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    1. Saito, S; Iida, A; Sekine, A; Miura, Y; Sakamoto, T; Ogawa, C; Kawauchi, S; Higuchi, S; Nakamura, Y
      Identification of 197 genetic variations in six human methyltransferase genes in the Japanese population

      JOURNAL OF HUMAN GENETICS
    2. Sekine, A; Saito, S; Iida, A; Mitsunobu, Y; Higuchi, S; Harigae, S; Nakamura, Y
      Identification of single-nucleotide polymorphisms (SNPs) of human N-acetyltransferase genes NAT1, NAT2, AANAT, ARD1, and L1CAM in the Japanese population

      JOURNAL OF HUMAN GENETICS
    3. Asaka, T; Ikeuchi, K; Okino, S; Takizawa, Y; Satake, R; Nitta, E; Komai, K; Endo, K; Higuchi, S; Oyake, T; Yoshimura, T; Suenaga, A; Uyama, E; Saito, T; Konagaya, M; Sunohara, N; Namba, R; Takada, H; Honke, K; Nishina, M; Tanaka, H; Shinagawa, M; Tanaka, K; Matsushima, A; Tsuji, S; Takamori, M
      Homozygosity and linkage disequilibrium mapping of autosomal recessive distal myopathy (Nonaka distal myopathy)

      JOURNAL OF HUMAN GENETICS
    4. Higuchi, S; Liu, Y; Yuasa, T; Maeda, A; Motohashi, Y
      Diurnal variations in alpha power density and subjective sleepiness while performing repeated vigilance tasks

      CLINICAL NEUROPHYSIOLOGY
    5. Yamaguchi, J; Hachiuma, K; Kimura, Y; Ogawa, N; Higuchi, S
      Highly sensitive determination of TS-962 (HL-004), a novel acyl-CoA : cholesterol acyltransferase inhibitor, in rat and rabbit plasma by liquid chromatography and atmospheric pressure chemical ionization-tandem mass spectrometry combined with a column-switching technique

      JOURNAL OF CHROMATOGRAPHY B
    6. Akbari, AA; Higuchi, S
      Optimum machining conditions for mirror polishing of aluminum alloy using a robot

      JSME INTERNATIONAL JOURNAL SERIES C-MECHANICAL SYSTEMS MACHINE ELEMENTS AND MANUFACTURING
    7. Ohdo, S; Koyanagi, S; Suyama, H; Higuchi, S; Aramaki, H
      Changing the dosing schedule minimizes the disruptive effects of interferon on clock function

      NATURE MEDICINE
    8. Sunada, Y; Ohi, H; Hase, A; Ohi, H; Hosono, T; Arata, S; Higuchi, S; Matsumura, K; Shimizu, T
      Transgenic mice expressing mutant caveolin-3 show severe myopathy associated with increased nNOS activity

      HUMAN MOLECULAR GENETICS
    9. Ito, S; Ieiri, I; Tanabe, M; Suzuki, A; Higuchi, S; Otsubo, K
      Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects

      PHARMACOGENETICS
    10. Yamaguchi, J; Matsuno, Y; Hachiuma, K; Ogawa, N; Higuchi, S
      A strategy for quantitative bioanalysis of non-polar neutral compounds by liquid chromatography/electrospray ionization tandem mass spectrometry: determination of TS-962, a novel acyl-CoA : cholesterol acyltransferase inhibitor, in rabbit aorta and liver tissues

      RAPID COMMUNICATIONS IN MASS SPECTROMETRY
    11. Hayashi, N; Aso, H; Higashida, M; Kinoshita, H; Ohdo, S; Yukawa, E; Higuchi, S
      Estimation of rhG-CSF absorption kinetics after subcutaneous administration using a modified Wagner-Nelson method with a nonlinear elimination model

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    12. Endo, H; Yoshida, H; Hasegawa, M; Ohmi, N; Horiuchi, N; Hamada, Y; Higuchi, S
      Stereoselectivity and species difference in plasma protein binding of KE-298 and its metabolites

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    13. Nakajima, Y; Hoshi, F; Higuchi, S; Kawamura, S
      Determination of canine beta 2-microgloblin in plasma and urine by enzyme-linked immunosorbent assay

      JOURNAL OF VETERINARY MEDICAL SCIENCE
    14. Nagahara, Y; Matsuoka, Y; Saito, K; Ikekita, M; Higuchi, S; Shinomiya, T
      Coordinate involvement of cell cycle arrest and apoptosis strengthen the effect of FTY720

      JAPANESE JOURNAL OF CANCER RESEARCH
    15. Maeda, A; Nakamura, K; Higuchi, S; Yuasa, T; Motohashi, Y
      Postural sway during cane use by patients with stroke

      AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
    16. Matsui, T; Morikawa, Y; Tojo, M; Okamura, N; Maruyama, M; Hirai, H; Chiba, H; Matsushita, S; Higuchi, S; Arai, H; Sasaki, H
      Cathepsin D polymorphism not associated with Alzheimer's disease in Japanese

      ANNALS OF NEUROLOGY
    17. Kimura, M; Matsushita, S; Arai, H; Takeda, A; Higuchi, S
      No evidence of association between a dopamine transporter gene polymorphism (1215A/G) and Parkinson's disease

      ANNALS OF NEUROLOGY
    18. Yukawa, E; Suematu, F; Yukawa, M; Minemoto, M; Ohdo, S; Higuchi, S; Goto, Y; Aoyama, T
      Population pharmacokinetics of digoxin in Japanese patients - A 2-compartment pharmacokinetic model

      CLINICAL PHARMACOKINETICS
    19. Endo, H; Yoshida, H; Ohmi, N; Higuchi, S
      Effects of lansoprazole, clarithromycin and pH gradient on uptake of [C-14]amoxycillin into rat gastric tissue

      Journal of antimicrobial chemotherapy
    20. Yukawa, E; Nonaka, T; Yukawa, M; Ohdo, S; Higuchi, S; Kuroda, T; Goto, Y
      Pharmacoepidemiologic investigation of a clonazepam-carbamazepine interaction by mixed effect modeling using routine clinical pharmacokinetic data inJapanese patients

      JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
    21. Yukawa, E; Satou, M; Nonaka, T; Yukawa, M; Ohdo, S; Higuchi, S; Kuroda, T; Goto, Y
      Influence of age and comedication on steady-state clonazepam serum level-dose ratios in Japanese epileptic patients

      JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
    22. Matsushita, S; Arai, H; Yuzuriha, T; Kato, M; Matsui, T; Urakami, K; Higuchi, S
      No association between DLST gene and Alzheimer's disease or Wernicke-Korsakoff syndrome

      NEUROBIOLOGY OF AGING
    23. Matsushita, S; Muramatsu, T; Murayama, M; Nakane, J; Higuchi, S
      Alcoholism, ALDH2*2 allele and the A1 allele of the dopamine D2 receptor gene: an association study

      PSYCHIATRY RESEARCH
    24. Hadama, A; Ieiri, I; Morita, T; Kimura, M; Urae, A; Irie, S; Kaneda, T; Mamiya, K; Tashiro, N; Higuchi, S; Otsubo, K
      P-hydroxylation of phenobarbital: Relationship to (s)-mephenytoin hydroxylation (CYP2C19) polymorphism

      THERAPEUTIC DRUG MONITORING
    25. Mamiya, K; Kojima, K; Yukawa, E; Higuchi, S; Ieiri, I; Ninomiya, H; Tashiro, N
      Phenytoin intoxication induced by fluvoxamine

      THERAPEUTIC DRUG MONITORING
    26. Matsushita, S; Yoshino, A; Murayama, M; Kimura, M; Muramatsu, T; Higuchi, S
      Association study of serotonin transporter gene regulatory region polymorphism and alcoholism

      AMERICAN JOURNAL OF MEDICAL GENETICS
    27. Harada, S; Agarwal, DP; Nomura, F; Higuchi, S
      Metabolic and ethnic determinants of alcohol drinking habits and vulnerability to alcohol-related disorder

      ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
    28. Eriksson, CJP; Fukunaga, T; Sarkola, T; Chen, WJ; Chen, CC; Ju, JM; Cheng, ATA; Yamamoto, H; Kohlenberg-Muller, K; Kimura, M; Murayama, M; Matsushita, S; Kashima, H; Higuchi, S; Carr, L; Viljoen, D; Brooke, L; Stewart, T; Foroud, T; Su, J; Li, TK; Whitfield, JB
      Functional relevance of human ADH polymorphism

      ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
    29. Suwaki, H; Kalant, H; Higuchi, S; Crabbe, JC; Ohkuma, S; Katsura, M; Yoshimura, M; Stewart, RC; Li, TK; Weiss, F
      Recent research on alcohol tolerance and dependence

      ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
    30. Yokoyama, A; Muramatsu, T; Omori, T; Yokoyama, T; Matsushita, S; Higuchi, S; Maruyama, K; Ishii, H
      Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics

      CARCINOGENESIS
    31. Yamaguchi, JI; Ohmichi, M; Hasegawa, M; Yoshida, H; Ogawa, N; Higuchi, S
      Identification of rat urinary and biliary metabolites of esonarimod, a novel antirheumatic drug, using liquid chromatography/electrospray ionization tandem mass spectrometry with postcolumn addition of 2-(2-methoxyethoxy)ethanol, a signal-enhancing modifier

      DRUG METABOLISM AND DISPOSITION
    32. Matsunaga, T; Tanaka, H; Higuchi, S; Shibayama, K; Kishi, N; Watanabe, K; Yamamoto, I
      Oxidation mechanism of 7-hydroxy-Delta(8)-tetrahydrocannabinol and 8-hydroxy-Delta(9)-tetrahydrocannabinol to the corresponding ketones by CYP3A11

      DRUG METABOLISM AND DISPOSITION
    33. Endo, H; Yoshida, H; Ohmi, N; Higuchi, S
      Effects of lansoprazole and amoxicillin on uptake of [C-14]clarithromycin into gastric tissue in rats

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    34. Wang, DS; Ohdo, S; Koyanagi, S; Takane, H; Aramaki, H; Yukawa, E; Higuchi, S
      Effect of dosing schedule on pharmacokinetics of alpha interferon and anti-alpha interferon neutralizing antibody in mice

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    35. Oikawa, K; Kamimura, H; Watanabe, T; Miyamoto, I; Higuchi, S
      Pharmacokinetic properties of a novel tissue-type plasminogen activator pamiteplase after single intravenous administration to rats, dogs, and monkeys

      THROMBOSIS RESEARCH
    36. Matsui, T; Arai, H; Yuzuriha, T; Yao, H; Miura, M; Hashimoto, S; Higuchi, S; Matsushita, S; Morikawa, M; Kato, A; Sasaki, H
      Elevated plasma homocysteine levels and risk of silent brain infarction inelderly people

      STROKE
    37. Kondo, S; Amaya, K; Higuchi, S; Saito, T; Asada, H; Ishikane, M
      Fundamental optical absorption of Cs4PbCl6

      SOLID STATE COMMUNICATIONS
    38. Suematsu, F; Yukawa, E; Yukawa, M; Minemoto, M; Ohdo, S; Higuchi, S; Goto, Y
      Population-based investigation of relative clearance of digoxin in Japanese neonates and infants by multiple-trough screen analysis

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    39. Chino, Y; Minagawa, T; Kohno, Y; Toda, Y; Murakami, S; Higuchi, S
      Uptake by vascular smooth muscle cells plays an important role in targeting of lipid microspheres incorporating prostaglandin E-1 into a thickened intima

      LIFE SCIENCES
    40. Takane, H; Ohdo, S; Yamada, T; Koyanagi, S; Yukawa, E; Higuchi, S
      Relationship between diurnal rhythm of cell cycle and interferon receptor expression in implanted-tumor cells

      LIFE SCIENCES
    41. Viyoch, J; Ohdo, S; Yukawa, E; Higuchi, S
      Dosing time-dependent tolerance of catalepsy by repetitive administration of haloperidol in mice

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    42. Tanabe, M; Ieiri, I; Nagata, N; Inoue, K; Ito, S; Kanamori, Y; Takahashi, M; Kurata, Y; Kigawa, J; Higuchi, S; Terakawa, N; Otsubo, K
      Expression of P-glycoprotein in human placenta: Relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    43. Nakazawa, A; Usuda, N; Matsui, T; Hanai, T; Matsushita, S; Arai, H; Sasaki, H; Higuchi, S
      Localization of calcineurin in the mature and developing retina

      JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
    44. Kamada, O; Higuchi, S
      Magnetic field sensors using Ce : YIG single crystals as a faraday element

      IEEE TRANSACTIONS ON MAGNETICS
    45. Higuchi, S; Ueda, K; Yahiro, F; Nakata, Y; Uetsuhara, H; Okada, T; Maeda, M
      Fabrications of cerium-substituted YIG thin films for magnetic field sensor by pulsed-laser deposition

      IEEE TRANSACTIONS ON MAGNETICS
    46. Higuchi, S; Tanimoto, A; Arima, N; Xu, H; Murata, Y; Hamada, T; Makishima, K; Sasaguri, Y
      Effects of histamine and interleukin-4 synthesized in arterial intima on phagocytosis by monocytes/macrophages in relation to atherosclerosis

      FEBS LETTERS
    47. Shintani, M; Ieiri, I; Inoue, K; Mamiya, K; Ninomiya, H; Tashiro, N; Higuchi, S; Otsubo, K
      Genetic polymorphisms and functional characterization of the 5 '-flanking region of the human CYP2C9 gene: In vitro and in vivo studies

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    48. Nishiguchi, N; Matsushita, S; Suzuki, K; Murayama, M; Shirakawa, O; Higuchi, S
      Association between 5HT2A receptor gene promoter region polymorphism and eating disorders in Japanese patients

      BIOLOGICAL PSYCHIATRY
    49. Nakasako, M; Fujisawa, T; Adachi, S; Kudo, T; Higuchi, S
      Large-scale domain movements and hydration structure changes in the active-site cleft of unligated glutamate dehydrogenase from Thermococcus profundus studied by cryogenic X-ray crystal structure analysis and small-angle X-ray scattering

      BIOCHEMISTRY
    50. Okoshi, M; Higuchi, S; Hanabusa, M
      Synthesis of microcrystals from frozen acetone irradiated by a femtosecondlaser

      JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS SHORT NOTES & REVIEW PAPERS
    51. Higuchi, S; Yoshino, A; Matsui, T; Matsushita, S; Satoh, A; Iimura, T; Ishikawa, M; Arai, H; Shirakura, K
      A novel PS1 mutation (W165G) in a Japanese family with early-onset Alzheimer's disease

      ALZHEIMERS REPORTS
    52. Kato, K; Jingu, S; Ogawa, N; Higuchi, S
      Development and validation of a liquid chromatographic-tandem mass spectrometric method for the determination of pibutidine in human urine

      JOURNAL OF CHROMATOGRAPHY B
    53. Loh, EW; Higuchi, S; Matsushita, S; Murray, R; Chen, CK; Ball, D
      Association analysis of the GABA(A) receptor subunit genes cluster on 5q33-34 and alcohol dependence in a Japanese population

      MOLECULAR PSYCHIATRY
    54. Motohashi, Y; Maeda, A; Wakamatsu, H; Higuchi, S; Yuasa, T
      Circadian rhythm abnormalities of wrist activity of institutionalized dependent elderly persons with dementia

      JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
    55. Koch, HG; McClay, J; Loh, EW; Higuchi, S; Zhao, JH; Sham, P; Ball, D; Craig, IW
      Allele association studies with SSR and SNP markers at known physical distances within a 1 Mb region embracing the ALDH2 locus in the Japanese, demonstrates linkage disequilibrium extending up to 400 kb

      HUMAN MOLECULAR GENETICS
    56. Imai, J; Ieiri, I; Mamiya, K; Miyahara, S; Furuumi, H; Nanba, E; Yamane, M; Fukumaki, Y; Ninomiya, H; Tashiro, N; Otsubo, K; Higuchi, S
      Polymorphism of the cytochrome P450 (CYP) 2C9 gene in Japanese epileptic patients: genetic analysis of the CYP2C9 locus

      PHARMACOGENETICS
    57. Ono, G; Terao, H; Higuchi, S; Sugawara, T; Izuoka, A; Mochida, T
      One-dimensional double chain composed of carbamoylmethylthio-substituted TTF-based donor in ion radical salt

      JOURNAL OF MATERIALS CHEMISTRY
    58. Higuchi, S; Matsushita, S; Nakane, J; Arai, H; Matsui, T; Urakami, K; Yuzuriha, T; Takeda, A
      alpha(2)-macroglobulin gene polymorphisms show racial diversity and are not associated with Alzheimer's disease

      NEUROREPORT
    59. Matsunaga, T; Shibayama, K; Higuchi, S; Tanaka, H; Watanabe, K; Yamamoto, I
      Characterization of microsomal alcohol oxygenase catalyzing the oxidation of 7-hydroxy-Delta(8)-tetrahydrocannabinol to 7-oxo-Delta(8)-tetrahydrocannabinol in rat liver

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    60. Hoshi, F; Nagai, D; Nakajima, Y; Higuchi, S; Kawamura, S
      Purification of bovine urinary beta(2)-microglobulin and its biochemical characteristics

      JOURNAL OF VETERINARY MEDICAL SCIENCE
    61. Fukushima, U; Miyashita, K; Okano, S; Higuchi, S; Takase, K; Hagio, M
      Evaluation of intracranial pressure by transcranial Doppler ultrasonography in dogs with intracranial hypertension

      JOURNAL OF VETERINARY MEDICAL SCIENCE
    62. Maeda, A; Yuasa, T; Nakamura, K; Higuchi, S; Motohashi, Y
      Physical performance tests after stroke - Reliability and validity

      AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
    63. Higuchi, S; Liu, Y; Yuasa, T; Maeda, A; Motohashi, Y
      Diurnal variation in the P300 component of human cognitive event-related potential

      CHRONOBIOLOGY INTERNATIONAL
    64. Tajima, M; Higuchi, Y; Miyamoto, N; Higuchi, S; Ito, M; Tsurudome, M; Sudo, A; Ito, Y; Uchida, A
      Ability of osteoclast formation from peripheral monocytes using anti-fusion regulatory protein-1/CD98/4F2 monoclonal antibodies in patients with osteoporosis

      JOURNAL OF ORTHOPAEDIC RESEARCH
    65. Kato, K; Jingu, S; Ogawa, N; Higuchi, S
      Determination of pibutidine metabolites in human plasma by LC-MS/MS

      JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
    66. Morishita, H; Hoshino, Y; Higuchi, S; Kaneko, F; Tashiro, K; Kobayashi, M
      Partial depolarization effect of high-numerical-aperture objectives on polarized microfocus Raman spectra of orthorhombic poly(oxymethylene) single crystal

      JOURNAL OF RAMAN SPECTROSCOPY
    67. Higuchi, S; Ohta, S; Matsushita, S; Matsui, T; Yuzuriha, T; Urakami, K; Arai, H
      NOS3 polymorphism not associated with Alzheimer's disease in Japanese

      ANNALS OF NEUROLOGY
    68. Takanaga, H; Ohnishi, A; Matsuo, H; Murakami, H; Sata, H; Kuroda, K; Urae, A; Higuchi, S; Sawada, Y
      Pharmacokinetic analysis of felodipine-grapefruit juice interaction based on an irreversible enzyme inhibition model

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    69. Higuchi, S
      Loop model with generalized fugacity in three dimensions

      JOURNAL OF PHYSICS A-MATHEMATICAL AND GENERAL
    70. Kimura, M; Matsushita, S; Arai, H; Matsui, T; Yuzuriha, T; Higuchi, S
      No evidence of association between apolipoprotein E gene regulatory regionpolymorphism and Alzheimer's disease in Japanese

      JOURNAL OF NEURAL TRANSMISSION
    71. Yukawa, E; Hokazono, T; Funakoshi, A; Yukawa, M; Ohdo, S; Higuchi, S; Ichimaru, R; Maki, T; Matsunaga, K; Anai, M; Goto, Y
      Epidemiologic investigation of the relative clearance of haloperidol by mixed-effect modeling using routine clinical pharmacokinetic data in Japanesepatients

      JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
    72. Noguchi, K; Watanabe, T; Higuchi, S; Chiba, K
      Determination of YM992, a novel selective serotonin reuptake inhibitor, inrat and dog plasma by high-performance liquid chromatography with fluorescence detection

      BIOMEDICAL CHROMATOGRAPHY
    73. Michel, GH; Murayama, N; Sada, T; Nozaki, M; Saguchi, K; Ohi, H; Fujita, Y; Koike, H; Higuchi, S
      Two N-terminally truncated forms of C-type natriuretic peptide from habu snake venom

      PEPTIDES
    74. Okoshi, M; Higuchi, S; Hanabusa, M
      Deposition of diamond-like carbon films by femtosecond laser ablation using frozen acetone targets

      APPLIED SURFACE SCIENCE
    75. Ieiri, I; Tainaka, H; Morita, T; Hadama, A; Mamiya, K; Hayashibara, M; Ninomiya, H; Ohmori, S; Kitada, M; Tashiro, N; Higuchi, S; Otsubo, K
      Catalytic activity of three variants (Ile, Leu, and Thr) at amino acid residue 359 in human CYP2C9 gene and simultaneous detection using single-strand conformation polymorphism analysis

      THERAPEUTIC DRUG MONITORING
    76. Ninomiya, H; Mamiya, K; Matsuo, S; Ieiri, I; Higuchi, S; Tashiro, N
      Genetic polymorphism of the CYP2C subfamily and excessive serum phenytoin concentration with central nervous system intoxication

      THERAPEUTIC DRUG MONITORING
    77. Okubo, T; Harada, S; Higuchi, S; Matsushita, S
      Genetic polymorphism of the CCK gene in patients with alcohol withdrawal symptoms

      ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
    78. Matsushita, S; Kato, M; Muramatsu, T; Higuchi, S
      Alcohol and aldehyde dehydrogenase genotypes in Korsakoff syndrome

      ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
    79. Makimoto, K; Oda, H; Higuchi, S
      Is heavy alcohol consumption an attributable risk factor for cancer-related deaths among Japanese men?

      ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
    80. Oikawa, K; Watanabe, T; Higuchi, S
      Comparison of drug disposition between wild-type and novel tissue-type plasminogen activator pamiteplase in rats

      DRUG METABOLISM AND DISPOSITION
    81. Matsunaga, T; Kishi, N; Higuchi, S; Watanabe, K; Ohshima, T; Yamamoto, I
      CYP3A4 is a major isoform responsible for oxidation of 7-hydroxy-Delta(8)-tetrahydrocannabinol to 7-oxo-Delta(8)-tetrahydrocannabinol in human liver microsomes

      DRUG METABOLISM AND DISPOSITION
    82. Oikawa, K; Watanabe, T; Higuchi, S
      Comparison of receptor-mediated endocytosis kinetics between wild-type t-PA and recombinant pamiteplase in isolated rat hepatocytes and liver cell plasma membranes

      XENOBIOTICA
    83. Noguchi, K; Mera, A; Watanabe, T; Higuchi, S; Chiba, K
      Identification of cytochrome P450 isoform involved in the metabolism of YM992, a novel selective serotonin re-uptake inhibitor, in human liver microsomes

      XENOBIOTICA
    84. Miyahara, T; Gomyo, S; Ueda, Y; Ohyama, Y; Sigeno, C; Kozakai, A; Takamura, T; Yamazaki, R; Higuchi, S; Yamamoto, M; Sakuma, T; Nemoto, N
      Metabolism of 26,27-hexafluoro-1 alpha,25-dihydroxyvitamin D-3 and 26,27-hexafluoro-1 alpha,23(S)25-trihydroxyvitamin D-3 in ROS17/2.8 cells transfected with a plasmid expressing CYP24

      XENOBIOTICA
    85. Oikawa, K; Watanabe, T; Miyamoto, I; Higuchi, S
      Determination, pharmacokinetics and protein binding of a novel tissue-typeplasminogen activator, pamiteplase in human plasma

      XENOBIOTICA
    86. Matsui, T; Usuda, N; Arai, H; Nakazawa, A; Matsushita, S; Higuchi, S; Sasaki, H
      Rapid nonradioactive in-situ hybridization for mRNA detection of calcineurin in rat brain using PCR DNA probe

      ACTA HISTOCHEMICA ET CYTOCHEMICA
    87. Shimamoto, J; Ieiri, I; Urae, A; Kimura, M; Irie, S; Kubota, T; Chiba, K; Ishizaki, T; Otsubo, K; Higuchi, S
      Lack of differences in diclofenac (a substrate for CYP2C9) pharmacokinetics in healthy volunteers with respect to the single CYP2C9*3 allele

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    88. Mamiya, K; Hadama, A; Yukawa, E; Ieiri, I; Otsubo, K; Ninomiya, H; Tashiro, N; Higuchi, S
      CYP2C19 polymorphism effect on phenobarbitone - Pharmacokineties in Japanese patients with epilepsy: analysis by population pharmacokinetics

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    89. Kawashima, T; Amano, N; Koike, H; Makino, S; Higuchi, S; Kawashima-Ohya, Y; Watanabe, K; Yamazaki, M; Kanehori, K; Kawamoto, T; Nunoshiba, T; Yamamoto, Y; Aramaki, H; Makino, K; Suzuki, M
      Archaeal adaptation to higher temperatures revealed by genomic sequence ofThermoplasma volcanium

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    90. To, H; Kikuchi, A; Tsuruoka, S; Sugimoto, K; Fujimura, A; Higuchi, S; Kayama, F; Hara, K; Matsuno, K; Kobayashi, E
      Time-dependent nephrotoxicity associated with daily administration of cisplatin in mice

      JOURNAL OF PHARMACY AND PHARMACOLOGY
    91. Kobayashi, M; To, H; Yuzawa, M; Hakamata, Y; Higuchi, S; Tokue, A; Fujimura, A; Kobayashi, E
      Effects of dosing time and schedule on cisplatin-induced nephrotoxicity inrats

      JOURNAL OF PHARMACY AND PHARMACOLOGY
    92. Ohdo, S; Wang, DS; Koyanagi, S; Takane, H; Inoue, K; Aramaki, H; Yukawa, E; Higuchi, S
      Basis for dosing time-dependent changes in the antiviral activity of interferon-alpha in mice

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    93. Takane, H; Ohdo, S; Yamada, T; Yukawa, E; Higuchi, S
      Chronopharmacology of antitumor effect induced by interferon-beta in tumor-bearing mice

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    94. Matsushima, H; Watanabe, T; Higuchi, S
      Effect of alpha(1)-acid glycoprotein on the pharmacokinetics of tamsulosinin rats treated with turpentine oil

      JOURNAL OF PHARMACEUTICAL SCIENCES
    95. Wang, KY; Arima, N; Higuchi, S; Shimajiri, S; Tanimoto, A; Murata, Y; Hamada, T; Sasaguri, Y
      Switch of histamine receptor expression from H2 to H1 during differentiation of monocytes into macrophages

      FEBS LETTERS
    96. Higuchi, M; Tashiro, M; Arai, H; Okamura, N; Hara, S; Higuchi, S; Itoh, M; Shin, RW; Trojanowski, JQ; Sasaki, H
      Glucose hypometabolism and neuropathological correlates in brains of dementia with Lewy bodies

      EXPERIMENTAL NEUROLOGY
    97. Murayama, N; Michel, GH; Yanoshita, R; Samejima, Y; Saguchi, K; Ohi, H; Fujita, Y; Higuchi, S
      cDNA cloning of bradykinin-potentiating peptides-C-type natriuretic peptide precursor, and characterization of the novel peptide Leu3-blomhotin from the venom of Agkistrodon blomhoffi

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    98. Furuya, A; Kato, N; Jingu, S; Akimoto, M; Higuchi, S; Suwa, T; Ogata, H
      Population pharmacokinetics and pharmacodynamics of TS-943 for selective nonpeptide platelet glycoprotein IIb/IIIa receptor antagonist in normal healthy subjects

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    99. Takanaga, H; Ohnishi, A; Murakami, H; Matsuo, H; Higuchi, S; Urae, A; Irie, S; Furuie, H; Matsukuma, K; Kimura, M; Kawano, K; Orii, Y; Tanaka, T; Sawada, Y
      Relationship between time after intake of grapefruit juice and the effect on pharmacokinetics and pharmacodynamics of nisoldipine in healthy subjects

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    100. Higuchi, Y; Ito, M; Tajima, M; Higuchi, S; Miyamoto, N; Nishio, M; Kawano, M; Kusagawa, S; Tsurudome, M; Sudo, A; Katou, K; Uchida, A; Ito, Y
      Gene expression during osteoclast-like cell formation induced by antifusion regulatory protein-1/CD98/4F2 monoclonal antibodies (MAbs): c-src is selectively induced by Anti-FRP-1 MAb

      BONE


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/10/20 alle ore 03:10:51