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    1. Metzger, JM; Oren, R
      The effect of crown dimensions on transparency and the assessment of tree health

      ECOLOGICAL APPLICATIONS
    2. Westfall, MV; Turner, II; Albayya, FP; Metzger, JM
      Troponin I chimera analysis of the cardiac myofilament tension response toprotein kinase A

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    3. Szatkowski, ML; Westfall, MV; Gomez, CA; Wahr, PA; Michele, DE; DelloRusso, C; Turner, II; Hong, KE; Albayya, FP; Metzger, JM
      In vivo acceleration of heart relaxation performance by parvalbumin gene delivery

      JOURNAL OF CLINICAL INVESTIGATION
    4. Lu, Z; Swartz, DR; Metzger, JM; Moss, RL; Walker, JW
      Regulation of force development studied by photolysis of caged ADP in rabbit skinned psoas fibers

      BIOPHYSICAL JOURNAL
    5. Chen, AS; Marsh, DJ; Trumbauer, ME; Frazier, EG; Guan, XM; Yu, H; Rosenblum, CI; Vongs, A; Feng, Y; Cao, LH; Metzger, JM; Strack, AM; Camacho, RE; Mellin, TN; Nunes, CN; Min, W; Fisher, J; Gopal-Truter, S; MacIntyre, DE; Chen, HY; Van der Ploeg, LHT
      Inactivation of the mouse melanocortin-3 receptor results in increased fatmass and reduced lean body mass

      NATURE GENETICS
    6. Michele, DE; Metzger, JM
      Contractile dysfunction in hypertrophic cardiomyopathy: Elucidating primary defects of mutant contractile proteins by gene transfer

      TRENDS IN CARDIOVASCULAR MEDICINE
    7. Chen, AS; Metzger, JM; Trumbauer, ME; Guan, XM; Yu, H; Frazier, EG; Marsh, DJ; Forrest, MJ; Gopal-Truter, S; Fisher, J; Camacho, RE; Strack, AM; Mellin, TN; MacIntyre, DE; Chen, HY; Van der Ploeg, LHT
      Role of the melanocortin-4 receptor in metabolic rate and food intake in mice

      TRANSGENIC RESEARCH
    8. Michele, DE; Metzger, JM
      Physiological consequences of tropomyosin mutations associated with cardiac and skeletal myopathies

      JOURNAL OF MOLECULAR MEDICINE-JMM
    9. Wahr, PA; Michele, DE; Metzger, JM
      Effects of aging on single cardiac myocyte function in Fischer 344 x BrownNorway rats

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    10. Metzger, JM; Flemings, PB; Christie-Blick, N; Mountain, GS; Austin, JA; Hesselbo, SP
      Late Miocene to Pleistocene sequences at the New Jersey outer continental shelf (ODP leg 174A, sites 1071 and 1072)

      SEDIMENTARY GEOLOGY
    11. Hale, JJ; Mills, SG; MacCoss, M; Dorn, CP; Finke, PE; Budhu, RJ; Reamer, RA; Huskey, SEW; Luffer-Atlas, D; Dean, BJ; McGowan, EM; Feeney, WP; Chiu, SHL; Cascieri, MA; Chicchi, GG; Kurtz, MM; Sadowski, S; Ber, E; Tattersall, FD; Rupniak, NMJ; Williams, AR; Rycroft, W; Hargreaves, R; Metzger, JM; MacIntyre, DE
      Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs

      JOURNAL OF MEDICINAL CHEMISTRY
    12. Westfall, MV; Albayya, FP; Turner, II; Metzger, JM
      Chimera analysis of troponin I domains that influence Ca2+-activated myofilament tension in adult cardiac myocytes

      CIRCULATION RESEARCH
    13. Michele, DE; Albayya, FP; Metzger, JM
      Direct, convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant alpha-tropomyosins in adult cardiac myocytes

      NATURE MEDICINE
    14. Wahr, PA; Michele, DE; Metzger, JM
      Parvalbumin gene transfer corrects diastolic dysfunction in diseased cardiac myocytes

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    15. Michele, DE; Albayya, FP; Metzger, JM
      A nemaline myopathy mutation in alpha-tropomyosin causes defective regulation of striated muscle force production

      JOURNAL OF CLINICAL INVESTIGATION
    16. Rust, EM; Albayya, FP; Metzger, JM
      Identification of a contractile deficit in adult cardiac myocytes expressing hypertrophic cardiomyopathy-associated mutant troponin T proteins

      JOURNAL OF CLINICAL INVESTIGATION
    17. Michele, DE; Albayya, FP; Metzger, JM
      Thin filament protein dynamics in fully differentiated adult cardiac myocytes: Toward a model of sarcomere maintenance

      JOURNAL OF CELL BIOLOGY
    18. Westfall, MV; Albayya, FP; Metzger, JM
      Functional analysis of troponin I regulatory domains in the intact myofilament of adult single cardiac myocytes

      JOURNAL OF BIOLOGICAL CHEMISTRY
    19. Metzger, JM; Wahr, PA; Michele, DE; Albayya, F; Westfall, MV
      Effects of myosin heavy chain isoform switching on Ca2+-activated tension development in single adult cardiac myocytes

      CIRCULATION RESEARCH
    20. Wahr, PA; Metzger, JM
      Role of Ca2+ and cross-bridges in skeletal muscle thin filament activationprobed with Ca2+ sensitizers

      BIOPHYSICAL JOURNAL
    21. WAHR PA; METZGER JM
      PEAK POWER OUTPUT IS MAINTAINED IN RABBIT PSOAS AND RAT SOLEUS SINGLEMUSCLE-FIBERS WHEN CTP REPLACES ATP

      Journal of applied physiology (1985)
    22. RUST EM; WESTFALL MV; METZGER JM
      STABILITY OF THE CONTRACTILE ASSEMBLY AND CA2-ACTIVATED TENSION IN ADENOVIRUS-INFECTED ADULT CARDIAC MYOCYTES()

      Molecular and cellular biochemistry
    23. STEVENSON GI; HUSCROFT I; MACLEOD AM; SWAIN CJ; CASCIERI MA; CHICCHI GG; GRAHAM MI; HARRISON T; KELLEHER FJ; KURTZ M; LADDUWAHETTY T; MERCHANT KJ; METZGER JM; MACINTYRE DE; SADOWSKI S; SOHAL B; OWENS AP
      4,4-DISUBSTITUTED PIPERIDINE HIGH-AFFINITY NK1 ANTAGONISTS - STRUCTURE-ACTIVITY-RELATIONSHIPS AND IN-VIVO ACTIVITY

      Journal of medicinal chemistry
    24. FISHER MH; AMEND AM; BACH TJ; BARKER JM; BRADY EJ; CANDELORE MR; CARROLL D; CASCIERI MA; CHIU SHL; DENG LP; FORREST MJ; HEGARTYFRISCINO B; GUAN XM; HOM GJ; HUTCHINS JE; KELLY LJ; MATHVINK RJ; METZGER JM; MILLER RR; OK HO; PARMEE ER; SAPERSTEIN R; STRADER CD; STEARNS RA; THOMPSON GM; TOTA L; VICARIO PP; WEBER AE; WOODS JW; WYVRATT MJ; ZAFIAN PT; MACINTYRE DE
      A SELECTIVE HUMAN BETA(3) ADRENERGIC-RECEPTOR AGONIST INCREASES METABOLIC-RATE IN RHESUS-MONKEYS

      The Journal of clinical investigation
    25. CHALLET E; NAYLOR E; METZGER JM; MACINTYRE DE; TUREK FW
      AN NK1 RECEPTOR ANTAGONIST AFFECTS THE CIRCADIAN REGULATION OF LOCOMOTOR-ACTIVITY IN GOLDEN-HAMSTERS

      Brain research
    26. WESTFALL MV; ALBAYYA F; METZGER JM
      GENETIC DISSECTION OF THE PUTATIVE MOLECULAR SWITCH DOMAIN OF TROPONIN-I IN CARDIAC MYOCYTES

      Biophysical journal
    27. MICHELE DE; METZGER JM
      VISUALIZATION OF TROPOMYOSIN TURNOVER AND INCORPORATION IN ADULT CARDIAC MYOCYTES

      Biophysical journal
    28. RUST EM; ALBAYYA FP; METZGER JM
      THE EFFECTS OF MUTANT TROPONIN-T GENE-TRANSFER ON ADULT CARDIAC MYOCYTE STRUCTURE AND FUNCTION

      Biophysical journal
    29. WAHR PA; METZGER JM
      CAFFEINE REDUCES MAXIMUM CROSSBRIDGE CYCLING IN SKINNED RAT SOLEUS FIBERS

      Biophysical journal
    30. WAHR PA; METZGER JM
      EFFECT OF CA ACTIVATION LEVEL ON RATES OF FORCE DEVELOPMENT AND RELAXATION FOLLOWING PHOTOLYSIS OF NP-EGTA AND DIAZO-2

      Biophysical journal
    31. RUST EM; WESTFALL MV; SAMUELSON LC; METZGER JM
      GENE-TRANSFER INTO MOUSE EMBRYONIC STEM CELL-DERIVED CARDIAC MYOCYTESMEDIATED BY RECOMBINANT ADENOVIRUS

      In vitro cellular & developmental biology. Animal
    32. METZGER JM; SAMUELSON LC; RUST EM; WESTFALL MV
      EMBRYONIC STEM-CELL CARDIOGENESIS - APPLICATIONS FOR CARDIOVASCULAR RESEARCH

      Trends in cardiovascular medicine
    33. WESTFALL MV; PASYK KA; YULE DI; SAMUELSON LC; METZGER JM
      ULTRASTRUCTURE AND CELL-CELL COUPLING OF CARDIAC MYOCYTES DIFFERENTIATING IN EMBRYONIC STEM-CELL CULTURES

      Cell motility and the cytoskeleton
    34. WESTFALL MV; RUST EM; METZGER JM
      SLOW SKELETAL TROPONIN-I GENE-TRANSFER, EXPRESSION, AND MYOFILAMENT INCORPORATION ENHANCES ADULT CARDIAC MYOCYTE CONTRACTILE FUNCTION

      Proceedings of the National Academy of Sciences of the United Statesof America
    35. ACAKPOSATCHIVI LJR; EDELMANN W; SARTORIUS C; LU BD; WAHR PA; WATKINS SC; METZGER JM; LEINWAND L; KUCHERLAPATI R
      GROWTH AND MUSCLE DEFECTS IN MICE LACKING ADULT MYOSIN HEAVY-CHAIN GENES

      The Journal of cell biology
    36. WESTFALL MV; RUST EM; METZGER JM
      SLOW SKELETAL TROPONIN-I GENE-TRANSFER INTO ADULT CARDIAC MYOCYTES - THIN FILAMENT INCORPORATION AND ENHANCED CONTRACTILITY

      Biophysical journal
    37. WAHR PA; METZGER JM
      EFFECTS OF CTP ON POWER OUTPUT OF FAST AND SLOW SINGLE SKINNED SKELETAL-MUSCLE FIBERS

      Biophysical journal
    38. METZGER JM
      EFFECTS OF SKELETAL ALPHA-ACTIN ISOFORM EXPRESSION ON CONTRACTILE FUNCTION OF CARDIAC MYOCYTES ISOLATED FROM BALB C MICE/

      Biophysical journal
    39. RUST EM; MICHELE DE; WESTFALL MV; METZGER JM
      ADENOVIRUS-MEDIATED TROPONIN-T GENE-TRANSFER AND EXPRESSION IN ADULT CARDIAC MYOCYTES

      Biophysical journal
    40. WAHR PA; CANTOR HC; METZGER JM
      NUCLEOTIDE-DEPENDENT CONTRACTILE PROPERTIES OF CA2-ACTIVATED FAST ANDSLOW SKELETAL-MUSCLE FIBERS()

      Biophysical journal
    41. WESTFALL MV; SAMUELSON LC; METZGER JM
      TROPONIN-I ISOFORM EXPRESSION IS DEVELOPMENTALLY-REGULATED IN DIFFERENTIATING EMBRYONIC STEM CELL-DERIVED CARDIAC MYOCYTES

      Developmental dynamics
    42. METZGER JM
      PH-DEPENDENCE OF MYOSIN BINDING-INDUCED ACTIVATION OF THE THIN FILAMENT IN CARDIAC MYOCYTES AND SKELETAL FIBERS

      American journal of physiology. Heart and circulatory physiology
    43. METZGER JM
      EFFECTS OF TROPONIN-C ISOFORMS ON PH SENSITIVITY OF CONTRACTION IN MAMMALIAN FAST AND SLOW SKELETAL-MUSCLE FIBERS

      Journal of physiology
    44. HALE JJ; MILLS SG; MACCOSS M; SHAH SK; QI HB; MATHRE DJ; CASCIERI MA; SADOWSKI S; STRADER CD; MACINTYRE DE; METZGER JM
      NYL-4-((3-OXO-1,2,4-TRIAZOL-5-YL)METHYL)MORPHOLINE .1. A POTENT, ORALLY-ACTIVE, MORPHOLINE-BASED HUMAN NEUROKININ-1 RECEPTOR ANTAGONIST

      Journal of medicinal chemistry
    45. LADDUWAHETTY T; BAKER R; CASCIERI MA; CHAMBERS MS; HAWORTH K; KEOWN LE; MACINTYRE DE; METZGER JM; OWEN S; RYCROFT W; SADOWSKI S; SEWARD EM; SHEPHEARD SL; SWAIN CJ; TATTERSALL FD; WATT AP; WILLIAMSON DW; HARGREAVES RJ
      N-HETEROARYL-2-PHENYL-3-(BENZYLOXY)PIPERIDINES - A NOVEL CLASS OF POTENT ORALLY-ACTIVE HUMAN NK1 ANTAGONISTS

      Journal of medicinal chemistry
    46. METZGER JM; LIN WI; SAMUELSON LC
      VITAL STAINING OF CARDIAC MYOCYTES DURING EMBRYONIC STEM-CELL CARDIOGENESIS IN-VITRO

      Circulation research
    47. WAHR PA; METZGER JM
      THE EFFECTS OF CTP ON KINETICS OF CONTRACTION IN SKINNED FAST AND SLOW SKELETAL-MUSCLE FIBERS

      Biophysical journal
    48. METZGER JM; WAHR PA
      EFFECTS ON CROSS-BRIDGE INTERACTION WITH ACTIN DUE TO ACIDIC PH IN SINGLE CARDIAC MYOCYTES

      Biophysical journal
    49. WESTFALL MV; YULE DI; PASYK K; SAMUELSON LC; METZGER JM
      ULTRASTRUCTURAL CHARACTERIZATION OF CARDIAC MYOCYTES DERIVED FROM DIFFERENTIATING EMBRYONIC STEM-CELLS

      Biophysical journal
    50. RUST EM; WESTFALL MV; JOHNSTON R; LEE N; METZGER JM
      EFFICIENT GENE-TRANSFER INTO PRIMARY VENTRICULAR MYOCYTES MEDIATED BYRECOMBINANT ADENOVIRUS

      Biophysical journal
    51. METZGER JM
      EFFECTS OF PHOSPHATE AND ADP ON SHORTENING VELOCITY DURING MAXIMAL AND SUBMAXIMAL CALCIUM ACTIVATION OF THE THIN FILAMENT IN SKELETAL-MUSCLE FIBERS

      Biophysical journal
    52. METZGER JM
      EFFECTS ON CA2-ACTIVATED TENSION DUE TO A SYNTHETIC NH2-TERMINAL ACTIN PEPTIDE IN SINGLE SKELETAL-MUSCLE FIBERS()

      American journal of physiology. Cell physiology
    53. METZGER JM; RUDNICKI MA; WESTFALL MV
      ALTERED CA2-MUSCLE FIBERS FROM MYOD GENE-INACTIVATED MICE( SENSITIVITY OF TENSION IN SINGLE SKELETAL)

      Journal of physiology
    54. MACLEOD AM; CASCIERI MA; MERCHANT KJ; SADOWSKI S; HARDWICKE S; LEWIS RT; MACINTYRE DE; METZGER JM; FONG TM; SHEPHEARD S; TATTERSALL FD; HARGREAVES R; BAKER R
      SYNTHESIS AND BIOLOGICAL EVALUATION OF NK1 ANTAGONISTS DERIVED FROM L-TRYPTOPHAN

      Journal of medicinal chemistry
    55. METZGER JM; LIN WI; JOHNSTON RA; WESTFALL MV; SAMUELSON LC
      MYOSIN HEAVY-CHAIN EXPRESSION IN CONTRACTING MYOCYTES ISOLATED DURINGEMBRYONIC STEM-CELL CARDIOGENESIS

      Circulation research
    56. METZGER JM
      MYOSIN BINDING-INDUCED COOPERATIVE ACTIVATION OF THE THIN FILAMENT INCARDIAC MYOCYTES AND SKELETAL-MUSCLE FIBERS

      Biophysical journal
    57. METZGER JM; RUDNICKI MA; WESTFALL MV; LIN WI; JAENISCH R
      SKELETAL-MUSCLE CONTRACTILE PHENOTYPE IN MYOD-GENE INACTIVATED MICE

      Journal of cellular biochemistry
    58. MACLEOD M; MERCHANT KJ; BROOKFIELD F; KELLEHER F; STEVENSON G; OWENS AP; SWAIN CJ; BAKER R; CASCIERI MA; SADOWSKI S; BER E; STRADER CD; MACINTYRE DE; METZGER JM; BALL RG
      IDENTIFICATION OF L-TRYPTOPHAN DERIVATIVES WITH POTENT AND SELECTIVE ANTAGONIST ACTIVITY AT THE NK1 RECEPTOR

      Journal of medicinal chemistry
    59. METZGER JM; LIN WI; SAMUELSON LC
      TRANSITION IN CARDIAC CONTRACTILE SENSITIVITY TO CALCIUM DURING THE IN-VITRO DIFFERENTIATION OF MOUSE EMBRYONIC STEM-CELLS

      The Journal of cell biology
    60. METZGER JM; LIN WI; SAMUELSON LC
      CARDIAC MYOCYTE STRUCTURE AND FUNCTION DURING THE IN-VITRO DIFFERENTIATION OF MOUSE EMBRYONIC STEM-CELLS

      Biophysical journal
    61. METZGER JM; PARMACEK MS; BARR E; PASYK K; LIN WI; COCHRANE KL; FIELD LJ; LEIDEN JM
      SKELETAL TROPONIN-C REDUCES CONTRACTILE SENSITIVITY TO ACIDOSIS IN CARDIAC MYOCYTES FROM TRANSGENIC MICE

      Proceedings of the National Academy of Sciences of the United Statesof America
    62. DOHERTY JB; SHAH SK; FINKE PE; DORN CP; HAGMANN WK; HALE JJ; KISSINGER AL; THOMPSON KR; BRAUSE K; CHANDLER GO; KNIGHT WB; MAYCOCK AL; AHSE BM; WESTON H; GALE P; MUMFORD RA; ANDERSEN OF; WILLIAMS HR; NOLAN TE; FRANKENFIELD DL; UNDERWOOD D; VYAS KP; KARI PH; DAHLGREN ME; MAO J; FLETCHER DS; DELLEA PS; HAND KM; OSINGA DG; PETERSON LB; WILLIAMS DT; METZGER JM; BONNEY RJ; HUMES JL; PACHOLOK SP; HANLON WA; OPAS E; STOLK J; DAVIES P
      CHEMICAL, BIOCHEMICAL, PHARMACOKINETIC, AND BIOLOGICAL PROPERTIES OF L-680,833 - A POTENT, ORALLY-ACTIVE MONOCYCLIC BETA-LACTAM INHIBITOR OF HUMAN POLYMORPHONUCLEAR LEUKOCYTE ELASTASE

      Proceedings of the National Academy of Sciences of the United Statesof America


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Documento generato il 23/01/21 alle ore 21:02:30