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    1. Venkatachalam, TK; Sudbeck, EA; Mao, C; Uckun, FM
      Anti-HIV activity of aromatic and heterocyclic thiazolyl thiourea compounds

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    2. Chen, CL; Venkatachalam, TK; Zhu, ZH; Uckun, FM
      In vivo pharmacokinetics and metabolism of anti-human immunodeficiency virus agent D4T-5 '-[P-bromophenyl methoxyalaninyl phosphate] (sampidine) in mice

      DRUG METABOLISM AND DISPOSITION
    3. Venkatachalam, TK; Sudbeck, EA; Uckun, FM
      Regiospecific synthesis, X-ray crystal structure and biological activitiesof 5-bromothiophenethyl thioureas

      TETRAHEDRON LETTERS
    4. D'Cruz, OJ; Venkatachalam, TK; Uckun, FM
      Thymidine kinase-independent intracellular delivery of bioactive nucleotides by aryl phosphate derivatives of bromo-methoxy zidovudine (compounds WHI-05 and WHI-07) in normal human female genital tract epithelial cells and sperm

      BIOLOGY OF REPRODUCTION
    5. Chen, CL; Venkatachalam, TK; Waurzyniak, B; Chelstrom, L; Uckun, FM
      In vivo toxicity, pharmacokinetic features and tissue distribution of N-[2-(2,5-dimethoxyphenylethyl)]-N '-[2-(5-bromopyridyl)]-thiourea (HI-236), a potent non-nucleoside inhibitor of HIV-1 reverse transcriptase

      ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
    6. Venkatachalam, TK; Sudbeck, EA; Mao, C; Uckun, FM
      Stereochemistry of halopyridyl and thiazolyl thiourea compounds is a majordeterminant of their potency as nonnucleoside inhibitors of HIV-1 reverse transcriptase

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    7. Dong, YH; Venkatachalam, TK; Narla, RK; Trieu, VN; Sudbeck, EA; Uckun, FM
      Antioxidant function of phenethyl-5-bromo-pyridyl thiourea compounds with potent anti-HIV activity

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    8. Venkatachalam, TK; Sudbeck, EA; Mao, C; Uckun, FM
      Piperidinylethyl, phenoxyethyl and fluoroethyl bromopyridyl thiourea compounds with potent anti-HIV activity

      ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
    9. Uckun, FM; Mao, C; Pendergrass, S; Maher, D; Zhu, D; Tuel-Ahlgren, L; Venkatachalam, TK
      N-[2-(4-methylphenyl)ethyl]-N '-[2-(5-bromopyridyl)]-thiourea as a potent inhibitor of NNRTI-resistant and multidrug-resistant human immunodeficiencyvirus type 1

      ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
    10. Venkatachalam, TK; D'Cruz, OJ; Uckun, FM
      Importance of the alanine methyl ester side chain for the biological activity profile of dual-function phenyl phosphate derivatives of bromo-methoxy-zidovudine

      ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
    11. Mzengeza, S; Venkatachalam, TK; Diksic, M
      Stereospecific synthesis of alpha-methylated amino acids

      AMINO ACIDS
    12. Buncel, E; Venkatachalam, TK
      Carbanion mechanisms XXI. Solution acidity of triphenylsilane

      JOURNAL OF ORGANOMETALLIC CHEMISTRY
    13. D'Cruz, OJ; Venkatachalam, TK; Uckun, FM
      Novel thiourea compounds as dual-function microbicides

      BIOLOGY OF REPRODUCTION
    14. D'Cruz, OJ; Venkatachalam, TK; Uckun, FM
      Structural requirements for potent human spermicidal activity of dual-function aryl phosphate derivative of bromo-methoxy zidovudine (Compound WHI-07)

      BIOLOGY OF REPRODUCTION
    15. Mao, C; Sudbeck, EA; Venkatachalam, TK; Uckun, FM
      Structure-based drug design of non-nucleoside inhibitors for wild-type anddrug-resistant: HIV reverse transcriptase

      BIOCHEMICAL PHARMACOLOGY
    16. Kurinov, IV; Rajamohan, F; Venkatachalam, TK; Uckun, FM
      X-ray crystallographic analysis of the structural basis for the interaction of pokeweed antiviral protein with guanine residues of ribosomal RNA

      PROTEIN SCIENCE
    17. Uckun, FM; Pendergrass, S; Maher, D; Zhu, D; Tuel-Ahlgren, L; Mao, C; Venkatachalam, TK
      N '-[2-(2-thiophene)ethyl]-N '-[2-(5-bromopyridyl)] thiourea as a potent inhibitor of NNI-resistant and multidrug-resistant human immunodeficiency virus-1

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    18. Uckun, FM; Mao, C; Pendergrass, S; Maher, D; Zhu, D; Tuel-Ahlgren, L; Venkatachalam, TK
      N-[2-(1-cyclohexenyl)ethyl]-N '-[2-(5-bromopyridyl)]-thiourea and N '-[2-(1-cyclohexenyl)ethyl]-N '-[2-(5-chloropyridyl)]- thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    19. Mao, C; Sudbeck, EA; Venkatachalam, TK; Uckun, FM
      Rational design of N-[2-(2,5-dimethoxyphenylethyl)]-N '-[2-(5-bromopyridyl)]-thiourea (HI-236) as a potent non-nucleoside inhibitor of drug-resistanthuman immunodeficiency virus

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    20. Mao, C; Sudbeck, EA; Venkatachalam, TK; Uckun, FM
      Structure-based design of non-nucleoside reverse transcriptase inhibitors of drug-resistant human immunodeficiency virus

      ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
    21. Jan, ST; Shih, MJ; Venkatachalam, TK; D'Cruz, OJ; Chen, CL; Uckun, FM
      Synthesis of dual function (5R,6R)- and (5S,6S)-5-bromo-6-methoxy-5,6-dihydro-AZT-5 '-(para-bromophenyl methoxyalaninyl phosphate) as novel spermicidal and anti-HIV agents

      ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
    22. Jan, ST; Zhu, Z; Tai, HL; Shih, MJ; Venkatachalam, TK; Uckun, FM
      AZT-5 '-(p-bromophenyl methoxyalaninyl phosphate) as a potent and non-toxic anti-human immunodeficiency virus agent

      ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
    23. Danielsen, EH; Smith, DF; Gee, AD; Venkatachalam, TK; Hansen, SB; Hermansen, F; Gjedde, A; Cumming, P
      Cerebral 6-[F-18]fluoro-L-DOPA (FDOPA) metabolism in pig studied by positron emission tomography

      SYNAPSE
    24. Sudbeck, EA; Jennissen, JD; Venkatachalam, TK; Ucukun, FM
      Inhibitor of HIV-1 reverse transcriptase: N '-(5-bromo-2-pyridyl)-N-[2-(2,5-di-methoxyphenyl)ethyl] thiourea

      ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
    25. Rajamohan, F; Kurinov, IV; Venkatachalam, TK; Uckun, FM
      Deguanylation of human immunodeficiency virus (HIV-1) RNA by recombinant pokeweed antiviral protein

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    26. Rajamohan, F; Venkatachalam, TK; Irvin, JD; Uckun, FM
      Pokeweed antiviral protein isoforms PAP-I, PAP-II, and PAP-III depurinate RNA of human immunodeficiency virus (HIV)-1

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    27. VIG R; MAO C; VENKATACHALAM TK; TUELAHLGREN L; SUDBECK EA; UCKUN FM
      RATIONAL DESIGN AND SYNTHESIS OF PHENETHYL-5-BROMOPYRIDYL THIOUREA DERIVATIVES AS POTENT NONNUCLEOSIDE INHIBITORS OF HIV REVERSE-TRANSCRIPTASE

      Bioorganic & medicinal chemistry
    28. MAO C; VIG R; VENKATACHALAM TK; SUDBECK EA; UCKUN FM
      STRUCTURE-BASED DESIGN OF PIPERIDINYLETHYL)]-N'-[2-(5-BROMOPYRIDYL]-THIOUREA AND IPERAZINYLETHYL)]-N'-[2-(5-BROMOPYRIDYL)]-THIOUREA AS POTENT NONNUCLEOSIDE INHIBITORS OF HIV-1 REVERSE-TRANSCRIPTASE

      Bioorganic & medicinal chemistry letters
    29. VIG R; MAO C; VENKATACHALAM TK; TUELAHLGREN L; SUDBECK EA; UCKUN FM
      LTHIOMETHYL)THIO]-6-(BENZYL)-PYRIMIDIN-4-(1H)-ONES AS POTENT NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITORS OF S-DABO SERIES

      Bioorganic & medicinal chemistry letters
    30. Venkatachalam, TK; Tai, HL; Vig, R; Chen, CL; Jan, ST; Uckun, FM
      Enhancing effects of a mono-bromo substitution at the para position of thephenyl moiety on the metabolism and anti-HIV activity of D4T-phenyl methoxyalaninyl phosphate derivatives

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    31. VIG R; VENKATACHALAM TK; JAN ST; UCKUN FM
      ARYL PHOSPHATE DERIVATIVES OF 3'-DEOXYTHYMIDINE ARE NOT POTENT ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS AGENTS

      Antiviral chemistry & chemotherapy
    32. VIG R; VENKATACHALAM TK; UCKUN FM
      D4T-5'-[P-BROMOPHENYL METHOXYALANINYL PHOSPHATE] AS A POTENT AND NONTOXIC ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS AGENT

      Antiviral chemistry & chemotherapy
    33. Sudbeck, EA; Mao, C; Vig, R; Venkatachalam, TK; Tuel-Ahlgren, L; Uckun, FM
      Structure-based design of novel dihydroalkoxybenzyloxopyrimidine derivatives as potent nonnucleoside inhibitors of the human immunodeficiency virus reverse transcriptase

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    34. DCRUZ OJ; VENKATACHALAM TK; ZHU Z; SHIH MJ; UCKUN FM
      ARYL PHOSPHATE DERIVATIVES OF BROMO-METHOXY-AZIDOTHYMIDINE ARE DUAL-FUNCTION SPERMICIDES WITH POTENT ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS ACTIVITY (VOL 59, PG 503, 1998)

      Biology of reproduction
    35. DCRUZ OJ; VENKATACHALAM TK; ZHU ZH; SHIH MJ; UCKUN FM
      ARYL PHOSPHATE DERIVATIVES OF BROMO-METHOXY-AZIDOTHYMIDINE ARE DUAL-FUNCTION SPERMICIDES WITH POTENT ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS

      Biology of reproduction
    36. BUNCEL E; GORDON RD; VENKATACHALAM TK
      CARBANION MECHANISMS .20. IS THERE CHARGE DELOCALIZATION IN PHENYL-SUBSTITUTED GROUP-4 ANIONS - EVIDENCE FROM ELECTRONIC ABSORPTION-SPECTROSCOPY

      Journal of organometallic chemistry
    37. MZENGEZA S; VENKATACHALAM TK; DIKSIC M
      ASYMMETRIC RADIOSYNTHESIS OF ALPHA-[C-11]METHYL-L-TRYPTOPHAN FOR PET STUDIES

      Nuclear medicine and biology
    38. BUNCEL E; VENKATACHALAM TK
      GENERATION OF GERMYL, STANNYL, AND PLUMBYL ANIONS THROUGH NUCLEOPHILIC CLEAVAGE OF DIGERMANES, DISTANNANES, AND DIPLUMBANES

      Heteroatom chemistry
    39. CUMMING P; VENKATACHALAM TK; RAJAGOPAL S; DIKSIC M; GJEDDE A
      BRAIN UPTAKE OF ALPHA-[C-14]METHYL-PARA-TYROSINE IN THE RAT

      Synapse
    40. LIU MTH; ROMASHIN YN; VENKATACHALAM TK
      PHOTOLYSIS OF 3-CHLORO-3-ARYLDIAZIRINES IN THE PRESENCE OF AMINES ANDALLYL ALCOHOL

      Canadian journal of chemistry
    41. MZENGEZA S; VENKATACHALAM TK; RAJAGOPAL S; DIKSIC M
      SYNTHESIS OF ENANTIOMERICALLY PURE ALPHA-[C-14]METHYL-L-TRYPTOPHAN

      Applied radiation and isotopes
    42. VENKATACHALAM TK; MZENGEZA S; DIKSIC M
      SYNTHESIS OF ALPHA-[C-14]METHYL AND A-[H-3]METHYL-L-TRYPTOPHAN

      Journal of labelled compounds & radiopharmaceuticals
    43. RHODES CJ; AGIRBAS H; SHINE HJ; HOQUE AKMM; VENKATACHALAM TK
      SUBSTITUENT EFFECTS IN DIPHENYLMERCURY RADICAL CATIONS - A VERY CLEARDISTINCTION BETWEEN SIGMA-STATE AND PI-STATE

      Perkin transactions. 2
    44. VENKATACHALAM TK; MZENGEZA S; DIKSIC M
      AN IMPROVED SYNTHESIS OF 1-(T-BUTYLOXYCARBONYL)-3-(BROMOMETHYL)INDOLE

      Organic preparations and procedures international


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Documento generato il 19/10/20 alle ore 23:51:45