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La ricerca find articoli where authors phrase all words ' SHEARDOWN MJ' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 54 riferimenti
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    1. Rasmussen, T; Fink-Jensen, A; Sauerberg, P; Swedberg, MDB; Thomsen, C; Sheardown, MJ; Jeppesen, L; Calligaro, DO; DeLapp, NW; Whitesitt, C; Ward, JS; Shannon, HE; Bymaster, FP
      The muscarinic receptor agonist BuTAC, a novel potential antipsychotic, does not impair learning and memory in mouse passive avoidance

      SCHIZOPHRENIA RESEARCH
    2. Stanhope, KJ; Mirza, NR; Bickerdike, MJ; Bright, JL; Harrington, NR; Hesselink, MB; Kennett, GA; Lightowler, S; Sheardown, MJ; Syed, R; Upton, RL; Wadsworth, G; Weiss, SM; Wyatt, A
      The muscarinic receptor agonist xanomeline has an anti psychotic-like profile in the rat

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    3. Porter, RHP; Malcolm, CS; Allen, NH; Lamb, H; Revell, DF; Sheardown, MJ
      Agonist-induced functional desensitization of recombinant human 5-HT2 receptors expressed in CHO-K1 cells

      BIOCHEMICAL PHARMACOLOGY
    4. Shannon, HE; Rasmussen, K; Bymaster, FP; Hart, JC; Peters, SC; Swedberg, MDB; Jeppesen, L; Sheardown, MJ; Sauerberg, P; Fink-Jensen, A
      Xanomeline, an M-1/M-4 preferring muscarinic cholinergic receptor agonist,produces antipsychotic-like activity in rats and mice

      SCHIZOPHRENIA RESEARCH
    5. Rasmussen, T; Sauerberg, P; Nielsen, EB; Swedberg, MDB; Thomsen, C; Sheardown, MJ; Jeppesen, L; Calligaro, DO; DeLapp, NW; Whitesitt, C; Ward, JS; Shannon, HE; Bymaster, FP; Fink-Jensen, A
      Muscarinic receptor agonists decrease cocaine self-administration rates indrug-naive mice

      EUROPEAN JOURNAL OF PHARMACOLOGY
    6. Empson, RM; Sheardown, MJ; Newberry, NR
      Modulation of gamma-aminobutyric acid responses in the rat optic nerve

      EUROPEAN JOURNAL OF PHARMACOLOGY
    7. Empson, RM; Gee, VJ; Sheardown, MJ; Newberry, NR
      Chlormethiazole inhibits epileptiform activity by potentiating GABA(A) receptor function

      BRAIN RESEARCH
    8. Shannon, HE; Hart, JC; Bymaster, FP; Calligaro, DO; Delapp, NW; Mitch, CH; Ward, JS; Fink-Jensen, A; Sauerberg, P; Jeppesen, L; Sheardown, MJ; Swedberg, MDB
      Muscarinic receptor agonists, like dopamine receptor antagonist antipsychotics, inhibit conditioned avoidance response in rats

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    9. Knutsen, LJS; Lau, J; Petersen, H; Thomsen, C; Weis, JU; Shalmi, M; Judge, ME; Hansen, AJ; Sheardown, MJ
      N-substituted adenosines as novel neuroprotective A(1) agonists with diminished hypotensive effects

      JOURNAL OF MEDICINAL CHEMISTRY
    10. Jeppesen, L; Olesen, PH; Hansen, L; Sheardown, MJ; Thomsen, C; Rasmussen, T; Jensen, AF; Christensen, MS; Rimvall, K; Ward, JS; Whitesitt, C; Calligaro, DO; Bymaster, FP; Delapp, NW; Felder, CC; Shannon, HE; Sauerberg, P
      1-(1,2,5-thiadiazol-4-yl)-4-azatricyclo[2.2.1.0(2,6)]heptanes as new potent muscarinic M-1 agonists: Structure-activity relationship for 3-aryl-2-propyn-1-yloxy and 3-aryl-2-propyn-1-ylthio derivatives

      JOURNAL OF MEDICINAL CHEMISTRY
    11. Porter, RHP; Benwell, KR; Lamb, H; Malcolm, CS; Allen, NH; Revell, DF; Adams, DR; Sheardown, MJ
      Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells

      BRITISH JOURNAL OF PHARMACOLOGY
    12. SAUERBERG P; JEPPESEN L; OLESEN PH; SHEARDOWN MJ; FINKJENSEN A; RASMUSSEN T; RIMVALL K; SHANNON HE; BYMASTER FP; DELAPP NW; CALLIGARO DO; WARD JS; WHITESITT CA; THOMSEN C
      IDENTIFICATION OF SIDE-CHAINS ON 1,2,5-THIADIAZOLE-AZACYCLES OPTIMAL FOR MUSCARINIC M1 RECEPTOR ACTIVATION

      Bioorganic & medicinal chemistry letters
    13. Fink-Jensen, A; Kristensen, P; Shannon, HE; Calligaro, DO; Delapp, NW; Whitesitt, C; Ward, JS; Thomsen, C; Rasmusseen, T; Sheardown, MJ; Jeppesen, L; Sauerberg, P; Bymaster, FP
      Muscarinic agonists exhibit functional dopamine antagonism in unilaterally6-OHDA lesioned rats

      NEUROREPORT
    14. Knutsen, LJS; Sheardown, MJ; Roberts, SM; Mogensen, JP; Olsen, UB; Thomsen, C; Bowler, AN
      Adenosine A(1) and A(3) selective N-alkoxypurines as novel cytokine modulators and neuroprotectants

      DRUG DEVELOPMENT RESEARCH
    15. WARD JS; MERRITT L; CALLIGARO DO; BYMASTER FP; SHANNON HE; MITCH CH; WHITESITT C; BRUNSTING D; SHEARDOWN MJ; OLESEN PH; SWEDBERG MDB; JEPPESEN L; SAUERBERG P
      1,2,5-THIADIAZOLE ANALOGS OF ACECLIDINE AS POTENT M(1) MUSCARINIC AGONISTS

      Journal of medicinal chemistry
    16. SAUERBERG P; JEPPESEN L; OLESEN PH; RASMUSSEN T; SWEDBERG MDB; SHEARDOWN MJ; FINKJENSEN A; THOMSEN C; THOGERSEN H; RIMVALL K; WARD JS; CALLIGARO DO; DELAPP NW; BYMASTER FP; SHANNON HE
      MUSCARINIC AGONISTS WITH ANTIPSYCHOTIC-LIKE ACTIVITY - STRUCTURE-ACTIVITY-RELATIONSHIPS OF 1,2,5-THIADIAZOLE ANALOGS WITH FUNCTIONAL DOPAMINE ANTAGONIST ACTIVITY

      Journal of medicinal chemistry
    17. SAUERBERG P; OLESEN PH; SHEARDOWN MJ; RIMVALL K; THOGERSEN H; SHANNON HE; SAWYER BD; WARD JS; BYMASTER FP; DELAPP NW; CALLIGARO DO; SWEDBERG MDB
      CONFORMATIONALLY CONSTRAINED ANALOGS OF THE MUSCARINIC AGONIST IADIAZOL-3-YL)-1,2,5,6-TETRAHYDRO-1-METHYLPYRIDINE - SYNTHESIS, RECEPTOR AFFINITY, AND ANTINOCICEPTIVE ACTIVITY

      Journal of medicinal chemistry
    18. BYMASTER FP; SHANNON HE; RASMUSSEN K; DELAPP NW; MITCH CH; WARD JS; CALLIGARO DO; LUDVIGSEN TS; SHEARDOWN MJ; OLESEN PH; SWEDBERG MDB; SAUERBERG P; FINKJENSEN A
      UNEXPECTED ANTIPSYCHOTIC-LIKE ACTIVITY WITH THE MUSCARINIC RECEPTOR-LIGAND O-1,2,5-THIADIAZOL-4-YL)-1-AZABICYCLO[3.2.1]OCTANE

      European journal of pharmacology
    19. CASTILLO GM; CUMMINGS JA; YANG WH; JUDGE ME; SHEARDOWN MJ; RIMVALL K; HANSEN JB; SNOW AD
      SULFATE CONTENT AND SPECIFIC GLYCOSAMINOGLYCAN BACKBONE OF PERLECAN ARE CRITICAL FOR PERLECANS ENHANCEMENT OF ISLET AMYLOID POLYPEPTIDE (AMYLIN) FIBRIL FORMATION

      Diabetes
    20. BYMASTER FP; CARTER PA; PETERS SC; ZHANG W; WARD JS; MITCH CH; CALLIGARO DO; WHITESITT CA; DELAPP N; SHANNON HE; RIMVALL K; JEPPESEN L; SHEARDOWN MJ; FINKJENSEN A; SAUERBERG P
      XANOMELINE COMPARED TO OTHER MUSCARINIC AGENTS ON STIMULATION OF PHOSPHOINOSITIDE HYDROLYSIS IN-VIVO AND OTHER CHOLINOMIMETIC EFFECTS

      Brain research
    21. OLESEN PH; SWEDBERG MDB; ESKESEN K; JUDGE ME; EGEBJERG J; TONDER JE; RASMUSSEN T; SHEARDOWN MJ; RIMVALL K
      IDENTIFICATION OF NOVEL (ISOXAZOLE)METHYLENE-1-AZABICYCLIC COMPOUNDS WITH HIGH-AFFINITY FOR THE CENTRAL NICOTINIC CHOLINERGIC RECEPTOR

      Bioorganic & medicinal chemistry letters
    22. BYMASTER FP; WHITESITT CA; SHANNON HE; DELAPP N; WARD JS; CALLIGARO DO; SHIPLEY LA; BUELKESAM JL; BODICK NC; FARDE L; SHEARDOWN MJ; OLESEN PH; HANSEN KT; SUZDAK PD; SWEDBERG MDB; SAUERBERG P; MITCH CH
      XANOMELINE - A SELECTIVE MUSCARINIC AGONIST FOR THE TREATMENT OF ALZHEIMERS-DISEASE

      Drug development research
    23. SHEARDOWN MJ; KNUTSEN LJS
      UNEXPECTED NEUROPROTECTION OBSERVED WITH THE ADENOSINE A(2A) RECEPTORAGONIST CGS-21680 (VOL 39, PG 108, 1996)

      Drug development research
    24. SAUERBERG P; OLESEN PH; THOGERSEN H; NIELSEN S; SHEARDOWN MJ; RIMVALL K; SHANNON HE; WARD JS; MITCH CH; BYMASTER FP; SWEDBERG MDB
      CONFORMATIONALLY CONSTRAINED ANALOGS OF THE MUSCARINIC AGONIST METHYLTHIO-TZTP - SYNTHESIS, RECEPTOR AFFINITY AND ANALGESIC ACTIVITY

      Life sciences
    25. WARD JS; MERRITT L; STRATFORD R; BROWN TJ; WIJAYARATNE R; SZEWCZYK SP; CALLIGARO DO; BYMASTER FP; SHANNON HE; MITCH CH; JOHNSON DW; WIKEL JH; OLESEN MJ; SHEARDOWN MJ; SWEDBERG MDB; SAUERBERG P
      THE TETRAHYDROPYRIDINE RING CONFERS OPTIMAL M(1) SELECTIVITY AND BLOOD-BRAIN-BARRIER PENETRATION AMONG HEXYLOXY-1,2,5-THIADIAZOLE AZACYCLES

      Life sciences
    26. SHANNON HE; WOMER DE; DELAPP NW; BYMASTER FP; MITCH CH; WARD JS; WHITESITT C; CALLIGARO D; SWEDBERG MDB; SHEARDOWN MJ; SAUERBERG P; RIMVALL K; FINKJENSEN A; JEPPESEN L
      MUSCARINIC AGONISTS PRODUCE ANALGESIA THROUGH PERTUSSIS-TOXIN-SENSITIVE MUSCARINIC RECEPTORS IN THE SPINAL-CORD

      Life sciences
    27. SWEDBERG MDB; SHANNON HE; SHEARDOWN MJ; KLITGAARD H; BYMASTER FP; WARD JS; MITCH CH; OLESEN PH; ESKESEN K; SUZDAK PD; CALLIGARO DO; SAUERBERG P
      ANTICONVULSANT EFFECTS OF MUSCARINICS

      Life sciences
    28. SHANNON HE; WOMER DE; BYMASTER FP; CALLIGARO DO; DELAPP NC; MITCH CH; WARD JS; WHITESITT CA; SWEDBERG MDB; SHEARDOWN MJ; FINKJENSEN A; OLESEN PH; RIMVALL K; SAUERBERG P
      IN-VIVO PHARMACOLOGY OF BUTYLTHIO[2.2.2] (LY297802 NNC11-1053), AN ORALLY ACTING ANTINOCICEPTIVE MUSCARINIC AGONIST/

      Life sciences
    29. SHEARDOWN MJ; SHANNON HE; SWEDBERG MDB; SUZDAK PD; BYMASTER FP; OLESEN PH; MITCH CH; WARD JS; SAUERBERG P
      M-1 RECEPTOR AGONIST ACTIVITY IS NOT A REQUIREMENT FOR MUSCARINIC ANTINOCICEPTION

      The Journal of pharmacology and experimental therapeutics
    30. SWEDBERG MDB; SHEARDOWN MJ; SAUERBERG P; OLESEN PH; SUZDAK PD; HANSEN KT; BYMASTER FP; WARD JS; MITCH CH; CALLIGARO DO; DELAPP NW; SHANNON HE
      BUTYLTHIO[2.2.2] (NNC 11-1053 LY297802) - AN ORALLY-ACTIVE MUSCARINICAGONIST ANALGESIC/

      The Journal of pharmacology and experimental therapeutics
    31. SHANNON HE; SHEARDOWN MJ; BYMASTER FP; CALLIGARO DO; DELAPP NW; GIDDA J; MITCH CH; SAWYER BD; STENGEL PW; WARD JS; WONG DT; OLESEN PH; SUZDAK PD; SAUERBERG P; SWEDBERG MDB
      PHARMACOLOGY OF BUTYLTHIO[2.2.2] (LY297802 NNC11-1053) - A NOVEL ANALGESIC WITH MIXED MUSCARINIC RECEPTOR AGONIST AND ANTAGONIST ACTIVITY/

      The Journal of pharmacology and experimental therapeutics
    32. MITCH CH; BROWN TJ; BYMASTER FP; CALLIGARO DO; DIECKMAN D; MERRIT L; PETERS SC; QUIMBY SJ; SHANNON HE; SHIPLEY LA; WARD JS; HANSEN K; OLESEN PH; SAUERBERG P; SHEARDOWN MJ; SWEDBERG MDB; SUZDAK P; GREENWOOD B
      MUSCARINIC ANALGESICS WITH POTENT AND SELECTIVE EFFECTS ON THE GASTROINTESTINAL-TRACT - POTENTIAL APPLICATION FOR THE TREATMENT OF IRRITABLE-BOWEL-SYNDROME

      Journal of medicinal chemistry
    33. SHEARDOWN MJ
      THE TRIGGERING OF SPREADING DEPRESSION IN THE CHICK RETINA BY NICOTINIC RECEPTOR AGONISTS

      European journal of pharmacology
    34. SHEARDOWN MJ; THOMSEN C
      PHENYLGLYCINES CAN EVOKE QUISQUALATE-PRIMED DEPOLARIZATIONS IN RAT CINGULATE CORTEX - AN EFFECT ASSOCIATED WITH [H-3] DL-AP4 UPTAKE

      European journal of neuroscience
    35. SHEARDOWN MJ; KNUTSEN LJS
      UNEXPECTED NEUROPROTECTION OBSERVED WITH THE ADENOSINE A(2A) RECEPTORAGONIST CGS-21680

      Drug development research
    36. OLESEN PH; SAUERBERG P; TREPPENDAHL S; LARSSON O; SHEARDOWN MJ; SUZDAK PD; MITCH CH; WARD JS; BYMASTER FP; SHANNON HE; SWEDBERG MDB
      3-(3-ALKYLTHIO-1,2,5-THIADIAZOL-4-YL)1-AZABICYCLE - STRUCTURE-ACTIVITY-RELATIONSHIPS FOR ANTINOCICEPTION MEDIATED BY CENTRAL MUSCARINIC RECEPTORS

      European journal of medicinal chemistry
    37. SAUERBERG P; OLESEN PH; SHEARDOWN MJ; SUZDAK PD; SHANNON HE; BYMASTER FP; CALLIGARO DO; MITCH CH; WARD JS; SWEDBERG MDB
      MUSCARINIC AGONISTS AS ANALGESICS - ANTINOCICEPTIVE ACTIVITY VERSUS M(1) ACTIVITY - SAR OF ALKYLTHIO-TZTPS AND RELATED 1,2,5-THIADIAZOLE ANALOGS

      Life sciences
    38. WARD JS; MERRITT L; CALLIGARO DO; BYMASTER FP; SHANNON HE; SAWYER BD; MITCH CH; SHEARDOWN MJ; OLESEN PH; SUZDAK PD; SWEDBERG MDB
      3-(3-HEXYLOXYPYRAZINYL) QUINUCLIDINE AS A FUNCTIONALLY SELECTIVE M(1)AGONIST

      Life sciences
    39. SAWYER BD; SHANNON HE; WARD JS; MITCH CH; SHEARDOWN MJ; OLESEN PH; SAUERBERG P
      MUSCARINIC RECEPTOR CHARACTERIZATION AND EVALUATION OF A SERIES OF NOVEL MUSCARINIC LIGANDS IN THE ISOLATED RABBIT THORACIC AORTA

      Life sciences
    40. MITCH CH; BYMASTER FP; CALLIGARO DO; QUIMBY SJ; SAWYER BD; WARD JS; OLESEN PH; SAUERBERG P; SHEARDOWN MJ; SUZDAK PD; SWEDBERG M; SHANNON HE
      SIDE-CHAIN STERIC BULK AND MUSCARINIC AGONIST SAR IN ALKOXY-TZTPS

      Life sciences
    41. SHANNON HE; BYMASTER FP; CALLIGARO DO; MITCH CH; SAWYER BD; WARD JS; SHEARDOWN MJ; OLESEN PH; SAUERBERG P; SUZDAK PD; SWEDBERG MDB
      IN-VITRO PHARMACOLOGY OF THE MUSCARINIC ANALGESIC LY297802 NNC111053/

      Life sciences
    42. SWEDBERG MDB; SHEARDOWN MJ; SAUERBERG P; OLESEN P; SUZDAK PD; BYMASTER FP; WARD JS; MITCH CH; CALLIGARO DO; SHANNON HE
      NNC-11-1053 LY-297802 - AN ANTINOCICEPTIVE ORALLY ACTING MUSCARINIC AGONIST IN MOUSE AND RAT

      Life sciences
    43. WARD JS; MERRITT L; CALLIGARO DO; BYMASTER FP; SHANNON HE; SAWYER BD; MITCH CH; DEETER JB; PETERS SC; SHEARDOWN MJ; OLESEN PH; SWEDBERG MDB; SAUERBERG P
      FUNCTIONALLY SELECTIVE M(1) MUSCARINIC AGONISTS .3. SIDE-CHAINS AND AZACYCLES CONTRIBUTING TO FUNCTIONAL MUSCARINIC SELECTIVITY AMONG PYRAZINYLAZACYCLES

      Journal of medicinal chemistry
    44. QUIMBY SJ; SHANNON HE; BYMASTER FP; SAUERBERG P; OLESEN PH; SHEARDOWN MJ; SUZDAK PD; MITCH CH
      SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF ALKYL SUBSTITUTED ANALOGS OF THE FUNCTIONAL M(1) SELECTIVE MUSCARINIC RECEPTOR AGONIST XANOMELINE

      Bioorganic & medicinal chemistry letters
    45. MITCH CH; BYMASTER FP; CALLIGARO DO; QUIMBY SJ; SAWYER BD; SHANNON HE; WARD JS; OLESEN PH; SAUERBERG P; SHEARDOWN MJ; SUZDAK PD
      XANOMELINE - A POTENT AND SELECTIVE M1 MUSCARINIC AGONIST IN-VITRO

      Neurobiology of aging
    46. BARONE FC; PRICE WJ; JAKOBSEN P; SHEARDOWN MJ; FEUERSTEIN G
      PHARMACOLOGICAL PROFILE OF A NOVEL NEURONAL CALCIUM-CHANNEL BLOCKER INCLUDES REDUCED CEREBRAL-DAMAGE AND NEUROLOGICAL DEFICITS IN RAT FOCALISCHEMIA

      Pharmacology, biochemistry and behavior
    47. SHANNON HE; BYMASTER FP; CALLIGARO DO; GREENWOOD B; MITCH CH; SAWYER BD; WARD JS; WONG DT; OLESEN PH; SHEARDOWN MJ; SWEDBERG MDB; SUZDAK PD; SAUERBERG P
      XANOMELINE - A NOVEL MUSCARINIC RECEPTOR AGONIST WITH FUNCTIONAL SELECTIVITY FOR M(1) RECEPTORS

      The Journal of pharmacology and experimental therapeutics
    48. BYMASTER FP; WONG DT; MITCH CH; WARD JS; CALLIGARO DO; SCHOEPP DD; SHANNON HE; SHEARDOWN MJ; OLESEN PH; SUZDAK PD; SWEDBERG MDB; SAUERBERG P
      NEUROCHEMICAL EFFECTS OF THE M(1) MUSCARINIC AGONIST XANOMELINE (LY246708 NNC11-0232)/

      The Journal of pharmacology and experimental therapeutics
    49. KNUTSEN LJS; LAU J; SHEARDOWN MJ; THOMSEN C
      THE SYNTHESIS AND BIOCHEMICAL EVALUATION OF NEW A(1) SELECTIVE ADENOSINE RECEPTOR AGONISTS CONTAINING 6-HYDRAZINOPURINE MOIETIES

      Bioorganic & medicinal chemistry letters
    50. SUZDAK PD; SHEARDOWN MJ; HONORE T
      CHARACTERIZATION OF THE METABOTROPIC GLUTAMATE RECEPTOR IN MOUSE CEREBELLAR GRANULE CELLS - LACK OF EFFECT OF DIHYDROXY-6-NITRO-7-SULPHAMOYLBENZO(F)-QUINOXALINE (NBQX)

      European journal of pharmacology. Molecular pharmacology section
    51. SHEARDOWN MJ
      THE PHARMACOLOGY OF AMPA RECEPTORS AND THEIR ANTAGONISTS

      Stroke
    52. MARCOUX FW; WEILOCH; SHEARDOWN MJ; GOLDBERG; GLOBUS; PULSINELLI; FUTRELL; HAKIM; HACHINSKI VC
      AMPA ANTAGONISTS - DO THEY HOLD MORE PROMISE FOR CLINICAL STROKE TRIALS THAN NMDA ANTAGONISTS - DISCUSSION-2

      Stroke
    53. SUZDAK PD; SHEARDOWN MJ
      EFFECT OF THE NON-NMDA RECEPTOR ANTAGONIST, ,3-DIHYDRO-6-NITRO-7-SULFAMOYLBENZO(F)QUINOXALINE, ON LOCAL CEREBRAL GLUCOSE-UPTAKE IN THE LIMBIC FOREBRAIN

      Journal of neurochemistry
    54. SHEARDOWN MJ; SUZDAK PD; NORDHOLM L
      AMPA, BUT NOT NMDA, RECEPTOR ANTAGONISM IS NEUROPROTECTIVE IN GERBIL GLOBAL-ISCHEMIA, EVEN WHEN DELAYED 24-H

      European journal of pharmacology


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Documento generato il 31/05/20 alle ore 10:37:15