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1. McNaught, KSP; Olanow, CW; Halliwell, B; Isacson, O; Jenner, P
   Failure of the ubiquitin-proteasome system in Parkinson's disease
   NATURE REVIEWS NEUROSCIENCE
   
   K.S.P. McNaught et al., "Failure of the ubiquitin-proteasome system in Parkinson's disease", NAT REV NEU, 2(8), 2001, pp. 589-594
2. Isacson, O; Costantini, L; Schumacher, JM; Cicchetti, F; Chung, S; Kim, SK
   Cell implantation therapies for Parkinson's disease using neural stem, transgenic or xenogeneic donor cells
   PARKINSONISM & RELATED DISORDERS
   
   O. Isacson et al., "Cell implantation therapies for Parkinson's disease using neural stem, transgenic or xenogeneic donor cells", PARKINS R D, 7(3), 2001, pp. 205-212
3. Isacson, O; Bjorklund, L; Pernaute, RS
   Parkinson's disease: interpretations of transplantation study are erroneous
   NATURE NEUROSCIENCE
   
   O. Isacson et al., "Parkinson's disease: interpretations of transplantation study are erroneous", NAT NEUROSC, 4(6), 2001, pp. 553-553
4. Hwang, DY; Carlezon, WA; Isacson, O; Kim, KS
   A high-efficiency synthetic expression selectively promoter that drives transgene in noradrenergic neurons
   HUMAN GENE THERAPY
   
   D.Y. Hwang et al., "A high-efficiency synthetic expression selectively promoter that drives transgene in noradrenergic neurons", HUM GENE TH, 12(14), 2001, pp. 1731-1740
5. Costantini, LC; Cole, D; Isacson, O
   Immunophilin ligands can prevent progressive dopaminergic degeneration in animal models of Parkinson's disease
   EUROPEAN JOURNAL OF NEUROSCIENCE
   
   L.C. Costantini et al., "Immunophilin ligands can prevent progressive dopaminergic degeneration in animal models of Parkinson's disease", EUR J NEURO, 13(6), 2001, pp. 1085-1092
6. Holm, KH; Cicchetti, F; Bjorklund, L; Boonman, Z; Tandon, P; Costantini, LC; Deacon, TW; Huang, X; Chen, DF; Isacson, O
   Enhanced axonal growth from fetal human bcl-2 transgenic mouse dopamine neurons transplanted to the adult rat striatum
   NEUROSCIENCE
   
   K.H. Holm et al., "Enhanced axonal growth from fetal human bcl-2 transgenic mouse dopamine neurons transplanted to the adult rat striatum", NEUROSCIENC, 104(2), 2001, pp. 397-405
7. Browne, SE; Lin, L; Mattsson, A; Georgievska, B; Isacson, O
   Selective antibody-induced cholinergic cell and synapse loss produce sustained hippocampal and cortical hypometabolism with correlated cognitive deficits
   EXPERIMENTAL NEUROLOGY
   
   S.E. Browne et al., "Selective antibody-induced cholinergic cell and synapse loss produce sustained hippocampal and cortical hypometabolism with correlated cognitive deficits", EXP NEUROL, 170(1), 2001, pp. 36-47
8. Emilien, G; Ponchon, M; Caldas, C; Isacson, O; Maloteaux, JM
   Impact of genomics on drug discovery and clinical medicine
   QJM-MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS
   
   G. Emilien et al., "Impact of genomics on drug discovery and clinical medicine", QJM-MON J A, 93(7), 2000, pp. 391-423
9. Costantini, LC; Jacoby, DR; Wang, S; Fraefel, C; Breakefield, XO; Isacson, O
   Gene transfer to the nigrostriatal system by hybrid herpes simplex virus/adeno-associated virus amplicon vectors (vol 10, pg 2481, 1999)
   HUMAN GENE THERAPY
   
   L.C. Costantini et al., "Gene transfer to the nigrostriatal system by hybrid herpes simplex virus/adeno-associated virus amplicon vectors (vol 10, pg 2481, 1999)", HUM GENE TH, 11(6), 2000, pp. 981-981
10. Costantini, LC; Bakowska, JC; Breakefield, XO; Isacson, O
    Gene therapy in the CNS
    GENE THERAPY
    
    L.C. Costantini et al., "Gene therapy in the CNS", GENE THER, 7(2), 2000, pp. 93-109
11. Haque, NSK; Isacson, O
    Neurotrophic factors NGF and FGF-2 alter levels of huntingtin (IT15) in striatal neuronal cell cultures
    CELL TRANSPLANTATION
    
    N.S.K. Haque e O. Isacson, "Neurotrophic factors NGF and FGF-2 alter levels of huntingtin (IT15) in striatal neuronal cell cultures", CELL TRANSP, 9(5), 2000, pp. 623-627
12. Fink, JS; Schumacher, JM; Ellias, SL; Palmer, EP; Saint-Hilaire, M; Shannon, K; Penn, R; Starr, P; VanHorne, C; Kott, HS; Dempsey, PK; Fischman, AJ; Raineri, R; Manhart, C; Dinsmore, J; Isacson, O
    Porcine xenografts in parkinson's disease and Huntington's disease patients: Preliminary results
    CELL TRANSPLANTATION
    
    J.S. Fink et al., "Porcine xenografts in parkinson's disease and Huntington's disease patients: Preliminary results", CELL TRANSP, 9(2), 2000, pp. 273-278
13. Costantini, LC; Isacson, O
    Neuroimmunophilin ligand enhances neurite outgrowth and effect of fetal dopamine transplants
    NEUROSCIENCE
    
    L.C. Costantini e O. Isacson, "Neuroimmunophilin ligand enhances neurite outgrowth and effect of fetal dopamine transplants", NEUROSCIENC, 100(3), 2000, pp. 515-520
14. Schumacher, JM; Ellias, SA; Palmer, EP; Kott, HS; Dinsmore, J; Dempsey, PK; Fischman, AJ; Thomas, C; Feldman, RG; Kassissieh, S; Raineri, R; Manhart, C; Penney, D; Fink, JS; Isacson, O
    Transplantation of embryonic porcine mesencephalic tissue in patients withPD
    NEUROLOGY
    
    J.M. Schumacher et al., "Transplantation of embryonic porcine mesencephalic tissue in patients withPD", NEUROLOGY, 54(5), 2000, pp. 1042-1050
15. Freeman, TB; Cicchetti, F; Hauser, RA; Deacon, TW; Li, XJ; Hersch, SM; Nauert, GM; Sanberg, PR; Kordower, JH; Saporta, S; Isacson, O
    Transplanted fetal striatum in Huntington's disease: Phenotypic development and lack of pathology
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    T.B. Freeman et al., "Transplanted fetal striatum in Huntington's disease: Phenotypic development and lack of pathology", P NAS US, 97(25), 2000, pp. 13877-13882
16. Costantini, LC; Isacson, O
    Immunophilin ligands and GDNF enhance neurite branching or elongation fromdeveloping dopamine neurons in culture
    EXPERIMENTAL NEUROLOGY
    
    L.C. Costantini e O. Isacson, "Immunophilin ligands and GDNF enhance neurite branching or elongation fromdeveloping dopamine neurons in culture", EXP NEUROL, 164(1), 2000, pp. 60-70
17. Isacson, O; Costantini, LC; Galpern, WR
    Molecules for neuroprotection and regeneration in animal models of Parkinson's disease
    CENTRAL NERVOUS SYSTEM DISEASES
    
    O. Isacson et al., "Molecules for neuroprotection and regeneration in animal models of Parkinson's disease", CONT NEUROS, 2000, pp. 187-207
18. Costantini, LC; Jacoby, DR; Wang, S; Fraefel, C; Breakefield, XO; Isacson, O
    Gene transfer to the nigrostriatal system by hybrid herpes simplex virus/adeno-associated virus amplicon vectors
    HUMAN GENE THERAPY
    
    L.C. Costantini et al., "Gene transfer to the nigrostriatal system by hybrid herpes simplex virus/adeno-associated virus amplicon vectors", HUM GENE TH, 10(15), 1999, pp. 2481-2494
19. Isacson, O
    The neurobiology and neurogenetics of stem cells
    BRAIN PATHOLOGY
    
    O. Isacson, "The neurobiology and neurogenetics of stem cells", BRAIN PATH, 9(3), 1999, pp. 495-498
20. Deacon, T; Whatley, B; LeBlanc, C; Lin, L; Isacson, O
    Pig fetal septal neurons implanted into the hippocampus of aged or cholinergic deafferented rats grow axons and form cross-species synapses in appropriate target regions
    CELL TRANSPLANTATION
    
    T. Deacon et al., "Pig fetal septal neurons implanted into the hippocampus of aged or cholinergic deafferented rats grow axons and form cross-species synapses in appropriate target regions", CELL TRANSP, 8(1), 1999, pp. 111-129
21. LeBlanc, CJ; Deacon, TW; Whatley, BR; Dinsmore, J; Lin, L; Isacson, O
    Morris water maze analysis of 192-IgG-saporin-lesioned rats and porcine cholinergic transplants to the hippocampus
    CELL TRANSPLANTATION
    
    C.J. LeBlanc et al., "Morris water maze analysis of 192-IgG-saporin-lesioned rats and porcine cholinergic transplants to the hippocampus", CELL TRANSP, 8(1), 1999, pp. 131-142
22. Chen, YI; Brownell, AL; Galpern, W; Isacson, O; Bogdanov, M; Beal, MF; Livni, E; Rosen, BR; Jenkins, BG
    Detection of dopaminergic cell loss and neural transplantation using pharmacological MRI, PET and behavioral assessment
    NEUROREPORT
    
    Y.I. Chen et al., "Detection of dopaminergic cell loss and neural transplantation using pharmacological MRI, PET and behavioral assessment", NEUROREPORT, 10(14), 1999, pp. 2881-2886
23. Brownell, AL; Jenkins, BG; Isacson, O
    Dopamine imaging markers and predictive mathematical models for progressive degeneration in Parkinson's disease
    BIOMEDICINE & PHARMACOTHERAPY
    
    A.L. Brownell et al., "Dopamine imaging markers and predictive mathematical models for progressive degeneration in Parkinson's disease", BIOMED PHAR, 53(3), 1999, pp. 131-140
24. Holm, K; Isacson, O
    Factors intrinsic to the neuron can induce and maintain its ability to promote axonal outgrowth: a role for BCL2?
    TRENDS IN NEUROSCIENCES
    
    K. Holm e O. Isacson, "Factors intrinsic to the neuron can induce and maintain its ability to promote axonal outgrowth: a role for BCL2?", TRENDS NEUR, 22(6), 1999, pp. 269-273
25. Lin, L; Georgievska, B; Mattsson, A; Isacson, O
    Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    L. Lin et al., "Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation", P NAS US, 96(21), 1999, pp. 12108-12113
26. Isacson, O; Sladek, JR
    Cellular and molecular treatments of neurological diseases
    EXPERIMENTAL NEUROLOGY
    
    O. Isacson e J.R. Sladek, "Cellular and molecular treatments of neurological diseases", EXP NEUROL, 159(1), 1999, pp. 1-3
27. Kordower, JH; Isacson, O; Emerich, DF
    Cellular delivery of trophic factors for the treatment of Huntington's disease: Is neuroprotection possible?
    EXPERIMENTAL NEUROLOGY
    
    J.H. Kordower et al., "Cellular delivery of trophic factors for the treatment of Huntington's disease: Is neuroprotection possible?", EXP NEUROL, 159(1), 1999, pp. 4-20
28. Boonman, Z; Isacson, O
    Apoptosis in neuronal development and transplantation: Role of caspases and trophic factors
    EXPERIMENTAL NEUROLOGY
    
    Z. Boonman e O. Isacson, "Apoptosis in neuronal development and transplantation: Role of caspases and trophic factors", EXP NEUROL, 156(1), 1999, pp. 1-15
29. BROWNELL AL; JENKINS BG; ELMALEH DR; DEACON TW; SPEALMAN RD; ISACSON O
    COMBINED PET MRS BRAIN STUDIES SHOW DYNAMIC AND LONG-TERM PHYSIOLOGICAL-CHANGES IN A PRIMATE MODEL OF PARKINSON-DISEASE/
    Nature medicine
    
    A.L. Brownell et al., "COMBINED PET MRS BRAIN STUDIES SHOW DYNAMIC AND LONG-TERM PHYSIOLOGICAL-CHANGES IN A PRIMATE MODEL OF PARKINSON-DISEASE/", Nature medicine, 4(11), 1998, pp. 1308-1312
30. COSTANTINI LC; CHATURVEDI P; ARMISTEAD DM; MCCAFFREY PG; DEACON TW; ISACSON O
    A NOVEL IMMUNOPHILIN LIGAND - DISTINCT BRANCHING EFFECTS ON DOPAMINERGIC-NEURONS IN CULTURE AND NEUROTROPHIC ACTIONS AFTER ORAL-ADMINISTRATION IN AN ANIMAL-MODEL OF PARKINSONS-DISEASE
    Neurobiology of disease
    
    L.C. Costantini et al., "A NOVEL IMMUNOPHILIN LIGAND - DISTINCT BRANCHING EFFECTS ON DOPAMINERGIC-NEURONS IN CULTURE AND NEUROTROPHIC ACTIONS AFTER ORAL-ADMINISTRATION IN AN ANIMAL-MODEL OF PARKINSONS-DISEASE", Neurobiology of disease, 5(2), 1998, pp. 97-106
31. LIN L; LEBLANC CJ; DEACON TW; ISACSON O
    CHRONIC COGNITIVE DEFICITS AND AMYLOID PRECURSOR PROTEIN ELEVATION AFTER SELECTIVE IMMUNOTOXIN LESIONS OF THE BASAL FOREBRAIN CHOLINERGIC SYSTEM
    NeuroReport
    
    L. Lin et al., "CHRONIC COGNITIVE DEFICITS AND AMYLOID PRECURSOR PROTEIN ELEVATION AFTER SELECTIVE IMMUNOTOXIN LESIONS OF THE BASAL FOREBRAIN CHOLINERGIC SYSTEM", NeuroReport, 9(3), 1998, pp. 547-552
32. BROWNELL AL; LIVNI E; GALPERN W; ISACSON O
    IN-VIVO PET IMAGING IN RAT OF DOPAMINE TERMINALS REVEALS FUNCTIONAL NEURAL TRANSPLANTS
    Annals of neurology
    
    A.L. Brownell et al., "IN-VIVO PET IMAGING IN RAT OF DOPAMINE TERMINALS REVEALS FUNCTIONAL NEURAL TRANSPLANTS", Annals of neurology, 43(3), 1998, pp. 387-390
33. BROWNELL AL; CHEN YCI; GALPERN WR; LIVNI E; BOGDANOV M; BEAL MF; ISACSON O; ROSEN BR; JENKINS BG
    ASSESSMENT OF DOPAMINERGIC NEUROTRANSMITTERS WITH WIN 35,428-COMPOUND(CFT) USING PET, PHARMACOLOGICAL MRI (PHMRI), MICRODIALYSIS AND BEHAVIORAL-STUDIES
    The Journal of nuclear medicine
    
    A.L. Brownell et al., "ASSESSMENT OF DOPAMINERGIC NEUROTRANSMITTERS WITH WIN 35,428-COMPOUND(CFT) USING PET, PHARMACOLOGICAL MRI (PHMRI), MICRODIALYSIS AND BEHAVIORAL-STUDIES", The Journal of nuclear medicine, 39(5), 1998, pp. 205-205
34. ELLIAS SA; PALMER EP; KOTT HS; THOMAS C; ISACSON O; SCHUMACHER J; FINK JS
    TRANSPLANTATION OF FETAL PORCINE VENTRAL MESENCEPHALIC CELLS FOR TREATMENT OF PARKINSONS-DISEASE - ONE-YEAR SAFETY AND EFFICACY RESULTS
    Neurology
    
    S.A. Ellias et al., "TRANSPLANTATION OF FETAL PORCINE VENTRAL MESENCEPHALIC CELLS FOR TREATMENT OF PARKINSONS-DISEASE - ONE-YEAR SAFETY AND EFFICACY RESULTS", Neurology, 50(4), 1998, pp. 10007-10007
35. STHILLAIRE M; SHANNON K; SCHUMACHER J; STARR P; PENN R; VANHORNE C; ISACSON O; FINK JS
    TRANSPLANTATION OF FETAL PORCINE STRIATAL CELLS IN HUNTINGTONS-DISEASE - PRELIMINARY SAFETY AND EFFICACY RESULTS
    Neurology
    
    M. Sthillaire et al., "TRANSPLANTATION OF FETAL PORCINE STRIATAL CELLS IN HUNTINGTONS-DISEASE - PRELIMINARY SAFETY AND EFFICACY RESULTS", Neurology, 50(4), 1998, pp. 10008-10008
36. COSTANTINI LC; CHATURVEDI P; ARMISTEAD DM; MCCAFFREY PG; DEACON TW; ISACSON O
    A NOVEL IMMUNOPHILIN LIGAND - DISTINCT BRANCHING EFFECTS ON DOPAMINERGIC-NEURONS IN CULTURE AND NEUROTROPHIC ACTIONS AFTER ORAL-ADMINISTRATION IN AN ANIMAL-MODEL OF PARKINSONS-DISEASE
    Experimental neurology
    
    L.C. Costantini et al., "A NOVEL IMMUNOPHILIN LIGAND - DISTINCT BRANCHING EFFECTS ON DOPAMINERGIC-NEURONS IN CULTURE AND NEUROTROPHIC ACTIONS AFTER ORAL-ADMINISTRATION IN AN ANIMAL-MODEL OF PARKINSONS-DISEASE", Experimental neurology, 153(2), 1998, pp. 382-382
37. DEACON T; LEBLANC C; LIN L; DINSMORE J; ISACSON O
    FUNCTIONAL AND STRUCTURAL-ANALYSIS OF TRANSPLANTED CHOLINERGIC PORCINE NEURONS - GROWTH OF AXONS AND SYNAPSES IN SPECIFIC HIPPOCAMPAL TARGETS OF NGFR-SAPORIN LESIONED RATS
    Experimental neurology
    
    T. Deacon et al., "FUNCTIONAL AND STRUCTURAL-ANALYSIS OF TRANSPLANTED CHOLINERGIC PORCINE NEURONS - GROWTH OF AXONS AND SYNAPSES IN SPECIFIC HIPPOCAMPAL TARGETS OF NGFR-SAPORIN LESIONED RATS", Experimental neurology, 153(2), 1998, pp. 390-390
38. DEACON T; DINSMORE J; COSTANTINI LC; RATLIFF J; ISACSON O
    BLASTULA-STAGE STEM-CELLS CAN DIFFERENTIATE INTO DOPAMINERGIC AND SEROTONERGIC NEURONS AFTER TRANSPLANTATION
    Experimental neurology
    
    T. Deacon et al., "BLASTULA-STAGE STEM-CELLS CAN DIFFERENTIATE INTO DOPAMINERGIC AND SEROTONERGIC NEURONS AFTER TRANSPLANTATION", Experimental neurology, 149(1), 1998, pp. 28-41
39. HAQUE NSK; BORGHESANI P; ISACSON O
    THERAPEUTIC STRATEGIES FOR HUNTINGTONS-DISEASE BASED ON A MOLECULAR UNDERSTANDING OF THE DISORDER
    Molecular medicine today
    
    N.S.K. Haque et al., "THERAPEUTIC STRATEGIES FOR HUNTINGTONS-DISEASE BASED ON A MOLECULAR UNDERSTANDING OF THE DISORDER", Molecular medicine today, 3(4), 1997, pp. 175-183
40. ISACSON O; BREAKEFIELD XO
    BENEFITS AND RISKS OF HOSTING ANIMAL-CELLS IN THE HUMAN BRAIN
    Nature medicine
    
    O. Isacson e X.O. Breakefield, "BENEFITS AND RISKS OF HOSTING ANIMAL-CELLS IN THE HUMAN BRAIN", Nature medicine, 3(9), 1997, pp. 964-969
41. SCHUMACHER JM; ISACSON O
    NEURONAL XENOTRANSPLANTATION IN PARKINSONS-DISEASE
    Nature medicine
    
    J.M. Schumacher e O. Isacson, "NEURONAL XENOTRANSPLANTATION IN PARKINSONS-DISEASE", Nature medicine, 3(5), 1997, pp. 474-475
42. DEACON T; SCHUMACHER J; DINSMORE J; THOMAS C; PALMER P; KOTT S; EDGE A; PENNEY D; KASSISSIEH S; DEMPSEY P; ISACSON O
    HISTOLOGICAL EVIDENCE OF FETAL PIG NEURAL CELL-SURVIVAL AFTER TRANSPLANTATION INTO A PATIENT WITH PARKINSONS-DISEASE
    Nature medicine
    
    T. Deacon et al., "HISTOLOGICAL EVIDENCE OF FETAL PIG NEURAL CELL-SURVIVAL AFTER TRANSPLANTATION INTO A PATIENT WITH PARKINSONS-DISEASE", Nature medicine, 3(3), 1997, pp. 350-353
43. FREED WJ; ISACSON O
    A SPECIAL ISSUE BASED ON THE 3RD ANNUAL CONFERENCE OF THE AMERICAN-SOCIETY-FOR-NEURAL-TRANSPLANTATION, 1996 - INTRODUCTION
    Cell transplantation
    
    W.J. Freed e O. Isacson, "A SPECIAL ISSUE BASED ON THE 3RD ANNUAL CONFERENCE OF THE AMERICAN-SOCIETY-FOR-NEURAL-TRANSPLANTATION, 1996 - INTRODUCTION", Cell transplantation, 6(3), 1997, pp. 201-202
44. HAQUE NSK; LEBLANC CJ; ISACSON O
    DIFFERENTIAL DISSECTION OF THE RAT E16 VENTRAL MESENCEPHALON AND SURVIVAL AND REINNERVATION OF THE 6-OHDA-LESIONED STRIATUM BY A SUBSET OF ALDEHYDE DEHYDROGENASE-POSITIVE TH NEURONS
    Cell transplantation
    
    N.S.K. Haque et al., "DIFFERENTIAL DISSECTION OF THE RAT E16 VENTRAL MESENCEPHALON AND SURVIVAL AND REINNERVATION OF THE 6-OHDA-LESIONED STRIATUM BY A SUBSET OF ALDEHYDE DEHYDROGENASE-POSITIVE TH NEURONS", Cell transplantation, 6(3), 1997, pp. 239-248
45. COSTANTINI LC; LIN L; ISACSON O
    MEDIAL FETAL VENTRAL MESENCEPHALON - A PREFERRED SOURCE FOR DOPAMINE NEURON GRAFTS
    NeuroReport
    
    L.C. Costantini et al., "MEDIAL FETAL VENTRAL MESENCEPHALON - A PREFERRED SOURCE FOR DOPAMINE NEURON GRAFTS", NeuroReport, 8(9-10), 1997, pp. 2253-2257
46. CHEN YCI; GALPERN WR; BROWNELL AL; MATTHEWS RT; BOGDANOV M; ISACSON O; KELTNER JR; BEAL MF; ROSEN BR; JENKINS BG
    DETECTION OF DOPAMINERGIC NEUROTRANSMITTER ACTIVITY USING PHARMACOLOGICAL MRI - CORRELATION WITH PET, MICRODIALYSIS, AND BEHAVIORAL-DATA
    Magnetic resonance in medicine
    
    Y.C.I. Chen et al., "DETECTION OF DOPAMINERGIC NEUROTRANSMITTER ACTIVITY USING PHARMACOLOGICAL MRI - CORRELATION WITH PET, MICRODIALYSIS, AND BEHAVIORAL-DATA", Magnetic resonance in medicine, 38(3), 1997, pp. 389-398
47. ISACSON O; DEACON T
    NEURAL TRANSPLANTATION STUDIES REVEAL THE BRAINS CAPACITY FOR CONTINUOUS RECONSTRUCTION
    Trends in neurosciences
    
    O. Isacson e T. Deacon, "NEURAL TRANSPLANTATION STUDIES REVEAL THE BRAINS CAPACITY FOR CONTINUOUS RECONSTRUCTION", Trends in neurosciences, 20(10), 1997, pp. 477-482
48. HAQUE N; ISACSON O
    ANTISENSE GENE-THERAPY FOR NEURODEGENERATIVE DISEASE
    Experimental neurology
    
    N. Haque e O. Isacson, "ANTISENSE GENE-THERAPY FOR NEURODEGENERATIVE DISEASE", Experimental neurology, 144(1), 1997, pp. 139-146
49. ISACSON O; KORDOWER JH
    THE NEUROBIOLOGICAL AND CLINICAL POTENTIAL OF NEURAL CELL TRANSPLANTATION - SPECIAL ISSUE BASED ON THE MEETING OF THE AMERICAN-SOCIETY-FOR-NEURAL-TRANSPLANTATION, 1995
    Cell transplantation
    
    O. Isacson e J.H. Kordower, "THE NEUROBIOLOGICAL AND CLINICAL POTENTIAL OF NEURAL CELL TRANSPLANTATION - SPECIAL ISSUE BASED ON THE MEETING OF THE AMERICAN-SOCIETY-FOR-NEURAL-TRANSPLANTATION, 1995", Cell transplantation, 5(2), 1996, pp. 123-125
50. DINSMORE J; RATLIFF J; DEACON T; PAKZABAN P; JACOBY D; GALPERN W; ISACSON O
    EMBRYONIC STEM-CELLS DIFFERENTIATED IN-VITRO AS A NOVEL SOURCE OF CELLS FOR TRANSPLANTATION
    Cell transplantation
    
    J. Dinsmore et al., "EMBRYONIC STEM-CELLS DIFFERENTIATED IN-VITRO AS A NOVEL SOURCE OF CELLS FOR TRANSPLANTATION", Cell transplantation, 5(2), 1996, pp. 131-143
51. GALPERN WR; FRIM DM; TATTER SB; ALTAR CA; BEAL MF; ISACSON O
    CELL-MEDIATED DELIVERY OF BRAIN-DERIVED NEUROTROPHIC FACTOR ENHANCES DOPAMINE LEVELS IN AN MPP-NIGRA DEGENERATION( RAT MODEL OF SUBSTANTIA)
    Cell transplantation
    
    W.R. Galpern et al., "CELL-MEDIATED DELIVERY OF BRAIN-DERIVED NEUROTROPHIC FACTOR ENHANCES DOPAMINE LEVELS IN AN MPP-NIGRA DEGENERATION( RAT MODEL OF SUBSTANTIA)", Cell transplantation, 5(2), 1996, pp. 225-232
52. GALPERN WR; MATTHEWS RT; BEAL MF; ISACSON O
    NGF ATTENUATES 3-NITROTYROSINE FORMATION IN A 3-NP MODEL OF HUNTINGTONS-DISEASE
    NeuroReport
    
    W.R. Galpern et al., "NGF ATTENUATES 3-NITROTYROSINE FORMATION IN A 3-NP MODEL OF HUNTINGTONS-DISEASE", NeuroReport, 7(15-17), 1996, pp. 2639-2642
53. ISACSON O; DEACON TW
    SPECIFIC AXON GUIDANCE FACTORS PERSIST IN THE ADULT BRAIN AS DEMONSTRATED BY PIG NEUROBLASTS TRANSPLANTED TO THE RAT
    Neuroscience
    
    O. Isacson e T.W. Deacon, "SPECIFIC AXON GUIDANCE FACTORS PERSIST IN THE ADULT BRAIN AS DEMONSTRATED BY PIG NEUROBLASTS TRANSPLANTED TO THE RAT", Neuroscience, 75(3), 1996, pp. 827-837
54. BROWNELL AL; JENKINS B; BURNS L; TATTER S; ELMALEH DR; LIVNI E; DEACON T; BROWNELL GL; ISACSON O
    USING OF PET AND MRS TECHNIQUES TO EVALUATE NEURAL DEGENERATION AND GRAFT-SURVIVAL IN PRIMATE PARKINSON DISEASE-MODEL
    The Journal of nuclear medicine
    
    A.L. Brownell et al., "USING OF PET AND MRS TECHNIQUES TO EVALUATE NEURAL DEGENERATION AND GRAFT-SURVIVAL IN PRIMATE PARKINSON DISEASE-MODEL", The Journal of nuclear medicine, 37(5), 1996, pp. 254-254
55. DINSMORE JH; PAKZABAN P; DEACON TW; BURNS L; ISACSON O
    SURVIVAL OF TRANSPLANTED PORCINE NEURAL CELLS TREATED WITH F(AB')(2) ANTIBODY FRAGMENTS DIRECTED AGAINST DONOR MHC CLASS-I IN A RODENT MODEL
    Transplantation proceedings
    
    J.H. Dinsmore et al., "SURVIVAL OF TRANSPLANTED PORCINE NEURAL CELLS TREATED WITH F(AB')(2) ANTIBODY FRAGMENTS DIRECTED AGAINST DONOR MHC CLASS-I IN A RODENT MODEL", Transplantation proceedings, 28(2), 1996, pp. 817-818
56. GALPERN WR; BURNS LH; DEACON TW; DINSMORE J; ISACSON O
    XENOTRANSPLANTATION OF PORCINE FETAL VENTRAL MESENCEPHALON IN A RAT MODEL OF PARKINSONS-DISEASE - FUNCTIONAL RECOVERY AND GRAFT MORPHOLOGY
    Experimental neurology
    
    W.R. Galpern et al., "XENOTRANSPLANTATION OF PORCINE FETAL VENTRAL MESENCEPHALON IN A RAT MODEL OF PARKINSONS-DISEASE - FUNCTIONAL RECOVERY AND GRAFT MORPHOLOGY", Experimental neurology, 140(1), 1996, pp. 1-13
57. ISACSON O; DEACON TW; PAKZABAN P; GALPERN WR; DINSMORE J; BURNS LH
    TRANSPLANTED XENOGENEIC NEURAL CELLS IN NEURODEGENERATIVE DISEASE-MODELS EXHIBIT REMARKABLE AXONAL TARGET SPECIFICITY AND DISTINCT GROWTH-PATTERNS OF GLIAL AND AXONAL FIBERS
    Nature medicine
    
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58. FREEMAN TB; SANBERG PR; ISACSON O
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59. GARCIA AR; DEACON TW; DINSMORE J; ISACSON O
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60. TATTER SB; GALPERN WR; HOOGEVEEN AT; ISACSON O
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61. ISACSON O; FRIM DM; GALPERN WR; TATTER SB; BREAKEFIELD XO; SCHUMACHER JM
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    Restorative neurology and neuroscience
    
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62. PAKZABAN P; DEACON TW; BURNS LH; DINSMORE J; ISACSON O
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63. PAKZABAN P; DEACON TW; BURNS LH; DINSMORE J; ISACSON O
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64. BURNS LH; PAKZABAN P; DEACON TW; BROWNELL AL; TATTER SB; JENKINS BG; ISACSON O
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    Neuroscience
    
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65. ISACSON O
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    Science
    
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66. DINSMORE JH; DEACON T; PAKZABAN P; RATLIFF J; ISACSON O
    NEURONS DIFFERENTIATED IN-VITRO FROM PLURIPOTENT EMBRYONIC STEM-CELLSFOR CNS TRANSPLANTATION - IN-VITRO CHARACTERIZATION AND TRANSPLANTATION INTO RODENTS
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67. GALPERN WR; BURNS LH; DEACON TW; TATTER SB; DINSMORE J; ISACSON O
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68. ISACSON O; DEACON TW; GALPERN WR; BURNS LH; DINSMORE J; PAKZABAN P
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69. ANDERSEN JK; FRIM DM; ISACSON O; BREAKEFIELD XO
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70. PAKZABAN P; GELLER AI; ISACSON O
    EFFECT OF EXOGENOUS NERVE GROWTH-FACTOR ON NEUROTOXICITY OF AND NEURONAL GENE DELIVERY BY A HERPES-SIMPLEX AMPLICON VECTOR IN THE RAT-BRAIN
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71. ISACSON O
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    Annals of neurology
    
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72. PAKZABAN P; ISACSON O
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    Neuroscience
    
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73. ISACSON O
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    Trends in neurosciences
    
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74. ELMALEH DR; BROWNELL AL; SHOUP TM; ISACSON O; FISCHMAN AJ; MADRAS B
    PET IMAGING OF [11C]3B-ARYLTROPANE-2B-CARBOXYLIC ESTER ANALOGS IN MPTP-TREATED MONKEYS
    The Journal of nuclear medicine
    
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75. UHLER TA; FRIM DM; PAKZABAN P; ISACSON O; SIESJO BK; YOUNG W
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    Neurosurgery
    
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76. FRIM DM; UHLER TA; GALPERN WR; BEAL MF; BREAKEFIELD XO; ISACSON O
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77. DAVAR G; KRAMER MF; GARBER D; ROCA AL; ANDERSEN JK; BEBRIN W; COEN DM; KOSZVNENCHAK M; KNIPE DM; BREAKEFIELD XO; ISACSON O
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78. DEACON TW; PAKZABAN P; BURNS LH; DINSMORE J; ISACSON O
    CYTOARCHITECTONIC DEVELOPMENT, AXON GLIA RELATIONSHIPS, AND LONG-DISTANCE AXON GROWTH OF PORCINE STRIATAL XENOGRAFTS IN RATS
    Experimental neurology
    
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79. FRIM DM; WULLNER U; BEAL MF; ISACSON O
    IMPLANTED NGF-PRODUCING FIBROBLASTS INDUCE CATALASE AND MODIFY ATP LEVELS BUT DO NOT AFFECT GLUTAMATE-RECEPTOR BINDING OR NMDA RECEPTOR EXPRESSION IN THE RAT STRIATUM
    Experimental neurology
    
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80. WULLNER U; PAKZABAN P; BROWNELL AL; HANTRAYE P; BURNS L; SHOUP T; ELMALEH D; PETTO AJ; SPEALMAN RD; BROWNELL GL; ISACSON O
    DOPAMINE TERMINAL LOSS AND ONSET OF MOTOR SYMPTOMS IN MPTP-TREATED MONKEYS - A POSITRON EMISSION TOMOGRAPHY STUDY WITH C-11 CFT
    Experimental neurology
    
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81. BROWNELL AL; HANTRAYE P; WULLNER U; HAMBERG L; SHOUP T; ELMALEH DR; FRIM DM; MADRAS BK; BROWNELL GL; ROSEN BR; ISACSON O
    PET-BASED AND MRI-BASED ASSESSMENT OF GLUCOSE-UTILIZATION, DOPAMINE-RECEPTOR BINDING, AND HEMODYNAMIC-CHANGES AFTER LESIONS TO THE CAUDATE-PUTAMEN IN PRIMATES
    Experimental neurology
    
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82. DEACON TW; PAKZABAN P; ISACSON O
    THE LATERAL GANGLIONIC EMINENCE IS THE ORIGIN OF CELLS COMMITTED TO STRIATAL PHENOTYPES - NEURAL TRANSPLANTATION AND DEVELOPMENTAL EVIDENCE
    Brain research
    
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83. ANDERSEN JK; FRIM DM; ISACSON O; BEAL MF; BREAKEFIELD XO
    ELEVATION OF NEURONAL MAO-B ACTIVITY IN A TRANSGENIC MOUSE MODEL DOESNOT INCREASE SENSITIVITY TO THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP)
    Brain research
    
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84. BURNS LH; SATO K; WULLNER U; ISACSON O
    INTRA-NIGRA INFUSION OF AMPA ATTENUATES DOPAMINE-DEPENDENT ROTATION IN THE RAT
    NeuroReport
    
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85. FRIM DM; YEE WM; ISACSON O
    NGF REDUCES STRIATAL EXCITOTOXIC NEURONAL LOSS WITHOUT AFFECTING CONCURRENT NEURONAL STRESS
    NeuroReport
    
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86. FRIM DM; SIMPSON J; UHLER TA; SHORT MP; BOSSI SR; BREAKEFIELD XO; ISACSON O
    STRIATAL DEGENERATION INDUCED BY MITOCHONDRIAL BLOCKADE IS PREVENTED BY BIOLOGICALLY DELIVERED NGF
    Journal of neuroscience research
    
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87. ANDERSEN JK; FRIM DM; ISACSON O; BREAKEFIELD XO
    HERPESVIRUS-MEDIATED GENE DELIVERY INTO THE RAT-BRAIN - SPECIFICITY AND EFFICIENCY OF THE NEURON-SPECIFIC ENOLASE PROMOTER
    Cellular and molecular neurobiology
    
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88. BROWNELL AL; SHOUP T; WULLNER U; ELMALEH D; PAKZABAN P; FRIM DM; BROWNELL G; ISACSON O
    INVIVO VISUALIZATION OF STRIATAL TRANSPLANTS IN A PRIMATE MODEL OF HUNTINGTONS-DISEASE (HD)
    The Journal of nuclear medicine
    
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89. FRIM DM; ISACSON O
    NEURONAL PROTECTION AGAINST EXCITOTOXICITY - RESPONSE
    Journal of neurosurgery
    
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90. WULLNER U; BROUILLET E; ISACSON O; YOUNG AB; PENNEY JB
    GLUTAMATE-RECEPTOR BINDING-SITES IN MPTP-TREATED MICE
    Experimental neurology
    
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91. SIMPSON JR; ISACSON O
    MITOCHONDRIAL IMPAIRMENT REDUCES THE THRESHOLD FOR INVIVO NMDA-MEDIATED NEURONAL DEATH IN THE STRIATUM
    Experimental neurology
    
    J.R. Simpson e O. Isacson, "MITOCHONDRIAL IMPAIRMENT REDUCES THE THRESHOLD FOR INVIVO NMDA-MEDIATED NEURONAL DEATH IN THE STRIATUM", Experimental neurology, 121(1), 1993, pp. 57-64
92. PAKZABAN P; DEACON TW; BURNS LH; ISACSON O
    INCREASED PROPORTION OF ACETYLCHOLINESTERASE-RICH ZONES AND IMPROVED MORPHOLOGICAL INTEGRATION IN HOST STRIATUM OF FETAL GRAFTS DERIVED FROM THE LATERAL BUT NOT THE MEDIAL GANGLIONIC EMINENCE
    Experimental Brain Research
    
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93. YEE WM; FRIM DM; ISACSON O
    RELATIONSHIPS BETWEEN STRESS PROTEIN INDUCTION AND NMDA-MEDIATED NEURONAL DEATH IN THE ENTORHINAL CORTEX
    Experimental Brain Research
    
    W.M. Yee et al., "RELATIONSHIPS BETWEEN STRESS PROTEIN INDUCTION AND NMDA-MEDIATED NEURONAL DEATH IN THE ENTORHINAL CORTEX", Experimental Brain Research, 94(2), 1993, pp. 193-202