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1. Overbeeke, PLA; Koops, BC; Verheij, HM; Slotboom, AJ; Egmond, MR; Jongejan, JA; Heijnen, JJ
   Activity and enantioselectivity of modified lipases in organic solvents
   BIOCATALYSIS AND BIOTRANSFORMATION
   
   P.L.A. Overbeeke et al., "Activity and enantioselectivity of modified lipases in organic solvents", BIOCATAL B, 18(1), 2000, pp. 59-77
2. Kingma, RL; Fragiathaki, M; Snijder, HJ; Dijkstra, BW; Verheij, HM; Dekker, N; Egmond, MR
   Unusual catalytic triad of Escherichia coli outer membrane phospholipase A
   BIOCHEMISTRY
   
   R.L. Kingma et al., "Unusual catalytic triad of Escherichia coli outer membrane phospholipase A", BIOCHEM, 39(33), 2000, pp. 10017-10022
3. Yu, BZ; Janssen, MJW; Verheij, HM; Jain, MK
   Control of the chemical step by leucine-31 of pancreatic phospholipase A(2)
   BIOCHEMISTRY
   
   B.Z. Yu et al., "Control of the chemical step by leucine-31 of pancreatic phospholipase A(2)", BIOCHEM, 39(19), 2000, pp. 5702-5711
4. Janssen, MJW; van de Wiel, WAEC; Beiboer, SHW; van Kampen, MD; Verheij, HM; Slotboom, AJ; Egmond, MR
   Catalytic role of the active site histidine of porcine pancreatic phospholipase A2 probed by the variants H48Q, H48N and H48K
   PROTEIN ENGINEERING
   
   M.J.W. Janssen et al., "Catalytic role of the active site histidine of porcine pancreatic phospholipase A2 probed by the variants H48Q, H48N and H48K", PROTEIN ENG, 12(6), 1999, pp. 497-503
5. Koops, BC; Papadimou, E; Verheij, HM; Slotboom, AJ; Egmond, MR
   Activity and stability of chemically modified Candida antarctica lipase B adsorbed on solid supports
   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
   
   B.C. Koops et al., "Activity and stability of chemically modified Candida antarctica lipase B adsorbed on solid supports", APPL MICR B, 52(6), 1999, pp. 791-796
6. Koops, BC; Verheij, HM; Slotboom, AJ; Egmond, MR
   Effect of chemical modification on the activity of lipases in organic solvents
   ENZYME AND MICROBIAL TECHNOLOGY
   
   B.C. Koops et al., "Effect of chemical modification on the activity of lipases in organic solvents", ENZYME MICR, 25(7), 1999, pp. 622-631
7. Snijder, HJ; Ubarretxena-Belandia, I; Blaauw, M; Kalk, KH; Verheij, HM; Egmond, MR; Dekker, N; Dijkstra, BW
   Structural evidence for dimerization-regulated activation of an integral membrane phospholipase
   NATURE
   
   H.J. Snijder et al., "Structural evidence for dimerization-regulated activation of an integral membrane phospholipase", NATURE, 401(6754), 1999, pp. 717-721
8. Dekker, N; Tommassen, J; Verheij, HM
   Bacteriocin release protein triggers dimerization of outer membrane phospholipase A in vivo
   JOURNAL OF BACTERIOLOGY
   
   N. Dekker et al., "Bacteriocin release protein triggers dimerization of outer membrane phospholipase A in vivo", J BACT, 181(10), 1999, pp. 3281-3283
9. Janssen, MJW; Burghout, PJ; Verheij, HM; Slotboom, AJ; Egmond, MR
   Introduction of a C-terminal aromatic sequence from snake venom phospholipases A(2) into the porcine pancreatic isozyme dramatically changes the interfacial kinetics
   EUROPEAN JOURNAL OF BIOCHEMISTRY
   
   M.J.W. Janssen et al., "Introduction of a C-terminal aromatic sequence from snake venom phospholipases A(2) into the porcine pancreatic isozyme dramatically changes the interfacial kinetics", EUR J BIOCH, 263(3), 1999, pp. 782-788
10. Janssen, MJW; Verheij, HM; Slotboom, AJ; Egmond, MR
    Engineering the disulphide bond patterns of secretory phospholipases A2 into porcine pancreatic isozyme - The effects on folding, stability and enzymatic properties
    EUROPEAN JOURNAL OF BIOCHEMISTRY
    
    M.J.W. Janssen et al., "Engineering the disulphide bond patterns of secretory phospholipases A2 into porcine pancreatic isozyme - The effects on folding, stability and enzymatic properties", EUR J BIOCH, 261(1), 1999, pp. 197-207
11. Ubarretxena-Belandia, I; Cox, RC; Dijkman, R; Egmond, MR; Verheij, HM; Dekker, N
    Half-of-the-sites reactivity of outer-membrane phospholipase A against an active-site-directed inhibitor
    EUROPEAN JOURNAL OF BIOCHEMISTRY
    
    I. Ubarretxena-Belandia et al., "Half-of-the-sites reactivity of outer-membrane phospholipase A against an active-site-directed inhibitor", EUR J BIOCH, 260(3), 1999, pp. 794-800
12. Flipsen, JAC; van Schaick, MA; Dijkman, R; van der Hijden, HTWM; Verheij, HM; Egmond, MR
    Interfacial binding of cutinase rather than its catalytic activity determines the steady state interfacial tension during oil drop lipid hydrolysis
    CHEMISTRY AND PHYSICS OF LIPIDS
    
    J.A.C. Flipsen et al., "Interfacial binding of cutinase rather than its catalytic activity determines the steady state interfacial tension during oil drop lipid hydrolysis", CHEM PHYS L, 97(2), 1999, pp. 181-191
13. van Kampen, M; Verheij, HM; Egmond, MR
    Modifying the substrate specificity of staphylococcal lipases
    BIOCHEMISTRY
    
    M. van Kampen et al., "Modifying the substrate specificity of staphylococcal lipases", BIOCHEM, 38(29), 1999, pp. 9524-9532
14. Ubarretxena-Belandia, I; Hozeman, L; van der Brink-van der Laan, E; Pap, EHM; Egmond, MR; Verheij, HM; Dekker, N
    Outer membrane phospholipase A is dimeric in phospholipid bilayers: A cross-linking and fluorescence resonance energy transfer study
    BIOCHEMISTRY
    
    I. Ubarretxena-Belandia et al., "Outer membrane phospholipase A is dimeric in phospholipid bilayers: A cross-linking and fluorescence resonance energy transfer study", BIOCHEM, 38(22), 1999, pp. 7398-7405
15. Prompers, JJ; van Noorloos, B; Mannesse, MLM; Groenewegen, A; Egmond, MR; Verheij, HM; Hilbers, CW; Pepermans, HAM
    NMR studies of Fusarium solani pisi cutinase in complex with phosphonate inhibitors
    BIOCHEMISTRY
    
    J.J. Prompers et al., "NMR studies of Fusarium solani pisi cutinase in complex with phosphonate inhibitors", BIOCHEM, 38(19), 1999, pp. 5982-5994
16. Simons, JWFA; Cox, RC; Egmond, MR; Verheij, HM
    Rational design of alpha-keto triglyceride analogues as inhibitors for Staphylococcus hyicus lipase
    BIOCHEMISTRY
    
    J.W.F.A. Simons et al., "Rational design of alpha-keto triglyceride analogues as inhibitors for Staphylococcus hyicus lipase", BIOCHEM, 38(19), 1999, pp. 6346-6351
17. Simons, JWFA; van Kampen, MD; Ubarretxena-Belandia, I; Cox, RC; dos Santos, CMA; Egmond, MR; Verheij, HM
    Identification of a calcium binding site in Staphylococcus hyicus lipase: Generation of calcium-independent variants
    BIOCHEMISTRY
    
    J.W.F.A. Simons et al., "Identification of a calcium binding site in Staphylococcus hyicus lipase: Generation of calcium-independent variants", BIOCHEM, 38(1), 1999, pp. 2-10
18. BOEKEMA EJ; STUART M; KONING RI; KEEGSTRA W; BRISSON A; VERHEIJ HM; DEKKER N
    A 7.4-ANGSTROM PROJECTION STRUCTURE OF OUTER-MEMBRANE PHOSPHOLIPASE-AFROM ESCHERICHIA-COLI BY ELECTRON CRYSTALLOGRAPHY
    Journal of structural biology (Print)
    
    E.J. Boekema et al., "A 7.4-ANGSTROM PROJECTION STRUCTURE OF OUTER-MEMBRANE PHOSPHOLIPASE-AFROM ESCHERICHIA-COLI BY ELECTRON CRYSTALLOGRAPHY", Journal of structural biology (Print), 123(1), 1998, pp. 67-71
19. Brok, RGPM; Boots, AP; Dekker, N; Verheij, HM; Tommassen, J
    Sequence comparison of outer membrane phospholipases A: implications for structure and for the catalytic mechanism
    RESEARCH IN MICROBIOLOGY
    
    R.G.P.M. Brok et al., "Sequence comparison of outer membrane phospholipases A: implications for structure and for the catalytic mechanism", RES MICROB, 149(10), 1998, pp. 703-710
20. LANG DA; MANNESSE MLM; DEHAAS GH; VERHEIJ HM; DIJKSTRA BW
    STRUCTURAL BASIS OF THE CHIRAL SELECTIVITY OF PSEUDOMONAS-CEPACIA LIPASE
    European journal of biochemistry
    
    D.A. Lang et al., "STRUCTURAL BASIS OF THE CHIRAL SELECTIVITY OF PSEUDOMONAS-CEPACIA LIPASE", European journal of biochemistry, 254(2), 1998, pp. 333-340
21. SIMONS JWFA; VANKAMPEN MD; RIEL S; GOTZ F; EGMOND MR; VERHEIJ HM
    CLONING, PURIFICATION AND CHARACTERIZATION OF THE LIPASE FROM STAPHYLOCOCCUS-EPIDERMIDIS - COMPARISON OF THE SUBSTRATE SELECTIVITY WITH THOSE OF OTHER MICROBIAL LIPASES
    European journal of biochemistry
    
    J.W.F.A. Simons et al., "CLONING, PURIFICATION AND CHARACTERIZATION OF THE LIPASE FROM STAPHYLOCOCCUS-EPIDERMIDIS - COMPARISON OF THE SUBSTRATE SELECTIVITY WITH THOSE OF OTHER MICROBIAL LIPASES", European journal of biochemistry, 253(3), 1998, pp. 675-683
22. GOTZ F; VERHEIJ HM; ROSENSTEIN R
    STAPHYLOCOCCAL LIPASES - MOLECULAR CHARACTERIZATION, SECRETION, AND PROCESSING
    Chemistry and physics of lipids
    
    F. Gotz et al., "STAPHYLOCOCCAL LIPASES - MOLECULAR CHARACTERIZATION, SECRETION, AND PROCESSING", Chemistry and physics of lipids, 93(1-2), 1998, pp. 15-25
23. SIMONS JWFA; GOTZ F; EGMOND MR; VERHEIJ HM
    BIOCHEMICAL-PROPERTIES OF STAPHYLOCOCCAL (PHOSPHO)LIPASES
    Chemistry and physics of lipids
    
    J.W.F.A. Simons et al., "BIOCHEMICAL-PROPERTIES OF STAPHYLOCOCCAL (PHOSPHO)LIPASES", Chemistry and physics of lipids, 93(1-2), 1998, pp. 27-37
24. VANKAMPEN MD; SIMONS JWFA; DEKKER N; EGMOND MR; VERHEIJ HM
    THE PHOSPHOLIPASE-ACTIVITY OF STAPHYLOCOCCUS-HYICUS LIPASE STRONGLY DEPENDS ON A SINGLE SER TO VAL MUTATION
    Chemistry and physics of lipids
    
    M.D. Vankampen et al., "THE PHOSPHOLIPASE-ACTIVITY OF STAPHYLOCOCCUS-HYICUS LIPASE STRONGLY DEPENDS ON A SINGLE SER TO VAL MUTATION", Chemistry and physics of lipids, 93(1-2), 1998, pp. 39-45
25. Flipsen, JAC; Kramer, RA; van Duijnhoven, JPM; van der Hijden, HTWM; Egmond, MR; Verheij, HM
    Cutinase binding and activity at the triolein-water interface monitored byoil drop tensiometry
    CHEMISTRY AND PHYSICS OF LIPIDS
    
    J.A.C. Flipsen et al., "Cutinase binding and activity at the triolein-water interface monitored byoil drop tensiometry", CHEM PHYS L, 95(2), 1998, pp. 169-180
26. UBARRETXENABELANDIA I; BOOTS JWP; VERHEIJ HM; DEKKER N
    ROLE OF THE COFACTOR CALCIUM IN THE ACTIVATION OF OUTER-MEMBRANE PHOSPHOLIPASE-A
    Biochemistry (Easton)
    
    I. Ubarretxenabelandia et al., "ROLE OF THE COFACTOR CALCIUM IN THE ACTIVATION OF OUTER-MEMBRANE PHOSPHOLIPASE-A", Biochemistry (Easton), 37(45), 1998, pp. 16011-16018
27. VANKAMPEN MD; DEKKER N; EGMOND MR; VERHEIJ HM
    SUBSTRATE-SPECIFICITY OF STAPHYLOCOCCUS-HYICUS LIPASE AND STAPHYLOCOCCUS-AUREUS LIPASE AS STUDIED BY IN-VIVO CHIMERAGENESIS
    Biochemistry
    
    M.D. Vankampen et al., "SUBSTRATE-SPECIFICITY OF STAPHYLOCOCCUS-HYICUS LIPASE AND STAPHYLOCOCCUS-AUREUS LIPASE AS STUDIED BY IN-VIVO CHIMERAGENESIS", Biochemistry, 37(10), 1998, pp. 3459-3466
28. PUNGERCAR J; VUCEMILO N; FAURE G; BON C; VERHEIJ HM; GUBENSEK F; KRIZAJ I
    AMMODYTIN-L, AN INACTIVE PHOSPHOLIPASE-A(2) HOMOLOG WITH MYOTOXICITY IN MICE, BINDS TO THE PRESYNAPTIC ACCEPTOR OF THE BETA-NEUROTOXIC AMMODYTOXIN-C IN TORPEDO - AN INDICATION FOR A PHOSPHOLIPASE A(2) ACTIVITY-INDEPENDENT MECHANISM OF ACTION OF BETA-NEUROTOXINS IN FISH
    Biochemical and biophysical research communications
    
    J. Pungercar et al., "AMMODYTIN-L, AN INACTIVE PHOSPHOLIPASE-A(2) HOMOLOG WITH MYOTOXICITY IN MICE, BINDS TO THE PRESYNAPTIC ACCEPTOR OF THE BETA-NEUROTOXIC AMMODYTOXIN-C IN TORPEDO - AN INDICATION FOR A PHOSPHOLIPASE A(2) ACTIVITY-INDEPENDENT MECHANISM OF ACTION OF BETA-NEUROTOXINS IN FISH", Biochemical and biophysical research communications, 244(2), 1998, pp. 514-518
29. SIMONS JWFA; BOOTS JWP; SLOTBOOM AJ; VERHEIJ HM
    THE (PHOSPHO)LIPASE FROM STAPHYLOCOCCUS-HYICUS - EXPRESSION IN ESCHERICHIA-COLI, LARGE-SCALE PURIFICATION AND APPLICATION IN ESTERIFICATIONREACTIONS
    Journal of molecular catalysis. B, Enzymatic
    
    J.W.F.A. Simons et al., "THE (PHOSPHO)LIPASE FROM STAPHYLOCOCCUS-HYICUS - EXPRESSION IN ESCHERICHIA-COLI, LARGE-SCALE PURIFICATION AND APPLICATION IN ESTERIFICATIONREACTIONS", Journal of molecular catalysis. B, Enzymatic, 3(1-4), 1997, pp. 13-23
30. LONGHI S; MANNESSE M; VERHEIJ HM; DEHAAS GH; EGMOND M; KNOOPSMOUTHUY E; CAMBILLAU C
    CRYSTAL-STRUCTURE OF CUTINASE COVALENTLY INHIBITED BY A TRIGLYCERIDE ANALOG
    Protein science
    
    S. Longhi et al., "CRYSTAL-STRUCTURE OF CUTINASE COVALENTLY INHIBITED BY A TRIGLYCERIDE ANALOG", Protein science, 6(2), 1997, pp. 275-286
31. SIMONS JWFA; COX RC; VERHEIJ HM
    RATIONAL DESIGN OF ALPHA-KETO ESTER INHIBITORS FOR LIPASES
    The FASEB journal
    
    J.W.F.A. Simons et al., "RATIONAL DESIGN OF ALPHA-KETO ESTER INHIBITORS FOR LIPASES", The FASEB journal, 11(9), 1997, pp. 1016-1016
32. MANNESSE MLM; DEHAAS GH; VANDERHIJDEN HTWM; EGMOND MR; VERHEIJ HM
    CHIRAL PREFERENCE OF CUTINASE IN THE REACTION WITH PHOSPHONATE INHIBITORS
    Biochemical Society transactions
    
    M.L.M. Mannesse et al., "CHIRAL PREFERENCE OF CUTINASE IN THE REACTION WITH PHOSPHONATE INHIBITORS", Biochemical Society transactions, 25(1), 1997, pp. 165-170
33. DEKKER N; TOMMASSEN J; LUSTIG A; ROSENBUSCH JP; VERHEIJ HM
    DIMERIZATION REGULATES THE ENZYMATIC-ACTIVITY OF ESCHERICHIA-COLI OUTER-MEMBRANE PHOSPHOLIPASE-A
    The Journal of biological chemistry
    
    N. Dekker et al., "DIMERIZATION REGULATES THE ENZYMATIC-ACTIVITY OF ESCHERICHIA-COLI OUTER-MEMBRANE PHOSPHOLIPASE-A", The Journal of biological chemistry, 272(6), 1997, pp. 3179-3184
34. MERCK KB; DECOCK H; VERHEIJ HM; TOMMASSEN J
    TOPOLOGY OF THE OUTER-MEMBRANE PHOSPHOLIPASE-A OF SALMONELLA-TYPHIMURIUM
    Journal of bacteriology
    
    K.B. Merck et al., "TOPOLOGY OF THE OUTER-MEMBRANE PHOSPHOLIPASE-A OF SALMONELLA-TYPHIMURIUM", Journal of bacteriology, 179(11), 1997, pp. 3443-3450
35. SIMONS JWFA; BOOTS JWP; KATS MP; SLOTBOOM AJ; EGMOND MR; VERHEIJ HM
    DISSECTING THE CATALYTIC MECHANISM OF STAPHYLOCOCCAL LIPASES USING CARBAMATE SUBSTRATES - CHAIN-LENGTH SELECTIVITY, INTERFACIAL ACTIVATION,AND COFACTOR DEPENDENCE
    Biochemistry
    
    J.W.F.A. Simons et al., "DISSECTING THE CATALYTIC MECHANISM OF STAPHYLOCOCCAL LIPASES USING CARBAMATE SUBSTRATES - CHAIN-LENGTH SELECTIVITY, INTERFACIAL ACTIVATION,AND COFACTOR DEPENDENCE", Biochemistry, 36(47), 1997, pp. 14539-14550
36. DIJKMAN R; BEIBOER SHW; VERHEIJ HM
    AN AFFINITY COLUMN FOR PHOSPHOLIPASE A(2) BASED ON IMMOBILIZED ACYLAMINOPHOSPHOLIPID ANALOGS
    Biochimica et biophysica acta, L. Lipids and lipid metabolism
    
    R. Dijkman et al., "AN AFFINITY COLUMN FOR PHOSPHOLIPASE A(2) BASED ON IMMOBILIZED ACYLAMINOPHOSPHOLIPID ANALOGS", Biochimica et biophysica acta, L. Lipids and lipid metabolism, 1347(1), 1997, pp. 1-8
37. BEIBOER SHW; VANDENBERG B; DEKKER N; COX RC; VERHEIJ HM
    INCORPORATION OF AN UNNATURAL AMINO-ACID IN THE ACTIVE-SITE OF PORCINE PANCREATIC PHOSPHOLIPASE A(2) - SUBSTITUTION OF HISTIDINE BY 1,2,4-TRIAZOLE-3-ALANINE YIELDS AN ENZYME WITH HIGH-ACTIVITY AT ACIDIC PH
    Protein engineering
    
    S.H.W. Beiboer et al., "INCORPORATION OF AN UNNATURAL AMINO-ACID IN THE ACTIVE-SITE OF PORCINE PANCREATIC PHOSPHOLIPASE A(2) - SUBSTITUTION OF HISTIDINE BY 1,2,4-TRIAZOLE-3-ALANINE YIELDS AN ENZYME WITH HIGH-ACTIVITY AT ACIDIC PH", Protein engineering, 9(4), 1996, pp. 345-352
38. SIMONS JWFA; ADAMS H; COX RC; DEKKER N; GOTZ F; SLOTBOOM AJ; VERHEIJ HM
    THE LIPASE FROM STAPHYLOCOCCUS-AUREUS - EXPRESSION IN ESCHERICHIA-COLI, LARGE-SCALE PURIFICATION AND COMPARISON OF SUBSTRATE-SPECIFICITY TOSTAPHYLOCOCCUS-HYICUS LIPASE
    European journal of biochemistry
    
    J.W.F.A. Simons et al., "THE LIPASE FROM STAPHYLOCOCCUS-AUREUS - EXPRESSION IN ESCHERICHIA-COLI, LARGE-SCALE PURIFICATION AND COMPARISON OF SUBSTRATE-SPECIFICITY TOSTAPHYLOCOCCUS-HYICUS LIPASE", European journal of biochemistry, 242(3), 1996, pp. 760-769
39. BEKKERS ACAPA; SLOTBOOM AJ; VANWILLIGEN G; AKKERMAN JWN; VERHEIJ HM
    TARGETING OF PORCINE PANCREATIC PHOSPHOLIPASE A(2) TO HUMAN PLATELETS- INTRODUCTION OF AN RGD SEQUENCE AND ACYL-GROUP BY CHEMICAL MODIFICATION
    European journal of biochemistry
    
    A.C.A.P.A. Bekkers et al., "TARGETING OF PORCINE PANCREATIC PHOSPHOLIPASE A(2) TO HUMAN PLATELETS- INTRODUCTION OF AN RGD SEQUENCE AND ACYL-GROUP BY CHEMICAL MODIFICATION", European journal of biochemistry, 238(1), 1996, pp. 70-76
40. MOUNIER C; FRANKEN PA; VERHEIJ HM; BON C
    ANTICOAGULANT EFFECT OF THE HUMAN SECRETORY PHOSPHOLIPASE A(2) ON BLOOD-PLASMA AND ON A CELL-FREE SYSTEM IS DUE TO A PHOSPHOLIPID-INDEPENDENT MECHANISM OF ACTION INVOLVING THE INHIBITION OF FACTOR VA
    European journal of biochemistry
    
    C. Mounier et al., "ANTICOAGULANT EFFECT OF THE HUMAN SECRETORY PHOSPHOLIPASE A(2) ON BLOOD-PLASMA AND ON A CELL-FREE SYSTEM IS DUE TO A PHOSPHOLIPID-INDEPENDENT MECHANISM OF ACTION INVOLVING THE INHIBITION OF FACTOR VA", European journal of biochemistry, 237(3), 1996, pp. 778-785
41. FLIPSEN JAC; VANDERHIJDEN HTWM; EGMOND MR; VERHEIJ HM
    ACTION OF CUTINASE AT THE TRIOLEIN-WATER INTERFACE - CHARACTERIZATIONOF INTERFACIAL EFFECTS DURING LIPID HYDROLYSIS USING THE OIL-DROP TENSIOMETER AS A TOOL TO STUDY LIPASE KINETICS
    Chemistry and physics of lipids
    
    J.A.C. Flipsen et al., "ACTION OF CUTINASE AT THE TRIOLEIN-WATER INTERFACE - CHARACTERIZATIONOF INTERFACIAL EFFECTS DURING LIPID HYDROLYSIS USING THE OIL-DROP TENSIOMETER AS A TOOL TO STUDY LIPASE KINETICS", Chemistry and physics of lipids, 84(2), 1996, pp. 105-115
42. BROK RGPM; BELANDIA IU; DEKKER N; TOMMASSEN J; VERHEIJ HM
    ESCHERICHIA-COLI OUTER-MEMBRANE PHOSPHOLIPASE-A - ROLE OF 2 SERINES IN ENZYMATIC-ACTIVITY
    Biochemistry
    
    R.G.P.M. Brok et al., "ESCHERICHIA-COLI OUTER-MEMBRANE PHOSPHOLIPASE-A - ROLE OF 2 SERINES IN ENZYMATIC-ACTIVITY", Biochemistry, 35(24), 1996, pp. 7787-7793
43. VANDENBERG B; TESSARI M; BOELENS R; DIJKMAN R; DEHAAS GH; KAPTEIN R; VERHEIJ HM
    NMR STRUCTURES OF PHOSPHOLIPASE A(2) REVEAL CONFORMATIONAL-CHANGES DURING INTERFACIAL ACTIVATION
    Nature structural biology
    
    B. Vandenberg et al., "NMR STRUCTURES OF PHOSPHOLIPASE A(2) REVEAL CONFORMATIONAL-CHANGES DURING INTERFACIAL ACTIVATION", Nature structural biology, 2(5), 1995, pp. 402-406
44. RANSAC S; BLAAUW M; DIJKSTRA BW; SLOTBOOM AJ; BOOTS JWP; VERHEIJ HM
    CRYSTALLIZATION AND PRELIMINARY-X-RAY ANALYSIS OF A LIPASE FROM STAPHYLOCOCCUS-HYICUS
    Journal of structural biology
    
    S. Ransac et al., "CRYSTALLIZATION AND PRELIMINARY-X-RAY ANALYSIS OF A LIPASE FROM STAPHYLOCOCCUS-HYICUS", Journal of structural biology, 114(2), 1995, pp. 153-155
45. VANDENBERG B; TESSARI M; BOELENS R; DIJKMAN R; KAPTEIN R; DEHAAS GH; VERHEIJ HM
    SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A(2) COMPLEXEDWITH MICELLES AND A COMPETITIVE INHIBITOR
    Journal of biomolecular NMR
    
    B. Vandenberg et al., "SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A(2) COMPLEXEDWITH MICELLES AND A COMPETITIVE INHIBITOR", Journal of biomolecular NMR, 5(2), 1995, pp. 110-121
46. BEKKERS ACAPA; VANDERVUURST H; VANWILLIGEN G; AKKERMAN JWN; VERHEIJ HM
    TARGETING OF PORCINE PANCREATIC PHOSPHOLIPASE A(2) TO HUMAN PLATELETS- INTRODUCTION OF AN RGD SEQUENCE BY GENETIC-ENGINEERING
    Thrombosis and haemostasis
    
    A.C.A.P.A. Bekkers et al., "TARGETING OF PORCINE PANCREATIC PHOSPHOLIPASE A(2) TO HUMAN PLATELETS- INTRODUCTION OF AN RGD SEQUENCE BY GENETIC-ENGINEERING", Thrombosis and haemostasis, 74(4), 1995, pp. 1138-1144
47. BEKKERS ACAPA; VANWILLIGEN G; VANDERVUURST H; SLOTBOOM AJ; AKKERMAN JWN; VERHEIJ HM
    TARGETING OF PORCINE PANCREATIC PHOSPHOLIPASE-A(2) TO ACTIVATED HUMANPLATELETS
    Thrombosis and haemostasis
    
    A.C.A.P.A. Bekkers et al., "TARGETING OF PORCINE PANCREATIC PHOSPHOLIPASE-A(2) TO ACTIVATED HUMANPLATELETS", Thrombosis and haemostasis, 73(6), 1995, pp. 1197-1197
48. VANDENBERG B; TESSARI M; DEHAAS GH; VERHEIJ HM; BOELENS R; KAPTEIN R
    SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A(2)
    EMBO journal
    
    B. Vandenberg et al., "SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A(2)", EMBO journal, 14(17), 1995, pp. 4123-4131
49. BOOTS JWP; VANDONGEN WD; VERHEIJ HM; DEHAAS GH; HAVERKAMP J; SLOTBOOM AJ
    IDENTIFICATION OF THE ACTIVE-SITE HISTIDINE IN STAPHYLOCOCCUS-HYICUS LIPASE USING CHEMICAL MODIFICATION AND MASS-SPECTROMETRY
    Biochimica et biophysica acta. Protein structure and molecular enzymology
    
    J.W.P. Boots et al., "IDENTIFICATION OF THE ACTIVE-SITE HISTIDINE IN STAPHYLOCOCCUS-HYICUS LIPASE USING CHEMICAL MODIFICATION AND MASS-SPECTROMETRY", Biochimica et biophysica acta. Protein structure and molecular enzymology, 1248(1), 1995, pp. 27-34
50. KISHINO J; KAWAMOTO K; ISHIZAKI J; VERHEIJ HM; OHARA O; ARITA H
    PANCREATIC-TYPE PHOSPHOLIPASE A(2), ACTIVATES PROSTAGLANDIN E(2) PRODUCTION IN RAT MESANGIAL CELLS BY RECEPTOR-BINDING REACTION
    Journal of Biochemistry
    
    J. Kishino et al., "PANCREATIC-TYPE PHOSPHOLIPASE A(2), ACTIVATES PROSTAGLANDIN E(2) PRODUCTION IN RAT MESANGIAL CELLS BY RECEPTOR-BINDING REACTION", Journal of Biochemistry, 117(2), 1995, pp. 420-424
51. BLAAUW M; DEKKER N; VERHEIJ HM; KALK KH; DIJKSTRA BW
    CRYSTALLIZATION AND PRELIMINARY-X-RAY ANALYSIS OF OUTER-MEMBRANE PHOSPHOLIPASE-A FROM ESCHERICHIA-COLI
    FEBS letters
    
    M. Blaauw et al., "CRYSTALLIZATION AND PRELIMINARY-X-RAY ANALYSIS OF OUTER-MEMBRANE PHOSPHOLIPASE-A FROM ESCHERICHIA-COLI", FEBS letters, 373(1), 1995, pp. 10-12
52. BROK RGPM; DEKKER N; GERRITS N; VERHEIJ HM; TOMMASSEN J
    A CONSERVED HISTIDINE RESIDUE OF ESCHERICHIA-COLI OUTER-MEMBRANE PHOSPHOLIPASE-A IS IMPORTANT FOR ACTIVITY
    European journal of biochemistry
    
    R.G.P.M. Brok et al., "A CONSERVED HISTIDINE RESIDUE OF ESCHERICHIA-COLI OUTER-MEMBRANE PHOSPHOLIPASE-A IS IMPORTANT FOR ACTIVITY", European journal of biochemistry, 234(3), 1995, pp. 934-938
53. DEKKER N; MERCK K; TOMMASSEN J; VERHEIJ HM
    IN-VITRO FOLDING OF ESCHERICHIA-COLI OUTER-MEMBRANE PHOSPHOLIPASE-A
    European journal of biochemistry
    
    N. Dekker et al., "IN-VITRO FOLDING OF ESCHERICHIA-COLI OUTER-MEMBRANE PHOSPHOLIPASE-A", European journal of biochemistry, 232(1), 1995, pp. 214-219
54. BEIBOER SHW; FRANKEN PA; COX RC; VERHEIJ HM
    AN EXTENDED BINDING POCKET DETERMINES THE POLAR HEAD GROUP SPECIFICITY OF PORCINE PANCREATIC PHOSPHOLIPASE A(2)
    European journal of biochemistry
    
    S.H.W. Beiboer et al., "AN EXTENDED BINDING POCKET DETERMINES THE POLAR HEAD GROUP SPECIFICITY OF PORCINE PANCREATIC PHOSPHOLIPASE A(2)", European journal of biochemistry, 231(3), 1995, pp. 747-753
55. NIKOLEIT K; ROSENSTEIN R; VERHEIJ HM; GOTZ F
    COMPARATIVE BIOCHEMICAL AND MOLECULAR ANALYSIS OF THE STAPHYLOCOCCUS-HYICUS, STAPHYLOCOCCUS-AUREUS AND A HYBRID LIPASE - INDICATION FOR A C-TERMINAL PHOSPHOLIPASE DOMAIN
    European journal of biochemistry
    
    K. Nikoleit et al., "COMPARATIVE BIOCHEMICAL AND MOLECULAR ANALYSIS OF THE STAPHYLOCOCCUS-HYICUS, STAPHYLOCOCCUS-AUREUS AND A HYBRID LIPASE - INDICATION FOR A C-TERMINAL PHOSPHOLIPASE DOMAIN", European journal of biochemistry, 228(3), 1995, pp. 732-738
56. MANNESSE MLM; COX RC; KOOPS BC; VERHEIJ HM; DEHAAS GH; EGMOND MR; VANDERHIJDEN HTWM; DEVLIEG J
    CUTINASE FROM FUSARIUM-SOLANI PISI HYDROLYZING TRIGLYCERIDE ANALOGS -EFFECT OF ACYL-CHAIN LENGTH AND POSITION IN THE SUBSTRATE MOLECULE ONACTIVITY AND ENANTIOSELECTIVITY
    Biochemistry
    
    M.L.M. Mannesse et al., "CUTINASE FROM FUSARIUM-SOLANI PISI HYDROLYZING TRIGLYCERIDE ANALOGS -EFFECT OF ACYL-CHAIN LENGTH AND POSITION IN THE SUBSTRATE MOLECULE ONACTIVITY AND ENANTIOSELECTIVITY", Biochemistry, 34(19), 1995, pp. 6400-6407
57. MANNESSE MLM; BOOTS JWP; DIJKMAN R; SLOTBOOM AJ; VANDERHIJDEN HTWV; EGMOND MR; VERHEIJ HM; DEHAAS GH
    PHOSPHONATE ANALOGS OF TRIACYLGLYCEROLS ARE POTENT INHIBITORS OF LIPASE
    Biochimica et biophysica acta, L. Lipids and lipid metabolism
    
    M.L.M. Mannesse et al., "PHOSPHONATE ANALOGS OF TRIACYLGLYCEROLS ARE POTENT INHIBITORS OF LIPASE", Biochimica et biophysica acta, L. Lipids and lipid metabolism, 1259(1), 1995, pp. 56-64
58. DEHAAS GH; DIJKMAN R; BOOTS JWP; VERHEIJ HM
    COMPETITIVE-INHIBITION OF LIPOLYTIC ENZYMES .11. ESTIMATION OF THE INTERFACIAL DISSOCIATION-CONSTANTS OF PORCINE PANCREATIC PHOSPHOLIPASE A(2) FOR SUBSTRATE AND INHIBITOR IN THE ABSENCE OF DETERGENTS
    Biochimica et biophysica acta, L. Lipids and lipid metabolism
    
    G.H. Dehaas et al., "COMPETITIVE-INHIBITION OF LIPOLYTIC ENZYMES .11. ESTIMATION OF THE INTERFACIAL DISSOCIATION-CONSTANTS OF PORCINE PANCREATIC PHOSPHOLIPASE A(2) FOR SUBSTRATE AND INHIBITOR IN THE ABSENCE OF DETERGENTS", Biochimica et biophysica acta, L. Lipids and lipid metabolism, 1257(2), 1995, pp. 87-95
59. TJEENK ML; BULSINK YBM; SLOTBOOM AJ; VERHEIJ HM; DEHAAS GH; DEMLEITNER G; GOTZ F
    INACTIVATION OF STAPHYLOCOCCUS-HYICUS LIPASE BY HEXADECYLSULFONYL FLUORIDE - EVIDENCE FOR AN ACTIVE-SITE SERINE
    Protein engineering
    
    M.L. Tjeenk et al., "INACTIVATION OF STAPHYLOCOCCUS-HYICUS LIPASE BY HEXADECYLSULFONYL FLUORIDE - EVIDENCE FOR AN ACTIVE-SITE SERINE", Protein engineering, 7(4), 1994, pp. 579-583
60. BROK RGPM; BRINKMAN E; VANBOXTEL R; BEKKERS ACAPA; VERHEIJ HM; TOMMASSEN J
    MOLECULAR CHARACTERIZATION OF ENTEROBACTERIAL PLDA GENES ENCODING OUTER-MEMBRANE PHOSPHOLIPASE-A
    Journal of bacteriology
    
    R.G.P.M. Brok et al., "MOLECULAR CHARACTERIZATION OF ENTEROBACTERIAL PLDA GENES ENCODING OUTER-MEMBRANE PHOSPHOLIPASE-A", Journal of bacteriology, 176(3), 1994, pp. 861-870
61. MOUNIER C; VARGAFTIG BB; FRANKEN PA; VERHEIJ HM; BON C; TOUQUI L
    PLATELET SECRETORY PHOSPHOLIPASE A(2) FAILS TO INDUCE RABBIT PLATELETACTIVATION AND TO RELEASE ARACHIDONIC-ACID IN CONTRAST WITH VENOM PHOSPHOLIPASES A(2)
    Biochimica et biophysica acta, L. Lipids and lipid metabolism
    
    C. Mounier et al., "PLATELET SECRETORY PHOSPHOLIPASE A(2) FAILS TO INDUCE RABBIT PLATELETACTIVATION AND TO RELEASE ARACHIDONIC-ACID IN CONTRAST WITH VENOM PHOSPHOLIPASES A(2)", Biochimica et biophysica acta, L. Lipids and lipid metabolism, 1214(1), 1994, pp. 88-96
62. DIJKMAN R; COX R; VANDENBERG L; VERHEIJ HM; DEHAAS GH
    COMPETITIVE-INHIBITION OF LIPOLYTIC ENZYMES .10. FURTHER DELINEATION OF THE ACTIVE-SITE OF PANCREATIC PHOSPHOLIPASES A(2) FROM PIG, OX AND HORSE BY COMPARING THE INHIBITORY POWER OF A NUMBER OF (R)-2-ACYLAMINOPHOSPHOLIPID ANALOGS
    Biochimica et biophysica acta, L. Lipids and lipid metabolism
    
    R. Dijkman et al., "COMPETITIVE-INHIBITION OF LIPOLYTIC ENZYMES .10. FURTHER DELINEATION OF THE ACTIVE-SITE OF PANCREATIC PHOSPHOLIPASES A(2) FROM PIG, OX AND HORSE BY COMPARING THE INHIBITORY POWER OF A NUMBER OF (R)-2-ACYLAMINOPHOSPHOLIPID ANALOGS", Biochimica et biophysica acta, L. Lipids and lipid metabolism, 1212(1), 1994, pp. 50-58
63. THUNNISSEN MMGM; FRANKEN PA; DEHAAS GH; DRENTH J; KALK KH; VERHEIJ HM; DIJKSTRA BW
    CRYSTAL-STRUCTURE OF A PORCINE PANCREATIC PHOSPHOLIPASE-A2 MUTANT - ALARGE CONFORMATIONAL CHANGE CAUSED BY THE F63V POINT MUTATION
    Journal of Molecular Biology
    
    M.M.G.M. Thunnissen et al., "CRYSTAL-STRUCTURE OF A PORCINE PANCREATIC PHOSPHOLIPASE-A2 MUTANT - ALARGE CONFORMATIONAL CHANGE CAUSED BY THE F63V POINT MUTATION", Journal of Molecular Biology, 232(3), 1993, pp. 839-855
64. LUGTIGHEID RB; NICOLAES GAF; VELDHUIZEN EJA; SLOTBOOM AJ; VERHEIJ HM; DEHAAS GH
    ACYLATION OF PORCINE PANCREATIC PHOSPHOLIPASE-A2 INFLUENCES PENETRATION AND SUBSTRATE HEADGROUP BINDING, DEPENDING ON THE POSITION OF THE ACYLATED LYSINE IN THE ENZYME MOLECULE
    European journal of biochemistry
    
    R.B. Lugtigheid et al., "ACYLATION OF PORCINE PANCREATIC PHOSPHOLIPASE-A2 INFLUENCES PENETRATION AND SUBSTRATE HEADGROUP BINDING, DEPENDING ON THE POSITION OF THE ACYLATED LYSINE IN THE ENZYME MOLECULE", European journal of biochemistry, 216(2), 1993, pp. 519-525
65. VINCENT M; DEVEER AM; DEHAAS GH; VERHEIJ HM; GALLAY J
    STEREOSPECIFICITY OF THE INTERACTION OF PORCINE PANCREATIC PHOSPHOLIPASE-A(2) WITH MICELLAR AND MONOMERIC INHIBITORS - A TIME-RESOLVED FLUORESCENCE STUDY OF THE TRYPTOPHAN RESIDUE
    European journal of biochemistry
    
    M. Vincent et al., "STEREOSPECIFICITY OF THE INTERACTION OF PORCINE PANCREATIC PHOSPHOLIPASE-A(2) WITH MICELLAR AND MONOMERIC INHIBITORS - A TIME-RESOLVED FLUORESCENCE STUDY OF THE TRYPTOPHAN RESIDUE", European journal of biochemistry, 215(3), 1993, pp. 531-539
66. DEHAAS GH; DIJKMAN R; LUGTIGHEID RB; DEKKER N; VANDENBERG L; EGMOND MR; VERHEIJ HM
    COMPETITIVE-INHIBITION OF LIPOLYTIC ENZYMES .9. A COMPARATIVE-STUDY ON THE INHIBITION OF PANCREATIC PHOSPHOLIPASES-A(2) FROM DIFFERENT SOURCES BY (R)-2-ACYLAMINO PHOSPHOLIPID ANALOGS
    Biochimica et biophysica acta
    
    G.H. Dehaas et al., "COMPETITIVE-INHIBITION OF LIPOLYTIC ENZYMES .9. A COMPARATIVE-STUDY ON THE INHIBITION OF PANCREATIC PHOSPHOLIPASES-A(2) FROM DIFFERENT SOURCES BY (R)-2-ACYLAMINO PHOSPHOLIPID ANALOGS", Biochimica et biophysica acta, 1167(3), 1993, pp. 281-288