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    1. Heck, R; Henderson, AP; Kohler, B; Retey, J; Golding, BT
      Crossed acyloin condensation of aliphatic aldehydes

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
    2. Smith, PG; Thomas, HD; Barlow, HC; Griffin, RJ; Golding, BT; Calvert, AH; Newell, DR; Curtin, NJ
      In vitro and in vivo properties of novel nucleoside transport inhibitors with improved pharmacological properties that potentiate antifolate activity

      CLINICAL CANCER RESEARCH
    3. Stockley, M; Clegg, W; Fontana, G; Golding, BT; Martin, N; Rigoreau, LJM; Smith, GCM; Griffin, RJ
      Synthesis, crystal structure determination, and biological properties of the DNA-dependent protein kinase (DNA-PK) inhibitor 3-cyano-6-hydrazonomethyl-5-(4-pyridyl)pyrid-[1H]-2-one (OK-1035)

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    4. Cottrell, L; Golding, BT; Munter, T; Watson, WP
      In vitro metabolism of chloroprene: Species differences, epoxide stereochemistry and a de-chlorination pathway

      CHEMICAL RESEARCH IN TOXICOLOGY
    5. Watson, WP; Cottrell, L; Zhang, DP; Golding, BT
      Metabolism and molecular toxicology of isoprene

      CHEMICO-BIOLOGICAL INTERACTIONS
    6. Smith, DM; Golding, BT; Radom, L
      Understanding the mechanism of B-12-dependent diol dehydratase: A synergistic retro-push-pull proposal

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    7. Wetmore, SD; Smith, DM; Golding, BT; Radom, L
      Interconversion of (S)-glutamate and (2S,3S)-3-methylaspartate: A distinctive B-12-dependent carbon-skeleton rearrangement

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    8. Anderson, RJ; Ashwell, S; Garnett, I; Golding, BT
      Intramolecular functionalisation by a methylene radical of a 1,2-diol and a vicinal amino alcohol: models for coenzyme B-12-dependent diol dehydratase and ethanolamine ammonia lyase

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    9. Klotz, B; Barnes, I; Golding, BT; Becker, KH
      Atmospheric chemistry of toluene-1,2-oxide/2-methyloxepin

      PCCP PHYSICAL CHEMISTRY CHEMICAL PHYSICS
    10. Zhang, DP; Bleasdale, C; Golding, BT; Watson, WP
      Synthesis of enantiopure isoprene epoxides from (S)-lactic acid via 'dispoke' intermediates

      CHEMICAL COMMUNICATIONS
    11. Barlow, HC; Bowman, KJ; Curtin, NJ; Calvert, AH; Golding, BT; Huang, B; Loughlin, PJ; Newell, DR; Smith, PG; Griffin, RJ
      Resistance-modifying agents. Part 7: 2, 6-disubstituted-4,8-dibenzylaminopyrimido[5,4-d]pyrimidines that inhibit nucleoside transport in the presenceof alpha(1)-acid glycoprotein (AGP)

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    12. Haglund, J; Rafiq, A; Ehrenberg, L; Golding, BT; Tornqvist, M
      Transalkylation of phosphotriesters using cob(I)alamin: Toward specific determination of DNA-phosphate adducts

      CHEMICAL RESEARCH IN TOXICOLOGY
    13. Wang, MF; Golding, BT; Potter, GA
      A convenient preparation of p-metboxybenzyl esters

      SYNTHETIC COMMUNICATIONS
    14. Griffin, RJ; Arris, CE; Bleasdale, C; Boyle, FT; Calvert, AH; Curtin, NJ; Dalby, C; Kanugula, S; Lembicz, NK; Newell, DR; Pegg, AE; Golding, BT
      Resistance-modifying agents. 8. Inhibition of O-6-alkylguanine-DNA alkyltransferase by O-6-alkenyl-, O-6-cycloalkenyl-, and O-6-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O-6-(1-cyclopentenylmethyl)guanine

      JOURNAL OF MEDICINAL CHEMISTRY
    15. White, AW; Almassy, R; Calvert, AH; Curtin, NJ; Griffin, RJ; Hostomsky, Z; Maegley, K; Newell, DR; Srinivasan, S; Golding, BT
      Resistance-modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase

      JOURNAL OF MEDICINAL CHEMISTRY
    16. Arris, CE; Boyle, FT; Calvert, AH; Curtin, NJ; Endicott, JA; Garman, EF; Gibson, AE; Golding, BT; Grant, S; Griffin, RJ; Jewsbury, P; Johnson, LN; Lawrie, AM; Newell, DR; Noble, MEM; Sausville, EA; Schultz, R; Yu, W
      Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles

      JOURNAL OF MEDICINAL CHEMISTRY
    17. Ciceri, D; Pierik, AJ; Hartrampf, G; Broker, G; Speranza, G; Buckel, W; Cornforth, J; Golding, BT
      Stereochemistry of the methyl group in (R)-3-methylitaconate derived by rearrangement of 2-methylideneglutarate catalysed by a coenzyme B-12-dependent mutase

      HELVETICA CHIMICA ACTA
    18. Kitching, MS; Clegg, W; Elsegood, MRJ; Griffin, RJ; Golding, BT
      Synthesis of 3-alkoxy- and 3-alkylamino-2-alkyl-3-arylisoindolinones

      SYNLETT
    19. Golding, BT; Mitchinson, A; Clegg, W; Elsegood, MRJ; Griffin, RJ
      Protecting-group strategies for the synthesis of N-4-substituted and N-1,N-8-disubstituted spermidines, exemplified by hirudonine

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    20. Curtin, NJ; Bowman, KJ; Turner, RN; Huang, B; Loughlin, PJ; Calvert, AH; Golding, BT; Griffin, RJ; Newell, DR
      Potentiation of the cytotoxicity of thymidylate synthase (TS) inhibitors by dipyridamole analogues with reduced alpha(1)-acid glycoprotein binding

      BRITISH JOURNAL OF CANCER
    21. Smith, DM; Golding, BT; Radom, L
      Facilitation of enzyme-catalyzed reactions by partial proton transfer: Application to coenzyme-B-12-dependent methylmalonyl-CoA mutase

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    22. Smith, DM; Golding, BT; Radom, L
      On the mechanism of action of vitamin B-12: Theoretical studies of the 2-methyleneglutarate mutase catalyzed rearrangement

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    23. Smith, DM; Golding, BT; Radom, L
      Understanding the mechanism of B-12-dependent methylmalonyl-CoA mutase: Partial proton transfer in action

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    24. Smith, DM; Golding, BT; Radom, L
      Toward a consistent mechanism for diol dehydratase catalyzed reactions: Anapplication of the partial-proton-transfer concept

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    25. Scott, AP; Golding, BT; Radom, L
      Remarkable cleavage of molecular hydrogen without the use of metallic catalysts: a theoretical investigation

      NEW JOURNAL OF CHEMISTRY
    26. ALMASSY R; BOWMAN K; CALVERT AH; CURTIN NJ; GOLDING BT; HOSTOMSKA Z; HOSTOMSKY Z; GRIFFIN RJ; MAEGLEY K; NEWELL DR; SRINIVASAN S; WHITE AW; WEBBER S
      2-PHENYLBENZIMIDAZOLE-4-CARBOXAMIDES ARE POTENT INHIBITORS OF THE DNA-REPAIR ENZYME POLY(ADP-RIBOSE)-POLYMERASE (PARP)

      Annals of oncology
    27. GRANT S; BOYLE F; CALVERT AH; CURTIN NJ; ENDICOTT J; GOLDING BT; GRIFFIN RJ; JOHNSON LN; NEWELL DR; NOBLE MEM; ROBSON C
      O-6-ALKYLGUANINES AS SELECTIVE INHIBITORS OF CYCLIN-DEPENDENT KINASES

      Annals of oncology
    28. LINDSTROM AB; YEOWELLOCONNELL K; WAIDYANATHA S; MCDONALD TA; GOLDING BT; RAPPAPORT SM
      FORMATION OF HEMOGLOBIN AND ALBUMIN ADDUCTS OF BENZENE OXIDE IN MOUSE, RAT, AND HUMAN BLOOD

      Chemical research in toxicology
    29. TILBY MJ; MCCARTNEY H; GOULD KA; OHARE CC; HARTLEY JA; HALL AG; GOLDING BT; LAWLEY PD
      A MONOFUNCTIONAL DERIVATIVE OF MELPHALAN - PREPARATION, DNA ALKYLATION PRODUCTS, AND DETERMINATION OF THE SPECIFICITY OF MONOCLONAL-ANTIBODIES THAT RECOGNIZE MELPHALAN-DNA ADDUCTS

      Chemical research in toxicology
    30. Richardson, KA; Peters, MMCG; Megens, RHJJJ; van Elburg, PA; Golding, BT; Boogaard, PJ; Watson, WP; van Sittert, NJ
      Identification of novel metabolites of butadiene monoepoxide in rats and mice

      CHEMICAL RESEARCH IN TOXICOLOGY
    31. Buckel, W; Golding, BT
      Radical species in the catalytic pathways of enzymes from anaerobes

      FEMS MICROBIOLOGY REVIEWS
    32. TAREKE E; GOLDING BT; SMALL RD; TORNQVIST M
      HEMOGLOBIN ADDUCTS FROM ISOPRENE AND ISOPRENE MONOEPOXIDES

      Xenobiotica
    33. Griffin, RJ; Srinivasan, S; Bowman, K; Calvert, AH; Curtin, NJ; Newell, DR; Pemberton, LC; Golding, BT
      Resistance-modifying agents. 5. Synthesis and biological properties of quinazolinone inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase (PARP)

      JOURNAL OF MEDICINAL CHEMISTRY
    34. BOWMAN KJ; WHITE A; GOLDING BT; GRIFFIN RJ; CURTIN NJ
      POTENTIATION OF ANTICANCER AGENT CYTOTOXICITY BY THE POTENT POLY(ADP-RIBOSE) POLYMERASE INHIBITORS NU1025 AND NU1064

      British Journal of Cancer
    35. BOTHE H; DARLEY DJ; ALBRACHT SPJ; GERFEN GJ; GOLDING BT; BUCKEL W
      IDENTIFICATION OF THE 4-GLUTAMYL RADICAL AS AN INTERMEDIATE IN THE CARBON SKELETON REARRANGEMENT CATALYZED BY COENZYME B-12-DEPENDENT GLUTAMATE MUTASE FROM CLOSTRIDIUM-COCHLEARIUM

      Biochemistry
    36. SMITH DM; NICOLAIDES A; GOLDING BT; RADOM L
      RING-OPENING OF THE CYCLOPROPYLCARBINYL RADICAL AND ITS N-SUBSTITUTEDAND O-SUBSTITUTED ANALOGS - A THEORETICAL-EXAMINATION OF VERY FAST UNIMOLECULAR REACTIONS

      Journal of the American Chemical Society
    37. KLOTZ B; BARNES I; BECKER KH; GOLDING BT
      ATMOSPHERIC CHEMISTRY OF BENZENE OXIDE OXEPIN

      Journal of the Chemical Society. Faraday transactions
    38. BLEASDALE C; CAMERON R; EDWARDS C; GOLDING BT
      DIMETHYLDIOXIRANE CONVERTS BENZENE OXIDE OXEPIN INTO (Z,Z)-MUCONALDEHYDE AND SYM-OXEPIN OXIDE - MODELING THE METABOLISM OF BENZENE AND ITS PHOTOOXIDATIVE DEGRADATION/

      Chemical research in toxicology
    39. LEMBICZ NK; GRANT S; CLEGG W; GRIFFIN RJ; HEATH SL; GOLDING BT
      FACILITATION OF DISPLACEMENTS AT THE 6-POSITION OF PURINES BY THE USEOF 1,4-DIAZABICYCLO[2.2.2]OCTANE AS LEAVING GROUP

      Journal of the Chemical Society. Perkin transactions. I
    40. LEMBICZ NK; GRANT S; CLEGG W; GRIFFIN RJ; HEATH SL; GOLDING BT
      FACILITATION OF DISPLACEMENTS AT THE 6-POSITION OF PURINES BY THE USEOF 1,4-DIAZABICYCLO[2.2.2]OCTANE AS LEAVING GROUP (VOL 1, PG 185, 1997)

      Journal of the Chemical Society. Perkin transactions. I
    41. HENDERSON AP; RISEBOROUGH J; BLEASDALE C; CLEGG W; ELSEGOOD MRJ; GOLDING BT
      4,4'-DIMETHOXYTRITYL AND 4,4',4''-TRIMETHAXYTRITYL AS PROTECTING GROUPS FOR AMINO FUNCTIONS - SELECTIVITY FOR PRIMARY AMINO-GROUPS AND APPLICATION IN N-15-LABELING

      Journal of the Chemical Society. Perkin transactions. I
    42. LINDSTROM AB; YEOWELLOCONNELL K; WAIDYANATHA S; GOLDING BT; TORNEROVELEZ R; RAPPAPORT SM
      MEASUREMENT OF BENZENE OXIDE IN THE BLOOD OF RATS FOLLOWING ADMINISTRATION OF BENZENE

      Carcinogenesis
    43. SMALL RD; GOLDING BT; WATSON WP
      SPECIES-DIFFERENCES IN THE STEREOCHEMISTRY OF THE METABOLISM OF ISOPRENE IN-VITRO

      Xenobiotica
    44. BROWN JM; GOLDING BT; BARTON DHR
      PREFACE - AN APPRECIATION OF BIRCH,ARTHUR, 1915-1995

      Tetrahedron
    45. GOLDING BT; BLEASDALE C; MCGINNIS J; MULLER S; REES HT; REES NH; FARMER PB; WATSON WP
      THE MECHANISM OF DECOMPOSITION OF N-METHYL-N-NITROSOUREA (MNU) IN WATER AND A STUDY OF ITS REACTIONS WITH 2'-DEOXYGUANOSINE, 2'-DEOXYGUANOSINE 5'-MONOPHOSPHATE AND D(GTGCAC)

      Tetrahedron
    46. GOLDING BT; SLAICH PK; KENNEDY G; BLEASDALE C; WATSON WP
      MECHANISMS OF FORMATION OF ADDUCTS FROM REACTIONS OF GLYCIDALDEHYDE WITH 2'-DEOXYGUANOSINE AND OR GUANOSINE/

      Chemical research in toxicology
    47. BUCKEL W; GOLDING BT
      GLUTAMATE AND 2-METHYLENEGLUTARATE MUTASE - FROM MICROBIAL CURIOSITIES TO PARADIGMS FOR COENZYME B-12-DEPENDENT ENZYMES

      Chemical Society reviews
    48. BLEASDALE C; SMALL RD; WATSON WP; WILSON J; GOLDING BT
      STUDIES ON THE MOLECULAR TOXICOLOGY OF BUTA-1,3-DIENE AND ISOPRENE EPOXIDES

      Toxicology
    49. BLEASDALE C; KENNEDY G; MACGREGOR JO; NIESCHALK J; PEARCE K; WATSON WP; GOLDING BT
      CHEMISTRY OF MUCONALDEHYDES OF POSSIBLE RELEVANCE TO THE TOXICOLOGY OF BENZENE

      Environmental health perspectives
    50. KENNEDY G; SLAICH PK; GOLDING BT; WATSON WP
      STRUCTURE AND MECHANISM OF FORMATION OF A NEW ADDUCT FROM FORMALDEHYDE AND GUANOSINE

      Chemico-biological interactions
    51. EDWARDS CH; GOLDING BT; KROLL F; BEATRIX B; BROKER G; BUCKEL W
      ROTATION OF THE EXO-METHYLENE GROUP OF 2-METHYLENEGLUTARATE CATALYZEDBY COENZYME-B-12-DEPENDENT 2-METHYLENEGLUTARATE MUTASE FROM CLOSTRIDIUM-BARKERI

      Journal of the American Chemical Society
    52. KOHLER B; KNAUER M; CLEGG W; ELSEGOOD MRJ; GOLDING BT; RETEY J
      PERIPHERALLY SUBSTITUTED COBALOXIMES - X-RAY CRYSTAL-STRUCTURE ANALYSIS OF ORPHOLINO)OCTANE-4,5-DIOXIMATO]PYRIDINECOBALT(III)

      Angewandte Chemie, International Edition in English
    53. BEATRIX B; ZELDER O; KROLL FK; ORLYGASSON G; GOLDING BT; BUCKEL W
      EVIDENCE FOR A MECHANISM INVOLVING TRANSIENT FRAGMENTATION IN CARBON SKELETON REARRANGEMENTS DEPENDENT ON COENZYME B-12

      Angewandte Chemie, International Edition in English
    54. GRAFFIN RJ; CURTIN NJ; NEWELL DR; GOLDING BT; DURKACZ BW; CALVERT AH
      THE ROLE OF INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE AS RESISTANCE-MODIFYING AGENTS IN CANCER-THERAPY

      Biochimie
    55. GRIFFIN RJ; PEMBERTON LC; RHODES D; BLEASDALE C; BOWMAN K; CALVERT AH; CURTIN NJ; DURKACZ BW; NEWELL DR; PORTEOUS JK; GOLDING BT
      NOVEL POTENT INHIBITORS OF THE DNA-REPAIR ENZYME POLY(ADP-RIBOSE)POLYMERASE (PARP)

      Anti-cancer drug design
    56. CLEGG W; GOLDING BT; KING BJ; MAUDE AB
      4 ISOMERIC DIOXOLANE DERIVATIVES OF D-CAMPHORQUINONE

      Acta crystallographica. Section C, Crystal structure communications
    57. BOULTON S; PEMBERTON LC; PORTEOUS JK; CURTIN NJ; GRIFFIN RJ; GOLDING BT; DURKACZ BW
      POTENTIATION OF TEMOZOLOMIDE-INDUCED CYTOTOXICITY - A COMPARATIVE-STUDY OF THE BIOLOGICAL EFFECTS OF POLY(ADP-RIBOSE) POLYMERASE INHIBITORS

      British Journal of Cancer
    58. BLEASDALE C; GOLDING BT; KITSON SL
      PREPARATION OF ETHENYL AND OXIRANOL CARBAMATE AND THEIR (2-H-2(2))-DERIVATIVES USING SELENIUM CHEMISTRY - THERMOLYSIS OF OXIRANOL CARBAMATEAND REACTION WITH ADENOSINE

      Bioorganic & medicinal chemistry letters
    59. BLEASDALE C; ELLWOOD SB; GOLDING BT; SLAICH PK; TAYLOR OJ; WATSON WP
      SYNTHESIS OF [N-15]GUANOSINES AND DEOXY[N-15]GUANOSINES FROM NO-1-(BETA-D-RIBOFURANOSYL)IMIDAZOLE-4-CARBOXAMIDE (AICA-RIBOSIDE)

      Journal of the Chemical Society. Perkin transactions. I
    60. GOLDING BT; GRIFFIN RJ; MITCHINSON A; OSULLIVAN MC
      NEW ROUTES TO POLYAMINE ANALOGS

      Biochemical Society transactions
    61. ARRIS CE; BLEASDALE C; CALVERT AH; CURTIN NJ; DALBY C; GOLDING BT; GRIFFIN RJ; LUNN JM; MAJOR GN; NEWELL DR
      PROBING THE ACTIVE-SITE AND MECHANISM OF ACTION OF O-6-METHYLGUANINE-DNA METHYLTRANSFERASE WITH SUBSTRATE-ANALOGS TO (O-6-SUBSTITUTED GUANINES)

      Anti-cancer drug design
    62. MITCHINSON A; GOLDING BT; GRIFFIN RJ; OSULLIVAN MC
      DISCRIMINATION OF SPERMIDINE AMINO FUNCTIONS BY A NEW PROTECTING GROUP STRATEGY APPLICATION TO THE SYNTHESIS OF GUANIDINYLATED POLYAMINES, INCLUDING HIRUDONINE

      Journal of the Chemical Society, Chemical Communications
    63. BLEASDALE C; GOLDING BT; LEE WH; MASKILL H; RISEBOROUGH J; SMITS E
      THE MECHANISM OF DEAMINATION OF METHOXY SUBSTITUTED TRITYLAMMONIUM IONS IN METHANOLIC AQUEOUS ACID

      Journal of the Chemical Society, Chemical Communications
    64. WATSON WP; BLEASDALE C; GOLDING BT
      CHEMICALS AND CANCER - ESTIMATING THE RISK

      Chemistry in Britain
    65. WATSON WP; BLEASDALE C; GOLDING BT
      CHEMICALS AND CANCER - ESTIMATING THE RISK (VOL 30, PG 661, 1994)

      Chemistry in Britain
    66. ANGUS PM; GOLDING BT; JURISSON SS; SARGESON AM; WILLIS AC
      INTRAMOLECULAR CONDENSATION-REACTIONS OF S-METHYLMETHIONINE COORDINATED TO COBALT(III)

      Australian Journal of Chemistry
    67. BLEASDALE C; GOLDING BT; KENNEDY G; MACGREGOR JO; WATSON WP
      REACTIONS OF MUCONALDEHYDE ISOMERS WITH NUCLEOPHILES INCLUDING TRI-O-ACETYLGUANOSINE - FORMATION OF 1,2-DISUBSTITUTED PYRROLES FROM REACTIONS OF THE (Z,Z)-ISOMER WITH PRIMARY AMINES

      Chemical research in toxicology
    68. DALBY C; BLEASDALE C; CLEGG W; ELSEGOOD MRJ; GOLDING BT; GRIFFIN RJ
      REGIOSPECIFIC ALKYLATION OF 6-CHLOROPURINE AND 2,6-DICHLOROPURINE AT N7 BY TRANSIENT PROTECTION OF N3 N9 BY METHYLCOBALOXIME/

      Angewandte Chemie, International Edition in English
    69. BLEASDALE C; ELLIS MK; FARMER PB; GOLDING BT; HANDLEY KF; JONES P; MCFARLANE W
      SYNTHESIS AND SPECTROSCOPIC CHARACTERIZATION OF PERBENZOIC-ACID-O-17,O-18,NITROSOBENZENE-O-17,O-18 AND NITROSOBENZENE-N-15

      Journal of labelled compounds & radiopharmaceuticals
    70. GOLDING BT; GRIFFIN AL; ROBINSON DH
      SYNTHESIS OF A REVERSE ESTER ANALOG OF 1,2-SN-DIGLYCERIDES FROM (S)-1,2-DI-O-ISOPROPYLIDENEGLYCEROL - EFFICIENT, STEREOSPECIFIC NUCLEOPHILIC DISPLACEMENT VIA A TRIFLATE AT GLYCEROL C-2

      Tetrahedron letters
    71. ANGUS PM; GOLDING BT; SARGESON AM
      A SIMPLE SYNTHESIS OF THE RIPENING AGENT 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID

      Journal of the Chemical Society, Chemical Communications
    72. ANDERSON RJ; GOLDING BT; HUGHES NA
      SYNTHESIS OF SOME SUGAR COBALOXIMES AND A TRIFLUOROACETIC ACID-INDUCED FRAGMENTATION

      Carbohydrate research


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Documento generato il 10/08/20 alle ore 05:20:07