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La ricerca find articoli where authors phrase all words ' SUTCLIFFE MJ' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 74 riferimenti
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    1. Raven, EL; Celik, A; Cullis, PM; Sangar, R; Sutcliffe, MJ
      Engineering the active site of ascorbate peroxidase

      BIOCHEMICAL SOCIETY TRANSACTIONS
    2. Sutcliffe, MJ; Mueller, OT; Kousseff, BG; Dumont, DP; McFarland, JA; Mawani, F; Conforto, D; Ranells, JD
      Three cell line mosaicism involving structural and numerical abnormalitiesof chromosome 18 in a 3.5-year-old girl: 47,XX,+18/47,XX,+del(18)(q22)/46,XX

      AMERICAN JOURNAL OF MEDICAL GENETICS
    3. So, I; Ashmole, I; Davies, NW; Sutcliffe, MJ; Stanfield, PR
      The K+ channel signature sequence of murine Kir2.l: mutations that affect microscopic gating but not ionic selectivity

      JOURNAL OF PHYSIOLOGY-LONDON
    4. Basran, J; Patel, S; Sutcliffe, MJ; Scrutton, NS
      Importance of barrier shape in enzyme-catalyzed reactions - Vibrationally assisted hydrogen tunneling in tryptophan tryptophylquinone-dependent aminedehydrogenases

      JOURNAL OF BIOLOGICAL CHEMISTRY
    5. Basran, J; Sutcliffe, MJ; Scrutton, NS
      Optimizing the Michaelis complex of trimethylamine dehydrogenase - Identification of interactions that perturb the ionization of substrate and facilitate catalysis with trimethylamine base

      JOURNAL OF BIOLOGICAL CHEMISTRY
    6. Chohan, KK; Jones, M; Grossmann, JG; Frerman, FE; Scrutton, NS; Sutcliffe, MJ
      Protein dynamics enhance electronic coupling in electron transfer complexes

      JOURNAL OF BIOLOGICAL CHEMISTRY
    7. Basran, J; Sutcliffe, MJ; Scrutton, NS
      Deuterium isotope effects during carbon-hydrogen bond cleavage by trimethylamine dehydrogenase - Implications for mechanism and vibrationally assisted hydrogen tunneling in wild-type and mutant enzymes

      JOURNAL OF BIOLOGICAL CHEMISTRY
    8. Talfournier, F; Munro, AW; Basran, J; Sutcliffe, MJ; Daff, S; Chapman, SK; Scrutton, NS
      alpha Arg-237 in Methylophilus methylotrophus (sp W3A1) electron-transferring flavoprotein affords similar to 200-millivolt stabilization of the FAD anionic semiquinone and a kinetic block on full reduction to the dihydroquinone

      JOURNAL OF BIOLOGICAL CHEMISTRY
    9. Celik, A; Cullis, PM; Sutcliffe, MJ; Sangar, R; Raven, EL
      Engineering the active site of ascorbate peroxidase

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    10. Faulder, PF; Tresadern, G; Chohan, KK; Scrutton, NS; Sutcliffe, MJ; Hillier, IH; Burton, NA
      QM/MM studies show substantial tunneling for the hydrogen-transfer reaction in methylamine dehydrogenase

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    11. Chohan, KK; Wo, ZG; Oswald, RE; Sutcliffe, MJ
      Structural insights into NMDA ionotropic glutamate receptors via molecularmodelling

      JOURNAL OF MOLECULAR MODELING
    12. Sutcliffe, MJ; Scrutton, MS
      Enzymology takes a quantum leap forward

      PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
    13. Sutcliffe, MJ; Scrutton, NS
      Enzyme catalysis: over-the-barrier or through-the-barrier?

      TRENDS IN BIOCHEMICAL SCIENCES
    14. Thompson, GA; Leyland, ML; Ashmole, I; Sutcliffe, MJ; Stanfield, PR
      Residues beyond the selectivity filter of the K+ channel Kir2.1 regulate permeation and block by external Rb+ and Cs+

      JOURNAL OF PHYSIOLOGY-LONDON
    15. Jones, M; Basran, J; Sutcliffe, MJ; Grossmann, JG; Scrutton, NS
      X-ray scattering studies of Methylophilus methylotrophus (sp W(3)A(1)) electron-transferring flavoprotein - Evidence for multiple conformational states and an induced fit mechanism for assembly with trimethylamine dehydrogenase

      JOURNAL OF BIOLOGICAL CHEMISTRY
    16. Harris, RJ; Meskys, R; Sutcliffe, MJ; Scrutton, NS
      Kinetic studies of the mechanism of carbon-hydrogen bond breakage by the heterotetrameric sarcosine oxidase of Arthrobacter sp 1-IN

      BIOCHEMISTRY
    17. Basran, J; Chohan, KK; Sutcliffe, MJ; Scrutton, NS
      Differential coupling through Val-344 and Tyr-442 of trimethylamine dehydrogenase in electron transfer reactions with ferricenium ions and electron transferring flavoprotein

      BIOCHEMISTRY
    18. Trickey, P; Basran, J; Lian, LY; Chen, ZW; Barton, JD; Sutcliffe, MJ; Scrutton, NS; Mathews, FS
      Structural and biochemical characterization of recombinant wild type and aC30A mutant of trimethylamine dehydrogenase from Methylphilus methylotrophus (sp W(3)A(1))

      BIOCHEMISTRY
    19. Fowler, SM; Riley, RJ; Pritchard, MP; Sutcliffe, MJ; Friedberg, T; Wolf, CR
      Amino acid 305 determines catalytic center accessibility in CYP3A4

      BIOCHEMISTRY
    20. Gizachew, D; Guo, W; Chohan, KK; Sutcliffe, MJ; Oswald, RE
      Structure of the complex of Cdc42Hs with a peptide derived from p-21 activated kinase

      BIOCHEMISTRY
    21. Scrutton, NS; Basran, J; Wilson, EK; Chohan, KK; Jang, MH; Sutcliffe, MJ; Hille, R
      Electron transfer in trimethylamine dehydrogenase and electron-transferring flavoprotein

      BIOCHEMICAL SOCIETY TRANSACTIONS
    22. Basran, J; Sutcliffe, MJ; Hille, R; Scrutton, NS
      Reductive half-reaction of the H172Q mutant of trimethylamine dehydrogenase: evidence against a carbanion mechanism and assignment of kinetically influential ionizations in the enzyme-substrate complex

      BIOCHEMICAL JOURNAL
    23. Leyland, ML; Dart, C; Spencer, PJ; Sutcliffe, MJ; Stanfield, PR
      The possible role of a disulphide bond in forming functional Kir2.1 potassium channels

      PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
    24. Wo, ZG; Chohan, KK; Chen, HY; Sutcliffe, MJ; Oswald, RE
      Cysteine mutagenesis and homology modeling of the ligand-binding site of akainate-binding protein

      JOURNAL OF BIOLOGICAL CHEMISTRY
    25. Basran, J; Jang, MH; Sutcliffe, MJ; Hille, R; Scrutton, NS
      The role of Tyr-169 of trimethylamine dehydrogenase in substrate oxidationand magnetic interaction between FMN cofactor and the 4Fe/4S center

      JOURNAL OF BIOLOGICAL CHEMISTRY
    26. Scrutton, NS; Basran, J; Sutcliffe, MJ
      New insights into enzyme catalysis - Ground state tunnelling driven by protein dynamics

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    27. Basran, J; Sutcliffe, MJ; Scrutton, NS
      Enzymatic H-transfer requires vibration-driven extreme tunneling

      BIOCHEMISTRY
    28. CULLIS PM; MERSONDAVIES L; SUTCLIFFE MJ; WEAVER R
      DNA ALKYLATION SITES OF NITROGEN MUSTARDS CONJUGATED TO POLYAMINES AND THEIR IMPLICATIONS FOR POLYAMINE-DNA INTERACTIONS

      Chemical communications
    29. Sutcliffe, MJ; Smeeton, AH; Wo, ZG; Oswald, RE
      Three-dimensional models of glutamate receptors

      Faraday discussions
    30. ROSSBACH HC; SUTCLIFFE MJ; CHAMIZO W; HAAG MM; GRANA NH; WASHINGTON KR; BARBOSA JL
      PRE-B ACUTE LYMPHOBLASTIC-LEUKEMIA IN A 3-YEAR-OLD BOY WITH PRE-ACUTEMYELOGENOUS LEUKEMIA MYELODYSPLASTIC SYNDROME - CYTOGENETIC EVIDENCE OF COMMON EARLY PROGENITOR-CELL ONTOGENY

      Journal of pediatric hematology/oncology
    31. Hartsfield, JK; Sutcliffe, MJ; Everett, ET; Hassett, C; Omiecinski, CJ; Saari, JA
      Assignment of microsomal epoxide hydrolase (EPHX1) to human chromosome 1q42.1 by in situ hybridization

      CYTOGENETICS AND CELL GENETICS
    32. SUTCLIFFE MJ; SMEETON AH; WO ZG; OSWALD RE
      3-DIMENSIONAL MODELS OF GLUTAMATE RECEPTORS

      Biochemical Society transactions
    33. ERTUGHRUL OWD; ERRINGTON N; RAZA S; SUTCLIFFE MJ; ROWE AJ; SCRUTTON NS
      PROBING THE STABILIZING ROLE OF C-TERMINAL RESIDUES IN TRIMETHYLAMINEDEHYDROGENASE

      Protein engineering (Print)
    34. SMITH G; MODI S; PILLAI I; LIAN LY; SUTCLIFFE MJ; PRITCHARD MP; FRIEDBERG T; ROBERTS GCK; WOLF CR
      DETERMINANTS OF THE SUBSTRATE-SPECIFICITY OF HUMAN CYTOCHROME-P-450 CYP2D6 - DESIGN AND CONSTRUCTION OF A MUTANT WITH TESTOSTERONE HYDROXYLASE-ACTIVITY

      Biochemical journal
    35. DART C; LEYLAND ML; BARRETTJOLLEY R; SHELTON PA; SPENCER PJ; CONLEY EC; SUTCLIFFE MJ; STANFIELD PR
      THE DEPENDENCE OF AG+ BLOCK OF A POTASSIUM CHANNEL, MURINE KIR2.1, ONA CYSTEINE RESIDUE IN THE SELECTIVITY FILTER

      Journal of physiology
    36. DART C; LEYLAND ML; SPENCER PJ; STANFIELD PR; SUTCLIFFE MJ
      THE SELECTIVITY FILTER OF A POTASSIUM CHANNEL, MURINE KIR2.1, INVESTIGATED USING SCANNING CYSTEINE MUTAGENESIS

      Journal of physiology
    37. ROBERTS GCK; MODI S; SUTCLIFFE MJ; LIAN LY; PRIMROSE WU; WOLF CR
      THE USE OF NMR METHODS TO STUDY SUBSTRATE-BINDING TO CYTOCHROMES P450

      British Journal of Pharmacology
    38. GUO W; SUTCLIFFE MJ; CERIONE RA; OSWALD RE
      DEFINITION OF THE BINDING SURFACE ON CDC42HS FOR P21-ACTIVATED KINASE

      Biophysical journal
    39. SUTCLIFFE MJ; SMEETON AH; WO ZG; OSWALD RE
      3-DIMENSIONAL MODELS OF GLUTAMATE RECEPTORS

      Biophysical journal
    40. GUO W; SUTCLIFFE MJ; CERIONE RA; OSWALD RE
      IDENTIFICATION OF THE BINDING SURFACE ON CDC42HS FOR P21-ACTIVATED KINASE

      Biochemistry (Easton)
    41. KELLEY LA; SUTCLIFFE MJ
      OLDERADO - ONLINE DATABASE OF ENSEMBLE REPRESENTATIVES AND DOMAINS

      Protein science
    42. MODI S; PAINE MJ; OLIVER CF; SMITH G; SUTCLIFFE MJ; GILHAM DE; SHAW ANJ; LIAN LY; PRIMROSE WU; WOLF CR; ROBERTS GCK
      ACTIVE-SITE MODELS OF HUMAN CYTOCHROME P450S BASED ON NMR RELAXATION MEASUREMENTS

      The FASEB journal
    43. ROBERTS GCK; SUTCLIFFE MJ; MODI S; LIAN LY; PRIMROSE WU; WOLF CR
      CONSTRUCTION OF MODELS OF P450-SUBSTRATE COMPLEXES BY A COMBINATION OF NMR AND HOMOLOGY MODELING

      The FASEB journal
    44. ROBERTS GCK; MODI S; GILHAM DE; SUTCLIFFE MJ; LIAN LY; PRIMROSE WU; WOLF CR
      ALLOSTERIC EFFECTS OF CYTOCHROME-P450 REDUCTASE ON CYTOCHROME-P450 2D6

      The FASEB journal
    45. KELLEY LA; GARDNER SP; SUTCLIFFE MJ
      AN AUTOMATED APPROACH FOR DEFINING CORE ATOMS AND DOMAINS IN AN ENSEMBLE OF NMR-DERIVED PROTEIN STRUCTURES

      Protein engineering
    46. DART C; LEYLAND ML; SPENCER PJ; CONLEY EC; STANFIELD PR; SUTCLIFFE MJ
      POSSIBLE TOPOLOGY OF THE H5 REGION OF AN INWARD RECTIFIER K+ CHANNEL,MURINE IRK1

      Journal of physiology
    47. HILL AP; MODI S; SUTCLIFFE MJ; TURNER DD; GILFOYLE DJ; SMITH AT; TAM BM; LLOYD E
      CHEMICAL, SPECTROSCOPIC AND STRUCTURAL INVESTIGATION OF THE SUBSTRATE-BINDING SITE IN ASCORBATE PEROXIDASE

      European journal of biochemistry
    48. OLIVER CF; MODI S; SUTCLIFFE MJ; PRIMROSE WU; LIAN LY; ROBERTS GCK
      A SINGLE MUTATION IN CYTOCHROME-P450 BM3 CHANGES SUBSTRATE ORIENTATION IN A CATALYTIC INTERMEDIATE AND THE REGIOSPECIFICITY OF HYDROXYLATION

      Biochemistry
    49. FELTHAM JL; DOTSCH V; RAZA S; MANOR D; CERIONE RA; SUTCLIFFE MJ; WAGNER G; OSWALD RE
      DEFINITION OF THE SWITCH SURFACE IN THE SOLUTION STRUCTURE OF CDC42HS

      Biochemistry
    50. MODI S; GILHAM DE; SUTCLIFFE MJ; LIAN LY; PRIMROSE WU; WOLF CR; ROBERTS GCK
      1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE AS A SUBSTRATE OF CYTOCHROME-P450 2D6 - ALLOSTERIC EFFECTS OF NADPH-CYTOCHROME P450 REDUCTASE

      Biochemistry
    51. WILSON EK; HUANG LX; SUTCLIFFE MJ; MATHEWS FS; HILLE R; SCRUTTON NS
      AN EXPOSED TYROSINE ON THE SURFACE OF TRIMETHYLAMINE DEHYDROGENASE FACILITATES ELECTRON-TRANSFER TO ELECTRON TRANSFERRING FLAVOPROTEIN - KINETICS OF TRANSFER IN WILD-TYPE AND MUTANT COMPLEXES

      Biochemistry
    52. SUTCLIFFE MJ; SAARI JA; NELSON RP; KLEMPERER M; WEIL N; DUMONT DP; HINDSFREY K; TOS A
      DISCREPANT DIRECT VS CULTURED LYMPHOCYTE DONOR ENGRAFTMENT RESULTS POST BONE-MARROW TRANSPLANT USING THE CEP X Y FISH PROBE IN IMMUNODEFICIENCY DISORDERS/

      American journal of human genetics
    53. ATKINSON RS; BARKER E; SUTCLIFFE MJ
      N-ACETYL-N-ACYL-3-AMINOQUINAZOLINONES AS CHEMOSELECTIVE ACETYLATING AGENTS

      Chemical communications
    54. MODI S; SUTCLIFFE MJ; PRIMROSE WU; LIAN LY; ROBERTS GCK
      THE CATALYTIC MECHANISM OF CYTOCHROME-P450 BM3 INVOLVES A 6-ANGSTROM MOVEMENT OF THE BOUND SUBSTRATE ON REDUCTION

      Nature structural biology
    55. KELLEY LA; GARDNER SP; SUTCLIFFE MJ
      AN AUTOMATED APPROACH FOR CLUSTERING AN ENSEMBLE OF NMR-DERIVED PROTEIN STRUCTURES INTO CONFORMATIONALLY RELATED SUBFAMILIES

      Protein engineering
    56. ROMIE SS; HARTSFIELD JK; SUTCLIFFE MJ; DUMONT DP; KOUSSEFF BG
      MONOSOMY 6Q1 - SYNDROME DELINEATION

      American journal of medical genetics
    57. ROSSBACH HC; SUTCLIFFE MJ; HAAG MM; GRANA NH; ROSSI AR; BARBOSA JL
      FANCONI-ANEMIA IN BROTHERS INITIALLY DIAGNOSED WITH VACTERL ASSOCIATION WITH HYDROCEPHALUS, AND SUBSEQUENTLY WITH BALLER-GEROLD SYNDROME

      American journal of medical genetics
    58. CABRAL JHM; PETOSA C; SUTCLIFFE MJ; RAZA S; BYRON O; POY F; MARFATIA SM; CHISHTI AH; LIDDINGTON RC
      CRYSTAL-STRUCTURE OF A PDZ DOMAIN

      Nature
    59. TOZER EC; LIDDINGTON RC; SUTCLIFFE MJ; SMEETON AH; LOFTUS JC
      LIGAND-BINDING TO INTEGRIN ALPHA(IIB)BETA(3) IS DEPENDENT ON A MIDAS-LIKE DOMAIN IN THE BETA(3) SUBUNIT

      The Journal of biological chemistry
    60. RAMESH V; SYED SEH; FREDERICK RO; SUTCLIFFE MJ; BARNES M; ROBERTS GCK
      NMR-STUDIES OF THE MODE OF BINDING OF COREPRESSORS AND INDUCERS TO ESCHERICHIA-COLI TRP REPRESSOR

      European journal of biochemistry
    61. SUTCLIFFE MJ; WO ZG; OSWALD RE
      3-DIMENSIONAL MODELS OF NON-NMDA GLUTAMATE RECEPTORS

      Biophysical journal
    62. SUTCLIFFE MJ; WO ZG; OSWALD RE
      3-DIMENSIONAL MODELS OF NON-NMDA GLUTAMATE RECEPTORS

      Biophysical journal
    63. MODI S; PAINE MJ; SUTCLIFFE MJ; LIAN LY; PRIMROSE WU; WOLF CR; ROBERTS GCK
      A MODEL FOR HUMAN CYTOCHROME-P-450 2D6 BASED ON HOMOLOGY MODELING ANDNMR-STUDIES OF SUBSTRATE-BINDING

      Biochemistry
    64. FELTHAM JL; SUTCLIFFE MJ; CERIONE RA; WAGNER G; OSWALD RE
      HETERONUCLEAR NMR AND MODELING STUDIES OF THE RAS-LIKE GTP-BINDING PROTEIN CDC42HS

      Protein engineering
    65. MURRAY IA; CANN PA; DAY PJ; DERRICK JP; SUTCLIFFE MJ; SHAW WV; LESLIE AGW
      STEROID RECOGNITION BY CHLORAMPHENICOL ACETYLTRANSFERASE - ENGINEERING AND STRUCTURAL-ANALYSIS OF A HIGH-AFFINITY FUSIDIC ACID-BINDING SITE

      Journal of Molecular Biology
    66. BAGSHAW CR; SUTCLIFFE MJ
      ANOTHER TURN FOR E-F HANDS

      Nature structural biology
    67. SUTCLIFFE MJ; JASEJA M; HYDE EI; LU XJ; WILLIAMS JA
      3-DIMENSIONAL STRUCTURE OF THE RGD-CONTAINING NEUROTOXIN HOMOLOG DENDROASPIN

      Nature structural biology
    68. BROWN KA; SUTCLIFFE MJ; STEEL KP; BROWN SDM
      SEQUENCING OF THE OLFACTORY MARKER PROTEIN GENE IN NORMAL AND SHAKER-1 MUTANT MICE

      Mammalian genome
    69. SUTCLIFFE MJ; STANFIELD PR
      PORE REGION OF K+ CHANNEL RACTKI

      Nature
    70. STANFIELD PR; DAVIES NW; SHELTON PA; SUTCLIFFE MJ; KHAN IA; BRAMMAR WJ; CONLEY EC
      A SINGLE ASPARTATE RESIDUE IS INVOLVED IN BOTH INTRINSIC GATING AND BLOCKAGE BY MG2+ OF THE INWARD RECTIFIER, IRK1

      Journal of physiology
    71. JASEJA M; LU XJ; WILLIAMS JA; SUTCLIFFE MJ; KAKKAR VV; PARSLOW RA; HYDE EI
      H-1-NMR ASSIGNMENTS AND SECONDARY STRUCTURE OF DENDROASPIN, AN RGD-CONTAINING GLYCOPROTEIN IIB-IIIA (ALPHA-IIB-BETA-3) ANTAGONIST WITH A NEUROTOXIN FOLD

      European journal of biochemistry
    72. FELTHAM JL; SUTCLIFFE MJ; MANOR D; CERIONE RA; OSWALD RE
      3-DIMENSIONAL NMR AND MODELING STUDIES OF THE CDC42HS PROTEIN

      Biophysical journal
    73. SUTCLIFFE MJ
      REPRESENTING AN ENSEMBLE OF NMR-DERIVED PROTEIN STRUCTURES BY A SINGLE STRUCTURE

      Protein science
    74. SUTCLIFFE MJ; MUELLER OT; GALLARDO LA; PAPENHAUSEN PR; TEDESCO TA
      MATERNAL ISODISOMY 16 IN A NORMAL 46, XX FOLLOWING TRISOMIC CONCEPTION

      American journal of human genetics


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Documento generato il 20/10/20 alle ore 14:37:15