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    1. Choi, K; Hamilton, AD
      A dual channel fluorescence chemosensor for anions involving intermolecular excited state proton transfer

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    2. Hamilton, AD; Kirby, AJ
      Model systems - Artificial models of protein function - Editorial overview

      CURRENT OPINION IN CHEMICAL BIOLOGY
    3. Wei, Y; McLendon, GL; Hamilton, AD; Case, MA; Purring, CB; Lin, Q; Park, HS; Lee, CS; Yu, TN
      Disruption of protein-protein interactions: design of a synthetic receptorthat blocks the binding of cytochrome c to cytochrome c peroxidase

      CHEMICAL COMMUNICATIONS
    4. Hamuro, Y; Hamilton, AD
      Functionalized oligoanthranilamides: Modular and conformationally controlled scaffolds

      BIOORGANIC & MEDICINAL CHEMISTRY
    5. Ohkanda, J; Lockman, JW; Yokoyama, K; Gelb, MH; Croft, SL; Kendrick, H; Harrell, MI; Feagin, JE; Blaskovich, MA; Sebti, SM; Hamilton, AD
      Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    6. Estroff, LA; Hamilton, AD
      At the interface of organic and inorganic chemistry: Bioinspired synthesisof composite materials

      CHEMISTRY OF MATERIALS
    7. Lee, CS; Lee, KI; Hamilton, AD
      Constrained analogs of methionine: asymmetric synthesis of chi-angle restricted methionine derivatives through [3.1.0]-gamma-lactone cyclopropane ring opening

      TETRAHEDRON LETTERS
    8. Lee, CS; Lee, KI; Hamilton, AD
      Constrained analogs of methionine: asymmetric synthesis of chi-angle restricted methionine derivatives through [3.1.0]-gamma-lactone cyclopropane ring opening (vol 42, pg 211, 2001)

      TETRAHEDRON LETTERS
    9. Teng, S; Sun, JZ; Irby, R; Hamilton, AD; Sebti, S; Yeatman, TJ
      v-Src transformation is mediated through farnesylated proteins

      JOURNAL OF SURGICAL RESEARCH
    10. Linton, BR; Goodman, MS; Fan, E; van Arman, SA; Hamilton, AD
      Thermodynamic aspects of dicarboxylate recognition by simple artificial receptors

      JOURNAL OF ORGANIC CHEMISTRY
    11. Turkson, J; Ryan, D; Kim, JS; Zhang, Y; Chen, Z; Haura, E; Laudano, A; Sebti, S; Hamilton, AD; Jove, R
      Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    12. Crespo, NC; Ohkanda, J; Yen, TJ; Hamilton, AD; Sebti, SM
      The farnesyltransferase inhibitor, FTI-2153, blocks bipolar spindle formation and chromosome alignment and causes prometaphase accumulation during mitosis of human lung cancer cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    13. Sun, JZ; Nam, SK; Lee, CS; Li, BY; Coppola, D; Hamilton, AD; Dou, QP; Sebti, SM
      CEP1612, a dipeptidyl proteasome inhibitor, induces p21(WAF1) and p27(KIP1) expression and apoptosis and inhibits the growth of the human lung adenocarcinoma A-549 in nude mice

      CANCER RESEARCH
    14. Kucich, U; Rosenbloom, JC; Herrick, DJ; Abrams, WR; Hamilton, AD; Sebti, SM; Rosenbloom, J
      Signaling events required for transforming growth factor-beta stimulation of connective tissue growth factor expression by cultured human lung fibroblasts

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    15. Orner, BP; Ernst, JT; Hamilton, AD
      Toward proteomimetics: Terphenyl derivatives as structural and functional mimics of extended regions of an alpha-helix

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    16. Choi, KH; Hamilton, AD
      Selective anion binding by a macrocycle with convergent hydrogen bonding functionality

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    17. Knowles, D; Sun, JZ; Rosenberg, S; Sebti, SM; Hamilton, AD
      Peptidomimetic-based inhibitors of farnesyltransferase

      FARNESYLTRANSFERASE INHIBITORS IN CANCER THERAPY
    18. Bernhard, EJ; Muschel, RH; Cohen-Jonathan, E; Favre, G; Hamilton, AD; Sebti, SM; McKenna, WG
      Prenyltransferase inhibitors as radiosensitizers

      FARNESYLTRANSFERASE INHIBITORS IN CANCER THERAPY
    19. Sebti, SM; Hamilton, AD
      Farnesyltransferase and geranylgeranyltransferase I inhibitors as novel agents for cancer and cardiovascular diseases

      FARNESYLTRANSFERASE INHIBITORS IN CANCER THERAPY
    20. Gelb, MH; Buckner, FS; Yokoyama, K; Ohkanda, J; Hamilton, AD; Nguyen, L; Rossi-Bergmann, B; Stuart, KD; Sebti, SM; Van Voorhis, WC
      Protein prenylation in trypanosomatids - A new piggy-back medicinal chemistry target for the development of agents against tropical diseases

      FARNESYLTRANSFERASE INHIBITORS IN CANCER THERAPY
    21. Jain, RK; Hamilton, AD
      Protein surface recognition by synthetic receptors based on a tetraphenylporphyrin scaffold

      ORGANIC LETTERS
    22. Estroff, LA; Hamilton, AD
      Effective gelation of water using a series of bis-urea dicarboxylic acids

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    23. Salvatella, X; Peczuh, MW; Gairi, M; Jain, RK; Sanchez-Quesada, J; de Mendoza, J; Hamilton, AD; Giralt, E
      Side chain elongation causes a change from enthalpy driven to entropy driven binding in the molecular recognition of tetraanionic peptides

      CHEMICAL COMMUNICATIONS
    24. Sebti, SM; Hamilton, AD
      Farnesyltransferase and geranylgeranyltransferase I inhibitors in cancer therapy: important mechanistic and bench to bedside issues

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    25. Blaskovich, MA; Lin, Q; Delarue, FL; Sun, J; Park, HS; Coppola, D; Hamilton, AD; Sebti, SM
      Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice

      NATURE BIOTECHNOLOGY
    26. Sebti, SM; Hamilton, AD
      Design of growth factor antagonists with antiangiogenic and antitumor properties

      ONCOGENE
    27. Sebti, SM; Hamilton, AD
      Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: Lessons from mechanism and bench-to-bedside translational studies

      ONCOGENE
    28. Adnane, J; Bizouarn, FA; Chen, Z; Ohkanda, J; Hamilton, AD; Munoz-Antonia, T; Sebti, SM
      Inhibition of farnesyltransferase increases TGF beta type II receptor expression and enhances the responsiveness of human cancer cells to TGF beta

      ONCOGENE
    29. Linton, BR; Goodman, MS; Hamilton, AD
      Nitronate anion recognition and modulation of ambident reactivity by hydrogen-bonding receptors

      CHEMISTRY-A EUROPEAN JOURNAL
    30. Carloni, V; Pinzani, M; Giusti, S; Romanelli, RG; Parola, M; Bellomo, G; Failli, P; Hamilton, AD; Sebti, SM; Laffi, G; Gentilini, P
      Tyrosine phosphorylation of focal adhesion kinase by PDGF is dependent on Ras in human hepatic stellate cells

      HEPATOLOGY
    31. Jiang, K; Coppola, D; Crespo, NC; Nicosia, SV; Hamilton, AD; Sebti, SM; Cheng, JQ
      The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

      MOLECULAR AND CELLULAR BIOLOGY
    32. Lantry, LE; Zhang, ZQ; Yao, RS; Crist, KA; Wang, Y; Ohkanda, J; Hamilton, AD; Sebti, SM; Lubet, RA; You, M
      Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

      CARCINOGENESIS
    33. Melendez, RE; Carr, AJ; Linton, BR; Hamilton, AD
      Controlling hydrogen bonding: From molecular recognition to organogelation

      MOLECULAR SELF-ASSEMBLY
    34. Sebti, SM; Hamilton, AD
      Inhibition of Rho GTPases using protein geranylgeranyltransferase I inhibitors

      REGULATORS AND EFFECTORS OF SMALL GTPASES, PT D
    35. Kothare, MA; Ohkanda, J; Lockman, JW; Qian, YM; Blaskovich, MA; Sebti, SM; Hamilton, AD
      Development of a tripeptide mimetic strategy for the inhibition of proteinfarnesyltransferase

      TETRAHEDRON
    36. Zafar, A; Geib, SJ; Hamuro, Y; Carr, AJ; Hamilton, AD
      Hydrogen bonding control of molecular self-assembly: Aggregation behavior of acylaminopyridine-carboxylic acid derivatives in solution and the solid state

      TETRAHEDRON
    37. Cohen-Jonathan, E; Muschel, RJ; McKenna, WG; Evans, SM; Cerniglia, G; Mick, R; Kusewitt, D; Sebti, SM; Hamilton, AD; Oliff, A; Kohl, N; Gibbs, JB; Bernhard, EJ
      Farnesyltransferase inhibitors potentiate the antitumor effect of radiation on a human tumor xenograft expressing activated HRAS

      RADIATION RESEARCH
    38. Linton, BR; Carr, AJ; Orner, BP; Hamilton, AD
      A versatile one-pot synthesis of 1,3-substituted guanidines from carbamoylisothiocyanates

      JOURNAL OF ORGANIC CHEMISTRY
    39. Wei, S; Gilvary, DL; Corliss, BC; Sebti, S; Sun, JZ; Straus, DB; Leibson, PJ; Trapani, JA; Hamilton, AD; Weber, MJ; Djeu, JY
      Direct tumor lysis by NK cells uses a Ras-independent mitogen-activated protein kinase signal pathway

      JOURNAL OF IMMUNOLOGY
    40. Allal, C; Favre, G; Couderc, B; Salicio, S; Sixou, S; Hamilton, AD; Sebti, SM; Lajoie-Mazenc, I; Pradines, A
      RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription

      JOURNAL OF BIOLOGICAL CHEMISTRY
    41. Peczuh, MW; Hamilton, AD
      Peptide and protein recognition by designed molecules

      CHEMICAL REVIEWS
    42. Rosenbloom, J; Saitta, B; Gaidarova, S; Sandorfi, N; Rosenbloom, JC; Abrams, WR; Hamilton, AD; Sebti, SM; Kucich, U; Jimenez, SA
      Inhibition of type I collagen gene expression in normal and systemic sclerosis fibroblasts by a specific inhibitor of geranylgeranyl transferase I

      ARTHRITIS AND RHEUMATISM
    43. Kucich, U; Rosenbloom, JC; Shen, G; Abrams, WR; Hamilton, AD; Sebti, SM; Rosenbloom, J
      TGF-beta 1 stimulation of fibronectin transcription in cultured human lungfibroblasts requires active geranylgeranyl transferase I, phosphatidylcholine-specific phospholipase C, protein kinase C-delta, and p38, but not erk1/erk2

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    44. Ghosh, I; Hamilton, AD; Regan, L
      Antiparallel leucine zipper-directed protein reassembly: Application to the green fluorescent protein

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    45. Zimmerman, SC; Hamilton, AD
      Model systems

      CURRENT OPINION IN CHEMICAL BIOLOGY
    46. Linton, B; Hamilton, AD
      Host-guest chemistry: combinatorial receptors

      CURRENT OPINION IN CHEMICAL BIOLOGY
    47. Liu, SH; Hamilton, AD
      Rapid and highly base selective RNA cleavage by a dinuclear Cu(II) complex

      CHEMICAL COMMUNICATIONS
    48. Yang, J; Melendez, R; Geib, SJ; Hamilton, AD
      Hydrogen bonding aggregation of a series of bis-amidinium halide salts in the solid state

      STRUCTURAL CHEMISTRY
    49. Qian, YM; Marugan, JJ; Fossum, RD; Vogt, A; Sebti, SM; Hamilton, AD
      Probing the hydrophobic pocket of farnesyltransferase: Aromatic substitution of CAAX peptidomimetics leads to highly potent inhibitors

      BIOORGANIC & MEDICINAL CHEMISTRY
    50. Pollack, IF; Bredel, M; Erff, M; Hamilton, AD; Sebti, SM
      Inhibition of Ras and related guanosine triphosphate-dependent proteins asa therapeutic strategy for blocking malignant glioma growth: II - Preclinical studies in a nude mouse model

      NEUROSURGERY
    51. Linton, B; Hamilton, AD
      Calorimetric investigation of guanidinium-carboxylate interactions

      TETRAHEDRON
    52. Shi, C; Huang, Z; Kilic, S; Xu, J; Enick, RM; Beckman, EJ; Carr, AJ; Melendez, RE; Hamilton, AD
      The gelation of CO2: A sustainable route to the creation of microcellular materials

      SCIENCE
    53. Cohen-Jonathan, E; Toulas, C; Ader, I; Monteil, S; Allal, C; Bonnet, J; Hamilton, AD; Sebti, SM; Daly-Schveitzer, N; Favre, G
      The farnesyltransferase inhibitor FTI-277 suppresses the 24-kDa FGF2-induced radioresistance in HeLa cells expressing wild-type RAS

      RADIATION RESEARCH
    54. Vasudevan, A; Qian, YM; Vogt, A; Blaskovich, MA; Ohkanda, J; Sebti, SM; Hamilton, AD
      Potent, highly selective, and non-thiol inhibitors of protein geranylgeranyltransferase-I

      JOURNAL OF MEDICINAL CHEMISTRY
    55. Liu, L; Moesner, P; Kovach, NL; Bailey, R; Hamilton, AD; Sebti, SM; Harlan, JM
      Integrin-dependent leukocyte adhesion involves geranylgeranylated protein(s)

      JOURNAL OF BIOLOGICAL CHEMISTRY
    56. Sung, JZ; Qian, YM; Chen, Z; Marfurt, J; Hamilton, AD; Sebti, SM
      The geranylgeranyltransferase I inhibitor GGTI-298 induces hypophosphorylation of retinoblastoma and partner switching of cyclin-dependent kinase inhibitors - A potential mechanism for GGTI-298 antitumor activity

      JOURNAL OF BIOLOGICAL CHEMISTRY
    57. Mazet, JL; Padieu, M; Osman, H; Maume, G; Mailliet, P; Dereu, N; Hamilton, AD; Lavelle, F; Sebti, SM; Maume, BF
      `Combination of the novel farnesyltransferase inhibitor RPR130401 and the geranylgeranyltransferase-1 inhibitor GGTI-298 disrupts MAP kinase activation and G(1)-S transition in Ki-Ras-overexpressing transformed adrenocortical cells

      FEBS LETTERS
    58. Sun, JZ; Blaskovich, MA; Knowles, D; Qian, YM; Ohkanda, J; Bailey, RD; Hamilton, AD; Sebti, SM
      Antitumor efficacy of a novel class of non-thiol-containing peptidomimeticinhibitors of farnesyltransferase and geranylgeranyltransferase I: Combination therapy with the cytotoxic agents cisplatin, taxol, and gemcitabine

      CANCER RESEARCH
    59. Haack, T; Peczuh, MW; Salvatella, X; Sanchez-Quesada, J; de Mendoza, J; Hamilton, AD; Giralt, E
      Surface recognition and helix stabilization of a tetraaspartate peptide byshape and electrostatic complementarity of an artificial receptor

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    60. Park, HS; Lin, Q; Hamilton, AD
      Protein surface recognition by synthetic receptors: A route to novel submicromolar inhibitors for alpha-chymotrypsin

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    61. SHAO YH; LINTON B; HAMILTON AD; WEBER SG
      ELECTROCHEMICAL STUDIES ON MOLECULAR RECOGNITION OF ANIONS - COMPLEX-FORMATION BETWEEN XYLYLENYL BIS-IMINOIMIDAZOLINIUM AND DICARBOXYLATES IN NITROBENZENE AND WATER

      Journal of electroanalytical chemistry [1992]
    62. SUKHAREVSKY AP; READ I; LINTON B; HAMILTON AD; WALDECK DH
      EXPERIMENTAL MEASUREMENTS OF LOW-FREQUENCY INTERMOLECULAR HOST-GUEST DYNAMICS

      JOURNAL OF PHYSICAL CHEMISTRY B
    63. SEBTI SM; HAMILTON AD
      NEW APPROACHES TO ANTICANCER DRUG DESIGN BASED ON THE INHIBITION OF FARNESYLTRANSFERASE

      Drug discovery today
    64. ZAFAR A; GEIB SJ; HAMURO Y; HAMILTON AD
      NEW SUPRAMOLECULAR ARRAYS BASED ON INTERACTIONS BETWEEN CARBOXYLATE AND UREA GROUPS - SOLID-STATE AND SOLUTION BEHAVIOR

      New journal of chemistry
    65. STARK WW; BLASKOVICH MA; JOHNSON BA; QIAN YM; VASUDEVAN A; PITT B; HAMILTON AD; SEBTI SM; DAVIES P
      INHIBITING GERANYLGERANYLATION BLOCKS GROWTH AND PROMOTES APOPTOSIS IN PULMONARY VASCULAR SMOOTH-MUSCLE CELLS

      American journal of physiology. Lung cellular and molecular physiology
    66. QIAN YM; VOGT A; VASUDEVAN A; SEBTI SM; HAMILTON AD
      SELECTIVE-INHIBITION OF TYPE-I GERANYLGERANYLTRANSFERASE IN-VITRO ANDIN WHOLE CELLS BY CAAL PEPTIDOMIMETICS

      Bioorganic & medicinal chemistry
    67. WEINER WS; HAMILTON AD
      SYNTHESIS AND BINDING-STUDIES OF A 1-ALKYL-3,6-DIAMINO-4-QUINOLONE BASED RECEPTOR FOR N-ACYLATED DIPEPTIDES

      Bioorganic & medicinal chemistry letters
    68. Sharma, TA; Carr, AJ; Davis, RS; Reynolds, LJ; Hamilton, AD
      Aromatic analogs of arcaine inhibit MK-801 binding to the NMDA receptor

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    69. SUN JZ; QIAN YM; HAMILTON AD; SEBTI SM
      BOTH FARNESYLTRANSFERASE AND GERANYLGERANYLTRANSFERASE-I INHIBITORS ARE REQUIRED FOR INHIBITION OF ONCOGENIC K-RAS PRENYLATION BUT EACH ALONE IS SUFFICIENT TO SUPPRESS HUMAN TUMOR-GROWTH IN NUDE-MOUSE XENOGRAFTS

      Oncogene
    70. LIN Q; GEIB SJ; HAMILTON AD
      1-PHENYL-1H-PYRROLE-2,5-DICARBOXYLIC ACID-DERIVATIVES AS VERSATILE HYDROGEN-BONDING MOTIFS FOR THE FORMATION OF ONE-DIMENSIONAL, 2-DIMENSIONAL AND 3-DIMENSIONAL NETWORKS IN THE SOLID-STATE

      Journal of the Chemical Society. Perkin transactions. II (Print)
    71. ADNANE J; BIZOUARN FA; QIAN YM; HAMILTON AD; SEBTI SM
      P21(WAF1 CIP1) IS UP-REGULATED BY THE GERANYLGERANYLTRANSFERASE-I INHIBITOR GGTI-298 THROUGH A TRANSFORMING-GROWTH-FACTOR BETA-RESPONSIVE AND SP1-RESPONSIVE ELEMENT - INVOLVEMENT OF THE SMALL GTPASE RHOA/

      Molecular and cellular biology (Print)
    72. BREDEL M; POLLACK IF; FREUND JM; HAMILTON AD; SEBTI SM
      INHIBITION OF RAS AND RELATED G-PROTEINS AS A THERAPEUTIC STRATEGY FOR BLOCKING MALIGNANT GLIOMA GROWTH

      Neurosurgery
    73. CARR AJ; MELENDEZ R; GEIB SJ; HAMILTON AD
      THE DESIGN OF ORGANIC GELATORS - SOLUTION AND SOLID-STATE PROPERTIES OF A FAMILY OF BIS-UREAS

      Tetrahedron letters
    74. BERNHARD EJ; MCKENNA WG; HAMILTON AD; SEBTI SM; QIAN YM; WU JM; MUSCHEL RJ
      INHIBITING RAS PRENYLATION INCREASES THE RADIOSENSITIVITY OF HUMAN TUMOR-CELL LINES WITH ACTIVATING MUTATIONS OF RAS ONCOGENES

      Cancer research
    75. Lin, Q; Park, HS; Hamuro, Y; Lee, CS; Hamilton, AD
      Protein surface recognition by synthetic agents: Design and structural requirements of a family of artificial receptors that bind to cytochrome c

      BIOPOLYMERS
    76. KUCICH U; ROSENBLOOM JC; SHEN G; ABRAMS WR; BLASKOVICH MA; HAMILTON AD; OHKANDA J; SEBTI SM; ROSENBLOOM J
      REQUIREMENT FOR GERANYLGERANYL TRANSFERASE-I AND ACYL TRANSFERASE IN THE TGF-BETA-STIMULATED PATHWAY LEADING TO ELASTIN MESSENGER-RNA STABILIZATION

      Biochemical and biophysical research communications (Print)
    77. LIU SH; LUO ZY; HAMILTON AD
      RAPID AND HIGHLY SELECTIVE CLEAVAGE OF RIBONUCLEOSIDE 2',3'-CYCLIC MONOPHOSPHATES BY DINUCLEAR CU-II COMPLEXES

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    78. HAMURO Y; CALAMA MC; PARK HS; HAMILTON AD
      A CALIXARENE WITH 4 PEPTIDE LOOPS - AN ANTIBODY MIMIC FOR RECOGNITIONOF PROTEIN SURFACES

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    79. CHEN HD; WEINER WS; HAMILTON AD
      RECOGNITION OF NEUTRAL SPECIES WITH SYNTHETIC RECEPTORS

      CURRENT OPINION IN CHEMICAL BIOLOGY
    80. FAN EK; VICENT C; HAMILTON AD
      MOLECULAR RECOGNITION AND CATALYSIS - INCORPORATION OF AN OXYANION HOLE INTO A SYNTHETIC RECEPTOR

      New journal of chemistry
    81. ALBERT JS; PECZUH MW; HAMILTON AD
      DESIGN, SYNTHESIS AND EVALUATION OF SYNTHETIC RECEPTORS FOR THE RECOGNITION OF ASPARTATE PAIRS IN AN ALPHA-HELICAL CONFORMATION

      Bioorganic & medicinal chemistry
    82. LIU SH; HAMILTON AD
      CATALYSIS OF PHOSPHODIESTER TRANSESTERIFICATION BY DINUCLEAR CU(II) COMPLEXES - THE ROLE OF THE 2ND CU(II) ION

      Bioorganic & medicinal chemistry letters
    83. LERNER EC; ZHANG TT; KNOWLES DB; QIAN YM; HAMILTON AD; SEBTI SM
      INHIBITION OF THE PRENYLATION OF K-RAS, BUT NOT H-RAS OR N-RAS, IS HIGHLY RESISTANT TO CAAX PEPTIDOMIMETICS AND REQUIRES BOTH A FARNESYLTRANSFERASE AND A GERANYLGERANYLTRANSFERASE-I INHIBITOR IN HUMAN TUMOR-CELL LINES

      Oncogene
    84. STARK WW; BLASKOVICH MA; JOHNSON BA; VASUDEVAN A; HAMILTON AD; PITT BR; SEBTI SM; DAVIES P
      APOPTOSIS INDUCED IN SMOOTH-MUSCLE CELLS BY GERANYLGERANYL INHIBITIONIS PREVENTED BY SERUM, BUT NOT THROUGH ERK

      The FASEB journal
    85. LERNER EC; HAMILTON AD; SEBTI SM
      INHIBITION OF RAS PHENYLATION - A SIGNALING TARGET FOR NOVEL ANTICANCER DRUG DESIGN

      Anti-cancer drug design
    86. SEBTI SM; HAMILTON AD
      INHIBITION OF RAS PRENYLATION - A NOVEL-APPROACH TO CANCER-CHEMOTHERAPY

      Pharmacology & therapeutics
    87. LIU SH; HAMILTON AD
      CATALYSIS OF PHOSPHODIESTER TRANSESTERIFICATION BY CU(II)-TERPYRIDINECOMPLEXES WITH PERIPHERAL PENDENT BASE GROUPS - IMPLICATIONS FOR THE MECHANISM

      Tetrahedron letters
    88. DAS G; HAMILTON AD
      CARBOHYDRATE-RECOGNITION - ENANTIOSELECTIVE SPIROBIFLUORENE DIPHOSPHONATE RECEPTORS

      Tetrahedron letters
    89. VOGT A; SUN JZ; QIAN YM; HAMILTON AD; SEBTI SM
      THE GERANYLGERANYLTRANSFERASE-I INHIBITOR GGTI-298 ARRESTS HUMAN TUMOR-CELLS IN G(0) G(1) AND INDUCES P21(WAF1/CIP1/SDI1) IN A P53-INDEPENDENT MANNER/

      The Journal of biological chemistry
    90. FINDER JD; LITZ JL; BLASKOVICH MA; MCGUIRE TF; QIAN YM; HAMILTON AD; DAVIES P; SEBTI SM
      INHIBITION OF PROTEIN GERANYLGERANYLATION CAUSES A SUPERINDUCTION OF NITRIC-OXIDE SYNTHASE-2 BY INTERLEUKIN-1-BETA IN VASCULAR SMOOTH-MUSCLE CELLS

      The Journal of biological chemistry
    91. CLARK GJ; KINCH MS; ROGERSGRAHAM K; SEBTI SM; HAMILTON AD; DER CJ
      THE RAS-RELATED PROTEIN RHEB IS FARNESYLATED AND ANTAGONIZES RAS SIGNALING AND TRANSFORMATION

      The Journal of biological chemistry
    92. LINTON B; HAMILTON AD
      FORMATION OF ARTIFICIAL RECEPTORS BY METAL-TEMPLATED SELF-ASSEMBLY

      Chemical reviews
    93. MIQUEL K; PRADINES A; SUN JZ; QIAN YM; HAMILTON AD; SEBTI SM; FAVRE G
      GGTI-298 INDUCES G(0)-G(1) BLOCK AND APOPTOSIS WHEREAS FTI-277 CAUSESG(2)-M ENRICHMENT IN A549 CELLS

      Cancer research
    94. QIAN YM; SEBTI SM; HAMILTON AD
      FARNESYLTRANSFERASE AS A TARGET FOR ANTICANCER DRUG DESIGN

      Biopolymers
    95. HAMURO Y; GEIB SJ; HAMILTON AD
      NOVEL FOLDING PATTERNS IN A FAMILY OF OLIGOANTHRANILAMIDES - NONPEPTIDE OLIGOMERS THAT FORM EXTENDED HELICAL SECONDARY STRUCTURES

      Journal of the American Chemical Society
    96. PECZUH MW; HAMILTON AD; SANCHEZQUESADA J; DEMENDOZA J; HAACK T; GIRALT E
      RECOGNITION AND STABILIZATION OF AN ALPHA-HELICAL PEPTIDE BY A SYNTHETIC RECEPTOR

      Journal of the American Chemical Society
    97. VOGT A; QIAN YM; MCGUIRE TF; HAMILTON AD; SEBTI SM
      PROTEIN GERANYLGERANYLATION, NOT FARNESYLATION, IS REQUIRED FOR THE G(1) TO S-PHASE-TRANSITION IN MOUSE FIBROBLASTS

      Oncogene
    98. SEBTI SM; HAMILTON AD
      RATIONAL DESIGN OF RAS PRENYLTRANSFERASE INHIBITORS AS POTENTIAL ANTICANCER DRUGS

      Biochemical Society transactions
    99. ZAFAR A; YANG J; GEIB SJ; HAMILTON AD
      LINKED BIS-ISOPHTHALIC ACID-DERIVATIVES AS BUILDING-BLOCKS IN THE DESIGN OF SELF-ASSEMBLING STRUCTURES

      Tetrahedron letters
    100. QIAN YM; VOGT A; SEBTI SM; HAMILTON AD
      DESIGN AND SYNTHESIS OF NONPEPTIDE RAS CAAX MIMETICS AS POTENT FARNESYLTRANSFERASE INHIBITORS

      Journal of medicinal chemistry


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Documento generato il 28/10/20 alle ore 12:45:23