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    1. Froger, N; Gardier, AM; Moratalla, R; Alberti, I; Lena, I; Boni, C; De Felipe, C; Rupniak, NMJ; Hunt, SP; Jacquot, C; Hamon, M; Lanfumey, L
      5-Hydroxytryptamine (5-HT)(1A) autoreceptor adaptive changes in substance P (Neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization

      JOURNAL OF NEUROSCIENCE
    2. Boyce, S; Smith, D; Carlson, E; Hewson, L; Rigby, M; O'Donnell, R; Harrison, T; Rupniak, NMJ
      Intra-amygdala injection of the substance P (NK1 receptor) antagonist L-760735 inhibits neonatal vocalisations in guinea-pigs

      NEUROPHARMACOLOGY
    3. Boyce, S; Rupniak, NMJ; Steventon, MJ; Iversen, SD
      Differential effects of D-1 and D-2 agonists in MPTP,treated primates: Functional implications for Parkinson's disease

      NEUROLOGY
    4. Harrison, T; Owens, AP; Williams, BJ; Swain, CJ; Williams, A; Carlson, EJ; Rycroft, W; Tattersall, FD; Cascieri, MA; Chicchi, GG; Sadowski, S; Rupniak, NMJ; Hargreaves, RJ
      An orally active, water-soluble neurokinin-1 receptor antagonist suitable for both intravenous and oral clinical administration

      JOURNAL OF MEDICINAL CHEMISTRY
    5. Cheeta, S; Tucci, S; Sandhu, J; Williams, AR; Rupniak, NMJ; File, SE
      Anxiolytic actions of the substance P (NK1) receptor antagonist L-760735 and the 5-HT1A agonist 8-OH-DPAT in the social interaction test in gerbils

      BRAIN RESEARCH
    6. Boyce, S; Webb, JK; Shepheard, SL; Russell, MGN; Hill, RG; Rupniak, NMJ
      Analgesic and toxic effects of ABT-594 resemble epibatidine and nicotine in rats

      PAIN
    7. Rupniak, NMJ; Carlson, EC; Harrison, T; Oates, B; Seward, E; Owen, S; de Felipe, C; Hunt, S; Wheeldon, A
      Pharmacological blockade or genetic deletion of substance P (NK1) receptors attenuates neonatal vocalisation in guinea-pigs and mice

      NEUROPHARMACOLOGY
    8. Hale, JJ; Mills, SG; MacCoss, M; Dorn, CP; Finke, PE; Budhu, RJ; Reamer, RA; Huskey, SEW; Luffer-Atlas, D; Dean, BJ; McGowan, EM; Feeney, WP; Chiu, SHL; Cascieri, MA; Chicchi, GG; Kurtz, MM; Sadowski, S; Ber, E; Tattersall, FD; Rupniak, NMJ; Williams, AR; Rycroft, W; Hargreaves, R; Metzger, JM; MacIntyre, DE
      Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs

      JOURNAL OF MEDICINAL CHEMISTRY
    9. Maubach, KA; Rupniak, NMJ; Kramer, MS; Hill, RG
      Novel strategies for pharmacotherapy of depression

      CURRENT OPINION IN CHEMICAL BIOLOGY
    10. Rupniak, NMJ; Laird, JMA; Boyce, S; Hill, RG
      Neurotrophic factors in peripheral nerve injury and regeneration

      NEUROTROPHIC FACTORS
    11. Swain, C; Rupniak, NMJ
      Progress in the development of neurokinin antagonists

      ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 34
    12. Boyce, S; Wyatt, A; Webb, JK; O'Donnell, R; Mason, G; Rigby, M; Sirinathsinghji, D; Hill, RG; Rupniak, NMJ
      Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn

      NEUROPHARMACOLOGY
    13. Boyce, S; Webb, JK; Carlson, E; Rupniak, NMJ; Hill, RG; Martin, JE
      Onset and progression of motor deficits in motor neuron degeneration (mnd)mice are unaltered by the glycine/NMDA receptor antagonist L-701,324 or the MAO-B inhibitor R(-)-deprenyl

      EXPERIMENTAL NEUROLOGY
    14. Smith, DW; Hewson, L; Fuller, P; Williams, AR; Wheeldon, A; Rupniak, NMJ
      The substance P antagonist L-760,735 inhibits stress-induced NK, receptor internalisation in the basolateral amygdala

      BRAIN RESEARCH
    15. Rupniak, NMJ; Kramer, MS
      Discovery of the anti-depressant and anti-emetic efficacy of substance P receptor (NK1) antagonists

      TRENDS IN PHARMACOLOGICAL SCIENCES
    16. KRAMER MS; CUTLER N; FEIGHNER J; SHRIVASTAVA R; CARMAN J; SRAMEK JJ; REINES SA; LIU GH; SNAVELY D; WYATTKNOWLES E; HALE JJ; MILLS SG; MACCOSS M; SWAIN CJ; HARRISON T; HILL RG; HEFTI F; SCOLNICK EM; CASCIERI MA; CHICCHI GG; SADOWSKI S; WILLIAMS AR; HEWSON L; SMITH D; CARLSON EJ; HARGREAVES RJ; RUPNIAK NMJ
      DISTINCT MECHANISM FOR ANTIDEPRESSANT ACTIVITY BY BLOCKADE OF CENTRALSUBSTANCE-P RECEPTORS

      Science
    17. Cumberbatch, MJ; Carlson, E; Wyatt, A; Boyce, S; Hill, RG; Rupniak, NMJ
      Reversal of behavioural and electrophysiological correlates of experimental peripheral neuropathy by the NK1 receptor antagonist GR205171 in rats

      NEUROPHARMACOLOGY
    18. CUMBERBATCH MJ; WYATT A; BOYCE S; HILL RG; RUPNIAK NMJ
      REVERSAL OF BEHAVIORAL AND ELECTROPHYSIOLOGICAL CORRELATES OF EXPERIMENTAL PERIPHERAL NEUROPATHY BY THE NK1 RECEPTOR ANTAGONIST GR-205171 IN RATS

      Neurology
    19. HALE JJ; MILLS SG; MACCOSS M; FINKE PE; CASCIERI MA; SADOWSKI S; BER E; CHICCHI GG; KURTZ M; METZGER J; EIERMANN G; TSOU NN; TATTERSALL FD; RUPNIAK NMJ; WILLIAMS AR; RYCROFT W; HARGREAVES R; MACINTYRE DE
      STRUCTURAL OPTIMIZATION AFFORDING ENYL-4-(3-OXO-1,2,4-TRIAZOL-5-YL)METHYLMORPHOLINE, A POTENT, ORALLY-ACTIVE, LONG-ACTING MORPHOLINE ACETALHUMAN NK-1 RECEPTOR ANTAGONIST

      Journal of medicinal chemistry
    20. RUPNIAK NMJ; BOYCE S; WEBB JK; WILLIAMS AR; CARLSON EJ; HILL RG; BORKOWSKI JA; HESS JF
      EFFECTS OF THE BRADYKININ B-1 RECEPTOR ANTAGONIST DES-ARG(9)[LEU(8)]BRADYKININ AND GENETIC DISRUPTION OF THE B-2 RECEPTOR ON NOCICEPTION INRATS AND MICE

      Pain
    21. PATEL S; FREEDMAN S; CHAPMAN KL; EMMS F; FLETCHER AE; KNOWLES M; MARWOOD R; MCALLISTER G; MYERS J; PATEL S; CURTIS N; KULAGOWSKI JJ; LEESON PD; RIDGILL M; GRAHAM M; MATHESON S; RATHBONE D; WATT AP; BRISTOW LJ; RUPNIAK NMJ; BASKIN E; LYNCH JJ; RAGAN CI
      BIOLOGICAL PROFILE OF L-745,870, A SELECTIVE ANTAGONIST WITH HIGH-AFFINITY FOR THE DOPAMINE-D4 RECEPTOR

      The Journal of pharmacology and experimental therapeutics
    22. RUPNIAK NMJ; TATTERSALL FD; WILLIAMS AR; RYCROFT W; CARLSON EJ; CASCIERI MA; SADOWSKI S; BER E; HALE JJ; MILLS SG; MACCOSS M; SEWARD E; HUSCROFT I; OWEN S; SWAIN CJ; HILL RG; HARGREAVES RJ
      IN-VITRO AND IN-VIVO PREDICTORS OF THE ANTIEMETIC ACTIVITY OF TACHYKININ NK1 RECEPTOR ANTAGONISTS

      European journal of pharmacology
    23. RUPNIAK NMJ; TATTERSALL FD; WILLIAMS AR; RYCROFT W; CARLSON EJ; CASCIERI MA; HALE JJ; MILLS SG; MACCOSS M; SEWARD E; HUSCROFT I; SWAIN CJ; HILL RG; HARGREAVES RJ
      PREDICTION OF THE ANTIEMETIC ACTIVITY OF NK1 RECEPTOR ANTAGONISTS IN FERRETS BY THEIR ABILITY TO INHIBIT GR73632-INDUCED FOOT TAPPING IN GERBILS

      British Journal of Pharmacology
    24. RUPNIAK NMJ; TYE SJ; FIELD MJ
      EFFECT OF THE ACETYLCHOLINESTERASE INHIBITOR E2020 IN TESTS OF SPATIAL AND VISUAL RECOGNITION MEMORY IN RHESUS-MONKEYS

      British Journal of Pharmacology
    25. RUPNIAK NMJ; TYE SJ; FIELD MJ
      ENHANCED PERFORMANCE OF SPATIAL AND VISUAL RECOGNITION MEMORY TASKS BY THE SELECTIVE ACETYLCHOLINESTERASE INHIBITOR E2020 IN RHESUS-MONKEYS

      Psychopharmacology
    26. RUPNIAK NMJ; CARLSON E; BOYCE S; WEBB JK; HILL RG
      ENANTIOSELECTIVE INHIBITION OF THE FORMALIN PAW LATE-PHASE BY THE NK1RECEPTOR ANTAGONIST L-733,060 IN GERBILS

      Pain
    27. WEBB JK; RUPNIAK NMJ; BOYCE S
      INHIBITION OF PENTAGASTRIN-INDUCED PRESSOR-RESPONSE IN CONSCIOUS RATSBY THE CCK-B RECEPTOR ANTAGONIST CI-988 AND CHLORDIAZEPOXIDE

      Regulatory peptides
    28. BOYCE S; RUPNIAK NMJ; CARLSON EJ; WEBB J; BORKOWSKI JA; HESS JF; STRADER CD; HILL RG
      NOCICEPTION AND INFLAMMATORY HYPERALGESIA IN B-2 BRADYKININ RECEPTOR KNOCKOUT MICE

      Immunopharmacology
    29. RUPNIAK NMJ; CARLSON E; BOYCE S; WEBB JK; HILL RG
      ENANTIOSELECTIVE INHIBITION OF THE FORMALIN PAW LATE-PHASE BY THE NK1RECEPTOR ANTAGONIST L-773,060 IN GERBILS

      British Journal of Pharmacology
    30. BOYCE S; RUPNIAK NMJ; CARLSON EJ; WEBB JK; BORKOWSKI JA; HESS JF; STRADER CD; HILL RG
      NOCICEPTION AND INFLAMMATORY HYPERALGESIA IN B-2 BRADYKININ RECEPTOR KNOCKOUT MICE

      British Journal of Pharmacology
    31. RUPNIAK NMJ; WEBB JK; WILLIAMS AR; CARLSON E; BOYCE S; HILL RG
      ANTINOCICEPTIVE ACTIVITY OF THE TACHYKININ NK1 RECEPTOR ANTAGONIST, CP-99,994, IN CONSCIOUS GERBILS

      British Journal of Pharmacology
    32. WEBB JK; BOYCE S; RUPNIAK NMJ
      CARDIOVASCULAR EFFECTS OF ANXIOGENIC AND ANXIOLYTIC AGENTS IN CONSCIOUS RATS

      British Journal of Pharmacology
    33. RUPNIAK NMJ; BOYCE S; JACKSON A; PEARCE D
      BEHAVIORS ELICITED BY INFUSION OF TACHYKININ RECEPTOR AGONISTS INTO MIDBRAIN DOPAMINE REGIONS IN RATS

      British Journal of Pharmacology
    34. DAWSON GR; RUPNIAK NMJ; IVERSEN SD; CURNOW R; TYE S; STANHOPE KJ; TRICKLEBANK MD
      LACK OF EFFECT OF CCKB RECEPTOR ANTAGONISTS IN ETHOLOGICAL AND CONDITIONED ANIMAL SCREENS FOR ANXIOLYTIC DRUGS

      Psychopharmacology
    35. BOYCE S; CHAN CC; GORDON R; LI CS; RODGER IW; WEBB JK; RUPNIAK NMJ; HILL RG
      L-745,337 - A SELECTIVE INHIBITOR OF CYCLOOXYGENASE-2 ELICITS ANTINOCICEPTION BUT NOT GASTRIC-ULCERATION IN RATS

      Neuropharmacology
    36. RUPNIAK NMJ; WILLIAMS AR
      DIFFERENTIAL INHIBITION OF FOOT TAPPING AND CHROMODACRYORRHOEA IN GERBILS BY CNS PENETRANT AND NON-PENETRANT TACHYKININ NK1 RECEPTOR ANTAGONISTS

      European journal of pharmacology
    37. RUPNIAK NMJ; JACKSON A
      NONSPECIFIC INHIBITION OF DOPAMINE-RECEPTOR AGONIST-INDUCED BEHAVIOR BY THE TACHYKININ NK1 RECEPTOR ANTAGONIST CP-99,994 IN GUINEA-PIGS

      European journal of pharmacology
    38. RUPNIAK NMJ; PATEL S; MARWOOD R; WEBB J; TRAYNOR JR; ELLIOTT J; FREEDMAN SB; FLETCHER SR; HILL RG
      ANTINOCICEPTIVE AND TOXIC EFFECTS OF (-EPIBATIDINE OXALATE ATTRIBUTABLE TO NICOTINIC AGONIST ACTIVITY())

      British Journal of Pharmacology
    39. RUPNIAK NMJ; SCHAFFER L; SIEGL P; IVERSEN SD
      FAILURE OF INTRAVENOUS PENTAGASTRIN CHALLENGE TO INDUCE PANIC-LIKE EFFECTS IN RHESUS-MONKEYS

      Neuropeptides
    40. RUPNIAK NMJ; IVERSEN SD
      COGNITIVE IMPAIRMENT IN SCHIZOPHRENIA - HOW EXPERIMENTAL-MODELS USINGNONHUMAN-PRIMATES MAY ASSIST IMPROVED DRUG-THERAPY FOR NEGATIVE SYMPTOMS

      Neuropsychologia
    41. RUPNIAK NMJ; BOYCE S; WILLIAMS AR; COOK G; LONGMORE J; SEABROOK GR; CAESER M; IVERSEN SD; HILL RG
      ANTINOCICEPTIVE ACTIVITY OF NK(1) RECEPTOR ANTAGONISTS - NONSPECIFIC EFFECTS OF RACEMIC RP67580

      British Journal of Pharmacology


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Documento generato il 25/05/20 alle ore 04:49:33