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    1. Naimi, E; Duan, WL; Wiebe, LI; Knaus, EE
      Synthesis of unnatural 7-substituted-1-(2-deoxy-beta-D-ribofuranosyl)isocarbostyrils: "Thymine replacement" analogs of deoxythymidine for evaluation as antiviral and anticancer agents

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    2. Wang, ZX; Duan, WL; Wiebe, LI; Balzarini, J; De Clercq, E; Knaus, EE
      Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzene thymidine mimics, some related alpha-anomers, and their evaluation as antiviral and anticancer agents

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    3. Wang, ZX; Duan, WL; Wiebe, LI; Balzarini, J; De Clercq, E; Knaus, EE
      Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzenes: "Thymine replacement" analogs of thymidine for evaluation as anticancer and antiviral agents

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    4. Naimi, E; Wiebe, LI; Balzarini, J; De Clercq, E; Knaus, EE
      Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-(2-halo-1-hydroxyethyl)benzenes and related derivatives: "Thymine replacement" analogs of deoxythymidine for evaluation as antiviral and anticancer agents

      DRUG DEVELOPMENT RESEARCH
    5. Mark, BL; Parrish, JC; Wang, ZX; Wiebe, LI; Knaus, EE; James, MNG
      (E)-1-(2 '-Deoxy-beta-D-ribofuranosyl)2,4-difluoro-5-(2-iodovinyl)benzene

      ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
    6. Habeeb, AG; Rao, PNP; Knaus, EE
      Design and synthesis of 4,5-diphenyl-4-isoxazolines: Novel inhibitors of cyclooxygenase-2 with analgesic and antiinflammatory activity

      JOURNAL OF MEDICINAL CHEMISTRY
    7. Habeeb, AG; Rao, PNP; Knaus, EE
      Design and synthesis of celecoxib and rofecoxib analogues as selective cyclooxygenase-2 (COX-2) inhibitors: Replacement of sulfonamide and methylsulfonyl pharmacophores by an azido bioisostere

      JOURNAL OF MEDICINAL CHEMISTRY
    8. Wang, ZX; Duan, WL; Wiebe, LI; De Clercq, E; Balzarini, J; Knaus, EE
      Syntheses of 1-[(2-hydroxyethoxy)methyl]- and 1-[(1,3-dihydroxy-2-propoxy)methyl]-derivatives of 5-substituted-2,4-difluorobenzene: Unnatural acyclo thymidine mimics for evaluation as anticancer and antiviral agents

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    9. Parang, K; Wiebe, LI; Knaus, EE
      Novel approaches for designing 5 '-O-ester prodrugs of 3'-azido-2 ',3 '-dideoxythymidine (AZT)

      CURRENT MEDICINAL CHEMISTRY
    10. Iqbal, N; McEwen, CA; Sardari, S; Daneshtalab, M; Knaus, EE
      Evaluation of methylthio-, methylsulfinyl-, and methylsulfonyl-analogs of alkanes and alkanoic acids as cardiac inotropic and antifungal agents

      ARCHIV DER PHARMAZIE
    11. Miri, R; McEwen, CA; Knaus, EE
      Synthesis and calcium channel modulating effects of modified Hantzsch nitrooxyalkyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-(pyridinyl or 2-trifluoromethylphenyl)-5-pyridinecarboxylates

      DRUG DEVELOPMENT RESEARCH
    12. Nguyen, JT; McEwen, CA; Knaus, EE
      Hantzsch 1,4-dihydropyridines containing a nitrooxyalkyl ester moiety to study calcium channel antagonist structure-activity relationships and nitricoxide release

      DRUG DEVELOPMENT RESEARCH
    13. Habeeb, AG; Rao, PNP; Knaus, EE
      Design and syntheses of diarylisoxazoles: Novel inhibitors of cyclooxygenase-2 (COX-2) with analgesic-antiinflammatory activity

      DRUG DEVELOPMENT RESEARCH
    14. Iqbal, N; McEwen, CA; Knaus, EE
      Synthesis and calcium channel modulation effects of isopropyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-phenylpyridine-5-carboxylates possessing ortho-, meta-, and para-CH2S(O)nMe and -S(O)nMe (n=0-2) phenyl substituents

      DRUG DEVELOPMENT RESEARCH
    15. Ramesh, M; Matowe, WC; Wolowyk, MW; Knaus, EE
      Design and syntheses of C-4 4-(1-methoxycarbonyl-1,2-dihydropyridyl)-, and3-[1-methoxycarbonyl-1,2-(and 1,6-)dihydropyridyl]-, derivatives of alkyl 1,4-dihydro-2,6-dimethyl-3-nitro-5-pyridinecarboxylates with cardiospecificcalcium channel agonist activity

      DRUG DEVELOPMENT RESEARCH
    16. Agudoawu, S; Li, HY; Habeeb, AG; Rao, PNP; Suresh, MR; Knaus, EE
      Design and syntheses of methyl 2-methyl-2-[2-(4-benzoyl-5-phenyl-7-halo-2-azabicyclo[4.1.0]hept-3-ene)]acetates: Novel inhibitors of cyclooxygenase-2(COX-2) with analgesic-antiinflammatory activity

      DRUG DEVELOPMENT RESEARCH
    17. Morin, KW; Knaus, EE; Wiebe, LI; Xia, H; McEwan, AJB
      Reporter gene imaging: Effects of ganciclovir treatment on nucleoside uptake, hypoxia and perfusion in a murine gene therapy tumour model that expresses herpes simplex type-1 thymidine kinase

      NUCLEAR MEDICINE COMMUNICATIONS
    18. Mazumdar, G; De, M; Mukhopadhyay, A; Mazumdar, SK; Mazumder, N; Das, AK; Knaus, EE
      Ethyl 3-(2 '-deoxyuridin-5-yl)-3-hydroxy-2-iodopropanoate, a nucleoside analogue

      ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
    19. Parrish, JC; Shan, R; Knaus, EE; James, MNG
      Racemic isopropyl 1,4-dihydro-2,6-dimethyl-4-(6-methyl-2-pyridyl)-3-nitropyridine-5-carboxylate hemibenzene solvate

      ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
    20. Wang, ZX; Wiebe, LI; Balzarini, J; De Clercq, E; Knaus, EE
      Chiral synthesis of 4-[1-(2-deoxy-beta-L-ribofuranosyl)] derivatives of 2-substituted 5-fluoroaniline: "Cytosine replacement" analogues of deoxy-beta-L-cytidine

      JOURNAL OF ORGANIC CHEMISTRY
    21. Agudoawu, SA; Knaus, EE
      Synthesis and analgesic-antiinflammatory activities of ethyl 2-[3-(1-phenoxy( methoxy)carbonyl-4-aryl-(alkyl)-1,4-dihydropyridyl)]acetates

      JOURNAL OF HETEROCYCLIC CHEMISTRY
    22. Wang, ZX; Wiebe, LI; De Clercq, E; Balzarini, J; Knaus, EE
      Syntheses of 4-[1-(2-deoxy-beta-D-ribofuranosyl)]-derivatives of 2-substituted-5-fluoroaniline: '' cytosine replacement '' analogs of deoxycytidine for evaluation as anticancer and antihuman immunodeficiency virus (anti-HIV)agents

      CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE
    23. Shan, RD; Knaus, EE
      The design of (-)-(S)-2-nitrooxyethyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylate: A cardioselective positive inotropic derivative of Bay K 8644

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    24. Wiebe, LI; Knaus, EE; Morin, KW
      Radiolabelled pyrimidine nucleosides to monitor the expression of HSV-1 thymidine kinase in gene therapy

      NUCLEOSIDES & NUCLEOTIDES
    25. Xia, ZP; Wiebe, LI; Miller, GG; Knaus, EE
      Synthesis and biological evaluation of butanoate, retinoate, and bis(2,2,2-trichloroethyl)phosphate derivatives of 5-fluoro-2 '-deoxyuridine and 2 ',5-difluoro-2 '-deoxyuridine as potential dual action anticancer prodrugs

      ARCHIV DER PHARMAZIE
    26. Agudoawu, SA; Yiu, SH; Wallace, JL; Knaus, EE
      Synthesis and analgesic activity of 2-methyl-2-[1-(3-benzoyl-4-substituted-1,4-dihydropyridyl)]acetic acid methyl esters, acetic acids, and acetamides

      ARCHIV DER PHARMAZIE
    27. Ramesh, M; Matowe, WC; Wolowyk, MW; Knaus, EE
      Synthesis and calcium channel antagonist activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-[4-(1-methoxycarbonyl-1,4-dihydropyridyl)]-3,5-pyridinedicarboxylates

      ARCHIV DER PHARMAZIE
    28. Yiu, SH; Knaus, EE
      Synthesis, calcium channel antagonist activity, and anticonvulsant activity of 3-ethyl 5-methyl 1,4-dihydro-2-[(2-hydroxyethoxy)methyl]6-methyl-4-(2,3-dichlorophenyl)-3,5-pyridinedicarboxylate coupled to a 1-methyl-1,4-dihydropyridyl-3-carbonyl chemical delivery system

      ARCHIV DER PHARMAZIE
    29. Yiu, SH; Knaus, EE
      Synthesis of valproate, valerate, and 1-methyl-1,4-dihydropyridyl-3-carbonyloxy ester derivatives of Hantzsch 1,4-dihydropyridines as potential prodrugs and their evaluation as calcium channel antagonist and anticonvulsant agents

      DRUG DEVELOPMENT RESEARCH
    30. Murthy, KSK; Knaus, EE
      Synthesis of pyrimido[1,4]diazepin-2-one analogs and their evaluation as anticonvulsant agents

      DRUG DEVELOPMENT RESEARCH
    31. Wiebe, LI; Knaus, EE
      Concepts for the design of anti-HIV nucleoside prodrugs for treating cephalic HIV infection

      ADVANCED DRUG DELIVERY REVIEWS
    32. Fiakpui, CY; Phillips, OA; Murthy, KSK; Knaus, EE
      Synthesis and anticonvulsant activities of 5-(2-chlorophenyl)-7H-pyrido[4,3-f][1,2,4]triazolo[4,3-a][1,4]diazepines

      JOURNAL OF HETEROCYCLIC CHEMISTRY
    33. Arora, VK; Knaus, EE
      Synthesis and anticonvulsant activity of 3-[3-[(dimethylamino)methyl]-5-methyl-4H-1,2,4-triazol-4-yl]-4-(o-chlorobenzoyl)pyridine

      JOURNAL OF HETEROCYCLIC CHEMISTRY
    34. Phillips, OA; Murthy, KSK; Fiakpui, CY; Knaus, EE
      Synthesis of 5-phenyl-10-methyl-7H-pyrimido[4,5-f][1,2,4]triazolo[4,3-a][1,4]diazepine and its evaluation as an anticonvulsant agent

      CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE
    35. PARANG K; WIEBE LI; KNAUS EE
      SYNTHESIS, IN-VITRO ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS STRUCTURE-ACTIVITY-RELATIONSHIPS AND BIOLOGICAL STABILITY OF 5'-O-MYRISTOYL ANALOG DERIVATIVES OF 3'-AZIDO-2',3'-DIDEOXYTHYMIDINE (AZT) AS POTENTIAL PRODRUGS

      Antiviral chemistry & chemotherapy
    36. PARANG K; KNAUS EE; WIEBE LI
      SYNTHESIS, IN-VITRO ANTI-HIV ACTIVITY, AND BIOLOGICAL STABILITY OF 5'-O-MYRISTOYL ANALOG DERIVATIVES OF 3'-FLUORO-2',3'-DIDEOXYTHYMIDINE (FLT) AS POTENTIAL BIFUNCTIONAL PRODRUGS OF FLT

      Nucleosides & nucleotides
    37. Parang, K; Wiebe, LI; Knaus, EE
      Pharmacokinetics and tissue distribution of (+/-)-3 '-azido-2 ',3 '-dideoxy-5 '-O-(2-bromomyristoyl)thymidine a prodrug of 3 '-azido-2 ',3 '-dideoxythymidine (AZT) in mice

      JOURNAL OF PHARMACY AND PHARMACOLOGY
    38. RAMESH M; MATOWE WC; AKULA MR; VO D; DAGNINO L; LIKWONGKEN MC; WOLOWYK MW; KNAUS EE
      SYNTHESIS AND CALCIUM CHANNEL-MODULATING EFFECTS OF ALKYL (OR CYCLOALKYL) 6-DIMETHYL-3-NITRO-4-PYRIDYL-5-PYRIDINECARBOXYLATE RACEMATES AND ENANTIOMERS

      Journal of medicinal chemistry
    39. IQBAL N; AKULA MR; VO D; MATOWE WC; MCEWEN CA; WOLOWYK MW; KNAUS EE
      SYNTHESIS, ROTAMER ORIENTATION, AND CALCIUM-CHANNEL MODULATION ACTIVITIES OF ALKYL AND 2-PHENETHYL 1,4-DIHYDRO-2,6-DIMETHYL-3-NITRO-4-(3- OR 6-SUBSTITUTED-2-PYRIDYL)-5-PYRIDINECARBOXYLATES

      Journal of medicinal chemistry
    40. DEGREVE B; ANDREI G; IZQUIERDO M; PIETTE J; MORIN K; KNAUS EE; WIEBE LI; BASRAH I; WALKER RT; DECLERCQ E; BALZARINI J
      VARICELLA-ZOSTER VIRUS THYMIDINE KINASE GENE AND ANTIHERPETIC PYRIMIDINE NUCLEOSIDE ANALOGS IN A COMBINED GENE CHEMOTHERAPY TREATMENT FOR CANCER/

      Gene therapy
    41. PARANG K; WIEBE LI; KNAUS EE
      SYNTHESES AND BIOLOGICAL EVALUATION OF 5'-O-MYRISTOYL DERIVATIVES OF THYMIDINE AGAINST HUMAN-IMMUNODEFICIENCY-VIRUS

      Antiviral chemistry & chemotherapy
    42. MIRI R; HOWLETT SE; KNAUS EE
      SYNTHESIS AND CALCIUM-CHANNEL MODULATING EFFECTS OF ISOPROPYL IMETHYL-3-NITRO-4-(THIENYL)-5-PYRIDINECARBOXYLATES

      Archiv der pharmazie
    43. KUMAR R; WIEBE LI; KNAUS EE
      SYNTHESIS AND ANTIVIRAL ACTIVITY OF -ETHYL-5-HALO-6-ALKOXY-5,6-DIHYDRO-2'-DEOXYURIDINE OR 5-ETHYL-5-HALO-6-AZIDO-5,6-DIHYDRO-2'-DEOXYURIDINE DIASTEREOMERS AS POTENTIAL PRODRUGS TO 5-ETHYL-2'-DEOXYURIDINE

      Archiv der pharmazie
    44. ANANA RD; NG H; HOWLETT SE; KNAUS EE
      SYNTHESIS AND SMOOTH-MUSCLE CALCIUM-CHANNEL EFFECTS OF DIALKYL DRO-2,6-DIMETHYL-4-ARYL-3,5-PYRIDINEDICARBOXYLATES CONTAINING A NITRONE MOIETY IN THE 4-ARYL SUBSTITUENT

      Archiv der pharmazie
    45. YIU SH; KNAUS EE
      SYNTHESES, CALCIUM-CHANNEL ANTAGONIST AND ANTICONVULSANT ACTIVITIES OF SUBSTITUTED 1,4-DIHYDRO-3,5-PYRIDINEDICARBOXYLATES CONTAINING VARIOUS 3-ALKYL ESTER SUBSTITUENTS

      Archiv der pharmazie
    46. IQBAL N; TRIGGLE CR; KNAUS EE
      NOVEL HANTZSCH 1,4-DIHYDROPYRIDINES TO STUDY THE STRUCTURE-FUNCTION-RELATIONSHIPS OF CALCIUM CHANNELS AND PHOTOINDUCED RELAXATION

      Drug development research
    47. PARANG K; WIEBE LI; KNAUS EE; HUANG JS; TYRRELL DL; CSIZMADIA F
      IN-VITRO ANTIVIRAL ACTIVITIES OF MYRISTIC ACID ANALOGS AGAINST HUMAN IMMUNODEFICIENCY AND HEPATITIS-B VIRUSES

      Antiviral research
    48. MORIN KW; KNAUS EE; WIEBE LI
      NONINVASIVE SCINTIGRAPHIC MONITORING OF GENE-EXPRESSION IN A HSV-1 THYMIDINE KINASE GENE-THERAPY MODEL

      Nuclear medicine communications
    49. MORIN KW; ATRAZHEVA ED; KNAUS EE; WIEBE LI
      SYNTHESIS AND CELLULAR UPTAKE OF 2'-SUBSTITUTED ANALOGS OF (E)-5-(2-[I-125]IODOVINYL)-2'-DEOXYURIDINE IN TUMOR-CELLS TRANSDUCED WITH THE HERPES-SIMPLEX TYPE-1 THYMIDINE KINASE GENE - EVALUATION AS PROBES FOR MONITORING GENE-THERAPY

      Journal of medicinal chemistry
    50. KUMAR R; WIEBE LI; KNAUS EE
      SYNTHESIS OF 5-(1-AZIDO-2-HALOETHYL)ARABINOURIDINES

      Journal of heterocyclic chemistry
    51. ANANA RD; KNAUS EE
      SYNTHESIS OF DIALKYL DIMETHYL-4-(HETEROARYL)PYRIDINE-3,5-DICARBOXYLATES AS CALCIUM-CHANNEL ANTAGONISTS

      Journal of heterocyclic chemistry
    52. AGUDOAWU SA; YIU SH; KNAUS EE
      SYNTHESIS OF -[1-(3-BENZOYL-4-PHENYL-1,4-DIHYDROPYRIDYL)]ACETIC ACID METHYL-ESTER, ACETIC-ACID, AND ACETAMIDE ANALOGS AS POTENTIAL ANTIARTHRITIC AGENTS

      Canadian journal of chemistry
    53. IQBAL N; WEI ZY; BAKER GB; KNAUS EE
      SYNTHESIS OF 4,4-BIS(2-METHYLPHENYL)-3-BUTENYL (AND BUTYL) ANALOGS OF4-PHENYL-1,4-DIHYDROPYRIDINE-3-CARBOXYLIC AND 6-PHENYL-1,6-DIHYDROPYRIDINE-3-CARBOXYLIC ACIDS AND THEIR EVALUATION AS NEURONAL GABA-UPTAKE INHIBITORS

      Canadian journal of chemistry
    54. KUMAR R; WANG LL; WIEBE LI; KNAUS EE
      SYNTHESIS, IN-VITRO BIOLOGICAL STABILITY, AND ANTI-HIV ACTIVITY OF 5-HALO (OR METHOXY)-6-ALKOXY (AZIDO OR ROXY)-5,6-DIHYDRO-2',3'-DIDEHYDRO-3'-DEOXYTHYMIDIN DIASTEREOMERS AS POTENTIAL PRODRUGS OF 2',3'-DIDEHYDRO-3'-DEOXYTHYMIDINE (D4T)

      Nucleosides & nucleotides
    55. ANANA RD; KNAUS EE
      SYNTHESIS AND SMOOTH-MUSCLE CALCIUM-CHANNEL ANTAGONIST EFFECTS OF ALKYL 4,4-DIMETHYLOXAZOLIN-2-YL)]-3-PYRIDINECARBOXYLATES

      Archiv der pharmazie
    56. PARANG K; KNAUS EE; WIEBE LI; SARDARI S; DANESHTALAB M; CSIZMADIA F
      SYNTHESIS AND ANTIFUNGAL ACTIVITIES OF MYRISTIC ACID ANALOGS

      Archiv der pharmazie
    57. IQBAL N; KNAUS EE
      SYNTHESIS AND SMOOTH-MUSCLE CALCIUM-CHANNEL ANTAGONIST EFFECTS OF DIALKYL DIHYDRO-2,6-DIMETHYL-4-ARYL-3,5-PYRIDINEDICARBOXYL CONTAINING A NITROOXY OR NITROPHENYL MOIETY IN THE 3-ALKYL ESTER SUBSTITUENT

      Archiv der pharmazie
    58. MINAKAWA N; MATSUDA A; XIA ZP; WIEBE LI; KNAUS EE
      SYNTHESES OF [2-H-2]-5-ETHYNYL-1-(BETA-D-RIDOFURANOSYL) IMIDAZOLE-4-CARBOXAMIDE AND -H-3]-BETA-D-RIBOFURANOSYL)IMIDAZOLE-4-CARBOXAMIDE (EICAR)

      Journal of labelled compounds & radiopharmaceuticals
    59. YIU SH; KNAUS EE
      AN IMPROVED SYNTHESIS OF HIGH-PURITY FELODIPINE

      Organic preparations and procedures international
    60. WANG LL; MORIN KW; KUMAR R; CHERAGHALI M; TODD KG; BAKER GB; KNAUS EE; WIEBE LI
      IN-VIVO BIODISTRIBUTION, PHARMACOKINETIC PARAMETERS, AND BRAIN UPTAKEOF O-6-METHOXY-5,6-DIHYDRO-3'-AZIDO-3'-DEOXYTHYMIDINE OR LO-6-ETHOXY-5,6-DIHYDRO-3'-AZIDO-3'-DEOXYTHYMIDINE DIASTEREOMERS AS POTENTIAL PRODRUGS OF 3'-AZIDO-3'-DEOXYTHYMIDINE

      Journal of medicinal chemistry
    61. YIU SH; KNAUS EE
      SYNTHESIS, BIOLOGICAL EVALUATION, CALCIUM-CHANNEL ANTAGONIST ACTIVITY, AND ANTICONVULSANT ACTIVITY OF FELODIPINE COUPLED TO A DIHYDROPYRIDINE-PYRIDINIUM SALT REDOX CHEMICAL DELIVERY SYSTEM

      Journal of medicinal chemistry
    62. IQBAL N; KNAUS EE
      SYNTHESIS OF 3-(2-GUANIDINOETHYL) AND 3-[2-(S-METHYLISOTHIOUREIDOETHYL)] ANALOGS OF 5-ISOPROPYL -4-(2,3-DICLOROROPHENYL)PYRIDINE-3,5-DICARBOXYLATE AS A RESPECTIVE RELEASER OF NITRIC-OXIDE AND INHIBITOR OF NITRIC-OXIDE SYNTHASE

      Journal of heterocyclic chemistry
    63. KUMAR R; WIEBE LI; KNAUS EE
      SYNTHESIS OF 5-(1-ARIDOVINYL) AND 5-[2-(1-AZIRINYL)] ANALOGS OF 2'-DEOXYURIDINE

      Canadian journal of chemistry
    64. LOVREN F; ONEILL SK; BIEGER D; IGBAL N; KNAUS EE; TRIGGLE CR
      NITRIC-OXIDE, A POSSIBLE MEDIATOR OF 1,4-DIHYDROPYRIDINE-INDUCED PHOTORELAXATION OF VASCULAR SMOOTH-MUSCLE

      British Journal of Pharmacology
    65. BALZARINI J; MORIN KW; KNAUS EE; WIEBE LI; DECLERCQ E
      NOVEL (E)-5-(2-IODOVINYL)-2'-DEOXYURIDINE DERIVATIVES AS POTENTIAL CYTOSTATIC AGENTS AGAINST HERPES-SIMPLEX VIRUS THYMIDINE KINASE GENE TRANSFECTED TUMORS

      Gene therapy
    66. CHERAGHALI AM; KUMAR R; MORIN KW; DECLERCQ E; KNAUS EE; WIEBE LI
      A COMPARATIVE-STUDY OF 5-ETHYL-2'-DEOXYURIDINE AND SELECTED LIPOPHILIC 5,6-DIHYDRO DOUBLE TRIPLE PRODRUGS

      Antiviral chemistry & chemotherapy
    67. WIEBE LI; KNAUS EE; CHERAGHALI AM; KUMAR R; MORIN KW; WANG L
      5-HALO-6-ALKOXY-5,6-DIHYDRO-PYRIMIDINE NUCLEOSIDES - ANTIVIRAL NUCLEOSIDES OR NUCLEOSIDE PRODRUGS

      Nucleosides & nucleotides
    68. IQBAL N; KNAUS EE
      SYNTHESIS AND CALCIUM-CHANNEL MODULATING EFFECTS OF ALKYL 1,4-DIHYDRO-2,6-DIMETHYL-4-(PYRIDINYL OR HENYL)-5-(1H-TETRAZOL-5-YL)-3-PYRIDINECARBOXYLATES

      Archiv der pharmazie
    69. CHERAGHALI AM; KUMAR R; KNAUS EE; WIEBE LI
      PHARMACOKINETICS AND BIOAVAILABILITY OF 5-ETHYL-2'-DEOXYURIDINE AND ITS NOVEL (5R,6R)-5-BROMO-6-ETHOXY-5,6-DIHYDRO PRODRUGS IN MICE

      Drug metabolism and disposition
    70. CHERAGHALI AM; MORIN KW; KUMAR R; KNAUS EE; WIEBE LI
      ACCUMULATION OF 5-ETHYL-2'-DEOXYURIDINE AND ITS 5,6-DIHYDRO PRODRUGS IN MURINE LUNG AND ITS POTENTIAL CLINICAL-APPLICATION

      Journal of Pharmacy and Pharmacology
    71. VO D; MATOWE WC; RAMESH M; IQBAL N; WOLOWYK MW; HOWLETT SE; KNAUS EE
      SYNTHESES, CALCIUM-CHANNEL AGONIST-ANTAGONIST MODULATION ACTIVITIES, AND VOLTAGE-CLAMP STUDIES OF ISOPROPYL DIMETHYL-3-NITRO-4-PYRIDINYLPYRIDINE-5-CARBOXYLATE RACEMATES AND ENANTIOMERS

      Journal of medicinal chemistry
    72. BALZARINI J; ANDREI G; KUMAR R; KNAUS EE; WIEBE LI; DECLERCQ E
      THE CYTOSTATIC ACTIVITY OF 5-(1-AZIDOVINYL)-2'-DEOXYURIDINE (AZVDU) AGAINST HERPES-SIMPLEX VIRUS THYMIDINE KINASE GENE-TRANSFECTED FM3A CELLS IS DUE TO INHIBITION OF THYMIDYLATE SYNTHASE AND ENHANCED BY UV-LIGHT (LAMBDA=254 NM) EXPOSURE

      FEBS letters
    73. WEI ZY; KNAUS EE
      ONE-STEP REDUCTION-WITTIG OLEFINATION OF METHYL PYROGLUTAMATE - CHIRAL SYNTHESES OF (5S)-5-ALKENYL-2-PYRROLIDINONES AND (S)-VIGABATRIN(R)

      Synlett
    74. IQBAL N; VO D; MCEWEN CA; WOLOWYK MW; KNAUS EE
      ENANTIOSELECTIVE SYNTHESES AND CALCIUM-CHANNEL MODULATING EFFECTS OF (-3-ISOPROPYL AND (-)-3-ISOPROPYL 5-(4-METHYLPHENETHYL) METHYL-4-(2-PYRIDYL)-3,5-PYRIDINEDICARBOXYLATES())

      Chirality
    75. CHERAGHALI AM; KNAUS EE; WIEBE LI
      BIOAVAILABILITY AND PHARMACOKINETIC PARAMETERS FOR 5-ETHYL-2'-DEOXYURIDINE

      Antiviral research
    76. KUMAR R; KNAUS EE; WIEBE LF; ALLEN TM
      SYNTHESIS OF 5-[1-HYDROXY (OR METHOXY)-2,2-DIHALOETHYL]-2'-DEOXYURIDINES WITH ANTIVIRAL AND CYTOTOXIC ACTIVITY

      Antiviral research
    77. WEI ZY; KNAUS EE
      A MECHANISM-BASED CLEAVAGE OF LACTAM-CARBAMATES

      Tetrahedron letters
    78. WEI ZY; KNAUS EE
      A REGIOSELECTIVE TANDEM REDUCTION - WITTIG-HORNER REACTION INVOLVING THE ALPHA-ESTER MOIETY OF DIETHYL ASPARTATE OR GLUTAMATE

      Tetrahedron letters
    79. WEI ZY; KNAUS EE
      ASYMMETRIC-SYNTHESIS OF BOTH ENANTIOMERS OF VIGABATRIN(R) - AN APPROACH USING METHIONINE AS THE CHIRAL POOL

      Tetrahedron
    80. WEI ZY; KNAUS EE
      IMPROVED SYNTHESIS OF CHIRAL N-PROTECTED ALLYLIC AMINES

      Synthesis
    81. WEI ZY; KNAUS EE
      RESOLUTION OF 5-VINYL-2-PYRROLIDINONE - A PRACTICAL SYNTHESIS OF (S)-VIGABATRIN AND (R)-VIGABATRIN

      Organic preparations and procedures international
    82. WEI ZY; KNAUS EE
      AN EFFICIENT ONE-POT CONVERSION OF ALPHA-AMINO-ACID ESTERS TO GAMMA-AMINO-ALPHA,BETA-UNSATURATED CARBOXYLATES

      Organic preparations and procedures international
    83. KUMAR R; WANG LL; WIEBE LI; KNAUS EE
      SYNTHESIS, IN-VITRO BIOLOGICAL STABILITY, AND ANTI-HIV ACTIVITY OF 6-HALO-6-ALKOXY(OR AZIDO)-5,6-DIHYDRO-3'-AZIDO-3'-DEOXYTHYMIDINE DIASTEREOMERS AS POTENTIAL PRODRUGS TO 3'-AZIDO-3'-DEOXYTHYMIDINE (AZT)

      Journal of medicinal chemistry
    84. KUMAR R; WANG L; WIEBE LI; KNAUS EE
      SYNTHESIS AND ANTIVIRAL (HIV-1, HBV) ACTIVITIES OF (OR-AZIDO)-5,6-DIHYDRO-3'-FLUORO-3'-DEOXYTHYMIDINE DIASTEREOMERS - POTENTIAL PRODRUGS TO3'-FLUORO-3'-DEOXYTHYMIDINE

      Journal of medicinal chemistry
    85. KUMAR R; WIEBE LI; KNAUS EE
      A MILD AND EFFICIENT METHODOLOGY FOR THE SYNTHESIS OF 5-HALOGENO URACIL NUCLEOSIDES THAT OCCURS VIA A 5-HALOGENO-6-AZIDO-5,6-DIHYDRO INTERMEDIATE

      Canadian journal of chemistry
    86. ELLORY JC; CULLIFORD SJ; SMITH PA; WOLOWYK MW; KNAUS EE
      SPECIFIC-INHIBITION OF CA-ACTIVATED K-CHANNELS IN RED-CELLS BY SELECTED DIHYDROPYRIDINE DERIVATIVES

      British Journal of Pharmacology
    87. CHERAGHALI AM; KUMAR R; WANG L; KNAUS EE; WIEBE LI
      SYNTHESIS, BIOTRANSFORMATION, PHARMACOKINETICS, AND ANTIVIRAL PROPERTIES OF ETHYL-5-HALO-6-METHOXY-5,6-DIHYDRO-2'-DEOXYURIDINE DIASTEREOMERS

      Biochemical pharmacology
    88. WEI ZY; KNAUS EE
      ASYMMETRIC-SYNTHESIS OF (S)-VIGABATRIN - AN APPROACH USING METHIONINEAS THE CHIRAL POOL

      Synlett
    89. KUMAR R; KNAUS EE; WIEBE LI
      SYNTHESIS OF HYDROPYRIDYL-3-CARBONYL)-2'-FLUORO-2'-DEOXYURIDINE (IVFRU-CDS) FOR BRAIN TARGETED DELIVERY OF IVFRU, AN ANTIVIRAL NUCLEOSIDE

      Nucleosides & nucleotides
    90. KUMAR R; WIEBE LI; KNAUS EE
      SYNTHESIS AND ANTIVIRAL ACTIVITY OF 1-BETA-D-ARABINOFURANOSYLURACILS AND URIDINES CONTAINING 5-[2-BROMO-2-CHLORO (OR BROMO)-1-HYDROXY (OR METHOXY) ETHYL] SUBSTITUENTS

      Nucleosides & nucleotides
    91. KNAUS EE; KUMAR P
      SYNTHESIS AND ANTIINFLAMMATORY ACTIVITY OF 5-(1,2-DIHYDROPYRIDYL)-TETRAZOL-2-ACETIC ACIDS, ESTERS AND AMIDES

      European journal of medicinal chemistry
    92. WEI ZY; KNAUS EE
      SYNTHESIS OF CHIRAL 5-SUBSTITUTED 2-PYRROLIDINONES - AN UNUSUAL ONE-STEP TRANSFORMATION

      Tetrahedron letters
    93. WEI ZY; KNAUS EE
      A PRACTICAL PROCEDURE FOR THE SYNTHESIS OF 5-SUBSTITUTED GAMMA-LACTAMS

      Organic preparations and procedures international
    94. KUMAR R; WIEBE LI; KNAUS EE
      SYNTHESIS AND ANTIVIRAL ACTIVITY OF NOVEL 5-(1-AZIDO-2-HALOETHYL) AND5-(1-AZIDOETHYL, AMINOETHYL, OR METHOXYETHYL) ANALOGS OF 2'-DEOXYURIDINE

      Journal of medicinal chemistry
    95. FIAKPUI CY; ARORA VK; KNAUS EE
      SYNTHESIS OF METHYLCARBONYLAMINO-4-BENZOYL-1,2-DIHYDROPYRIDINES AND THEIR CYCLIZATION TO ,9-TETRAHYDRO-2H-PYRIDO[3,4-E]-1,4-DIAZEPIN-2-ONES

      Journal of heterocyclic chemistry
    96. MORIN KW; WIEBE LI; KNAUS EE
      SYNTHESIS OF BRAIN-TARGETED RO-BETA-D-RIBOFURANOSYL)-(E)-5-(2-IODOVINYL)URACIL COUPLED TO A DIHYDROPYRIDINE REVERSIBLE-ARROW PYRIDINIUM SALT REDOX CHEMICAL-DELIVERY SYSTEM

      Carbohydrate research


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/02/20 alle ore 00:38:04