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Inverse agonist properties of antipsychotic agents at cloned, human (h) serotonin (5-HT)(1B) and h5-HT1D receptors
NEUROPSYCHOPHARMACOLOGY
Constitutive activity at serotonin 5-HT1D receptors: detection by homologous GTP gamma S versus [S-35]-GTP gamma S binding isotherms
NEUROPHARMACOLOGY
Pindolol antagonises G-protein activation at both pre- and postsynaptic serotonin 5-HT1A receptors: a [S-35]GTP gamma S autoradiography study
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
S33005, a novel ligand at both serotonin and norepinephrine transporters: I. Receptor binding, electrophysiological, and neurochemical profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Antiparkinsonian agent piribedil displays antagonist properties at native,rat, and cloned, human alpha(2)-adrenoceptors: Cellular and functional characterization
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Potential antidepressants displayed combined alpha(2)-adrenoceptor antagonist and monoamine uptake inhibitor properties
JOURNAL OF MEDICINAL CHEMISTRY
Efficacy of antipsychotic agents at human 5-HT1A receptors determined by [H-3]WAY100,635 binding affinity ratios: Relationship to efficacy for G-protein activation
EUROPEAN JOURNAL OF PHARMACOLOGY
Agonist properties of pindolol at h5-HT1A receptors coupled to mitogen-activated protein kinase
EUROPEAN JOURNAL OF PHARMACOLOGY
Differential modulation by GTP gamma S of agonist and inverse agonist binding to h5-HT1A receptors revealed by [H-3]-WAY100,635
BRITISH JOURNAL OF PHARMACOLOGY
The '' selective '' dopamine D-1 receptor antagonist, SCH23390, is a potent and high efficacy agonist at cloned human serotonin(2C) receptors
PSYCHOPHARMACOLOGY
Mirtazapine enhances frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission by blockade of alpha(2)-adrenergic and serotonin(2C) receptors: a comparison with citalopram
EUROPEAN JOURNAL OF NEUROSCIENCE
Serotonin(2C) receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: A combined dialysis and electrophysiological analysis in the rat
SYNAPSE
Agonist and antagonist actions of yohimbine as compared to fluparoxan at alpha(2)-adrenergic receptors (AR)s, serotonin (5-HT)(1A), 5-HT1B, 5-HT1D and dopamine D-2 and D-3 receptors. Significance for the modulation of frontocortical monoaminergic transmission and depressive states
SYNAPSE
Activation of dopamine D-3 receptors induces c-fos expression in primary cultures of rat striatal neurons
JOURNAL OF NEUROSCIENCE RESEARCH
[S-35]-GTP gamma S autoradiography reveals alpha(2) adenoceptor-mediated G-protein activation in amygdala and lateral septum
NEUROPHARMACOLOGY
Antagonist properties of the novel antipsychotic, S16924, at cloned, humanserotonin 5-HT2C receptors: a parallel phosphatidylinositol and calcium accumulation comparison with clozapine and haloperidol
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
[H-3]S33084: a novel, selective and potent radioligand at cloned, human dopamine D-3 receptors
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
An innovative method for rapid characterisation of phospholipase C activity: SB242,084 competitively antagonises 5-HT2C receptor-mediated [H-3]phosphatidylinositol depletion
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Inverse agonism and constitutive activity as functional correlates of serotonin h5-HT1B receptor/G-protein stoichiometry
MOLECULAR PHARMACOLOGY
S18616, a highly potent, spiroimidazoline agonist at alpha(2)-adrenoceptors: I. Receptor profile, antinociceptive and hypothermic actions in comparison with dexmedetomidine and clonidine
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
S33084, a novel, potent, selective, and competitive antagonist at dopamineD-3-receptors: I. Receptorial, electrophysiological and neurochemical profile compared with GR218,231 and L741,626
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
S18327 (1-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperid-1-yl]ethyl}3-phenyl imidazolin-2-one), a novel, potential antipsychotic displaying marked antagonist properties at alpha(1) and alpha(2)-adrenergic receptors: I. Receptorial, neurochemical, and electrophysiological profile
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
S18327 (1-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperid-1-yl]ethyl}3-phenyl imidazolin-2-one), a novel, potential antipsychotic displaying marked antagonist properties at alpha(1) and alpha(2)-adrenergic receptors: II. Functional profile and a multiparametric comparison with haloperidol, clozapine,and 11 other antipsychotic agents
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
The novel antagonist, S33084, and CR218,231 interact selectively with cloned and native, rat dopamine D-3 receptors as compared with native, rat dopamine D-2 receptors
EUROPEAN JOURNAL OF PHARMACOLOGY
Novel benzopyrano[3,4-c]pyrrole derivatives as potent and selective dopamine D-3 receptor antagonists
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Contrasting mechanisms of action and sensitivity to antipsychotics of phencyclidine versus amphetamine: importance of nucleus accumbens 5-HT2A sites for PCP-induced locomotion in the rat
EUROPEAN JOURNAL OF NEUROSCIENCE
Inverse agonists and serotonergic transmission: From recombinant, human serotonin (5-HT)(1B) receptors to G-protein coupling and function in corticolimbic structures in vivo
NEUROPSYCHOPHARMACOLOGY
Actions of roxindole at recombinant human dopamine D-2, D-3 and D-4 and serotonim 5-HT1A, 5-HT1B and 5-HT1D receptors
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Human dopamine D-3 receptors mediate mitogen- activated protein kinase activation via a phosphatidylinositol 3-kinase and an atypical protein kinase C-dependent mechanism
MOLECULAR PHARMACOLOGY
G protein activation by human dopamine D-3 receptors in high-expressing Chinese hamster ovary cells: A guanosine-5 '-O-(3-[S-35]thio)-triphosphate binding and antibody study
MOLECULAR PHARMACOLOGY
The 5HT(1A) receptor ligand, S15535, antagonises G-protein activation: a [S-35]GTP gamma S and [H-3]S15535 autoradiography study
EUROPEAN JOURNAL OF PHARMACOLOGY