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Mutations of the CHK2 gene are found in some osteosarcomas, but are rare in breast, lung, and ovarian tumors
GENES CHROMOSOMES & CANCER
Vitamin D-3 and its synthetic analogs inhibit the spontaneous in vitro immunoglobulin production by SLE-derived PBMC
CLINICAL IMMUNOLOGY
Methylation analysis of cell cycle control genes in adult T-cell leukemia/lymphoma
LEUKEMIA & LYMPHOMA
Analysis of the CHK2 gene in lymphoid malignancies
LEUKEMIA & LYMPHOMA
Mutations in the mitotic check point gene, MAD1L1, in human cancers
ONCOGENE
C/EBP epsilon -/- mice: increased rate of myeloid proliferation and apoptosis
LEUKEMIA
Baicalin is a major component of PC-SPES which inhibits the proliferation of human cancer cells via apoptosis and cell cycle arrest
PROSTATE
Comparative genomic hybridization in childhood acute lymphoblastic leukemia: correlation with interphase cytogenetics and loss of heterozygosity analysis
CANCER GENETICS AND CYTOGENETICS
Mutation analysis of the DNA-damage checkpoint gene CHK2 in myelodysplastic syndromes and acute myeloid leukemias
LEUKEMIA RESEARCH
DNase I hypersensitivity analysis of the human CCAAT enhancer binding protein epsilon (C/EBR epsilon) gene
LEUKEMIA RESEARCH
Frequent loss of heterozygosity in the region of D1S450 at 1p36.2 in myelodysplastic syndromes
LEUKEMIA RESEARCH
Metabolism of 1 alpha,25-dihydroxyvitamin D-3 in human promyelocytic leukemia (HL-60) cells: In vitro biological activities of the natural metabolites of 1 alpha,25-dihydroxyvitamin D-3 produced in HL-60 cells
STEROIDS
Highly active analogs of 1 alpha,25-dihydroxyvitamin D-3 that resist metabolism through C-24 oxidation and C-3 epimerization pathways
STEROIDS
Structural and functional studies of CCAAT/enhancer-binding protein epsilon
JOURNAL OF BIOLOGICAL CHEMISTRY
Breast cancer - Cyr61 is overexpressed, estrogen-inducible, and associatedwith more advanced disease
JOURNAL OF BIOLOGICAL CHEMISTRY
Tumor necrosis factor alpha polymorphism associated with increased susceptibility to development of adult T-cell leukemia/lymphoma in human T-lymphotropic virus type 1 carriers
CANCER RESEARCH
24-oxo metabolites of vitamin D-3 analogues: Disassociation of their prominent antileukemic effects from their lack of calcium modulation
CANCER RESEARCH
Cyclin E is the only cyclin-dependent kinase 2-associated cyclin that predicts metastasis and survival in early stage non-small cell lung cancer
CANCER RESEARCH
Mutational analysis of the peroxisome proliferator-activated receptor gamma gene in human malignancies
CANCER RESEARCH
Expression of transferrin receptor 2 in normal and neoplastic hematopoietic cells
BLOOD
Regulation of expression of murine transferrin receptor 2
BLOOD
Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray
BLOOD
Neutrophil-specific granule deficiency: homozygous recessive inheritance of a frameshift mutation in the gene encoding transcription factor CCAAT/enhancer binding protein-epsilon
BLOOD
Novel vitamin D-3 analog, 21-(3-methyl-3-hydroxy-butyl)-19-nor D-3, that modulates cell growth, differentiation, apoptosis, cell cycle, and inductionof PTEN in leukemic cells
BLOOD
Cyclin A1 directly interacts with B-myb and cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function
BLOOD
Comparative genomic hybridization analysis in adult T-cell leukemia/lymphoma: correlation with clinical course
BLOOD
Effect of a novel vitamin D-3 analog, EB1089, on G(1) cell cycle regulatory proteins in HL-60 cells
INTERNATIONAL JOURNAL OF ONCOLOGY
Molecular analysis of the human myeloperoxidase promoter region
INTERNATIONAL JOURNAL OF ONCOLOGY
The anti-proliferative effects of 1 alpha,25(OH)(2)D-3 on breast and prostate cancer cells are associated with induction of BRCA1 gene expression
ONCOGENE
Allelotype analysis of the myelodysplastic syndrome
LEUKEMIA
Decreased expression of p33ING1 mRNA in lymphoid malignancies. (vol 62, pg118, 1999)
AMERICAN JOURNAL OF HEMATOLOGY
Methylation of the cyclin A1 promoter correlates with gene silencing in somatic cell lines, while tissue-specific expression of cyclin A1 is methylation independent
MOLECULAR AND CELLULAR BIOLOGY
PC-SPES: A unique inhibitor of proliferation of prostate cancer cells in vitro and in vivo
PROSTATE
Co-infection of HHV-6 and HHV-8 is rare in primary effusion lymphoma
LEUKEMIA RESEARCH
Synthesis and biological activities of the two C(23) epimers of 1 alpha,23,25-trihydroxy-24-oxo-19-nor-vitamin D-3: novel analogs of 1 alpha,23(S),25-trihydroxy-24-oxo-vitamin D-3, a natural metabolite of 1 alpha,25-dihydroxyvitamin D-3
STEROIDS
Characterization of a novel analogue of 1 alpha,25(OH)(2)-vitamin D-3 withtwo side chains: Interaction with its nuclear receptor and cellular actions
JOURNAL OF MEDICINAL CHEMISTRY
Effects of long-term administration of vitamin D-3 analogs to mice
JOURNAL OF ENDOCRINOLOGY
Transferrin receptor 2-alpha supports cell growth both in iron-chelated cultured cells and in vivo
JOURNAL OF BIOLOGICAL CHEMISTRY
Cell cycle arrest induced by the vitamin D-3 analog EB1089 in NCI-H929 myeloma cells is associated with induction of the cyclin-dependent kinase inhibitor p27
EXPERIMENTAL CELL RESEARCH
Down-regulation of prostate-specific antigen expression by ligands for peroxisome proliferator-activated receptor gamma in human prostate cancer
CANCER RESEARCH
Allelic loss in the progression of myelodysplastic syndrome
CANCER RESEARCH
Induction of apoptosis by vitamin D-3 analogue EB1089 in NCI-H929 myeloma cells via activation of caspase 3 and p38 MAP kinase
BRITISH JOURNAL OF HAEMATOLOGY
Novel therapeutic approach: organic arsenical (melarsoprol) alone or with all-trans-retinoic acid markedly inhibit growth of human breast and prostate cancer cells in vitro and in vivo
BRITISH JOURNAL OF CANCER
The aberrant fusion proteins PML-RAR alpha and PLZF-RAR alpha contribute to the overexpression of cyclin Al in acute promyelocytic leukemia
BLOOD
Representational difference analysis using myeloid cells from C/EBP epsilon deletional mice
BLOOD
HIV-1 protease inhibitors decrease proliferation and induce differentiation of human myelocytic leukemia cells
BLOOD
Hematopoietic-specific expression of MEFV, the gene mutated in familial Mediterranean fever, and subcellular localization of its corresponding protein, pyrin
BLOOD
Mutations of the E2F4 gene in hematological malignancies having microsatellite instability
BLOOD
A ligand of peroxisome proliferator-activated receptor gamma, retinoids, and prevention of preneoplastic mammary lesions
JOURNAL OF THE NATIONAL CANCER INSTITUTE
Growth inhibition of myeloid leukemia cells by troglitazone, a ligand for peroxisome proliferator activated receptor gamma, and retinoids
INTERNATIONAL JOURNAL OF ONCOLOGY
Identification of three distinct regions of deletion on the long arm of chromosome 11 in childhood acute lymphoblastic leukemia
ONCOGENE
Mutational analysis of the Hel-N1 gene in childhood acute lymphoblastic leukemia with LOH at 9p21
LEUKEMIA
Decreased expression of p33ING1 mRNA in lymphoid malignancies
AMERICAN JOURNAL OF HEMATOLOGY
Functions of cyclin A1 in the cell cycle and its interactions with transcription factor E2F-1 and the Rb family of proteins
MOLECULAR AND CELLULAR BIOLOGY
Novel 20-epi-vitamin D-3 analog combined with 9-cis-retinoic acid markedlyinhibits colony growth of prostate cancer cells
PROSTATE
p21(WAF1) expression by an activator of protein kinase C is regulated mainly at the post-transcriptional level in cells lacking p53: important role of RNA stabilization
BIOCHEMICAL JOURNAL
20-cyclopropyl-cholecalciferol vitamin D-3 analogs: A unique class of potent inhibitors of proliferation of human prostate, breast and myeloid leukemia cell lines
ANTICANCER RESEARCH
Combination therapy of a vitamin D-3 analog and all-trans-retinoic acid: Effect on human breast cancer in nude mice
ANTICANCER RESEARCH
Combined effect of vitamin D-3 analogs and paclitaxel on the growth of MCF-7 breast cancer cells in vivo
BREAST CANCER RESEARCH AND TREATMENT
Allelotyping of acute myelogenous leukemia: loss of heterozygosity at 7q31.1 (D7S486) and q33-34 (D7S498, D7S505)
LEUKEMIA RESEARCH
Ovarian cancer: Loss of heterozygosity frequently occurs in the ATM gene, but structural alterations do not occur in this gene
ONCOLOGY
CCAAT/enhancer binding protein epsilon is a potential retinoid target genein acute promyelocytic leukemia treatment
JOURNAL OF CLINICAL INVESTIGATION
Molecular cloning of transferrin receptor 2 - A new member of the transferrin receptor-like family
JOURNAL OF BIOLOGICAL CHEMISTRY
Cloning of the cyclin A1 genomic structure and characterization of the promoter region - GC boxes are essential for cell cycle-regulated transcription of the cyclin A1 gene
JOURNAL OF BIOLOGICAL CHEMISTRY
Translocon-associated protein alpha transcripts are induced by granulocyte-macrophage colony-stimulating factor and exhibit complex alternative polyadenylation
FEBS LETTERS
5,6-trans-16-ene-vitamin D-3: A new class of potent inhibitors of proliferation of prostate, breast, and myeloid leukemic cells
CANCER RESEARCH
Synergistic inhibition of prostate cancer cell lines by a 19-nor hexafluoride vitamin D-3 analogue and antiactivator protein 1 retinoid
BRITISH JOURNAL OF CANCER
Myeloid transcription factor C/EBP epsilon is involved in the positive regulation of lactoferrin gene expression in neutrophils
BLOOD
Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation
BLOOD
c-myb transactivates the human cyclin A1 promoter and induces cyclin A1 gene expression
BLOOD
1,25-dihydroxyvitamin D-3 induces differentiation of a retinoic acid-resistant acute promyelocytic leukemia cell line (UF-1) associated with expression of p21(WAF1/CIP1) and p27(KIP1)
BLOOD
Effects of novel RAR- and RXR-selective retinoids on myeloid leukemic proliferation and differentiation in vitro
BLOOD
Detailed deletion mapping of the long arm of chromosome 6 in adult T-cell leukemia
BLOOD
C/EBP epsilon directly interacts with the DNA binding domain of c-myb and cooperatively activates transcription of myeloid promoters
BLOOD
Herpesvirus 8 inclusions in primary effusion lymphoma Report of a unique case with T-cell phenotype
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
Vitamin D analogs, leukemia and WAF1
LEUKEMIA & LYMPHOMA
NOVEL VITAMIN-D-3 ANALOG (CB1093) WHEN COMBINED WITH PACLITAXEL AND CISPLATIN INHIBIT GROWTH OF MCF-7 HUMAN BREAST-CANCER CELLS IN-VIVO
International journal of oncology
IMMUNOTHERAPY AGAINST MURINE LEUKEMIA
Leukemia
Preadipocytes stimulate breast cancer cell growth
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
A NOVEL RETINOIC ACID RECEPTOR (RAR)-SELECTIVE ANTAGONIST INHIBITS DIFFERENTIATION AND APOPTOSIS OF HL-60 CELLS - IMPLICATIONS OF RAR-ALPHA-MEDIATED SIGNALS IN MYELOID LEUKEMIC-CELLS
Leukemia research
LIGANDS FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA AND RETINOIC ACID RECEPTOR INHIBIT GROWTH AND INDUCE APOPTOSIS OF HUMAN BREAST-CANCER CELLS IN-VITRO AND IN BNX MICE
Proceedings of the National Academy of Sciences of the United Statesof America
MUTATION AND EXPRESSION ANALYSIS OF THE CYCLIN-DEPENDENT KINASE INHIBITOR GENE P27 KIP1 IN PITUITARY-TUMORS/
Journal of Endocrinology
IDENTIFICATION OF TRANSCRIPTIONAL ACTIVATION AND REPRESSION DOMAINS IN HUMAN CCAAT ENHANCER-BINDING PROTEIN-EPSILON
The Journal of biological chemistry
EXPRESSION OF RETINOIC ACID RECEPTOR-BETA SENSITIZES PROSTATE-CANCER CELLS TO GROWTH-INHIBITION MEDIATED BY COMBINATIONS OF RETINOIDS AND A19-NOR HEXAFLUORIDE VITAMIN-D-3 ANALOG
Endocrinology
LI-FRAUMENI-SYNDROME AND THE ROLE OF THE P53 TUMOR-SUPPRESSOR GENE INCANCER SUSCEPTIBILITY
Clinical obstetrics and gynecology
LIGAND FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA (TROGLITAZONE) HAS POTENT ANTITUMOR EFFECT AGAINST HUMAN PROSTATE-CANCER BOTH IN-VITRO AND IN-VIVO
Cancer research
19-NOR-26,27-BISHOMO-VITAMIN-D-3 ANALOGS - A UNIQUE CLASS OF POTENT INHIBITORS OF PROLIFERATION OF PROSTATE, BREAST, AND HEMATOPOIETIC CANCER-CELLS
Cancer research
FREQUENT LOSS OF HETEROZYGOSITY ON THE LONG ARM OF CHROMOSOME-6 - IDENTIFICATION OF 2 DISTINCT REGIONS OF DELETION IN CHILDHOOD ACUTE LYMPHOBLASTIC-LEUKEMIA
Cancer research
GENETIC AND EPIGENETIC ALTERATIONS OF THE CYCLIN-DEPENDENT KINASE INHIBITORS P15(INK4B) AND P16(INK4A) IN HUMAN THYROID-CARCINOMA CELL-LINES AND PRIMARY THYROID CARCINOMAS
Cancer
THE ATM GENE AND SUSCEPTIBILITY TO CHILDHOOD T-CELL ACUTE LYMPHOBLASTIC-LEUKEMIA
British Journal of Haematology
METHYLATION OF THE P16(INK4A) GENE IN MULTIPLE-MYELOMA
British Journal of Haematology
MICROSATELLITE INSTABILITY IN ADULT T-CELL LEUKEMIA
British Journal of Haematology
GROWTH-INHIBITION OF DU-145 PROSTATE-CANCER CELLS BY A BCL-2 ANTISENSE OLIGONUCLEOTIDE IS ENHANCED BY N-(2-HYDROXYPHENYL)ALL-TRANS RETINAMIDE
British Journal of Cancer
CHROMOSOME BAND 1P36 CONTAINS A PUTATIVE TUMOR-SUPPRESSOR GENE IMPORTANT IN THE EVOLUTION OF CHRONIC MYELOCYTIC-LEUKEMIA
Blood
19-NOR VITAMIN-D ANALOGS - A NEW CLASS OF POTENT INHIBITORS OF PROLIFERATION AND INDUCERS OF DIFFERENTIATION OF HUMAN MYELOID-LEUKEMIA CELL-LINES
Blood
ALLELOTYPE ANALYSIS OF ADULT T-CELL LEUKEMIA
Blood
DETECTION AND TITRATION OF HUMAN HERPESVIRUS-8-SPECIFIC ANTIBODIES INSERA FROM BLOOD-DONORS, ACQUIRED-IMMUNODEFICIENCY-SYNDROME PATIENTS AND KAPOSIS-SARCOMA PATIENTS USING A WHOLE VIRUS ENZYME-LINKED-IMMUNOSORBENT-ASSAY
Blood
MECHANISMS OF GROWTH-CONTROL OF KAPOSIS SARCOMA-ASSOCIATED HERPES VIRUS-ASSOCIATED PRIMARY EFFUSION LYMPHOMA-CELLS
Blood
MULTIPLE-MYELOMA AND HHV8 INFECTION - RESPONSE
Blood
SEROPREVALENCE OF HHV-8 ANTIBODIES IN HIV-POSITIVE HOMOSEXUAL MEN WITHOUT KAPOSIS-SARCOMA AND THEIR CLINICAL FOLLOW-UP
AJCP. American journal of clinical pathology