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    1. Kwak, MK; Egner, PA; Dolan, PM; Ramos-Gomez, M; Groopman, JD; Itoh, K; Yamamoto, M; Kensler, TW
      Role of phase 2 enzyme induction in chemoprotection by dithiolethiones

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    2. Yoshikawa, H; Matsubara, K; Qian, GS; Jackson, P; Groopman, JD; Manning, JE; Harris, CC; Herman, JG
      SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity

      NATURE GENETICS
    3. Wang, JS; Huang, T; Su, JJ; Liang, F; Wei, ZL; Liang, YQ; Luo, HT; Kuang, SY; Qian, GS; Sun, GJ; He, X; Kensler, TW; Groopman, JD
      Hepatocellular carcinoma and aflatoxin exposure in Zhuqing Village, Fusui County, People's Republic of China

      CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
    4. Walton, M; Egner, P; Scholl, PF; Walker, J; Kensler, TW; Groopman, JD
      Liquid chromatography electrospray-mass spectrometry of urinary aflatoxin biomarkers: Characterization and application to dosimetry and chemoprevention in rats

      CHEMICAL RESEARCH IN TOXICOLOGY
    5. Guengerich, FP; Cai, HL; McMahon, M; Hayes, JD; Sutter, TR; Groopman, JD; Deng, ZW; Harris, TM
      Reduction of aflatoxin B-1 dialdehyde by rat and human aldo-keto reductases

      CHEMICAL RESEARCH IN TOXICOLOGY
    6. Wang, JS; Abubaker, S; He, X; Sun, GJ; Strickland, PT; Groopman, JD
      Development of aflatoxin B-1-lysine adduct monoclonal antibody for human exposure studies

      APPLIED AND ENVIRONMENTAL MICROBIOLOGY
    7. Egner, PA; Wang, JB; Zhu, YR; Zhang, BC; Wu, Y; Zhang, QN; Qian, GS; Kuang, SY; Gange, SJ; Jacobson, LP; Helzlsouer, KJ; Bailey, GS; Groopman, JD; Kensler, TW
      Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals athigh risk for liver cancer

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    8. Jackson, PE; Qian, GS; Friesen, MD; Zhu, YR; Lu, PX; Wang, JB; Wu, YQ; Kensler, TW; Vogelstein, B; Groopman, JD
      Specific p53 mutations detected in plasma and tumors of hepatocellular carcinoma patients by electrospray ionization mass spectrometry

      CANCER RESEARCH
    9. Nelson, CP; Kidd, LCR; Sauvageot, J; Isaacs, WB; De Marzo, AM; Groopman, JD; Nelson, WG; Kensler, TW
      Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1

      CANCER RESEARCH
    10. Jackson, PE; Scholl, PF; Groopman, JD
      Mass spectrometry for genotyping: an emerging tool for molecular medicine

      MOLECULAR MEDICINE TODAY
    11. Weaver, VM; Buckley, T; Groopman, JD
      Lack of specificity of trans,trans-muconic acid as a benzene biomarker after ingestion of sorbic acid-preserved foods

      CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
    12. Carlson, MA; Bargeron, CB; Benson, RC; Fraser, AB; Phillips, TE; Velky, JT; Groopman, JD; Strickland, PT; Ko, HW
      An automated, handheld biosensor for aflatoxin

      BIOSENSORS & BIOELECTRONICS
    13. Stansbury, KH; Noll, DM; Groopman, JD; Trush, MA
      Enzyme-mediated dialdehyde formation: An alternative pathway for benzo[a]pyrene 7,8-dihydrodiol bioactivation

      CHEMICAL RESEARCH IN TOXICOLOGY
    14. Li, Y; Su, JJ; Qin, LL; Egner, PA; Wang, JS; Groopman, JD; Kensler, TW; Roebuck, BD
      Reduction of aflatoxin B-1 adduct biomarkers by oltipraz in the tree shrew(Tupaia belangeri chinensis)

      CANCER LETTERS
    15. Baker, WC; Groopman, JD
      Health of the Bay - Health of People colloquium, November 13, 1998

      ENVIRONMENTAL RESEARCH
    16. Jackson, PE; Groopman, JD
      Aflatoxin and liver cancer

      BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
    17. Wang, JS; Groopman, JD
      DNA damage by mycotoxins

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    18. Kensler, TW; Groopman, JD; Sutter, TR; Curphey, TJ; Roebuck, BD
      Development of cancer chemopreventive agents: Oltipraz as a paradigm

      CHEMICAL RESEARCH IN TOXICOLOGY
    19. Carlson, MA; Bargeron, CB; Benson, RC; Fraser, AB; Groopman, JD; Ko, HW; Phillips, TE; Strickland, PT; Velky, JT
      Development of an automated handheld immunoaffinity fluorometric biosensor

      JOHNS HOPKINS APL TECHNICAL DIGEST
    20. Hoque, A; Patt, YZ; Yoffe, B; Groopman, JD; Greenblatt, MS; Zhang, YJ; Santella, RM
      Does anatoxin B-1 play a role in the etiology of hepatocellular carcinoma in the United States?

      NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
    21. Links, JM; Kensler, TW; Groopman, JD
      Biomarkers in environmental health research & practice

      DRUG AND CHEMICAL TOXICOLOGY
    22. Knight, LP; Primiano, T; Groopman, JD; Kensler, TW; Sutter, TR
      cDNA cloning, expression and activity of a second human aflatoxin B-1-metabolizing member of the aldo-keto reductase superfamily, AKR7A3

      CARCINOGENESIS
    23. Groisman, IJ; Koshy, R; Henkler, F; Groopman, JD; Alaoui-Jamali, MA
      Downregulation of DNA excision repair by the hepatitis B virus-x protein occurs in p53-proficient and p53-deficient cells

      CARCINOGENESIS
    24. Wang, SS; O'Neill, JP; Qian, GS; Zhu, YR; Wang, JB; Armenian, H; Zarba, A; Wang, JS; Kensler, TW; Cariello, NF; Groopman, JD; Swenberg, JA
      Elevated HPRT mutation frequencies in aflatoxin-exposed residents of Daxin, Qidong County, People's Republic of China

      CARCINOGENESIS
    25. Groopman, JD; Kensler, TW
      The light at the end of the tunnel for chemical-specific biomarker: daylight or headlight?

      CARCINOGENESIS
    26. Kinirons, MT; O'Shea, D; Kim, RB; Groopman, JD; Thummel, KE; Wood, JJ; Wilkinson, GR
      Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    27. Rashid, A; Wang, JS; Qian, GS; Lu, BX; Hamilton, SR; Groopman, JD
      Genetic alterations in hepatocellular carcinomas: association between lossof chromosome 4q and p53 gene mutations

      BRITISH JOURNAL OF CANCER
    28. Wang, JS; Shen, XN; He, X; Zhu, YR; Zhang, BC; Wang, JB; Qian, GS; Kuang, SY; Zarba, A; Egner, PA; Jacobson, LP; Munoz, A; Helzlsouer, KJ; Groopman, JD; Kensler, TW
      Protective alterations in phase 1 and 2 metabolism of aflatoxin B-1 by oltipraz in residents of Qidong, People's Republic of China

      JOURNAL OF THE NATIONAL CANCER INSTITUTE
    29. KENSLER TW; GROOPMAN JD; ROEBUCK BD
      USE OF AFLATOXIN ADDUCTS AS INTERMEDIATE END-POINTS TO ASSESS THE EFFICACY OF CHEMOPREVENTIVE INTERVENTIONS IN ANIMALS AND MAN

      Mutation research. Fundamental and molecular mechanisms of mutagenesis
    30. LAKEN SJ; JACKSON PE; KINZLER KW; VOGELSTEIN B; STRICKLAND PT; GROOPMAN JD; FRIESEN MD
      GENOTYPING BY MASS-SPECTROMETRIC ANALYSIS OF SHORT DNA FRAGMENTS

      Nature biotechnology
    31. KENSLER TW; HE X; OTIENO M; EGNER PA; JACOBSON LP; CHEN BB; WANG JS; ZHU YR; ZHANG BC; WANG JB; WU Y; ZHANG QN; QIAN GS; KUANG SY; FANG X; LI YF; YU LY; PROCHASKA HJ; DAVIDSON NE; GORDON GB; GORMAN MB; ZARBA A; ENGER C; MUNOZ A; HELZLSOUER KJ; GROOPMAN JD
      OLTIPRAZ CHEMOPREVENTION TRIAL IN QIDONG, PEOPLES-REPUBLIC-OF-CHINA -MODULATION OF SERUM AFLATOXIN ALBUMIN ADDUCT BIOMARKERS

      Cancer epidemiology, biomarkers & prevention
    32. WEAVER VM; BUCKLEY TJ; GROOPMAN JD
      APPROACHES TO ENVIRONMENTAL EXPOSURE ASSESSMENT IN CHILDREN

      Environmental health perspectives
    33. DEWEESE TL; SHIPMAN JM; LARRIER NA; BUCKLEY NM; KIDD LR; GROOPMAN JD; CUTLER RG; TETIELE H; NELSON WG
      MOUSE EMBRYONIC STEM-CELLS CARRYING ONE OR 2 DEFECTIVE MSH2 ALLELES RESPOND ABNORMALLY TO OXIDATIVE STRESS INFLICTED BY LOW-LEVEL RADIATION

      Proceedings of the National Academy of Sciences of the United Statesof America
    34. KENSLER TW; GANGE SJ; EGNER PA; DOLAN PM; MUNOZ A; GROOPMAN JD; ROGERS AE; ROEBUCK BD
      PREDICTIVE VALUE OF MOLECULAR DOSIMETRY - INDIVIDUAL VERSUS GROUP EFFECTS OF OLTIPRAZ ON AFLATOXIN-ALBUMIN ADDUCTS AND RISK OF LIVER-CANCER

      Cancer epidemiology, biomarkers & prevention
    35. JACOBSON LP; ZHANG BC; ZHU YR; WANG JB; WU Y; ZHANG QN; YU LY; QIAN GS; KUANG SY; LI YF; FANG X; ZARBA A; CHEN BB; ENGER C; DAVIDSON NE; GORMAN MB; GORDON GB; PROCHASKA HJ; EGNER PA; GROOPMAN JD; MUNOZ A; HELZLSOUER KJ; KENSLER TW
      OLTIPRAZ CHEMOPREVENTION TRIAL IN QIDONG, PEOPLES-REPUBLIC-OF-CHINA -STUDY DESIGN AND CLINICAL OUTCOMES

      Cancer epidemiology, biomarkers & prevention
    36. SCHOLL PF; MUSSER SM; GROOPMAN JD
      SYNTHESIS AND CHARACTERIZATION OF AFLATOXIN B-1 MERCAPTURIC ACIDS ANDTHEIR IDENTIFICATION IN RAT URINE

      Chemical research in toxicology
    37. ZHANG BC; ZHU YR; WANG JB; WU Y; ZHANG QN; QIAN GS; KUANG SY; LI YF; FANG X; YU LY; DEFLORA S; JACOBSON LP; ZARBA A; EGNER PA; HE X; WANG JS; CHEN BB; ENGER CL; DAVIDSON NE; GORDON GB; GORMAN MB; PROCHASKA HJ; GROOPMAN JD; MUNOZ A; HELZLSOUER KJ; KENSLER TW
      OLTIPRAZ CHEMOPREVENTION TRIAL IN QIDONG, JIANGSU PROVINCE, PEOPLES-REPUBLIC-OF-CHINA

      Journal of cellular biochemistry
    38. LI Y; YOKOI T; KATSUKI M; WANG JS; GROOPMAN JD; KAMATAKI T
      IN-VIVO ACTIVATION OF AFLATOXIN B-1 IN C57BL 6N MICE CARRYING A HUMANFETUS-SPECIFIC CYP3A7 GENE/

      Cancer research
    39. WANG JS; QIAN GS; ZARBA A; HE X; ZHU YR; ZHANG BC; JACOBSON L; GANGE SJ; MUNOZ A; KENSLER TW; GROOPMAN JD
      TEMPORAL PATTERNS OF AFLATOXIN-ALBUMIN ADDUCTS IN HEPATITIS-B SURFACEANTIGEN-POSITIVE AND ANTIGEN-NEGATIVE RESIDENTS OF DAXIN, QIDONG COUNTY, PEOPLES-REPUBLIC-OF-CHINA

      Cancer epidemiology, biomarkers & prevention
    40. WEAVER VM; DAVOLI CT; MURPHY SE; SUNYER J; HELLER PJ; COLOSIMO SG; GROOPMAN JD
      ENVIRONMENTAL TOBACCO-SMOKE EXPOSURE IN INNER-CITY CHILDREN

      Cancer epidemiology, biomarkers & prevention
    41. GANGE SJ; MUNOZ A; WANG JS; GROOPMAN JD
      VARIABILITY OF MOLECULAR BIOMARKER MEASUREMENTS FROM NONLINEAR CALIBRATION CURVES

      Cancer epidemiology, biomarkers & prevention
    42. KENSLER TW; GROOPMAN JD
      CARCINOGEN-DNA AND PROTEIN ADDUCTS - BIOMARKERS FOR COHORT SELECTION AND MODIFIABLE END-POINTS IN CHEMOPREVENTION TRIALS

      Journal of cellular biochemistry
    43. TRITSCHER AM; SEACAT AM; YAGER JD; GROOPMAN JD; MILLER BD; BELL D; SUTTER TR; LUCIER GW
      INCREASED OXIDATIVE DNA-DAMAGE IN LIVERS OF 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN TREATED INTACT BUT NOT OVARIECTOMIZED RATS

      Cancer letters
    44. SCHOLL P; MUSSER SM; KENSLER TW; GROOPMAN JD
      INHIBITION OF AFLATOXIN M(1) EXCRETION IN RAT URINE DURING DIETARY INTERVENTION WITH OLTIPRAZ

      Carcinogenesis
    45. SOINI Y; CHIA SC; BENNETT WP; GROOPMAN JD; WANG JS; DEBENEDETTI VMG; CAWLEY H; WELSH JA; HANSEN C; BERGASA NV; JONES EA; DIBISCEGLIE AM; TRIVERS GE; SANDOVAL CA; CALDERON IE; ESPINOSA LEM; HARRIS CC
      AN AFLATOXIN-ASSOCIATED MUTATIONAL HOTSPOT AT CODON-249 IN THE P53 TUMOR-SUPPRESSOR GENE OCCURS IN HEPATOCELLULAR CARCINOMAS FROM MEXICO

      Carcinogenesis
    46. WEAVER VM; DAVOLI CT; HELLER PJ; FITZWILLIAM A; PETERS HL; SUNYER J; MURPHY SE; GOLDSTEIN GW; GROOPMAN JD
      BENZENE EXPOSURE, ASSESSED BY URINARY TRANS,TRANS-MUCONIC ACID, IN URBAN CHILDREN WITH ELEVATED BLOOD LEAD LEVELS

      Environmental health perspectives
    47. GROOPMAN JD; WANG JS; SCHOLL P
      MOLECULAR BIOMARKERS FOR AFLATOXINS - FROM ADDUCTS TO GENE-MUTATIONS TO HUMAN LIVER-CANCER

      Canadian journal of physiology and pharmacology
    48. SCHOLL P; MUSSER SM; KENSLER TW; GROOPMAN JD
      MOLECULAR BIOMARKERS FOR AFLATOXINS AND THEIR APPLICATION TO HUMAN LIVER-CANCER

      Pharmacogenetics
    49. SCHOLL PF; MUSSER S; KENSLER TW; GROOPMAN JD
      CHARACTERIZATION OF AFLATOXIN-B1 MERCAPTURATE AS A BIOMARKER OF CHEMOPROTECTION STATUS

      The FASEB journal
    50. GROOPMAN JD; KENSLER TW; LINKS JM
      MOLECULAR EPIDEMIOLOGY AND HUMAN RISK MONITORING

      Toxicology letters
    51. LINKS JM; KENSLER TW; GROOPMAN JD
      BIOMARKERS AND MECHANISTIC APPROACHES IN ENVIRONMENTAL EPIDEMIOLOGY

      Annual review of public health
    52. EGNER PA; GANGE SJ; DOLAN PM; GROOPMAN JD; MUNOZ A; KENSLER TW
      LEVELS OF AFLATOXIN-ALBUMIN BIOMARKERS IN RAT PLASMA ARE MODULATED BYBOTH LONG-TERM AND TRANSIENT INTERVENTIONS WITH OLTIPRAZ

      Carcinogenesis
    53. KANG DH; ROTHMAN N; POIRIER MC; GREENBERG A; HSU CH; SCHWARTZ BS; BASER ME; GROOPMAN JD; WESTON A; STRICKLAND PT
      INTERINDIVIDUAL DIFFERENCES IN THE CONCENTRATION OF 1-HYDROXYPYRENE-GLUCURONIDE IN URINE AND POLYCYCLIC AROMATIC HYDROCARBON-DNA ADDUCTS INPERIPHERAL WHITE BLOOD-CELLS AFTER CHARBROILED BEEF CONSUMPTION

      Carcinogenesis
    54. STRICKLAND PT; GROOPMAN JD
      BIOMARKERS FOR ASSESSING ENVIRONMENTAL EXPOSURE TO CARCINOGENS IN THEDIET

      The American journal of clinical nutrition
    55. WEAVER VM; GROOPMAN JD
      FLUORESCENCE QUANTIFICATION OF AFLATOXIN N-7-GUANINE ADDUCTS

      Cancer epidemiology, biomarkers & prevention
    56. QIAN GS; ROSS RK; YU MC; YUAN JM; GAO YT; HENDERSON BE; WOGAN GN; GROOPMAN JD
      A FOLLOW-UP-STUDY OF URINARY MARKERS OF AFLATOXIN EXPOSURE AND LIVER-CANCER RISK IN SHANGHAI, PEOPLES-REPUBLIC-OF-CHINA

      Cancer epidemiology, biomarkers & prevention
    57. BAILEY GS; LOVELAND PM; PEREIRA C; PIERCE D; HENDRICKS JD; GROOPMAN JD
      QUANTITATIVE CARCINOGENESIS AND DOSIMETRY IN RAINBOW-TROUT FOR AFLATOXIN-B-1 AND AFLATOXICOL, 2 AFLATOXINS THAT FORM THE SAME DNA ADDUCT

      Mutation research. Section on environmental mutagenesis and related subjects
    58. STRICKLAND PT; KANG D; BOWMAN ED; FITZWILLIAM A; DOWNING TE; ROTHMAN N; GROOPMAN JD; WESTON A
      IDENTIFICATION OF 1-HYDROXYPYRENE GLUCURONIDE AS A MAJOR PYRENE METABOLITE IN HUMAN URINE BY SYNCHRONOUS FLUORESCENCE SPECTROSCOPY AND GAS-CHROMATOGRAPHY MASS-SPECTROMETRY

      Carcinogenesis
    59. RALL DP; GROOPMAN JD
      WORKSHOP-C - THE AMBIENT ENVIRONMENT - MONITORING EFFECTS AND INITIATING CHANGE

      Preventive medicine
    60. JAKAB GJ; HMIELESKI RR; ZARBA A; HEMENWAY DR; GROOPMAN JD
      RESPIRATORY AFLATOXICOSIS - SUPPRESSION OF PULMONARY AND SYSTEMIC HOST DEFENSES IN RATS AND MICE

      Toxicology and applied pharmacology
    61. GROOPMAN JD; WOGAN GN; ROEBUCK BD; KENSLER TW
      MOLECULAR BIOMARKERS FOR AFLATOXINS AND THEIR APPLICATION TO HUMAN CANCER PREVENTION

      Cancer research
    62. GROOPMAN JD; KENSLER TW
      MOLECULAR BIOMARKERS FOR HUMAN CHEMICAL CARCINOGEN EXPOSURES

      Chemical research in toxicology
    63. STYCZYNSKI PB; BLACKMON RC; GROOPMAN JD; KENSLER TW
      THE DIRECT GLUCURONIDATION OF 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE (PHIP) BY HUMAN AND RABBIT LIVER-MICROSOMES

      Chemical research in toxicology
    64. OGORMAN MA; SCHOLL PF; GROOPMAN JD; YAGER JD
      ELEVATION OF 8-HYDROXY-2'-DEOXYGUANOSINE IN FEMALE RAT-LIVER AND CULTURED RAT HEPATOCYTE DNA FOLLOWING TREATMENT WITH ETHINYL ESTRADIOL

      Hepatology
    65. SHEABAR FZ; GROOPMAN JD; QIAN GS; WOGAN GN
      QUANTITATIVE-ANALYSIS OF AFLATOXIN ALBUMIN ADDUCTS

      Carcinogenesis
    66. GROOPMAN JD; WILD CP; HASLER J; CHEN JS; WOGAN GN; KENSLER TW
      MOLECULAR EPIDEMIOLOGY OF AFLATOXIN EXPOSURES - VALIDATION OF AFLATOXIN-N7-GUANINE LEVELS IN URINE AS A BIOMARKER IN EXPERIMENTAL RAT MODELS AND HUMANS

      Environmental health perspectives
    67. PFEIFER AMA; COLE KE; SMOOT DT; WESTON A; GROOPMAN JD; SHIELDS PG; VIGNAUD JM; JUILLERAT M; LIPSKY MM; TRUMP BF; LECHNER JF; HARRIS CC
      SIMIAN VIRUS-40 LARGE TUMOR ANTIGEN-IMMORTALIZED NORMAL HUMAN LIVER EPITHELIAL-CELLS EXPRESS HEPATOCYTE CHARACTERISTICS AND METABOLIZE CHEMICAL CARCINOGENS

      Proceedings of the National Academy of Sciences of the United Statesof America
    68. KINIRONS MT; OSHEA D; DOWNING TE; FITZWILLIAM AT; JOELLENBECK L; GROOPMAN JD; WILKINSON GR; WOOD AJJ
      ABSENCE OF CORRELATIONS AMONG 3 PUTATIVE IN-VIVO PROBES OF HUMAN CYTOCHROME-P4503A ACTIVITY IN YOUNG HEALTHY-MEN

      Clinical pharmacology and therapeutics
    69. BOLTON MG; MUNOZ A; JACOBSON LP; GROOPMAN JD; MAXUITENKO YY; ROEBUCK BD; KENSLER TW
      TRANSIENT INTERVENTION WITH OLTIPRAZ PROTECTS AGAINST AFLATOXIN-INDUCED HEPATIC TUMORIGENESIS

      Cancer research
    70. RANEY KD; SHIMADA T; KIM DH; GROOPMAN JD; HARRIS TM; GUENGERICH FP
      OXIDATION OF AFLATOXINS AND STERIGMATOCYSTIN BY HUMAN LIVER-MICROSOMES - SIGNIFICANCE OF AFLATOXIN-Q1 AS A DETOXICATION PRODUCT OF AFLATOXIN-B1

      Chemical research in toxicology


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Documento generato il 24/10/20 alle ore 20:10:19