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    1. Small, KM; Rathz, DA; Liggett, SB
      Identification of adrenergic receptor polymorphisms

      G PROTEIN PATHWAYS, PT A, RECEPTORS
    2. Liggett, SB
      Pharmacogenetic applications of the Human Genome Project

      NATURE MEDICINE
    3. McGraw, DW; Fukuda, N; James, PF; Forbes, SL; Woo, AL; Lingrel, JB; Witte, DP; Matthay, MA; Liggett, SB
      Targeted transgenic expression of beta(2)-adrenergic receptors to type II cells increases alveolar fluid clearance

      AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
    4. Israel, E; Drazen, JM; Liggett, SB; Boushey, HA; Cherniack, RM; Chinchilli, VM; Cooper, DM; Fahy, JV; Fish, JE; Ford, JG; Kraft, M; Kunselman, S; Lazarus, SC; Lemanske, RF; Martin, RJ; McLean, DE; Peters, SP; Silverman, EK; Sorkness, CA; Szefler, SJ; Weiss, ST; Yandava, CN
      Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma

      INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
    5. Liggett, SB
      beta-adrenergic receptors in the failing heart: the good, the bad, and theunknown

      JOURNAL OF CLINICAL INVESTIGATION
    6. Small, KM; Brown, KM; Forbes, SL; Liggett, SB
      Polymorphic deletion of three intracellular acidic residues of the alpha(2B)-adrenergic receptor decreases G protein-coupled receptor kinase-mediatedphosphorylation and desensitization

      JOURNAL OF BIOLOGICAL CHEMISTRY
    7. Small, KM; Brown, KM; Forbes, SL; Liggett, SB
      Modification of the beta(2)-adrenergic receptor to engineer a receptor-effector complex for gene therapy

      JOURNAL OF BIOLOGICAL CHEMISTRY
    8. Green, SA; Rathz, DA; Schuster, AJ; Liggett, SB
      The Ile164 beta(2)-adrenoceptor polymorphism alters salmeterol exosite binding and conventional agonist coupling to G(s)

      EUROPEAN JOURNAL OF PHARMACOLOGY
    9. Dash, R; Kadambi, VJ; Schmidt, AG; Tepe, NM; Biniakiewicz, D; Gerst, MJ; Canning, AM; Abraham, WT; Hoit, BD; Liggett, SB; Lorenz, JN; Dorn, GW; Kranias, EG
      Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality

      CIRCULATION
    10. Liang, M; Freedman, NJ; Theiss, CT; Liggett, SB
      Serine 232 of the alpha(2A)-adrenergic receptor is a protein kinase C-sensitive effector coupling switch

      BIOCHEMISTRY
    11. Small, KM; Liggett, SB
      Identification and functional characterization of alpha(2)-adrenoceptor polymorphisms

      TRENDS IN PHARMACOLOGICAL SCIENCES
    12. Tepe, NM; Liggett, SB
      Functional receptor coupling to G(i) is mechanism of agonist-promoted desensitization of the beta(2)-adrenergic receptor

      JOURNAL OF RECEPTOR AND SIGNAL TRANSDUCTION RESEARCH
    13. Israel, E; Drazen, JM; Liggett, SB; Boushey, HA; Cherniack, RM; Chinchilli, VM; Cooper, DM; Fahy, JV; Fish, JE; Ford, JG; Kraft, M; Kunselman, S; Lazarus, SC; Lemanske, RF; Martin, RJ; McLean, DE; Peters, SP; Silverman, EK; Sorkness, CA; Szefler, SJ; Weiss, ST; Yandava, CN
      The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    14. Liggett, SB
      beta(2)-Adrenergic receptor pharmacogenetics

      AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
    15. McGraw, DW; Forbes, SL; Mak, JCW; Witte, DP; Carrigan, PE; Leikauf, GD; Liggett, SB
      Transgenic overexpression of beta(2)-adrenergic receptors in airway epithelial cells decreases bronchoconstriction

      AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
    16. Yan, L; Galinsky, RE; Bernstein, JA; Liggett, SB; Weinshilboum, RM
      Histamine N-methyltransferase pharmacogenetics: association of a common functional polymorphism with asthma

      PHARMACOGENETICS
    17. Liggett, SB
      The pharmacogenetics of beta(2)-adrenergic receptors: Relevance to asthma

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    18. Liggett, SB
      Pharmacogenetics of beta-1-beta- and 2-adrenergic receptors

      PHARMACOLOGY
    19. Drysdale, CM; McGraw, DW; Stack, CB; Stephens, JC; Judson, RS; Nandabalan, K; Arnold, K; Ruano, G; Liggett, SB
      Complex promoter and coding region beta(2)-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    20. Dorn, GW; Tepe, NM; Wu, GY; Yatani, A; Liggett, SB
      Mechanisms of impaired beta-adrenergic receptor signaling in G(alpha q)-mediated cardiac hypertrophy and ventricular dysfunction

      MOLECULAR PHARMACOLOGY
    21. Small, KM; Forbes, SL; Brown, KM; Liggett, SB
      An Asn to Lys polymorphism in the third intracellular loop of the human alpha(2A)-adrenergic receptor imparts enhanced agonist-promoted G(i) coupling

      JOURNAL OF BIOLOGICAL CHEMISTRY
    22. Jewell-Motz, EA; Small, KM; Theiss, CT; Liggett, SB
      alpha(2A)/alpha(2C)-adrenergic receptor third loop chimera show that agonist interaction with receptor subtype backbone establishes G protein-coupledreceptor kinase phosphorylation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    23. Small, KM; Forbes, SL; Rahman, FF; Bridges, KM; Liggett, SB
      A four amino acid deletion polymorphism in the third intracellular loop ofthe human alpha(2C)-adrenergic receptor confers impaired coupling to multiple effectors

      JOURNAL OF BIOLOGICAL CHEMISTRY
    24. Wagoner, LE; Craft, LL; Singh, B; Suresh, DP; Zengel, PW; McGuire, N; Abraham, WT; Chenier, TC; Dorn, GW; Liggett, SB
      Polymorphisms of the beta(2)-adrenergic receptor determine exercise capacity in patients with heart failure

      CIRCULATION RESEARCH
    25. Liggett, SB; Tepe, NM; Lorenz, JN; Canning, AM; Jantz, TD; Mitarai, S; Yatani, A; Dorn, GW
      Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts - Critical role for expression level

      CIRCULATION
    26. Small, KM; Forbes, SL; Rahman, FF; Liggett, SB
      Fusion of beta(2)-adrenergic receptor to G(alpha s) in mammalian cells: Identification of a specific signal transduction species not characteristic of constitutive activation or precoupling

      BIOCHEMISTRY
    27. Hoit, BD; Suresh, DP; Craft, L; Walsh, RA; Liggett, SB
      beta(2)-Adrenergic receptor polymorphisms at amino acid 16 differentially influence agonist-stimulated blood pressure and peripheral blood flow in normal individuals

      AMERICAN HEART JOURNAL
    28. Liggett, SB
      Plastic adenylyl cyclase

      AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
    29. McGraw, DW; Liggett, SB
      Coding block and 5 ' leader cistron polymorphisms of the beta(2)-adrenergic receptor

      CLINICAL AND EXPERIMENTAL ALLERGY
    30. Liggett, SB
      Molecular and genetic basis of beta(2)-adrenergic receptor function

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    31. Dorn, GW; Tepe, NM; Lorenz, JN; Koch, WJ; Liggett, SB
      Low- and high-level transgenic expression of beta(2)-adrenergic receptors differentially affect cardiac hypertrophy and function in G alpha q-overexpressing mice

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    32. McGraw, DW; Forbes, SL; Kramer, LA; Witte, DP; Fortner, CN; Paul, RJ; Liggett, SB
      Transgenic overexpression of beta(2)-adrenergic receptors in airway smoothmuscle alters myocyte function and ablates bronchial hyperreactivity

      JOURNAL OF BIOLOGICAL CHEMISTRY
    33. Small, K; Feng, JF; Lorenz, J; Donnelly, ET; Yu, A; Im, MJ; Dorn, GW; Liggett, SB
      Cardiac specific overexpression of transglutaminase II (G(h)) results in aunique hypertrophy phenotype independent of phospholipase C activation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    34. Mason, DA; Moore, JD; Green, SA; Liggett, SB
      A gain-of-function polymorphism in a G-protein coupling domain of the human beta(1)-adrenergic receptor

      JOURNAL OF BIOLOGICAL CHEMISTRY
    35. Tepe, NM; Liggett, SB
      Transgenic replacement of type V adenylyl cyclase identifies a critical mechanism of beta-adrenergic receptor dysfunction in the G(alpha q) overexpressing mouse

      FEBS LETTERS
    36. Tepe, NM; Lorenz, JN; Yatani, A; Dash, R; Kranias, EG; Dorn, GW; Liggett, SB
      Altering the receptor-effector ratio by transgenic overexpression of type V adenylyl cyclase: Enhanced basal catalytic activity and function without increased cardiomyocyte beta-adrenergic signalling

      BIOCHEMISTRY
    37. SURESH DP; CRAFT L; LIGGETT SB; WALSH RA; HOLT BD
      A BETA(2) RECEPTOR POLYMORPHISM INFLUENCES AGONIST-STIMULATED PERIPHERAL-BLOOD FLOW IN NORMAL INDIVIDUALS

      Journal of investigative medicine
    38. WEIR TD; MALLEK N; SANDFORD AJ; BAI TR; AWADH N; FITZGERALD JM; COCKCROFT D; JAMES A; LIGGETT SB; PARE PD
      BETA(2)-ADRENERGIC RECEPTOR HAPLOTYPES IN MILD, MODERATE AND FATAL NEAR-FATAL ASTHMA

      American journal of respiratory and critical care medicine
    39. LIGGETT SB
      PHARMACOGENETICS OF RELEVANT TARGETS IN ASTHMA

      Clinical and experimental allergy
    40. MCGRAW DW; DONNELLY ET; EASON MG; GREEN SA; LIGGETT SB
      ROLE OF BETA-ARK IN LONG-TERM AGONIST-PROMOTED DESENSITIZATION OF THEBETA(2)-ADRENERGIC RECEPTOR

      Cellular signalling
    41. SAKATA Y; HOIT BD; LIGGETT SB; WALSH RA; DORN GW
      FAILURE OF PRESSURE-OVERLOAD HYPERTROPHY IN G-ALPHA-Q OVEREXPRESSING MICE

      Journal of the American College of Cardiology
    42. ADAMS JW; SAKATA Y; DAVIS MG; SAH VP; WANG YB; LIGGETT SB; CHIEN KR; BROWN JH; DORN GW
      ENHANCED G-ALPHA-Q SIGNALING - A COMMON PATHWAY MEDIATES CARDIAC-HYPERTROPHY AND APOPTOTIC HEART-FAILURE

      Proceedings of the National Academy of Sciences of the United Statesof America
    43. LIANG M; EASON MG; JEWELLMOTZ EA; WILLIAMS MA; THEISS CT; DORN GW; LIGGETT SB
      PHOSPHORYLATION AND FUNCTIONAL DESENSITIZATION OF THE ALPHA(2A)-ADRENERGIC RECEPTOR BY PROTEIN-KINASE-C

      Molecular pharmacology
    44. LIGGETT SB; WAGONER LE; CRAFT LL; HORNUNG RW; HOIT BD; MCINTOSH TC; WALSH RA
      THE ILE164 BETA(2)-ADRENERGIC RECEPTOR POLYMORPHISM ADVERSELY AFFECTSTHE OUTCOME OF CONGESTIVE-HEART-FAILURE

      The Journal of clinical investigation
    45. McGraw, DW; Forbes, SL; Kramer, LA; Liggett, SB
      Polymorphisms of the 5 ' leader cistron of the human beta(2)-adrenergic receptor regulate receptor expression

      JOURNAL OF CLINICAL INVESTIGATION
    46. SURESH DP; CRAFT L; LIGGETT SB; WALSH RA; HOLT BD
      A BETA(2) RECEPTOR POLYMORPHISM INFLUENCES AGONIST-STIMULATED PERIPHERAL-BLOOD FLOW IN NORMAL INDIVIDUALS

      Circulation
    47. SAKATA Y; HOIT BD; LIGGETT SB; WALSH RA; DORN G
      DECOMPENSATION OF PRESSURE-OVERLOAD HYPERTROPHY IN G-ALPHA-Q-OVEREXPRESSING MICE

      Circulation
    48. SAKO H; DORN GW; LIGGETT SB; YATANI A
      ALTERATIONS OF CA2-AR RESPONSES IN FALLING HEART INDUCED BY CARDIAC-SPECIFIC OVEREXPRESSION OF G-ALPHA-Q( CURRENTS AND BETA)

      Biophysical journal
    49. JEWELLMOTZ EA; DONNELLY ET; EASON MG; LIGGETT SB
      AGONIST-MEDIATED DOWN-REGULATION OF G(ALPHA-I) VIA THE ALPHA(2)-ADRENERGIC RECEPTOR IS TARGETED BY RECEPTOR-G(I) INTERACTION AND IS INDEPENDENT OF RECEPTOR SIGNALING AND REGULATION

      Biochemistry (Easton)
    50. LIGGETT SB
      POLYMORPHISMS OF THE BETA(2)-ADRENERGIC RECEPTOR AND ASTHMA

      American journal of respiratory and critical care medicine
    51. KISS E; EDES I; SATO Y; LUO W; LIGGETT SB; KRANIAS EG
      BETA-ADRENERGIC REGULATION OF CAMP AND PROTEIN-PHOSPHORYLATION IN PHOSPHOLAMBAN-KNOCKOUT MOUSE HEARTS

      American journal of physiology. Heart and circulatory physiology
    52. DEWAR JC; WILKINSON J; WHEATLEY A; THOMAS NS; DOULL I; MORTON N; LIO P; HARVEY JF; LIGGETT SB; HOLGATE ST; HALL IP
      THE GLUTAMINE-27 BETA(2)-ADRENOCEPTOR POLYMORPHISM IS ASSOCIATED WITHELEVATED IGE LEVELS IN ASTHMATIC FAMILIES

      Journal of allergy and clinical immunology
    53. DANGELO DD; SAKATA Y; LORENZ JN; BOIVIN GP; WALSH RA; LIGGETT SB; DORN GW
      TRANSGENIC G-ALPHA-Q OVEREXPRESSION INDUCES CARDIAC CONTRACTILE FAILURE IN MICE

      Proceedings of the National Academy of Sciences of the United Statesof America
    54. MCGRAW DW; LIGGETT SB
      HETEROGENEITY IN BETA-ADRENERGIC-RECEPTOR KINASE EXPRESSION IN THE LUNG ACCOUNTS FOR CELL-SPECIFIC DESENSITIZATION OF THE BETA(2)-ADRENERGIC RECEPTOR

      The Journal of biological chemistry
    55. WAGONER LE; HOIT BD; HORNUNG RW; CRAFT LL; WALSH RA; LIGGETT SB
      GENETIC POLYMORPHISMS OF THE HUMAN BETA(2) ADRENERGIC-RECEPTOR (BETA-2AR) PREDICT SURVIVAL IN PATIENTS WITH HEART-FAILURE

      Circulation
    56. HOIT BD; KHOURY SF; SHAO YF; GABEL M; LIGGETT SB; WALSH RA
      EFFECTS OF THYROID-HORMONE ON CARDIAC BETA-ADRENERGIC RESPONSIVENESS IN CONSCIOUS BABOONS

      Circulation
    57. JEWELLMOTZ EA; DONNELLY ET; EASON MG; LIGGETT SB
      ROLE OF THE AMINO-TERMINUS OF THE 3RD INTRACELLULAR LOOP IN AGONIST-PROMOTED DOWN-REGULATION OF THE ALPHA(2A)-ADRENERGIC RECEPTOR

      Biochemistry
    58. DORN GW; OSWALD KJ; MCCLUSKEY TS; KUHEL DG; LIGGETT SB
      ALPHA-2A-ADRENERGIC RECEPTOR-STIMULATED CALCIUM-RELEASE IS TRANSDUCEDBY G(I)-ASSOCIATED G-BETA-GAMMA-MEDIATED ACTIVATION OF PHOSPHOLIPASE-C

      Biochemistry
    59. YANDAVA CN; COOPER DM; PILLARI A; LIGGETT SB; DRAZEN JM
      MUTATION DETECTION METHODS AND PREFERENTIAL AMPLIFICATION OF WILD-TYPE ALLELE OF THE HUMAN BETA(2)-ADRENERGIC RECEPTOR GENE

      American journal of human genetics
    60. WAGONER LE; HOIT BD; HEDGER VH; DONNELLY E; BHAT G; WALSH RA; LIGGETT SB
      POLYMORPHISMS OF THE BETA(2) ADRENERGIC-RECEPTOR (BETA(2)AR) AFFECT EXERCISE CAPACITY IN PATIENTS WITH HEART-FAILURE

      Journal of investigative medicine
    61. TURKI J; LORENZ JN; GREEN SA; DONNELLY ET; JACINTO M; LIGGETT SB
      MYOCARDIAL SIGNALING DEFECTS AND IMPAIRED CARDIAC-FUNCTION OF A HUMANBETA(2)-ADRENERGIC RECEPTOR POLYMORPHISM EXPRESSED IN TRANSGENIC MICE

      Proceedings of the National Academy of Sciences of the United Statesof America
    62. GREEN SA; SPASOFF AP; COLEMAN RA; JOHNSON M; LIGGETT SB
      SUSTAINED ACTIVATION OF A G-PROTEIN-COUPLED RECEPTOR VIA ANCHORED AGONIST BINDING - MOLECULAR LOCALIZATION OF THE SALMETEROL EXOSITE WITHINTHE BETA(2)-ADRENERGIC RECEPTOR

      The Journal of biological chemistry
    63. JEWELLMOTZ EA; LIGGETT SB
      G-PROTEIN-COUPLED RECEPTOR KINASE SPECIFICITY FOR PHOSPHORYLATION ANDDESENSITIZATION OF ALPHA(2)-ADRENERGIC RECEPTOR SUBTYPES

      The Journal of biological chemistry
    64. EASON MG; LIGGETT SB
      CHIMERIC MUTAGENESIS OF PUTATIVE G-PROTEIN COUPLING DOMAINS OF THE ALPHA(2A)-ADRENERGIC RECEPTOR - LOCALIZATION OF 2 REDUNDANT AND FULLY COMPETENT G(1) COUPLING DOMAINS

      The Journal of biological chemistry
    65. WAGONER LE; HOIT BD; HEDGER VH; DONNELLY E; BHAT G; WALSH RA; LIGGETT SB
      POLYMORPHISMS OF THE BETA(2) ADRENERGIC-RECEPTOR (BETA(2)AR) AFFECT EXERCISE CAPACITY IN PATIENTS WITH HEART-FAILURE

      Circulation
    66. LIGGETT SB; LEVI R; METZGER H
      G-PROTEIN COUPLED RECEPTORS, NITRIC-OXIDE, AND THE IGE RECEPTOR IN ASTHMA

      American journal of respiratory and critical care medicine
    67. GREEN SA; TURKI J; BEJARANO P; HALL IP; LIGGETT SB
      INFLUENCE OF BETA(2)-ADRENERGIC RECEPTOR GENOTYPES ON SIGNAL-TRANSDUCTION IN HUMAN AIRWAY SMOOTH-MUSCLE CELLS

      American journal of respiratory cell and molecular biology
    68. TURKI J; LIGGETT SB
      RECEPTOR-SPECIFIC FUNCTIONAL-PROPERTIES OF BETA(2)-ADRENERGIC RECEPTOR AUTOANTIBODIES IN ASTHMA

      American journal of respiratory cell and molecular biology
    69. TURKI J; GREEN SA; NEWMAN KB; MEYERS MA; LIGGETT SB
      HUMAN LUNG-CELL BETA(2)-ADRENERGIC RECEPTORS DESENSITIZE IN RESPONSE TO IN-VIVO ADMINISTERED BETA-AGONIST

      American journal of physiology. Lung cellular and molecular physiology
    70. LIGGETT SB
      GENETICS OF BETA(2)-ADRENERGIC RECEPTOR VARIANTS IN ASTHMA

      Clinical and experimental allergy
    71. EASON MG; MOREIRA SP; LIGGETT SB
      4 CONSECUTIVE SERINES IN THE 3RD INTRACELLULAR LOOP ARE THE SITES FORBETA-ARK PHOSPHORYLATION AND DESENSITIZATION OF THE ALPHA(2A)-ADRENERGIC RECEPTOR

      The FASEB journal
    72. JEWELLMOTZ EA; LIGGETT SB
      A UNIQUE ACIDIC MOTIF WITHIN THE 3RD INTRACELLULAR LOOP OF THE ALPHA(2)C2 ADRENERGIC-RECEPTOR IS REQUIRED FOR AGONIST-PROMOTED PHOSPHORYLATION AND DESENSITIZATION

      The FASEB journal
    73. HALL IP; WHEATLEY A; WILDING P; LIGGETT SB
      ASSOCIATION OF GLU-27 BETA(2)-ADRENOCEPTOR POLYMORPHISM WITH LOWER AIRWAY REACTIVITY IN ASTHMATIC SUBJECTS

      Lancet
    74. TURKI J; PAK J; GREEN SA; MARTIN RJ; LIGGETT SB
      GENETIC POLYMORPHISMS OF THE BETA(2)-ADRENERGIC RECEPTOR IN NOCTURNALAND NONNOCTURNAL ASTHMA - EVIDENCE THAT GLY16 CORRELATES WITH THE NOCTURNAL PHENOTYPE

      The Journal of clinical investigation
    75. EASON MG; MOREIRA SP; LIGGETT SB
      4 CONSECUTIVE SERINES IN THE 3RD INTRACELLULAR LOOP ARE THE SITES FORBETA-ADRENERGIC-RECEPTOR KINASE-MEDIATED PHOSPHORYLATION AND DESENSITIZATION OF THE ALPHA(2A)-ADRENERGIC RECEPTOR

      The Journal of biological chemistry
    76. EASON MG; LIGGETT SB
      IDENTIFICATION OF A G(S) COUPLING DOMAIN IN THE AMINO-TERMINUS OF THE3RD INTRACELLULAR LOOP OF THE ALPHA(2A)-ADRENERGIC RECEPTOR - EVIDENCE FOR DISTINCT STRUCTURAL DETERMINANTS THAT CONFER G(S) VERSUS G(I) COUPLING

      The Journal of biological chemistry
    77. FREEDMAN NJ; LIGGETT SB; DRACHMAN DE; PEI G; CARON MG; LEFKOWITZ RJ
      PHOSPHORYLATION AND DESENSITIZATION OF THE HUMAN BETA(1)-ADRENERGIC RECEPTOR - INVOLVEMENT OF G-PROTEIN-COUPLED RECEPTOR KINASES AND CAMP-DEPENDENT PROTEIN-KINASE

      The Journal of biological chemistry
    78. KHOURY SF; HOIT BD; SHAO YF; GABEL M; LIGGETT SB; WALSH RA
      DIFFERENTIAL CARDIAC BETA-ADRENERGIC SUBTYPE DENSITY AND THE SENSITIVITY OF LEFT-VENTRICULAR FUNCTION TO CATECHOLAMINES IN THYROTOXIC BABOONS

      Circulation
    79. JEWELLMOTZ EA; LIGGETT SB
      AN ACIDIC MOTIF WITHIN THE 3RD INTRACELLULAR LOOP OF THE ALPHA(2)C2 ADRENERGIC-RECEPTOR IS REQUIRED FOR AGONIST-PROMOTED PHOSPHORYLATION AND DESENSITIZATION

      Biochemistry
    80. EASON MG; JACINTO MT; THEISS CT; LIGGETT SB
      THE PALMITOYLATED CYSTEINE OF THE CYTOPLASMIC TAIL OF ALPHA(2A)-ADRENERGIC RECEPTORS CONFERS SUBTYPE-SPECIFIC AGONIST-PROMOTED DOWN-REGULATION

      Proceedings of the National Academy of Sciences of the United Statesof America
    81. EASON MG; JACINTO MT; LIGGETT SB
      CONTRIBUTION OF LIGAND STRUCTURE TO ACTIVATION OF ALPHA(2)-ADRENERGICRECEPTOR SUBTYPE COUPLING TO G(S)

      Molecular pharmacology
    82. GREEN SA; LIGGETT SB
      A PROLINE-RICH REGION OF THE 3RD INTRACELLULAR LOOP IMPARTS PHENOTYPIC BETA(1)-VERSUS BETA(2)-ADRENERGIC RECEPTOR COUPLING AND SEQUESTRATION

      The Journal of biological chemistry
    83. FREEDMAN NJ; DRACHMAN D; LIGGETT SB; LEFKOWITZ RJ
      DESENSITIZATION OF THE BETA-ADRENERGIC-RECEPTOR BY RECEPTOR-SPECIFIC KINASES

      Circulation
    84. FREEDMAN NJ; DRACHMAN D; LIGGETT SB; LEFKOWITZ RJ
      DESENSITIZATION OF THE BETA-ADRENERGIC-RECEPTOR BY RECEPTOR-SPECIFIC KINASES

      Circulation
    85. GREEN SA; TURKI J; INNIS M; LIGGETT SB
      AMINO-TERMINAL POLYMORPHISMS OF THE HUMAN BETA(2)-ADRENERGIC RECEPTORIMPART DISTINCT AGONIST-PROMOTED REGULATORY PROPERTIES (VOL 33, PG 9414, 1994)

      Biochemistry
    86. GREEN SA; TURKI J; INNIS M; LIGGETT SB
      AMINO-TERMINAL POLYMORPHISMS OF THE HUMAN BETA(2)-ADRENERGIC RECEPTORIMPART DISTINCT AGONIST-PROMOTED REGULATORY PROPERTIES

      Biochemistry
    87. REIHSAUS E; INNIS M; MACINTYRE N; LIGGETT SB
      MUTATIONS IN THE GENE ENCODING FOR THE BETA-2-ADRENERGIC RECEPTOR IN NORMAL AND ASTHMATIC SUBJECTS

      American journal of respiratory cell and molecular biology
    88. LIGGETT SB; RAYMOND JR
      PHARMACOLOGY AND MOLECULAR-BIOLOGY OF ADRENERGIC-RECEPTORS

      Bailliere's clinical endocrinology and metabolism
    89. LIGGETT SB; FREEDMAN NJ; SCHWINN DA; LEFKOWITZ RJ
      STRUCTURAL BASIS FOR RECEPTOR SUBTYPE-SPECIFIC REGULATION REVEALED BYA CHIMERIC-BETA(3) BETA(2)-ADRENERGIC RECEPTOR/

      Proceedings of the National Academy of Sciences of the United Statesof America
    90. EASON MG; LIGGETT SB
      HUMAN ALPHA(2)-ADRENERGIC RECEPTOR SUBTYPE DISTRIBUTION - WIDESPREAD AND SUBTYPE-SELECTIVE EXPRESSION OF ALPHA(2) C10, ALPHA(2) C4, AND ALPHA(2) C2 MESSENGER-RNA IN MULTIPLE TISSUES

      Molecular pharmacology
    91. GREEN SA; COLE G; JACINTO M; INNIS M; LIGGETT SB
      A POLYMORPHISM OF THE HUMAN BETA(2)-ADRENERGIC RECEPTOR WITHIN THE 4TH TRANSMEMBRANE DOMAIN ALTERS LIGAND-BINDING AND FUNCTIONAL-PROPERTIESOF THE RECEPTOR

      The Journal of biological chemistry
    92. EASON MG; LIGGETT SB
      FUNCTIONAL ALPHA(2)-ADRENERGIC RECEPTOR-GS COUPLING UNDERGOES AGONIST-PROMOTED DESENSITIZATION IN A SUBTYPE-SELECTIVE MANNER

      Biochemical and biophysical research communications
    93. LIGGETT SB
      MUTATIONS OF THE GENE ENCODING FOR THE BETA(2)-ADRENERGIC RECEPTOR INNORMAL AND ASTHMATIC-PATIENTS

      The American review of respiratory disease
    94. LIGGETT SB
      MUTATIONS OF THE GENE ENCODING FOR THE BETA-2-ADRENERGIC RECEPTOR IN NORMAL AND ASTHMATIC-PATIENTS

      The American review of respiratory disease


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Documento generato il 21/01/20 alle ore 00:51:07