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    1. Adjei, AA; Davis, JN; Bruzek, LM; Erlichman, C; Kaufmann, SH
      Synergy of the protein farnesyltransferase inhibitor SCH66336 and cisplatin in human cancer cell lines

      CLINICAL CANCER RESEARCH
    2. Mow, BMF; Blajeski, AL; Chandra, J; Kaufmann, SH
      Apoptosis and the response to anticancer therapy

      CURRENT OPINION IN ONCOLOGY
    3. Karp, JE; Kaufmann, SH; Adjei, AA; Lancet, JE; Wright, JJ; End, DW
      Current status of clinical trials of farnesyltransferase inhibitors

      CURRENT OPINION IN ONCOLOGY
    4. Kaufmann, SH; Hengartner, MO
      Programmed cell death: alive and well in the new millennium

      TRENDS IN CELL BIOLOGY
    5. Alberts, SR; Erlichman, C; Sloan, J; Okuno, SH; Burch, PA; Rubin, J; Pitot, HC; Goldberg, RM; Adjei, AA; Atherton, PJ; Kaufmann, SH
      Phase I trial of gemcitabine and CPT-11 given weekly for four weeks every six weeks

      ANNALS OF ONCOLOGY
    6. Gores, GJ; Kaufmann, SH
      Is TRAIL hepatotoxic?

      HEPATOLOGY
    7. Cowan, CM; Thai, J; Krajewski, S; Reed, JC; Nicholson, DW; Kaufmann, SH; Roskams, AJ
      Caspases 3 and 9 send a pro-apoptotic signal from synapse to cell body in olfactory receptor neurons

      JOURNAL OF NEUROSCIENCE
    8. Blajeski, AL; Kottke, TJ; Kaufmann, SH
      A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines

      EXPERIMENTAL CELL RESEARCH
    9. Adams, RR; Eckley, DM; Vagnarelli, P; Wheatley, SP; Gerloff, DL; Mackay, AM; Svingen, PA; Kaufmann, SH; Earnshaw, WC
      Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes andis overexpressed in tumour cells

      CHROMOSOMA
    10. Erlichman, C; Boerner, SA; Hallgren, CG; Spieker, R; Wang, XY; James, CD; Scheffer, GL; Maliepaard, M; Ross, DD; Bible, KC; Kaufmann, SH
      The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistanceprotein-mediated drug efflux

      CANCER RESEARCH
    11. Shridhar, V; Bible, KC; Staub, J; Avula, R; Lee, YK; Kalli, K; Huang, HJ; Hartmann, LC; Kaufmann, SH; Smith, DI
      Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer

      CANCER RESEARCH
    12. Boerner, SA; Tourne, ME; Kaufmann, SH; Bible, KC
      Effect of P-glycoprotein on flavopiridol sensitivity

      BRITISH JOURNAL OF CANCER
    13. Senchenkov, A; Han, TY; Wang, HT; Frankel, AE; Kottke, TJ; Kaufmann, SH; Cabot, MC
      Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT388-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF

      BLOOD
    14. Karp, JE; Lancet, JE; Kaufmann, SH; End, DW; Wright, JJ; Bol, K; Horak, I; Tidwell, ML; Liesveld, J; Kottke, TJ; Ange, D; Buddharaju, L; Gojo, I; Highsmith, WE; Belly, RT; Hohl, RJ; Rybak, ME; Thibault, A; Rosenblatt, J
      Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial

      BLOOD
    15. Kaufmann, SH
      Reutilization of immunoblots after chemiluminescent detection

      ANALYTICAL BIOCHEMISTRY
    16. Adjei, AA; Davis, JN; Erlichman, C; Svingen, PA; Kaufmann, SH
      Comparison of potential markers of farnesyltransferase inhibition

      CLINICAL CANCER RESEARCH
    17. Bible, KC; Boerner, SA; Kirkland, K; Anderl, KL; Bartelt, D; Svingen, PA; Kottke, TJ; Lee, YK; Eckdahl, S; Stalboerger, PG; Jenkins, RB; Kaufmann, SH
      Characterization of an ovarian carcinoma cell line resistant to cisplatin and flavopiridol

      CLINICAL CANCER RESEARCH
    18. Witzig, TE; Timm, M; Stenson, M; Svingen, PA; Kaufmann, SH
      Induction of apoptosis in malignant B cells by phenylbutyrate or phenylacetate in combination with chemotherapeutic agents

      CLINICAL CANCER RESEARCH
    19. Svingen, PA; Tefferi, A; Kottke, TJ; Kaur, G; Narayanan, VL; Sausville, EA; Kaufmann, SH
      Effect of the bcr/abl kinase inhibitors AG957 and NSC 680410 on chronic myelogenous leukemia cells in vitro

      CLINICAL CANCER RESEARCH
    20. Kaufmann, SH; Gores, GJ
      Apoptosis in cancer: cause and cure

      BIOESSAYS
    21. Kaufmann, SH; Mesner, PW; Samejima, K; Tone, S; Earnshaw, WC
      Detection of DNA cleavage in apoptotic cells

      APOPTOSIS
    22. Budihardjo, II; Boerner, SA; Eckdahl, S; Svingen, PA; Rios, R; Ames, MM; Kaufmann, SH
      Effect of 6-aminonicotinamide and other protein synthesis inhibitors on formation of platinum-DNA adducts and cisplatin sensitivity

      MOLECULAR PHARMACOLOGY
    23. Perola, E; Xu, K; Kollmeyer, TM; Kaufmann, SH; Prendergast, FG; Pang, YP
      Successful virtual screening of a chemical database for farnesyltransferase inhibitor leads

      JOURNAL OF MEDICINAL CHEMISTRY
    24. Guicciardi, ME; Deussing, J; Miyoshi, H; Bronk, SF; Svingen, PA; Peters, C; Kaufmann, SH; Gores, GJ
      Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

      JOURNAL OF CLINICAL INVESTIGATION
    25. Thangaraju, M; Kaufmann, SH; Couch, FJ
      BRCA1 facilitates stress-induced apoptosis in breast and ovarian cancer cell lines

      JOURNAL OF BIOLOGICAL CHEMISTRY
    26. Burtelow, MA; Kaufmann, SH; Karnitz, LM
      Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage

      JOURNAL OF BIOLOGICAL CHEMISTRY
    27. Kaufmann, SH; Earnshaw, WC
      Induction of apoptosis by cancer chemotherapy

      EXPERIMENTAL CELL RESEARCH
    28. Bible, KC; Bible, RH; Kottke, TJ; Svingen, PA; Xu, K; Pang, YP; Hajdu, E; Kaufmann, SH
      Flavopiridol binds to duplex DNA

      CANCER RESEARCH
    29. Adjei, AA; Erlichman, C; Davis, JN; Cutler, DL; Sloan, JA; Marks, RS; Hanson, LJ; Svingen, PA; Atherton, P; Bishop, WR; Kirschmeier, P; Kaufmann, SH
      A Phase I trial of the farnesyl transferase inhibitor SCH66336: Evidence for biological and clinical activity

      CANCER RESEARCH
    30. Svingen, PA; Karp, JE; Krajewski, S; Mesner, PW; Gore, SD; Burke, PJ; Reed, JC; Lazebnik, YA; Kaufmann, SH
      Evaluation of Apaf-1 and procaspases-2,-3,-7,-8, and-9 as potential prognostic markers in acute leukemia

      BLOOD
    31. Earnshaw, WC; Martins, LM; Kaufmann, SH
      Mammalian caspases: Structure, activation, substrates, and functions during apoptosis

      ANNUAL REVIEW OF BIOCHEMISTRY
    32. Kumar, S; Mow, BMF; Kaufmann, SH
      Hypercalcemia complicating leukemic transformation of agnogenic myeloid metaplasia-myelofibrosis

      MAYO CLINIC PROCEEDINGS
    33. Faubion, WA; Guicciardi, ME; Miyoshi, H; Bronk, SF; Roberts, PJ; Svingen, PA; Kaufmann, SH; Gores, GJ
      Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas

      JOURNAL OF CLINICAL INVESTIGATION
    34. Samejima, K; Svingen, PA; Basi, GS; Kottke, T; Mesner, PW; Stewart, L; Durrieu, F; Poirier, GG; Alnemri, ES; Champoux, JJ; Kaufmann, SH; Earnshaw, WC
      Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis

      JOURNAL OF BIOLOGICAL CHEMISTRY
    35. Mesner, PW; Bible, KC; Martins, LM; Kottke, TJ; Srinivasula, SM; Svingen, PA; Chilcote, TJ; Basi, GS; Tung, JS; Krajewski, S; Reed, JC; Alnemri, ES; Earnshaw, WC; Kaufmann, SH
      Characterization of caspase processing and activation in HL-60 cell cytosol under cell-free conditions - Nucleotide requirement and inhibitor profile

      JOURNAL OF BIOLOGICAL CHEMISTRY
    36. Kottke, TJ; Blajeski, AL; Martins, LM; Mesner, PW; Davidson, NE; Earnshaw, WC; Armstrong, DK; Kaufmann, SH
      Comparison of paclitaxel-, 5-fluoro-2 '-deoxyuridine-, and epidermal growth factor (EGF)-induced apoptosis - Evidence for EGF-induced anoikis

      JOURNAL OF BIOLOGICAL CHEMISTRY
    37. Yamashita, K; Takahashi, A; Kobayashi, S; Hirata, H; Mesner, PW; Kaufmann, SH; Yonehara, S; Yamamoto, K; Uchiyama, T; Sasada, M
      Caspases mediate tumor necrosis factor-alpha-induced neutrophil apoptosis and downregulation of reactive oxygen production

      BLOOD
    38. Walker, DL; Reid, JM; Svingen, PA; Rios, R; Covey, JM; Alley, MC; Hollingshead, MG; Budihardjo, II; Eckdahl, S; Boerner, SA; Kaufmann, SH; Ames, MM
      Murine pharmacokinetics of 6-aminonicotinamide (NSC 21206), a novel biochemical modulating agent

      BIOCHEMICAL PHARMACOLOGY
    39. Bible, KC; Boerner, SA; Kaufmann, SH
      A one-step method for protein estimation in biological samples: Nitration of tyrosine in nitric acid

      ANALYTICAL BIOCHEMISTRY
    40. Kaufmann, SH; Svingen, PA
      Immunoblot analysis and band depletion assays

      DNA TOPOISOMERASE PROTOCOLS, VOLUME 1: DNA TOPOLOGY AND ENZYMES
    41. ADJEI AA; CHARRON M; ROWINSKY EK; SVINGEN PA; MILLER J; REID JM; SEBOLTLEOPOLD J; AMES MM; KAUFMANN SH
      EFFECT OF PYRAZOLOACRIDINE (NSC-366140) ON DNA TOPOISOMERASE-I AND TOPOISOMERASE-II

      Clinical cancer research
    42. ADJEI AA; CHARRON M; ROWINSKY EK; SVINGEN PA; MILLER J; REID JM; SEBOLTLEOPOLD J; AMES MM; KAUFMANN SH
      EFFECT OF PYRAZOLOACRIDINE (NSC-366140) ON DNA TOPOISOMERASE-I AND TOPOISOMERASE-II

      Clinical cancer research
    43. GORE SD; ROWINSKY EK; MILLER CB; GRIFFIN C; CHEN TL; BOROWITZ M; DONEHOWER RC; BURKS KL; ARMSTRONG DK; BURKE PJ; GREVER MR; KAUFMANN SH
      A PHASE-II WINDOW STUDY OF TOPOTECAN IN UNTREATED PATIENTS WITH HIGH-RISK ADULT ACUTE LYMPHOBLASTIC-LEUKEMIA

      Clinical cancer research
    44. BUDIHARDJO II; WALKER DL; SVINGEN PA; BUCKWALTER CA; DESNOYERS S; ECKDAHL S; SHAH GM; POIRIER GG; REID JM; AMES MM; KAUFMANN SH
      6-AMINONICOTINAMIDE SENSITIZES HUMAN TUMOR-CELL LINES TO CISPLATIN

      Clinical cancer research
    45. BUDIHARDJO II; WALKER DL; SVINGEN PA; BUCKWALTER CA; DESNOYERS S; ECKDAHL S; SHAH GM; POIRIER GG; REID JM; AMES MM; KAUFMANN SH
      6-AMINONICOTINAMIDE SENSITIZES HUMAN TUMOR-CELL LINES TO CISPLATIN

      Clinical cancer research
    46. KAUFMANN SH; GORE SD; MILLER CB; JONES RJ; ZWELLING LA; SCHNEIDER E; BURKE PJ; KARP JE
      TOPOISOMERASE-II AND THE RESPONSE TO ANTILEUKEMIC THERAPY

      Leukemia & lymphoma
    47. ERLICHMAN C; BOERNER S; KAUFMANN SH
      INTERACTIONS OF OXALIPLATIN WITH THE TOPOISOMERASE-I INHIBITORS TOPOTECAN AND SN-38

      Annals of oncology
    48. MULLANY S; SVINGEN PA; KAUFMANN SH; ERLICHMAN C
      EFFECT OF ADDING THE TOPOISOMERASE-I POISON 7-ETHYL-10-HYDROXYCAMPTOTHECIN (SN-38) TO 5-FLUOROURACIL AND FOLINIC ACID IN HCT-8 CELLS - ELEVATED DTTP POOLS AND ENHANCED CYTOTOXICITY

      Cancer chemotherapy and pharmacology
    49. BUDIHARDJO II; POIRIER GG; KAUFMANN SH
      APPARENT CLEAVAGE OF POLY(ADP-RIBOSE) POLYMERASE IN NON-APOPTOTIC MOUSE LTA CELLS - AN ARTIFACT OF CROSS-REACTIVE SECONDARY ANTIBODY

      Molecular and cellular biochemistry
    50. KAUFMANN SH
      CELL-DEATH INDUCED BY TOPOISOMERASE-TARGETED DRUGS - MORE QUESTIONS THAN ANSWERS

      Biochimica et biophysica acta, N. Gene structure and expression
    51. ADJEI AA; KAUFMANN SH; ALBERTS SR; GOLDBERG RM; REID J; SLOAN JA; ERLICHMAN C
      THE SEARCH FOR CYTOTOXIC SYNERGY - AN IN-VITRO AND CLINICAL-STUDY OF PYRAZOLOACRIDINE (PZA) AND CARBOPLATIN (CBDCA) IN SOLID TUMORS

      Naunyn-Schmiedeberg's archives of pharmacology
    52. SAMEJIMA K; TONE S; KOTTKE TJ; ENARI M; SAKAHIRA H; COOKE CA; DURRIEU F; MARTINS LM; NAGATA S; KAUFMANN SH; EARNSHAW WC
      TRANSITION FROM CASPASE-DEPENDENT TO CASPASE-INDEPENDENT MECHANISMS AT THE ONSET OF APOPTOTIC EXECUTION

      The Journal of cell biology
    53. KARNES WE; WELLER SG; ADJEI PN; KOTTKE TJ; GLENN KS; GORES GJ; KAUFMANN SH
      INHIBITION OF EPIDERMAL GROWTH-FACTOR RECEPTOR KINASE INDUCES PROTEASE-DEPENDENT APOPTOSIS IN HUMAN COLON-CANCER CELLS

      Gastroenterology
    54. MARTINS LM; KOTTKE TJ; KAUFMANN SH; EARNSHAW WC
      PHOSPHORYLATED FORMS OF ACTIVATED CASPASES ARE PRESENT IN CYTOSOL FROM HL-60 CELLS DURING ETOPOSIDE-INDUCED APOPTOSIS

      Blood
    55. KAUFMANN SH; KARP JE; SVINGEN PA; KRAJEWSKI S; BURKE PJ; GORE SD; REED JC
      ELEVATED EXPRESSION OF THE APOPTOTIC REGULATOR MCL-1 AT THE TIME OF LEUKEMIC RELAPSE

      Blood
    56. ADJEI AA; BUDIHARDJO II; ROWINSKY EK; KOTTKE TJ; SVINGEN PA; BUCKWALTER CA; GROCHOW LB; DONEHOWER RC; KAUFMANN SH
      CYTOTOXIC SYNERGY BETWEEN PYRAZOLOACRIDINE (NSC-366140) AND CISPLATININ-VITRO - INHIBITION OF PLATINUM-DNA ADDUCT REMOVAL

      Clinical cancer research
    57. KAUFMANN SH; KARP JE; BURKE PJ; GORE SD
      ADDITION OF ETOPOSIDE TO INITIAL THERAPY OF ADULT ACUTE LYMPHOBLASTIC-LEUKEMIA - A COMBINED CLINICAL AND LABORATORY STUDY (VOL 23, PG 71, PG 1996)

      Leukemia & lymphoma
    58. VILLA P; KAUFMANN SH; EARNSHAW WC
      CASPASES AND CASPASE INHIBITORS

      Trends in biochemical sciences
    59. KAUFMANN SH
      RESISTANCE TO TOPOISOMERASE-II POISONS - IS THE ANSWER IN THE PROMOTER

      Leukemia research
    60. ROWINSKY EK; KAUFMANN SH
      TOPOTECAN IN COMBINATION CHEMOTHERAPY

      Seminars in oncology
    61. ADJEI PN; KAUFMANN SH; LEUNG WY; MAO F; GORES GJ
      SELECTIVE INDUCTION OF APOPTOSIS IN HEP 3B CELLS BY TOPOISOMERASE-I INHIBITORS - EVIDENCE FOR A PROTEASE-DEPENDENT PATHWAY THAT DOES NOT ACTIVATE CYSTEINE PROTEASE-32 (VOL 98, PG 2588, 1996)

      The Journal of clinical investigation
    62. MARTINS LM; KOTTKE T; MESNER PW; BASI GS; SINHA S; FRIGON N; TATAR E; TUNG JS; BRYANT K; TAKAHASHI A; SVINGEN PA; MADDEN BJ; MCCORMICK DJ; EARNSHAW WC; KAUFMANN SH
      ACTIVATION OF MULTIPLE INTERLEUKIN-1-BETA CONVERTING-ENZYME HOMOLOGS IN CYTOSOL AND NUCLEI OF HL-60 CELLS DURING ETOPOSIDE-INDUCED APOPTOSIS

      The Journal of biological chemistry
    63. KELLNER U; HUTCHINSON L; SEIDEL A; LAGE H; DANKS MK; DIETEL M; KAUFMANN SH
      DECREASED DRUG ACCUMULATION IN A MITOXANTRONE-RESISTANT GASTRIC-CARCINOMA CELL-LINE IN THE ABSENCE OF P-GLYCOPROTEIN

      International journal of cancer
    64. ADJEI PN; KAUFMANN SH; GORES GJ
      A UNIQUE CATHEPSIN PROTEASE CASCADE CONTRIBUTES TO APOPTOSIS OF HEP 3B CELLS BY CAMPTOTHECIN

      Gastroenterology
    65. ISSA JPJ; ZEHNBAUER BA; KAUFMANN SH; BIEL MA; BAYLIN SB
      HIC1 HYPERMETHYLATION IS A LATE EVENT IN HEMATOPOIETIC NEOPLASMS

      Cancer research
    66. BIBLE KC; KAUFMANN SH
      CYTOTOXIC SYNERGY BETWEEN FLAVOPIRIDOL (NSC-649890, L86-8275) AND VARIOUS ANTINEOPLASTIC AGENTS - THE IMPORTANCE OF SEQUENCE OF ADMINISTRATION

      Cancer research
    67. EISCHEN CM; KOTTKE TJ; MARTINS LM; BASI GS; TUNG JS; EARNSHAW WC; LEIBSON PJ; KAUFMANN SH
      COMPARISON OF APOPTOSIS IN WILD-TYPE AND FAS-RESISTANT CELLS - CHEMOTHERAPY-INDUCED APOPTOSIS IS NOT DEPENDENT ON FAS FAS LIGAND INTERACTIONS/

      Blood
    68. MARTINS LM; MESNER PW; KOTTKE TJ; BASI GS; SINHA S; TUNG JS; SVINGEN PA; MADDEN BJ; TAKAHASHI A; MCCORMICK DJ; EARNSHAW WC; KAUFMANN SH
      COMPARISON OF CASPASE ACTIVATION AND SUBCELLULAR-LOCALIZATION IN HL-60 AND K562 CELLS UNDERGOING ETOPOSIDE-INDUCED APOPTOSIS

      Blood
    69. SOTOMAYOR EM; PIANTADOSI S; MILLER CB; KARP JE; KAUFMANN SH; BRAINE H; HUMPHREY RL; BURKE PJ; GORE SD
      LONG-TERM FOLLOW-UP OF INTENSIVE, ARA-C-BASED CHEMOTHERAPY FOLLOWED BY BONE-MARROW TRANSPLANTATION (BMT) FOR ADULT ACUTE LYMPHOCYTIC-LEUKEMIA (ALL) - IMPROVED SURVIVAL WITH ALLOGENEIC, BUT NOT AUTOLOGOUS BMT

      Blood
    70. KAUFMANN SH; SVINGEN PA; GORE SD; ARMSTRONG DK; CHENG YC; ROWINSKY EK
      ALTERED FORMATION OF TOPOTECAN-STABILIZED TOPOISOMERASE-I DNA-ADDUCTSIN HUMAN LEUKEMIA-CELLS

      Blood
    71. KAUFMANN SH
      PROTEOLYTIC CLEAVAGE DURING CHEMOTHERAPY-INDUCED APOPTOSIS

      Molecular medicine today
    72. MCCLOSKEY DE; KAUFMANN SH; PRESTIGIACOMO LJ; DAVIDSON NE
      PACLITAXEL INDUCES PROGRAMMED CELL-DEATH IN MDA-MB-468 HUMAN BREAST-CANCER CELLS

      Clinical cancer research
    73. ROWINSKY EK; KAUFMANN SH; BAKER SD; MILLER CB; SARTORIUS SE; BOWLING MK; CHEN TL; DONEHOWER RC; GORE SD
      A PHASE-I AND PHARMACOLOGICAL STUDY OF TOPOTECAN INFUSED OVER 30 MINUTES FOR 5 DAYS IN PATIENTS WITH REFRACTORY ACUTE-LEUKEMIA

      Clinical cancer research
    74. KAUFMANN SH; KARP JE; BURKE PJ; GORE SD
      ADDITION OF ETOPOSIDE TO INITIAL THERAPY OF ADULT ACUTE LYMPHOBLASTIC-LEUKEMIA - A COMBINED CLINICAL AND LABORATORY STUDY

      Leukemia & lymphoma
    75. PATEL T; GORES GJ; KAUFMANN SH
      THE ROLE OF PROTEASES DURING APOPTOSIS

      The FASEB journal
    76. ROWINSKY EK; GROCHOW LB; SARTORIUS SE; BOWLING MK; KAUFMANN SH; PEEREBOOM D; DONEHOWER RC
      PHASE-I AND PHARMACOLOGICAL STUDY OF HIGH-DOSES OF THE TOPOISOMERASE-I INHIBITOR TOPOTECAN WITH GRANULOCYTE-COLONY-STIMULATING FACTOR IN PATIENTS WITH SOLID TUMORS

      Journal of clinical oncology
    77. ROWINSKY EK; KAUFMANN SH; BAKER SD; GROCHOW LB; CHEN TL; PEEREBOOM D; BOWLING MK; SARTORIUS SE; ETTINGER DS; FORASTIERE AA; DONEHOWER RC
      SEQUENCES OF TOPOTECAN AND CISPLATIN - PHASE-I, PHARMACOLOGICAL, AND IN-VITRO STUDIES TO EXAMINE SEQUENCE DEPENDENCE

      Journal of clinical oncology
    78. ADJEI PN; KAUFMANN SH; GORES GJ
      CATHEPSIN-B PROTEASE ACTIVITY BUT NOT INTERLEUKIN-1 BETA-CONVERTING ENZYME (ICE) PROTEASES CONTRIBUTES TO CAMPTOTHECIN-INDUCED APOPTOSIS INA HUMAN HEPATOCELLULAR-CARCINOMA CELL-LINE

      Hepatology
    79. RAMIREZ JJ; KAUFMANN SH; WINDEBANK AJ
      PACLITAXEL POTENTIATES CISPLATIN NEUROTOXICITY IN DORSAL-ROOT GANGLION NEURONS

      Neurology
    80. TAKAHASHI A; ALNEMRI ES; LAZEBNIK YA; FERNANDESALNEMRI T; LITWACK G; MOIR RD; GOLDMAN RD; POIRIER GG; KAUFMANN SH; EARNSHAW WC
      CLEAVAGE OF LAMIN-A BY MCH2-ALPHA BUT NOT CPP32 - MULTIPLE INTERLEUKIN 1-BETA-CONVERTING ENZYME-RELATED PROTEASES WITH DISTINCT SUBSTRATE RECOGNITION PROPERTIES ARE ACTIVE IN APOPTOSIS

      Proceedings of the National Academy of Sciences of the United Statesof America
    81. UBOL S; SUK P; BUDIHARDJO I; DESNOYERS S; MONTROSE MH; POIRIER GG; KAUFMANN SH; GRIFFIN DE
      TEMPORAL CHANGES IN CHROMATIN, INTRACELLULAR CALCIUM, AND POLY(ADP-RIBOSE) POLYMERASE DURING SINDBIS VIRUS-INDUCED APOPTOSIS OF NEUROBLASTOMA-CELLS

      Journal of virology
    82. ADJEI PN; KAUFMANN SH; LEUNG WY; MAO F; GORES GJ
      SELECTIVE INDUCTION OF APOPTOSIS IN HEP 3B CELLS BY TOPOISOMERASE-I INHIBITORS - EVIDENCE FOR A PROTEASE-DEPENDENT PATHWAY THAT DOES NOT ACTIVATE CYSTEINE PROTEASE P-32

      The Journal of clinical investigation
    83. MANDAL M; MAGGIRWAR SB; SHARMA N; KAUFMANN SH; SUN SC; KUMAR R
      BCL-2 PREVENTS CD95 (FAS APO-1)-INDUCED DEGRADATION OF LAMIN-B AND POLY(ADP-RIBOSE) POLYMERASE AND RESTORES THE NF-KAPPA-B SIGNALING PATHWAY/

      The Journal of biological chemistry
    84. HANANO R; REIFENBERG K; KAUFMANN SH
      NATURALLY ACQUIRED PNEUMOCYSTIS-CARINII PNEUMONIA IN GENE DISRUPTION MUTANT MICE - ROLES OF DISTINCT T-CELL POPULATIONS IN INFECTION

      Infection and immunity
    85. ADJEI PN; KAUFMANN SH; GORES GJ
      SELECTIVE INDUCTION OF APOPTOSIS IN A HUMAN HEPATOCELLULAR-CARCINOMA (HCC) CELL-LINE BY THE TOPOISOMERASE-I INHIBITOR CAMPTOTHECIN

      Gastroenterology
    86. DESNOYERS S; KAUFMANN SH; POIRIER GG
      ALTERATION OF THE NUCLEOLAR LOCALIZATION OF POLY(ADP-RIBOSE) POLYMERASE UPON TREATMENT WITH TRANSCRIPTION INHIBITORS

      Experimental cell research
    87. BUCKWALTER CA; LIN AH; TANIZAWA A; POMMIER YG; CHENG YC; KAUFMANN SH
      RNA-SYNTHESIS INHIBITORS ALTER THE SUBNUCLEAR DISTRIBUTION OF DNA TOPOISOMERASE-I

      Cancer research
    88. ISSA JPJ; ZEHNBAUER BA; CIVIN CI; COLLECTOR MI; SHARKIS SJ; DAVIDSON NE; KAUFMANN SH; BAYLIN SB
      THE ESTROGEN-RECEPTOR CPG ISLAND IS METHYLATED IN MOST HEMATOPOIETIC NEOPLASMS

      Cancer research
    89. BIBLE KC; KAUFMANN SH
      FLAVOPIRIDOL - A CYTOTOXIC FLAVONE THAT INDUCES CELL-DEATH IN NONCYCLING A549 HUMAN LUNG-CARCINOMA CELLS

      Cancer research
    90. CAROW CE; LEVENSTEIN M; KAUFMANN SH; CHEN J; AMIN S; ROCKWELL P; WITTE L; BOROWITZ MJ; CIVIN CI; SMALL D
      EXPRESSION OF THE HEMATOPOIETIC GROWTH-FACTOR RECEPTOR FLT3 (STK-1 FLK2) IN HUMAN LEUKEMIAS/

      Blood
    91. KAUFMANN SH; PEEREBOOM D; BUCKWALTER CA; SVINGEN PA; GROCHOW LB; DONEHOWER RC; ROWINSKY EK
      CYTOTOXIC EFFECTS OF TOPOTECAN COMBINED WITH VARIOUS ANTICANCER AGENTS IN HUMAN CANCER CELL-LINES

      Journal of the National Cancer Institute
    92. LAZEBNIK YA; TAKAHASHI A; POIRIER GG; KAUFMANN SH; EARNSHAW WC
      SPECIFIC PROTEOLYTIC ACTIVITIES AS THE DRIVING-FORCE OF APOPTOTIC DEATH

      AIDS research and human retroviruses
    93. ROWINSKY EK; NOE DA; GROCHOW LB; SARTORIOUS SE; BOWLING MK; CHEN TL; LUBEJKO BG; KAUFMANN SH; DONEHOWER RC
      PHASE-I AND PHARMACOLOGICAL STUDIES OF PYRAZOLOACRIDINE, A NOVEL DNA INTERCALATING AGENT, ON SINGLE-DOSING AND MULTIPLE-DOSING SCHEDULES

      Journal of clinical oncology
    94. ADJEI PN; KAUFMANN SH; GORES GJ
      TOPOISOMERASE-I INHIBITORS INDUCE APOPTOSIS IN A HUMAN HEPATOCELLULAR-CARCINOMA (HCC) CELL-LINE BY A PROTEASE SENSITIVE PATHWAY

      Hepatology
    95. SHA EC; SHA MC; KAUFMANN SH
      EVALUATION OF [1-(1-OXOTRIDECYL)-2-PIPERIDINYL]METHYL)HEXANAMIDE (NPC-15437), A PROTEIN-KINASE-C INHIBITOR, AS A MODULATOR OF P-GLYCOPROTEIN-MEDIATED RESISTANCE IN-VITRO

      Investigational new drugs
    96. LAZEBNIK YA; TAKAHASHI A; MOIR RD; GOLDMAN RD; POIRIER GG; KAUFMANN SH; EARNSHAW WC
      STUDIES OF THE LAMIN PROTEINASE REVEAL MULTIPLE PARALLEL BIOCHEMICAL PATHWAYS DURING APOPTOTIC EXECUTION

      Proceedings of the National Academy of Sciences of the United Statesof America
    97. LAZEBNIK YA; TAKAHASHI A; POIRIER GG; KAUFMANN SH; EARNSHAW WC
      CHARACTERIZATION OF THE EXECUTION PHASE OF APOPTOSIS IN-VITRO USING EXTRACTS FROM CONDEMNED-PHASE CELLS

      Journal of Cell Science
    98. KAUFMANN SH; CHARRON M; BURKE PJ; KARP JE
      CHANGES IN TOPOISOMERASE-I LEVELS AND LOCALIZATION DURING MYELOID MATURATION IN-VITRO AND IN-VIVO

      Cancer research
    99. DOYLE LA; ROSS DD; SRIDHARA R; FOJO AT; KAUFMANN SH; LEE EJ; SCHIFFER CA
      EXPRESSION OF A 95-KDA MEMBRANE-PROTEIN IS ASSOCIATED WITH LOW DAUNORUBICIN ACCUMULATION IN LEUKEMIC BLAST CELLS

      British Journal of Cancer
    100. JONES RJ; BARBER JP; VALA MS; COLLECTOR MI; KAUFMANN SH; LUDEMAN SM; COLVIN QM; HILTON J
      ASSESSMENT OF ALDEHYDE DEHYDROGENASE IN VIABLE CELLS

      Blood


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/21 alle ore 15:13:07