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    1. Chavalitshewinkoon-Petmitr, P; Pongvilairat, G; Ralph, RK; Denny, WA; Wilairat, P
      Inhibitory effects of 9-anilinoacridines on Plasmodium falciparum gametocytes

      TROPICAL MEDICINE & INTERNATIONAL HEALTH
    2. Deady, LW; Desneves, J; Kaye, AJ; Finlay, GJ; Baguley, BC; Denny, WA
      Positioning of the carboxamide side chain in 11-oxo-11H-indeno[1,2-b]quinolinecarboxamide anticancer agents: Effects on cytotoxicity

      BIOORGANIC & MEDICINAL CHEMISTRY
    3. Mekapati, SB; Denny, WA; Kurup, A; Hansch, C
      QSAR of anticancer compounds. Bis(11-oxo-11H-indeno[1,2-b]quinoline-6-carboxamides), bis(phenazine-1-carboxamides), and bis(naphthalimides)

      BIOORGANIC & MEDICINAL CHEMISTRY
    4. Gieseg, MA; de Bock, C; Ferguson, LR; Denny, WA
      Evidence for epidermal growth factor receptor-enhanced chemosensitivity incombinations of cisplatin and the new irreversible tyrosine kinase inhibitor CI-1033

      ANTI-CANCER DRUGS
    5. Stewart, AJ; Mistry, P; Dangerfield, W; Bootle, D; Baker, M; Kofler, B; Okiji, S; Baguley, BC; Denny, WA; Charlton, PA
      Antitumor activity of XR5944, a novel and potent topoisomerase poison

      ANTI-CANCER DRUGS
    6. Denny, WA
      DNA minor groove alkylating agents

      CURRENT MEDICINAL CHEMISTRY
    7. Denny, WA
      Prodrug strategies in cancer therapy

      EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
    8. Holmes, RJ; McKeage, MJ; Murray, V; Denny, WA; McFadyen, WD
      cis-dichloroplatinum(II) complexes tethered to 9-aminoacridine-4-arboxamides: synthesis and action in resistant cell lines in vitro

      JOURNAL OF INORGANIC BIOCHEMISTRY
    9. Denny, WA
      Turning off growth signals in tumours: a new approach to cancer chemotherapy

      NEW ZEALAND MEDICAL JOURNAL
    10. Gamage, SA; Spicer, JA; Finlay, GJ; Stewart, AJ; Charlton, P; Baguley, BC; Denny, WA
      Dicationic bis(9-methylphenazine-1-carboxamides): Relationships between biological activity and linker chain structure for a series of potent topoisomerase targeted anticancer drugs

      JOURNAL OF MEDICINAL CHEMISTRY
    11. Smaill, JB; Showalter, HDH; Zhou, HR; Bridges, AJ; McNamara, DJ; Fry, DW; Nelson, JM; Sherwood, V; Vincent, PW; Roberts, BJ; Elliott, WL; Denny, WA
      Tyrosine kinase inhibitors. 18. 6-substituted 4-anilinoquinazolines and 4-anilinopyrido [3,4-d]pyrimidines as soluble, irreversible inhibitors of theepidermal growth factor receptor

      JOURNAL OF MEDICINAL CHEMISTRY
    12. Tercel, M; Lee, AE; Hogg, A; Anderson, RF; Lee, HH; Siim, BG; Denny, WA; Wilson, WR
      Hypoxia-selective antitumor agents. 16. Nitroarylmethyl quaternary salts as bioreductive prodrugs of the alkylating agent mechlorethamine

      JOURNAL OF MEDICINAL CHEMISTRY
    13. Bu, XY; Deady, LW; Finlay, GJ; Baguley, BC; Denny, WA
      Synthesis and cytotoxic activity of 7-Oxo-7H-dibenz[f,ij]isoquinoline and 7-oxo-7H-benzo[e]perimidine derivatives

      JOURNAL OF MEDICINAL CHEMISTRY
    14. Osman, S; Rowlinson-Busza, G; Luthra, SK; Aboagye, EO; Brown, GD; Brady, F; Myers, R; Gamage, SA; Denny, WA; Baguley, BC; Price, PM
      Comparative biodistribution and metabolism of carbon-11-labeled N-[2-(dimethylamino)ethyl]acridine-4-carboxamide and DNA-intercalating analogues

      CANCER RESEARCH
    15. Thompson, AM; Showalter, HDH; Denny, WA
      Synthesis of 7-substituted 3-aryl-1,6-naphthyridin-2-amines and 7-substituted 3-aryl-1,6-naphthyridin-2(1H)-ones via diazotization of 3-aryl-1,6-naphthyridine-2,7-diamines

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    16. Rewcastle, GW; Denny, WA; Showalter, HDH
      Synthesis of 4-(phenylamino)pyrimidine derivatives as ATP-competitive protein kinase inhibitors with potential for cancer chemotherapy

      CURRENT ORGANIC CHEMISTRY
    17. Ferguson, LR; Turner, PM; Denny, WA
      The mutagenic spectrum of acridine-linked aniline nitrogen mustards in AS52 cells: implications of DNA targeting with high selectivity for adenine orguanine bases

      MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
    18. Denny, WA; Wilson, WR
      Tirapazamine: a bioreductive anticancer drug that exploits tumour hypoxia

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    19. Denny, WA
      DNA minor groove alkylating agents

      EXPERT OPINION ON THERAPEUTIC PATENTS
    20. Garg, R; Denny, WA; Hansch, C
      Comparative QSAR studies on substituted bis-(acridines) and bis-(phenazines)carboxamides: A new class of anticancer agents

      BIOORGANIC & MEDICINAL CHEMISTRY
    21. Deady, LW; Desneves, J; Kaye, AJ; Finlay, GJ; Baguley, BC; Denny, WA
      Synthesis and antitumor activity of some indeno[1,2-b]quinoline-based bis carboxamides

      BIOORGANIC & MEDICINAL CHEMISTRY
    22. Chen, JJ; Deady, LW; Desneves, J; Kaye, AJ; Finlay, GJ; Baguley, BC; Denny, WA
      Synthesis of substituted indeno[1,2-b]quinoline-6-carboxamides, [1]benzothieno[3,2-b]quinoline-4-carboxamides and 10H-quindoline-4-carboxamides: Evaluation of structure-activity relationships for cytotoxicity

      BIOORGANIC & MEDICINAL CHEMISTRY
    23. Adams, A; Guss, JM; Collyer, CA; Denny, WA; Wakelin, LPG
      A novel form of intercalation involving four DNA duplexes in an acridine-4-carboxamide complex of d(CGTACG)(2)

      NUCLEIC ACIDS RESEARCH
    24. Ware, DC; Brothers, PJ; Clark, GR; Denny, WA; Palmer, BD; Wilson, WR
      Synthesis, structures and hypoxia-selective cytotoxicity of cobalt(III) complexes containing tridentate amine and nitrogen mustard ligands

      JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS
    25. Sykes, BM; Hay, MP; Bohinc-Herceg, D; Helsby, NA; O'Connor, CJ; Denny, WA
      Leaving group effects in reductively triggered fragmentation of 4-nitrobenzyl carbamates

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    26. Spicer, JA; Denny, WA
      Synthesis of tetracyclic benzodioxins as potential antitumour agents

      ANTI-CANCER DRUG DESIGN
    27. Deady, LW; Rodemann, T; Finlay, GJ; Baguley, BC; Denny, WA
      Synthesis and cytotoxic activity of carboxamide derivatives of benzimidazo[2,1-a]isoquinoline and pyrido[3 ',2 ': 4,5]imidazo[2,1-a]isoquinoline

      ANTI-CANCER DRUG DESIGN
    28. Turner, PR; Denny, WA; Ferguson, LR
      Role of DNA minor groove alkylation and DNA cross-linking in the cytotoxicity of polybenzamide mustards

      ANTI-CANCER DRUG DESIGN
    29. Perrin, LC; Prenzler, PD; Cullinane, C; Phillips, DR; Denny, WA; McFadyen, WD
      DNA targeted platinum complexes: synthesis, cytotoxicity and DNA interactions of cis-dichloroplatinum(II) complexes tethered to phenazine-1-carboxamides

      JOURNAL OF INORGANIC BIOCHEMISTRY
    30. Hay, MP; Wilson, WR; Denny, WA
      Design, synthesis and evaluation of imidazolylmethyl carbamate prodrugs ofalkylating agents

      TETRAHEDRON
    31. Adams, A; Guss, JM; Collyer, CA; Denny, WA; Prakash, AS; Wakelin, LPG
      Acridinecarboxamide topoisomerase poisons: Structural and kinetic studies of the DNA complexes of 5-substituted 9-amino-(N-(2-dimethylamino)ethyl)acridine-4-carboxamides

      MOLECULAR PHARMACOLOGY
    32. Spicer, JA; Gamage, SA; Rewcastle, GW; Finlay, GJ; Bridewell, DJA; Baguley, BC; Denny, WA
      Bis(phenazine-1-carboxamides): Structure-activity relationships for a new class of dual topoisomerase I/II-directed anticancer drugs

      JOURNAL OF MEDICINAL CHEMISTRY
    33. Smaill, JB; Rewcastle, GW; Loo, JA; Greis, KD; Chan, OH; Reyner, EL; Lipka, E; Showalter, HDH; Vincent, PW; Elliott, WL; Denny, WA
      Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions

      JOURNAL OF MEDICINAL CHEMISTRY
    34. Thompson, AM; Connolly, CJC; Hamby, JM; Boushelle, S; Hartl, BG; Amar, AM; Kraker, AJ; Driscoll, DL; Steinkampf, RW; Patmore, SJ; Vincent, PW; Roberts, BJ; Elliott, WL; Klohs, W; Leopold, WR; Showalter, HDH; Denny, WA
      3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and related 2-urea derivatives are potent and selective inhibitors of the FGF receptor-1 tyrosine kinase

      JOURNAL OF MEDICINAL CHEMISTRY
    35. Thompson, AM; Rewcastle, GW; Boushelle, SL; Hartl, BG; Kraker, AJ; Lu, GH; Batley, BL; Panek, RL; Showalter, HDH; Denny, WA
      Synthesis and structure-activity relationships of 7-substituted 3-(2,6-dichlorophenyl)-1,6-naphthyridin-2 (1H)-ones as selective inhibitors of pp60(c-src)

      JOURNAL OF MEDICINAL CHEMISTRY
    36. Smaill, JB; Rewcastle, GW; Bridges, AJ; Zhou, HR; Showalter, HDH; Fry, DW; Nelson, JM; Sherwood, V; Elliott, WL; Vincent, PW; DeJohn, DE; Loo, JA; Greis, KD; Chan, OH; Reyner, EL; Lipka, E; Denny, WA
      Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]-pyrimidine-6-acrylamides bearing additional solubilizing functions(vol 43, pg 1380, 2000)

      JOURNAL OF MEDICINAL CHEMISTRY
    37. Ferguson, LR; Liu, AP; Denny, WA; Cullinane, C; Talarico, T; Phillips, DR
      Transcriptional blockages in a cell-free system by sequence-selective DNA alkylating agents

      CHEMICO-BIOLOGICAL INTERACTIONS
    38. Thorpe, JH; Hobbs, JR; Todd, AK; Denny, WA; Charlton, P; Cardin, CJ
      Guanine specific binding at a DNA junction formed by d[CG(5-BrU)ACG]2 witha topoisomerase poison in the presence of Co2+ ions

      BIOCHEMISTRY
    39. Temple, MD; McFadyen, WD; Holmes, RJ; Denny, WA; Murray, V
      Interaction of cisplatin and DNA-targeted 9-aminoacridine platinum complexes with DNA

      BIOCHEMISTRY
    40. Siim, BG; Hicks, KO; Pullen, SM; van Zijl, PL; Denny, WA; Wilson, WR
      Comparison of aromatic and tertiary amine N-oxides of acridine DNA intercalators as bioreductive drugs - Cytotoxicity, DNA binding, cellular uptake, and metabolism

      BIOCHEMICAL PHARMACOLOGY
    41. Bu, XY; Deady, LW; Denny, WA
      Synthesis and cytotoxic activity of N-[2-(dimethylamino)ethyl] carboxamidederivatives of benzofuro[2,3-b]quinoline, 6H-quinindoline, indeno[2,1-b] quinoline and [1] benzothieno[2,3-b] quinoline

      AUSTRALIAN JOURNAL OF CHEMISTRY
    42. Deady, LW; Desneves, J; Kaye, AJ; Thompson, M; Finlay, GJ; Baguley, BC; Denny, WA
      Ring-substituted 11-oxo-11H-indeno[1,2-b]quinoline-6-carboxamides with similar patterns of cytotoxicity to the dual topo I/II inhibitor DACA

      BIOORGANIC & MEDICINAL CHEMISTRY
    43. Hay, MP; Wilson, WR; Denny, WA
      Nitrobenzyl carbamate prodrugs of enediynes for nitroreductase gene-directed enzyme prodrug therapy (GDEPT)

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    44. Hay, MP; Sykes, BM; Denny, WA; Wilson, WR
      A 2-nitroimidazole carbamate prodrug of 5-amino-1-(chloromethyl)-3-[(5,6,7-trimethoxyindol-2-yl)carbonyl]-1,2-dihydro-3H-benz[E]indole (amino-seco-CBI-TMI) for use with ADEPT and GDEPT

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    45. Tercel, M; Gieseg, MA; Milbank, JB; Boyd, M; Fan, JY; Tan, LK; Wilson, WR; Denny, WA
      Cytotoxicity and DNA Interaction of the enantiomers of 6-amino-3-(chloromethyl)-1-[(5,6,7-trimethoxyindol-2-yl)-carbonyl]indoline (amino-seco-CI-TMI)

      CHEMICAL RESEARCH IN TOXICOLOGY
    46. Fan, JY; Ohms, SJ; Boyd, M; Denny, WA
      DNA adducts of 9-anilinoacridine mustards: Characterization by NMR

      CHEMICAL RESEARCH IN TOXICOLOGY
    47. Lee, HH; Denny, WA
      A large-scale synthesis of the bioreductive drug 1,4-bis{[2-(dimethylamino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione bis-N-oxide (AQ4N)

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    48. Hay, MP; Sykes, BM; Denny, WA; O'Connor, CJ
      Substituent effects on the kinetics of reductively-initiated fragmentationof nitrobenzyl carbamates designed as triggers for bioreductive prodrugs

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    49. Lee, HH; Wilson, WR; Denny, WA
      Nitracrine N-oxides: effects of variations in the nature of the side chainN-oxide on hypoxia-selective cytotoxicity

      ANTI-CANCER DRUG DESIGN
    50. McClean, S; Costelloe, C; Denny, WA; Searcey, M; Wakelin, LPG
      Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards

      ANTI-CANCER DRUG DESIGN
    51. Perrin, LC; Wilson, WR; Denny, WA; McFadyen, WD
      The design of cobalt(III) complexes of phenazine-1-carboxamides as prointercalators and potential hypoxia-selective cytotoxins

      ANTI-CANCER DRUG DESIGN
    52. Haldane, A; Finlay, GJ; Hay, MP; Denny, WA; Baguley, BC
      Cellular uptake of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA)

      ANTI-CANCER DRUG DESIGN
    53. Spicer, JA; Gamage, SA; Atwell, GJ; Finlay, GJ; Baguley, BC; Denny, WA
      Dimeric analogues of non-cationic tricyclic aromatic carboxamides are a new class of cytotoxic agents

      ANTI-CANCER DRUG DESIGN
    54. Spicer, JA; Finlay, GJ; Baguley, BC; Velea, L; Graves, DE; Denny, WA
      5,7-disubstituted analogues of the mixed topoisomerase I/II poison N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA): DNA binding and patterns of cytotoxicity

      ANTI-CANCER DRUG DESIGN
    55. Turner, PR; Ferguson, LR; Denny, WA
      Polybenzamide mustards: structure-activity relationships for DNA sequence-specific alkylation

      ANTI-CANCER DRUG DESIGN
    56. Gieseg, MA; Matejovic, J; Denny, WA
      Comparison of the patterns of DNA alkylation by phenol and amino seco-CBI-TMI compounds: use of a PCR method for the facile preparation of single end-labelled double-stranded DNA

      ANTI-CANCER DRUG DESIGN
    57. Ainscough, EW; Brodie, AM; Denny, WA; Finlay, GJ; Gothe, SA; Ranford, JD
      Cytotoxicity of salicylaldehyde benzoylhydrazone analogs and their transition metal complexes: quantitative structure-activity relationships

      JOURNAL OF INORGANIC BIOCHEMISTRY
    58. Clark, GR; Denny, WA; Squire, CJ
      1,4-bis[4-(1-pyridinium)styryl]benzene ditosylate

      ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
    59. Tercel, M; Gieseg, MA; Denny, WA; Wilson, WR
      Synthesis and cytotoxicity of amino-seco-DSA: An amino analogue of the DNAalkylating agent duocarmycin SA

      JOURNAL OF ORGANIC CHEMISTRY
    60. Todd, AK; Adams, A; Thorpe, JH; Denny, WA; Wakelin, LPG; Cardin, CJ
      Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)(2) at 1.3-angstrom resolution

      JOURNAL OF MEDICINAL CHEMISTRY
    61. Milbank, JBJ; Tercel, M; Atwell, GJ; Wilson, WR; Hogg, A; Denny, WA
      Synthesis of 1-substituted 3-(chloromethyl)-6-aminoindoline (6-amino-seco-CI) DNA minor groove alkylating agents and structure-activity relationshipsfor their cytotoxicity

      JOURNAL OF MEDICINAL CHEMISTRY
    62. Sykes, BM; Atwell, GJ; Hogg, A; Wilson, WR; O'Connor, CJ; Denny, WA
      N-substituted 2-(2,6-dinitrophenylamino)propanamides: Novel prodrugs that release a primary amine via nitroreduction and intramolecular cyclization

      JOURNAL OF MEDICINAL CHEMISTRY
    63. Atwell, GJ; Milbank, JJB; Wilson, WR; Hogg, A; Denny, WA
      5-amino-1-(chloromethyl)-1,2 dihydro-3H-benz [e]indoles: Relationships between structure and cytotoxicity for analogues bearing different DNA minor groove binding subunits

      JOURNAL OF MEDICINAL CHEMISTRY
    64. Palmer, BD; Kraker, AJ; Hartl, BG; Panopoulos, AD; Panek, RL; Batley, BL; Lu, GH; Trumpp-Kallmeyer, S; Showalter, HDH; Denny, WA
      Structure-activity relationships for 5-substituted 1-phenylbenzimidazoles as selective inhibitors of the platelet-derived growth factor receptor

      JOURNAL OF MEDICINAL CHEMISTRY
    65. Gamage, SA; Spicer, JA; Atwell, GJ; Finlay, GJ; Baguley, BC; Denny, WA
      Structure-activity relationships for substituted bis(acridine-4-calrboxamides): A new class of anticancer agents

      JOURNAL OF MEDICINAL CHEMISTRY
    66. Smaill, JB; Palmer, BD; Rewcastle, GW; Denny, WA; McNamara, DJ; Dobrusin, EM; Bridges, AJ; Zhou, HR; Showalter, HDH; Winters, RT; Leopold, WR; Fry, DW; Nelson, JM; Slintak, V; Elliot, WL; Roberts, BJ; Vincent, PW; Patmore, SJ
      Tyrosine kinase inhibitors. 15. 4-(phenylamino)quinazoline and 4-(phenylamino)pyrido[d] pyrimidine acrylamides as irreversible inhibitors of the ATP binding site of the epidermal growth factor receptor

      JOURNAL OF MEDICINAL CHEMISTRY
    67. Lansiaux, A; Adams, A; Denny, WA; Bailly, C
      The DACA

      BULLETIN DU CANCER
    68. Adams, A; Guss, JM; Collyer, CA; Denny, WA; Wakelin, LPG
      Crystal structure of the topoisomerase II poison 9-amino-[N-(2-dimethylamino)ethyl]acridine-4-carboxamide bound to the DNA hexanucleotide d(CGTACG)(2)

      BIOCHEMISTRY
    69. Cambie, RC; Denny, WA; Hay, MP; Mitchell, LH; Rutledge, PS; Woodgate, PD
      Modifications of rings B and C of podocarpic acid: Towards the synthesis of quassinoids

      AUSTRALIAN JOURNAL OF CHEMISTRY
    70. YAGHI BM; TURNER PM; DENNY WA; TURNER PR; OCONNOR CJ; FERGUSON LR
      COMPARATIVE MUTATIONAL SPECTRA OF THE NITROGEN-MUSTARD CHLORAMBUCIL AND ITS HALF-MUSTARD ANALOG IN CHINESE-HAMSTER AS52 CELLS

      Mutation research. Fundamental and molecular mechanisms of mutagenesis
    71. FRIEDLOS F; COURT S; FORD M; DENNY WA; SPRINGER C
      GENE-DIRECTED ENZYME PRODRUG THERAPY - QUANTITATIVE BYSTANDER CYTOTOXICITY AND DNA-DAMAGE INDUCED BY CB1954 IN CELLS EXPRESSING BACTERIAL NITROREDUCTASE

      Gene therapy
    72. LEE HH; PALMER BD; WILSON WR; DENNY WA
      SYNTHESIS AND HYPOXIA-SELECTIVE CYTOTOXICITY OF A 2-NITROIMIDAZOLE MUSTARD

      Bioorganic & medicinal chemistry letters
    73. BAGULEY BC; MARSHALL ES; HOLDAWAY IM; REWCASTLE GW; DENNY WA
      INHIBITION OF GROWTH OF PRIMARY HUMAN TUMOR-CELL CULTURES BY A 4-ANILINOQUINAZOLINE INHIBITOR OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR FAMILY OF TYROSINE KINASES

      European journal of cancer
    74. PIESTRZENIEWICZ MK; WILMANSKA D; STUDZIAN K; SZEMRAJ J; CZYZ M; DENNY WA; GNIAZDOWSKI M
      INHIBITION OF RNA-SYNTHESIS IN-VITRO BY ACRIDINES - RELATION BETWEEN STRUCTURE AND ACTIVITY

      Zeitschrift fur Naturforschung. C, A journal of biosciences
    75. SMAILL JB; DENNY WA; FRY DW; NELSON JM; LEOPOLD WR; VINCENT PW; HOOK KE; ELLIOTT WL; BRIDGES AJ; ZHOU H; SHOWALTER HDH; MCNAMARA DJ; DOBRUSIN EM
      DEVELOPMENT OF IRREVERSIBLE EGFR TYROSINE KINASE INHIBITORS WITH ANTITUMOR-ACTIVITY AGAINST HUMAN TUMOR XENOGRAFTS

      Annals of oncology
    76. TERCEL M; DENNY WA
      SYNTHESIS OF NITROGEN AND SULFUR ANALOGS OF THE SECO-CI ALKYLATING AGENT

      Journal of the Chemical Society. Perkin transactions. I
    77. SMAILL JB; FAN JY; PAPA PV; OCONNOR CJ; DENNY WA
      MONOFUNCTIONAL AND DIFUNCTIONAL NITROGEN-MUSTARD ANALOGS OF THE DNA MINOR-GROOVE BINDER PIBENZIMOL - SYNTHESIS, CYTOTOXICITY AND INTERACTION WITH DNA

      Anti-cancer drug design
    78. WARE DC; PALMER HR; PRUIJN FB; ANDERSON RE; BROTHERS PJ; DENNY WA; WILSON WR
      BIS(DIALKYL)DITHIOCARBAMATO COBALT(III) COMPLEXES OF BIDENTATE NITROGEN MUSTARDS - SYNTHESIS, REDUCTION CHEMISTRY AND BIOLOGICAL EVALUATIONAS HYPOXIA-SELECTIVE CYTOTOXINS

      Anti-cancer drug design
    79. Smaill, JB; Fan, JY; Denny, WA
      DNA minor groove targeted alkylating agents based on bisbenzimidazole carriers: synthesis, cytotoxicity and sequence-specificity of DNA alkylation

      ANTI-CANCER DRUG DESIGN
    80. Turner, PR; Ferguson, LR; Denny, WA
      Binding of polybenzamides to DNA: studies by DNase I and chlorambucil interference footprinting and comparison with Hoechst 33258

      ANTI-CANCER DRUG DESIGN
    81. Wilson, WR; Tercel, M; Anderson, RF; Denny, WA
      Radiation-activated prodrugs as hypoxia-selective cytotoxins: model studies with nitroarylmethyl quaternary salts

      ANTI-CANCER DRUG DESIGN
    82. AINSCOUGH EW; BRODIE AM; DENNY WA; FINLAY GJ; RANFORD RD
      NITROGEN, SULFUR AND OXYGEN DONOR ADDUCTS WITH COPPER(II) COMPLEXES OF ANTITUMOR 2-FORMYLPYRIDINETHIOSEMICARBAZONE ANALOGS - PHYSICOCHEMICAL AND CYTOTOXIC STUDIES

      Journal of inorganic biochemistry
    83. HAY MP; DENNY WA
      AN EFFICIENT LARGE-SCALE SYNTHESIS OF 2-METHOXYTETRAHYDROPHENANTHRIDINE

      Synthetic communications
    84. WILSON WR; FERRY DM; TERCEL M; ANDERSON RF; DENNY WA
      REDUCTION OF NITROARYLMETHYL QUATERNARY AMMONIUM PRODRUGS OF MECHLORETHAMINE BY RADIATION

      Radiation research
    85. FRY DW; BRIDGES AJ; DENNY WA; DOHERTY A; GREIS KD; HICKS JL; HOOK KE; KELLER PR; LEOPOLD WR; LOO JA; MCNAMARA DJ; NELSON JM; SHERWOOD V; SMAILL JB; TRUMPPKALLMEYER S; DOBRUSIN EM
      SPECIFIC, IRREVERSIBLE INACTIVATION OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR AND ERBB2, BY A NEW CLASS OF TYROSINE KINASE INHIBITOR

      Proceedings of the National Academy of Sciences of the United Statesof America
    86. Denny, WA; Wilson, WR
      The design of selectively-activated anti-cancer prodrugs for use in antibody-directed and gene-directed enzyme-prodrug therapies

      JOURNAL OF PHARMACY AND PHARMACOLOGY
    87. Atwell, GJ; Tercel, M; Boyd, M; Wilson, WR; Denny, WA
      Synthesis and cytotoxicity of 5-amino-1-(chloromethyl)-3-[(5,6,7-trimethoxyindol-2-yl)carbonyl]-1,2-dihydro-3H-benz[e]indole (amino-seco-CBI-TMI) andrelated 5-alkylamino analogues: New DNA minor groove alkylating agents

      JOURNAL OF ORGANIC CHEMISTRY
    88. REWCASTLE GW; MURRAY DK; ELLIOTT WL; FRY DW; HOWARD CT; NELSON JM; ROBERTS BJ; VINCENT PW; SHOWALTER HDH; WINTERS RT; DENNY WA
      TYROSINE KINASE INHIBITORS - 14 - STRUCTURE-ACTIVITY-RELATIONSHIPS FOR METHYLAMINO-SUBSTITUTED DERIVATIVES OF ENYL)AMINO]-6-(METHYLAMINO)PYRIDO[3,4-D]PYRIMIDINE (PD-158780), A POTENT AND SPECIFIC INHIBITOR OF THE TYROSINE KINASE-ACTIVITY OF RECEPTORS FOR THE EGF FAMILY OF GROWTH-FACTORS

      Journal of medicinal chemistry
    89. ATWELL GJ; FAN JY; TAN K; DENNY WA
      DNA-DIRECTED ALKYLATING-AGENTS - 7 - SYNTHESIS, DNA INTERACTION, AND ANTITUMOR-ACTIVITY OF BIS(HYDROXYMETHYL)-SUBSTITUTED AND BIS(CARBAMATE)-SUBSTITUTED PYRROLIZINES AND IMIDAZOLES

      Journal of medicinal chemistry
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ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/10/20 alle ore 01:46:47