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1. Dorfman, JR; Stefanova, I; Yasutomo, K; Germain, RN
   Class II essential for CD4 survival - Response
   NATURE IMMUNOLOGY
   
   J.R. Dorfman et al., "Class II essential for CD4 survival - Response", NAT IMMUNOL, 2(2), 2001, pp. 136-137
2. Delon, J; Kaibuchi, K; Germain, RN
   Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin
   IMMUNITY
   
   J. Delon et al., "Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin", IMMUNITY, 15(5), 2001, pp. 691-701
3. Delon, J; Germain, RN
   The immunological synapse: required for T cell receptor signalling or directing T cell effector function? Response
   CURRENT BIOLOGY
   
   J. Delon e R.N. Germain, "The immunological synapse: required for T cell receptor signalling or directing T cell effector function? Response", CURR BIOL, 11(8), 2001, pp. R290-R291
4. Germain, RN
   The art of the probable: System control in the adaptive immune system
   SCIENCE
   
   R.N. Germain, "The art of the probable: System control in the adaptive immune system", SCIENCE, 293(5528), 2001, pp. 240-245
5. Germain, RN
   The T cell receptor for antigen: Signaling and ligand discrimination
   JOURNAL OF BIOLOGICAL CHEMISTRY
   
   R.N. Germain, "The T cell receptor for antigen: Signaling and ligand discrimination", J BIOL CHEM, 276(38), 2001, pp. 35223-35226
6. Castellino, F; Han, R; Germain, RN
   The transmembrane segment of invariant chain mediates binding to MHC classII molecules in a CLIP-independent manner
   EUROPEAN JOURNAL OF IMMUNOLOGY
   
   F. Castellino et al., "The transmembrane segment of invariant chain mediates binding to MHC classII molecules in a CLIP-independent manner", EUR J IMMUN, 31(3), 2001, pp. 841-850
7. Dorfman, JR; Stefanova, I; Yasutomo, K; Germain, RN
   CD4(+) T cell survival is not directly linked to self-MHC-induced TCR signaling
   NATURE IMMUNOLOGY
   
   J.R. Dorfman et al., "CD4(+) T cell survival is not directly linked to self-MHC-induced TCR signaling", NAT IMMUNOL, 1(4), 2000, pp. 329-335
8. Lu, FWM; Yasutomo, K; Goodman, GB; McHeyzer-Williams, LJ; McHeyzer-Williams, MG; Germain, RN; Ashwell, JD
   Thymocyte resistance to glucocorticoids leads to antigen-specific unresponsiveness due to "holes" in the T cell repertoire
   IMMUNITY
   
   F.W.M. Lu et al., "Thymocyte resistance to glucocorticoids leads to antigen-specific unresponsiveness due to "holes" in the T cell repertoire", IMMUNITY, 12(2), 2000, pp. 183-192
9. Delon, J; Germain, RN
   Information transfer at the immunological synapse
   CURRENT BIOLOGY
   
   J. Delon e R.N. Germain, "Information transfer at the immunological synapse", CURR BIOL, 10(24), 2000, pp. R923-R933
10. Yasutomo, K; Doyle, C; Miele, L; Fuchs, C; Germain, RN
    The duration of antigen receptor signalling determines CD4(+) versus CD8(+) T-cell lineage fate (vol 404, pg 506, 2000)
    NATURE
    
    K. Yasutomo et al., "The duration of antigen receptor signalling determines CD4(+) versus CD8(+) T-cell lineage fate (vol 404, pg 506, 2000)", NATURE, 407(6800), 2000, pp. 110-110
11. Yasutomo, K; Doyle, C; Miele, L; Germain, RN
    The duration of antigen receptor signalling determines CD4(+) versus CD8(+) T-cell lineage fate
    NATURE
    
    K. Yasutomo et al., "The duration of antigen receptor signalling determines CD4(+) versus CD8(+) T-cell lineage fate", NATURE, 404(6777), 2000, pp. 506-510
12. Yasutomo, K; Lucas, B; Germain, RN
    TCR signaling for initiation and completion of thymocyte positive selection has distinct requirements for ligand quality and presenting cell type
    JOURNAL OF IMMUNOLOGY
    
    K. Yasutomo et al., "TCR signaling for initiation and completion of thymocyte positive selection has distinct requirements for ligand quality and presenting cell type", J IMMUNOL, 165(6), 2000, pp. 3015-3022
13. Lucas, B; Germain, RN
    Opening a window on thymic positive selection: Developmental changes in the influence of cosignaling by integrins and CD28 on selection events induced by TCR engagement
    JOURNAL OF IMMUNOLOGY
    
    B. Lucas e R.N. Germain, "Opening a window on thymic positive selection: Developmental changes in the influence of cosignaling by integrins and CD28 on selection events induced by TCR engagement", J IMMUNOL, 165(4), 2000, pp. 1889-1895
14. Inaba, K; Turley, S; Iyoda, T; Yamaide, F; Shimoyama, S; Sousa, CRE; Germain, RN; Mellman, I; Steinman, RM
    The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli
    JOURNAL OF EXPERIMENTAL MEDICINE
    
    K. Inaba et al., "The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli", J EXP MED, 191(6), 2000, pp. 927-936
15. Castellino, F; Boucher, PE; Eichelberg, K; Mayhew, M; Rothman, JE; Houghton, AN; Germain, RN
    Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways
    JOURNAL OF EXPERIMENTAL MEDICINE
    
    F. Castellino et al., "Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways", J EXP MED, 191(11), 2000, pp. 1957-1964
16. Dittel, BN; Stefanova, I; Germain, RN; Janeway, CA
    Cross-antagonism of a T cell clone expressing two distinct T cell receptors
    IMMUNITY
    
    B.N. Dittel et al., "Cross-antagonism of a T cell clone expressing two distinct T cell receptors", IMMUNITY, 11(3), 1999, pp. 289-298
17. Lucas, B; Stefanova, I; Yasutomo, K; Dautigny, N; Germain, RN
    Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire
    IMMUNITY
    
    B. Lucas et al., "Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire", IMMUNITY, 10(3), 1999, pp. 367-376
18. Germain, RN; Stefanova, I
    The dynamics of T cell receptor signaling: Complex orchestration and the key roles of tempo and cooperation
    ANNUAL REVIEW OF IMMUNOLOGY
    
    R.N. Germain e I. Stefanova, "The dynamics of T cell receptor signaling: Complex orchestration and the key roles of tempo and cooperation", ANN R IMMUN, 17, 1999, pp. 467-522
19. Itoh, Y; Hemmer, B; Martin, R; Germain, RN
    Serial TCR engagement and down-modulation by peptide : MHC molecule ligands: Relationship to the quality of individual TCR signaling events
    JOURNAL OF IMMUNOLOGY
    
    Y. Itoh et al., "Serial TCR engagement and down-modulation by peptide : MHC molecule ligands: Relationship to the quality of individual TCR signaling events", J IMMUNOL, 162(4), 1999, pp. 2073-2080
20. Sousa, CRE; Germain, RN
    Analysis of adjuvant function by direct visualization of antigen presentation in vivo: Endotoxin promotes accumulation of antigen-bearing dendritic cells in the T cell areas of lymphoid tissue
    JOURNAL OF IMMUNOLOGY
    
    C.R.E. Sousa e R.N. Germain, "Analysis of adjuvant function by direct visualization of antigen presentation in vivo: Endotoxin promotes accumulation of antigen-bearing dendritic cells in the T cell areas of lymphoid tissue", J IMMUNOL, 162(11), 1999, pp. 6552-6561
21. SANTANGELO DB; LUCAS B; WATERBURY PG; COHEN B; BRABB T; GOVERMAN J; GERMAIN RN; JANEWAY CA
    A MOLECULAR MAP OF T-CELL DEVELOPMENT
    Immunity (Cambridge, Mass.)
    
    D.B. Santangelo et al., "A MOLECULAR MAP OF T-CELL DEVELOPMENT", Immunity (Cambridge, Mass.), 9(2), 1998, pp. 179-186
22. SANTANGELO DB; LUCAS B; WATERBURY G; COHEN B; BRABB T; GOVERMAN J; GERMAIN RN; JANEWAY CA
    A DEVELOPMENTAL MAP OF THYMOCYTE SELECTION
    The FASEB journal
    
    D.B. Santangelo et al., "A DEVELOPMENTAL MAP OF THYMOCYTE SELECTION", The FASEB journal, 12(4), 1998, pp. 1778-1778
23. NATARAJAN K; CASTELLINO F; GERMAIN RN; MARGULIES DH
    THE ZEBRAFISH INVARIANT CHAIN ASSEMBLES WITH MURINE I-A(D)
    The FASEB journal
    
    K. Natarajan et al., "THE ZEBRAFISH INVARIANT CHAIN ASSEMBLES WITH MURINE I-A(D)", The FASEB journal, 12(4), 1998, pp. 3415-3415
24. CASTELLINO F; ZAPPACOSTA F; COLIGAN JE; GERMAIN RN
    LARGE PROTEIN-FRAGMENTS AS SUBSTRATES FOR ENDOCYTIC ANTIGEN CAPTURE BY MHC CLASS-II MOLECULES
    The Journal of immunology (1950)
    
    F. Castellino et al., "LARGE PROTEIN-FRAGMENTS AS SUBSTRATES FOR ENDOCYTIC ANTIGEN CAPTURE BY MHC CLASS-II MOLECULES", The Journal of immunology (1950), 161(8), 1998, pp. 4048-4057
25. HEMMER B; STEFANOVA I; VERGELLI M; GERMAIN RN; MARTIN R
    RELATIONSHIPS AMONG TCR LIGAND POTENCY, THRESHOLDS FOR EFFECTOR FUNCTION ELICITATION, AND THE QUALITY OF EARLY SIGNALING EVENTS IN HUMAN T-CELLS
    The Journal of immunology
    
    B. Hemmer et al., "RELATIONSHIPS AMONG TCR LIGAND POTENCY, THRESHOLDS FOR EFFECTOR FUNCTION ELICITATION, AND THE QUALITY OF EARLY SIGNALING EVENTS IN HUMAN T-CELLS", The Journal of immunology, 160(12), 1998, pp. 5807-5814
26. KIM MG; CHEN C; FLOMERFELT FA; GERMAIN RN; SCHWARTZ RH
    A SUBTRACTIVE PCR-BASED CDNA LIBRARY MADE FROM FETAL THYMIC STROMAL CELLS
    Journal of immunological methods
    
    M.G. Kim et al., "A SUBTRACTIVE PCR-BASED CDNA LIBRARY MADE FROM FETAL THYMIC STROMAL CELLS", Journal of immunological methods, 213(2), 1998, pp. 169-182
27. PORGADOR A; IRVINE KR; IWASAKI A; BARBER BH; RESTIFO NP; GERMAIN RN
    PREDOMINANT ROLE FOR DIRECTLY TRANSFECTED DENDRITIC CELLS IN ANTIGEN PRESENTATION TO CD8(+)T CELLS AFTER GENE GUN IMMUNIZATION
    The Journal of experimental medicine
    
    A. Porgador et al., "PREDOMINANT ROLE FOR DIRECTLY TRANSFECTED DENDRITIC CELLS IN ANTIGEN PRESENTATION TO CD8(+)T CELLS AFTER GENE GUN IMMUNIZATION", The Journal of experimental medicine, 188(6), 1998, pp. 1075-1082
28. COMBADIERE B; SOUSA CRE; GERMAIN RN; LENARDO MJ
    SELECTIVE INDUCTION OF APOPTOSIS IN MATURE T-LYMPHOCYTES BY VARIANT T-CELL RECEPTOR LIGANDS
    The Journal of experimental medicine
    
    B. Combadiere et al., "SELECTIVE INDUCTION OF APOPTOSIS IN MATURE T-LYMPHOCYTES BY VARIANT T-CELL RECEPTOR LIGANDS", The Journal of experimental medicine, 187(3), 1998, pp. 349-355
29. PORGADOR A; YEWDELL JW; DENG YP; BENNINK JR; GERMAIN RN
    LOCALIZATION, QUANTITATION, AND IN-SITU DETECTION OF SPECIFIC PEPTIDEMHC CLASS-I COMPLEXES USING A MONOCLONAL-ANTIBODY
    Immunity
    
    A. Porgador et al., "LOCALIZATION, QUANTITATION, AND IN-SITU DETECTION OF SPECIFIC PEPTIDEMHC CLASS-I COMPLEXES USING A MONOCLONAL-ANTIBODY", Immunity, 6(6), 1997, pp. 715-726
30. GERMAIN RN
    T-CELL SIGNALING - THE IMPORTANCE OF RECEPTOR CLUSTERING
    Current biology
    
    R.N. Germain, "T-CELL SIGNALING - THE IMPORTANCE OF RECEPTOR CLUSTERING", Current biology, 7(10), 1997, pp. 640-644
31. CASTELLINO F; ZHONG GM; GERMAIN RN
    ANTIGEN PRESENTATION BY MHC CLASS-II MOLECULES - INVARIANT CHAIN FUNCTION, PROTEIN TRAFFICKING, AND THE MOLECULAR-BASIS OF DIVERSE DETERMINANT CAPTURE
    Human immunology
    
    F. Castellino et al., "ANTIGEN PRESENTATION BY MHC CLASS-II MOLECULES - INVARIANT CHAIN FUNCTION, PROTEIN TRAFFICKING, AND THE MOLECULAR-BASIS OF DIVERSE DETERMINANT CAPTURE", Human immunology, 54(2), 1997, pp. 159-169
32. PORGADOR A; GERMAIN RN
    MONOCLONAL-ANTIBODY DETECTION OF SPECIFIC CELL-BOUND PEPTIDE-MHC CLASS-I COMPLEXES WITH A SENSITIVITY APPROACHING CD8-CELLS( T)
    Journal of allergy and clinical immunology
    
    A. Porgador e R.N. Germain, "MONOCLONAL-ANTIBODY DETECTION OF SPECIFIC CELL-BOUND PEPTIDE-MHC CLASS-I COMPLEXES WITH A SENSITIVITY APPROACHING CD8-CELLS( T)", Journal of allergy and clinical immunology, 99(1), 1997, pp. 472-472
33. ITOH Y; GERMAIN RN
    CELL RESPONSE THRESHOLD AND RESPONSE HIERARCHY ANALYZED AT THE SINGLE-CELL LEVEL
    Journal of allergy and clinical immunology
    
    Y. Itoh e R.N. Germain, "CELL RESPONSE THRESHOLD AND RESPONSE HIERARCHY ANALYZED AT THE SINGLE-CELL LEVEL", Journal of allergy and clinical immunology, 99(1), 1997, pp. 818-818
34. MARTIN R; STEPHANOVA I; VERGELLI M; GERMAIN RN; HEMMER B
    COMPARISON OF EFFECTOR FUNCTIONS AND EARLY SIGNALING EVENTS IN HUMAN CD4-CELLS( T)
    Journal of allergy and clinical immunology
    
    R. Martin et al., "COMPARISON OF EFFECTOR FUNCTIONS AND EARLY SIGNALING EVENTS IN HUMAN CD4-CELLS( T)", Journal of allergy and clinical immunology, 99(1), 1997, pp. 1026-1026
35. CASTELLINO F; ZAPPACOSTA F; GERMAIN RN
    IDENTIFICATION OF LARGE PROTEIN-FRAGMENTS AS A SUBSTRATE FOR ANTIGEN CAPTURE BY MHC CLASS-II MOLECULES
    Journal of allergy and clinical immunology
    
    F. Castellino et al., "IDENTIFICATION OF LARGE PROTEIN-FRAGMENTS AS A SUBSTRATE FOR ANTIGEN CAPTURE BY MHC CLASS-II MOLECULES", Journal of allergy and clinical immunology, 99(1), 1997, pp. 1505-1505
36. ZHONG GM; SOUSA CRE; GERMAIN RN
    PRODUCTION, SPECIFICITY, AND FUNCTIONALITY OF MONOCLONAL-ANTIBODIES TO SPECIFIC PEPTIDE-MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II COMPLEXESFORMED BY PROCESSING OF EXOGENOUS PROTEIN
    Proceedings of the National Academy of Sciences of the United Statesof America
    
    G.M. Zhong et al., "PRODUCTION, SPECIFICITY, AND FUNCTIONALITY OF MONOCLONAL-ANTIBODIES TO SPECIFIC PEPTIDE-MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II COMPLEXESFORMED BY PROCESSING OF EXOGENOUS PROTEIN", Proceedings of the National Academy of Sciences of the United Statesof America, 94(25), 1997, pp. 13856-13861
37. DAY PM; YEWDELL JW; PORGADOR A; GERMAIN RN; BENNINK JR
    DIRECT DELIVERY OF EXOGENOUS MHC CLASS-I MOLECULE-BINDING OLIGOPEPTIDES TO THE ENDOPLASMIC-RETICULUM OF VIABLE CELLS
    Proceedings of the National Academy of Sciences of the United Statesof America
    
    P.M. Day et al., "DIRECT DELIVERY OF EXOGENOUS MHC CLASS-I MOLECULE-BINDING OLIGOPEPTIDES TO THE ENDOPLASMIC-RETICULUM OF VIABLE CELLS", Proceedings of the National Academy of Sciences of the United Statesof America, 94(15), 1997, pp. 8064-8069
38. ZHONG GM; SOUSA CRE; GERMAIN RN
    ANTIGEN-UNSPECIFIC B-CELLS AND LYMPHOID DENDRITIC CELLS BOTH SHOW EXTENSIVE SURFACE EXPRESSION OF PROCESSED ANTIGEN-MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II COMPLEXES AFTER SOLUBLE-PROTEIN EXPOSURE IN-VIVO ORIN-VITRO
    The Journal of experimental medicine
    
    G.M. Zhong et al., "ANTIGEN-UNSPECIFIC B-CELLS AND LYMPHOID DENDRITIC CELLS BOTH SHOW EXTENSIVE SURFACE EXPRESSION OF PROCESSED ANTIGEN-MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II COMPLEXES AFTER SOLUBLE-PROTEIN EXPOSURE IN-VIVO ORIN-VITRO", The Journal of experimental medicine, 186(5), 1997, pp. 673-682
39. ITOH Y; GERMAIN RN
    SINGLE-CELL ANALYSIS REVEALS REGULATED HIERARCHICAL T-CELL ANTIGEN RECEPTOR SIGNALING THRESHOLDS AND INTRACLONAL HETEROGENEITY FOR INDIVIDUAL CYTOKINE RESPONSES OF CD4(-CELLS() T)
    The Journal of experimental medicine
    
    Y. Itoh e R.N. Germain, "SINGLE-CELL ANALYSIS REVEALS REGULATED HIERARCHICAL T-CELL ANTIGEN RECEPTOR SIGNALING THRESHOLDS AND INTRACLONAL HETEROGENEITY FOR INDIVIDUAL CYTOKINE RESPONSES OF CD4(-CELLS() T)", The Journal of experimental medicine, 186(5), 1997, pp. 757-766
40. SOUSA CRE; HIENY S; SCHARTONKERSTEN T; JANKOVIC D; CHAREST H; GERMAIN RN; SHER A
    IN-VIVO MICROBIAL STIMULATION INDUCES RAPID CD40 LIGAND-INDEPENDENT PRODUCTION OF INTERLEUKIN-12 BY DENDRITIC CELLS AND THEIR REDISTRIBUTION TO T-CELL AREAS
    The Journal of experimental medicine
    
    C.R.E. Sousa et al., "IN-VIVO MICROBIAL STIMULATION INDUCES RAPID CD40 LIGAND-INDEPENDENT PRODUCTION OF INTERLEUKIN-12 BY DENDRITIC CELLS AND THEIR REDISTRIBUTION TO T-CELL AREAS", The Journal of experimental medicine, 186(11), 1997, pp. 1819-1829
41. VANMEERWIJK JPM; MARGUERAT S; LEES RK; GERMAIN RN; FOWLKES BJ; MACDONALD HR
    QUANTITATIVE IMPACT OF THYMIC CLONAL DELETION ON THE T-CELL REPERTOIRE
    The Journal of experimental medicine
    
    J.P.M. Vanmeerwijk et al., "QUANTITATIVE IMPACT OF THYMIC CLONAL DELETION ON THE T-CELL REPERTOIRE", The Journal of experimental medicine, 185(3), 1997, pp. 377-383
42. ZHONG GM; ROMAGNOLI P; GERMAIN RN
    RELATED LEUCINE-BASED CYTOPLASMIC TARGETING SIGNALS IN INVARIANT CHAIN AND MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II MOLECULES CONTROL ENDOCYTIC PRESENTATION OF DISTINCT DETERMINANTS IN A SINGLE PROTEIN
    The Journal of experimental medicine
    
    G.M. Zhong et al., "RELATED LEUCINE-BASED CYTOPLASMIC TARGETING SIGNALS IN INVARIANT CHAIN AND MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II MOLECULES CONTROL ENDOCYTIC PRESENTATION OF DISTINCT DETERMINANTS IN A SINGLE PROTEIN", The Journal of experimental medicine, 185(3), 1997, pp. 429-438
43. MADRENAS J; CHAU LA; SMITH J; BLUESTONE JA; GERMAIN RN
    THE EFFICIENCY OF CD4 RECRUITMENT TO LIGAND-ENGAGED TCR CONTROLS THE AGONIST PARTIAL AGONIST PROPERTIES OF PEPTIDE-MHC MOLECULE LIGANDS/
    The Journal of experimental medicine
    
    J. Madrenas et al., "THE EFFICIENCY OF CD4 RECRUITMENT TO LIGAND-ENGAGED TCR CONTROLS THE AGONIST PARTIAL AGONIST PROPERTIES OF PEPTIDE-MHC MOLECULE LIGANDS/", The Journal of experimental medicine, 185(2), 1997, pp. 219-229
44. LUCAS B; GERMAIN RN
    UNEXPECTEDLY COMPLEX REGULATION OF CD4 CD8 CORECEPTOR EXPRESSION SUPPORTS A REVISED MODEL FOR CD4(+)CD8(+) THYMOCYTE DIFFERENTIATION/
    Immunity
    
    B. Lucas e R.N. Germain, "UNEXPECTEDLY COMPLEX REGULATION OF CD4 CD8 CORECEPTOR EXPRESSION SUPPORTS A REVISED MODEL FOR CD4(+)CD8(+) THYMOCYTE DIFFERENTIATION/", Immunity, 5(5), 1996, pp. 461-477
45. LUCAS B; GERMAIN RN
    T-CELL REPERTOIRE - POLITICAL CORRECTNESS IN THE IMMUNE-SYSTEM
    Current biology
    
    B. Lucas e R.N. Germain, "T-CELL REPERTOIRE - POLITICAL CORRECTNESS IN THE IMMUNE-SYSTEM", Current biology, 6(7), 1996, pp. 783-787
46. HUANG LY; VANMEERWIJK JPM; BIKOFF EK; GERMAIN RN
    COMPARISON OF THYMOCYTE DEVELOPMENT IN NORMAL AND INVARIANT CHAIN-DEFICIENT MICE PROVIDES EVIDENCE THAT MATURATION-RELATED CHANGES IN TCR AND CORECEPTOR LEVELS PLAY A CRITICAL ROLE IN CELL FATE
    International immunology
    
    L.Y. Huang et al., "COMPARISON OF THYMOCYTE DEVELOPMENT IN NORMAL AND INVARIANT CHAIN-DEFICIENT MICE PROVIDES EVIDENCE THAT MATURATION-RELATED CHANGES IN TCR AND CORECEPTOR LEVELS PLAY A CRITICAL ROLE IN CELL FATE", International immunology, 8(9), 1996, pp. 1429-1440
47. GERMAIN RN; CASTELLINO F; HAN RC; SOUSA CR; ROMAGNOLI P; SADEGHNASSERI S; ZHONG GM
    PROCESSING AND PRESENTATION OF ENDOCYTICALLY ACQUIRED PROTEIN ANTIGENS BY MHC CLASS-II AND CLASS-I MOLECULES
    Immunological reviews
    
    R.N. Germain et al., "PROCESSING AND PRESENTATION OF ENDOCYTICALLY ACQUIRED PROTEIN ANTIGENS BY MHC CLASS-II AND CLASS-I MOLECULES", Immunological reviews, 151, 1996, pp. 5-30
48. MADRENAS J; SCHWARTZ RH; GERMAIN RN
    INTERLEUKIN-2 PRODUCTION, NOT THE PATTERN OF EARLY T-CELL ANTIGEN RECEPTOR-DEPENDENT TYROSINE PHOSPHORYLATION, CONTROLS ANERGY INDUCTION BYBOTH AGONISTS AND PARTIAL AGONISTS
    Proceedings of the National Academy of Sciences of the United Statesof America
    
    J. Madrenas et al., "INTERLEUKIN-2 PRODUCTION, NOT THE PATTERN OF EARLY T-CELL ANTIGEN RECEPTOR-DEPENDENT TYROSINE PHOSPHORYLATION, CONTROLS ANERGY INDUCTION BYBOTH AGONISTS AND PARTIAL AGONISTS", Proceedings of the National Academy of Sciences of the United Statesof America, 93(18), 1996, pp. 9736-9741
49. SHEN XL; HU B; MCPHIE P; WU XH; FOX A; GERMAIN RN; KONIG R
    PEPTIDES CORRESPONDING TO CD4-INTERACTING REGIONS OF MURINE MWC CLASS-II MOLECULES MODULATE IMMUNE-RESPONSES OF CD4(-LYMPHOCYTES IN-VITRO AND IN-VIVO() T)
    The Journal of immunology
    
    X.L. Shen et al., "PEPTIDES CORRESPONDING TO CD4-INTERACTING REGIONS OF MURINE MWC CLASS-II MOLECULES MODULATE IMMUNE-RESPONSES OF CD4(-LYMPHOCYTES IN-VITRO AND IN-VIVO() T)", The Journal of immunology, 157(1), 1996, pp. 87-100
50. ZHONG GM; CASTELLINO F; ROMAGNOLI P; GERMAIN RN
    EVIDENCE THAT BINDING-SITE OCCUPANCY IS NECESSARY AND SUFFICIENT FOR EFFECTIVE MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS-II TRANSPORT THROUGH THE SECRETORY PATHWAY REDEFINES THE PRIMARY FUNCTION OF CLASS II-ASSOCIATED INVARIANT CHAIN PEPTIDES (CLIP)
    The Journal of experimental medicine
    
    G.M. Zhong et al., "EVIDENCE THAT BINDING-SITE OCCUPANCY IS NECESSARY AND SUFFICIENT FOR EFFECTIVE MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS-II TRANSPORT THROUGH THE SECRETORY PATHWAY REDEFINES THE PRIMARY FUNCTION OF CLASS II-ASSOCIATED INVARIANT CHAIN PEPTIDES (CLIP)", The Journal of experimental medicine, 184(5), 1996, pp. 2061-2066
51. SOUSA CRE; LEVINE EH; GERMAIN RN
    PARTIAL SIGNALING BY CD8(-CELLS IN RESPONSE TO ANTAGONIST LIGANDS() T)
    The Journal of experimental medicine
    
    C.R.E. Sousa et al., "PARTIAL SIGNALING BY CD8(-CELLS IN RESPONSE TO ANTAGONIST LIGANDS() T)", The Journal of experimental medicine, 184(1), 1996, pp. 149-157
52. BIKOFF EK; GERMAIN RN; ROBERTSON EJ
    ALLELIC DIFFERENCES AFFECTING INVARIANT CHAIN DEPENDENCY OF MHC CLASS-II SUBUNIT ASSEMBLY
    Immunity
    
    E.K. Bikoff et al., "ALLELIC DIFFERENCES AFFECTING INVARIANT CHAIN DEPENDENCY OF MHC CLASS-II SUBUNIT ASSEMBLY", Immunity, 2(3), 1995, pp. 301-310
53. CASTELLINO F; GERMAIN RN
    EXTENSIVE TRAFFICKING OF MHC CLASS II-INVARIANT CHAIN COMPLEXES IN THE ENDOCYTIC PATHWAY AND APPEARANCE OF PEPTIDE-LOADED CLASS-II IN MULTIPLE COMPARTMENTS
    Immunity
    
    F. Castellino e R.N. Germain, "EXTENSIVE TRAFFICKING OF MHC CLASS II-INVARIANT CHAIN COMPLEXES IN THE ENDOCYTIC PATHWAY AND APPEARANCE OF PEPTIDE-LOADED CLASS-II IN MULTIPLE COMPARTMENTS", Immunity, 2(1), 1995, pp. 73-88
54. MADRENAS J; SCHWARTZ RH; GERMAIN RN
    T-CELL ANERGY IS NOT DETERMINED BY THE PATTERN OF EARLY TCR SIGNALS
    Journal of the American Society of Nephrology
    
    J. Madrenas et al., "T-CELL ANERGY IS NOT DETERMINED BY THE PATTERN OF EARLY TCR SIGNALS", Journal of the American Society of Nephrology, 6(3), 1995, pp. 840-840
55. GERMAIN RN; CASTELLINO F; ROMAGNOLI P; MADRENAS J; WANGE R; ISAKOV N; SAMELSON LE
    FORMATION AND FUNCTION OF PEPTIDE - MHC MOLECULE LIGANDS FOR THE TCR
    Journal of cellular biochemistry
    
    R.N. Germain et al., "FORMATION AND FUNCTION OF PEPTIDE - MHC MOLECULE LIGANDS FOR THE TCR", Journal of cellular biochemistry, 1995, pp. 4-4
56. MADRENAS J; WANGE RL; WANG JL; ISAKOV N; SAMELSON LE; GERMAIN RN
    ZETA-PHOSPHORYLATION WITHOUT ZAP-70 ACTIVATION-INDUCED BY TCR ANTAGONISTS OR PARTIAL AGONISTS
    Science
    
    J. Madrenas et al., "ZETA-PHOSPHORYLATION WITHOUT ZAP-70 ACTIVATION-INDUCED BY TCR ANTAGONISTS OR PARTIAL AGONISTS", Science, 267(5197), 1995, pp. 515-518
57. VANMEERWIJK JPM; OCONNELL EM; GERMAIN RN
    EVIDENCE FOR LINEAGE COMMITMENT AND INITIATION OF POSITIVE SELECTION BY THYMOCYTES WITH INTERMEDIATE SURFACE PHENOTYPES
    The Journal of immunology
    
    J.P.M. Vanmeerwijk et al., "EVIDENCE FOR LINEAGE COMMITMENT AND INITIATION OF POSITIVE SELECTION BY THYMOCYTES WITH INTERMEDIATE SURFACE PHENOTYPES", The Journal of immunology, 154(12), 1995, pp. 6314-6323
58. ROMAGNOLI P; GERMAIN RN
    INHIBITION OF INVARIANT CHAIN-(II)-CALNEXIN INTERACTION RESULTS IN ENHANCED DEGRADATION OF II BUT DOES NOT PREVENT THE ASSEMBLY OF ALPHA-BETA-II COMPLEXES
    The Journal of experimental medicine
    
    P. Romagnoli e R.N. Germain, "INHIBITION OF INVARIANT CHAIN-(II)-CALNEXIN INTERACTION RESULTS IN ENHANCED DEGRADATION OF II BUT DOES NOT PREVENT THE ASSEMBLY OF ALPHA-BETA-II COMPLEXES", The Journal of experimental medicine, 182(6), 1995, pp. 2027-2036
59. KONIG R; SHEN XL; GERMAIN RN
    INVOLVEMENT OF BOTH MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II ALPHA-CHAINS AND BETA-CHAINS IN CD4 FUNCTION INDICATES A ROLE FOR ORDERED OLIGOMERIZATION IN T-CELL ACTIVATION
    The Journal of experimental medicine
    
    R. Konig et al., "INVOLVEMENT OF BOTH MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II ALPHA-CHAINS AND BETA-CHAINS IN CD4 FUNCTION INDICATES A ROLE FOR ORDERED OLIGOMERIZATION IN T-CELL ACTIVATION", The Journal of experimental medicine, 182(3), 1995, pp. 779-787
60. SOUSA CRE; GERMAIN RN
    MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I PRESENTATION OF PEPTIDES DERIVED FROM SOLUBLE EXOGENOUS ANTIGEN BY A SUBSET OF CELLS ENGAGED IN PHAGOCYTOSIS
    The Journal of experimental medicine
    
    C.R.E. Sousa e R.N. Germain, "MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I PRESENTATION OF PEPTIDES DERIVED FROM SOLUBLE EXOGENOUS ANTIGEN BY A SUBSET OF CELLS ENGAGED IN PHAGOCYTOSIS", The Journal of experimental medicine, 182(3), 1995, pp. 841-851
61. MARKS MS; GERMAIN RN; BONIFACINO JS
    TRANSIENT AGGREGATION OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II CHAINS DURING ASSEMBLY IN NORMAL SPLEEN-CELLS
    The Journal of biological chemistry
    
    M.S. Marks et al., "TRANSIENT AGGREGATION OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II CHAINS DURING ASSEMBLY IN NORMAL SPLEEN-CELLS", The Journal of biological chemistry, 270(18), 1995, pp. 10475-10481
62. GERMAIN RN; CASTELLINO F; RINKER AG; SADEGHNASSERI S; ROMAGNOLI P
    THE BIOCHEMISTRY AND CELL BIOLOGY OF MHC CLASS-II ANTIGEN PRESENTATION
    Journal of cellular biochemistry
    
    R.N. Germain et al., "THE BIOCHEMISTRY AND CELL BIOLOGY OF MHC CLASS-II ANTIGEN PRESENTATION", Journal of cellular biochemistry, 1994, pp. 286-286
63. BONNEROT C; MARKS MS; COSSON P; ROBERTSON EJ; BIKOFF EK; GERMAIN RN; BONIFACINO JS
    ASSOCIATION WITH BIP AND AGGREGATION OF CLASS-II MCH MOLECULES SYNTHESIZED IN THE ABSENCE OF INVARIANT CHAIN
    EMBO journal
    
    C. Bonnerot et al., "ASSOCIATION WITH BIP AND AGGREGATION OF CLASS-II MCH MOLECULES SYNTHESIZED IN THE ABSENCE OF INVARIANT CHAIN", EMBO journal, 13(4), 1994, pp. 934-944
64. GERMAIN RN
    MHC-DEPENDENT ANTIGEN-PROCESSING AND PEPTIDE PRESENTATION - PROVIDINGLIGANDS FOR T-LYMPHOCYTE ACTIVATION
    Cell
    
    R.N. Germain, "MHC-DEPENDENT ANTIGEN-PROCESSING AND PEPTIDE PRESENTATION - PROVIDINGLIGANDS FOR T-LYMPHOCYTE ACTIVATION", Cell, 76(2), 1994, pp. 287-299
65. SADEGHNASSERI S; STERN LJ; WILEY DC; GERMAIN RN
    MHC CLASS-II FUNCTION PRESERVED BY LOW-AFFINITY PEPTIDE INTERACTIONS PRECEDING STABLE BINDING
    Nature
    
    S. Sadeghnasseri et al., "MHC CLASS-II FUNCTION PRESERVED BY LOW-AFFINITY PEPTIDE INTERACTIONS PRECEDING STABLE BINDING", Nature, 370(6491), 1994, pp. 647-650
66. JARVIS CD; GERMAIN RN; HAGER GL; DAMSCHRODER M; MATIS LA
    TISSUE-SPECIFIC EXPRESSION OF MESSENGER-RNAS ENCODING ENDOGENOUS VIRAL SUPERANTIGENS
    The Journal of immunology
    
    C.D. Jarvis et al., "TISSUE-SPECIFIC EXPRESSION OF MESSENGER-RNAS ENCODING ENDOGENOUS VIRAL SUPERANTIGENS", The Journal of immunology, 152(3), 1994, pp. 1032-1038
67. ROMAGNOLI P; GERMAIN RN
    THE CLIP REGION OF INVARIANT CHAIN PLAYS A CRITICAL ROLE IN REGULATING MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II FOLDING, TRANSPORT, AND PEPTIDE OCCUPANCY
    The Journal of experimental medicine
    
    P. Romagnoli e R.N. Germain, "THE CLIP REGION OF INVARIANT CHAIN PLAYS A CRITICAL ROLE IN REGULATING MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II FOLDING, TRANSPORT, AND PEPTIDE OCCUPANCY", The Journal of experimental medicine, 180(3), 1994, pp. 1107-1113
68. SEDER RA; GERMAIN RN; LINSLEY PS; PAUL WE
    CD28-MEDIATED COSTIMULATION OF INTERLEUKIN-2 (IL-2) PRODUCTION PLAYS A CRITICAL ROLE IN T-CELL PRIMING FOR IL-4 AND INTERFERON-GAMMA PRODUCTION
    The Journal of experimental medicine
    
    R.A. Seder et al., "CD28-MEDIATED COSTIMULATION OF INTERLEUKIN-2 (IL-2) PRODUCTION PLAYS A CRITICAL ROLE IN T-CELL PRIMING FOR IL-4 AND INTERFERON-GAMMA PRODUCTION", The Journal of experimental medicine, 179(1), 1994, pp. 299-304
69. GERMAIN RN
    SEEING DOUBLE
    Current biology
    
    R.N. Germain, "SEEING DOUBLE", Current biology, 3(9), 1993, pp. 586-589
70. BERZOFSKY JA; SHIRAI M; NAKAGAWA Y; PENDLETON CD; HOUGHTEN RA; YOKOMURO K; GERMAIN RN; TAKAHASHI H
    PROMISCUITY FOR MHC AND INDUCTION OF BROAD CROSS-REACTIVITY FOR HIV-1ISOLATES OF A DOMINANT CTL DETERMINANT OF THE HIV-1 ENVELOPE
    Journal of acquired immune deficiency syndromes
    
    J.A. Berzofsky et al., "PROMISCUITY FOR MHC AND INDUCTION OF BROAD CROSS-REACTIVITY FOR HIV-1ISOLATES OF A DOMINANT CTL DETERMINANT OF THE HIV-1 ENVELOPE", Journal of acquired immune deficiency syndromes, 6(6), 1993, pp. 678-678
71. GERMAIN RN
    PEPTIDE BINDING, CONFORMATIONAL-CHANGES, AND INTRACELLULAR-TRANSPORT IN THE MHC CLASS-I AND CLASS-II PRESENTATION PATHWAYS
    Journal of acquired immune deficiency syndromes
    
    R.N. Germain, "PEPTIDE BINDING, CONFORMATIONAL-CHANGES, AND INTRACELLULAR-TRANSPORT IN THE MHC CLASS-I AND CLASS-II PRESENTATION PATHWAYS", Journal of acquired immune deficiency syndromes, 6(6), 1993, pp. 734-734
72. HAHN WC; MENZIN E; SAITO T; GERMAIN RN; BIERER BE
    THE COMPLETE SEQUENCES OF PLASMIDS PFNEO AND PMH-NEO - CONVENIENT EXPRESSION VECTORS FOR HIGH-LEVEL EXPRESSION OF EUKARYOTIC GENES IN HEMATOPOIETIC-CELL LINES
    Gene
    
    W.C. Hahn et al., "THE COMPLETE SEQUENCES OF PLASMIDS PFNEO AND PMH-NEO - CONVENIENT EXPRESSION VECTORS FOR HIGH-LEVEL EXPRESSION OF EUKARYOTIC GENES IN HEMATOPOIETIC-CELL LINES", Gene, 127(2), 1993, pp. 267-268
73. VANMEERWIJK JPM; GERMAIN RN
    DEVELOPMENT OF MATURE CD8- SELECTION RATHER THAN INSTRUCTION( THYMOCYTES )
    Science
    
    J.P.M. Vanmeerwijk e R.N. Germain, "DEVELOPMENT OF MATURE CD8- SELECTION RATHER THAN INSTRUCTION( THYMOCYTES )", Science, 261(5123), 1993, pp. 911-915
74. GERMAIN RN; RINKER AG
    PEPTIDE BINDING INHIBITS PROTEIN AGGREGATION OF INVARIANT-CHAIN FREE CLASS-II DIMERS AND PROMOTES SURFACE EXPRESSION OF OCCUPIED MOLECULES
    Nature
    
    R.N. Germain e A.G. Rinker, "PEPTIDE BINDING INHIBITS PROTEIN AGGREGATION OF INVARIANT-CHAIN FREE CLASS-II DIMERS AND PROMOTES SURFACE EXPRESSION OF OCCUPIED MOLECULES", Nature, 363(6431), 1993, pp. 725-728
75. DING L; LINSLEY PS; HUANG LY; GERMAIN RN; SHEVACH EM
    IL-10 INHIBITS MACROPHAGE COSTIMULATORY ACTIVITY BY SELECTIVELY INHIBITING THE UP-REGULATION OF B7 EXPRESSION
    The Journal of immunology
    
    L. Ding et al., "IL-10 INHIBITS MACROPHAGE COSTIMULATORY ACTIVITY BY SELECTIVELY INHIBITING THE UP-REGULATION OF B7 EXPRESSION", The Journal of immunology, 151(3), 1993, pp. 1224-1234
76. DING L; LINSLEY PS; HUANG LY; GERMAIN RN; SHEVACH EM
    IL-10 INHIBITS MACROPHAGE (M0) COSTIMULATORY ACTIVITY BY SELECTIVELY INHIBITING THE UP-REGULATION OF B7 EXPRESSION
    The Journal of immunology
    
    L. Ding et al., "IL-10 INHIBITS MACROPHAGE (M0) COSTIMULATORY ACTIVITY BY SELECTIVELY INHIBITING THE UP-REGULATION OF B7 EXPRESSION", The Journal of immunology, 150(8), 1993, pp. 180-180
77. SEDER RA; GERMAIN RN; LINSLEY PS; PAUL WE
    PRIMING FOR LYMPHOKINE PRODUCTION CAN BE ACHIEVED IN THE ABSENCE OF B7 CD28 CO-STIMULATION IF IL-2 IS PRESENT/
    The Journal of immunology
    
    R.A. Seder et al., "PRIMING FOR LYMPHOKINE PRODUCTION CAN BE ACHIEVED IN THE ABSENCE OF B7 CD28 CO-STIMULATION IF IL-2 IS PRESENT/", The Journal of immunology, 150(8), 1993, pp. 252-252
78. BIKOFF EK; HUANG LY; EPISKOPOU V; VANMEERWIJK J; GERMAIN RN; ROBERTSON EJ
    DEFECTIVE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II ASSEMBLY, TRANSPORT, PEPTIDE ACQUISITION, AND CD4-CELL SELECTION IN MICE LACKING INVARIANT CHAIN EXPRESSION( T)
    The Journal of experimental medicine
    
    E.K. Bikoff et al., "DEFECTIVE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II ASSEMBLY, TRANSPORT, PEPTIDE ACQUISITION, AND CD4-CELL SELECTION IN MICE LACKING INVARIANT CHAIN EXPRESSION( T)", The Journal of experimental medicine, 177(6), 1993, pp. 1699-1712