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La ricerca find articoli where authors phrase all words ' HRUBY VJ' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 267 riferimenti
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    1. Cowell, SM; Balse-Srinivasan, PM; Ahn, JM; Hruby, VJ
      Design and synthesis of peptide antagonists and inverse agonists for G protein-coupled receptors

      G PROTEIN PATHWAYS, PT A, RECEPTORS
    2. Hruby, VJ; Agnes, RS; Cai, CZ
      Design of peptide agonists

      G PROTEIN PATHWAYS, PT A, RECEPTORS
    3. Hruby, VJ; Qiu, W; Okayama, T; Soloshonok, VA
      Design of nonpeptides from peptide ligands for peptide receptors

      G PROTEIN PATHWAYS, PT A, RECEPTORS
    4. Soloshonok, VA; Tang, XJ; Hruby, VJ; Van Meervelt, L
      Asymmetric synthesis of alpha,beta-dialkyl-alpha-phenylalanines via directalkylation of a chiral alanine derivative with racemic alpha-alkylbenzyl bromides. A case of high enantiomer differentiation at room temperature

      ORGANIC LETTERS
    5. Hruby, VJ
      Vincent duVigneaud 1901-1978: a personal tribute

      JOURNAL OF PEPTIDE RESEARCH
    6. Ahn, JM; Medeiros, M; Trivedi, D; Hruby, VJ
      Development of potent glucagon antagonists: structure-activity relationship study of glycine at position 4

      JOURNAL OF PEPTIDE RESEARCH
    7. Liao, S; Shenderovich, M; Kover, KE; Zhang, Z; Hosohata, K; Davis, P; Porreca, F; Yamamura, HI; Hruby, VJ
      Synthesis, biology, NMR and conformation studies of the topographically constrained delta-opioid selective peptide analogs of [beta-iPrPhe(3)]deltorphin I

      JOURNAL OF PEPTIDE RESEARCH
    8. Grieco, P; Gitu, PM; Hruby, VJ
      Preparation of 'side-chain-to-side-chain' cyclic peptides by Allyl and Alloc strategy: potential for library synthesis

      JOURNAL OF PEPTIDE RESEARCH
    9. Wang, ZJ; Gardell, LR; Ossipov, MH; Vanderah, TW; Brennan, MB; Hochgeschwender, U; Hruby, VJ; Malan, TP; Lai, J; Porreca, F
      Pronociceptive actions of dynorphin maintain chronic neuropathic pain

      JOURNAL OF NEUROSCIENCE
    10. Wang, W; Xiong, CY; Yang, JQ; Hruby, VJ
      Practical, asymmetric synthesis of aromatic-substituted bulky and hydrophobic tryptophan derivatives

      TETRAHEDRON LETTERS
    11. Han, GX; Lewis, A; Hruby, VJ
      Synthesis of (2S,3S)-beta-methyltryptophan

      TETRAHEDRON LETTERS
    12. Han, GX; Hruby, VJ
      A study of conjugate addition to a gamma delta-dioxolanyl-alpha,beta-unsaturated ester

      TETRAHEDRON LETTERS
    13. Qiu, W; Gu, XY; Soloshonok, VA; Carducci, MD; Hruby, VJ
      Stereoselective synthesis of conformationally constrained reverse turn dipeptide mimetics

      TETRAHEDRON LETTERS
    14. Wang, W; Xiong, CY; Hruby, VJ
      An efficient approach to asymmetric synthesis of dipeptide beta-turn mimetics: indolizidinone amino acids

      TETRAHEDRON LETTERS
    15. Hruby, VJ; Soloshonok, VA
      Asymmetric synthesis of novel sterically constrained amino acids - Preface

      TETRAHEDRON
    16. Soloshonok, VA; Tang, XJ; Hruby, VJ
      Large-scale asymmetric synthesis of novel sterically constrained 2 ',6 '-dimethyl- and alpha,2 ',6 '-trimethyltyrosine and -phenylalanine derivativesvia alkylation of chiral equivalents of nucleophilic glycine and alanine

      TETRAHEDRON
    17. Lipkowski, AW; Misicka, A; Hosohata, K; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ
      Biological properties of Phe(o)-opioid peptide analogues

      LIFE SCIENCES
    18. Hosohata, Y; Varga, EV; Stropova, D; Li, XP; Knapp, RJ; Hruby, VJ; Rice, KC; Nagase, H; Roeske, WR; Yamamura, HI
      Mutation W284L of the human delta opioid receptor reveals agonist specificreceptor conformations for G protein activation

      LIFE SCIENCES
    19. Mitchell, SA; Pratt, MR; Hruby, VJ; Polt, R
      Solid-phase synthesis of O-linked glycopeptide analogues of enkephalin

      JOURNAL OF ORGANIC CHEMISTRY
    20. Cai, CZ; Soloshonok, VA; Hruby, VJ
      Michael addition reactions between chiral Ni(II) complex of glycine and 3-(trans-enoyl)oxazolidin-2-ones. A case of electron donor-acceptor attractive interaction-controlled face diastereoselectivity

      JOURNAL OF ORGANIC CHEMISTRY
    21. Tamaki, M; Han, GX; Hruby, VJ
      Practical and efficient synthesis of orthogonally protected constrained 4-guanidinoprolines

      JOURNAL OF ORGANIC CHEMISTRY
    22. Tamaki, M; Han, GX; Hruby, VJ
      Synthesis of 4-cis-phenyl-L-proline via hydrogenolysis

      JOURNAL OF ORGANIC CHEMISTRY
    23. Ahn, JM; Medeiros, M; Trivedi, D; Hruby, VJ
      Development of potent truncated glucagon antagonists

      JOURNAL OF MEDICINAL CHEMISTRY
    24. Ahn, JM; Gitu, PM; Medeiros, M; Swift, JR; Trivedi, D; Hruby, VJ
      A new approach to search for the bioactive conformation of glucagon: Positional cyclization scanning

      JOURNAL OF MEDICINAL CHEMISTRY
    25. Hruby, VJ
      Design in topographical space of peptide and peptidomimetic ligands that affect behavior. A chemist's glimpse at the mind-body problem

      ACCOUNTS OF CHEMICAL RESEARCH
    26. Soloshonok, VA; Cai, CZ; Hruby, VJ
      (S)- or (R)-3-(E-enoyl)-4-phenyl-1,3-oxazolidin-2-ones: Ideal Michael accepters to afford a virtually complete control of simple and face diastereoselectivity in addition reactions with glycine derivatives

      ORGANIC LETTERS
    27. Okayama, T; Burritt, A; Hruby, VJ
      4-Alkoxy-2-hydroxybenzaldehyde (AHB): A versatile aldehyde linker for solid-phase synthesis of C-terminal modified peptides and peptidomimetics

      ORGANIC LETTERS
    28. Soloshonok, VA; Cai, CZ; Hruby, VJ
      A practical asymmetric synthesis of enantiomerically pure 3-substituted pyroglutamic acids and related compounds

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    29. Ramachandran, J; Hruby, VJ
      Donald H. Yamashiro (1928-2000) - In memoriam

      JOURNAL OF PEPTIDE RESEARCH
    30. Balse, PM; Kim, HJ; Han, G; Hruby, VJ
      Evaluation of new base-labile 2-(4-nitrophenylsulfonyl) ethoxycarbonyl (Nsc)-amino acids for solid-phase peptide synthesis

      JOURNAL OF PEPTIDE RESEARCH
    31. Hruby, VJ
      Peptide science - whither thou goest?

      JOURNAL OF PEPTIDE RESEARCH
    32. Tang, XJ; Soloshonok, VA; Hruby, VJ
      Convenient, asymmetric synthesis of enantiomerically pure 2 ',6 '-dimethyltyrosine (DMT) via alkylation of chiral equivalent of nucleophilic glycine

      TETRAHEDRON-ASYMMETRY
    33. Kriss, CT; Lou, BS; Szabo, LZ; Mitchell, SA; Hruby, VJ; Polt, R
      Enkephalin-based drug design: conformational analysis of O-linked glycopeptides by NMR and molecular modeling

      TETRAHEDRON-ASYMMETRY
    34. Hruby, VJ; Balse, PM
      Conformational and topographical considerations in designing agonist peptidomimetics from peptide leads

      CURRENT MEDICINAL CHEMISTRY
    35. Hohmann, JG; Teal, TH; Clifton, DK; Davis, J; Hruby, VJ; Han, GX; Steiner, RA
      Differential role of melanocortins in mediating leptin's central effects on feeding and reproduction

      AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
    36. Haskell-Luevano, C; Lim, S; Yuan, W; Cone, RD; Hruby, VJ
      Structure activity studies of the melanocortin antagonist SHU9119 modifiedat the 6, 7, 8, and 9 positions

      PEPTIDES
    37. Wessells, H; Gralnek, D; Dorr, R; Hruby, VJ; Hadley, ME; Levine, N
      Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction

      UROLOGY
    38. Wang, SH; Tang, XJ; Hruby, VJ
      First stereoselective synthesis of an optically pure beta-substituted histidine: (2S,3S)-beta-methylhistidine

      TETRAHEDRON LETTERS
    39. Soloshonok, VA; Cai, CZ; Hruby, VJ
      A unique case of face diastereoselectivity in the Michael addition reactions between Ni(II)-complexes of glycine and chiral 3-(E-enoyl)-1,3-oxazolidin-2-ones

      TETRAHEDRON LETTERS
    40. Soloshonok, VA; Cai, CZ; Hruby, VJ
      Toward design of a practical methodology for stereocontrolled synthesis ofchi-constrained pyroglutamic acids and related compounds. Virtually complete control of simple diastereoselectivity in the Michael addition reactionsof glycine Ni(II) complexes with N-(enoyl)oxazolidinones

      TETRAHEDRON LETTERS
    41. Qiu, W; Soloshonok, VA; Cai, CZ; Tang, XJ; Hruby, VJ
      Convenient, large-scale asymmetric synthesis of enantiomerically pure trans-cinnamylglycine and -alpha-alanine

      TETRAHEDRON
    42. Bilsky, EJ; Qian, XH; Hruby, VJ; Porreca, F
      Antinociceptive activity of [beta-methyl-2 ',6 '-dimethyltyrosine(1)]-substituted cyclic [D-Pen(2),D-Pen(5)]enkephalin and [D-Ala(2),Asp(4)]deltorphin analogs

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    43. Soloshonok, VA; Cai, CZ; Hruby, VJ; Van Meervelt, L; Yamazaki, T
      Rational design of highly diastereoselective, organic base-catalyzed, room-temperature Michael addition reactions

      JOURNAL OF ORGANIC CHEMISTRY
    44. Witt, KA; Slate, CA; Egleton, RD; Huber, JD; Yamamura, HI; Hruby, VJ; Davis, TP
      Assessment of stereoselectivity of trimethylphenylalanine analogues of delta-opioid [D-Pen(2),D-Pen(5)]-enkephalin

      JOURNAL OF NEUROCHEMISTRY
    45. Trivedi, D; Lin, Y; Ahn, JM; Siegel, M; Mollova, NN; Schram, KH; Hruby, VJ
      Design and synthesis of conformationally constrained glucagon analogues

      JOURNAL OF MEDICINAL CHEMISTRY
    46. Bonner, GG; Davis, P; Stropova, D; Edsall, S; Yamamura, HI; Porreca, F; Hruby, VJ
      Opiate aromatic pharmacophore structure-activity relationships in CTAP analogues determined by topographical bias, two-dimensional NMR, and biological activity assays

      JOURNAL OF MEDICINAL CHEMISTRY
    47. Grieco, P; Balse, PM; Weinberg, D; MacNeil, T; Hruby, VJ
      D-amino acid scan of gamma-melanocyte-stimulating hormone: Importance of Trp(8) on human MC3 receptor selectivity

      JOURNAL OF MEDICINAL CHEMISTRY
    48. Bilsky, EJ; Egleton, RD; Mitchell, SA; Palian, MM; Davis, P; Huber, JD; Jones, H; Yamamura, HI; Janders, J; Davis, TP; Porreca, F; Hruby, VJ; Polt, R
      Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability

      JOURNAL OF MEDICINAL CHEMISTRY
    49. Ko, MCH; Willmont, KJ; Burritt, A; Hruby, VJ; Wood, JH
      Local inhibitory effects of dynorphin A-(1-17) on capsaicin-induced thermal allodynia in rhesus monkeys

      EUROPEAN JOURNAL OF PHARMACOLOGY
    50. Hosohata, K; Logan, JK; Varga, E; Burkey, TH; Vanderah, TW; Porreca, F; Hruby, VJ; Roeske, WR; Yamamura, HI
      The role of the G protein gamma(2) subunit in opioid antinociception in mice

      EUROPEAN JOURNAL OF PHARMACOLOGY
    51. Hosohata, Y; Vanderah, TW; Burkey, TH; Ossipov, MH; Kovelowski, CJ; Sora, I; Uhl, GR; Zhang, XY; Rice, KC; Roeske, WR; Hruby, VJ; Yamamura, HI; Lai, J; Porreca, F
      delta-opioid receptor agonists produce antinociception and [S-35]GTP gammaS binding in mu receptor knockout mice

      EUROPEAN JOURNAL OF PHARMACOLOGY
    52. Okura, T; Cowell, SM; Varga, E; Burkey, TH; Roeske, WR; Hruby, VJ; Yamamura, HI
      Differential down-regulation of the human delta-opioid receptor by SNC80 and [D-Pen(2),D-Pen(5)]enkephalin

      EUROPEAN JOURNAL OF PHARMACOLOGY
    53. Egleton, RD; Mitchell, SA; Huber, JD; Janders, J; Stropova, D; Polt, R; Yamamura, HI; Hruby, VJ; Davis, TP
      Improved bioavailability to the brain of glycosylated Met-enkephalin analogs

      BRAIN RESEARCH
    54. Shenderovich, MD; Liao, SB; Qian, XH; Hruby, VJ
      A three-dimensional model of the delta-opioid pharmacophore: Comparative molecular modeling of peptide and nonpeptide ligands

      BIOPOLYMERS
    55. Salamon, Z; Cowell, S; Varga, E; Yamamura, HI; Hruby, VJ; Tollin, G
      Plasmon resonance studies of agonist/antagonist binding to the human delta-opioid receptor: New structural insights into receptor-ligand interactions

      BIOPHYSICAL JOURNAL
    56. Hruby, VJ; Han, GX
      The molecular pharmacology of alpha-melanocyte stimulating hormone - Structure-activity relationships for melanotropins at melanocortin receptors

      MELANOCORTIN RECEPTORS
    57. Hruby, VJ
      A call for greater participation in The Journal of Peptide Research

      JOURNAL OF PEPTIDE RESEARCH
    58. Bartosz-Bechowski, H; Davis, P; Slaninova, J; Malatynska, E; Stropova, D; Porreca, F; Yamamura, HI; Hruby, VJ
      Cyclic enkephalin analogs that are hybrids of DPDPE-related peptides and Metenkephalin-Arg-Gly-Leu: prohormone analogs that retain good potency and selectivity for delta opioid receptors

      JOURNAL OF PEPTIDE RESEARCH
    59. Lipkowski, AW; Misicka, A; Davis, P; Stropova, D; Janders, J; Lachwa, M; Porreca, F; Yamamura, HI; Hruby, VJ
      Biological activity of fragments and analogues of the potent dimeric opioid peptide, biphalin

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    60. Soloshonok, VA; Cai, CZ; Hruby, VJ
      Asymmetric Michael addition reactions of chiral Ni(II)-complex of glycine with (N-trans-enoyl)oxazolidines: improved reactivity and stereochemical outcome

      TETRAHEDRON-ASYMMETRY
    61. Huang, QH; Hruby, VJ; Tatro, JB
      Role of central melanocortins in endotoxin-induced anorexia

      AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
    62. Kovelowski, CJ; Ossipov, MH; Hruby, VJ; Porreca, F
      Lesions of the dorsolateral funiculus block supraspinal opioid delta receptor mediated antinociception in the rat

      PAIN
    63. Gentry, CL; Egleton, RD; Gillespie, T; Abbruscato, TJ; Bechowski, HB; Hruby, VJ; Davis, TP
      The effect of halogenation on blood-brain barrier permeability of a novel peptide drug

      PEPTIDES
    64. Soloshonok, VA; Cai, CZ; Hruby, VJ; Van Meervelt, L; Mischenko, N
      Stereochemically defined C-substituted glutamic acids and their derivatives. 1. An efficient asymmetric synthesis of (2S,3S)-3-methyl- and -3-trifluoromethylpyroglutamic acids

      TETRAHEDRON
    65. Soloshonok, VA; Cai, CZ; Hruby, VJ
      Asymmetric synthesis of novel highly sterically constrained (2S,3S)-3-methyl-3-trifluoromethyl- and (2S,3S,4R)-3-trifluoromethyl-4-methylpyroglutamicacids

      TETRAHEDRON
    66. Tang, QB; Gandhoke, R; Burritt, A; Hruby, VJ; Porreca, F; Lai, J
      High-affinity interaction of (des-tyrosyl) dynorphin A(2-17) with NMDA receptors

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    67. Alfaro-Lopez, J; Okayama, T; Hosohata, K; Davis, P; Porreca, F; Yamamura, HI; Hruby, VJ
      Exploring the structure-activity relationships of [1-(4-tert-butyl-3 '-hydroxy)benzhydryl-4-benzylpiperazine] (SL-3111), a high-affinity and selective delta-opioid receptor nonpeptide agonist ligand

      JOURNAL OF MEDICINAL CHEMISTRY
    68. Hosohata, K; Burkey, TH; Alfaro-Lopez, J; Hruby, VJ; Roeske, WR; Yamamura, HI
      (2S,3R)TMT-L-Tic-OH is a potent inverse agonist at the human delta-opioid receptor

      EUROPEAN JOURNAL OF PHARMACOLOGY
    69. Kovelowski, CJ; Bian, D; Hruby, VJ; Lai, J; Ossipov, MH; Porreca, F
      Selective opioid delta agonists elicit antinociceptive supraspinal/spinal synergy in the rat

      BRAIN RESEARCH
    70. Hruby, VJ; Agnes, RS
      Conformation-activity relationships of opioid peptides with selective activities at opioid receptors

      BIOPOLYMERS
    71. Prabhu, NV; Perkyns, JS; Pettitt, BM; Hruby, VJ
      Structure and dynamics of alpha-MSH using DRISM integral equation theory and stochastic dynamics

      BIOPOLYMERS
    72. Hruby, VJ; Slate, CA
      Amino acid mimetics and design of peptidomimetics for opioid and melanocortin receptors: General perspectives

      ADVANCES IN AMINO ACID MIMETICS AND PEPTIDOMIMETICS, VOL 2, 1999
    73. ALOBEIDI F; OCONNOR SD; JOB C; HRUBY VJ; PETTITT BM
      NMR AND QUENCHED MOLECULAR-DYNAMICS STUDIES OF SUPERPOTENT LINEAR ANDCYCLIC ALPHA-MELANOTROPINS

      The journal of peptide research
    74. Hruby, VJ
      Untitled

      JOURNAL OF PEPTIDE RESEARCH
    75. LI GG; HAQ W; XIANG L; LOU BS; HUGHES R; DELEON IA; DAVIS P; GILLESPIE TJ; ROMANOWSKI M; ZHU XY; MISICKA A; LIPKOWSKI AW; PORRECA F; DAVIS TP; YAMAMURA HI; OBRIEN DF; HRUBY VJ
      MODIFICATIONS OF THE 4,4'-RESIDUES AND SAR STUDIES OF BIPHALIN, A HIGHLY POTENT OPIOID RECEPTOR ACTIVE PEPTIDE

      Bioorganic & medicinal chemistry letters
    76. HOSOHATA K; BURKEY TH; ALFAROLOPEZ J; VARGA E; HRUBY VJ; ROESKE WR; YAMAMURA HI
      ENDOMORPHIN-1 AND ENDOMORPHIN-2 ARE PARTIAL AGONISTS AT THE HUMAN MU-OPIOID RECEPTOR

      The FASEB journal
    77. HUANG QH; HRUBY VJ; TATRO JB
      SYSTEMIC ALPHA-MSH SUPPRESSES LPS FEVER VIA CENTRAL MELANOCORTIN RECEPTORS INDEPENDENTLY OF ITS SUPPRESSION OF CORTICOSTERONE AND IL-6 RELEASE

      American journal of physiology. Regulatory, integrative and comparative physiology
    78. NI XP; KESTERSON RA; SHARMA SD; HRUBY VJ; CONE RD; WIEDEMANN E; HUMPHREYS MH
      PREVENTION OF REFLEX NATRIURESIS AFTER ACUTE UNILATERAL NEPHRECTOMY BY MELANOCORTIN RECEPTOR ANTAGONISTS

      American journal of physiology. Regulatory, integrative and comparative physiology
    79. HAN YL; HRUBY VJ
      LEWIS-ACID PROMOTED CONJUGATE ADDITION OF VINYLMAGNESIUM BROMIDE TO CHIRAL ALPHA,BETA-UNSATURATED N-ACYL OXAZOLIDINONES (VOL 38, PG 7317, 1997)

      Tetrahedron letters
    80. LIN J; LIAO S; HRUBY VJ
      ASYMMETRIC SYNTHESES OF HIGHLY HYDROPHOBIC CHIMERIC AROMATIC-AMINO-ACIDS - 2-AMINO-3,3-DIARYLPROPIONIC ACIDS

      Tetrahedron letters
    81. BURKEY TH; EHLERT FJ; HOSOHATA Y; QUOCK RM; COWELL S; HOSOHATA K; VARGA E; STROPOVA D; LI X; SLATE C; NAGASE H; PORRECA F; HRUBY VJ; ROESKE WR; YAMAMURA HI
      THE EFFICACY OF DELTA-OPIOID RECEPTOR-SELECTIVE DRUGS

      Life sciences
    82. SLANINOVA J; APPLEYARD SM; MISICKA A; LIPKOWSKI AW; KNAPP RJ; WEBER SJ; DAVIS TP; YAMAMURA HI; HRUBY VJ
      [I-125-TYR(1)]BIPHALIN BINDING TO OPIOID RECEPTORS OF RAT-BRAIN AND NG108-15 CELL-MEMBRANES

      Life sciences
    83. WESSELLS H; FUCIARELLI K; HANSEN J; HADLEY ME; HRUBY VJ; DORR R; LEVINE N
      SYNTHETIC MELANOTROPIC PEPTIDE INITIATES ERECTIONS IN MEN WITH PSYCHOGENIC ERECTILE DYSFUNCTION - DOUBLE-BLIND, PLACEBO-CONTROLLED CROSSOVER STUDY

      The Journal of urology
    84. LIAO SB; ALFAROLOPEZ J; SHENDEROVICH MD; HOSOHATA K; LIN J; LI XP; STROPOVA D; DAVIS P; JERNIGAN KA; PORRECA F; YAMAMURA HI; HRUBY VJ
      DE-NOVO DESIGN, SYNTHESIS, AND BIOLOGICAL-ACTIVITIES OF HIGH-AFFINITYAND SELECTIVE NONPEPTIDE AGONISTS OF THE DELTA-OPIOID RECEPTOR

      Journal of medicinal chemistry
    85. STURM NS; LIN Y; BURLEY SK; KRSTENANSKY JL; AHN JM; AZIZEH BY; TRIVEDI D; HRUBY VJ
      STRUCTURE - FUNCTION STUDIES ON POSITION-17, POSITION-18, AND POSITION-21 REPLACEMENT ANALOGS OF GLUCAGON - THE IMPORTANCE OF CHARGED RESIDUES AND SALT BRIDGES IN GLUCAGON BIOLOGICAL-ACTIVITY

      Journal of medicinal chemistry
    86. ALFAROLOPEZ J; YUAN W; PHAN BC; KAMATH J; LOU Q; LAM KS; HRUBY VJ
      DISCOVERY OF A NOVEL SERIES OF POTENT AND SELECTIVE SUBSTRATE-BASED INHIBITORS OF P60(C-SRC) PROTEIN-TYROSINE KINASE - CONFORMATIONAL AND TOPOGRAPHICAL CONSTRAINTS IN PEPTIDE DESIGN

      Journal of medicinal chemistry
    87. HOSOHATA K; BURKEY TH; ALFAROLOPEZ J; VARGA E; HRUBY VJ; ROESKE WR; YAMAMURA HI
      ENDOMORPHIN-1 AND ENDOMORPHIN-2 ARE PARTIAL AGONISTS AT THE HUMAN MU-OPIOID RECEPTOR

      European journal of pharmacology
    88. NIKIFOROVICH GV; SHARMA SD; HADLEY ME; HRUBY VJ
      STUDIES OF CONFORMATIONAL ISOMERISM IN ALPHA-MELANOCYTE-STIMULATING HORMONE BY DESIGN OF CYCLIC ANALOGS

      Biopolymers
    89. LIAN SB; SHENDEROVICH MD; ZHANG ZG; MALETINSKA L; SLANINOVA J; HRUBY VJ
      SUBSTITUTION OF THE SIDE-CHAIN-CONSTRAINED AMINO-ACIDS BETA-METHYL-2',6'-DIMETHYL-4'-METHOXYTYROSINE IN POSITION-2 OF A BICYCLIC OXYTOCIN ANALOG PROVIDES UNIQUE INSIGHTS INTO THE BIOACTIVE TOPOGRAPHY OF OXYTOCIN ANTAGONISTS

      Journal of the American Chemical Society
    90. UHRIN D; BATTA G; HRUBY VJ; BARLOW PN; KOVER KE
      SENSITIVITY-ENHANCED AND GRADIENT-ENHANCED HETERO (OMEGA(1)) HALF-FILTERED TOCSY EXPERIMENT FOR MEASURING LONG-RANGE COUPLING-CONSTANTS

      Journal of magnetic resonance [1997]
    91. KOVER KE; UHRIN D; HRUBY VJ
      GUADIENT-ENHANCED AND SENSITIVITY-ENHANCED TOCSY EXPERIMENTS

      Journal of magnetic resonance [1997]
    92. HRUBY VJ
      UNTITLED

      The journal of peptide research
    93. HAASETH RC; ZALEWSKA T; DAVIS P; YAMAMURA HI; PORRECA F; HRUBY VJ
      PARASUBSTITUTED PHENYLALANINE-4 ANALOGS OF [L-ALA(3)]DPDPE - HIGHLY SELECTIVE DELTA-OPIOID RECEPTOR LIGANDS

      The journal of peptide research
    94. MISICKA A; CAVAGNERO S; HORVATH R; DAVIS P; PORRECA F; YAMAMURA HI; HRUBY VJ
      SYNTHESIS AND BIOLOGICAL PROPERTIES OF BETA-MEPHE(3) ANALOGS OF DELTORPHIN-I AND DERMENKEPHALIN - INFLUENCE OF BIASED CHI(1) OF PHE(3) RESIDUES ON PEPTIDE RECOGNITION FOR DELTA-OPIOID RECEPTORS

      The journal of peptide research
    95. STURM NS; HUTZLER AM; DAVID CS; AZIZEH BY; TRIVEDI A; HRUBY VJ
      STRUCTURE-ACTIVITY STUDIES OF HYDROPHOBIC AMINO-ACID REPLACEMENTS AT POSITION-9, POSITION-11 AND POSITION-16 OF GLUCAGON

      The journal of peptide research
    96. HRUBY VJ; AHN JM; LIAO SB
      SYNTHESIS OF OLIGOPEPTIDE AND PEPTIDOMIMETIC LIBRARIES

      CURRENT OPINION IN CHEMICAL BIOLOGY
    97. HRUBY VJ
      PROSPECTS FOR PEPTIDOMIMETIC DRUG DESIGN

      Drug discovery today
    98. PATEL D; MCKINLEY BD; DAVIS TP; PORRECA F; YAMAMURA HI; HRUBY VJ
      PEPTIDE TARGETING AND DELIVERY ACROSS THE BLOOD-BRAIN-BARRIER UTILIZING SYNTHETIC TRIGLYCERIDE ESTERS - DESIGN, SYNTHESIS, AND BIOACTIVITY

      Bioconjugate chemistry
    99. LIAO SB; LIN J; SHENDEROVICH MD; HAN YL; HASOHATA K; DAVIS P; QIU W; PORRECA F; YAMAMURA HI; HRUBY VJ
      THE STEREOCHEMICAL REQUIREMENTS OF THE NOVEL DELTA-OPIOID SELECTIVE DIPEPTIDE ANTAGONIST TMT-TIC

      Bioorganic & medicinal chemistry letters
    100. LIN J; LIAO SB; HAN YL; QIU W; HRUBY VJ
      ASYMMETRIC-SYNTHESIS OF ALL 4 ISOMERS OF TOGOGRAPHICALLY CONSTRAINED NOVEL AMINO-ACIDS - BETA-ISOPROPYLTYROSINES

      Tetrahedron : asymmetry


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Documento generato il 30/10/20 alle ore 07:24:34