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1. Alauddin, MM; Shahinian, A; Gordon, EM; Bading, JR; Conti, PS
   Preclinical evaluation of the penciclovir analog 9-(4-[F-18] fluoro-3-hydroxymethylbutyl)guanine for in vivo measurement of suicide gene expression with PET
   JOURNAL OF NUCLEAR MEDICINE
   
   M.M. Alauddin et al., "Preclinical evaluation of the penciclovir analog 9-(4-[F-18] fluoro-3-hydroxymethylbutyl)guanine for in vivo measurement of suicide gene expression with PET", J NUCL MED, 42(11), 2001, pp. 1682-1690
2. Tafuri, A; Shahinian, A; Bladt, F; Yoshinaga, SK; Jordana, M; Wakeham, A; Boucher, LM; Bouchard, D; Chan, VSF; Duncan, G; Odermatt, B; Ho, A; Itie, A; Horan, T; Whoriskey, JS; Pawson, T; Penninger, JM; Ohashi, PS; Mak, TW
   ICOS is essential for effective T-helper-cell responses
   NATURE
   
   A. Tafuri et al., "ICOS is essential for effective T-helper-cell responses", NATURE, 409(6816), 2001, pp. 105-109
3. Bonnard, M; Mirtsos, C; Suzuki, S; Graham, K; Huang, JN; Ng, M; Itie, A; Wakeham, A; Shahinian, A; Henzel, WJ; Elia, AJ; Shillinglaw, W; Mak, TW; Cao, ZD; Yeh, WC
   Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappa B-dependent gene transcription
   EMBO JOURNAL
   
   M. Bonnard et al., "Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappa B-dependent gene transcription", EMBO J, 19(18), 2000, pp. 4976-4985
4. Nguyen, LT; Duncan, GS; Mirtsos, C; Ng, M; Speiser, DE; Shahinian, A; Marino, MW; Mak, TW; Ohashi, PS; Yeh, WC
   TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses
   IMMUNITY
   
   L.T. Nguyen et al., "TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses", IMMUNITY, 11(3), 1999, pp. 379-389
5. Alauddin, MM; Shahinian, A; Kundu, RK; Gordon, EM; Conti, PS
   Evaluation of 9-[(3-F-18-fluoro-1-hydroxy-2-propoxy)methyl]guanine ([F-18]-FHPG) in vitro and in vivo as a probe for PET imaging of gene incorporation and expression in tumors
   NUCLEAR MEDICINE AND BIOLOGY
   
   M.M. Alauddin et al., "Evaluation of 9-[(3-F-18-fluoro-1-hydroxy-2-propoxy)methyl]guanine ([F-18]-FHPG) in vitro and in vivo as a probe for PET imaging of gene incorporation and expression in tumors", NUCL MED BI, 26(4), 1999, pp. 371-376
6. Yoshinaga, SK; Whoriskey, JS; Khare, SD; Sarmiento, U; Guo, J; Horan, T; Shih, G; Zhang, M; Coccia, MA; Kohno, T; Tafuri-Bladt, A; Brankow, D; Campbell, P; Chang, D; Chiu, L; Dai, TN; Duncan, G; Elliott, GS; Hui, A; McCabe, SM; Scully, S; Shahinian, A; Shaklee, CL; Van, G; Mak, TW; Senaldi, G
   T-cell co-stimulation through B7RP-1 and ICOS
   NATURE
   
   S.K. Yoshinaga et al., "T-cell co-stimulation through B7RP-1 and ICOS", NATURE, 402(6763), 1999, pp. 827-832
7. YOSHIDA H; NISHINA H; TAKIMOTO H; MARENGERE LEM; WAKEHAM AC; BOUCHARD D; KONG YY; OHTEKI T; SHAHINIAN A; BACHMANN M; OHASHI PS; PENNINGER JM; CRABTREE GR; MAK TW
   THE TRANSCRIPTION FACTOR NF-ATC1 REGULATES LYMPHOCYTE-PROLIFERATION AND TH2 CYTOKINE PRODUCTION
   Immunity
   
   H. Yoshida et al., "THE TRANSCRIPTION FACTOR NF-ATC1 REGULATES LYMPHOCYTE-PROLIFERATION AND TH2 CYTOKINE PRODUCTION", Immunity, 8(1), 1998, pp. 115-124
8. WOO M; HAKEM R; SOENGAS MS; DUNCAN GS; SHAHINIAN A; KAGI D; HAKEM A; MCCURRACH M; KHOO W; KAUFMAN SA; SENALDI G; HOWARD T; LOWE SW; MAK TW
   ESSENTIAL CONTRIBUTION OF CASPASE-3 CPP32 TO APOPTOSIS AND ITS ASSOCIATED NUCLEAR-CHANGES
   Genes & development
   
   M. Woo et al., "ESSENTIAL CONTRIBUTION OF CASPASE-3 CPP32 TO APOPTOSIS AND ITS ASSOCIATED NUCLEAR-CHANGES", Genes & development, 12(6), 1998, pp. 806-819
9. YEH WC; DELAPOMPA JL; MCCURRACH ME; SHU HB; ELIA AJ; SHAHINIAN A; NG M; WAKEHAM A; KHOO W; MITCHELL K; ELDEIRY WS; LOWE SW; GOEDDEL DV; MAK TW
   FADD - ESSENTIAL FOR EMBRYO DEVELOPMENT AND SIGNALING FROM SOME, BUT NOT ALL, INDUCERS OF APOPTOSIS
   Science
   
   W.C. Yeh et al., "FADD - ESSENTIAL FOR EMBRYO DEVELOPMENT AND SIGNALING FROM SOME, BUT NOT ALL, INDUCERS OF APOPTOSIS", Science, 279(5358), 1998, pp. 1954-1958
10. YEH WC; SHAHINIAN A; SPEISER D; KRAUNUS J; BILLIA F; WAKEHAM A; DELAPOMPA JL; FERRICK D; HUM B; ISCOVE N; OHASHI P; ROTHE M; GOEDDEL DV; MAK TW
    EARLY LETHALITY, FUNCTIONAL NF-KAPPA-B ACTIVATION, AND INCREASED SENSITIVITY TO TNF-INDUCED CELL-DEATH IN TRAF2-DEFICIENT MICE
    Immunity
    
    W.C. Yeh et al., "EARLY LETHALITY, FUNCTIONAL NF-KAPPA-B ACTIVATION, AND INCREASED SENSITIVITY TO TNF-INDUCED CELL-DEATH IN TRAF2-DEFICIENT MICE", Immunity, 7(5), 1997, pp. 715-725
11. SPEISER DE; BACHMANN MF; SHAHINIAN A; MAK TW; OHASHI PS
    ACUTE GRAFT-VERSUS-HOST DISEASE WITHOUT COSTIMULATION VIA CD28
    Transplantation
    
    D.E. Speiser et al., "ACUTE GRAFT-VERSUS-HOST DISEASE WITHOUT COSTIMULATION VIA CD28", Transplantation, 63(7), 1997, pp. 1042-1044
12. MITTRUCKER HW; MATSUYAMA T; GROSSMAN A; KUNDIG TM; POTTER J; SHAHINIAN A; WAKEHAM A; PATTERSON B; OHASHI PS; MAK TW
    REQUIREMENT FOR THE TRANSCRIPTION FACTOR LSIRF IRF4 FOR MATURE B-LYMPHOCYTE AND T-LYMPHOCYTE FUNCTION/
    Science
    
    H.W. Mittrucker et al., "REQUIREMENT FOR THE TRANSCRIPTION FACTOR LSIRF IRF4 FOR MATURE B-LYMPHOCYTE AND T-LYMPHOCYTE FUNCTION/", Science, 275(5299), 1997, pp. 540-543
13. NISHINA H; FISCHER KD; RADVANYI L; SHAHINIAN A; HAKEM R; RUBIE EA; BERNSTEIN A; MAK TW; WOODGETT JR; PENNINGER JM
    STRESS-SIGNALING KINASE SEK1 PROTECTS THYMOCYTES FROM APOPTOSIS MEDIATED BY CD95 AND CD3
    Nature
    
    H. Nishina et al., "STRESS-SIGNALING KINASE SEK1 PROTECTS THYMOCYTES FROM APOPTOSIS MEDIATED BY CD95 AND CD3", Nature, 385(6614), 1997, pp. 350-353
14. WALLACE VA; PENNINGER JM; KISHIHARA K; TIMMS E; SHAHINIAN A; PIRCHER H; KUNDIG TM; OHASHI PS; MAK TW
    ALTERATIONS IN THE LEVEL OF CD45 SURFACE EXPRESSION AFFECT THE OUTCOME OF THYMIC SELECTION
    The Journal of immunology
    
    V.A. Wallace et al., "ALTERATIONS IN THE LEVEL OF CD45 SURFACE EXPRESSION AFFECT THE OUTCOME OF THYMIC SELECTION", The Journal of immunology, 158(7), 1997, pp. 3205-3214
15. DEBENEDETTE MA; SHAHINIAN A; MAK TW; WATTS TH
    COSTIMULATION OF CD28(-) T-LYMPHOCYTES BY 4-1BB LIGAND
    The Journal of immunology
    
    M.A. Debenedette et al., "COSTIMULATION OF CD28(-) T-LYMPHOCYTES BY 4-1BB LIGAND", The Journal of immunology, 158(2), 1997, pp. 551-559
16. NISHINA H; BACHMANN M; OLIVEIRADOSSANTOS AJ; KOZIERADZKI I; FISCHER KD; ODERMATT B; WAKEHAM A; SHAHINIAN A; TAKIMOTO H; BERNSTEIN A; MAK TW; WOODGETT JR; OHASHI PS; PENNINGER JM
    IMPAIRED CD28-MEDIATED INTERLEUKIN-2 PRODUCTION AND PROLIFERATION IN STRESS KINASE SAPK ERK1 KINASE (SEK1) MITOGEN-ACTIVATED PROTEIN-KINASEKINASE-4 (MKK4)-DEFICIENT T-LYMPHOCYTES/
    The Journal of experimental medicine
    
    H. Nishina et al., "IMPAIRED CD28-MEDIATED INTERLEUKIN-2 PRODUCTION AND PROLIFERATION IN STRESS KINASE SAPK ERK1 KINASE (SEK1) MITOGEN-ACTIVATED PROTEIN-KINASEKINASE-4 (MKK4)-DEFICIENT T-LYMPHOCYTES/", The Journal of experimental medicine, 186(6), 1997, pp. 941-953
17. WEN T; KONO K; SHAHINIAN A; KIESSLING R; MAK TW; KLEIN G
    CD28 IS NOT REQUIRED FOR REJECTION OF UNMANIPULATED SYNGENEIC AND AUTOLOGOUS TUMORS
    European Journal of Immunology
    
    T. Wen et al., "CD28 IS NOT REQUIRED FOR REJECTION OF UNMANIPULATED SYNGENEIC AND AUTOLOGOUS TUMORS", European Journal of Immunology, 27(8), 1997, pp. 1988-1993
18. SCHMITS R; FILMUS J; GERWIN N; SENALDI G; KIEFER F; KUNDIG T; WAKEHAM A; SHAHINIAN A; CATZAVELOS C; RAK J; FURLONGER C; ZAKARIAN A; SIMARD JJL; OHASHI PS; PAIGE CJ; GUTIERREZRAMOS JC; MAK TW
    CD44 REGULATES HEMATOPOIETIC PROGENITOR DISTRIBUTION, GRANULOMA-FORMATION, AND TUMORIGENICITY
    Blood
    
    R. Schmits et al., "CD44 REGULATES HEMATOPOIETIC PROGENITOR DISTRIBUTION, GRANULOMA-FORMATION, AND TUMORIGENICITY", Blood, 90(6), 1997, pp. 2217-2233
19. KUNDIG TM; SHAHINIAN A; KAWAI K; MITTRUCKER HW; SEBZDA E; BACHMANN MF; MAK TW; OHASHI PS
    DURATION OF TCR STIMULATION DETERMINES COSTIMULATORY REQUIREMENT OF T-CELLS
    Immunity
    
    T.M. Kundig et al., "DURATION OF TCR STIMULATION DETERMINES COSTIMULATORY REQUIREMENT OF T-CELLS", Immunity, 5(1), 1996, pp. 41-52
20. BACHMANN MF; SEBZDA E; KUENDIG TM; SHAHINIAN A; SPEISER D; MAK TW; OHASHI PS
    T-CELL RESPONSES ARE GOVERNED BY AVIDITY AND COSTIMULATORY THRESHOLDS
    The FASEB journal
    
    M.F. Bachmann et al., "T-CELL RESPONSES ARE GOVERNED BY AVIDITY AND COSTIMULATORY THRESHOLDS", The FASEB journal, 10(6), 1996, pp. 2612-2612
21. AMAKAWA R; HAKEM A; KUNDIG TM; MATSUYAMA T; SIMARD JJL; TIMMS E; WAKEHAM A; MITTRUECKER HW; GRIESSER H; TAKIMOTO H; SCHMITS R; SHAHINIAN A; OHASHI PS; PENNINGER JM; MAK TW
    IMPAIRED NEGATIVE SELECTION OF T-CELLS IN HODGKINS-DISEASE ANTIGEN CD30-DEFICIENT MICE
    Cell
    
    R. Amakawa et al., "IMPAIRED NEGATIVE SELECTION OF T-CELLS IN HODGKINS-DISEASE ANTIGEN CD30-DEFICIENT MICE", Cell, 84(4), 1996, pp. 551-562
22. KAWAI K; SHAHINIAN A; MAK TW; OHASHI PS
    SKIN ALLOGRAFT-REJECTION IN CD28-DEFICIENT MICE
    Transplantation
    
    K. Kawai et al., "SKIN ALLOGRAFT-REJECTION IN CD28-DEFICIENT MICE", Transplantation, 61(3), 1996, pp. 352-355
23. BACHMAIER K; PUMMERER C; SHAHINIAN A; IONESCU J; NEU N; MAK TW; PENNINGER JM
    INDUCTION OF AUTOIMMUNITY IN THE ABSENCE OF CD28 COSTIMULATION
    The Journal of immunology
    
    K. Bachmaier et al., "INDUCTION OF AUTOIMMUNITY IN THE ABSENCE OF CD28 COSTIMULATION", The Journal of immunology, 157(4), 1996, pp. 1752-1757
24. MITTRUCKER HW; SHAHINIAN A; BOUCHARD D; KUNDIG TM; MAK TW
    INDUCTION OF UNRESPONSIVENESS AND IMPAIRED T-CELL EXPANSION BY STAPHYLOCOCCAL-ENTEROTOXIN-B IN CD28-DEFICIENT MICE
    The Journal of experimental medicine
    
    H.W. Mittrucker et al., "INDUCTION OF UNRESPONSIVENESS AND IMPAIRED T-CELL EXPANSION BY STAPHYLOCOCCAL-ENTEROTOXIN-B IN CD28-DEFICIENT MICE", The Journal of experimental medicine, 183(6), 1996, pp. 2481-2488
25. SCHMITS R; KUNDIG TM; BAKER DM; SHUMAKER G; SIMARD JJL; DUNCAN G; WAKEHAM A; SHAHINIAN A; VANDERHEIDEN A; BACHMANN MF; OHASHI PS; MAK TW; HICKSTEIN DD
    LFA-1-DEFICIENT MICE SHOW NORMAL CTL RESPONSES TO VIRUS BUT FAIL TO REJECT IMMUNOGENIC TUMOR
    The Journal of experimental medicine
    
    R. Schmits et al., "LFA-1-DEFICIENT MICE SHOW NORMAL CTL RESPONSES TO VIRUS BUT FAIL TO REJECT IMMUNOGENIC TUMOR", The Journal of experimental medicine, 183(4), 1996, pp. 1415-1426
26. BACHMANN MF; SEBZDA E; KUNDIG TM; SHAHINIAN A; SPEISER DE; MAK TW; OHASHI PS
    T-CELL RESPONSES ARE GOVERNED BY AVIDITY AND COSTIMULATORY THRESHOLDS
    European Journal of Immunology
    
    M.F. Bachmann et al., "T-CELL RESPONSES ARE GOVERNED BY AVIDITY AND COSTIMULATORY THRESHOLDS", European Journal of Immunology, 26(9), 1996, pp. 2017-2022
27. WATERHOUSE P; PENNINGER JM; TIMMS E; WAKEHAM A; SHAHINIAN A; LEE KP; THOMPSON CB; GRIESSER H; MAK TW
    LYMPHOPROLIFERATIVE DISORDERS WITH EARLY LETHALITY IN MICE DEFICIENT IN CTLA-4
    Science
    
    P. Waterhouse et al., "LYMPHOPROLIFERATIVE DISORDERS WITH EARLY LETHALITY IN MICE DEFICIENT IN CTLA-4", Science, 270(5238), 1995, pp. 985-988
28. PENNINGER JM; TIMMS E; SHAHINIAN A; JEZOBREMOND A; NISHINA H; IONESCU J; HEDRICK SM; MAK TW
    ALLOREACTIVE GAMMA-DELTA THYMOCYTES UTILIZE DISTINCT COSTIMULATORY SIGNALS FROM PERIPHERAL T-CELLS
    The Journal of immunology
    
    J.M. Penninger et al., "ALLOREACTIVE GAMMA-DELTA THYMOCYTES UTILIZE DISTINCT COSTIMULATORY SIGNALS FROM PERIPHERAL T-CELLS", The Journal of immunology, 155(8), 1995, pp. 3847-3855
29. PFEFFER K; MATSUYAMA T; KUNDIG TM; WAKEHAM A; KISHIHARA K; SHAHINIAN A; WIEGMANN K; OHASHI PS; KRONKE M; MAK TW
    MICE DEFICIENT FOR THE 55-KDA RECEPTOR FOR TUMOR-NECROSIS-FACTOR ARE RESISTANT TO ENDOTOXIC-SHOCK YET SUCCUMB TO LISTERIA-MONOCYTOGENES INFECTION
    Journal of cellular biochemistry
    
    K. Pfeffer et al., "MICE DEFICIENT FOR THE 55-KDA RECEPTOR FOR TUMOR-NECROSIS-FACTOR ARE RESISTANT TO ENDOTOXIC-SHOCK YET SUCCUMB TO LISTERIA-MONOCYTOGENES INFECTION", Journal of cellular biochemistry, 1994, pp. 393-393
30. KUNDIG TM; SHAHINIAN A; PFEFFER K; ZINKERNAGEL RM; HORAK I; MAK TW; OHASHI PS
    ANTIVIRAL IMMUNE RESPONSIVENESS IN INTERLEUKIN-2 AND IN CD28 DEFICIENT MICE
    Journal of cellular biochemistry
    
    T.M. Kundig et al., "ANTIVIRAL IMMUNE RESPONSIVENESS IN INTERLEUKIN-2 AND IN CD28 DEFICIENT MICE", Journal of cellular biochemistry, 1994, pp. 429-429
31. SHAHINIAN A; PFEFFER K; LEE KP; KUNDIG TM; KISHIHARA K; WAKEHAM A; KAWAI K; OHASHI PS; THOMPSON CB; MAK TW
    DIFFERENTIAL T-CELL COSTIMULATORY REQUIREMENTS IN CD28-DEFICIENT MICE
    Journal of cellular biochemistry
    
    A. Shahinian et al., "DIFFERENTIAL T-CELL COSTIMULATORY REQUIREMENTS IN CD28-DEFICIENT MICE", Journal of cellular biochemistry, 1994, pp. 434-434
32. RAHEMTULLA A; SHAHINIAN A; KUNDIG T; ZINKERNAGEL R; MAK TW
    CD4 NEGATIVE MICE AS A MODEL FOR IMMUNODEFICIENCY
    Philosophical transactions-Royal Society of London. Biological sciences
    
    A. Rahemtulla et al., "CD4 NEGATIVE MICE AS A MODEL FOR IMMUNODEFICIENCY", Philosophical transactions-Royal Society of London. Biological sciences, 342(1299), 1993, pp. 57-58
33. PFEFFER K; MATSUYAMA T; KUNDIG TM; WAKEHAM A; KISHIHARA K; SHAHINIAN A; WIEGMANN K; OHASHI PS; KRONKE M; MAK TW
    MICE DEFICIENT FOR THE 55KD TUMOR-NECROSIS-FACTOR RECEPTOR ARE RESISTANT TO ENDOTOXIC-SHOCK, YET SUCCUMB TO L-MONOCYTOGENES INFECTION
    Cell
    
    K. Pfeffer et al., "MICE DEFICIENT FOR THE 55KD TUMOR-NECROSIS-FACTOR RECEPTOR ARE RESISTANT TO ENDOTOXIC-SHOCK, YET SUCCUMB TO L-MONOCYTOGENES INFECTION", Cell, 73(3), 1993, pp. 457-467
34. SHAHINIAN A; PFEFFER K; LEE KP; KUNDIG TM; KISHIHARA K; WAKEHAM A; KAWAI K; OHASHI PS; THOMPSON CB; MAK TW
    DIFFERENTIAL T-CELL COSTIMULATORY REQUIREMENTS IN CD28-DEFICIENT MICE
    Science
    
    A. Shahinian et al., "DIFFERENTIAL T-CELL COSTIMULATORY REQUIREMENTS IN CD28-DEFICIENT MICE", Science, 261(5121), 1993, pp. 609-612