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    1. Summers, YJ; Heyworth, CM; de Wynter, EA; Chang, J; Testa, NG
      Cord blood G(0) CD34(+) cells have a thousand-fold higher capacity for generating progenitors in vitro than G(1) CD34(+) cells

      STEM CELLS
    2. de Wynter, EA; Heyworth, CM; Mukaida, N; Matsushima, K; Testa, NG
      NOD/SCID repopulating cells but not LTC-IC are enriched in human CD34(+) cells expressing the CCR1 chemokine receptor

      LEUKEMIA
    3. Henschler, R; Appel, KE; Heyworth, CM; Glatt, H
      Proliferation and differentiation of murine haemopoietic progenitor cells in stroma-free culture in the presence of metabolites of chlorinated pesticides

      TOXICOLOGY IN VITRO
    4. de Wynter, EA; Heyworth, CM; Mukaida, N; Jaworska, E; Weffort-Santos, A; Matushima, K; Testa, NG
      CCR1 chemokine receptor expression isolates erythroid from granulocyte-macrophage progenitors

      JOURNAL OF LEUKOCYTE BIOLOGY
    5. Baird, JW; Ryan, KM; Hayes, I; Hampson, L; Heyworth, CM; Clark, A; Wootton, M; Ansell, JD; Menzel, U; Hole, N; Graham, GJ
      Differentiating embryonal stem cells are a rich source of haemopoietic gene products and suggest erythroid preconditioning of primitive haemopoietic stem cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    6. Zhu, J; Heyworth, CM; Glasow, A; Huang, QH; Petrie, K; Lanotte, M; Benoit, G; Gallagher, R; Waxman, S; Enver, T; Zelent, A
      Lineage restriction of the RAR alpha gene expression in myeloid differentiation

      BLOOD
    7. Francis, JM; Heyworth, CM; Spooncer, E; Pierce, A; Dexter, TM; Whetton, AD
      Transforming growth factor-beta 1 induces apoptosis independently of p53 and selectively reduces expression of Bcl-2 in multipotent hematopoietic cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    8. McIvor, ZJ; Heyworth, CM; Johnson, BA; Pearson, S; Fiegler, H; Hampson, L; Dexter, TM; Cross, MA
      A transient assay for regulatory gene function in haemopoietic progenitor cells

      BRITISH JOURNAL OF HAEMATOLOGY
    9. Durig, J; Testa, NG; Heyworth, CM
      Distinct biological effects of macrophage inflammatory protein-1 alpha andstroma-derived factor-1 alpha on CD34(+) hemopoietic cells

      STEM CELLS
    10. Durig, J; Testa, NG; Lord, BI; Kasper, C; Chang, J; Telford, N; Dexter, TM; Heyworth, CM
      Characterisation of the differential response of normal and CML haemopoietic progenitor cells to macrophage inflammatory protein-1 alpha

      LEUKEMIA
    11. Johnson, BA; John, VA; Henschler, R; Hampson, IN; Heyworth, CM; Babichuk, CK; Bleackley, RC; Dexter, TM; Cross, MA
      Upstream elements bestow T-cell and haemopoietic progenitor-specific activity on the granzyme B promoter

      GENE
    12. Czaplewski, LG; McKeating, J; Craven, CJ; Higgins, LD; Appay, V; Brown, A; Dudgeon, T; Howard, LA; Meyers, T; Owen, J; Palan, SR; Tan, P; Wilson, G; Woods, NR; Heyworth, CM; Lord, BI; Brotherton, D; Christison, R; Craig, S; Cribbes, S; Edwards, RM; Evans, SJ; Gilbert, R; Morgan, P; Randle, E; Schofield, N; Varley, PG; Fisher, J; Waltho, JP; Hunter, MG
      Identification of amino acid residues critical for aggregation of human CCchemokines macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta, and RANTES - Characterization of active disaggregated chemokine variants

      JOURNAL OF BIOLOGICAL CHEMISTRY
    13. Evans, CA; Pierce, A; Winter, SA; Spooncer, E; Heyworth, CM; Whetton, AD
      Activation of granulocyte-macrophage colony-stimulating factor and interleukin-3 receptor subunits in a multipotential hematopoietic progenitor cell line leads to differential effects on development

      BLOOD
    14. Scheller, M; Foerster, J; Heyworth, CM; Waring, JF; Lohler, J; Gilmore, GL; Shadduck, RK; Dexter, TM; Horak, I
      Altered development and cytokine responses of myeloid progenitors in the absence of transcription factor, interferon consensus sequence binding protein

      BLOOD
    15. DEWYNTER EA; DURIG J; CROSS MA; HEYWORTH CM; TESTA NG
      DIFFERENTIAL RESPONSE OF CD34(-BLOOD AND BONE-MARROW TO MIP-1-ALPHA AND THE EXPRESSION OF MIP-1-ALPHA RECEPTORS ON THESE IMMATURE CELLS() CELLS ISOLATED FROM CORD)

      Stem cells
    16. WARK G; HEYWORTH CM; SPOONCER E; CZAPLEWSKI L; FRANCIS JM; DEXTER TM; WHETTON AD
      ABL PROTEIN-KINASE ABROGATES THE RESPONSE OF MULTIPOTENT HEMATOPOIETIC-CELLS TO THE GROWTH INHIBITOR MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA

      Oncogene
    17. DURIG J; TESTA NG; LORD BI; KASPER C; CHANG J; TELFORD N; DEXTER TM; HEYWORTH CM
      CHARACTERIZATION OF THE DIFFERENTIAL RESPONSE OF NORMAL AND CML HEMATOPOIETIC PROGENITOR CELLS TO MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA

      Annals of oncology
    18. PEARSON MA; OFARRELL AM; DEXTER TM; WHETTON AD; OWENLYNCH PJ; HEYWORTH CM
      INVESTIGATION OF THE MOLECULAR MECHANISMS UNDERLYING GROWTH-FACTOR SYNERGY - THE ROLE OF ERK-2 ACTIVATION IN SYNERGY

      Growth factors
    19. DURIG J; TESTA NG; HEYWORTH CM
      DISTINCT BIOLOGICAL EFFECTS OF MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA AND STROMA DERIVED FACTOR-1-ALPHA ON CD34+ HEMATOPOIETIC PROGENITOR CELLS

      Experimental hematology
    20. BUREL S; HEYWORTH CM; GEORGE E; DEXTER TM
      THE FACTOR-DEPENDENT CELL-LINE PATERSON MIX AS MODEL SYSTEM FOR ROUTINE ASSESSMENT OF MYELOTOXICITY IN-VITRO

      Experimental hematology
    21. PIERCE A; WHETTON AD; OWENLYNCH PJ; TAVERNIER J; SPOONCER E; DEXTER TM; HEYWORTH CM
      ECTOPIC INTERLEUKIN-5 RECEPTOR EXPRESSION PROMOTES PROLIFERATION WITHOUT DEVELOPMENT IN A MULTIPOTENT HEMATOPOIETIC-CELL LINE

      Journal of Cell Science
    22. PIERCE A; HEYWORTH CM; NICHOLLS SE; SPOONCER E; DEXTER TM; LORD JM; OWENLYNCH PJ; WARK G; WHETTON AD
      AN ACTIVATED PROTEIN-KINASE-C-ALPHA GIVES A DIFFERENTIATION SIGNAL FOR HEMATOPOIETIC PROGENITOR CELLS AND MIMICS MACROPHAGE-COLONY-STIMULATING FACTOR-STIMULATED SIGNALING EVENTS

      The Journal of cell biology
    23. DURIG J; CHANG J; KASPER C; TELFORD N; DEWYNTER EA; TESTA NG; CROSS MA; CHOPRA R; HEYWORTH CM; LORD BI; DEXTER TM
      DIFFERENTIAL RESPONSIVENESS OF CML AND NORMAL HEMATOPOIETIC PROGENITOR CELLS TO MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA (MIP-1-ALPHA)

      British Journal of Haematology
    24. DURIG J; DEWYNTER EA; KASPER C; CROSS MA; CHANG J; TESTA NG; HEYWORTH CM
      EXPRESSION OF MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA RECEPTORS IN HUMAN CD34(-CELLS AND THEIR MODULATION BY TUMOR-NECROSIS-FACTOR-ALPHA AND INTERFERON-GAMMA() HEMATOPOIETIC)

      Blood
    25. ENVER T; HEYWORTH CM; DEXTER TM
      DO STEM-CELLS PLAY DICE

      Blood
    26. DEWYNTER EA; HEYWORTH CM; TESTA NG
      STIMULATORY AND INHIBITORY EFFECTS OF MIP-1-ALPHA ON PRIMITIVE HEMATOPOIETIC-CELLS

      Experimental hematology
    27. DURIG J; DEWYNTER EA; KASPER C; CHANG J; DEXTER TM; CROSS M; HEYWORTH CM; TESTA NG
      DIFFERENTIAL MIP-1-ALPHA-RESPONSIVENESS IN CML AND NORMAL HEMATOPOIETIC PROGENITOR CELLS

      Experimental hematology
    28. EVANS CA; PIERCE A; WINTER SA; HEYWORTH CM; SPOONCER E; WHETTON AD
      ANALYSIS OF HUMAN GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR AND INTERLEUKIN-3 RECEPTOR FUNCTION IN A MULTIPOTENT MURINE HEMATOPOIETIC-CELL LINE

      Experimental hematology
    29. ZELENT A; ZHU J; LANOTTE M; GALLAGHER R; WAXMAN S; HEYWORTH CM; ENVER T
      DIFFERENTIAL EXPRESSION OF RETINOID RECEPTORS DURING MULTILINEAGE DIFFERENTIATION OF HEMATOPOIETIC PROGENITOR CELLS-ROLE OF THE RAR-ALPHA-2ISOFORM IN NORMAL GRANULOPOIESIS AND LEUKEMIA

      Blood
    30. HAMPSON IN; HAMPSON L; PINKOSKI M; CROSS M; HEYWORTH CM; BLEACKLEY RC; ATKINSON E; DEXTER TM
      IDENTIFICATION OF A SERPIN SPECIFICALLY EXPRESSED IN MULTIPOTENT AND BIPOTENT HEMATOPOIETIC PROGENITOR CELLS AND IN ACTIVATED T-CELLS

      Blood
    31. HEYWORTH CM; DEXTER TM; CROSS MA; ALLEN TD; TESTA NG
      MEGAKARYOCYTIC DEVELOPMENT OF A MULTIPOTENT STEM-CELL LINE, FDCP-MIX

      Experimental hematology
    32. WARK G; PIERCE A; LORD JM; HEYWORTH CM; SPOONCER E; DEXTER TM; WHETTON AD
      RETROVIRAL INFECTION OF GRANULOCYTE-MACROPHAGE PROGENITOR CELLS WITH CONSTITUTIVELY ACTIVE PROTEIN-KINASE C-ALPHA PROMOTES MACROPHAGE DEVELOPMENT

      Experimental hematology
    33. HENSCHLER R; GLATT HR; HEYWORTH CM
      HYDROQUINONE STIMULATES GRANULOCYTE-MACROPHAGE PROGENITOR CELLS IN-VITRO AND IN-VIVO

      Environmental health perspectives
    34. GILLEECE MH; HEYWORTH CM; TESTA NG; DEXTER TM
      EFFECTS OF INTERLEUKINS ON THE PROLIFERATION AND SURVIVAL OF CHRONIC LYMPHOCYTIC-LEUKEMIA CELLS

      Journal of Clinical Pathology
    35. EVANS CA; WINTER SA; HEYWORTH CM; SPOONCER E; WHELTON AD
      ANALYSIS OF HIL-3 AND HGM-CSF RECEPTOR FUNCTION BY TRANSFECTION INTO A MULTIPOTENTIAL STEM-CELL LINE

      Blood
    36. MURRELL AM; BOCKAMP EO; GOTTGENS B; CHAN YS; CROSS MA; HEYWORTH CM; GREEN AR
      DISCORDANT REGULATION OF SCL TAL-1 MESSENGER-RNA AND PROTEIN DURING ERYTHROID-DIFFERENTIATION/

      Oncogene
    37. HEYWORTH CM; PEARSON MA; DEXTER TM; WARK G; OWENLYNCH PJ; WHETTON AD
      MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA MEDIATED GROWTH-INHIBITION INA HEMATOPOIETIC STEM-CELL LINE IS ASSOCIATED WITH INOSITOL 1,4,5-TRISPHOSPHATE GENERATION

      Growth factors
    38. PEARSON M; OWEN PJ; WHETTON AD; DEXTER TM; HEYWORTH CM
      INVESTIGATION OF THE MOLECULAR MECHANISMS BY WHICH SCF SYNERGISTICALLY PROMOTES THE EFFECTS OF CYTOKINES ON FDCP-MIX A4 CELLS

      Experimental hematology
    39. WARK G; WHETTON AD; SPOONCER E; HEYWORTH CM; DEXTER TM
      MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA PROTECTS A HEMATOPOIETIC MULTIPOTENT STEM-CELL LINE FROM THE CYTOTOXIC EFFECTS OF CYCLE-SPECIFIC AGENTS - MODULATION BY ACTIVATION OF V-ABL PROTEIN-TYROSINE KINASE

      Experimental hematology
    40. NICHOLLS SE; HEYWORTH CM; DEXTER TM; LORD JM; JOHNSON GD; WHETTON AD
      IL-4 PROMOTES MACROPHAGE DEVELOPMENT BY RAPIDLY STIMULATING LINEAGE RESTRICTION OF BIPOTENT GRANULOCYTE-MACROPHAGE COLONY-FORMING CELLS

      The Journal of immunology
    41. HEYWORTH CM; ALAULDIN M; CROSS MA; FAIRBAIRN LJ; DEXTER TM; WHETTON AD
      ERYTHROID DEVELOPMENT OF THE FDCP-MIX A4 MULTIPOTENT CELL-LINE IS GOVERNED BY THE RELATIVE CONCENTRATIONS OF ERYTHROPOIETIN AND INTERLEUKIN-3

      British Journal of Haematology
    42. HUNTER MG; BAWDEN L; BROTHERTON D; CRAIG S; CRIBBES S; CZAPLEWSKI LG; DEXTER TM; DRUMMOND AH; GEARING AH; HEYWORTH CM; LORD BI; MCCOURT M; VARLEY PG; WOOD LM; EDWARDS RM; LEWIS PJ
      BB-10010 - AN ACTIVE VARIANT OF HUMAN MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA WITH IMPROVED PHARMACEUTICAL PROPERTIES

      Blood
    43. CROSS MA; HEYWORTH CM; MURRELL AM; BOCKAMP EO; DEXTER TM; GREEN AR
      EXPRESSION OF LINEAGE RESTRICTED TRANSCRIPTION FACTORS PRECEDES LINEAGE-SPECIFIC DIFFERENTIATION IN A MULTIPOTENT HEMATOPOIETIC PROGENITOR-CELL LINE

      Oncogene
    44. DEXTER TM; HEYWORTH CM
      GROWTH-FACTORS AND THE MOLECULAR CONTROL OF HEMATOPOIESIS

      European journal of clinical microbiology & infectious diseases
    45. WHETTON AD; HEYWORTH CM; LORD JL; DEXTER TM; NICHOLLS S; OWENLYNCH PJ
      CYTOKINE-STIMULATED PROTEIN-KINASE-C-ALPHA TRANSLOCATION TO THE NUCLEUS IS ASSOCIATED WITH COMMITMENT OF BIPOTENTIAL GRANULOCYTE-MACROPHAGECOLONY-FORMING CELLS TO MACROPHAGE DEVELOPMENT

      Experimental hematology
    46. HEYWORTH CM; DEXTER TM; NICHOLLS SE; WHETTON AD
      COMBINATIONS OF COLONY-STIMULATING FACTORS PROMOTE ENHANCED PROLIFERATIVE POTENTIAL IN ENRICHED GRANULOCYTE-MACROPHAGE COLONY-FORMING CELLS

      Experimental hematology
    47. WHETTON AD; HEYWORTH CM; NICHOLLS SE; EVANS CA; LORD JM; DEXTER TM; OWENLYNCH PJ
      CYTOKINE-MEDIATED PROTEIN-KINASE-C ACTIVATION IS A SIGNAL FOR LINEAGEDETERMINATION IN BIPOTENTIAL GRANULOCYTE-MACROPHAGE COLONY-FORMING CELLS

      The Journal of cell biology
    48. LORD BI; HEYWORTH CM; WOOLFORD LB
      MACROPHAGE INFLAMMATORY PROTEIN - ITS CHARACTERISTICS, BIOLOGICAL PROPERTIES AND ROLE IN THE REGULATION OF HEMATOPOIESIS

      International journal of hematology
    49. WHETTON AD; NICHOLLS S; OWENLYNCH J; HEYWORTH CM
      LINEAGE DETERMINATION IN BIPOTENTIAL GRANULOCYTE-MACROPHAGE COLONY-FORMING CELLS IS REGULATED BY PROTEIN-KINASE-C

      Experimental hematology
    50. GILLEECE MH; HEYWORTH CM; TESTA NG; DEXTER TM
      INTERLEUKIN-4 RECEPTOR EXPRESSION IN CHRONIC LYMPHOCYTIC-LEUKEMIA

      Experimental hematology


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Documento generato il 16/01/21 alle ore 23:30:38