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1. Hoffmann, KF; McCarty, TC; Segal, DH; Chiaramonte, M; Hesse, M; Davis, EM; Cheever, AW; Meltzer, PS; Morse, HC; Wynn, TA
   Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type-1 and type-2 cytokine-mediated inflammatory reactions
   FASEB JOURNAL
   
   K.F. Hoffmann et al., "Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type-1 and type-2 cytokine-mediated inflammatory reactions", FASEB J, 15(11), 2001, pp. NIL_233-NIL_255
2. Chiaramonte, MG; Cheever, AW; Malley, JD; Donaldson, DD; Wynn, TA
   Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis
   HEPATOLOGY
   
   M.G. Chiaramonte et al., "Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis", HEPATOLOGY, 34(2), 2001, pp. 273-282
3. Hoffmann, KF; Davis, EM; Fischer, ER; Wynn, TA
   The guanine protein coupled receptor rhodopsin is developmentally regulated in the free-living stages of Schistosoma mansoni
   MOLECULAR AND BIOCHEMICAL PARASITOLOGY
   
   K.F. Hoffmann et al., "The guanine protein coupled receptor rhodopsin is developmentally regulated in the free-living stages of Schistosoma mansoni", MOL BIOCH P, 112(1), 2001, pp. 113-123
4. Vaillant, B; Chiaramonte, MG; Cheever, AW; Soloway, PD; Wynn, TA
   Regulation of hepatic fibrosis and extracellular matrix genes by the Th response: New insight into the role of tissue inhibitors of matrix metalloproteinases
   JOURNAL OF IMMUNOLOGY
   
   B. Vaillant et al., "Regulation of hepatic fibrosis and extracellular matrix genes by the Th response: New insight into the role of tissue inhibitors of matrix metalloproteinases", J IMMUNOL, 167(12), 2001, pp. 7017-7026
5. Hesse, M; Modolell, M; La Flamme, AC; Schito, M; Fuentes, JM; Cheever, AW; Pearce, EJ; Wynn, TA
   Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of L-arginine metabolism
   JOURNAL OF IMMUNOLOGY
   
   M. Hesse et al., "Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of L-arginine metabolism", J IMMUNOL, 167(11), 2001, pp. 6533-6544
6. Rutschman, R; Lang, R; Hesse, M; Ihle, JN; Wynn, TA; Murray, PJ
   Cutting edge: Stat6-dependent substrate depletion regulates nitric oxide production (vol 166, pg 2173, 2001)
   JOURNAL OF IMMUNOLOGY
   
   R. Rutschman et al., "Cutting edge: Stat6-dependent substrate depletion regulates nitric oxide production (vol 166, pg 2173, 2001)", J IMMUNOL, 166(7), 2001, pp. 4788-4788
7. Rutschman, R; Lang, R; Hesse, M; Ihle, JN; Wynn, TA; Murray, PJ
   Cutting edge: Stat6-dependent substrate depletion regulates nitric oxide production
   JOURNAL OF IMMUNOLOGY
   
   R. Rutschman et al., "Cutting edge: Stat6-dependent substrate depletion regulates nitric oxide production", J IMMUNOL, 166(4), 2001, pp. 2173-2177
8. Belkaid, Y; Hoffmann, KF; Mendez, S; Kamhawi, S; Udey, MC; Wynn, TA; Sacks, DL
   The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptorantibody for sterile cure
   JOURNAL OF EXPERIMENTAL MEDICINE
   
   Y. Belkaid et al., "The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptorantibody for sterile cure", J EXP MED, 194(10), 2001, pp. 1497-1506
9. Kullberg, MC; Rothfuchs, AG; Jankovic, D; Caspar, P; Wynn, TA; Gorelick, PL; Cheever, AW; Sher, A
   Helicobacter hepaticus-induced colitis in interleukin-10-deficient mice: Cytokine requirements for the induction and maintenance of intestinal inflammation
   INFECTION AND IMMUNITY
   
   M.C. Kullberg et al., "Helicobacter hepaticus-induced colitis in interleukin-10-deficient mice: Cytokine requirements for the induction and maintenance of intestinal inflammation", INFEC IMMUN, 69(7), 2001, pp. 4232-4241
10. Park, MK; Hoffmann, KF; Cheever, AW; Amichay, D; Wynn, TA; Farber, JM
    Patterns of chemokine expression in models of Schistosoma mansoni inflammation and infection reveal relationships between type 1 and type 2 responsesand chemokines in vivo
    INFECTION AND IMMUNITY
    
    M.K. Park et al., "Patterns of chemokine expression in models of Schistosoma mansoni inflammation and infection reveal relationships between type 1 and type 2 responsesand chemokines in vivo", INFEC IMMUN, 69(11), 2001, pp. 6755-6768
11. Wynn, TA; Hoffmann, KF
    Defining a schistosomiasis vaccination strategy - Is really Th1 versus Th2?
    PARASITOLOGY TODAY
    
    T.A. Wynn e K.F. Hoffmann, "Defining a schistosomiasis vaccination strategy - Is really Th1 versus Th2?", PARASIT TOD, 16(11), 2000, pp. 497-501
12. Cheever, AW; Hoffmann, KF; Wynn, TA
    Immunopathology of schistosomiasis mansoni in mice and men
    IMMUNOLOGY TODAY
    
    A.W. Cheever et al., "Immunopathology of schistosomiasis mansoni in mice and men", IMMUNOL TOD, 21(9), 2000, pp. 465-466
13. Chiaramonte, MG; Hesse, M; Cheever, AW; Wynn, TA
    CpG oligonucleotides can prophylactically immunize against Th2-mediated schistosome egg-induced pathology by an IL-12-independent mechanism
    JOURNAL OF IMMUNOLOGY
    
    M.G. Chiaramonte et al., "CpG oligonucleotides can prophylactically immunize against Th2-mediated schistosome egg-induced pathology by an IL-12-independent mechanism", J IMMUNOL, 164(2), 2000, pp. 973-985
14. Hoffmann, KF; Cheever, AW; Wynn, TA
    IL-10 and the dangers of immune polarization: Excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis
    JOURNAL OF IMMUNOLOGY
    
    K.F. Hoffmann et al., "IL-10 and the dangers of immune polarization: Excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis", J IMMUNOL, 164(12), 2000, pp. 6406-6416
15. Hesse, M; Cheever, AW; Jankovic, D; Wynn, TA
    NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease
    AMERICAN JOURNAL OF PATHOLOGY
    
    M. Hesse et al., "NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease", AM J PATH, 157(3), 2000, pp. 945-955
16. Wynn, TA
    Immune deviation as a strategy for schistosomiasis vaccines designed to prevent infection and egg-induced immunopathology
    MICROBES AND INFECTION
    
    T.A. Wynn, "Immune deviation as a strategy for schistosomiasis vaccines designed to prevent infection and egg-induced immunopathology", MICROBES IN, 1(7), 1999, pp. 525-534
17. Colley, DG; Wilson, RA; Wolowczuk, I; Wynn, TA; Boros, DL; Coulson, PS; Capron, A; Stadecker, MJ
    Commentary on the Forum 'Immunoregulation of schistosomiasis'
    MICROBES AND INFECTION
    
    D.G. Colley et al., "Commentary on the Forum 'Immunoregulation of schistosomiasis'", MICROBES IN, 1(7), 1999, pp. 569-574
18. Finkelman, FD; Wynn, TA; Donaldson, DD; Urban, JF
    The role of IL-13 in helminth-induced inflammation and protective immunityagainst nematode infections
    CURRENT OPINION IN IMMUNOLOGY
    
    F.D. Finkelman et al., "The role of IL-13 in helminth-induced inflammation and protective immunityagainst nematode infections", CURR OP IM, 11(4), 1999, pp. 420-426
19. Montenegro, SML; Miranda, P; Mahanty, S; Abath, FGC; Teixeira, KM; Coutinho, EM; Brinkman, J; Goncalves, I; Domingues, LAW; Domingues, ALC; Sher, A; Wynn, TA
    Cytokine production in acute versus chronic human schistosomiasis mansoni:The cross-regulatory role of interferon-gamma and interleukin-10 in the responses of peripheral blood mononuclear cells and splenocytes to parasite antigens
    JOURNAL OF INFECTIOUS DISEASES
    
    S.M.L. Montenegro et al., "Cytokine production in acute versus chronic human schistosomiasis mansoni:The cross-regulatory role of interferon-gamma and interleukin-10 in the responses of peripheral blood mononuclear cells and splenocytes to parasite antigens", J INFEC DIS, 179(6), 1999, pp. 1502-1514
20. Hoffmann, KF; James, SL; Cheever, AW; Wynn, TA
    Studies with double cytokine-deficient mice reveal that highly polarized Th1-and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni
    JOURNAL OF IMMUNOLOGY
    
    K.F. Hoffmann et al., "Studies with double cytokine-deficient mice reveal that highly polarized Th1-and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni", J IMMUNOL, 163(2), 1999, pp. 927-938
21. Chiaramonte, MG; Schopf, LR; Neben, TY; Cheever, AW; Donaldson, DD; Wynn, TA
    IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs
    JOURNAL OF IMMUNOLOGY
    
    M.G. Chiaramonte et al., "IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs", J IMMUNOL, 162(2), 1999, pp. 920-930
22. Jankovic, D; Wynn, TA; Kullberg, MC; Hieny, S; Caspar, P; James, S; Cheever, AW; Sher, A
    Optimal vaccination against Schistosoma mansoni requires the induction of both B cell- and IFN-gamma-dependent effector mechanisms
    JOURNAL OF IMMUNOLOGY
    
    D. Jankovic et al., "Optimal vaccination against Schistosoma mansoni requires the induction of both B cell- and IFN-gamma-dependent effector mechanisms", J IMMUNOL, 162(1), 1999, pp. 345-351
23. Chiaramonte, MG; Donaldson, DD; Cheever, AW; Wynn, TA
    An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response
    JOURNAL OF CLINICAL INVESTIGATION
    
    M.G. Chiaramonte et al., "An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response", J CLIN INV, 104(6), 1999, pp. 777-785
24. Cheever, AW; Poindexter, RW; Wynn, TA
    Egg laying is delayed but worm fecundity is normal in SCID mice infected with Schistosoma japonicum and S-mansoni with or without recombinant tumor necrosis factor alpha treatment
    INFECTION AND IMMUNITY
    
    A.W. Cheever et al., "Egg laying is delayed but worm fecundity is normal in SCID mice infected with Schistosoma japonicum and S-mansoni with or without recombinant tumor necrosis factor alpha treatment", INFEC IMMUN, 67(5), 1999, pp. 2201-2208
25. Segal, BH; Doherty, TM; Wynn, TA; Cheever, AW; Sher, A; Holland, SM
    The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs
    INFECTION AND IMMUNITY
    
    B.H. Segal et al., "The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs", INFEC IMMUN, 67(4), 1999, pp. 1659-1665
26. Mountford, AP; Coulson, PS; Cheever, AW; Sher, A; Wilson, RA; Wynn, TA
    Interleukin-12 can directly induce T-helper 1 responses in interferon-gamma (IFN-gamma) receptor-deficient mice, but requires IFN-gamma signalling todownregulate T-helper 2 responses
    IMMUNOLOGY
    
    A.P. Mountford et al., "Interleukin-12 can directly induce T-helper 1 responses in interferon-gamma (IFN-gamma) receptor-deficient mice, but requires IFN-gamma signalling todownregulate T-helper 2 responses", IMMUNOLOGY, 97(4), 1999, pp. 588-594
27. SEGAL BH; WYNN TA; DOHERTY TM; SHER A; CHEEVER AW; HOLLAND SM
    TH-1 AND TH-2 RESPONSES TO MYCOBACTERIUM-AVIUM (MA) AND SCHISTOSOMA-MANSONI EGGS (SME) ARE NORMAL IN THE P47(PHOX- -) KNOCKOUT (KO) MOUSE MODEL OF CHRONIC GRANULOMATOUS-DISEASE (CGD)/
    Journal of investigative medicine
    
    B.H. Segal et al., "TH-1 AND TH-2 RESPONSES TO MYCOBACTERIUM-AVIUM (MA) AND SCHISTOSOMA-MANSONI EGGS (SME) ARE NORMAL IN THE P47(PHOX- -) KNOCKOUT (KO) MOUSE MODEL OF CHRONIC GRANULOMATOUS-DISEASE (CGD)/", Journal of investigative medicine, 46(3), 1998, pp. 218-218
28. CHEEVER AW; JANKOVIC D; YAP GS; KULLBERG MC; SHER A; WYNN TA
    ROLE OF CYTOKINES IN THE FORMATION AND DOWN-REGULATION OF HEPATIC CIRCUMOVAL GRANULOMAS AND HEPATIC-FIBROSIS IN SCHISTOSOMA-MANSONI-INFECTED MICE
    Memorias do Instituto Oswaldo Cruz
    
    A.W. Cheever et al., "ROLE OF CYTOKINES IN THE FORMATION AND DOWN-REGULATION OF HEPATIC CIRCUMOVAL GRANULOMAS AND HEPATIC-FIBROSIS IN SCHISTOSOMA-MANSONI-INFECTED MICE", Memorias do Instituto Oswaldo Cruz, 93, 1998, pp. 25-32
29. MONTENEGRO SML; MIRANDA P; ABATH FGC; TEIXEIRA KM; COUTINHO EM; DOMINGUES ALC; DOMINGUES L; BRINKMAN J; GONCALVES I; MAHANTY S; SHER A; WYNN TA
    PRELIMINARY-RESULTS ON THE REGULATORY ROLE OF IFN-GAMMA AND IL-10 HUMAN SCHISTOSOMIASIS-MANSONI
    Memorias do Instituto Oswaldo Cruz
    
    S.M.L. Montenegro et al., "PRELIMINARY-RESULTS ON THE REGULATORY ROLE OF IFN-GAMMA AND IL-10 HUMAN SCHISTOSOMIASIS-MANSONI", Memorias do Instituto Oswaldo Cruz, 93, 1998, pp. 173-173
30. HOFFMANN KF; CASPAR P; CHEEVER AW; WYNN TA
    IFN-GAMMA, IL-12, AND TNF-ALPHA ARE REQUIRED TO MAINTAIN REDUCED LIVER PATHOLOGY IN MICE VACCINATED WITH SCHISTOSOMA-MANSONI EGGS AND IL-12
    The Journal of immunology (1950)
    
    K.F. Hoffmann et al., "IFN-GAMMA, IL-12, AND TNF-ALPHA ARE REQUIRED TO MAINTAIN REDUCED LIVER PATHOLOGY IN MICE VACCINATED WITH SCHISTOSOMA-MANSONI EGGS AND IL-12", The Journal of immunology (1950), 161(8), 1998, pp. 4201-4210
31. WYNN TA; CHEEVER AW; WILLIAMS ME; HIENY S; CASPAR P; KUHN R; MULLER W; SHER A
    IL-10 REGULATES LIVER PATHOLOGY IN ACUTE MURINE SCHISTOSOMIASIS-MANSONI BUT IS NOT REQUIRED FOR IMMUNE DOWN-MODULATION OF CHRONIC DISEASE
    The Journal of immunology
    
    T.A. Wynn et al., "IL-10 REGULATES LIVER PATHOLOGY IN ACUTE MURINE SCHISTOSOMIASIS-MANSONI BUT IS NOT REQUIRED FOR IMMUNE DOWN-MODULATION OF CHRONIC DISEASE", The Journal of immunology, 160(9), 1998, pp. 4473-4480
32. JANKOVIC D; CHEEVER AW; KULLBERG MC; WYNN TA; YAP G; CASPAR P; LEWIS FA; CLYNES R; RAVETCH JV; SHER A
    CD4-CELL-MEDIATED GRANULOMATOUS PATHOLOGY IN SCHISTOSOMIASIS IS DOWN-REGULATED BY A B-CELL-DEPENDENT MECHANISM REQUIRING FC RECEPTOR SIGNALING( T)
    The Journal of experimental medicine
    
    D. Jankovic et al., "CD4-CELL-MEDIATED GRANULOMATOUS PATHOLOGY IN SCHISTOSOMIASIS IS DOWN-REGULATED BY A B-CELL-DEPENDENT MECHANISM REQUIRING FC RECEPTOR SIGNALING( T)", The Journal of experimental medicine, 187(4), 1998, pp. 619-629
33. JAMES SL; CHEEVER AW; CASPAR P; WYNN TA
    INDUCIBLE NITRIC-OXIDE SYNTHASE-DEFICIENT MICE DEVELOP ENHANCED TYPE-1 CYTOKINE-ASSOCIATED CELLULAR AND HUMORAL IMMUNE-RESPONSES AFTER VACCINATION WITH ATTENUATED SCHISTOSOMA-MANSONI CERCARIAE BUT DISPLAY PARTIALLY REDUCED RESISTANCE
    Infection and immunity
    
    S.L. James et al., "INDUCIBLE NITRIC-OXIDE SYNTHASE-DEFICIENT MICE DEVELOP ENHANCED TYPE-1 CYTOKINE-ASSOCIATED CELLULAR AND HUMORAL IMMUNE-RESPONSES AFTER VACCINATION WITH ATTENUATED SCHISTOSOMA-MANSONI CERCARIAE BUT DISPLAY PARTIALLY REDUCED RESISTANCE", Infection and immunity, 66(8), 1998, pp. 3510-3518
34. OSWALD IP; CASPAR P; WYNN TA; SCHARTONKERSTEN T; WILLIAMS ME; HIENY S; SHER A; JAMES SL
    FAILURE OF P-STRAIN MICE TO RESPOND TO VACCINATION AGAINST SCHISTOSOMIASIS CORRELATES WITH IMPAIRED PRODUCTION OF IL-12 AND UP-REGULATION OF TH2 CYTOKINES THAT INHIBIT MACROPHAGE ACTIVATION
    European Journal of Immunology
    
    I.P. Oswald et al., "FAILURE OF P-STRAIN MICE TO RESPOND TO VACCINATION AGAINST SCHISTOSOMIASIS CORRELATES WITH IMPAIRED PRODUCTION OF IL-12 AND UP-REGULATION OF TH2 CYTOKINES THAT INHIBIT MACROPHAGE ACTIVATION", European Journal of Immunology, 28(6), 1998, pp. 1762-1772
35. CHEEVER AW; LEWIS FA; WYNN TA
    SCHISTOSOMA-MANSONI - UNISEXUAL INFECTIONS SENSITIZE MICE FOR GRANULOMA-FORMATION AROUND INTRAVENOUSLY INJECTED EGGS
    Parasitology research
    
    A.W. Cheever et al., "SCHISTOSOMA-MANSONI - UNISEXUAL INFECTIONS SENSITIZE MICE FOR GRANULOMA-FORMATION AROUND INTRAVENOUSLY INJECTED EGGS", Parasitology research, 83(1), 1997, pp. 57-59
36. WYNN TA
    THE DEBATE OVER THE EFFECTOR FUNCTION OF EOSINOPHILS IN HELMINTH INFECTION - NEW EVIDENCE FROM STUDIES ON THE REGULATION OF VACCINE IMMUNITY BY IL-12
    Memorias do Instituto Oswaldo Cruz
    
    T.A. Wynn, "THE DEBATE OVER THE EFFECTOR FUNCTION OF EOSINOPHILS IN HELMINTH INFECTION - NEW EVIDENCE FROM STUDIES ON THE REGULATION OF VACCINE IMMUNITY BY IL-12", Memorias do Instituto Oswaldo Cruz, 92, 1997, pp. 105-108
37. WYNN TA; MORAWETZ R; SCHARTONKERSTEN T; HIENY S; MORSE HC; KUHN R; MULLER W; CHEEVER AW; SHER A
    ANALYSIS OF GRANULOMA-FORMATION IN DOUBLE CYTOKINE-DEFICIENT MICE REVEALS A CENTRAL ROLE FOR IL-10 IN POLARIZING BOTH T-HELPER CELL 1-TYPE AND T-HELPER CELL 2-TYPE CYTOKINE RESPONSES IN-VIVO
    The Journal of immunology
    
    T.A. Wynn et al., "ANALYSIS OF GRANULOMA-FORMATION IN DOUBLE CYTOKINE-DEFICIENT MICE REVEALS A CENTRAL ROLE FOR IL-10 IN POLARIZING BOTH T-HELPER CELL 1-TYPE AND T-HELPER CELL 2-TYPE CYTOKINE RESPONSES IN-VIVO", The Journal of immunology, 159(10), 1997, pp. 5014-5023
38. JANKOVIC D; KULLBERG MC; DOMBROWICZ D; BARBIERI S; CASPAR P; WYNN TA; PAUL WE; CHEEVER AW; KINET JP; SHER A
    FC-EPSILON-RI-DEFICIENT MICE INFECTED WITH SCHISTOSOMA-MANSONI MOUNT NORMAL TH2-TYPE RESPONSES WHILE DISPLAYING ENHANCED LIVER PATHOLOGY
    The Journal of immunology
    
    D. Jankovic et al., "FC-EPSILON-RI-DEFICIENT MICE INFECTED WITH SCHISTOSOMA-MANSONI MOUNT NORMAL TH2-TYPE RESPONSES WHILE DISPLAYING ENHANCED LIVER PATHOLOGY", The Journal of immunology, 159(4), 1997, pp. 1868-1875
39. GAO JL; WYNN TA; CHANG Y; LEE EJ; BROXMEYER HE; COOPER S; TIFFANY HL; WESTPHAL H; KWONCHUNG J; MURPHY PM
    IMPAIRED HOST-DEFENSE, HEMATOPOIESIS, GUANULOMATOUS INFLAMMATION AND TYPE-1 TYPE-2 CYTOKINE BALANCE IN MICE LACKING CC CHEMOKINE RECEPTOR-1
    The Journal of experimental medicine
    
    J.L. Gao et al., "IMPAIRED HOST-DEFENSE, HEMATOPOIESIS, GUANULOMATOUS INFLAMMATION AND TYPE-1 TYPE-2 CYTOKINE BALANCE IN MICE LACKING CC CHEMOKINE RECEPTOR-1", The Journal of experimental medicine, 185(11), 1997, pp. 1959-1968
40. WYNN TA; SHER A
    HOT PAPERS - IMMUNOLOGY PARASITOLOGY - ENDOGENOUS INTERLEUKIN-12 (IL-12) REGULATES GRANULOMA-FORMATION INDUCED BY EGGS OF SCHISTOSOMA-MANSONI AND EXOGENOUS IL-12 BOTH INHIBITS AND PROPHYLACTICALLY IMMUNIZES AGAINST EGG PATHOLOGY BY WYNN,T.A., ELTOUM,I., OSWALD,I.P., CHEEVER,A.W., SHER,A. - COMMENTS
    The Scientist
    
    T.A. Wynn e A. Sher, "HOT PAPERS - IMMUNOLOGY PARASITOLOGY - ENDOGENOUS INTERLEUKIN-12 (IL-12) REGULATES GRANULOMA-FORMATION INDUCED BY EGGS OF SCHISTOSOMA-MANSONI AND EXOGENOUS IL-12 BOTH INHIBITS AND PROPHYLACTICALLY IMMUNIZES AGAINST EGG PATHOLOGY BY WYNN,T.A., ELTOUM,I., OSWALD,I.P., CHEEVER,A.W., SHER,A. - COMMENTS", The Scientist, 10(9), 1996, pp. 14-14
41. CHOUGNET C; WYNN TA; CLERICI M; LANDAY AL; KESSLER HA; RUSNAK J; MELCHER GP; SHER A; SHEARER GM
    MOLECULAR ANALYSIS OF DECREASED INTERLEUKIN-12 PRODUCTION IN PERSONS INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS
    The Journal of infectious diseases
    
    C. Chougnet et al., "MOLECULAR ANALYSIS OF DECREASED INTERLEUKIN-12 PRODUCTION IN PERSONS INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS", The Journal of infectious diseases, 174(1), 1996, pp. 46-53
42. SCHARTONKERSTEN TM; WYNN TA; DENKERS EY; BALA S; GRUNVALD E; HIENY S; GAZZINELLI RT; SHER A
    IN THE ABSENCE OF ENDOGENOUS IFN-GAMMA, MICE DEVELOP UNIMPAIRED IL-12RESPONSES TO TOXOPLASMA-GONDII WHILE FAILING TO CONTROL ACUTE INFECTION
    The Journal of immunology
    
    T.M. Schartonkersten et al., "IN THE ABSENCE OF ENDOGENOUS IFN-GAMMA, MICE DEVELOP UNIMPAIRED IL-12RESPONSES TO TOXOPLASMA-GONDII WHILE FAILING TO CONTROL ACUTE INFECTION", The Journal of immunology, 157(9), 1996, pp. 4045-4054
43. WYNN TA; REYNOLDS A; JAMES S; CHEEVER AW; CASPAR P; HIENY S; JANKOVIC D; STRAND M; SHER A
    IL-12 ENHANCES VACCINE-INDUCED IMMUNITY TO SCHISTOSOMES BY AUGMENTINGBOTH HUMORAL AND CELL-MEDIATED IMMUNE-RESPONSES AGAINST THE PARASITE
    The Journal of immunology
    
    T.A. Wynn et al., "IL-12 ENHANCES VACCINE-INDUCED IMMUNITY TO SCHISTOSOMES BY AUGMENTINGBOTH HUMORAL AND CELL-MEDIATED IMMUNE-RESPONSES AGAINST THE PARASITE", The Journal of immunology, 157(9), 1996, pp. 4068-4078
44. BROWN DR; FOWELL DJ; CORRY DB; WYNN TA; MOSKOWITZ NH; CHEEVER AW; LOCKSLEY RM; REINER SL
    BETA-2-MICROGLOBULIN-DEPENDENT NK1.1(-CELLS ARE NOT ESSENTIAL FOR T-HELPER CELL 2 IMMUNE-RESPONSES() T)
    The Journal of experimental medicine
    
    D.R. Brown et al., "BETA-2-MICROGLOBULIN-DEPENDENT NK1.1(-CELLS ARE NOT ESSENTIAL FOR T-HELPER CELL 2 IMMUNE-RESPONSES() T)", The Journal of experimental medicine, 184(4), 1996, pp. 1295-1304
45. WYNN TA; CHEEVER AW
    CYTOKINE REGULATION OF GRANULOMA-FORMATION IN SCHISTOSOMIASIS
    Current opinion in immunology
    
    T.A. Wynn e A.W. Cheever, "CYTOKINE REGULATION OF GRANULOMA-FORMATION IN SCHISTOSOMIASIS", Current opinion in immunology, 7(4), 1995, pp. 505-511
46. WYNN TA; SHER A
    IL12 AS AN ADJUVANT FOR VACCINES DESIGNED TO PREVENT INFECTION AND IMMUNOPATHOLOGY BY SCHISTOSOMES
    Research in immunology
    
    T.A. Wynn e A. Sher, "IL12 AS AN ADJUVANT FOR VACCINES DESIGNED TO PREVENT INFECTION AND IMMUNOPATHOLOGY BY SCHISTOSOMES", Research in immunology, 146(7-8), 1995, pp. 582-589
47. WYNN TA; SHER A
    IL12 AS AN ADJUVANT FOR VACCINES DESIGNED TO PREVENT INFECTION AND IMMUNOPATHOLOGY BY SCHISTOSOMES - REPLY
    Research in immunology
    
    T.A. Wynn e A. Sher, "IL12 AS AN ADJUVANT FOR VACCINES DESIGNED TO PREVENT INFECTION AND IMMUNOPATHOLOGY BY SCHISTOSOMES - REPLY", Research in immunology, 146(7-8), 1995, pp. 590-590
48. CLERICI M; SARIN A; LUCEY DR; PINTO LA; WYNN TA; BLATT SP; HENDRIX CW; DOLAN MJ; WOLF SF; BERZOFSKY JA; HENKART PA; SHEARER GM
    MODIFICATION OF THE IMMUNE-RESPONSE IN HIV-INFECTION BY TYPE-1 TYPE-2CYTOKINE REGULATION
    Journal of cellular biochemistry
    
    M. Clerici et al., "MODIFICATION OF THE IMMUNE-RESPONSE IN HIV-INFECTION BY TYPE-1 TYPE-2CYTOKINE REGULATION", Journal of cellular biochemistry, 1995, pp. 60-60
49. WYNN TA; JANKOVIC D; POINDEXTER R; CASPAR P; CHEEVER A; SHER A
    VACCINATION WITH PARASITE (EGG) ANTIGEN PLUS IL-12 SWITCHES HELMINTH-INDUCED CYTOKINE RESPONSES FROM A TH2 TO A TH1 PATTERN AND BLOCKS PATHOLOGY
    Journal of cellular biochemistry
    
    T.A. Wynn et al., "VACCINATION WITH PARASITE (EGG) ANTIGEN PLUS IL-12 SWITCHES HELMINTH-INDUCED CYTOKINE RESPONSES FROM A TH2 TO A TH1 PATTERN AND BLOCKS PATHOLOGY", Journal of cellular biochemistry, 1995, pp. 182-182
50. WYNN TA; CHEEVER AW; JANKOVIC D; POINDEXTER RW; CASPAR P; LEWIS FA; SHER A
    AN IL-12-BASED VACCINATION METHOD FOR PREVENTING FIBROSIS INDUCED BY SCHISTOSOME INFECTION
    Nature
    
    T.A. Wynn et al., "AN IL-12-BASED VACCINATION METHOD FOR PREVENTING FIBROSIS INDUCED BY SCHISTOSOME INFECTION", Nature, 376(6541), 1995, pp. 594-596
51. SALKOWSKI CA; NETA R; WYNN TA; STRASSMANN G; VANROOIJEN N; VOGEL SN
    EFFECT OF LIPOSOME-MEDIATED MACROPHAGE DEPLETION ON LPS-INDUCED CYTOKINE GENE-EXPRESSION AND RADIOPROTECTION
    The Journal of immunology
    
    C.A. Salkowski et al., "EFFECT OF LIPOSOME-MEDIATED MACROPHAGE DEPLETION ON LPS-INDUCED CYTOKINE GENE-EXPRESSION AND RADIOPROTECTION", The Journal of immunology, 155(6), 1995, pp. 3168-3179
52. WYNN TA; JANKOVIC D; HIENY S; CHEEVER AW; SHER A
    IL-12 ENHANCES VACCINE-INDUCED IMMUNITY TO SCHISTOSOMA-MANSONI IN MICE AND DECREASES T-HELPER-2 CYTOKINE EXPRESSION, IGE PRODUCTION, AND TISSUE EOSINOPHILIA
    The Journal of immunology
    
    T.A. Wynn et al., "IL-12 ENHANCES VACCINE-INDUCED IMMUNITY TO SCHISTOSOMA-MANSONI IN MICE AND DECREASES T-HELPER-2 CYTOKINE EXPRESSION, IGE PRODUCTION, AND TISSUE EOSINOPHILIA", The Journal of immunology, 154(9), 1995, pp. 4701-4709
53. WYNN TA; JANKOVIC D; HIENY S; ZIONCHECK K; JARDIEU P; CHEEVER AW; SHER A
    IL-12 EXACERBATES RATHER THAN SUPPRESSES T-HELPER 2-DEPENDENT PATHOLOGY IN THE ABSENCE OF ENDOGENOUS IFN-GAMMA
    The Journal of immunology
    
    T.A. Wynn et al., "IL-12 EXACERBATES RATHER THAN SUPPRESSES T-HELPER 2-DEPENDENT PATHOLOGY IN THE ABSENCE OF ENDOGENOUS IFN-GAMMA", The Journal of immunology, 154(8), 1995, pp. 3999-4009
54. ELTOUM IA; WYNN TA; POINDEXTER RW; FINKELMAN FD; LEWIS FA; SHER A; CHEEVER AW
    SUPPRESSIVE EFFECT OF INTERLEUKIN-4 NEUTRALIZATION DIFFERS FOR GRANULOMAS AROUND SCHISTOSOMA-MANSONI EGGS INJECTED INTO MICE COMPARED WITH THOSE AROUND EGGS LAID IN INFECTED MICE
    Infection and immunity
    
    I.A. Eltoum et al., "SUPPRESSIVE EFFECT OF INTERLEUKIN-4 NEUTRALIZATION DIFFERS FOR GRANULOMAS AROUND SCHISTOSOMA-MANSONI EGGS INJECTED INTO MICE COMPARED WITH THOSE AROUND EGGS LAID IN INFECTED MICE", Infection and immunity, 63(7), 1995, pp. 2532-2536
55. FERNANDEZBOTRAN R; WYNN TA; HIENY S; CASPAR P; CHILTON PM; SHER A
    LINKED IN-VIVO EXPRESSION OF SOLUBLE INTERLEUKIN-4 RECEPTOR AND INTERLEUKIN-4 IN MURINE SCHISTOSOMIASIS
    European Journal of Immunology
    
    R. Fernandezbotran et al., "LINKED IN-VIVO EXPRESSION OF SOLUBLE INTERLEUKIN-4 RECEPTOR AND INTERLEUKIN-4 IN MURINE SCHISTOSOMIASIS", European Journal of Immunology, 25(3), 1995, pp. 649-656
56. OSWALD IP; WYNN TA; SHER A; JAMES SL
    NO AS AN EFFECTOR MOLECULE OF PARASITE KILLING - MODULATION OF ITS SYNTHESIS BY CYTOKINES
    Comparative biochemistry and physiology. Part C, Pharmacology toxicology & endocrinology
    
    I.P. Oswald et al., "NO AS AN EFFECTOR MOLECULE OF PARASITE KILLING - MODULATION OF ITS SYNTHESIS BY CYTOKINES", Comparative biochemistry and physiology. Part C, Pharmacology toxicology & endocrinology, 108(1), 1994, pp. 11-18
57. WYNN TA; ELTOUM I; OSWALD IP; CHEEVER AW; SHER A
    ENDOGENOUS AND EXOGENOUS REGULATION OF SCHISTOSOME EGG GRANULOMA-FORMATION BY IL-12
    The FASEB journal
    
    T.A. Wynn et al., "ENDOGENOUS AND EXOGENOUS REGULATION OF SCHISTOSOME EGG GRANULOMA-FORMATION BY IL-12", The FASEB journal, 8(5), 1994, pp. 10000966-10000966
58. OSWALD IP; WYNN TA; CASPAR P; SHER PA; JAMES SL
    HUMAN MACROPHAGES AND ENDOTHELIAL-CELLS EXHIBIT CYTOTOXICITY TOWARD EXTRACELLULAR TARGETS BY A NOVEL NO AND ROI INDEPENDENT MECHANISM
    The FASEB journal
    
    I.P. Oswald et al., "HUMAN MACROPHAGES AND ENDOTHELIAL-CELLS EXHIBIT CYTOTOXICITY TOWARD EXTRACELLULAR TARGETS BY A NOVEL NO AND ROI INDEPENDENT MECHANISM", The FASEB journal, 8(5), 1994, pp. 10000968-10000968
59. FERNANDEZBOTRAN R; HIENY S; CHILTON PM; WYNN TA; SHER A
    REGULATION OF THE SECRETION OF SOLUBLE INTERLEUKIN-4 RECEPTOR (SIL-4R) DURING MURINE SCHISTOSOMIASIS - CORRELATION WITH IL-4 PRODUCTION
    The FASEB journal
    
    R. Fernandezbotran et al., "REGULATION OF THE SECRETION OF SOLUBLE INTERLEUKIN-4 RECEPTOR (SIL-4R) DURING MURINE SCHISTOSOMIASIS - CORRELATION WITH IL-4 PRODUCTION", The FASEB journal, 8(5), 1994, pp. 10000996-10000996
60. OSWALD IP; ELTOUM I; WYNN TA; SCHWARTZ B; CASPAR P; PAULIN D; SHER A; JAMES SL
    ENDOTHELIAL-CELLS ARE ACTIVATED BY CYTOKINE TREATMENT TO KILL AN INTRAVASCULAR PARASITE, SCHISTOSOMA-MANSONI, THROUGH THE PRODUCTION OF NITRIC-OXIDE
    Proceedings of the National Academy of Sciences of the United Statesof America
    
    I.P. Oswald et al., "ENDOTHELIAL-CELLS ARE ACTIVATED BY CYTOKINE TREATMENT TO KILL AN INTRAVASCULAR PARASITE, SCHISTOSOMA-MANSONI, THROUGH THE PRODUCTION OF NITRIC-OXIDE", Proceedings of the National Academy of Sciences of the United Statesof America, 91(3), 1994, pp. 999-1003
61. CLERICI M; SARIN A; COFFMAN RL; WYNN TA; BLATT SP; HENDRIX CW; WOLF SF; SHEARER GM; HENKART PA
    TYPE-1 TYPE-2 CYTOKINE MODULATION OF T-CELL PROGRAMMED CELL-DEATH AS A MODEL FOR HUMAN-IMMUNODEFICIENCY-VIRUS PATHOGENESIS
    Proceedings of the National Academy of Sciences of the United Statesof America
    
    M. Clerici et al., "TYPE-1 TYPE-2 CYTOKINE MODULATION OF T-CELL PROGRAMMED CELL-DEATH AS A MODEL FOR HUMAN-IMMUNODEFICIENCY-VIRUS PATHOGENESIS", Proceedings of the National Academy of Sciences of the United Statesof America, 91(25), 1994, pp. 11811-11815
62. WILLIAMS ME; MONTENEGRO S; DOMINGUES AL; WYNN TA; TEIXEIRA K; MAHANTY S; COUTINHO A; SHER A
    LEUKOCYTES OF PATIENTS WITH SCHISTOSOMA-MANSONI RESPOND WITH A TH2 PATTERN OF CYTOKINE PRODUCTION TO MITOGEN OR EGG ANTIGENS BUT WITH A TH0PATTERN TO WORM ANTIGENS
    The Journal of infectious diseases
    
    M.E. Williams et al., "LEUKOCYTES OF PATIENTS WITH SCHISTOSOMA-MANSONI RESPOND WITH A TH2 PATTERN OF CYTOKINE PRODUCTION TO MITOGEN OR EGG ANTIGENS BUT WITH A TH0PATTERN TO WORM ANTIGENS", The Journal of infectious diseases, 170(4), 1994, pp. 946-954
63. OSWALD IP; CASPAR P; JANKOVIC D; WYNN TA; PEARCE EJ; SHER A
    IL-12 INHIBITS TH2 CYTOKINE RESPONSES INDUCED BY EGGS OF SCHISTOSOMA-MANSONI
    The Journal of immunology
    
    I.P. Oswald et al., "IL-12 INHIBITS TH2 CYTOKINE RESPONSES INDUCED BY EGGS OF SCHISTOSOMA-MANSONI", The Journal of immunology, 153(4), 1994, pp. 1707-1713
64. CHEEVER AW; WILLIAMS ME; WYNN TA; FINKELMAN FD; SEDER RA; COX TM; HIENY S; CASPAR P; SHER A
    ANTI-IL-4 TREATMENT OF SCHISTOSOMA-MANSONI-INFECTED MICE INHIBITS DEVELOPMENT OF T-CELLS AND NON-B, NON-T CELLS EXPRESSING TH2 CYTOKINES WHILE DECREASING EGG-INDUCED HEPATIC-FIBROSIS
    The Journal of immunology
    
    A.W. Cheever et al., "ANTI-IL-4 TREATMENT OF SCHISTOSOMA-MANSONI-INFECTED MICE INHIBITS DEVELOPMENT OF T-CELLS AND NON-B, NON-T CELLS EXPRESSING TH2 CYTOKINES WHILE DECREASING EGG-INDUCED HEPATIC-FIBROSIS", The Journal of immunology, 153(2), 1994, pp. 753-759
65. WYNN TA; OSWALD IP; ELTOUM IA; CASPAR P; LOWENSTEIN CJ; LEWIS FA; JAMES SL; SHER A
    ELEVATED EXPRESSION OF TH1 CYTOKINES AND NITRIC-OXIDE SYNTHASE IN THELUNGS OF VACCINATED MICE AFTER CHALLENGE INFECTION WITH SCHISTOSOMA-MANSONI
    The Journal of immunology
    
    T.A. Wynn et al., "ELEVATED EXPRESSION OF TH1 CYTOKINES AND NITRIC-OXIDE SYNTHASE IN THELUNGS OF VACCINATED MICE AFTER CHALLENGE INFECTION WITH SCHISTOSOMA-MANSONI", The Journal of immunology, 153(11), 1994, pp. 5200-5209
66. WYNN TA; ELTOUM I; OSWALD IP; CHEEVER AW; SHER A
    ENDOGENOUS INTERLEUKIN-12 (IL12) REGULATES GRANULOMA-FORMATION INDUCED BY EGGS OF SCHISTOSOMA-MANSONI AND EXOGENOUS IL-12 BOTH INHIBITS ANDPROPHYLACTICALLY IMMUNIZES AGAINST EGG PATHOLOGY
    The Journal of experimental medicine
    
    T.A. Wynn et al., "ENDOGENOUS INTERLEUKIN-12 (IL12) REGULATES GRANULOMA-FORMATION INDUCED BY EGGS OF SCHISTOSOMA-MANSONI AND EXOGENOUS IL-12 BOTH INHIBITS ANDPROPHYLACTICALLY IMMUNIZES AGAINST EGG PATHOLOGY", The Journal of experimental medicine, 179(5), 1994, pp. 1551-1561
67. CLERICI M; WYNN TA; BERZOFSKY JA; BLATT SP; HENDRIX CW; SHER A; COFFMAN RL; SHEARER GM
    ROLE OF INTERLEUKIN-10 IN T-HELPER CELL DYSFUNCTION IN ASYMPTOMATIC INDIVIDUALS INFECTED WITH THE HUMAN-IMMUNODEFICIENCY-VIRUS
    The Journal of clinical investigation
    
    M. Clerici et al., "ROLE OF INTERLEUKIN-10 IN T-HELPER CELL DYSFUNCTION IN ASYMPTOMATIC INDIVIDUALS INFECTED WITH THE HUMAN-IMMUNODEFICIENCY-VIRUS", The Journal of clinical investigation, 93(2), 1994, pp. 768-775
68. OSWALD IP; WYNN TA; WILLIAMS ME; ELTOUM I; CHEEVER AW; JAMES SL; SHER A
    REGULATORY AND IMMUNOPATHOLOGICAL ROLES OF IL4 IN EXPERIMENTAL SCHISTOSOMIASIS
    Research in immunology
    
    I.P. Oswald et al., "REGULATORY AND IMMUNOPATHOLOGICAL ROLES OF IL4 IN EXPERIMENTAL SCHISTOSOMIASIS", Research in immunology, 144(8), 1993, pp. 643-648
69. CLERICI M; LUCEY DR; BERZOFSKY JA; PINTO LA; WYNN TA; BLATT SP; DOLAN MJ; HENDRIX CW; WOLF SF; SHEARER GM
    RESTORATION OF HIV-SPECIFIC CELL-MEDIATED IMMUNE-RESPONSES BY INTERLEUKIN-12 IN-VITRO
    Science
    
    M. Clerici et al., "RESTORATION OF HIV-SPECIFIC CELL-MEDIATED IMMUNE-RESPONSES BY INTERLEUKIN-12 IN-VITRO", Science, 262(5140), 1993, pp. 1721-1724
70. GAZZINELLI RT; HIENY S; WYNN TA; WOLF S; SHER A
    INTERLEUKIN-12 IS REQUIRED FOR THE T-LYMPHOCYTE-INDEPENDENT INDUCTIONOF INTERFERON-GAMMA BY AN INTRACELLULAR PARASITE AND INDUCES RESISTANCE IN T-CELL-DEFICIENT HOSTS
    Proceedings of the National Academy of Sciences of the United Statesof America
    
    R.T. Gazzinelli et al., "INTERLEUKIN-12 IS REQUIRED FOR THE T-LYMPHOCYTE-INDEPENDENT INDUCTIONOF INTERFERON-GAMMA BY AN INTRACELLULAR PARASITE AND INDUCES RESISTANCE IN T-CELL-DEFICIENT HOSTS", Proceedings of the National Academy of Sciences of the United Statesof America, 90(13), 1993, pp. 6115-6119
71. GAZZINELLI RT; ELTOUM I; WYNN TA; SHER A
    ACUTE CEREBRAL TOXOPLASMOSIS IS INDUCED BY IN-VIVO NEUTRALIZATION OF TNF-ALPHA AND CORRELATES WITH THE DOWN-REGULATED EXPRESSION OF INDUCIBLE NITRIC-OXIDE SYNTHASE AND OTHER MARKERS OF MACROPHAGE ACTIVATION
    The Journal of immunology
    
    R.T. Gazzinelli et al., "ACUTE CEREBRAL TOXOPLASMOSIS IS INDUCED BY IN-VIVO NEUTRALIZATION OF TNF-ALPHA AND CORRELATES WITH THE DOWN-REGULATED EXPRESSION OF INDUCIBLE NITRIC-OXIDE SYNTHASE AND OTHER MARKERS OF MACROPHAGE ACTIVATION", The Journal of immunology, 151(7), 1993, pp. 3672-3681
72. WYNN TA; ELTOUM I; CHEEVER AW; LEWIS FA; GAUSE WC; SHER A
    ANALYSIS OF CYTOKINE MESSENGER-RNA EXPRESSION DURING PRIMARY GRANULOMA-FORMATION INDUCED BY EGGS OF SCHISTOSOMA-MANSONI
    The Journal of immunology
    
    T.A. Wynn et al., "ANALYSIS OF CYTOKINE MESSENGER-RNA EXPRESSION DURING PRIMARY GRANULOMA-FORMATION INDUCED BY EGGS OF SCHISTOSOMA-MANSONI", The Journal of immunology, 151(3), 1993, pp. 1430-1440
73. OSWALD IP; ELTOUM I; WYNN TA; SHER A; JAMES SL
    ENDOTHELIAL-CELL MEDIATED KILLING OF LARVAL SCHISTOSOMES - ROLE OF CYTOKINES IN EFFECTOR CELL ACTIVATION AND REGULATION
    The Journal of immunology
    
    I.P. Oswald et al., "ENDOTHELIAL-CELL MEDIATED KILLING OF LARVAL SCHISTOSOMES - ROLE OF CYTOKINES IN EFFECTOR CELL ACTIVATION AND REGULATION", The Journal of immunology, 150(8), 1993, pp. 7-7
74. KARP CL; ELSAFI SH; WYNN TA; SATTI MMH; KORDOFANI AM; HASHIM FA; HAGALI M; NEVA FA; NUTMAN TB; SACKS DL
    INVIVO CYTOKINE PROFILES IN PATIENTS WITH KALA-AZAR - MARKED ELEVATION OF BOTH INTERLEUKIN-10 AND INTERFERON-GAMMA
    The Journal of clinical investigation
    
    C.L. Karp et al., "INVIVO CYTOKINE PROFILES IN PATIENTS WITH KALA-AZAR - MARKED ELEVATION OF BOTH INTERLEUKIN-10 AND INTERFERON-GAMMA", The Journal of clinical investigation, 91(4), 1993, pp. 1644-1648