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    1. Pessayre, D; Berson, A; Fromenty, B; Mansouri, A
      Mitochondria in steatohepatitis

      SEMINARS IN LIVER DISEASE
    2. Haouzi, D; Lekehal, M; Tinel, M; Vadrot, N; Caussanel, L; Letteron, P; Moreau, A; Feldmann, G; Fau, D; Pessayre, D
      Prolonged, but not acute, glutathione depletion promotes Fas-mediated mitochondrial permeability transition and apoptosis in mice

      HEPATOLOGY
    3. Berson, A; Fau, D; Fornacciari, R; Degove-Goddard, P; Sutton, A; Descatoire, V; Haouzi, D; Letteron, P; Moreau, A; Feldmann, G; Pessayre, D
      Mechanisms for experimental buprenorphine hepatotoxicity: major role of mitochondrial dysfunction versus metabolic activation

      JOURNAL OF HEPATOLOGY
    4. Berson, A; Gervais, A; Cazals, D; Boyer, N; Durand, F; Bernuau, J; Marcellin, P; Degott, C; Valla, D; Pessayre, D
      Hepatitis after intravenous buprenorphine misuse in heroin addicts

      JOURNAL OF HEPATOLOGY
    5. Berson, A; Descatoire, V; Sutton, A; Fau, D; Maulny, B; Vadrot, N; Feldmann, G; Berthon, B; Tordjmann, T; Pessayre, D
      Toxicity of alpidem, a peripheral benzodiazepine receptor ligand, but not zolpidem, in rat hepatocytes: Role of mitochondrial permeability transitionand metabolic activation

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    6. Mansouri, A; Demeilliers, C; Amsellem, S; Pessayre, D; Fromenty, B
      Acute ethanol administration oxidatively damages and depletes mitochondrial DNA in mouse liver, brain, heart, and skeletal muscles: Protective effects of antioxidants

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    7. Gaou, I; Malliti, M; Guimont, MC; Letteron, P; Demeilliers, C; Peytavin, G; Degott, C; Pessayre, D; Fromenty, B
      Effect of stavudine on mitochondrial genome and fatty acid oxidation in lean and obese mice

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    8. Degoul, F; Sutton, A; Mansouri, A; Cepanec, C; Degott, C; Fromenty, B; Beaugrand, M; Valla, D; Pessayre, D
      Homozygosity for alanine in the mitochondrial targeting sequence of superoxide dismutase and risk for severe alcoholic liver disease

      GASTROENTEROLOGY
    9. Fromenty, B; Mansouri, A; Degoul, F; Demeilliers, C; Gaou, I; Pessayre, D
      Ageing, alcohol and mitochondria

      GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE
    10. Haouzi, D; Lekehal, M; Moreau, A; Moulis, C; Feldmann, G; Robin, MA; Letteron, P; Fau, D; Pessayre, D
      Cytochrome P450-generated reactive metabolites cause mitochondrial permeability transition, caspase activation, and apoptosis in rat hepatocytes

      HEPATOLOGY
    11. Feldmann, G; Haouzi, D; Moreau, A; Durand-Schneider, AM; Bringuier, A; Berson, A; Mansouri, A; Fau, D; Pessayre, D
      Opening of the mitochondrial permeability transition pore causes matrix expansion and outer membrane rupture in Fas-mediated hepatic apoptosis in mice

      HEPATOLOGY
    12. Pessayre, D; Feldmann, G; Haouzi, D; Fau, D; Moreau, A; Neuman, M
      Hepatocyte apoptosis triggered by natural substances (cytokines, other endogenous molecules and foreign toxins)

      APOPTOSIS AND ITS MODULATION BY DRUGS
    13. De Berardinis, V; Moulis, C; Maurice, M; Beaune, P; Pessayre, D; Pompon, D; Loeper, J
      Human microsomal epoxide hydrolase is the target of germander-induced autoantibodies on the surface of human hepatocytes

      MOLECULAR PHARMACOLOGY
    14. Robin, MA; Descatoire, V; Le Roy, M; Berson, A; Lebreton, FP; Maratrat, M; Ballet, F; Loeper, J; Pessayre, D
      Vesicular transport of newly synthesized cytochromes P4501A to the outsideof rat hepatocyte plasma membranes

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    15. Pessayre, D; Mansouri, A; Haouzi, D; Fromenty, B
      Hepatotoxicity due to mitochondrial dysfunction

      CELL BIOLOGY AND TOXICOLOGY
    16. Pessayre, D; Haouzi, D; Fau, D; Robin, MA; Mansouri, A; Person, A
      Withdrawal of life support, altruistic suicide, fratricidal killing and euthanasia by lymphocytes: different forms of drug-induced hepatic apoptosis

      JOURNAL OF HEPATOLOGY
    17. Tinel, M; Elkahwaji, J; Robin, MA; Fardel, N; Descatoire, V; Haouzi, D; Berson, A; Pessayre, D
      Interleukin-2 overexpresses c-myc and down-regulates cytochrome P-450 in rat hepatocytes

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    18. Deltenre, P; Berson, A; Marcellin, P; Degott, C; Biour, M; Pessayre, D
      Mesalazine (5-aminosalicylic acid) induced chronic hepatitis

      GUT
    19. Mansouri, A; Gaou, I; De Kerguenec, C; Amsellem, S; Haouzi, D; Berson, A; Moreau, A; Feldmann, G; Letteron, P; Pessayre, D; Fromenty, B
      An alcoholic binge causes massive degradation of hepatic mitochondrial DNAin mice

      GASTROENTEROLOGY
    20. Elkahwaji, J; Robin, MA; Berson, A; Tinel, M; Letteron, P; Labbe, G; Beaune, P; Elias, D; Rougier, P; Escudier, B; Duvillard, P; Pessayre, D
      Decrease in hepatic cytochrome P450 after interleukin-2 Immunotherapy

      BIOCHEMICAL PHARMACOLOGY
    21. DURAND F; BERNUAU J; PESSAYRE D
      HEPATOTOXICITY OF ANTITUBERCULAR AGENTS - IMPLICATIONS FOR SCREENING

      Gastroenterologie clinique et biologique
    22. BERSON A; FROMENTY B; LETTERON P; PESSAYRE D
      ROLE OF MITOCHONDRIA IN DRUG-INDUCED HEPATOTOXICITY

      Gastroenterologie clinique et biologique
    23. Dansette, PM; Bonierbale, E; Minoletti, C; Beaune, PH; Pessayre, D; Mansuy, D
      Drug-induced immunotoxicity

      EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
    24. FROMENTY B; MANSOURI A; PESSAYRE D
      PREMATURE OXIDATIVE DAMAGE TO HEPATIC MITOCHONDRIAL-DNA IN ALCOHOLIC PATIENTS WITH MICROVESICULAR STEATOSIS

      Alcoholism, clinical and experimental research
    25. BERSON A; DEBECO V; LETTERON P; ROBIN MA; MOREAU C; ELKAHWAJI J; VERTHIER N; FELDMANN G; FROMENTY B; PESSAYRE D
      STEATOHEPATITIS-INDUCING DRUGS CAUSE MITOCHONDRIAL DYSFUNCTION AND LIPID-PEROXIDATION IN RAT HEPATOCYTES

      Gastroenterology
    26. FAU D; LEKEHAL M; FARRELL G; MOREAU A; MOULLS C; FELDMAN G; PESSAYRE D
      APOPTOSIS IN ISOLATED RAT HEPATOCYTES IS TRIGGERED BY THE DITERPENOIDS OF THE HERBAL MEDICINE GERMANDER AND ENHANCED BY FEEDING A SULFUR AMINO-ACID (SAA) DEFICIENT DIET

      The FASEB journal
    27. LEVY P; LETTERON P; PAYE F; MOLAS G; GUIMONT MC; PESSAYRE D; BERNADES P; ROZE C
      IN-VIVO ASSESSMENT OF LIPID-PEROXIDATION IN EXPERIMENTAL EDEMATOUS AND NECROTIZING RAT PANCREATITIS

      Pancreas
    28. BERNUAU J; DURAND F; PESSAYRE D
      KETOCONAZOLE-INDUCED HEPATOTOXICITY

      Hepatology
    29. LETTERON P; BRAHIMIBOUROUINA N; ROBIN MA; MOREAU A; FELDMANN G; PESSAYRE D
      GLUCOCORTICOIDS INHIBIT MITOCHONDRIAL MATRIX ACYL-COA DEHYDROGENASES AND FATTY-ACID BETA-OXIDATION

      American journal of physiology: Gastrointestinal and liver physiology
    30. MALKA D; PHAM BN; COURVALIN JC; CORBIC M; PESSAYRE D; ERLINGER S
      ACUTE HEPATITIS CAUSED BY ALVERINE ASSOCIATED WITH ANTI-LAMIN-A AND ANTI-LAMIN-C AUTOANTIBODIES

      Journal of hepatology
    31. MANSOURI A; FROMENTY B; BERSON A; ROBIN MA; GRIMBERT S; BEAUGRAND M; ERLINGER S; PESSAYRE D
      MULTIPLE HEPATIC MITOCHONDRIAL-DNA DELETIONS SUGGEST PREMATURE OXIDATIVE AGING IN ALCOHOLIC PATIENTS

      Journal of hepatology
    32. FROMENTY B; PESSAYRE D
      IMPAIRED MITOCHONDRIAL-FUNCTION IN MICROVESICULAR STEATOSIS - EFFECTSOF DRUGS, ETHANOL, HORMONES AND CYTOKINES

      Journal of hepatology
    33. FAU D; LEKEHAL M; FARRELL G; MOREAU A; MOULIS C; FELDMANN G; HAOUZI D; PESSAYRE D
      DITERPENOIDS FROM GERMANDER, AN HERBAL MEDICINE, INDUCE APOPTOSIS IN ISOLATED RAT HEPATOCYTES

      Gastroenterology
    34. MANSOURI A; GAOU I; FROMENTY B; BERSON A; LETTERON P; DEGOTT C; ERLINGER S; PESSAYRE D
      PREMATURE OXIDATIVE AGING OF HEPATIC MITOCHONDRIAL-DNA IN WILSONS-DISEASE

      Gastroenterology
    35. FELDMANN G; MOREAU A; FAU D; LEKEHAL M; FARREL G; PESSAYRE D
      APOPTOSIS IS THE FORM OF CELL-DEATH INDUCED BY GERMANDER IN RAT HEPATOCYTES

      Molecular biology of the cell
    36. FROMENTY B; MANSOURI A; BONNEFONT JP; COURTOIS F; MUNNICH A; RABIER D; PESSAYRE D
      MOST CASES OF MEDIUM-CHAIN ACYL-COA DEHYDROGENASE-DEFICIENCY ESCAPE DETECTION IN FRANCE

      Human genetics
    37. LEKEHAL M; PESSAYRE D; LEREAU JM; MOULIS C; FOURASTE I; FAU D
      HEPATOTOXICITY OF THE HERBAL MEDICINE GERMANDER - METABOLIC-ACTIVATION OF ITS FURANO DITERPENOIDS BY CYTOCHROME-P450 3A DEPLETES CYTOSKELETON-ASSOCIATED PROTEIN THIOLS AND FORMS PLASMA-MEMBRANE BLEBS IN RAT HEPATOCYTES

      Hepatology
    38. MANSOURI A; FROMENTY B; DURAND F; DEGOTT C; BERNUAU J; PESSAYRE D
      ASSESSMENT OF THE PREVALENCE OF GENETIC METABOLIC DEFECTS IN ACUTE FATTY LIVER OF PREGNANCY

      Journal of hepatology
    39. LETTERON P; FROMENTY B; TERRIS B; DEGOTT C; PESSAYRE D
      ACUTE AND CHRONIC HEPATIC STEATOSIS LEAD TO IN-VIVO LIPID-PEROXIDATION IN MICE

      Journal of hepatology
    40. DURAND F; JEBRAK G; PESSAYRE D; FOURNIER M; BERNUAU J
      HEPATOTOXICITY OF ANTITUBERCULAR TREATMENTS - RATIONALE FOR MONITORING LIVER STATUS

      Drug safety
    41. ROBIN MA; MARATRAT M; LEROY M; LEBRETON FP; BONIERBALE E; DANSETTE P; BALLET F; MANSUY D; PESSAYRE D
      ANTIGENIC TARGETS IN TIENILIC ACID HEPATITIS - BOTH CYTOCHROME-P450 2C11 AND 2C11-TIENILIC ACID ADDUCTS ARE TRANSPORTED TO THE PLASMA-MEMBRANE OF RAT HEPATOCYTES AND RECOGNIZED BY HUMAN SERA

      The Journal of clinical investigation
    42. BERSON A; RENAULT S; LETTERON P; ROBIN MA; FROMENTY B; FAU D; LEBOT MA; RICHE C; DURANDSCHNEIDER AM; FELDMANN G; PESSAYRE D
      UNCOUPLING OF RAT AND HUMAN MITOCHONDRIA - A POSSIBLE EXPLANATION FORTACRINE-INDUCED LIVER DYSFUNCTION

      Gastroenterology
    43. FISCH C; ROBIN MA; LETTERON P; FROMENTY B; BERSON A; RENAULT S; CHACHATY C; PESSAYRE D
      CELL-GENERATED NITRIC-OXIDE INACTIVATES RAT HEPATOCYTE MITOCHONDRIA IN-VITRO BUT REACTS WITH HEMOGLOBIN IN-VIVO

      Gastroenterology
    44. FAU D; LEKEHAL M; MOULIS C; PESSAYRE D
      ROLE OF GLUTATHIONE IN THE PREVENTION AGAINST GERMANDER HEPATOTOXICITY - INCREASED CYTOTOXICITY IN HEPATOCYTES ISOLATED FROM RATS FED A SULFUR AMINO-ACID (SAA) DEFICIENT DIET

      The FASEB journal
    45. PESSAYRE D
      MECHANISM OF DRUG-INDUCED HEPATITIS - SEQ UENCE OF THE SUPERPOSITION OF 2 PHOBIC SYSTEMS

      Gastroenterologie clinique et biologique
    46. DURAND F; BERNUAU J; PESSAYRE D; SAMUEL D; BELAICHE J; DEGOTT C; BISMUTH H; BELGHITI J; ERLINGER S; RUEFF B; BENHAMOU JP
      DELETERIOUS INFLUENCE OF PYRAZINAMIDE ON THE OUTCOME OF PATIENTS WITHFULMINANT OR SUBFULMINANT LIVER-FAILURE DURING ANTITUBERCULOUS TREATMENT INCLUDING ISONIAZID

      Hepatology
    47. GRIMBERT S; FISCH C; DESCHAMPS D; BERSON A; FROMENTY B; FELDMANN G; PESSAYRE D
      EFFECTS OF FEMALE SEX-HORMONES ON MITOCHONDRIA - POSSIBLE ROLE IN ACUTE FATTY LIVER OF PREGNANCY

      American journal of physiology: Gastrointestinal and liver physiology
    48. PESSAYRE D
      ROLE OF REACTIVE METABOLITES IN DRUG-INDUCED HEPATITIS

      Journal of hepatology
    49. FROMENTY B; PESSAYRE D
      INHIBITION OF MITOCHONDRIAL BETA-OXIDATION AS A MECHANISM OF HEPATOTOXICITY

      Pharmacology & therapeutics
    50. DURAND F; PESSAYRE D; FOURNIER M; BELGHITI J; ERLINGER S; BERNUAU J
      ANTITUBERCULOUS THERAPY AND ACUTE LIVER-FAILURE

      Lancet
    51. TINEL M; ROBIN MA; DOOSTZADEH J; MARATRAT M; BALLET F; FARDEL N; ELKAHWAJI J; BEAUNE P; DAUJAT M; LABBE G; PESSAYRE D
      THE INTERLEUKIN-2 RECEPTOR DOWN-REGULATES THE EXPRESSION OF CYTOCHROME-P450 IN CULTURED RAT HEPATOCYTES

      Gastroenterology
    52. ROBIN MA; MARATRAT M; LOEPER J; DURANDSCHNEIDER AM; TINEL M; BALLET F; BEAUNE P; FELDMANN G; PESSAYRE D
      CYTOCHROME P4502B FOLLOWS A VESICULAR ROUTE TO THE PLASMA-MEMBRANE INCULTURED RAT HEPATOCYTES

      Gastroenterology
    53. FROMENTY B; GRIMBERT S; MANSOURI A; BEAUGRAND M; ERLINGER S; ROTIG A; PESSAYRE D
      HEPATIC MITOCHONDRIAL-DNA DELETION IN ALCOHOLICS - ASSOCIATION WITH MICROVESICULAR STEATOSIS

      Gastroenterology
    54. DESCHAMPS D; DEBECO V; FISCH C; FROMENTY B; GUILLOUZO A; PESSAYRE D
      INHIBITION BY PERHEXILINE OF OXIDATIVE-PHOSPHORYLATION AND THE BETA-OXIDATION OF FATTY-ACIDS - POSSIBLE ROLE IN PSEUDOALCOHOLIC LIVER-LESIONS

      Hepatology
    55. FROMENTY B; GRIMBERT S; MANSOURI A; BEAUGRAND M; ROTIG A; PESSAYRE D
      MITOCHONDRIAL-DNA DELETION IN ALCOHOL-INDUCED MICROVESICULAR STEATOSIS

      Hepatology
    56. ROBIN MA; MARATRAT M; LOEPER J; DURANDSCHNEIDER AM; TINEL M; BALLET F; BEAUNE PH; FELDMANN G; PESSAYRE D
      CYTOCHROME-P-450 FOLLOWS A MICROTUBULE-DEPENDENT VESICULAR ROUTE TO THE PLASMA-MEMBRANE

      Hepatology
    57. TINEL M; ROBIN MA; DOOSTZADEH J; ELKAHWAJI J; BEAUNE PH; PESSAYRE D
      HUMAN RECOMBINANT INTERLEUKIN-2 (RHIL-2) DECREASES THE EXPRESSION OF CYTOCHROMES-P-450 (P-450) IN CULTURED RAT HEPATOCYTES

      Hepatology
    58. HORSMANS Y; LANNES D; PESSAYRE D; LARREY D
      POSSIBLE ASSOCIATION BETWEEN POOR METABOLISM OF MEPHENYTOIN AND HEPATOTOXICITY CAUSED BY ATRIUM(R), A FIXED COMBINATION PREPARATION CONTAINING PHENOBARBITAL, FEBARBAMATE AND DIFEBARBAMATE

      Journal of hepatology
    59. BERSON A; FRENEAUX E; LARREY D; LEPAGE V; DOUAY C; MALLET C; FROMENTRY B; BENHAMOU JP; PESSAYRE D
      POSSIBLE ROLE OF HLA IN HEPATOTOXICITY - AN EXPLORATORY-STUDY IN 71 PATIENTS WITH DRUG-INDUCED IDIOSYNCRATIC HEPATITIS

      Journal of hepatology
    60. GRIMBERT S; PESSAYRE D; DEGOTT C; BENHAMOU JP
      ACUTE HEPATITIS INDUCED BY HMG-COA REDUCTASE INHIBITOR, LOVASTATIN

      Digestive diseases and sciences
    61. BOURDI M; TINEL M; BEAUNE PH; PESSAYRE D
      INTERACTIONS OF DIHYDRALAZINE WITH CYTOCHROMES-P4501A - A POSSIBLE EXPLANATION FOR THE APPEARANCE OF ANTI-CYTOCHROME-P4501A2 AUTOANTIBODIES

      Molecular pharmacology
    62. BERSON A; SCHMETS L; FISCH C; FAU D; WOLF C; FROMENTY B; DESCHAMPS D; PESSAYRE D
      INHIBITION BY NILUTAMIDE OF THE MITOCHONDRIAL RESPIRATORY-CHAIN AND ATP FORMATION - POSSIBLE CONTRIBUTION TO THE ADVERSE-EFFECTS OF THIS ANTIANDROGEN

      The Journal of pharmacology and experimental therapeutics
    63. FAU D; EUGENE D; BERSON A; LETTERON P; FROMENTY B; FISCH C; PESSAYRE D
      TOXICITY OF THE ANTIANDROGEN FLUTAMIDE IN ISOLATED RAT HEPATOCYTES

      The Journal of pharmacology and experimental therapeutics
    64. THAL C; ELKAHWAJI J; LOEPER J; TINEL M; DOOSTZADEH J; LABBE G; LECLAIRE J; BEAUNE P; PESSAYRE D
      ADMINISTRATION OF HIGH-DOSES OF HUMAN RECOMBINANT INTERLEUKIN-2 DECREASES THE EXPRESSION OF SEVERAL CYTOCHROMES P-450 IN THE RAT

      The Journal of pharmacology and experimental therapeutics
    65. LEVY P; LETTERON P; PAYE F; MOLAS G; GUIMONT MC; PESSAYRE D; BERNADES P; ROZE C
      LIPID-PEROXIDATION IN DIFFERENT EXPERIMENTAL-MODELS OF ACUTE-PANCREATITIS (AP) - AN IN-VIVO ASSESSMENT

      Gastroenterology
    66. LOEPER J; DESCATOIRE V; LETTERON P; MOULIS C; DEGOTT C; DANSETTE P; FAU D; PESSAYRE D
      HEPATOTOXICITY OF GERMANDER IN MICE

      Gastroenterology
    67. BERSON A; WOLF C; CHACHATY C; FAU D; PESSAYRE D
      INTEREST OF ESR IN DETERMINING THE MECHANISMS OF DRUG TOXICITY - APPLICATION TO THE ANTIANDROGEN NILUTAMIDE

      Journal de chimie physique et de physico-chimie biologique
    68. PESSAYRE D
      MECHANISMS OF DRUG-INDUCED LIVER-LESIONS

      Gastroenterologie clinique et biologique
    69. FRENEAUX E; PESSAYRE D
      DRUG-INDUCED STEATOSIS, PHOSPHOLIPIDOSIS AND ALCOHOL-LIKE LIVER-INJURY

      Gastroenterologie clinique et biologique
    70. GRIMBERT S; FROMENTY B; FISCH C; LETTERON P; BERSON A; DURANDSCHNEIDER AM; FELDMANN G; PESSAYRE D
      DECREASED MITOCHONDRIAL OXIDATION OF FATTY-ACIDS IN PREGNANT MICE - POSSIBLE RELEVANCE TO DEVELOPMENT OF ACUTE FATTY LIVER OF PREGNANCY

      Hepatology
    71. PESSAYRE D
      CYTOCHROMES P450 AND FORMATION OF REACTIV E METABOLITES - ROLE IN DRUG-INDUCED HEPATOTOXICITY

      Therapie
    72. BERSON A; WOLF C; CHACHATY C; FISCH C; FAU D; EUGENE D; LOEPER J; GAUTHIER JC; BEAUNE P; POMPON D; MAUREL P; PESSAYRE D
      METABOLIC-ACTIVATION OF THE NITROAROMATIC ANTIANDROGEN FLUTAMIDE BY RAT AND HUMAN CYTOCHROMES-P-450, INCLUDING FORMS BELONGING TO THE 3A AND 1A SUBFAMILIES

      The Journal of pharmacology and experimental therapeutics
    73. FROMENTY B; LETTERON P; FISCH C; BERSON A; DESCHAMPS D; PESSAYRE D
      EVALUATION OF HUMAN BLOOD-LYMPHOCYTES AS A MODEL TO STUDY THE EFFECTSOF DRUGS ON HUMAN MITOCHONDRIA - EFFECTS OF LOW CONCENTRATIONS OF AMIODARONE ON FATTY-ACID OXIDATION, ATP LEVELS AND CELL-SURVIVAL

      Biochemical pharmacology


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Documento generato il 12/08/20 alle ore 16:49:57