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    1. Spiegelman, BM; Flier, JS
      Obesity and the regulation of energy balance

      CELL
    2. Masuzaki, H; Paterson, J; Shinyama, H; Morton, NM; Mullins, JJ; Seckl, JR; Flier, JS
      A transgenic model of visceral obesity and the metabolic syndrome

      SCIENCE
    3. Ruderman, N; Flier, JS
      Cell biology - Chewing the fat - ACC and energy balance

      SCIENCE
    4. Flier, JS
      Diabetes - The missing link with obesity?

      NATURE
    5. Ludwig, DS; Tritos, NA; Mastaitis, JW; Kulkarni, R; Kokkotou, E; Elmquist, J; Lowell, B; Flier, JS; Maratos-Flier, E
      Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

      JOURNAL OF CLINICAL INVESTIGATION
    6. Harris, M; Aschkenasi, C; Elias, CF; Chandrankunnel, A; Nillni, EA; Bjorbaek, C; Elmquist, JK; Flier, JS; Hollenberg, AN
      Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling

      JOURNAL OF CLINICAL INVESTIGATION
    7. Mantzoros, CS; Ozata, M; Negrao, AB; Suchard, MA; Ziotopoulou, M; Caglayan, S; Elashoff, RM; Cogswell, RJ; Negro, P; Liberty, V; Wong, ML; Veldhuis, J; Ozdemir, IC; Gold, PW; Flier, JS; Licinio, J
      Synchronicity of frequently sampled thyrotropin (TSH) and leptin concentrations in healthy adults and leptin-deficient subjects: Evidence for possible partial TSH regulation by leptin in humans

      JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
    8. Bjorbaek, C; Buchholz, RM; Davis, SM; Bates, SH; Pierroz, DD; Gu, H; Neel, BG; Myers, MG; Flier, JS
      Divergent roles of SHP-2 in ERK activation by leptin receptors

      JOURNAL OF BIOLOGICAL CHEMISTRY
    9. Flier, JS
      Pushing the envelope on lipodystrophy

      NATURE GENETICS
    10. Ahima, RS; Flier, JS
      Adipose tissue as an endocrine organ

      TRENDS IN ENDOCRINOLOGY AND METABOLISM
    11. Ziotopoulou, M; Mantzoros, CS; Hileman, SM; Flier, JS
      Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice

      AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
    12. Ahima, RS; Saper, CB; Flier, JS; Elmquist, JK
      Leptin regulation of neuroendocrine systems

      FRONTIERS IN NEUROENDOCRINOLOGY
    13. Ahima, RS; Flier, JS
      Leptin

      ANNUAL REVIEW OF PHYSIOLOGY
    14. Kahn, BB; Flier, JS
      Obesity and insulin resistance

      JOURNAL OF CLINICAL INVESTIGATION
    15. Flier, JS; Harris, M; Hollenberg, AN
      Leptin, nutrition, and the thyroid: the why, the wherefore, and the wiring

      JOURNAL OF CLINICAL INVESTIGATION
    16. El-Haschimi, K; Pierroz, DD; Hileman, SM; Bjorbaek, C; Flier, JS
      Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

      JOURNAL OF CLINICAL INVESTIGATION
    17. Hileman, SM; Pierroz, DD; Flier, JS
      Leptin, nutrition, and reproduction: Timing is everything

      JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
    18. Mantzoros, CS; Flier, JS
      Editorial: Leptin as a therapeutic agent - Trials and tribulations

      JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
    19. Bjorbaek, C; Lavery, HJ; Bates, SH; Olson, RK; Davis, SM; Flier, JS; Myers, MG
      SOCS3 mediates feedback inhibition of the leptin receptor via Tyr(985)

      JOURNAL OF BIOLOGICAL CHEMISTRY
    20. Nillni, EA; Vaslet, C; Harris, M; Hollenberg, A; Bjorbaek, C; Flier, JS
      Leptin regulates prothyrotropin-releasing hormone biosynthesis - Evidence for direct and indirect pathways

      JOURNAL OF BIOLOGICAL CHEMISTRY
    21. Kim, YB; Uotani, S; Pierrez, DD; Flier, JS; Kahn, BB
      In vivo administration of leptin activates signal transduction directly ininsulin-sensitive tissues: Overlapping but distinct pathways from insulin

      ENDOCRINOLOGY
    22. Hileman, SM; Tornoe, J; Flier, JS; Bjorbaek, C
      Transcellular transport of leptin by the short leptin receptor isoform ObRa in Madin-Darby Canine Kidney cells

      ENDOCRINOLOGY
    23. Flier, JS
      Big deal about a little insulin

      NATURE MEDICINE
    24. Elias, CF; Aschkenasi, C; Lee, C; Kelly, J; Ahima, RS; Bjorbaek, C; Flier, JS; Saper, CB; Elmquist, JK
      Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area

      NEURON
    25. Flier, JS; Hollenberg, AN
      ADD-1 provides major new insight into the mechanism of insulin action

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    26. Bjorbaek, C; El-Haschimi, K; Frantz, JD; Flier, JS
      The role of SOCS-3 in leptin signaling and leptin resistance

      JOURNAL OF BIOLOGICAL CHEMISTRY
    27. Ahima, RS; Bjorbaek, C; Osei, S; Flier, JS
      Regulation of neuronal and glial proteins by leptin: Implications for brain development

      ENDOCRINOLOGY
    28. Bjorbaek, C; Elmquist, JK; El-Haschimi, K; Kelly, J; Ahima, RS; Hileman, S; Flier, JS
      Activation of SOCS-3 messenger ribonucleic acid in the hypothalamus by ciliary neurotrophic factor

      ENDOCRINOLOGY
    29. Ahima, RS; Kelly, J; Elmquist, JK; Flier, JS
      Distinct physiologic and neuronal responses to decreased leptin and mild hyperleptinemia

      ENDOCRINOLOGY
    30. Uotani, S; Bjorbaek, C; Tornoe, J; Flier, JS
      Functional properties of leptin receptor isoforms internalization and degradation of leptin and ligand-induced receptor downregulation

      DIABETES
    31. Cittadini, A; Mantzoros, CS; Hampton, TG; Travers, KE; Katz, SE; Morgan, JP; Flier, JS; Douglas, PS
      Cardiovascular abnormalities in transgenic mice with reduced brown fat - An animal model of human obesity

      CIRCULATION
    32. ELMQUIST JK; MARATOSFLIER E; SAPER CB; FLIER JS
      UNRAVELING THE CENTRAL-NERVOUS-SYSTEM PATHWAYS UNDERLYING RESPONSES TO LEPTIN

      Nature neuroscience
    33. BJORBAEK C; ELMQUIST JK; FRANTZ JD; SHOELSON SE; FLIER JS
      IDENTIFICATION OF SOCS-3 AS A POTENTIAL MEDIATOR OF CENTRAL LEPTIN RESISTANCE

      MOLECULAR CELL
    34. LICINIO J; NEGRAO AB; MANTZOROS C; KAKLAMANI V; WONG ML; BONGIORNO PB; MULLA A; CEARNAL L; VELDHUIS JD; FLIER JS; MCCANN SM; GOLD PW
      SYNCHRONICITY OF FREQUENTLY-SAMPLED 24-HOUR CONCENTRATIONS OF CIRCULATING LEPTIN, LUTEINIZING-HORMONE, AND ESTRADIOL IN HEALTHY WOMEN

      Journal of investigative medicine
    35. FLIER JS
      LOWERED LEPTIN SLIMS IMMUNE-RESPONSE

      Nature medicine
    36. MANTZOROS CS; LIOLIOS AD; TRITOS NA; KAKLAMANI VG; DOULGERAKIS DE; GRIVEAS I; MOSES AC; FLIER JS
      CIRCULATING INSULIN CONCENTRATIONS, SMOKING, AND ALCOHOL INTAKE ARE IMPORTANT INDEPENDENT PREDICTORS OF LEPTIN IN YOUNG HEALTHY-MEN

      Obesity research
    37. RICE JW; KANDASAMY R; HAMMOND C; BJORBAEK C; FLIER JS; STANCATO LF
      CROSS-TALK BETWEEN THE JAK STAT AND MAPK SIGNAL-TRANSDUCTION PATHWAYSIN LEPTIN SIGNALING/

      Molecular biology of the cell
    38. ROEMMICH JN; CLARK PA; BERR SS; MAI V; MANTZOROS CS; FLIER JS; WELTMAN A; ROGOL AD
      GENDER DIFFERENCES IN LEPTIN LEVELS DURING PUBERTY ARE RELATED TO THESUBCUTANEOUS FAT DEPOT AND SEX STEROIDS

      American journal of physiology: endocrinology and metabolism
    39. LUDWIG DS; MOUNTJOY KG; TATRO JB; GILLETTE JA; FREDERICH RC; FLIER JS; MARATOSFLIER E
      MELANIN-CONCENTRATING HORMONE - A FUNCTIONAL MELANOCORTIN ANTAGONIST IN THE HYPOTHALAMUS

      American journal of physiology: endocrinology and metabolism
    40. FLIER JS; MARATOSFLIER E
      OBESITY AND THE HYPOTHALAMUS - NOVEL PEPTIDES FOR NEW PATHWAYS

      Cell
    41. HAMANN A; FLIER JS; LOWELL BB
      OBESITY AFTER GENETIC ABLATION OF BROWN ADIPOSE-TISSUE

      Zeitschrift fur Ernahrungswissenschaft
    42. LEGRADI G; EMERSON CH; AHIMA RS; RAND WM; FLIER JS; LECHAN RM
      ARCUATE NUCLEUS ABLATION PREVENTS RESTING-INDUCED SUPPRESSION OF PROTRH MESSENGER-RNA IN THE HYPOTHALAMIC PARAVENTRICULAR NUCLEUS

      Neuroendocrinology
    43. LICINIO J; NEGRAO AB; MANTZOROS C; KAKLAMANI V; WONG ML; BONGIORNO PB; MULLA A; CEARNAL L; VELDHUIS JD; FLIER JS; MCCANN SM; GOLD PW
      SYNCHRONICITY OF FREQUENTLY SAMPLED, 24-H CONCENTRATIONS OF CIRCULATING LEPTIN, LUTEINIZING-HORMONE, AND ESTRADIOL IN HEALTHY WOMEN

      Proceedings of the National Academy of Sciences of the United Statesof America
    44. ELMQUIST JK; AHIMA RS; ELIAS CF; FLIER JS; SAPER CB
      LEPTIN ACTIVATES DISTINCT PROJECTIONS FROM THE DORSOMEDIAL AND VENTROMEDIAL HYPOTHALAMIC NUCLEI

      Proceedings of the National Academy of Sciences of the United Statesof America
    45. ELMQUIST JK; BJORBAEK C; AHIMA RS; FLIER JS; SAPER CB
      DISTRIBUTIONS OF LEPTIN RECEPTOR MESSENGER-RNA ISOFORMS IN THE RAT-BRAIN

      Journal of comparative neurology
    46. AHIMA RS; PRABAKARAN D; FLIER JS
      POSTNATAL LEPTIN SURGE AND REGULATION OF CIRCADIAN-RHYTHM OF LEPTIN BY FEEDING - IMPLICATIONS FOR ENERGY HOMEOSTASIS AND NEUROENDOCRINE FUNCTION

      The Journal of clinical investigation
    47. FLIER JS
      WHATS IN A NAME - IN SEARCH OF LEPTINS PHYSIOLOGICAL-ROLE

      The Journal of clinical endocrinology and metabolism
    48. LICINIO J; NEGRAO AB; MANTZOROS C; KAKLAMANI V; WONG ML; BONGIORNO PB; NEGRO PP; MULLA A; VELDHUIS JD; CEARNAL L; FLIER JS; GOLD PW
      SEX-DIFFERENCES IN CIRCULATING HUMAN LEPTIN PULSE AMPLITUDE - CLINICAL IMPLICATIONS

      The Journal of clinical endocrinology and metabolism
    49. DASILVA BA; BJORBAEK C; UOTANI S; FLIER JS
      FUNCTIONAL-PROPERTIES OF LEPTIN RECEPTOR ISOFORMS CONTAINING THE GLN-]PRO EXTRACELLULAR DOMAIN MUTATION OF THE FATTY RAT

      Endocrinology
    50. BJORBAEK C; ELMQUIST JK; MICHL P; AHIMA RS; VANBUEREN A; MCCALL AL; FLIER JS
      EXPRESSION OF LEPTIN RECEPTOR ISOFORMS IN RAT-BRAIN MICROVESSELS

      Endocrinology
    51. TRITOS NA; ELMQUIST JK; MASTAITIS JW; FLIER JS; MARATOSFLIER E
      CHARACTERIZATION OF EXPRESSION OF HYPOTHALAMIC APPETITE-REGULATING PEPTIDES IN OBESE HYPERLEPTINEMIC BROWN ADIPOSE TISSUE-DEFICIENT (UNCOUPLING PROTEIN-PROMOTER-DRIVEN DIPHTHERIA-TOXIN-A) MICE

      Endocrinology
    52. MANTZOROS CS; FREDERICH RC; QU D; LOWELL BB; MARATOSFLIER E; FLIER JS
      SEVERE LEPTIN RESISTANCE IN BROWN FAT-DEFICIENT UNCOUPLING PROTEIN PROMOTER-DRIVEN DIPHTHERIA-TOXIN-A MICE DESPITE SUPPRESSION OF HYPOTHALAMIC NEUROPEPTIDE-Y AND CIRCULATING CORTICOSTERONE CONCENTRATIONS. (VOL47, PG 230, 1998)

      Diabetes
    53. MANTZOROS CS; FREDERICH RC; QU DQ; LOWELL BB; MARATOSFLIER E; FLIER JS
      SEVERE LEPTIN RESISTANCE IN BROWN FAT-DEFICIENT UNCOUPLING PROTEIN PROMOTER-DRIVEN DIPHTHERIA-TOXIN-A MICE DESPITE SUPPRESSION OF HYPOTHALAMIC NEUROPEPTIDE-Y AND CIRCULATING CORTICOSTERONE CONCENTRATIONS

      Diabetes
    54. UOTANI S; BJORBAEK C; FLIER JS
      LONG AND SHORT LEPTIN RECEPTOR ISOFORMS MEDIATE INTERNALIZATION AND DEGRADATION OF LEPTIN/

      Diabetes
    55. KIM YB; UOTANI S; FLIER JS; KAHN BB
      IN-VIVO ADMINISTRATION OF LEPTIN RAPIDLY ACTIVATES PHOSPHOINOSITIDE 3-KINASE (PI3-KINASE) IN INSULIN-SENSITIVE TISSUES

      Diabetes
    56. FLIER JS; ELMQUIST JK
      ENERGETIC PURSUIT OF LEPTIN FUNCTION

      Nature biotechnology
    57. LICINIO J; MANTZOROS C; NEGRAO AB; CIZZA G; WONG ML; BONGIORNO PB; CHROUSOS GP; KARP B; ALLEN C; FLIER JS; GOLD PW
      HUMAN LEPTIN LEVELS ARE PULSATILE AND INVERSELY RELATED TO PITUITARY-ADRENAL-FUNCTION

      Nature medicine
    58. FLIER JS; LOWELL BB
      OBESITY RESEARCH SPRINGS A PROTON LEAK

      Nature genetics
    59. ERICKSON JC; AHIMA RS; HOLLOPETER G; FLIER JS; PALMITER RD
      ENDOCRINE FUNCTION OF NEUROPEPTIDE-Y KNOCKOUT MICE

      Regulatory peptides
    60. LOWELL BB; FLIER JS
      BROWN ADIPOSE-TISSUE, BETA-3-ADRENERGIC RECEPTORS, AND OBESITY

      Annual review of medicine
    61. LEROITH D; KING G; FLIER JS
      INSULIN-LIKE GROWTH-FACTORS

      The New England journal of medicine
    62. FLIER JS
      LEPTIN EXPRESSION AND ACTION - NEW EXPERIMENTAL PARADIGMS

      Proceedings of the National Academy of Sciences of the United Statesof America
    63. SARRAF P; FREDERICH RC; TURNER EM; MA G; JASKOWIAK NT; RIVET DJ; FLIER JS; LOWELL BB; FRAKER DL; ALEXANDER HR
      MULTIPLE CYTOKINES AND ACUTE-INFLAMMATION RAISE MOUSE LEPTIN LEVELS -POTENTIAL ROLE IN INFLAMMATORY ANOREXIA

      The Journal of experimental medicine
    64. AHIMA RS; DUSHAY J; FLIER SN; PRABAKARAN D; FLIER JS
      LEPTIN ACCELERATES THE ONSET OF PUBERTY IN NORMAL FEMALE MICE

      The Journal of clinical investigation
    65. VIDALPUIG AJ; CONSIDINE RV; JIMENEZLINAN M; WERMAN A; PORIES WJ; CARO JF; FLIER JS
      PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GENE-EXPRESSION IN HUMAN TISSUES - EFFECTS OF OBESITY, WEIGHT-LOSS, AND REGULATION BY INSULIN AND GLUCOCORTICOIDS

      The Journal of clinical investigation
    66. MANTZOROS CS; VARVARIGOU A; KAKLAMANI VG; BERATIS NG; FLIER JS
      EFFECT OF BIRTH-WEIGHT AND MATERNAL SMOKING ON CORD-BLOOD LEPTIN CONCENTRATIONS OF FULL-TERM AND PRETERM NEWBORNS

      The Journal of clinical endocrinology and metabolism
    67. MANTZOROS CS; DUNAIF A; FLIER JS
      LEPTIN CONCENTRATIONS IN THE POLYCYSTIC-OVARY-SYNDROME

      The Journal of clinical endocrinology and metabolism
    68. MANTZOROS C; FLIER JS; LESEM MD; BREWERTON TD; JIMERSON DC
      CEREBROSPINAL-FLUID LEPTIN IN ANOREXIA-NERVOSA - CORRELATION WITH NUTRITIONAL-STATUS AND POTENTIAL ROLE IN RESISTANCE TO WEIGHT-GAIN

      The Journal of clinical endocrinology and metabolism
    69. MANTZOROS CS; FLIER JS; ROGOL AD
      A LONGITUDINAL ASSESSMENT OF HORMONAL AND PHYSICAL ALTERATIONS DURINGNORMAL PUBERTY IN BOYS .5. RISING LEPTIN LEVELS MAY SIGNAL THE ONSET OF PUBERTY

      The Journal of clinical endocrinology and metabolism
    70. MANTZOROS CS; ROSEN HN; GREENSPAN SL; FLIER JS; MOSES AC
      SHORT-TERM HYPERTHYROIDISM HAS NO EFFECT ON LEPTIN LEVELS IN MAN

      The Journal of clinical endocrinology and metabolism
    71. MANTZOROS CS; MOSCHOS S; AVRAMOPOULOS I; KAKLAMANI V; LIOLIOS A; DOULGERAKIS DE; GRIVEAS I; KATSILAMBROS N; FLIER JS
      LEPTIN CONCENTRATIONS IN RELATION TO BODY-MASS INDEX AND THE TUMOR-NECROSIS-FACTOR-ALPHA SYSTEM IN HUMANS

      The Journal of clinical endocrinology and metabolism
    72. BJORBAEK C; UOTANI S; DASILVA B; FLIER JS
      DIVERGENT SIGNALING CAPACITIES OF THE LONG AND SHORT ISOFORMS OF THE LEPTIN RECEPTOR

      The Journal of biological chemistry
    73. SOLANES G; VIDALPUIG A; GRUJIC D; FLIER JS; LOWELL BB
      THE HUMAN UNCOUPLING PROTEIN-3 GENE - GENOMIC STRUCTURE, CHROMOSOMAL LOCALIZATION, AND GENETIC-BASIS FOR SHORT AND LONG FORM TRANSCRIPTS

      The Journal of biological chemistry
    74. WERMAN A; HOLLENBERG A; SOLANES G; BJORBAEK C; VIDALPUIG AJ; FLIER JS
      LIGAND-INDEPENDENT ACTIVATION DOMAIN IN THE N-TERMINUS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA (PPAR-GAMMA) - DIFFERENTIAL ACTIVITY OF PPAR-GAMMA-1 AND PPAR-GAMMA-2 ISOFORMS AND INFLUENCE OF INSULIN

      The Journal of biological chemistry
    75. HEIMAN ML; AHIMA RS; CRAFT LS; SCHONER B; STEPHENS TW; FLIER JS
      LEPTIN INHIBITION OF THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS IN RESPONSE TO STRESS

      Endocrinology
    76. LEGRADI G; EMERSON CH; AHIMA RS; FLIER JS; LECHAN RM
      LEPTIN PREVENTS FASTING-INDUCED SUPPRESSION OF PROTHYROTROPIN-RELEASING HORMONE MESSENGER-RIBONUCLEIC-ACID IN NEURONS OF THE HYPOTHALAMIC PARAVENTRICULAR NUCLEUS

      Endocrinology
    77. CINTI S; FREDERICH RC; ZINGARETTI MC; DEMATTEIS R; FLIER JS; LOWELL BB
      IMMUNOHISTOCHEMICAL LOCALIZATION OF LEPTIN AND UNCOUPLING PROTEIN IN WHITE AND BROWN ADIPOSE-TISSUE

      Endocrinology
    78. ELMQUIST JK; AHIMA RS; MARATOSFLIER E; FLIER JS; SAFER CB
      LEPTIN ACTIVATES NEURONS IN VENTROBASAL HYPOTHALAMUS AND BRAIN-STEM

      Endocrinology
    79. CITTADINI A; MANTZOROS CS; HAMPTON TG; KATZ SE; TRAVERS KE; FLIER JS; MORGAN JP; DOUGLAS PS
      CARDIOVASCULAR PHENOTYPE OF TRANSGENIC MICE WITH REDUCED BROWN FAT

      Circulation
    80. VIDALPUIG A; SOLANES G; GRUJIC D; FLIER JS; LOWELL BB
      UCP3 - AN UNCOUPLING PROTEIN HOMOLOG EXPRESSED PREFERENTIALLY AND ABUNDANTLY IN SKELETAL-MUSCLE AND BROWN ADIPOSE-TISSUE

      Biochemical and biophysical research communications
    81. SPIEGELMAN BM; FLIER JS
      ADIPOGENESIS AND OBESITY - ROUNDING OUT THE BIG PICTURE

      Cell
    82. AHIMA RS; PRABAKARAN D; MANTZOROS C; QU DQ; LOWELL B; MARATOSFLIER E; FLIER JS
      ROLE OF LEPTIN IN THE NEUROENDOCRINE RESPONSE TO FASTING

      Nature
    83. LUDWIG DS; VIDALPUIG A; OBRIEN RM; PRINTZ RL; GRANNER DK; MOLLER DE; FLIER JS
      EXAMINATION OF THE PHOSPHOENOLPYRUVATE CARBOXYKINASE GENE PROMOTER INPATIENTS WITH NONINSULIN-DEPENDENT DIABETES-MELLITUS

      The Journal of clinical endocrinology and metabolism
    84. GABBAY RA; SUTHERLAND C; GNUDI L; KAHN BB; OBRIEN RM; GRANNER DK; FLIER JS
      INSULIN REGULATION OF PHOSPHOENOLPYRUVATE CARBOXYKINASE GENE-EXPRESSION DOES NOT REQUIRE ACTIVATION OF THE RAS MITOGEN-ACTIVATED PROTEIN-KINASE SIGNALING PATHWAY

      The Journal of biological chemistry
    85. HOUSEKNECHT KL; ZHU AX; GNUDI L; HAMANN A; ZIERATH JR; TOZZO E; FLIER JS; KAHN BB
      OVEREXPRESSION OF HA-RAS SELECTIVELY IN ADIPOSE-TISSUE OF TRANSGENIC MICE - EVIDENCE FOR ENHANCED SENSITIVITY TO INSULIN

      The Journal of biological chemistry
    86. ZHANG B; GRAZIANO MP; DOEBBER TW; LEIBOWITZ MD; WHITECARRINGTON S; SZALKOWSKI DM; HEY PJ; WU M; CULLINAN CA; BAILEY P; LOLLMANN B; FREDERICH R; FLIER JS; STRADER CD; SMITH RG
      DOWN-REGULATION OF THE EXPRESSION OF THE OBESE GENE BY AN ANTIDIABETIC THIAZOLIDINEDIONE IN ZUCKER DIABETIC FATTY RATS AND DB DB MICE/

      The Journal of biological chemistry
    87. MOLLER DE; CHANG PY; YASPELKIS BB; FLIER JS; WALLBERGHENRIKSSON H; IVY JL
      TRANSGENIC MICE WITH MUSCLE-SPECIFIC INSULIN-RESISTANCE DEVELOP INCREASED ADIPOSITY, IMPAIRED GLUCOSE-TOLERANCE, AND DYSLIPIDEMIA

      Endocrinology
    88. HAMANN A; FLIER JS; LOWELL BB
      DECREASED BROWN FAT MARKEDLY ENHANCES SUSCEPTIBILITY TO DIET-INDUCED OBESITY, DIABETES, AND HYPERLIPIDEMIA

      Endocrinology
    89. MANTZOROS CS; QU DQ; FREDERICH RC; SUSULIC VS; LOWELL BB; MARATOSFLIER E; FLIER JS
      ACTIVATION OF BETA(3) ADRENERGIC-RECEPTORS SUPPRESSES LEPTIN EXPRESSION AND MEDIATES A LEPTIN-INDEPENDENT INHIBITION OF FOOD-INTAKE IN MICE

      Diabetes
    90. MAFFEI M; STOFFEL M; BARONE M; MOON B; DAMMERMAN M; RAVUSSIN E; BOGARDUS C; LUDWIG DS; FLIER JS; TALLEY M; AUERBACH S; FRIEDMAN JM
      ABSENCE OF MUTATIONS IN THE HUMAN OB GENE IN OBESE-DIABETIC SUBJECTS

      Diabetes
    91. HOUSEKNECHT KL; MANTZOROS CS; KULIAWAT R; HADRO E; FLIER JS; KAHN BB
      EVIDENCE FOR LEPTIN BINDING TO PROTEINS IN SERUM OF RODENTS AND HUMANS - MODULATION WITH OBESITY

      Diabetes
    92. HOUSEKNECHT KL; FLIER SN; FREVERT EU; FREDERICH RC; FLIER JS; KAHN BB
      LEPTIN SECRETION CORRELATES WITH ADIPOCYTE SIZE IN GENETIC AND DIETARY OBESITY

      Diabetes
    93. FREDERICH RC; HAMANN A; ANDERSON S; LOLLMANN B; LOWELL BB; FLIER JS
      LEPTIN LEVELS REFLECT BODY LIPID-CONTENT IN MICE - EVIDENCE FOR DIET-INDUCED RESISTANCE TO LEPTIN ACTION

      Nature medicine
    94. MOSES AC; MORROW LA; OBRIEN M; MOLLER DE; FLIER JS
      INSULIN-LIKE GROWTH-FACTOR I(RHIGF-I) AS A THERAPEUTIC AGENT FOR HYPERINSULINEMIC INSULIN-RESISTANT DIABETES-MELLITUS

      Diabetes research and clinical practice
    95. FLIER JS
      THE ADIPOCYTE - STORAGE DEPOT OR NODE ON THE ENERGY INFORMATION SUPERHIGHWAY

      Cell
    96. FREDERICH RC; LOLLMANN B; HAMANN A; NAPOLITANOROSEN A; KAHN BB; LOWELL BB; FLIER JS
      EXPRESSION OF OB MESSENGER-RNA AND ITS ENCODED PROTEIN IN RODENTS - IMPACT OF NUTRITION AND OBESITY

      The Journal of clinical investigation
    97. LOWELL BB; FLIER JS
      THE POTENTIAL SIGNIFICANCE OF BETA(3) ADRENERGIC-RECEPTORS

      The Journal of clinical investigation
    98. SUSULIC VS; FREDERICH RC; LAWITTS J; TOZZO E; KAHN BB; HARPER ME; HIMMSHAGEN J; FLIER JS; LOWELL BB
      TARGETED DISRUPTION OF THE BETA(3)-ADRENERGIC RECEPTOR GENE

      The Journal of biological chemistry
    99. HAMANN A; BENECKE H; LEMARCHANDBRUSTEL Y; SUSULIC VS; LOWELL BB; FLIER JS
      CHARACTERIZATION OF INSULIN-RESISTANCE AND NIDDM IN TRANSGENIC MICE WITH REDUCED BROWN FAT

      Diabetes
    100. GNUDI L; ZHU AX; HAMANN A; HOUSEKNECHT KL; FLIER JS; KAHN BB
      OBESITY AND DIVERGENT EFFECTS ON INSULIN SIGNALING IN TRANSGENIC MICEEXPRESSING A DOMINANT-NEGATIVE MUTANT RAS

      Diabetes


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Documento generato il 25/10/20 alle ore 23:30:51