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La ricerca find articoli where authors phrase all words ' GERMAIN RN' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 78 riferimenti
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    1. Dorfman, JR; Stefanova, I; Yasutomo, K; Germain, RN
      Class II essential for CD4 survival - Response

      NATURE IMMUNOLOGY
    2. Delon, J; Kaibuchi, K; Germain, RN
      Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin

      IMMUNITY
    3. Delon, J; Germain, RN
      The immunological synapse: required for T cell receptor signalling or directing T cell effector function? Response

      CURRENT BIOLOGY
    4. Germain, RN
      The art of the probable: System control in the adaptive immune system

      SCIENCE
    5. Germain, RN
      The T cell receptor for antigen: Signaling and ligand discrimination

      JOURNAL OF BIOLOGICAL CHEMISTRY
    6. Castellino, F; Han, R; Germain, RN
      The transmembrane segment of invariant chain mediates binding to MHC classII molecules in a CLIP-independent manner

      EUROPEAN JOURNAL OF IMMUNOLOGY
    7. Dorfman, JR; Stefanova, I; Yasutomo, K; Germain, RN
      CD4(+) T cell survival is not directly linked to self-MHC-induced TCR signaling

      NATURE IMMUNOLOGY
    8. Lu, FWM; Yasutomo, K; Goodman, GB; McHeyzer-Williams, LJ; McHeyzer-Williams, MG; Germain, RN; Ashwell, JD
      Thymocyte resistance to glucocorticoids leads to antigen-specific unresponsiveness due to "holes" in the T cell repertoire

      IMMUNITY
    9. Delon, J; Germain, RN
      Information transfer at the immunological synapse

      CURRENT BIOLOGY
    10. Yasutomo, K; Doyle, C; Miele, L; Fuchs, C; Germain, RN
      The duration of antigen receptor signalling determines CD4(+) versus CD8(+) T-cell lineage fate (vol 404, pg 506, 2000)

      NATURE
    11. Yasutomo, K; Doyle, C; Miele, L; Germain, RN
      The duration of antigen receptor signalling determines CD4(+) versus CD8(+) T-cell lineage fate

      NATURE
    12. Yasutomo, K; Lucas, B; Germain, RN
      TCR signaling for initiation and completion of thymocyte positive selection has distinct requirements for ligand quality and presenting cell type

      JOURNAL OF IMMUNOLOGY
    13. Lucas, B; Germain, RN
      Opening a window on thymic positive selection: Developmental changes in the influence of cosignaling by integrins and CD28 on selection events induced by TCR engagement

      JOURNAL OF IMMUNOLOGY
    14. Inaba, K; Turley, S; Iyoda, T; Yamaide, F; Shimoyama, S; Sousa, CRE; Germain, RN; Mellman, I; Steinman, RM
      The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli

      JOURNAL OF EXPERIMENTAL MEDICINE
    15. Castellino, F; Boucher, PE; Eichelberg, K; Mayhew, M; Rothman, JE; Houghton, AN; Germain, RN
      Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways

      JOURNAL OF EXPERIMENTAL MEDICINE
    16. Dittel, BN; Stefanova, I; Germain, RN; Janeway, CA
      Cross-antagonism of a T cell clone expressing two distinct T cell receptors

      IMMUNITY
    17. Lucas, B; Stefanova, I; Yasutomo, K; Dautigny, N; Germain, RN
      Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire

      IMMUNITY
    18. Germain, RN; Stefanova, I
      The dynamics of T cell receptor signaling: Complex orchestration and the key roles of tempo and cooperation

      ANNUAL REVIEW OF IMMUNOLOGY
    19. Itoh, Y; Hemmer, B; Martin, R; Germain, RN
      Serial TCR engagement and down-modulation by peptide : MHC molecule ligands: Relationship to the quality of individual TCR signaling events

      JOURNAL OF IMMUNOLOGY
    20. Sousa, CRE; Germain, RN
      Analysis of adjuvant function by direct visualization of antigen presentation in vivo: Endotoxin promotes accumulation of antigen-bearing dendritic cells in the T cell areas of lymphoid tissue

      JOURNAL OF IMMUNOLOGY
    21. SANTANGELO DB; LUCAS B; WATERBURY PG; COHEN B; BRABB T; GOVERMAN J; GERMAIN RN; JANEWAY CA
      A MOLECULAR MAP OF T-CELL DEVELOPMENT

      Immunity (Cambridge, Mass.)
    22. SANTANGELO DB; LUCAS B; WATERBURY G; COHEN B; BRABB T; GOVERMAN J; GERMAIN RN; JANEWAY CA
      A DEVELOPMENTAL MAP OF THYMOCYTE SELECTION

      The FASEB journal
    23. NATARAJAN K; CASTELLINO F; GERMAIN RN; MARGULIES DH
      THE ZEBRAFISH INVARIANT CHAIN ASSEMBLES WITH MURINE I-A(D)

      The FASEB journal
    24. CASTELLINO F; ZAPPACOSTA F; COLIGAN JE; GERMAIN RN
      LARGE PROTEIN-FRAGMENTS AS SUBSTRATES FOR ENDOCYTIC ANTIGEN CAPTURE BY MHC CLASS-II MOLECULES

      The Journal of immunology (1950)
    25. HEMMER B; STEFANOVA I; VERGELLI M; GERMAIN RN; MARTIN R
      RELATIONSHIPS AMONG TCR LIGAND POTENCY, THRESHOLDS FOR EFFECTOR FUNCTION ELICITATION, AND THE QUALITY OF EARLY SIGNALING EVENTS IN HUMAN T-CELLS

      The Journal of immunology
    26. KIM MG; CHEN C; FLOMERFELT FA; GERMAIN RN; SCHWARTZ RH
      A SUBTRACTIVE PCR-BASED CDNA LIBRARY MADE FROM FETAL THYMIC STROMAL CELLS

      Journal of immunological methods
    27. PORGADOR A; IRVINE KR; IWASAKI A; BARBER BH; RESTIFO NP; GERMAIN RN
      PREDOMINANT ROLE FOR DIRECTLY TRANSFECTED DENDRITIC CELLS IN ANTIGEN PRESENTATION TO CD8(+)T CELLS AFTER GENE GUN IMMUNIZATION

      The Journal of experimental medicine
    28. COMBADIERE B; SOUSA CRE; GERMAIN RN; LENARDO MJ
      SELECTIVE INDUCTION OF APOPTOSIS IN MATURE T-LYMPHOCYTES BY VARIANT T-CELL RECEPTOR LIGANDS

      The Journal of experimental medicine
    29. PORGADOR A; YEWDELL JW; DENG YP; BENNINK JR; GERMAIN RN
      LOCALIZATION, QUANTITATION, AND IN-SITU DETECTION OF SPECIFIC PEPTIDEMHC CLASS-I COMPLEXES USING A MONOCLONAL-ANTIBODY

      Immunity
    30. GERMAIN RN
      T-CELL SIGNALING - THE IMPORTANCE OF RECEPTOR CLUSTERING

      Current biology
    31. CASTELLINO F; ZHONG GM; GERMAIN RN
      ANTIGEN PRESENTATION BY MHC CLASS-II MOLECULES - INVARIANT CHAIN FUNCTION, PROTEIN TRAFFICKING, AND THE MOLECULAR-BASIS OF DIVERSE DETERMINANT CAPTURE

      Human immunology
    32. PORGADOR A; GERMAIN RN
      MONOCLONAL-ANTIBODY DETECTION OF SPECIFIC CELL-BOUND PEPTIDE-MHC CLASS-I COMPLEXES WITH A SENSITIVITY APPROACHING CD8-CELLS( T)

      Journal of allergy and clinical immunology
    33. ITOH Y; GERMAIN RN
      CELL RESPONSE THRESHOLD AND RESPONSE HIERARCHY ANALYZED AT THE SINGLE-CELL LEVEL

      Journal of allergy and clinical immunology
    34. MARTIN R; STEPHANOVA I; VERGELLI M; GERMAIN RN; HEMMER B
      COMPARISON OF EFFECTOR FUNCTIONS AND EARLY SIGNALING EVENTS IN HUMAN CD4-CELLS( T)

      Journal of allergy and clinical immunology
    35. CASTELLINO F; ZAPPACOSTA F; GERMAIN RN
      IDENTIFICATION OF LARGE PROTEIN-FRAGMENTS AS A SUBSTRATE FOR ANTIGEN CAPTURE BY MHC CLASS-II MOLECULES

      Journal of allergy and clinical immunology
    36. ZHONG GM; SOUSA CRE; GERMAIN RN
      PRODUCTION, SPECIFICITY, AND FUNCTIONALITY OF MONOCLONAL-ANTIBODIES TO SPECIFIC PEPTIDE-MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II COMPLEXESFORMED BY PROCESSING OF EXOGENOUS PROTEIN

      Proceedings of the National Academy of Sciences of the United Statesof America
    37. DAY PM; YEWDELL JW; PORGADOR A; GERMAIN RN; BENNINK JR
      DIRECT DELIVERY OF EXOGENOUS MHC CLASS-I MOLECULE-BINDING OLIGOPEPTIDES TO THE ENDOPLASMIC-RETICULUM OF VIABLE CELLS

      Proceedings of the National Academy of Sciences of the United Statesof America
    38. ZHONG GM; SOUSA CRE; GERMAIN RN
      ANTIGEN-UNSPECIFIC B-CELLS AND LYMPHOID DENDRITIC CELLS BOTH SHOW EXTENSIVE SURFACE EXPRESSION OF PROCESSED ANTIGEN-MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II COMPLEXES AFTER SOLUBLE-PROTEIN EXPOSURE IN-VIVO ORIN-VITRO

      The Journal of experimental medicine
    39. ITOH Y; GERMAIN RN
      SINGLE-CELL ANALYSIS REVEALS REGULATED HIERARCHICAL T-CELL ANTIGEN RECEPTOR SIGNALING THRESHOLDS AND INTRACLONAL HETEROGENEITY FOR INDIVIDUAL CYTOKINE RESPONSES OF CD4(-CELLS() T)

      The Journal of experimental medicine
    40. SOUSA CRE; HIENY S; SCHARTONKERSTEN T; JANKOVIC D; CHAREST H; GERMAIN RN; SHER A
      IN-VIVO MICROBIAL STIMULATION INDUCES RAPID CD40 LIGAND-INDEPENDENT PRODUCTION OF INTERLEUKIN-12 BY DENDRITIC CELLS AND THEIR REDISTRIBUTION TO T-CELL AREAS

      The Journal of experimental medicine
    41. VANMEERWIJK JPM; MARGUERAT S; LEES RK; GERMAIN RN; FOWLKES BJ; MACDONALD HR
      QUANTITATIVE IMPACT OF THYMIC CLONAL DELETION ON THE T-CELL REPERTOIRE

      The Journal of experimental medicine
    42. ZHONG GM; ROMAGNOLI P; GERMAIN RN
      RELATED LEUCINE-BASED CYTOPLASMIC TARGETING SIGNALS IN INVARIANT CHAIN AND MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II MOLECULES CONTROL ENDOCYTIC PRESENTATION OF DISTINCT DETERMINANTS IN A SINGLE PROTEIN

      The Journal of experimental medicine
    43. MADRENAS J; CHAU LA; SMITH J; BLUESTONE JA; GERMAIN RN
      THE EFFICIENCY OF CD4 RECRUITMENT TO LIGAND-ENGAGED TCR CONTROLS THE AGONIST PARTIAL AGONIST PROPERTIES OF PEPTIDE-MHC MOLECULE LIGANDS/

      The Journal of experimental medicine
    44. LUCAS B; GERMAIN RN
      UNEXPECTEDLY COMPLEX REGULATION OF CD4 CD8 CORECEPTOR EXPRESSION SUPPORTS A REVISED MODEL FOR CD4(+)CD8(+) THYMOCYTE DIFFERENTIATION/

      Immunity
    45. LUCAS B; GERMAIN RN
      T-CELL REPERTOIRE - POLITICAL CORRECTNESS IN THE IMMUNE-SYSTEM

      Current biology
    46. HUANG LY; VANMEERWIJK JPM; BIKOFF EK; GERMAIN RN
      COMPARISON OF THYMOCYTE DEVELOPMENT IN NORMAL AND INVARIANT CHAIN-DEFICIENT MICE PROVIDES EVIDENCE THAT MATURATION-RELATED CHANGES IN TCR AND CORECEPTOR LEVELS PLAY A CRITICAL ROLE IN CELL FATE

      International immunology
    47. GERMAIN RN; CASTELLINO F; HAN RC; SOUSA CR; ROMAGNOLI P; SADEGHNASSERI S; ZHONG GM
      PROCESSING AND PRESENTATION OF ENDOCYTICALLY ACQUIRED PROTEIN ANTIGENS BY MHC CLASS-II AND CLASS-I MOLECULES

      Immunological reviews
    48. MADRENAS J; SCHWARTZ RH; GERMAIN RN
      INTERLEUKIN-2 PRODUCTION, NOT THE PATTERN OF EARLY T-CELL ANTIGEN RECEPTOR-DEPENDENT TYROSINE PHOSPHORYLATION, CONTROLS ANERGY INDUCTION BYBOTH AGONISTS AND PARTIAL AGONISTS

      Proceedings of the National Academy of Sciences of the United Statesof America
    49. SHEN XL; HU B; MCPHIE P; WU XH; FOX A; GERMAIN RN; KONIG R
      PEPTIDES CORRESPONDING TO CD4-INTERACTING REGIONS OF MURINE MWC CLASS-II MOLECULES MODULATE IMMUNE-RESPONSES OF CD4(-LYMPHOCYTES IN-VITRO AND IN-VIVO() T)

      The Journal of immunology
    50. ZHONG GM; CASTELLINO F; ROMAGNOLI P; GERMAIN RN
      EVIDENCE THAT BINDING-SITE OCCUPANCY IS NECESSARY AND SUFFICIENT FOR EFFECTIVE MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS-II TRANSPORT THROUGH THE SECRETORY PATHWAY REDEFINES THE PRIMARY FUNCTION OF CLASS II-ASSOCIATED INVARIANT CHAIN PEPTIDES (CLIP)

      The Journal of experimental medicine
    51. SOUSA CRE; LEVINE EH; GERMAIN RN
      PARTIAL SIGNALING BY CD8(-CELLS IN RESPONSE TO ANTAGONIST LIGANDS() T)

      The Journal of experimental medicine
    52. BIKOFF EK; GERMAIN RN; ROBERTSON EJ
      ALLELIC DIFFERENCES AFFECTING INVARIANT CHAIN DEPENDENCY OF MHC CLASS-II SUBUNIT ASSEMBLY

      Immunity
    53. CASTELLINO F; GERMAIN RN
      EXTENSIVE TRAFFICKING OF MHC CLASS II-INVARIANT CHAIN COMPLEXES IN THE ENDOCYTIC PATHWAY AND APPEARANCE OF PEPTIDE-LOADED CLASS-II IN MULTIPLE COMPARTMENTS

      Immunity
    54. MADRENAS J; SCHWARTZ RH; GERMAIN RN
      T-CELL ANERGY IS NOT DETERMINED BY THE PATTERN OF EARLY TCR SIGNALS

      Journal of the American Society of Nephrology
    55. GERMAIN RN; CASTELLINO F; ROMAGNOLI P; MADRENAS J; WANGE R; ISAKOV N; SAMELSON LE
      FORMATION AND FUNCTION OF PEPTIDE - MHC MOLECULE LIGANDS FOR THE TCR

      Journal of cellular biochemistry
    56. MADRENAS J; WANGE RL; WANG JL; ISAKOV N; SAMELSON LE; GERMAIN RN
      ZETA-PHOSPHORYLATION WITHOUT ZAP-70 ACTIVATION-INDUCED BY TCR ANTAGONISTS OR PARTIAL AGONISTS

      Science
    57. VANMEERWIJK JPM; OCONNELL EM; GERMAIN RN
      EVIDENCE FOR LINEAGE COMMITMENT AND INITIATION OF POSITIVE SELECTION BY THYMOCYTES WITH INTERMEDIATE SURFACE PHENOTYPES

      The Journal of immunology
    58. ROMAGNOLI P; GERMAIN RN
      INHIBITION OF INVARIANT CHAIN-(II)-CALNEXIN INTERACTION RESULTS IN ENHANCED DEGRADATION OF II BUT DOES NOT PREVENT THE ASSEMBLY OF ALPHA-BETA-II COMPLEXES

      The Journal of experimental medicine
    59. KONIG R; SHEN XL; GERMAIN RN
      INVOLVEMENT OF BOTH MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II ALPHA-CHAINS AND BETA-CHAINS IN CD4 FUNCTION INDICATES A ROLE FOR ORDERED OLIGOMERIZATION IN T-CELL ACTIVATION

      The Journal of experimental medicine
    60. SOUSA CRE; GERMAIN RN
      MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I PRESENTATION OF PEPTIDES DERIVED FROM SOLUBLE EXOGENOUS ANTIGEN BY A SUBSET OF CELLS ENGAGED IN PHAGOCYTOSIS

      The Journal of experimental medicine
    61. MARKS MS; GERMAIN RN; BONIFACINO JS
      TRANSIENT AGGREGATION OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II CHAINS DURING ASSEMBLY IN NORMAL SPLEEN-CELLS

      The Journal of biological chemistry
    62. GERMAIN RN; CASTELLINO F; RINKER AG; SADEGHNASSERI S; ROMAGNOLI P
      THE BIOCHEMISTRY AND CELL BIOLOGY OF MHC CLASS-II ANTIGEN PRESENTATION

      Journal of cellular biochemistry
    63. BONNEROT C; MARKS MS; COSSON P; ROBERTSON EJ; BIKOFF EK; GERMAIN RN; BONIFACINO JS
      ASSOCIATION WITH BIP AND AGGREGATION OF CLASS-II MCH MOLECULES SYNTHESIZED IN THE ABSENCE OF INVARIANT CHAIN

      EMBO journal
    64. GERMAIN RN
      MHC-DEPENDENT ANTIGEN-PROCESSING AND PEPTIDE PRESENTATION - PROVIDINGLIGANDS FOR T-LYMPHOCYTE ACTIVATION

      Cell
    65. SADEGHNASSERI S; STERN LJ; WILEY DC; GERMAIN RN
      MHC CLASS-II FUNCTION PRESERVED BY LOW-AFFINITY PEPTIDE INTERACTIONS PRECEDING STABLE BINDING

      Nature
    66. JARVIS CD; GERMAIN RN; HAGER GL; DAMSCHRODER M; MATIS LA
      TISSUE-SPECIFIC EXPRESSION OF MESSENGER-RNAS ENCODING ENDOGENOUS VIRAL SUPERANTIGENS

      The Journal of immunology
    67. ROMAGNOLI P; GERMAIN RN
      THE CLIP REGION OF INVARIANT CHAIN PLAYS A CRITICAL ROLE IN REGULATING MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II FOLDING, TRANSPORT, AND PEPTIDE OCCUPANCY

      The Journal of experimental medicine
    68. SEDER RA; GERMAIN RN; LINSLEY PS; PAUL WE
      CD28-MEDIATED COSTIMULATION OF INTERLEUKIN-2 (IL-2) PRODUCTION PLAYS A CRITICAL ROLE IN T-CELL PRIMING FOR IL-4 AND INTERFERON-GAMMA PRODUCTION

      The Journal of experimental medicine
    69. GERMAIN RN
      SEEING DOUBLE

      Current biology
    70. BERZOFSKY JA; SHIRAI M; NAKAGAWA Y; PENDLETON CD; HOUGHTEN RA; YOKOMURO K; GERMAIN RN; TAKAHASHI H
      PROMISCUITY FOR MHC AND INDUCTION OF BROAD CROSS-REACTIVITY FOR HIV-1ISOLATES OF A DOMINANT CTL DETERMINANT OF THE HIV-1 ENVELOPE

      Journal of acquired immune deficiency syndromes
    71. GERMAIN RN
      PEPTIDE BINDING, CONFORMATIONAL-CHANGES, AND INTRACELLULAR-TRANSPORT IN THE MHC CLASS-I AND CLASS-II PRESENTATION PATHWAYS

      Journal of acquired immune deficiency syndromes
    72. HAHN WC; MENZIN E; SAITO T; GERMAIN RN; BIERER BE
      THE COMPLETE SEQUENCES OF PLASMIDS PFNEO AND PMH-NEO - CONVENIENT EXPRESSION VECTORS FOR HIGH-LEVEL EXPRESSION OF EUKARYOTIC GENES IN HEMATOPOIETIC-CELL LINES

      Gene
    73. VANMEERWIJK JPM; GERMAIN RN
      DEVELOPMENT OF MATURE CD8- SELECTION RATHER THAN INSTRUCTION( THYMOCYTES )

      Science
    74. GERMAIN RN; RINKER AG
      PEPTIDE BINDING INHIBITS PROTEIN AGGREGATION OF INVARIANT-CHAIN FREE CLASS-II DIMERS AND PROMOTES SURFACE EXPRESSION OF OCCUPIED MOLECULES

      Nature
    75. DING L; LINSLEY PS; HUANG LY; GERMAIN RN; SHEVACH EM
      IL-10 INHIBITS MACROPHAGE COSTIMULATORY ACTIVITY BY SELECTIVELY INHIBITING THE UP-REGULATION OF B7 EXPRESSION

      The Journal of immunology
    76. DING L; LINSLEY PS; HUANG LY; GERMAIN RN; SHEVACH EM
      IL-10 INHIBITS MACROPHAGE (M0) COSTIMULATORY ACTIVITY BY SELECTIVELY INHIBITING THE UP-REGULATION OF B7 EXPRESSION

      The Journal of immunology
    77. SEDER RA; GERMAIN RN; LINSLEY PS; PAUL WE
      PRIMING FOR LYMPHOKINE PRODUCTION CAN BE ACHIEVED IN THE ABSENCE OF B7 CD28 CO-STIMULATION IF IL-2 IS PRESENT/

      The Journal of immunology
    78. BIKOFF EK; HUANG LY; EPISKOPOU V; VANMEERWIJK J; GERMAIN RN; ROBERTSON EJ
      DEFECTIVE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II ASSEMBLY, TRANSPORT, PEPTIDE ACQUISITION, AND CD4-CELL SELECTION IN MICE LACKING INVARIANT CHAIN EXPRESSION( T)

      The Journal of experimental medicine


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Documento generato il 22/01/21 alle ore 05:42:21