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    1. Caplan, JF; Sutherland, A; Vederas, JC
      The first stereospecific synthesis of L-tetrahydrodipicolinic acid; a key intermediate of diaminopimelate metabolism

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    2. Auclair, K; Kennedy, J; Hutchinson, CR; Vederas, JC
      Conversion of cyclic nonaketides to lovastatin and compactin by a lovC deficient mutant of Aspergillus terreus

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    3. Caplan, JF; Zheng, RJ; Blanchard, JS; Vederas, JC
      Vinylogous amide analogues of diaminopimelic acid (DAP) as inhibitors of enzymes involved in bacterial lysine biosynthesis

      ORGANIC LETTERS
    4. Franz, CMAP; van Belkum, MJ; Worobo, RW; Vederas, JC; Stiles, ME
      Characterization of the genetic locus responsible for production and immunity of carnobacteriocin A: the immunity gene confers cross-protection to enterocin B

      MICROBIOLOGY-UK
    5. Cox, RJ; Sutherland, A; Vederas, JC
      Bacterial diaminopimelate metabolism as a target for antibiotic design

      BIOORGANIC & MEDICINAL CHEMISTRY
    6. Cirilli, M; Scapin, G; Sutherland, A; Vederas, JC; Blanchard, JS
      The three-dimensional structure of the ternary complex of Corynebacterium glutamicum diaminopimelate dehydrogenase-NADPH-L-2-amino-6-methylene-pimelate

      PROTEIN SCIENCE
    7. Yan, LZ; Gibbs, AC; Stiles, ME; Wishart, DS; Vederas, JC
      Analogues of bacteriocins: Antimicrobial specificity and interactions of leucocin A with its enantiomer, carnobacteriocin B2, and truncated derivatives

      JOURNAL OF MEDICINAL CHEMISTRY
    8. DeBlassio, JL; deLong, MA; Glufke, U; Kulathila, R; Merkler, KA; Vederas, JC; Merkler, DJ
      Amidation of salicyluric acid and gentisuric acid: A possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    9. King, L; Barnes, S; Glufke, U; Henz, ME; Kirk, M; Merkler, KA; Vederas, JC; Wilcox, BJ; Merkler, DJ
      The enzymatic formation of novel bile acid primary amides

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    10. Auclair, K; Sutherland, A; Kennedy, J; Witter, DJ; Van den Heever, JP; Hutchinson, CR; Vederas, JC
      Lovastatin nonaketide synthase catalyzes an intramolecular Diels-Alder reaction of a substrate analogue

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    11. Koo, CW; Sutherland, A; Vederas, JC; Blanchard, JS
      Identification of active site cysteine residues that function as general bases: Diaminopimelate epimerase

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    12. Lall, MS; Karvellas, C; Vederas, JC
      beta-lactones as a new class of cysteine proteinase inhibitors: Inhibitionof hepatitis a virus 3C proteinase by N-Cbz-serine beta-lactone

      ORGANIC LETTERS
    13. Sutherland, A; Caplan, JF; Vederas, JC
      Unsaturated alpha-aminopimelic acids as potent inhibitors of meso-diaminopimelic acid (DAP) D-dehydrogenase

      CHEMICAL COMMUNICATIONS
    14. Sutherland, A; Vederas, JC
      The first isolation of an alkoxy-N,N-dialkylaminodifluorosulfane from the reaction of an alcohol and DAST: an efficient synthesis of (2S,3R,6S)-3-fluoro-2,6-diaminopimelic acid

      CHEMICAL COMMUNICATIONS
    15. Huang, YT; Malcolm, BA; Vederas, JC
      Synthesis and testing of azaglutamine derivatives as inhibitors of hepatitis A virus (HAV) 3C proteinase

      BIOORGANIC & MEDICINAL CHEMISTRY
    16. Franz, CMAP; Worobo, RW; Quadri, LEN; Schillinger, U; Holzapfel, WH; Vederas, JC; Stiles, ME
      Atypical genetic locus associated with constitutive production of enterocin B by Enterococcus faecium BFE 900

      APPLIED AND ENVIRONMENTAL MICROBIOLOGY
    17. Bergmann, EM; Cherney, MM; Mckendrick, J; Frormann, S; Luo, C; Malcolm, BA; Vederas, JC; James, MNG
      Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis a virus (HAV) and implications for the polyprotein processing in HAV

      VIROLOGY
    18. Kennedy, J; Auclair, K; Kendrew, SG; Park, C; Vederas, JC; Hutchinson, CR
      Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis

      SCIENCE
    19. Hill, RD; Vederas, JC
      Azodicarboxamides: A new class of cysteine proteinase inhibitor for hepatitis A virus and human rhinovirus 3C enzymes

      JOURNAL OF ORGANIC CHEMISTRY
    20. Zheng, GL; Yan, LZ; Vederas, JC; Zuber, P
      Genes of the sbo-alb locus of Bacillus subtilis are required for production of the antilisterial bacteriocin subtilosin

      JOURNAL OF BACTERIOLOGY
    21. Wang, YJ; Henz, ME; Gallagher, NLF; Chai, SY; Gibbs, AC; Yan, LZ; Stiles, ME; Wishart, DS; Vederas, JC
      Solution structure of carnobacteriocin B2 and implications for structure-activity relationships among type IIa bacteriocins from lactic acid bacteria

      BIOCHEMISTRY
    22. Wilcox, BJ; Ritenour-Rodgers, KJ; Asser, AS; Baumgart, LE; Baumgart, MA; Boger, DL; DeBlassio, JL; deLong, MA; Glufke, U; Henz, ME; King, L; Merkler, KA; Patterson, JE; Robleski, JJ; Vederas, JC; Merkler, DJ
      N-acylglycine amidation: Implications for the biosynthesis of fatty acid primary amides

      BIOCHEMISTRY
    23. Merkler, DJ; Glufke, U; Ritenour-Rodgers, KJ; Baumgart, LE; DeBlassio, JL; Merkler, KA; Vederas, JC
      Formation of nicotinamide from nicotinuric acid by peptidylglycine alpha-amidating monooxygenase (PAM): A possible alternative route from nicotinic acid (niacin) to NADP in mammals

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    24. MCKENDRICK JE; FRORMANN S; LUO C; SEMCHUCK P; VEDERAS JC; MALCOLM BA
      RAPID MASS-SPECTROMETRIC DETERMINATION OF PREFERRED IRREVERSIBLE PROTEINASE-INHIBITORS IN COMBINATORIAL LIBRARIES

      International journal of mass spectrometry and ion processes
    25. McCormick, JK; Poon, A; Sailer, M; Gao, Y; Roy, KL; McMullen, LM; Vederas, JC; Stiles, ME; Van Belkum, MJ
      Genetic characterization and heterologous expression of brochocin-C, an antibotulinal, two-peptide bacteriocin produced by Brochothrix campestris ATCC 43754

      APPLIED AND ENVIRONMENTAL MICROBIOLOGY
    26. Liu, YQ; Li, Z; Vederas, JC
      Biosynthetic incorporation of advanced precursors into dehydrocurvularin, a polyketide phytotoxin from Alternaria cinerariae

      TETRAHEDRON
    27. GAO Y; LANEBELL P; VEDERAS JC
      STEREOSELECTIVE SYNTHESIS OF MESO-2,6-DIAMINOPIMELIC ACID AND ITS SELECTIVELY PROTECTED DERIVATIVES

      Journal of organic chemistry
    28. HARRIS JM; LIU YQ; CHAI SY; ANDREWS MD; VEDERAS JC
      MODIFICATION OF THE SWERN OXIDATION - USE OF A SOLUBLE POLYMER-BOUND,RECYCLABLE, AND ODORLESS SULFOXIDE

      Journal of organic chemistry
    29. SCAPIN G; CIRILLI M; REDDY SG; GAO Y; VEDERAS JC; BLANCHARD JS
      SUBSTRATE AND INHIBITOR BINDING-SITES IN CORYNEBACTERIUM-GLUTAMICUM DIAMINOPIMELATE DEHYDROGENASE

      Biochemistry
    30. MORRIS TS; FRORMANN S; SHECHOSKY S; LOWE C; LALL MS; GAUSSMULLER V; PURCELL RH; EMERSON SU; VEDERAS JC; MALCOLM BA
      IN-VITRO AND EX-VIVO INHIBITION OF HEPATITIS-A VIRUS 3C PROTEINASE BYA PEPTIDYL MONOFLUOROMETHYL KETONE

      Bioorganic & medicinal chemistry
    31. JAMES MNG; BERGMANN EM; MOSIMANN SC; CHERNAIA MM; MALCOLM BA; FRORMANN S; VEDERAS JC; PLOTCH SJ
      THE STRUCTURAL BIOLOGY OF PICORNAVIRAL PROCESSING PROTEINASES

      The FASEB journal
    32. ANDREWS MD; OCALLAGHAN KA; VEDERAS JC
      SYNTHESIS OF TRIPEPTIDE INHIBITORS OF PEPTIDYLGLYCINE ALPHA-AMIDATINGMONOOXYGENASE (PAM) CONTAINING D-STYRYLGLYCINE AND L-STYRYLGLYCINE

      Tetrahedron
    33. QUADRI LEN; YAN LZ; STILES ME; VEDERAS JC
      EFFECT OF AMINO-ACID SUBSTITUTIONS ON THE ACTIVITY OF CARNOBACTERIOCIN B2 - OVERPRODUCTION OF THE ANTIMICROBIAL PEPTIDE, ITS ENGINEERED VARIANTS, AND ITS PRECURSOR IN ESCHERICHIA-COLI

      The Journal of biological chemistry
    34. QUADRI LEN; KLEEREBEZEM M; KUIPERS OP; DEVOS WM; ROY KL; VEDERAS JC; STILES ME
      CHARACTERIZATION OF A LOCUS FROM CARNOBACTERIUM-PISCICOLA LV17B INVOLVED IN BACTERIOCIN PRODUCTION AND IMMUNITY - EVIDENCE FOR GLOBAL INDUCER-MEDIATED TRANSCRIPTIONAL REGULATION

      Journal of bacteriology
    35. GALLAGHER NLF; SAILER M; NIEMCZURA WP; NAKASHIMA TT; STILES ME; VEDERAS JC
      3-DIMENSIONAL STRUCTURE OF LEUCOCIN-A IN TRIFLUOROETHANOL AND DODECYLPHOPHOCHOLINE MICELLES - SPATIAL LOCATION OF RESIDUES CRITICAL FOR BIOLOGICAL-ACTIVITY IN TYPE IIA BACTERIOCINS FROM LACTIC-ACID BACTERIA

      Biochemistry
    36. HARRIS JM; MCDONALD R; VEDERAS JC
      SYNTHESIS OF A CHIRAL AZODICARBOXAMIDE CONTAINING ABRIDGING BINAPHTHYL MOIETY - ELECTROPHILIC AMINATION REACTIONS OF ACHIRAL ESTER ENOLATES

      Journal of the Chemical Society. Perkin transactions. I
    37. WAGSCHAL K; YOSHIZAWA Y; WITTER DJ; LIU YQ; VEDERAS JC
      BIOSYNTHESIS OF ML-236C AND THE HYPOCHOLESTEROLEMIC AGENTS COMPACTIN BY PENICILLIUM-AURANTIOGRISEUM AND LOVASTATIN BY ASPERGILLUS-TERREUS -DETERMINATION OF THE ORIGIN OF CARBON, HYDROGEN AND OXYGEN-ATOMS BY C-13 NMR SPECTROMETRY AND OBSERVATION OF UNUSUAL LABELING OF ACETATE-DERIVED OXYGENS BY O-18(2)

      Journal of the Chemical Society. Perkin transactions. I
    38. WITTER DJ; VEDERAS JC
      PUTATIVE DIELS-ALDER-CATALYZED CYCLIZATION DURING THE BIOSYNTHESIS OFLOVASTATIN

      Journal of organic chemistry
    39. LIU YQ; VEDERAS JC
      MODIFICATION OF THE SWERN OXIDATION - USE OF STOICHIOMETRIC AMOUNTS OF AN EASILY SEPARABLE, RECYCLABLE, AND ODORLESS SULFOXIDE THAT CAN BE POLYMER-BOUND

      Journal of organic chemistry
    40. RATEMI ES; DOLENCE JM; POULTER CD; VEDERAS JC
      SYNTHESIS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE INHIBITORS - RAPID ACCESS TO CHAETOMELLIC ACID-A AND ITS ANALOGS

      Journal of organic chemistry
    41. AUGER G; VANHEIJENOORT J; VEDERAS JC; BLANOT D
      EFFECT OF ANALOGS OF DIAMINOPIMELIC ACID ON THE MESO-DIAMINOPIMELATE-ADDING ENZYME FROM ESCHERICHIA-COLI

      FEBS letters
    42. COX RJ; SHERWIN WA; LAM LKP; VEDERAS JC
      SYNTHESIS AND EVALUATION OF NOVEL SUBSTRATES AND INHIBITORS OF N-SUCCINYL-LL-DIAMINOPIMELATE AMINOTRANSFERASE (DAP-AT) FROM ESCHERICHIA-COLI

      Journal of the American Chemical Society
    43. HARRIS JM; BOLESSA EA; MENDONCA AJ; FENG SC; VEDERAS JC
      SYNTHESIS OF CHIRAL DIAZANEDICARBOXYLATE AND DIAZENEDICARBOXYLATE ESTERS - ELECTROPHILIC AMINATION REACTIONS OF ACHIRAL ESTER AND AMIDE ENOLATES

      Journal of the Chemical Society. Perkin transactions. I
    44. HARRIS JM; BOLESSA EA; VEDERAS JC
      SYNTHESIS OF MACROCYCLIC DIAZANEDICARBOXYLATE AND DIAZENEDICARBOXYLATE ESTERS CONTAINING A STEROID SKELETON - AN UNUSUAL OXIDATION OF BROMIDE TO BROMINE BY A STRAINED DIAZENEDICARBOXYLATE ESTER - X-RAY MOLECULAR-STRUCTURE OF -(3-HYDROXYPROPYL)-24-NOR-5-BETA-CHOLAN-7-ALPHA-OL DIAZANE-1,2-DICARBOXYLATE CYCLIC DIESTER

      Journal of the Chemical Society. Perkin transactions. I
    45. LOWE C; VEDERAS JC
      NATURALLY-OCCURRING BETA-LACTONES - OCCURRENCE, SYNTHESES AND PROPERTIES - A REVIEW

      Organic preparations and procedures international
    46. QUADRI LEN; SAILER M; TEREBIZNIK MR; ROY KL; VEDERAS JC; STILES ME
      CHARACTERIZATION OF THE PROTEIN CONFERRING IMMUNITY TO THE ANTIMICROBIAL PEPTIDE CARNOBACTERIOCIN B2 AND EXPRESSION OF CARNOBACTERIOCINS B2AND BM1

      Journal of bacteriology
    47. WOROBO RW; VANBELKUM MJ; SAILER M; ROY KL; VEDERAS JC; STILES ME
      A SIGNAL PEPTIDE SECRETION-DEPENDENT BACTERIOCIN FROM CARNOBACTERIUM DIVERGENS

      Journal of bacteriology
    48. MALCOLM BA; LOWE C; SHECHOSKY S; MCKAY RT; YANG CC; SHAH VJ; SIMON RJ; VEDERAS JC; SANTI DV
      PEPTIDE ALDEHYDE INHIBITORS OF HEPATITIS-A VIRUS 3C PROTEINASE

      Biochemistry
    49. WOROBO RW; HENKEL T; SAILER M; ROY KL; VEDERAS JC; STILES ME
      CHARACTERISTICS AND GENETIC DETERMINANT OF A HYDROPHOBIC PEPTIDE BACTERIOCIN, CARNOBACTERIOCIN-A, PRODUCED BY CARNOBACTERIUM-PISCICOLA-LV17A

      Microbiology
    50. ZABRISKIE TM; KLINGE M; SZYMANSKI CM; CHENG HM; VEDERAS JC
      PEPTIDE AMIDATION IN AN INVERTEBRATE - PURIFICATION, CHARACTERIZATIONAND INHIBITION OF PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE FROM THE HEADS OF HONEYBEES (APIS-MELLIFERA)

      Archives of insect biochemistry and physiology
    51. RATEMI ES; VEDERAS JC
      REACTION OF TRIMETHYLSILYLAMINES WITH N-CBZ-L-SERINE-BETA-LACTONE - ACONVENIENT ROUTE TO OPTICALLY PURE BETA-AMINO-L-ALANINE DERIVATIVES

      Tetrahedron letters
    52. KLINGE M; CHENG HM; ZABRISKIE TM; VEDERAS JC
      IRREVERSIBLE INHIBITION OF MAMMALIAN AND INSECT PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASES (PHMS), PEPTIDE AMIDATING ENZYMES, BY N-FORMYL AMIDES

      Journal of the Chemical Society, Chemical Communications
    53. SONG YH; NIEDERER D; LANEBELL PM; LAM LKP; CRAWLEY S; PALCIC MM; PICKARD MA; PRUESS DL; VEDERAS JC
      STEREOSPECIFIC SYNTHESIS OF PHOSPHONATE ANALOGS OF DIAMINOPIMELIC ACID (DAP), THEIR INTERACTION WITH DAP ENZYMES, ND ANTIBACTERIAL ACTIVITYOF PEPTIDE DERIVATIVES

      Journal of organic chemistry
    54. PU YL; LOWE C; SAILER M; VEDERAS JC
      SYNTHESIS, STABILITY, AND ANTIMICROBIAL ACTIVITY OF (-OBAFLUORIN AND RELATED BETA-LACTONE ANTIBIOTICS())

      Journal of organic chemistry
    55. QUADRI LEN; SAILER M; ROY KL; VEDERAS JC; STILES ME
      CHEMICAL AND GENETIC-CHARACTERIZATION OF BACTERIOCINS PRODUCED BY CARNOBACTERIUM-PISCICOLA LV17B

      The Journal of biological chemistry
    56. YOSHIZAWA Y; WITTER DJ; LIU YQ; VEDERAS JC
      REVISION OF THE BIOSYNTHETIC ORIGIN OF OXYGENS IN MEVINOLIN (LOVASTATIN), A HYPOCHOLESTEROLEMIC DRUG FROM ASPERGILLUS-TERREUS MF-4845

      Journal of the American Chemical Society
    57. ABBOTT SD; LANEBELL P; SIDHU KPS; VEDERAS JC
      SYNTHESIS AND TESTING OF HETEROCYCLIC-ANALOGS OF DIAMINOPIMELIC ACID (DAP) AS INHIBITORS OF DAP DEHYDROGENASE AND DAP EPIMERASE

      Journal of the American Chemical Society
    58. NIEDERER DA; KAPRON JT; VEDERAS JC
      AMINATION WITH N-BENZYLOXYCARBONYL-3-PHENYLOXAZIRIDINE AS A ROUTE TO SENSITIVE CHIRAL ALPHA-HYDRAZINO ACIDS - SYNTHESIS OF L-HYDRAZINO SERINE

      Tetrahedron letters
    59. QIAO L; VEDERAS JC
      SYNTHESIS OF A C-PHOSPHONATE DISACCHARIDE AS A POTENTIAL INHIBITOR OFPEPTIDOGLYCAN POLYMERIZATION BY TRANSGLYCOSYLASE

      Journal of organic chemistry


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Documento generato il 02/06/20 alle ore 22:59:28