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    1. Hirai, H; Nakajima, S; Miyauchi, A; Nishimura, K; Shimizu, N; Shima, M; Michigami, T; Ozono, K; Okada, S
      A novel activating mutation (C129S) in the calcium-sensing receptor gene in a Japanese family with autosomal dominant hypocalcemia

      JOURNAL OF HUMAN GENETICS
    2. Hatakeyama, S; Okano, T; Maeyama, J; Esumi, T; Hiyamizu, H; Iwabuchi, Y; Nakagawa, K; Ozono, K; Kawase, A; Kubodera, N
      Synthesis and evaluation of A-ring diastereomers of 1 alpha,25-dihydroxy-22-0xavitamin D-3 (OCT)

      BIOORGANIC & MEDICINAL CHEMISTRY
    3. Kubota, T; Yamamoto, T; Ozono, K; Shimotsuji, T
      Hyperintensity of posterior pituitary on MR T1WI in a boy with central diabetes insipidus caused by missense mutation of neurophysin II gene

      ENDOCRINE JOURNAL
    4. Yamamoto, T; Ozono, K; Miyauchi, A; Kasayama, S; Kojima, Y; Shima, M; Okada, S
      Role of advanced glycation end products in adynamic bone disease in patients with diabetic nephropathy

      AMERICAN JOURNAL OF KIDNEY DISEASES
    5. Matsui, Y; Nakata, K; Araki, N; Ozono, K; Fujita, Y; Tsumaki, N; Kawabata, H; Yasui, N; Sekiguchi, K; Yoshikawa, H
      Alternative splicing of fibronectin transcripts in osteochondrogenic tumors

      ANTICANCER RESEARCH
    6. Matsui, Y; Yasui, N; Ozono, K; Yamagata, M; Kawabata, H; Yoshikawa, H
      Loss of the SEDL gene product (Sedlin) causes X-linked spondyloepiphyseal dysplasia tarda: Identification of a molecular defect in a Japanese family

      AMERICAN JOURNAL OF MEDICAL GENETICS
    7. Ishizuka, S; Miura, D; Ozono, K; Saito, M; Eguchi, H; Chokki, M; Norman, AW
      (23S)- and (23R)-25-dehydro-1 alpha-hydroxyvitamin D-3-26,23-lactone function as antagonists of vitamin D receptor-mediated genomic actions of 1 alpha,25-dihydroxyvitamin D-3

      STEROIDS
    8. Nakagawa, K; Sowa, Y; Kurobe, M; Ozono, K; Siu-Caldera, ML; Reddy, GS; Uskokovic, MR; Okano, T
      Differential activities of 1 alpha,25-dihydroxy-16-ene-vitamin D-3 analogsand their 3-epimers on human promyelocytic leukemia (HL-60) cell differentiation and apoptosis

      STEROIDS
    9. Ozono, K; Obara, M; Usui, A; Sunakawa, H
      High-speed ablation etching of GaN semiconductor using femtosecond laser

      OPTICS COMMUNICATIONS
    10. Yanagihara, I; Inui, K; Yanagihara, K; Park, YD; Tanaka, J; Ozono, K; Okada, S; Kurabashi, H
      Fluorescence in situ hybridization analysis of peripheral blood cells in Pearson marrow-pancreas syndrome

      JOURNAL OF PEDIATRICS
    11. Michigami, T; Yamato, H; Suzuki, H; Nagai-Itagaki, Y; Sato, K; Ozono, K
      Conflicting actions of parathyroid hormone-related protein and serum calcium as regulators of 25-hydroxyvitamin D-3-1 alpha-hydroxylase expression ina nude rat model of humoral hypercalcemia of malignancy

      JOURNAL OF ENDOCRINOLOGY
    12. Yamagata, M; Kimoto, A; Michigami, T; Nakayama, M; Ozono, K
      Hydroxylases involved in vitamin D metabolism are differentially expressedin murine embryonic kidney: Application of whole mount in situ hybridization

      ENDOCRINOLOGY
    13. Ishizuka, S; Miura, D; Ozono, K; Chokki, M; Mimura, H; Norman, AW
      Antagonistic actions in vivo of (23S)-25-dehydro-1 alpha-hydroxyvitamin D-3,26,23-lactone on calcium metabolism induced by 1 alpha,25-dihydroxyvitamin D-3

      ENDOCRINOLOGY
    14. Michigami, T; Ihara-Watanabe, M; Yamazaki, M; Ozono, K
      Receptor activator of nuclear factor kappa B ligand (RANKL) is a key molecule of osteoclast formation for bone metastasis in a newly developed model of human neuroblastoma

      CANCER RESEARCH
    15. Matsui, Y; Yasui, N; Kawabata, H; Ozono, K; Nakata, K; Mizushima, T; Tsumaki, N; Kataoka, E; Fujita, Y; Ochi, T
      A novel type X collagen gene mutation (G595R) associated with Schmid-type metaphyseal chondrodysplasia

      JOURNAL OF HUMAN GENETICS
    16. Kubodera, N; Okano, T; Nakagawa, K; Ozono, K; Mikami, K
      Biological activities of 19-nor-1 alpha,25-dihydroxyvitamin D3 analogs singly dehydroxylated at the C-1 or C-3 position of the A-ring

      CURRENT PHARMACEUTICAL DESIGN
    17. Okano, T; Nakagawa, K; Kubodera, N; Ozono, K; Isaka, A; Osawa, A; Terada, M; Mikami, K
      Catalytic asymmetric syntheses and biological activities of singly dehydroxylated 19-nor-1 alpha,25-dihydroxyvitamin D-3 A-ring analogs in cancer cell differentiation and apoptosis

      CHEMISTRY & BIOLOGY
    18. Tsugawa, N; Nakagawa, K; Kurobe, M; Ono, Y; Kubodera, N; Ozono, K; Okano, T
      In vitro biological activities of a series of 2 beta-substituted analoguesof 1 alpha,25-dihydroxyvitamin D-3

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    19. Yanagihara, I; Yamagata, M; Sakai, N; Shukunami, C; Kurahashi, H; Yamazaki, M; Michigami, T; Hiraki, Y; Ozono, K
      Genomic organization of the human chondromodulin-1 gene containing a promoter region that confers the expression of reporter gene in chondrogenic ATDC5 cells

      JOURNAL OF BONE AND MINERAL RESEARCH
    20. Mochizuki, H; Saito, M; Michigami, T; Ohashi, H; Koda, N; Yamaguchi, S; Ozono, K
      Severe hypercalcaemia and respiratory insufficiency associated with infantile hypophosphatasia caused by two novel mutations of the tissue-nonspecific alkaline phosphatase gene

      EUROPEAN JOURNAL OF PEDIATRICS
    21. Nakajima, S; Yamagata, M; Sakai, N; Ozono, K
      Effect of cyclic adenosine 3 ',5 '-monophosphate and protein kinase A on ligand-dependent transactivation via the vitamin D receptor

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    22. Muller, HL; Yamazaki, M; Michigami, T; Kageyama, T; Schonau, E; Schneider, P; Ozono, K
      Asp(361)Val mutant of alkaline phosphatase found in patients with dominantly inherited hypophosphatasia inhibits the activity of the wild-type enzyme

      JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
    23. Nakagawa, K; Kurobe, M; Ozono, K; Konno, K; Fujishima, T; Takayama, H; Okano, T
      Novel ring A stereoisomers of 2-methyl-1 alpha,25-dihydroxyvitamin D-3 and2-methyl-20-epi-1 alpha,25-dihydroxyvitamin D-3: Transactivation of targetgenes and modulation of differentiation in human promyelocytic leukemia (HL-60) cells

      BIOCHEMICAL PHARMACOLOGY
    24. Ishizuka, S; Miura, D; Eguchi, H; Ozono, K; Chokki, M; Kamimura, T; Norman, AW
      Antagonistic action of novel 1 alpha,25-dihydroxyvitamin D-3-26,23-lactoneanalogs on 25-hydroxyvitamin-D-3-24-hydroxylase gene expression induced by1 alpha,25-dihydroxyvitamin D-3 in human promyelocytic leukemia (HL-60) cells

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    25. Tsugawa, N; Nakagawa, K; Kawamoto, Y; Tachibana, Y; Hayashi, T; Ozono, K; Okano, T
      Biological activity profiles of 1 alpha,25-dihydroxyvitamin D-2, D-3, D-4,D-7 and 24-epi-1 alpha,25-dihydroxyvitamin D-2

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    26. Nishimura, G; Hong, HS; Kawame, H; Sato, S; Cai, G; Ozono, K
      A mild variant of Desbuquois dysplasia

      EUROPEAN JOURNAL OF PEDIATRICS
    27. Michigami, T; Suga, A; Yamazaki, M; Shimizu, C; Cai, GM; Okada, S; Ozono, K
      Identification of amino acid sequence in the hinge region of human vitaminD receptor that transfers a cytosolic protein to the nucleus

      JOURNAL OF BIOLOGICAL CHEMISTRY
    28. Ozono, K; Saito, M; Miura, D; Michigami, T; Nakajima, S; Ishizuka, S
      Analysis of the molecular mechanism for the antagonistic action of a novel1 alpha,25-dihydroxyvitamin D-3 analogue toward vitamin D receptor function

      JOURNAL OF BIOLOGICAL CHEMISTRY
    29. Miura, D; Manabe, K; Ozono, K; Saito, M; Gao, QZ; Norman, AW; Ishizuka, S
      Antagonistic action of novel 1 alpha,25-dihydroxyvitamin D-3-26,23-lactoneanalogs on differentiation of human leukemia cells (HL-60) induced by 1 alpha,25-dihydroxyvitamin D-3

      JOURNAL OF BIOLOGICAL CHEMISTRY
    30. OZONO K; YAMAGATA M; OHYAMA Y; NAKAJIMA S
      DIRECT REPEAT 3-TYPE ELEMENT LACKING THE ABILITY TO BIND TO THE VITAMIN-D-RECEPTOR ENHANCES THE FUNCTION OF A VITAMIN-D-RESPONSIVE ELEMENT

      Journal of steroid biochemistry and molecular biology
    31. Okano, T; Nakagawa, K; Tsugawa, N; Ozono, K; Kubodera, N; Osawa, A; Terada, M; Mikami, K
      Singly dehydroxylated a-ring analogues of 19-nor-1 alpha-25-dihydroxyvitamin D-3 and 19-nor-22-oxa-1 alpha,25-dihydroxyvitamin D-3: Novel vitamin D-3analogues with potent transcriptional activity but extremely low affinity for vitamin D receptor

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    32. NAKAJIMA S; YAMAGATA M; SAKAI N; OZONO K
      CHARACTERIZATION OF THE ACTIVATION FUNCTION-2 DOMAIN OF THE HUMAN 1,25-DIHYDROXYVITAMIN D-3 RECEPTOR

      Molecular and cellular endocrinology
    33. NISHIMURA G; SATOH M; AIHARA T; AIDA N; YAMAMOTO T; OZONO K
      A DISTINCT SUBTYPE OF METATROPIC DYSPLASIA VARIANT CHARACTERIZED BY ADVANCED CARPAL SKELETAL AGE AND SUBLUXATION OF THE RADIAL HEADS

      Pediatric radiology
    34. SAKAI N; FUKUSHIMA H; INUI K; FU L; NISHIGAKI T; YANAGIHARA I; TATSUMI N; OZONO K; OKADA S
      HUMAN GALACTOCEREBROSIDASE GENE - PROMOTER ANALYSIS OF THE 5'-FLANKING REGION AND STRUCTURAL ORGANIZATION

      Biochimica et biophysica acta, N. Gene structure and expression
    35. CAI GM; NAKAYAMA M; HIRAKI Y; OZONO K
      MUTATIONAL ANALYSIS OF THE DTDST GENE IN A FETUS WITH ACHONDROGENESISTYPE 1B

      American journal of medical genetics
    36. CAI GM; MICHIGAMI T; YAMAMOTO T; YASUI N; SATOMURA K; YAMAGATA M; SHIMA M; NAKAJIMA S; MUSHIAKE S; OKADA S; OZONO K
      ANALYSIS OF LOCALIZATION OF MUTATED TISSUE NONSPECIFIC ALKALINE-PHOSPHATASE PROTEINS ASSOCIATED WITH NEONATAL HYPOPHOSPHATASIA USING GREEN FLUORESCENT PROTEIN CHIMERAS

      The Journal of clinical endocrinology and metabolism
    37. MUSHIAKE S; OZONO K; ETANI Y; TAJIRI H; OKADA S
      THE EXPRESSION OF THROMBOSPONDIN IN THE FIBROTIC LIVER OF BILIARY ATRESIA

      Gastroenterology
    38. ETANI Y; MUSHIAKE S; TAJIRI H; MIKI K; KOZAIWA K; SAWADA A; TADA K; OZONO K; OKADA S
      A NOVEL MUTATION OF THE DOWN-REGULATED IN ADENOMA (DRA) GENE IN A JAPANESE CASE WITH CONGENITAL CHLORIDE DIARRHEA

      Gastroenterology
    39. YAMAMOTO T; OZONO K; SHIMA M; YAMAOKA K; OKADA S
      24R,25-DIHYDROXYVITAMIN D-3 INCREASES CYCLIC-GMP CONTENTS, LEADING TOAN ENHANCEMENT OF OSTEOCALCIN SYNTHESIS BY 1,25-DIHYDROXYVITAMIN D-3 IN CULTURED HUMAN OSTEOBLASTIC CELLS

      Experimental cell research
    40. OZONO K; MUSHIAKE S; TAKESHIMA T; NAKAYAMA M
      DIAGNOSIS OF CONGENITAL CYTOMEGALOVIRUS-INFECTION BY EXAMINATION OF PLACENTA - APPLICATION OF POLYMERASE CHAIN-REACTION AND IN-SITU HYBRIDIZATION

      PEDIATRIC PATHOLOGY & LABORATORY MEDICINE
    41. OZONO K; ITO M; MIURA D; ISHIZUKA S; YANAGIHARA I; NAKAJIMA S
      NOVEL 1-ALPHA,25-DIHYDROXYVITAMIN D-3 ANALOG, TEI-9647, ACTS AS AN ANTAGONIST OF THE VITAMIN-D-RECEPTOR FUNCTION

      Journal of bone and mineral research
    42. ISHIZUKA S; MIURA D; MANABE K; GAO Q; SAKUMA Y; UNO H; OZONO K
      NOVEL 1-ALPHA,25-DIHYDROXVITAMIN D3-26,23-LACTONE ANALOGS FUNCTIONS AS ANTAGONISTS OF VITAMIN-D RECEPTOR-MEDIATED GENOMIC ACTIONS OF 1-ALPHA,25-DIHYDROXYVITAMIN D3

      Journal of bone and mineral research
    43. OZONO K
      RECENT ADVANCES IN MOLECULAR ANALYSIS OF SKELETAL DYSPLASIA

      Acta Paediatrica Japonica Overseas Edition
    44. KAMEYAMA A; YAZAWA K; KAIBARA M; OZONO K; KAMEYAMA M
      RUN-DOWN OF THE CARDIAC CA2- CHARACTERIZATION AND RESTORATION OF CHANNEL ACTIVITY BY CYTOPLASMIC FACTORS( CHANNEL )

      Pflugers Archiv
    45. NAKAJIMA S; YANAGIHARA I; OZONO K
      A 65-KILODALTON NUCLEAR-PROTEIN BINDS TO THE HUMAN VITAMIN-D-RECEPTOR- A BACTERIAL-EXPRESSED HISTIDINE-TAGGED RECEPTOR STUDY

      Biochemical and biophysical research communications
    46. NAKAJIMA S; YAMAGATA M; OZONO K
      EFFECTS OF CYCLIC ADENOSINE-MONOPHOSPHATE AND PROTEIN KINASE-A ON LIGAND-DEPENDENT TRANSACTIVATION VIA VITAMIN-D-RECEPTOR

      Journal of bone and mineral research
    47. YAMAMOTO T; OZONO K; KASAYAMA S; TAKAGI M; MATSUMOTO S; MICHIGAMI T; SHIMA M; YAMAOKA K; YOH K; KISHIMOTO T; OKADA S
      GS-ALPHA MUTATION IN MCCUNE-ALBRIGHT SYNDROME IS LINKED TO THE INCREASED IL-6 PRODUCTION BY THE FIBROUS CELLS ISOLATED FROM THE BONE-LESIONS

      Journal of bone and mineral research
    48. OZONO K; YAMAGATA M; SAKAI N; YABUTA K; TOKITA A; NAKAJIMA S
      MESSENGER-RNA LEVEL OF THE ALLELE WITH TAQI-DIGESTIVE SITE IS LOWER THAN THAT WITHOUT THE SITE IN VITAMIN-D-RECEPTOR GENE

      Journal of bone and mineral research
    49. MATSUMOTO S; YAMAMOTO T; OZONO K; YAMAOKA K; MICHIGAMI T; SATOMURA K; SHIMA M; MATSUMOTO K; NAKAMURA T; OKADA S
      IMPAIRED HEPATOCYTE GROWTH-FACTOR ACTIONS IN THE OSTEOBLAST ISOLATED FROM A CASE OF MALIGNANT OSTEOPETROSIS

      Journal of bone and mineral research
    50. YAMAMOTO T; OZONO K; MATSUMOTO S; YOH K; SHIMA M; SHIMIZU N; NAKAMURA K; HIRAI H; YAMAOKA K; OKADA S
      HUMORAL FACTOR IS INVOLVED IN THE PATHOGENESIS OF HYPOPHOSPHATEMIC RICKETS COMPLICATED WITH MCCUNE-ALBRIGHT SYNDROME

      Journal of bone and mineral research
    51. OZONO K; YAMAGATA M; MICHIGAMI T; CAI G; SAKAI N; SATOMURA K; NAKAJIMA S; NAKAYAMA M
      IDENTIFICATION OF NOVEL MUTATIONS IN A SURVIVING CASE OF PERINATAL HYPOPHOSPHATASIA

      Journal of bone and mineral research
    52. KAMIMURA S; YAMAMOTO J; KODAMA J; TOKUMO K; ITO H; OZONO K; TANAKA H; KOBASHI Y; HIRAMATSU Y; KUDO T
      HUMORAL HYPERCALCEMIA OF MALIGNANCY DUE TO INCREASED PTHRP WITHOUT INHIBITION OF 1-ALPHA-HYDROXYLASE ACTIVITY

      Journal of bone and mineral research
    53. YAMAMOTO T; OZONO K; KASAYAMA S; YOH K; HIROSHIMA K; TAKAGI M; MATSUMOTO S; MICHIGAMI T; YAMAOKA K; KISHIMOTO T; OKADA S
      INCREASED IL-6 PRODUCTION BY CELLS ISOLATED FROM THE FIBROUS BONE DYSPLASIA TISSUES IN PATIENTS WITH MCCUNE-ALBRIGHT SYNDROME

      The Journal of clinical investigation
    54. MICHIGAMI T; YAMATO H; MUSHIAKE S; NAKAYAMA M; YONEDA A; SATOMURA K; IMURA K; OZONO K
      HYPERCALCEMIA ASSOCIATED WITH INFANTILE FIBROSARCOMA PRODUCING PARATHYROID HORMONE-RELATED PROTEIN

      The Journal of clinical endocrinology and metabolism
    55. OZONO K; YAMAGATA M; MICHIGAMI T; NAKAJIMA S; SAKAI N; CAI GM; SATOMURA K; YASUI N; OKADA S; NAKAYAMA M
      IDENTIFICATION OF NOVEL MISSENSE MUTATIONS (PHE310LEU AND GLY439ARG) IN A NEONATAL CASE OF HYPOPHOSPHATASIA

      The Journal of clinical endocrinology and metabolism
    56. OHYAMA Y; OZONO K; UCHIDA M; YOSHIMURA M; SHINKI T; SUDA T; YAMAMOTO O
      FUNCTIONAL ASSESSMENT OF 2 VITAMIN-D-RESPONSIVE ELEMENTS IN THE RAT 25-HYDROXYVITAMIN-D-3 24-HYDROXYLASE GENE

      The Journal of biological chemistry
    57. SADAMATSU K; HARASAWA Y; OZONO K; YASUTSUNE T; MASUDA M; KAWACHI Y; YASUI H; TAKESHITA A
      A RARE CASE OF LARGE VENTRICULAR SEPTAL-DEFECT WITH MINIMAL PULMONARYVASCULAR OBSTRUCTIVE CHANGES IN A 41-YEAR-OLD WOMAN

      Heart and vessels
    58. OZONO K; OHYAMA Y; NAKAJIMA S; UCHIDA M; YOSHIMURA M; SHINKI T; SUDA T; YAMAMOTO O
      CHARACTERIZATION OF 2 VITAMIN-D-RESPONSIVE ELEMENTS IN THE RAT 25-HYDROXYVITAMIN-D3 24-HYDROXYLASE GENE

      Journal of bone and mineral research
    59. MICHIGAMI T; YAMATO H; NAKAJIMA S; MUSHIAKE S; NAKAYAMA M; SATOMURA K; OZONO K
      PARATHYROID-HORMONE RELATED PEPTIDE-PRODUCING INFANTILE FIBROSARCOMA TRANSPLANTABLE TO NUDE RATS

      Journal of bone and mineral research
    60. YAMAMOTO T; OZONO K; KASAYAMA S; YOH K; HIROSHIMA K; MATSUMOTO S; MICHIAMI T; TAKAGI M; YAMAOKA K; KISHIMOTO T; OKADA S
      THE ROLE OF GS-ALPHA-MUTATION IN THE PATHOGENESIS OF BONE-DISEASE IN MCCUNE-ALBRIGHT-SYNDROME - INCREASED IL-6 PRODUCTION BY THE MUTATED FIBROUS CELLS IS ASSOCIATED WITH THE HIGH TURNOVER BONE-DISEASE

      Journal of bone and mineral research
    61. MIKUNITAKAGAKI Y; SUZUKI Y; KUBOTA T; SAITO S; YAMAGUCHI A; MICHIGAMI T; OZONO K; SHIMA M; YAMAOKA K; OKADA S; YAMAMOTO T
      MECHANICAL-STRESS RESTORES IMPAIRED FUNCTION OF OSTEOCYTES IN X-LINKED, VITAMIN-D-RESISTANT HYPOPHOSPHATEMIC RICKETS

      Journal of bone and mineral research
    62. OKAMOTO N; WADA Y; IDA S; KOGA R; OZONO K; CHIYO H; HAYASHI A; TATSUMI K
      MONOALLELIC EXPRESSION OF NORMAL MESSENGER-RNA IN THE PIT1 MUTATION HETEROZYGOTES WITH NORMAL PHENOTYPE AND BIALLELIC EXPRESSION IN THE ABNORMAL PHENOTYPE

      Human molecular genetics
    63. UCHIDA M; OZONO K; PIKE JW
      ACTIVATION OF THE HUMAN OSTEOCALCIN GENE BY 24R,25-DIHYDROXYVITAMIN-D-3 OCCURS THROUGH THE VITAMIN-D-RECEPTOR AND THE VITAMIN-D RESPONSIVE ELEMENT

      Journal of bone and mineral research
    64. OHYAMA Y; OZONO K; UCHIDA M; SHINKI T; KATO S; SUDA T; YAMAMOTO O; NOSHIRO M; KATO Y
      IDENTIFICATION OF A VITAMIN-D-RESPONSIVE ELEMENT IN THE 5'-FLANKING REGION OF THE RAT 25-HYDROXYVITAMIN D-3 24-HYDROXYLASE GENE

      The Journal of biological chemistry
    65. OHYAMA Y; OZONO K; UCHIDA M; NOSHIRO M; KATO Y
      SEQUENCE ELEMENTS IN THE RAT 25-HYDROXYVITAMIN-D(3)-24-HYDROXYLASE WHICH CONFER RESPONSIVENESS TO VITAMIN-D

      Journal of bone and mineral research
    66. YAMAMOTO T; YAMAOKA K; OZONO K; YAMAMOTO K; MATSUMOTO S; MICHIGAMI T; SHIMA M; TAKAOKA K; HIROSHIMA K; OKADA S
      G-KINASE MEDIATES THE COOPERATIVE EFFECT OF 24,25(OH)2D(3) ON BGP PRODUCTION INDUCED BY 1,25(OH)2D(3) IN HUMAN BONE-CELLS

      Journal of bone and mineral research


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Documento generato il 21/10/20 alle ore 16:09:03