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La ricerca find articoli where authors phrase all words 'STURZEBECHER J' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 54 riferimenti
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    1. Steinmetzer, T; Schweinitz, A; Kunzel, S; Wikstrom, P; Hauptmann, J; Sturzebecher, J
      Structure-activity relationships of new NAPAP-analogs

      JOURNAL OF ENZYME INHIBITION
    2. Steinmetzer, T; Hauptmann, J; Sturzebecher, J
      Advances in the development of thrombin inhibitors

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    3. Kamm, W; Hauptmann, J; Behrens, I; Sturzebecher, J; Dullweber, F; Gohlke, H; Stubbs, M; Klebe, G; Kissel, T
      Transport of peptidomimetic thrombin inhibitors with a 3-amidino-phenylalanine structure: Permeability and efflux mechanism in monolayers of a human intestinal cell line (Caco-2)

      PHARMACEUTICAL RESEARCH
    4. Dullweber, F; Stubbs, MT; Musil, D; Sturzebecher, J; Klebe, G
      Factorising ligand affinity: A combined thermodynamic and crystallographicstudy of trypsin and thrombin inhibition

      JOURNAL OF MOLECULAR BIOLOGY
    5. Steinmetzer, T; Batdordshjin, M; Pineda, F; Seyfarth, L; Vogel, A; Reissmann, S; Hauptmann, J; Sturzebecher, J
      New bivalent thrombin inhibitors with N-alpha(methyl)arginine at the P1-position

      BIOLOGICAL CHEMISTRY
    6. Sperl, S; Bergner, A; Sturzebecher, J; Magdolen, V; Bode, W; Moroder, L
      Urethanyl-3-amidinophenylalanine derivatives as inhibitors of factor Xa. X-ray crystal structure of a trypsin/inhibitor complex and modeling studies

      BIOLOGICAL CHEMISTRY
    7. Schmitt, M; Wilhelm, OG; Reuning, U; Kruger, A; Harbeck, N; Lengyel, E; Graeff, H; Gansbacher, B; Kessler, H; Burgle, M; Sturzebecher, J; Sperl, S; Magdolen, V
      The urokinase plasminogen activator system as a novel target for tumour therapy

      FIBRINOLYSIS & PROTEOLYSIS
    8. Sperl, S; Jacob, U; de Prada, NA; Sturzebecher, J; Wilhelm, OG; Bode, W; Magdolen, V; Huber, R; Moroder, L
      (4-Aminomethyl)phenylguanidine derivatives as nonpeptidic highly selectiveinhibitors of human urokinase

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    9. Zeslawska, E; Schweinitz, A; Karcher, A; Sondermann, P; Sperl, S; Sturzebecher, J; Jacob, U
      Crystals of the urokinase type plasminogen activator variant beta c-uPA incomplex with small molecule inhibitors open the way towards structure-based drug design

      JOURNAL OF MOLECULAR BIOLOGY
    10. Lauer, G; Sollberg, S; Cole, M; Flamme, I; Sturzebecher, J; Mann, K; Krieg, T; Eming, SA
      Expression and proteolysis of vascular endothelial growth factor is increased in chronic wounds

      JOURNAL OF INVESTIGATIVE DERMATOLOGY
    11. Steinmetzer, T; Batdorsdhjin, M; Kleinwachter, P; Seyfarth, L; Greiner, G; Reissmann, S; Sturzebecher, J
      New thrombin inhibitors based on D-Cha-Pro-derivatives

      JOURNAL OF ENZYME INHIBITION
    12. Sturzebecher, J; Vieweg, H; Steinmetzer, T; Schweinitz, A; Stubbs, MT; Renatus, M; Wikstrom, P
      3-amidinophenylalanine-based inhibitors of urokinase

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    13. Hauptmann, J; Sturzebecher, J
      Synthetic inhibitors of thrombin and factor Xa: From bench to bedside

      THROMBOSIS RESEARCH
    14. Sommerhoff, CP; Bode, W; Pereira, PJB; Stubbs, MT; Sturzebecher, J; Piechottka, GP; Matschiner, G; Bergner, A
      The structure of the human beta II-tryptase tetramer: Fo(u)r better or worse

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    15. Bohm, M; Sturzebecher, J; Klebe, G
      Three-dimensional quantitative structure-activity relationship analyses using comparative molecular field analysis and comparative molecular similarity indices analysis to elucidate selectivity differences of inhibitors binding to trypsin, thrombin, and factor Xa

      JOURNAL OF MEDICINAL CHEMISTRY
    16. Steinmetzer, T; Renatus, M; Kunzel, S; Eichinger, A; Bode, W; Wikstrom, P; Hauptmann, J; Sturzebecher, J
      Design and evaluation of novel bivalent thrombin inhibitors based on amidinophenylalanines

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    17. HAUPTMANN J; STURZEBECHER J
      INFLUENCE OF INDOCYANINE GREEN ON PLASMA DISAPPEARANCE AND BILIARY-EXCRETION OF A SYNTHETIC THROMBIN INHIBITOR OF THE 3-AMIDINOPHENYLALANINE PIPERAZIDE-TYPE IN RATS

      Pharmaceutical research
    18. Kolkhorst, V; Sturzebecher, J; Wiederanders, B
      Inhibition of tumour cell invasion by protease inhibitors: correlation with the protease profile

      JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
    19. PRASA D; STURZEBECHER J
      DETERMINATION OF ACTIVATED FACTOR-IX IN FACTOR-IX CONCENTRATES WITH ACHROMOGENIC SUBSTRATE

      Thrombosis research
    20. HAUPTMANN J; ALTMANN U; SCHWEINITZ A; STEINMETZER T; STURZEBECHER J
      ENANTIOSELECTIVE BIOTRANSFORMATION BUT NONSELECTIVE HEPATIC-UPTAKE AND BILIARY-EXCRETION OF A SYNTHETIC PEPTIDOMIMETIC THROMBIN INHIBITOR IN RATS

      Naunyn-Schmiedeberg's archives of pharmacology
    21. HAUPTMANN J; WICKSTROM P; STURZEBECHER J
      PLASMA-CLEARANCE AND BILIARY-EXCRETION OF N-ALPHA-NAPHTHYLSULFONYL-3-AMIDINOPHENYLALANINE PIPERAZIDE-TYPE THROMBIN INHIBITORS IN RATS

      Naunyn-Schmiedeberg's archives of pharmacology
    22. GABRIEL B; STUBBS MT; BERGNER A; HAUPTMANN J; BODE W; STURZEBECHER J; MORODER L
      DESIGN OF BENZAMIDINE-TYPE INHIBITORS OF FACTOR XA

      Journal of medicinal chemistry
    23. Renatus, M; Bode, W; Huber, R; Sturzebecher, J; Stubbs, MT
      Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: Implications for the inhibition of factor Xa, tPA, and urokinase

      JOURNAL OF MEDICINAL CHEMISTRY
    24. HALANGK W; STURZEBECHER J; MATTHIAS R; SCHULZ HU; LIPPERT H
      TRYPSINOGEN ACTIVATION IN RAT PANCREATIC ACINAR-CELLS HYPERSTIMULATEDBY CERULEIN

      Biochimica et biophysica acta. Molecular basis of disease
    25. GLUSA E; SAFT A; PRASA D; STURZEBECHER J
      TRYPSIN-INDUCED AND SLIGRL-INDUCED VASCULAR RELAXATION AND THE INHIBITION BY BENZAMIDINE DERIVATIVES

      Thrombosis and haemostasis
    26. PRASA D; SVENDSEN L; STURZEBECHER J
      THE ABILITY OF THROMBIN INHIBITORS TO REDUCE THE THROMBIN ACTIVITY GENERATED IN PLASMA ON EXTRINSIC AND INTRINSIC ACTIVATION

      Thrombosis and haemostasis
    27. PRASA D; SVENDSEN L; STURZEBECHER J
      INHIBITION OF THROMBIN GENERATION IN PLASMA BY INHIBITORS OF FACTOR XA

      Thrombosis and haemostasis
    28. HAUPTMANN J; WIKSTROM P; VIEWEG H; STURZEBECHER J
      COMPARATIVE-STUDIES ON THE BIOAVAILABILITY OF SYNTHETIC THROMBIN INHIBITORS

      Thrombosis and haemostasis
    29. STEINMETZER T; HAUPTMANN J; STURZEBECHER J; WIKSTROM P
      SYNTHESIS AND EVALUATION OF A NOVEL BIVALENT THROMBIN INHIBITOR CONTAINING A NON-SUBSTRATE-TYPE ACTIVE-SITE INHIBITOR BASED ON 3-AMIDINOPHENYLALANINE

      Thrombosis and haemostasis
    30. STURZEBECHER J; PRASA D; KOPETZKI E; HOPFNER KP; SVENDSEN L; WICKSTROM P
      DETERMINATION OF COAGULATION-FACTOR IXA USING CHROMOGENIC OR FLUOROGENIC SUBSTRATES

      Thrombosis and haemostasis
    31. STURZEBECHER J; KOPETZKI E; HOPFNER KP; WIKSTROM P; SVENDSEN L
      ALCOHOLS STIMULATE THE CATALYTIC ACTIVITY OF COAGULATION-FACTOR IXA

      Thrombosis and haemostasis
    32. HAUPTMANN J; ETEMAD F; ZIEGLER K; STURZEBECHER J; PETZINGER E
      UPTAKE IN RAT HEPATOCYTES AND HEPATIC-CLEARANCE IN-VIVO OF CATIONIC AMIDINOPHENYLANINE-DERIVED PEPTIDOMIMETIC THROMBIN INHIBITORS

      Naunyn-Schmiedeberg's archives of pharmacology
    33. GLUSA E; PRASA D; STURZEBECHER J
      ENDOTHELIUM-DEPENDENT RELAXATION INDUCED BY TRYPSIN AND THE PAR-2 PEPTIDE SLIRGL IN PORCINE PULMONARY-ARTERIES - INHIBITION BY BENZAMIDINE DERIVATIVES

      Naunyn-Schmiedeberg's archives of pharmacology
    34. STURZEBECHER J; PRASA D; HAUPTMANN J; VIEWEG H; WILKSTROM P
      SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF POTENT THROMBIN INHIBITORS - PIPERAZIDES OF 3-AMIDINOPHENYLALANINE

      Journal of medicinal chemistry
    35. RENATUS M; BODE W; HUBER R; STURZEBECHER J; PRASA D; FISCHER S; KOHNERT U; STUBBS MT
      STRUCTURAL MAPPING OF THE ACTIVE-SITE SPECIFICITY DETERMINANTS OF HUMAN TISSUE-TYPE PLASMINOGEN-ACTIVATOR - IMPLICATIONS FOR THE DESIGN OF LOW-MOLECULAR-WEIGHT SUBSTRATES AND INHIBITORS

      The Journal of biological chemistry
    36. STUBBS MT; MORENWEISER R; STURZEBECHER J; BAUER M; BODE W; HUBER R; PIECHOTTKA GP; MATSCHINER G; SOMMERHOFF CP; FRITZ H; AUERSWALD EA
      THE 3-DIMENSIONAL STRUCTURE OF RECOMBINANT LEECH-DERIVED TRYPTASE INHIBITOR IN COMPLEX WITH TRYPSIN - IMPLICATIONS FOR THE STRUCTURE OF HUMAN MAST-CELL TRYPTASE AND ITS INHIBITION

      The Journal of biological chemistry
    37. MORENWEISER R; AUERSWALD EA; VANDELOCHT A; FRITZ H; STURZEBECHER J; STUBBS MT
      STRUCTURE-BASED DESIGN OF A POTENT CHIMERIC THROMBIN INHIBITOR

      The Journal of biological chemistry
    38. STURZEBECHER J; KOPETZKI E; BODE W; HOPFNER KP
      DRAMATIC ENHANCEMENT OF THE CATALYTIC ACTIVITY OF COAGULATION-FACTOR IXA BY ALCOHOLS

      FEBS letters
    39. HU CK; KOHNERT U; STURZEBECHER J; FISCHER S; LLINAS M
      COMPLEXATION OF THE TISSUE-PLASMINOGEN ACTIVATOR PROTEASE WITH BENZAMIDINE-TYPE INHIBITORS - INTERFERENCE BY THE KRINGLE-2 MODULE

      Biochemistry
    40. STURZEBECHER J; MEIER J
      SYNTHETIC LOW-MOLECULAR-WEIGHT THROMBIN INHIBITORS - THE IDEAL ANTITHROMBOTIC DRUG - AN INTRODUCTION

      Journal of enzyme inhibition
    41. STURZEBECHER J; PRASA D; WIKSTROM P; VIEWEG H
      STRUCTURE-ACTIVITY-RELATIONSHIPS OF INHIBITORS DERIVED FROM 3-AMIDINOPHENYLALANINE

      Journal of enzyme inhibition
    42. BERGNER A; BAUER M; BRANDSTETTER H; STURZEBECHER J; BODE W
      THE X-RAY CRYSTAL-STRUCTURE OF THROMBIN IN COMPLEX WITH LFONYL-L-3-AMIDINO-PHENYLALANYL-4-METHYLPIPERIDIDE - THE BENEFICIAL EFFECT OF FILLING OUT AN EMPTY CAVITY

      Journal of enzyme inhibition
    43. STURZEBECHER J; WIKSTROM P; VIEWEQ H; STOCKER K
      INHIBITORS OF FIBRINOLYTIC ENZYMES OF THE 3-AMIDINOPHENYLALANINE-TYPE

      Thrombosis and haemostasis
    44. GLUSA E; STURZEBECHER J
      INHIBITION OF THROMBIN-INDUCED PLATELET ACTIVATION BY THROMBIN INHIBITORS OF THE BENZAMIDINE TYPE

      Thrombosis and haemostasis
    45. VERHALLEN PFJ; GEHRMANN G; PRASA D; STURZEBECHER J
      MEASUREMENT OF THROMBIN GENERATION IN HUMAN PLASMA BY 2 DIFFERENT METHODS (SUBSAMPLE CONTINUOUS) - CHARACTERIZATION OF DIFFERENT ANTICOAGULANTS

      Thrombosis and haemostasis
    46. PRASA D; SVENDSEN L; STURZEBECHER J
      THE ABILITY OF THROMBIN INHIBITORS TO NEUTRALIZE A THROMBIN PULSE GENERATED IN PLASMA

      Thrombosis and haemostasis
    47. STURZEBECHER J; PRASA D; WIKSTROM P; VIEWEG H; ADLER C; MEIER J
      POTENT THROMBIN INHIBITORS OF THE 3-AMIDINOPHENYL-ALANINE TYPE - PIPERAZIDES WITH IMPROVED BIOAVAILABILITY

      Thrombosis and haemostasis
    48. STURZEBECHER J; WIKSTROM P; VIEWEG H; SOMMERHOFF CP
      INHIBITION OF TRYPTASE BY BENZAMIDINES

      Journal of investigative dermatology
    49. STURZEBECHER J; PRASA D; WIKSTROM P; VIEWEG H
      NOVEL PLASMA KALLIKREIN INHIBITORS OF THE BENZAMIDINE TYPE

      Brazilian journal of medical and biological research
    50. BAUER M; BRANDSTETTER H; STURZEBECHER J; BODE W
      THE THROMBIN STRUCTURE AS A TOOL FOR THE RATIONAL DESIGN OF ANTITHROMBOTICS

      Thrombosis and haemostasis
    51. STURZEBECHER J; WIKSTROM P; VIEWEG H
      STRUCTURE-ACTIVITY-RELATIONSHIPS FOR INHIBITION OF THROMBIN BY 3-AMIDINOPHENYLALANINE DERIVATIVES

      Thrombosis and haemostasis
    52. STURZEBECHER J; STOCKER K; RICHTER M; GLUSA E
      INHIBITION OF THROMBOCYTIN BY BENZAMIDINE DERIVATIVES

      Thrombosis and haemostasis
    53. STURZEBECHER J; BRUGGENER E; PAINTZ M; MEIER J
      PHARMACOKINETICS, ANTICOAGULANT AND ANTITHROMBOTIC ACTION OF NOVEL BENZAMIDINE-DERIVED THROMBIN INHIBITORS

      Thrombosis and haemostasis
    54. BAUER M; BRANDSTETTER H; TURK D; STURZEBECHER J; BODE W
      CRYSTALLOGRAPHIC DETERMINATION OF THROMBIN COMPLEXES WITH SMALL SYNTHETIC INHIBITORS AS A STARTING POINT FOR THE RECEPTOR-BASED DESIGN OF ANTITHROMBOTICS

      Seminars in thrombosis and hemostasis


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/08/20 alle ore 22:17:36