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    1. Clark, KJ; Cary, NR; Grace, AA; Metcalfe, JC
      Microsatellite mutation of type II transforming growth factor-beta receptor is rare in atherosclerotic plaques

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    2. Griggs, J; Brindle, KM; Metcalfe, JC; Hill, SA; Smith, GA; Beauregard, DA; Hesketh, R
      Potent anti-metastatic activity of combretastatin-A4

      INTERNATIONAL JOURNAL OF ONCOLOGY
    3. Reckless, J; Rubin, EM; Verstuyft, JB; Metcalfe, JC; Grainger, DJ
      A common phenotype associated with atherogenesis in diverse mouse models of vascular lipid lesions

      JOURNAL OF VASCULAR RESEARCH
    4. Martin, KM; Metcalfe, JC; Kemp, PR
      Expression of Klf9 and Klf13 in mouse development

      MECHANISMS OF DEVELOPMENT
    5. Clarke, SC; Schofield, PM; Grace, AA; Metcalfe, JC; Kirschenlohr, HL
      Tamoxifen effects on endothelial function and cardiovascular risk factors in men with advanced atherosclerosis

      CIRCULATION
    6. Lucke, CD; Philpott, A; Metcalfe, JC; Thompson, AM; Hughes-Davies, L; Kemp, PR; Hesketh, R
      Inhibiting mutations in the transforming growth factor beta type 2 receptor in recurrent human breast cancer

      CANCER RESEARCH
    7. Griggs, J; Hesketh, R; Smith, GA; Brindle, KM; Metcalfe, JC; Thomas, GA; Williams, ED
      Combretastatin-A4 disrupts neovascular development in non-neoplastic tissue

      BRITISH JOURNAL OF CANCER
    8. Ellis, PD; Chen, Q; Barker, PJ; Metcalfe, JC; Kemp, PR
      Nov gene encodes adhesion factor for vascular smooth muscle cells and is dynamically regulated in response to vascular injury

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    9. Kirschenlohr, HL; Grace, AA; Vandenberg, JI; Metcalfe, JC; Smith, GA
      Estimation of systolic and diastolic free intracellular Ca2+ by titration of Ca2+ buffering in the ferret heart

      BIOCHEMICAL JOURNAL
    10. Smith, GA; Dixon, HBF; Kirschenlohr, HL; Grace, AA; Metcalfe, JC; Vandenberg, JI
      Ca2+ buffering in the heart: Ca2+ binding to and activation of cardiac myofibrils

      BIOCHEMICAL JOURNAL
    11. Kemp, PR; Metcalfe, JC
      Four isoforms of serum response factor that increase or inhibit smooth-muscle-specific promoter activity

      BIOCHEMICAL JOURNAL
    12. Martin, KM; Cooper, WN; Metcalfe, JC; Kemp, PR
      Mouse BTEB3, a new member of the basic transcription element binding protein (BTEB) family, activates expression from GC-rich minimal promoter regions

      BIOCHEMICAL JOURNAL
    13. Grainger, DJ; Mosedale, DE; Metcalfe, JC; Bottinger, EP
      Dietary fat and reduced levels of TGF beta 1 act synergistically to promote activation of the vascular endothelium and formation of lipid lesions

      JOURNAL OF CELL SCIENCE
    14. Grainger, DJ; Heathcote, K; Chiano, M; Snieder, H; Kemp, PR; Metcalfe, JC; Carter, ND; Spector, TD
      Genetic control of the circulating concentration of transforming growth factor type beta 1

      HUMAN MOLECULAR GENETICS
    15. Reckless, J; Rubin, EM; Verstuyft, JB; Metcalfe, JC; Grainger, DJ
      Monocyte chemoattractant protein-1 but not tumor necrosis factor-alpha is correlated with monocyte infiltration in mouse lipid lesions

      CIRCULATION
    16. LACYHULBERT A; METCALFE JC; HESKETH R
      BIOLOGICAL RESPONSES TO ELECTROMAGNETIC-FIELDS

      The FASEB journal
    17. Syrris, P; Carter, ND; Metcalfe, JC; Kemp, PR; Grainger, DJ; Kaski, JC; Crossman, DC; Francis, SE; Gunn, J; Jeffrey, S; Heathcote, K
      Transforming growth factor-beta gene polymorphisms and coronary artery disease

      CLINICAL SCIENCE
    18. GRAINGER DJ; METCALFE JC; GRACE AA; MOSEDALE DE
      TRANSFORMING-GROWTH-FACTOR-BETA DYNAMICALLY REGULATES VASCULAR SMOOTH-MUSCLE DIFFERENTIATION IN-VIVO

      Journal of Cell Science
    19. BYRNE CD; WAREHAM NJ; MARTENSZ ND; HUMPHRIES SE; METCALFE JC; GRAINGER DJ
      INCREASED PAI ACTIVITY AND PAI-1 ANTIGEN OCCURRING WITH AN ORAL FAT LOAD - ASSOCIATIONS WITH PAI-1 GENOTYPE AND PLASMA ACTIVE TGF-BETA LEVELS

      Atherosclerosis (Amsterdam)
    20. OKLU R; HESKETH TR; METCALFE JC; KEMP PR
      EXPRESSION OF ALTERNATIVELY SPLICED HUMAN LATENT TRANSFORMING-GROWTH-FACTOR-BETA BINDING PROTEIN-1

      FEBS letters
    21. OKLU R; METCALFE JC; HESKETH TR; KEMP PR
      LOSS OF A CONSENSUS HEPARIN-BINDING SITE BY ALTERNATIVE SPLICING OF LATENT TRANSFORMING-GROWTH-FACTOR-BETA BINDING PROTEIN-1

      FEBS letters
    22. CLARKE SC; KELLEHER J; RIGLEY JM; SLACK M; METCALFE JC; SCHOFIELD PM
      THE EFFECT OF HORMONE REPLACEMENT THERAPY ON LIPID PROFILES IN POSTMENOPAUSAL WOMEN WITH ANGIOGRAPHICALLY PROVEN CORONARY-ARTERY DISEASE

      The American journal of cardiology
    23. CLARKE SC; BEDFORD ST; METCALFE JC; SCHOFIELD PM
      HORMONE REPLACEMENT THERAPY ENHANCES ENDOTHELIUM-DEPENDENT FLOW-MEDIATED VASODILATATION IN POSTMENOPAUSAL WOMEN WITH ANGIOGRAPHICALLY PROVEN CORONARY-ARTERY DISEASE

      The American journal of cardiology
    24. SMITH GA; KIRSCHENLOHR HL; GRACE AA; METCALFE JC; VANDENBERG JI
      BUFFERING OF THE CARDIAC CALCIUM TRANSIENT BY EXOGENOUS CALCIUM INDICATORS

      Journal of physiology
    25. GRAINGER DJ; BYRNE CD; WITCHELL CM; METCALFE JC
      TRANSFORMING-GROWTH-FACTOR-BETA IS SEQUESTERED INTO AN INACTIVE POOL BY LIPOPROTEINS

      Journal of lipid research
    26. BYRNE CD; WAREHAM NJ; HOWARD AN; WILLIAMS NR; METCALFE JC; GRAINGER DJ
      SMOKING IS STRONGLY ASSOCIATED WITH LOW-LEVELS OF ACTIVE TRANSFORMING-GROWTH-FACTOR-BETA (TGF-BETA) - A NOVEL LINK WITH ISCHEMIC-HEART-DISEASE

      Atherosclerosis
    27. BYRNE CD; WAREHAM NJ; CLARK PMS; MARTENSZ ND; HUMPHRIES SE; METCALFE JC; GRAINGER DJ
      PAI ACTIVITY AND PAI-1 ANTIGEN BOTH INCREASE DURING A FAT TOLERANCE-TEST - ASSOCIATIONS WITH PAI-1 GENOTYPE AND TGF-BETA LEVELS

      Atherosclerosis
    28. GRAINGER DJ; RECKLESS J; METCALFE JC; RUBIN EM; LAWN R
      LP(A) AND ENDOTHELIUM - A FEEDBACK LOOP IN ATHEROSCLEROSIS

      Atherosclerosis
    29. RECKLESS J; METCALFE JC; GRAINGER DJ
      TAMOXIFEN DECREASES CHOLESTEROL SEVENFOLD AND ABOLISHES LIPID LESION DEVELOPMENT IN APOLIPOPROTEIN-E KNOCKOUT MICE

      Circulation
    30. GRAINGER DJ; METCALFE JC
      TAMOXIFEN - TEACHING AN OLD DRUG NEW TRICKS

      Nature medicine
    31. VANDENBERG JI; CARTER ND; BETHELL HWL; NOGRADI A; RIDDERSTRALE Y; METCALFE JC; GRACE AA
      CARBONIC-ANHYDRASE AND CARDIAC PH REGULATION

      American journal of physiology. Cell physiology
    32. GRACE AA; METCALFE JC; WEISSBERG PL; BETHELL HWL; VANDENBERG JI
      ANGIOTENSIN-II STIMULATES SODIUM-DEPENDENT PROTON EXTRUSION IN PERFUSED FERRET HEART

      American journal of physiology. Cell physiology
    33. MOSEDALE DE; METCALFE JC; GRAINGER DJ
      OPTIMIZATION OF IMMUNOFLUORESCENCE METHODS BY QUANTITATIVE IMAGE-ANALYSIS

      The Journal of histochemistry and cytochemistry
    34. LAWN RM; PEARLE AD; KUNZ LL; RUBIN EM; RECKLESS J; METCALFE JC; GRAINGER DJ
      FEEDBACK MECHANISM OF FOCAL VASCULAR LESION FORMATION IN TRANSGENIC APOLIPOPROTEIN(A) MICE

      The Journal of biological chemistry
    35. LAWN RM; PEARLE AD; RECKLESS J; RUBIN EM; METCALFE JC; GRAINGER DJ
      FEEDBACK MECHANISM OF FOCAL VASCULAR LESION FORMATION IN TRANSGENIC APOLIPOPROTEIN(A) MICE

      Circulation
    36. GRAINGER DJ; WAKEFIELD L; BETHELL HW; FARNDALE RW; METCALFE JC
      RELEASE AND ACTIVATION OF PLATELET LATENT TGF-BETA IN BLOOD-CLOTS DURING DISSOLUTION WITH PLASMIN

      Nature medicine
    37. GRAINGER DJ; WITCHELL CM; METCALFE JC
      TAMOXIFEN ELEVATES TRANSFORMING GROWTH-FACTOR-BETA AND SUPPRESSES DIET-INDUCED FORMATION OF LIPID LESIONS IN MOUSE AORTA

      Nature medicine
    38. GRAINGER DJ; KEMP BR; METCALFE JC; LIU AC; LAWN RM; WILLIAMS NR; GRACE AA; SCHOFIELD PM; CHAUHAN A
      THE SERUM CONCENTRATION OF ACTIVE TRANSFORMING GROWTH-FACTOR-BETA IS SEVERELY DEPRESSED IN ADVANCED ATHEROSCLEROSIS

      Nature medicine
    39. METCALFE JC; GRAINGER DJ
      TGF-BETA - IMPLICATIONS FOR HUMAN VASCULAR-DISEASE

      Journal of human hypertension
    40. METCALFE JC; GRAINGER DJ
      TRANSFORMING GROWTH-FACTOR-BETA AND THE PROTECTION FROM CARDIOVASCULAR INJURY HYPOTHESIS

      Biochemical Society transactions
    41. KEMP PR; OSBOURN JK; GRAINGER DJ; METCALFE JC
      CLONING AND ANALYSIS OF THE PROMOTER REGION OF THE RAT SM22-ALPHA GENE

      Biochemical journal
    42. LACYHULBERT A; WILKINS RC; HESKETH TR; METCALFE JC
      NO EFFECT OF 60 HZ ELECTROMAGNETIC-FIELDS ON MYC OR BETA-ACTIN EXPRESSION IN HUMAN LEUKEMIC-CELLS

      Radiation research
    43. LACYHULBERT A; WILKINS RC; HESKETH TR; METCALFE JC
      CANCER RISK AND ELECTROMAGNETIC-FIELDS

      Nature
    44. KEMP PR; METCALFE JC; GRAINGER DJ
      ID - A DOMINANT-NEGATIVE REGULATOR OF SKELETAL-MUSCLE DIFFERENTIATION- IS NOT INVOLVED IN MATURATION OR DIFFERENTIATION OF VASCULAR SMOOTH-MUSCLE CELLS

      FEBS letters
    45. GRAINGER DJ; MOSEDALE DE; METCALFE JC; WEISSBERG PL; KEMP PR
      ACTIVE AND ACID-ACTIVATABLE TGF-BETA IN HUMAN SERA, PLATELETS AND PLASMA

      Clinica chimica acta
    46. KIRSCHENLOHR HL; METCALFE JC; WEISSBERG PL; GRAINGER DJ
      PROLIFERATION OF HUMAN AORTIC VASCULAR SMOOTH-MUSCLE CELLS IN CULTUREIS MODULATED BY ACTIVE TGF-BETA

      Cardiovascular Research
    47. GRAINGER DJ; METCALFE JC
      PIVOTAL ROLE FOR TGF-BETA IN ATHEROGENESIS

      Biological Reviews of the Cambridge Philosophical Society
    48. GRAINGER DJ; KEMP PR; WITCHELL CM; WEISSBERG PL; METCALFE JC
      TRANSFORMING GROWTH-FACTOR-BETA DECREASES THE RATE OF PROLIFERATION OF RAT VASCULAR SMOOTH-MUSCLE CELLS BY EXTENDING THE G(2) PHASE OF THE CELL-CYCLE AND DELAYS THE RISE IN CYCLIC-AMP BEFORE ENTRY INTO M-PHASE

      Biochemical journal
    49. GRAINGER DJ; KEMP PR; LIU AC; LAWN RM; METCALFE JC
      ACTIVATION OF TRANSFORMING GROWTH-FACTOR-BETA IS INHIBITED IN TRANSGENIC APOLIPOPROTEIN(A) MICE

      Nature
    50. SHANAHAN CM; CARY NRB; METCALFE JC; WEISSBERG PL
      HIGH EXPRESSION OF GENES FOR CALCIFICATION-REGULATING PROTEINS IN HUMAN ATHEROSCLEROTIC PLAQUES

      The Journal of clinical investigation
    51. MOSEDALE DE; METCALFE JC; GRAINGER DJ
      TRANSFORMING GROWTH-FACTOR-BETA IS CORRELATED WITH SMOOTH-MUSCLE CELL-DIFFERENTIATION IN-VIVO

      Circulation
    52. MOSEDALE DE; METCALFE JC; GRAINGER DJ
      TRANSFORMING GROWTH-FACTOR-BETA IS CORRELATED WITH SMOOTH-MUSCLE CELL-DIFFERENTIATION IN-VIVO

      Circulation
    53. GRAINGER DJ; KEMP PR; METCALFE JC; LIU AC; LAWN RM; GRACE AA; WILLIAMS NR; SCHOFIELD PM; CHAUHAN A
      ACTIVE TRANSFORMING GROWTH-FACTOR-BETA IS DEPRESSED IN PATIENTS WITH 3 VESSEL CORONARY-ARTERY DISEASE

      Circulation
    54. GRAINGER DJ; KEMP PR; METCALFE JC; LIU AC; LAWN RM; GRACE AA; WILLIAMS NR; SCHOFIELD PM; CHAUHAN A
      ACTIVE TRANSFORMING GROWTH-FACTOR-BETA IS DEPRESSED IN PATIENTS WITH 3 VESSEL CORONARY-ARTERY DISEASE

      Circulation
    55. GRAINGER DJ; KEMP PR; LIU AC; LAWN RM; METCALFE JC
      ACTIVATION OF TRANSFORMING GROWTH-FACTOR-BETA IS INHIBITED BY APOLIPOPROTEIN(A) IN-VIVO

      Circulation
    56. GRAINGER DJ; KEMP PR; LIU AC; LAWN RM; METCALFE JC
      ACTIVATION OF TRANSFORMING GROWTH-FACTOR-BETA IS INHIBITED BY APOLIPOPROTEIN(A) IN-VIVO

      Circulation
    57. CHAUHAN A; WILLIAMS NR; METCALFE JC; GRACE AA; LIU AC; LAWN RM; KEMP PR; SCHOFIELD PM; GRAINGER DJ
      ACTIVATION OF TRANSFORMING GROWTH-FACTOR-BETA IS INVERSELY CORRELATEDWITH 3 MAJOR RISK-FACTORS FOR CORONARY-ARTERY DISEASE - LIPOPROTEIN(A), LDL-CHOLESTEROL AND PLASMINOGEN-ACTIVATOR INHIBITOR-1

      Circulation
    58. CHAUHAN A; WILLIAMS NR; METCALFE JC; GRACE AA; LIU AC; LAWN RM; KEMP PR; SCHOFIELD PM; GRAINGER DJ
      ACTIVATION OF TRANSFORMING GROWTH-FACTOR-BETA IS INVERSELY CORRELATEDWITH 3 MAJOR RISK-FACTORS FOR CORONARY-ARTERY DISEASE - LIPOPROTEIN(A), LDL-CHOLESTEROL AND PLASMINOGEN-ACTIVATOR INHIBITOR-1

      Circulation
    59. GRAINGER DJ; WITCHELL CM; WEISSBERG PL; METCALFE JC
      MITOGENS FOR ADULT-RAT AORTIC VASCULAR SMOOTH-MUSCLE CELLS IN SERUM-FREE PRIMARY CULTURE

      Cardiovascular Research
    60. VANDENBERG JI; METCALFE JC; GRACE AA
      INTRACELLULAR PH RECOVERY DURING RESPIRATORY-ACIDOSIS IN PERFUSED HEARTS

      The American journal of physiology
    61. RODEN RBS; SHACHARHILL Y; COSULICH SC; HESKETH TR; METCALFE JC
      A COMMON REQUIREMENT FOR P21(C-RAS) FUNCTION IN THE MITOGENIC SIGNALING PATHWAYS OF SWISS 3T3 FIBROBLASTS

      Cell growth & differentiation
    62. HARDING DP; SMITH GA; METCALFE JC; MORRIS PG; KIRSCHENLOHR HL
      RESTING AND END-DIASTOLIC [CA2-PERFUSED FERRET HEART LOADED WITH A F-19 NMR INDICATOR(]I MEASUREMENTS IN THE LANGENDORFF)

      Magnetic resonance in medicine
    63. CLARKE SD; METCALFE JC; SMITH GA
      DESIGN AND PROPERTIES OF NEW F-19 NMR CA2- MODULATION OF THE AFFINITIES OF BAPTA DERIVATIVES VIA ALKYLATION( INDICATORS )

      Perkin transactions. 2
    64. SMITH GA; METCALFE JC; CLARKE SD
      THE DESIGN AND PROPERTIES OF A SERIES OF CALCIUM INDICATORS WHICH SHIFT FROM RHODAMINE-LIKE TO FLUORESCEIN-LIKE FLUORESCENCE ON BINDING CALCIUM

      Perkin transactions. 2
    65. SMITH GA; KIRSCHENLOHR HL; METCALFE JC; CLARKE SD
      A NEW F-19 NMR INDICATOR FOR INTRACELLULAR SODIUM

      Perkin transactions. 2
    66. GRAINGER DJ; WEISSBERG PL; METCALFE JC
      TAMOXIFEN DECREASES THE RATE OF PROLIFERATION OF RAT VASCULAR SMOOTH-MUSCLE CELLS IN CULTURE BY INDUCING PRODUCTION OF TRANSFORMING GROWTH-FACTOR-BETA

      Biochemical journal
    67. KIRSCHENLOHR HL; GRACE AA; CLARKE SD; SHACHARHILL Y; METCALFE JC; MORRIS PG; SMITH GA
      CALCIUM MEASUREMENTS WITH A NEW HIGH-AFFINITY NMR INDICATOR IN THE ISOLATED-PERFUSED HEART

      Biochemical journal
    68. COSULICH SC; OFFER J; SMITH GA; HESKETH R; METCALFE JC
      EFFECTS OF FLUORINATED INOSITOLS ON THE PROLIFERATION OF SWISS 3T3 FIBROBLASTS

      Biochemical journal
    69. OFFER J; METCALFE JC; SMITH GA
      THE UPTAKE OF H-3 LABELED MONODEOXYFLUORO-MYO-INOSITOLS INTO THYMOCYTES AND THEIR INCORPORATION INTO PHOSPHOLIPID IN PERMEABILIZED CELLS (VOL 291, PG 553, 1993)

      Biochemical journal
    70. OFFER J; METCALFE JC; SMITH GA
      THE UPTAKE OF H-3 LABELED MONODEOXYFLUORO-MYO-INOSITOLS INTO THYMOCYTES AND THEIR INCORPORATION INTO PHOSPHOLIPID IN PERMEABILIZED CELLS

      Biochemical journal
    71. GRAINGER DJ; KIRSCHENLOHR HL; METCALFE JC; WEISSBERG PL; WADE DP; LAWN RM
      PROLIFERATION OF HUMAN SMOOTH-MUSCLE CELLS PROMOTED BY LIPOPROTEIN(A)

      Science
    72. KEMP PR; SHACHARHILL Y; WEISSBERG PL; METCALFE JC
      INHIBITION OF PDGF BB STIMULATED DNA-SYNTHESIS IN RAT AORTIC VASCULARSMOOTH-MUSCLE CELLS BY THE EXPRESSION OF A TRUNCATED PDGF-BETA RECEPTOR

      FEBS letters
    73. SHANAHAN CM; WEISSBERG PL; METCALFE JC
      ISOLATION OF GENE MARKERS OF DIFFERENTIATED AND PROLIFERATING VASCULAR SMOOTH-MUSCLE CELLS

      Circulation research
    74. VANDENBERG JI; METCALFE JC; GRACE AA
      MECHANISMS OF PH(I) RECOVERY AFTER GLOBAL-ISCHEMIA IN THE PERFUSED HEART

      Circulation research
    75. GRACE AA; METCALFE JC; BETHELL HW; VANDENBERG JI
      ANGIOTENSIN-II STIMULATES PROTON EXTRUSION DURING REPERFUSION

      Circulation
    76. WEISSBERG PL; GRAINGER DJ; SHANAHAN CM; METCALFE JC
      APPROACHES TO THE DEVELOPMENT OF SELECTIVE INHIBITORS OF VASCULAR SMOOTH-MUSCLE CELL-PROLIFERATION

      Cardiovascular Research
    77. GRAINGER DJ; WITCHELL CM; WATSON JV; METCALFE JC; WEISSBERG PL
      HEPARIN DECREASES THE RATE OF PROLIFERATION OF RAT VASCULAR SMOOTH-MUSCLE CELLS BY RELEASING TRANSFORMING GROWTH-FACTOR BETA-LIKE ACTIVITY FROM SERUM

      Cardiovascular Research
    78. KIRSCHENLOHR HL; METCALFE JC; WEISSBERG PL; GRAINGER DJ
      ADULT HUMAN AORTIC SMOOTH-MUSCLE CELLS IN CULTURE PRODUCE ACTIVE TGF-BETA

      The American journal of physiology
    79. GRACE AA; KIRSCHENLOHR HL; METCALFE JC; SMITH GA; WEISSBERG PL; CRAGOE EJ; VANDENBERG JI
      REGULATION OF INTRACELLULAR PH IN THE PERFUSED HEART BY EXTERNAL HCO3- AND NA-H+ EXCHANGE()

      The American journal of physiology


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Documento generato il 06/06/20 alle ore 13:17:13