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1. Barnes, PJ
   Th2 cytokines and asthma: an introduction
   RESPIRATORY RESEARCH
   
   P.J. Barnes, "Th2 cytokines and asthma: an introduction", RESPIR RES, 2(2), 2001, pp. 64-65
2. Barnes, PJ; Hansel, TT
   The need for new therapy
   NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
   
   P.J. Barnes e T.T. Hansel, "The need for new therapy", PROG R RES, 31, 2001, pp. 2-5
3. Barnes, PJ
   Current therapy for asthma
   NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
   
   P.J. Barnes, "Current therapy for asthma", PROG R RES, 31, 2001, pp. 6-10
4. Kharitonov, SA; Barnes, PJ
   Exhaled breath analysis
   NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
   
   S.A. Kharitonov e P.J. Barnes, "Exhaled breath analysis", PROG R RES, 31, 2001, pp. 44-47
5. Hansel, TT; Barnes, PJ
   Clinical studies on new drugs
   NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
   
   T.T. Hansel e P.J. Barnes, "Clinical studies on new drugs", PROG R RES, 31, 2001, pp. 48-51
6. Barnes, PJ
   Tiotropium bromide
   EXPERT OPINION ON INVESTIGATIONAL DRUGS
   
   P.J. Barnes, "Tiotropium bromide", EXPERT OP I, 10(4), 2001, pp. 733-740
7. O'Byrne, PM; Barnes, PJ; Rodriguez-Roisin, R; Runnerstrom, E; Sandstrom, T; Svensson, K; Tattersfield, A
   Low dose inhaled budesonide and formoterol in mild persistent asthma - TheOPTIMA randomized trial
   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
   
   P.M. O'Byrne et al., "Low dose inhaled budesonide and formoterol in mild persistent asthma - TheOPTIMA randomized trial", AM J R CRIT, 164(8), 2001, pp. 1392-1397
8. Stirling, RG; Van Rensen, ELJ; Barnes, PJ; Chung, KF
   Interleukin-5 induces CD34(+) eosinophil progenitor mobilization and eosinophil CCR3 expression in asthma
   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
   
   R.G. Stirling et al., "Interleukin-5 induces CD34(+) eosinophil progenitor mobilization and eosinophil CCR3 expression in asthma", AM J R CRIT, 164(8), 2001, pp. 1403-1409
9. Kharitonov, SA; Barnes, PJ
   Does exhaled nitric oxide reflect asthma control? Yes, it does!
   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
   
   S.A. Kharitonov e P.J. Barnes, "Does exhaled nitric oxide reflect asthma control? Yes, it does!", AM J R CRIT, 164(5), 2001, pp. 727-728
10. Lim, S; Tomita, K; Carramori, G; Jatakanon, A; Oliver, B; Keller, A; Adcock, I; Chung, KF; Barnes, PJ
    Low-dose theophylline reduces eosinophilic inflammation but not exhaled nitric oxide in mild asthma
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    S. Lim et al., "Low-dose theophylline reduces eosinophilic inflammation but not exhaled nitric oxide in mild asthma", AM J R CRIT, 164(2), 2001, pp. 273-276
11. Kharitonov, SA; Barnes, PJ
    Exhaled markers of pulmonary disease
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    S.A. Kharitonov e P.J. Barnes, "Exhaled markers of pulmonary disease", AM J R CRIT, 163(7), 2001, pp. 1693-1722
12. Corradi, M; Montuschi, P; Donnelly, LE; Pesci, A; Kharitonov, SA; Barnes, PJ
    Increased nitrosothiols in exhaled breath condensate in inflammatory airway diseases
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    M. Corradi et al., "Increased nitrosothiols in exhaled breath condensate in inflammatory airway diseases", AM J R CRIT, 163(4), 2001, pp. 854-858
13. Pype, JL; Xu, HY; Schuermans, M; Dupont, LJ; Wuyts, W; Mak, JCW; Barnes, PJ; Demedts, MG; Verleden, GM
    Mechanisms of interleukin 1 beta-induced human airway smooth muscle hyporesponsiveness to histamine - Involvement of p38 MAPK and NF-kappa B
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    J.L. Pype et al., "Mechanisms of interleukin 1 beta-induced human airway smooth muscle hyporesponsiveness to histamine - Involvement of p38 MAPK and NF-kappa B", AM J R CRIT, 163(4), 2001, pp. 1010-1017
14. Donnelly, LE; Barnes, PJ
    Expression of heme oxygenase in human airway epithelial cells
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
    
    L.E. Donnelly e P.J. Barnes, "Expression of heme oxygenase in human airway epithelial cells", AM J RESP C, 24(3), 2001, pp. 295-303
15. Di Stefano, A; Capelli, A; Lusuardi, M; Caramori, G; Balbo, P; Ioli, F; Sacco, S; Gnemmi, I; Brun, P; Adcock, IM; Balbi, B; Barnes, PJ; Chung, KF; Donner, CF
    Decreased T lymphocyte infiltration in bronchial biopsies of subjects withsevere chronic obstructive pulmonary disease
    CLINICAL AND EXPERIMENTAL ALLERGY
    
    A. Di Stefano et al., "Decreased T lymphocyte infiltration in bronchial biopsies of subjects withsevere chronic obstructive pulmonary disease", CLIN EXP AL, 31(6), 2001, pp. 893-902
16. Barnes, PJ
    IL-10: a key regulator of allergic disease
    CLINICAL AND EXPERIMENTAL ALLERGY
    
    P.J. Barnes, "IL-10: a key regulator of allergic disease", CLIN EXP AL, 31(5), 2001, pp. 667-669
17. Andersson, F; Stahl, E; Barnes, PJ; Lofdahl, CG; O'Byrne, PM; Pauwels, RA; Postma, DS; Tattersfield, AE; Ullman, A
    Adding formoterol to budesonide in moderate asthma - health economic results from the FACET study
    RESPIRATORY MEDICINE
    
    F. Andersson et al., "Adding formoterol to budesonide in moderate asthma - health economic results from the FACET study", RESP MED, 95(6), 2001, pp. 505-512
18. Barnes, PJ
    Clinical outcome of adding long-acting beta-agonists to inhaled corticosteroids
    RESPIRATORY MEDICINE
    
    P.J. Barnes, "Clinical outcome of adding long-acting beta-agonists to inhaled corticosteroids", RESP MED, 95, 2001, pp. S12-S16
19. Caramori, G; Lim, S; Ito, K; Tomita, K; Oates, T; Jazrawi, E; Chung, KF; Barnes, PJ; Adcock, IM
    Expression of GATA family of transcription factors in T-cells, monocytes and bronchial biopsies
    EUROPEAN RESPIRATORY JOURNAL
    
    G. Caramori et al., "Expression of GATA family of transcription factors in T-cells, monocytes and bronchial biopsies", EUR RESP J, 18(3), 2001, pp. 466-473
20. Balint, B; Kharitonov, SA; Hanazawa, T; Donnelly, LE; Shah, PL; Hodson, ME; Barnes, PJ
    Increased nitrotyrosine in exhaled breath condensate in cystic fibrosis
    EUROPEAN RESPIRATORY JOURNAL
    
    B. Balint et al., "Increased nitrotyrosine in exhaled breath condensate in cystic fibrosis", EUR RESP J, 17(6), 2001, pp. 1201-1207
21. Fujita, K; Kasayama, S; Hashimoto, J; Nagasaka, Y; Nakano, N; Morimoto, Y; Barnes, PJ; Miyatake, A
    Inhaled corticosteroids reduce bone mineral density in early postmenopausal but not premenopausal asthmatic women
    JOURNAL OF BONE AND MINERAL RESEARCH
    
    K. Fujita et al., "Inhaled corticosteroids reduce bone mineral density in early postmenopausal but not premenopausal asthmatic women", J BONE MIN, 16(4), 2001, pp. 782-787
22. Robinson, D; Campbell, DA; Barnes, PJ
    Montelukast for persistent asthma - Reply
    LANCET
    
    D. Robinson et al., "Montelukast for persistent asthma - Reply", LANCET, 358(9291), 2001, pp. 1455-1456
23. Robinson, DS; Campbell, D; Barnes, PJ
    Addition of leukotriene antagonists to therapy in chronic persistent asthma: a randomised double-blind placebo-controlled trial
    LANCET
    
    D.S. Robinson et al., "Addition of leukotriene antagonists to therapy in chronic persistent asthma: a randomised double-blind placebo-controlled trial", LANCET, 357(9273), 2001, pp. 2007-2011
24. Hansel, TT; Barnes, PJ
    Eosinophils and airway hyper-responsiveness - Reply
    LANCET
    
    T.T. Hansel e P.J. Barnes, "Eosinophils and airway hyper-responsiveness - Reply", LANCET, 357(9266), 2001, pp. 1446-1446
25. Oliver, B; Tomita, K; Keller, A; Caramori, G; Adcock, I; Chung, KF; Barnes, PJ; Lim, S
    Low-dose theophylline does not exert its anti-inflammatory effects in mildasthma through upregulation of interleukin-10 in alveolar macrophages
    ALLERGY
    
    B. Oliver et al., "Low-dose theophylline does not exert its anti-inflammatory effects in mildasthma through upregulation of interleukin-10 in alveolar macrophages", ALLERGY, 56(11), 2001, pp. 1087-1090
26. Barnes, PJ
    Allergy review series VII: Intracellular signaling and regulation of allergic reactions - Molecular mechanisms of corticosteroids in allergic diseases
    ALLERGY
    
    P.J. Barnes, "Allergy review series VII: Intracellular signaling and regulation of allergic reactions - Molecular mechanisms of corticosteroids in allergic diseases", ALLERGY, 56(10), 2001, pp. 928-936
27. Barnes, PJ
    Cytokine-directed therapies for asthma
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    
    P.J. Barnes, "Cytokine-directed therapies for asthma", J ALLERG CL, 108(2), 2001, pp. S72-S76
28. Balint, B; Donnelly, LE; Hanazawa, T; Kharitonov, SA; Barnes, PJ
    Increased nitric oxide metabolites in exhaled breath condensate after exposure to tobacco smoke
    THORAX
    
    B. Balint et al., "Increased nitric oxide metabolites in exhaled breath condensate after exposure to tobacco smoke", THORAX, 56(6), 2001, pp. 456-461
29. van Rensen, ELJ; Stirling, RG; Scheerens, J; Staples, K; Sterk, PJ; Barnes, PJ; Chung, KF
    Evidence for systemic rather than pulmonary effects of interleukin-5 administration in asthma
    THORAX
    
    E.L.J. van Rensen et al., "Evidence for systemic rather than pulmonary effects of interleukin-5 administration in asthma", THORAX, 56(12), 2001, pp. 935-940
30. Barnes, PJ
    Neurogenic inflammation in the airways
    RESPIRATION PHYSIOLOGY
    
    P.J. Barnes, "Neurogenic inflammation in the airways", RESP PHYSL, 125(1-2), 2001, pp. 145-154
31. Barnes, PJ
    Future advances in COPD therapy
    RESPIRATION
    
    P.J. Barnes, "Future advances in COPD therapy", RESPIRATION, 68(5), 2001, pp. 441-448
32. Paredi, P; Kharitonov, SA; Hanazawa, T; Barnes, PJ
    Local vasodilator response to mobile phones
    LARYNGOSCOPE
    
    P. Paredi et al., "Local vasodilator response to mobile phones", LARYNGOSCOP, 111(1), 2001, pp. 159-162
33. Staples, KJ; Bergmann, M; Tomita, K; Houslay, MD; McPhee, I; Barnes, PJ; Giembycz, MA; Newton, R
    Adenosine 3 ',5 '-cyclic monophosphate (cAMP)-dependent inhibition of IL-5from human T lymphocytes is not mediated by the cAMP-dependent protein kinase A(1)
    JOURNAL OF IMMUNOLOGY
    
    K.J. Staples et al., "Adenosine 3 ',5 '-cyclic monophosphate (cAMP)-dependent inhibition of IL-5from human T lymphocytes is not mediated by the cAMP-dependent protein kinase A(1)", J IMMUNOL, 167(4), 2001, pp. 2074-2080
34. Barnes, PJ
    Corticosteroids, IgE, and atopy
    JOURNAL OF CLINICAL INVESTIGATION
    
    P.J. Barnes, "Corticosteroids, IgE, and atopy", J CLIN INV, 107(3), 2001, pp. 265-266
35. Ito, K; Jazrawi, E; Cosio, BJ; Barnes, PJ; Adcock, IM
    p65-activated histone acetyltransferase activity is repressed by glucocorticoids
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    K. Ito et al., "p65-activated histone acetyltransferase activity is repressed by glucocorticoids", J BIOL CHEM, 276(32), 2001, pp. 30208-30215
36. Kagoshima, M; Wilcke, T; Ito, K; Tsaprouni, L; Barnes, PJ; Punchard, N; Adcock, IM
    Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation
    EUROPEAN JOURNAL OF PHARMACOLOGY
    
    M. Kagoshima et al., "Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation", EUR J PHARM, 429(1-3), 2001, pp. 327-334
37. Fox, AJ; Patel, HJ; Barnes, PJ; Belvisi, MG
    Release of nerve growth factor by human pulmonary epithelial cells: role in airway inflammatory diseases
    EUROPEAN JOURNAL OF PHARMACOLOGY
    
    A.J. Fox et al., "Release of nerve growth factor by human pulmonary epithelial cells: role in airway inflammatory diseases", EUR J PHARM, 424(2), 2001, pp. 159-162
38. Spicuzza, L; Barnes, PJ; Di Maria, GU; Belvisi, MG
    Effect of 8-iso-prostaglandin F-2 alpha on acetylcholine release from parasympathetic nerves in guinea pig airways
    EUROPEAN JOURNAL OF PHARMACOLOGY
    
    L. Spicuzza et al., "Effect of 8-iso-prostaglandin F-2 alpha on acetylcholine release from parasympathetic nerves in guinea pig airways", EUR J PHARM, 416(3), 2001, pp. 231-234
39. Emelyanov, A; Fedoseev, G; Abulimity, A; Rudinski, K; Fedoulov, A; Karabanov, A; Barnes, PJ
    Elevated concentrations of exhaled hydrogen peroxide in asthmatic patients
    CHEST
    
    A. Emelyanov et al., "Elevated concentrations of exhaled hydrogen peroxide in asthmatic patients", CHEST, 120(4), 2001, pp. 1136-1139
40. Montuschi, P; Kharitonov, SA; Barnes, PJ
    Exhaled carbon monoxide and nitric oxide in COPD
    CHEST
    
    P. Montuschi et al., "Exhaled carbon monoxide and nitric oxide in COPD", CHEST, 120(2), 2001, pp. 496-501
41. Lynch, OT; Giembycz, MA; Barnes, PJ; Lindsay, MA
    Pharmacological comparison of LTB4-induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils
    BRITISH JOURNAL OF PHARMACOLOGY
    
    O.T. Lynch et al., "Pharmacological comparison of LTB4-induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils", BR J PHARM, 134(4), 2001, pp. 797-806
42. Spicuzza, L; Belvisi, MG; Birrell, MA; Barnes, PJ; Hele, DJ; Giembycz, MA
    Evidence that the anti-spasmogenic effect of the beta-adrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase
    BRITISH JOURNAL OF PHARMACOLOGY
    
    L. Spicuzza et al., "Evidence that the anti-spasmogenic effect of the beta-adrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase", BR J PHARM, 133(8), 2001, pp. 1201-1212
43. Finney, PA; Donnelly, LE; Belvisi, MG; Chuang, TT; Birrell, M; Harris, A; Mak, JCW; Scorer, C; Barnes, PJ; Adcock, IM; Giembycz, MA
    Chronic systemic administration of salmeterol to rats promotes pulmonary beta(2)-adrenoceptor desensitization and down-regulation of G(s alpha)
    BRITISH JOURNAL OF PHARMACOLOGY
    
    P.A. Finney et al., "Chronic systemic administration of salmeterol to rats promotes pulmonary beta(2)-adrenoceptor desensitization and down-regulation of G(s alpha)", BR J PHARM, 132(6), 2001, pp. 1261-1270
44. Newton, R; Staples, KJ; Hart, L; Barnes, PJ; Bergmann, MW
    GM-CSF expression in pulmonary epithelial cells is regulated negatively byposttranscriptional mechanisms
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    
    R. Newton et al., "GM-CSF expression in pulmonary epithelial cells is regulated negatively byposttranscriptional mechanisms", BIOC BIOP R, 287(1), 2001, pp. 249-253
45. Paredi, P; Kharitonov, SA; Barnes, PJ
    Measurement of exhaled hydrocarbons
    HUMAN AIRWAY INFLAMMATION
    
    P. Paredi et al., "Measurement of exhaled hydrocarbons", METH MOL M, 56, 2001, pp. 109-118
46. Bryan, SA; Leckie, MJ; Jenkins, G; Barnes, PJ; Williams, TJ; Sabroe, I; Hansel, TT
    Measurement of granulocyte pharmacodynamics in whole blood by flow cytometry
    HUMAN AIRWAY INFLAMMATION
    
    S.A. Bryan et al., "Measurement of granulocyte pharmacodynamics in whole blood by flow cytometry", METH MOL M, 56, 2001, pp. 345-355
47. Barnes, PJ
    Gene regulation of muscarinic receptor subtypes
    MUSCARINIC RECEPTORS IN AIRWAYS DISEASES
    
    P.J. Barnes, "Gene regulation of muscarinic receptor subtypes", PROG INFLAM, 2001, pp. 159-173
48. Leckie, MJ; Bryan, SA; Hansel, TT; Barnes, PJ
    Novel therapy for COPD
    EXPERT OPINION ON INVESTIGATIONAL DRUGS
    
    M.J. Leckie et al., "Novel therapy for COPD", EXPERT OP I, 9(1), 2000, pp. 3-23
49. Bryan, SA; Leckie, MJ; Hansel, TT; Barnes, PJ
    Novel therapy for asthma
    EXPERT OPINION ON INVESTIGATIONAL DRUGS
    
    S.A. Bryan et al., "Novel therapy for asthma", EXPERT OP I, 9(1), 2000, pp. 25-42
50. Lim, S; Groneberg, D; Fischer, A; Oates, T; Caramori, G; Mattos, W; Adcock, I; Barnes, PJ; Chung, KF
    Expression of heme oxygenase isoenzymes 1 and 2 in normal and asthmatic airways - Effect of inhaled corticosteroids
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    S. Lim et al., "Expression of heme oxygenase isoenzymes 1 and 2 in normal and asthmatic airways - Effect of inhaled corticosteroids", AM J R CRIT, 162(5), 2000, pp. 1912-1918
51. Hanazawa, T; Kharitonov, SA; Barnes, PJ
    Increased nitrotyrosine in exhaled breath condensate of patients with asthma
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    T. Hanazawa et al., "Increased nitrotyrosine in exhaled breath condensate of patients with asthma", AM J R CRIT, 162(4), 2000, pp. 1273-1276
52. Lim, S; Roche, N; Oliver, BG; Mattos, W; Barnes, PJ; Chung, KF
    Balance of matrix metalloprotease-9 and tissue inhibitor of metalloprotease-1 from alveolar macrophages in cigarette smokers - Regulation by interleukin-10
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    S. Lim et al., "Balance of matrix metalloprotease-9 and tissue inhibitor of metalloprotease-1 from alveolar macrophages in cigarette smokers - Regulation by interleukin-10", AM J R CRIT, 162(4), 2000, pp. 1355-1360
53. Paredi, P; Kharitonov, SA; Barnes, PJ
    Elevation of exhaled ethane concentration in asthma
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    P. Paredi et al., "Elevation of exhaled ethane concentration in asthma", AM J R CRIT, 162(4), 2000, pp. 1450-1454
54. Montuschi, P; Collins, JV; Ciabattoni, G; Lazzeri, N; Corradi, M; Kharitonov, SA; Barnes, PJ
    Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    P. Montuschi et al., "Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers", AM J R CRIT, 162(3), 2000, pp. 1175-1177
55. Paredi, P; Kharitonov, SA; Leak, D; Ward, S; Cramer, D; Barnes, PJ
    Exhaled ethane, a marker of lipid peroxidation, is elevated in chronic obstructive pulmonary disease
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    P. Paredi et al., "Exhaled ethane, a marker of lipid peroxidation, is elevated in chronic obstructive pulmonary disease", AM J R CRIT, 162(2), 2000, pp. 369-373
56. Nightingale, JA; Maggs, R; Cullinan, P; Donnelly, LE; Rogers, DF; Kinnersley, R; Chung, KF; Barnes, PJ; Ashmore, M; Newman-Taylor, A
    Airway inflammation after controlled exposure to diesel exhaust particulates
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    J.A. Nightingale et al., "Airway inflammation after controlled exposure to diesel exhaust particulates", AM J R CRIT, 162(1), 2000, pp. 161-166
57. Paredi, P; Kharitonov, SA; Leak, D; Shah, PL; Cramer, D; Hodson, ME; Barnes, PJ
    Exhaled ethane is elevated in cystic fibrosis and correlates with carbon monoxide levels and airway obstruction
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    P. Paredi et al., "Exhaled ethane is elevated in cystic fibrosis and correlates with carbon monoxide levels and airway obstruction", AM J R CRIT, 161(4), 2000, pp. 1247-1251
58. Woolcock, AJ; Barnes, PJ
    Asthma: The important questions Part 4 - Introduction
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    A.J. Woolcock e P.J. Barnes, "Asthma: The important questions Part 4 - Introduction", AM J R CRIT, 161(3), 2000, pp. S157-S157
59. Barnes, PJ
    Endogenous inhibitory mechanisms in asthma
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    P.J. Barnes, "Endogenous inhibitory mechanisms in asthma", AM J R CRIT, 161(3), 2000, pp. S176-S181
60. Barnes, PJ
    Inhaled corticosteroids are not beneficial in chronic obstructive pulmonary disease
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    P.J. Barnes, "Inhaled corticosteroids are not beneficial in chronic obstructive pulmonary disease", AM J R CRIT, 161(2), 2000, pp. 342-344
61. Barnes, PJ
    Inhaled corticosteroids are not beneficial in chronic obstructive pulmonary disease - Rebuttal from Dr. Barnes
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    P.J. Barnes, "Inhaled corticosteroids are not beneficial in chronic obstructive pulmonary disease - Rebuttal from Dr. Barnes", AM J R CRIT, 161(2), 2000, pp. 344-344
62. Nightingale, JA; Rogers, DF; Chung, KF; Barnes, PJ
    No effect of inhaled budesonide on the response to inhaled ozone in normalsubjects
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    J.A. Nightingale et al., "No effect of inhaled budesonide on the response to inhaled ozone in normalsubjects", AM J R CRIT, 161(2), 2000, pp. 479-486
63. Taha, R; Olivenstein, R; Utsumi, T; Ernst, P; Barnes, PJ; Rodger, IW; Giaid, A
    Prostaglandin H synthase 2 expression in airway cells from patients with asthma and chronic obstructive pulmonary disease
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    R. Taha et al., "Prostaglandin H synthase 2 expression in airway cells from patients with asthma and chronic obstructive pulmonary disease", AM J R CRIT, 161(2), 2000, pp. 636-640
64. Jatakanon, A; Lim, S; Barnes, PJ
    Changes in sputum eosinophils predict less of asthma control
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    A. Jatakanon et al., "Changes in sputum eosinophils predict less of asthma control", AM J R CRIT, 161(1), 2000, pp. 64-72
65. Hart, L; Lim, S; Adcock, I; Barnes, PJ; Chung, KF
    Effects of inhaled corticosteroid therapy on expression and DNA-binding activity of nuclear factor kappa B in asthma
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    
    L. Hart et al., "Effects of inhaled corticosteroid therapy on expression and DNA-binding activity of nuclear factor kappa B in asthma", AM J R CRIT, 161(1), 2000, pp. 224-231
66. Bergmann, M; Barnes, PJ; Newton, R
    Molecular regulation of granulocyte macrophage colony-stimulating factor in human lung epithelial cells by interleukin (IL)-1 beta, IL-4, and IL-13 involves both transcriptional and post-transcriptional mechanisms
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
    
    M. Bergmann et al., "Molecular regulation of granulocyte macrophage colony-stimulating factor in human lung epithelial cells by interleukin (IL)-1 beta, IL-4, and IL-13 involves both transcriptional and post-transcriptional mechanisms", AM J RESP C, 22(5), 2000, pp. 582-589
67. Barnes, PJ
    Anti-IgE therapy in asthma: Rationale and therapeutic potential
    INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
    
    P.J. Barnes, "Anti-IgE therapy in asthma: Rationale and therapeutic potential", INT A AL IM, 123(3), 2000, pp. 196-204
68. Barnes, PJ
    Molecular basis for corticosteroid action in asthma
    IMMUNOLOGICAL MECHANISMS IN ASTHMA AND ALLERGIC DISEASES
    
    P.J. Barnes, "Molecular basis for corticosteroid action in asthma", CHEM IMMUNO, 78, 2000, pp. 72-80
69. Kharitonov, SA; Barnes, PJ
    Clinical aspects of exhaled nitric oxide
    EUROPEAN RESPIRATORY JOURNAL
    
    S.A. Kharitonov e P.J. Barnes, "Clinical aspects of exhaled nitric oxide", EUR RESP J, 16(4), 2000, pp. 781-792
70. Ranu, HK; Mak, JCW; Barnes, PJ; Harding, SE
    G(i)-dependent suppression of beta(1)-adrenoceptor effects in ventricular myocytes from NE-treated guinea pigs
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    
    H.K. Ranu et al., "G(i)-dependent suppression of beta(1)-adrenoceptor effects in ventricular myocytes from NE-treated guinea pigs", AM J P-HEAR, 278(6), 2000, pp. H1807-H1814
71. Ito, K; Barnes, PJ; Adcock, IM
    Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1 beta-induced histone H4 acetylation on lysines 8 and 12
    MOLECULAR AND CELLULAR BIOLOGY
    
    K. Ito et al., "Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1 beta-induced histone H4 acetylation on lysines 8 and 12", MOL CELL B, 20(18), 2000, pp. 6891-6903
72. Leckie, MJ; ten Brinke, A; Khan, J; Diamant, Z; O'Connor, BJ; Walls, CM; Mathur, AK; Cowley, HC; Chung, KF; Djukanovic, R; Hansel, TT; Holgate, T; Sterk, PJ; Barnes, PJ
    Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
    LANCET
    
    M.J. Leckie et al., "Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response", LANCET, 356(9248), 2000, pp. 2144-2148
73. Bryan, SA; O'Connor, BJ; Matti, S; Leckie, MJ; Kanabar, V; Khan, J; Warrington, SJ; Renzetti, L; Rames, A; Bock, JA; Boyce, MJ; Hansel, TT; Holgate, ST; Barnes, PJ
    Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response
    LANCET
    
    S.A. Bryan et al., "Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response", LANCET, 356(9248), 2000, pp. 2149-2153
74. Dennis, SM; Sharp, SJ; Vickers, MR; Frost, CD; Crompton, GK; Barnes, PJ; Lee, TH
    Regular inhaled salbutamol and asthma control: the TRUST randomised trial
    LANCET
    
    S.M. Dennis et al., "Regular inhaled salbutamol and asthma control: the TRUST randomised trial", LANCET, 355(9216), 2000, pp. 1675-1679
75. Lim, S; John, M; Seybold, J; Taylor, D; Witt, C; Barnes, PJ; Chung, KF
    Increased interleukin-10 and macrophage inflammatory protein-1 alpha release from blood monocytes ex vivo during late-phase response to allergen in asthma
    ALLERGY
    
    S. Lim et al., "Increased interleukin-10 and macrophage inflammatory protein-1 alpha release from blood monocytes ex vivo during late-phase response to allergen in asthma", ALLERGY, 55(5), 2000, pp. 489-495
76. Katsunuma, T; Fujita, K; Mak, JCW; Barnes, PJ; Ueno, K; Iikura, Y
    beta-Adrenergic agonists and bronchial hyperreactivity: Role of beta(2)-adrenergic and tachykinin neurokinin-2 receptors
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    
    T. Katsunuma et al., "beta-Adrenergic agonists and bronchial hyperreactivity: Role of beta(2)-adrenergic and tachykinin neurokinin-2 receptors", J ALLERG CL, 106(1), 2000, pp. S104-S108
77. Barnes, PJ
    New directions in allergic diseases: Mechanism-based anti-inflammatory therapies
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    
    P.J. Barnes, "New directions in allergic diseases: Mechanism-based anti-inflammatory therapies", J ALLERG CL, 106(1), 2000, pp. 5-16
78. Kankaanranta, H; Lindsay, MA; Giembycz, MA; Zhang, XZ; Moilanen, E; Barnes, PJ
    Delayed eosinophil apoptosis in asthma
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    
    H. Kankaanranta et al., "Delayed eosinophil apoptosis in asthma", J ALLERG CL, 106(1), 2000, pp. 77-83
79. Hanazawa, T; Antuni, JD; Kharitonov, SA; Barnes, PJ
    Intranasal administration of eotaxin increases nasal eosinophils and nitric oxide in patients with allergic rhinitis
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    
    T. Hanazawa et al., "Intranasal administration of eotaxin increases nasal eosinophils and nitric oxide in patients with allergic rhinitis", J ALLERG CL, 105(1), 2000, pp. 58-64
80. Byrnes, C; Shrewsbury, S; Barnes, PJ; Bush, A
    Salmeterol in paediatric asthma
    THORAX
    
    C. Byrnes et al., "Salmeterol in paediatric asthma", THORAX, 55(9), 2000, pp. 780-784
81. Leckie, MJ; Bryan, SA; Khan, J; Dewar, A; Aikman, SL; McGrath, J; Okrongly, DA; Burman, JF; Barnes, PJ; Hansel, TT
    Automated quantitation of circulating neutrophil and eosinophil activationin asthmatic patients
    THORAX
    
    M.J. Leckie et al., "Automated quantitation of circulating neutrophil and eosinophil activationin asthmatic patients", THORAX, 55(6), 2000, pp. 471-477
82. Lim, S; Jatakanon, A; Meah, S; Oates, T; Chung, KF; Barnes, PJ
    Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in mild to moderately severe asthma
    THORAX
    
    S. Lim et al., "Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in mild to moderately severe asthma", THORAX, 55(3), 2000, pp. 184-188
83. Montuschi, P; Kharitonov, SA; Ciabattoni, G; Corradi, M; van Rensen, L; Geddes, DM; Hodson, ME; Barnes, PJ
    Exhaled 8-isoprostane as a new non-invasive biomarker of oxidative stress in cystic fibrosis
    THORAX
    
    P. Montuschi et al., "Exhaled 8-isoprostane as a new non-invasive biomarker of oxidative stress in cystic fibrosis", THORAX, 55(3), 2000, pp. 205-209
84. Antuni, JD; Kharitonov, SA; Hughes, D; Hodson, ME; Barnes, PJ
    Increase in exhaled carbon monoxide during exacerbations of cystic fibrosis
    THORAX
    
    J.D. Antuni et al., "Increase in exhaled carbon monoxide during exacerbations of cystic fibrosis", THORAX, 55(2), 2000, pp. 138-142
85. Lim, S; Jatakanon, A; Gordon, D; Macdonald, C; Chung, KF; Barnes, PJ
    Comparison of high dose inhaled steroids, low dose inhaled steroids plus low dose theophylline, and low dose inhaled steroids alone in chronic asthmain general practice
    THORAX
    
    S. Lim et al., "Comparison of high dose inhaled steroids, low dose inhaled steroids plus low dose theophylline, and low dose inhaled steroids alone in chronic asthmain general practice", THORAX, 55(10), 2000, pp. 837-841
86. Barnes, PJ
    Medical progress: Chronic obstructive pulmonary disease.
    NEW ENGLAND JOURNAL OF MEDICINE
    
    P.J. Barnes, "Medical progress: Chronic obstructive pulmonary disease.", N ENG J MED, 343(4), 2000, pp. 269-280
87. Barnes, PJ
    Chronic obstructive pulmonary disease. Reply
    NEW ENGLAND JOURNAL OF MEDICINE
    
    P.J. Barnes, "Chronic obstructive pulmonary disease. Reply", N ENG J MED, 343(26), 2000, pp. 1970-1971
88. Mak, JCW; Rousell, J; Haddad, E; Barnes, PJ
    Transforming growth factor-beta(1) inhibits beta(2)-adrenoceptor gene transcription
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    
    J.C.W. Mak et al., "Transforming growth factor-beta(1) inhibits beta(2)-adrenoceptor gene transcription", N-S ARCH PH, 362(6), 2000, pp. 520-525
89. Haddad, EB; Fox, AJ; Rousell, J; Burgess, G; McIntyre, P; Barnes, PJ; Chung, KF
    Post-transcriptional regulation of bradykinin b1 and b2 receptor gene expression in human lung fibroblasts by tumor necrosis factor-alpha: Modulationby dexamethasone
    MOLECULAR PHARMACOLOGY
    
    E.B. Haddad et al., "Post-transcriptional regulation of bradykinin b1 and b2 receptor gene expression in human lung fibroblasts by tumor necrosis factor-alpha: Modulationby dexamethasone", MOLEC PHARM, 57(6), 2000, pp. 1123-1131
90. Mak, JCW; Roffel, AF; Katsunuma, T; Elzinga, CRS; Zaagsma, J; Barnes, PJ
    Up-regulation of airway smooth muscle histamine H-1 receptor mRNA, protein, and function by beta(2)-adrenoceptor activation
    MOLECULAR PHARMACOLOGY
    
    J.C.W. Mak et al., "Up-regulation of airway smooth muscle histamine H-1 receptor mRNA, protein, and function by beta(2)-adrenoceptor activation", MOLEC PHARM, 57(5), 2000, pp. 857-864
91. Kharitonov, SA; Barnes, PJ
    Exhaled carbon monoxide in asthma - Reply
    JOURNAL OF PEDIATRICS
    
    S.A. Kharitonov e P.J. Barnes, "Exhaled carbon monoxide in asthma - Reply", J PEDIAT, 137(6), 2000, pp. 890-891
92. Finney, PA; Belvisi, MG; Donnelly, LE; Chuang, TT; Mak, JCW; Scorer, C; Barnes, PJ; Adcock, IM; Giembycz, MA
    Albuterol-induced downregulation of Gs alpha accounts for pulmonary beta(2)-adrenoceptor desensitization in vivo
    JOURNAL OF CLINICAL INVESTIGATION
    
    P.A. Finney et al., "Albuterol-induced downregulation of Gs alpha accounts for pulmonary beta(2)-adrenoceptor desensitization in vivo", J CLIN INV, 106(1), 2000, pp. 125-135
93. Thomas, SR; Kharitonov, SA; Scott, SF; Hodson, ME; Barnes, PJ
    Nasal and exhaled nitric oxide is reduced in adult patients with cystic fibrosis and does not correlate with cystic fibrosis genotype
    CHEST
    
    S.R. Thomas et al., "Nasal and exhaled nitric oxide is reduced in adult patients with cystic fibrosis and does not correlate with cystic fibrosis genotype", CHEST, 117(4), 2000, pp. 1085-1089
94. Barnes, PJ
    Mechanisms in COPD - Differences from asthma
    CHEST
    
    P.J. Barnes, "Mechanisms in COPD - Differences from asthma", CHEST, 117(2), 2000, pp. 10-14
95. Barnes, PJ
    The pharmacological properties of tiotropium
    CHEST
    
    P.J. Barnes, "The pharmacological properties of tiotropium", CHEST, 117(2), 2000, pp. 63-66
96. Barnes, PJ
    Polymer - or plastic?
    CHEMISTRY & INDUSTRY
    
    P.J. Barnes, "Polymer - or plastic?", CHEM IND L, (19), 2000, pp. 628-628
97. Meja, KK; Seldon, PM; Nasuhara, Y; Ito, K; Barnes, PJ; Lindsay, MA; Giembycz, MA
    p38 MAP kinase and MKK-1 co-operate in the generation of GM-CSF from LPS-stimulated human monocytes by an NF-kappa B-independent mechanism
    BRITISH JOURNAL OF PHARMACOLOGY
    
    K.K. Meja et al., "p38 MAP kinase and MKK-1 co-operate in the generation of GM-CSF from LPS-stimulated human monocytes by an NF-kappa B-independent mechanism", BR J PHARM, 131(6), 2000, pp. 1143-1153
98. Koch, A; Nasuhara, Y; Barnes, PJ; Lindsay, MA; Giembycz, MA
    Extracellular signal-regulated kinase 1/2 control Ca2+-independent force development in histamine-stimulated bovine tracheal smooth muscle
    BRITISH JOURNAL OF PHARMACOLOGY
    
    A. Koch et al., "Extracellular signal-regulated kinase 1/2 control Ca2+-independent force development in histamine-stimulated bovine tracheal smooth muscle", BR J PHARM, 131(5), 2000, pp. 981-989
99. Spicuzza, L; Haddad, EB; Birrell, M; Ling, A; Clarke, D; Venkatesan, P; Barnes, PJ; Belvisi, MG
    Characterization of the effects of cannabinoids on guinea-pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves
    BRITISH JOURNAL OF PHARMACOLOGY
    
    L. Spicuzza et al., "Characterization of the effects of cannabinoids on guinea-pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves", BR J PHARM, 130(7), 2000, pp. 1720-1726
100. Newton, R; Cambridge, L; Hart, LA; Stevens, DA; Lindsay, MA; Barnes, PJ
     The MAP kinase inhibitors, PD098059, UO126 and SB203580, inhibit IL-1 beta-dependent PGE(2) release via mechanistically distinct processes
     BRITISH JOURNAL OF PHARMACOLOGY
     
     R. Newton et al., "The MAP kinase inhibitors, PD098059, UO126 and SB203580, inhibit IL-1 beta-dependent PGE(2) release via mechanistically distinct processes", BR J PHARM, 130(6), 2000, pp. 1353-1361