronosyltransferases involved in the glucuronidation of an antithrombotic thioxyloside in rat and humans

      DRUG METABOLISM AND DISPOSITION
    91. de Muys, JM; Gourdeau, H; Nguyen-Ba, N; Taylor, DL; Ahmed, PS; Mansour, T; Locas, C; Richard, N; Wainberg, MA; Rando, RF
      Anti-human immunodeficiency virus type 1 activity, intracellular metabolism, and pharmacokinetic evaluation of 2 '-deoxy-3 '-oxa-4 '-thiocytidine

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    92. Palmer, S; Shafer, RW; Merigan, TC
      Hydroxyurea enhances the activities of didanosine, 9-[2(phosphonylmethoxy)ethyl] adenine, and 9-[2(phosphonylmethoxy)propyl]adenine against drug-susceptible and drug-resistant human immunodeficiency virus isolates

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    93. Balzarini, J; Naesens, L; Aquaro, S; Knispel, T; Perno, CF; De Clercq, E; Meier, C
      Intracellular metabolism of CycloSaligenyl 3 '-azido-2 ',3 '-dideoxythymidine monophosphate, a prodrug of 3 '-azido-2 ',3 '-dideoxythymidine (zidovudine)

      MOLECULAR PHARMACOLOGY
    94. Van Rompay, AR; Johansson, M; Karlsson, A
      Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: Molecular characterization of the human enzyme

      MOLECULAR PHARMACOLOGY
    95. Skoblov, YS; Frank-Kamenetskaya, MD; Chernov, DN
      Adenylate kinase from human placenta: Phosphorylation of modified nucleoside 5 '-phosphonates

      MOLECULAR BIOLOGY
    96. Taylor, GP; Hall, SE; Navarrete, S; Michie, CA; Davis, R; Witkover, AD; Rossor, M; Nowak, MA; Rudge, P; Matutes, E; Bangham, CRM; Weber, JN
      Effect of lamivudine on human T-cell leukemia virus type 1 (HTLV-1) DNA copy number, T-cell phenotype, and anti-tax cytotoxic T-cell frequency in patients with HTLV-1-associated myelopathy

      JOURNAL OF VIROLOGY
    97. Masini, A; Scotti, C; Calligaro, A; Cazzalini, O; Stivala, LA; Bianchi, L; Giovannini, F; Ceccarelli, D; Muscatello, U; Tomasi, A; Vannini, V
      Zidovudine-induced experimental myopathy: dual mechanism of mitochondrial damage

      JOURNAL OF THE NEUROLOGICAL SCIENCES
    98. Furlan, V; Demirdjian, S; Bourdon, O; Magdalou, J; Taburet, AM
      Glucuronidation of drugs by hepatic microsomes derived from healthy and cirrhotic human livers

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    99. Yazdanian, M
      Blood-brain barrier properties of human immunodeficiency virus antiretrovirals

      JOURNAL OF PHARMACEUTICAL SCIENCES
    100. Rodman, JH; Flynn, PM; Robbins, B; Jimenez, E; Bardeguez, AD; Rodriguez, JF; Blanchard, S; Fridland, A
      Systemic pharmacokinetics and cellular pharmacology of zidovudine in humanimmunodeficiency virus type 1-infected women and newborn infants

      JOURNAL OF INFECTIOUS DISEASES


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Documento generato il 20/10/20 alle ore 08:40:20