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1. Dietrich, CG; Ottenhoff, R; de Waart, DR; Elferink, RPJO
   Role of MRP2 and GSH in intrahepatic cycling of toxins
   TOXICOLOGY
   
   C.G. Dietrich et al., "Role of MRP2 and GSH in intrahepatic cycling of toxins", TOXICOLOGY, 167(1), 2001, pp. 73-81
2. Eppens, EF; van Mil, SWC; de Vree, JM; Mok, KS; Juijn, JA; Elferink, RPJO; Berger, R; Houwen, RHJ; Klomp, LWJ
   FIC1, the protein affected in two forms of hereditary cholestasis, is localized in the cholangiocyte and the canalicular membrane of the hepatocyte
   JOURNAL OF HEPATOLOGY
   
   E.F. Eppens et al., "FIC1, the protein affected in two forms of hereditary cholestasis, is localized in the cholangiocyte and the canalicular membrane of the hepatocyte", J HEPATOL, 35(4), 2001, pp. 436-443
3. Voshol, PJ; Koopen, NR; de Vree, JML; Havinga, R; Princen, HMG; Elferink, RPJO; Groen, AK; Kuipers, F
   Dietary cholesterol does not normalize low plasma cholesterol levels but induces hyperbilirubinemia and hypercholanemia in Mdr2 P-glycoprotein-deficient mice
   JOURNAL OF HEPATOLOGY
   
   P.J. Voshol et al., "Dietary cholesterol does not normalize low plasma cholesterol levels but induces hyperbilirubinemia and hypercholanemia in Mdr2 P-glycoprotein-deficient mice", J HEPATOL, 34(2), 2001, pp. 202-209
4. Dietrich, CG; de Waart, DR; Ottenhoff, R; Bootsma, AH; van Gennip, AH; Elferink, RPJO
   Mrp2-deficiency in the rat impairs biliary and intestinal excretion and influences metabolism and disposition of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
   CARCINOGENESIS
   
   C.G. Dietrich et al., "Mrp2-deficiency in the rat impairs biliary and intestinal excretion and influences metabolism and disposition of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)", CARCINOGENE, 22(5), 2001, pp. 805-811
5. Dietrich, CG; Ottenhoff, R; de Waart, DR; Elferink, RPJO
   Lack of UGT1 isoforms in Gunn rats changes metabolic ratio and facilitatesexcretion of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
   TOXICOLOGY AND APPLIED PHARMACOLOGY
   
   C.G. Dietrich et al., "Lack of UGT1 isoforms in Gunn rats changes metabolic ratio and facilitatesexcretion of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine", TOX APPL PH, 170(2), 2001, pp. 137-143
6. Dietrich, CG; De Waart, DR; Ottenhoff, R; Schoots, IG; Elferink, RPJO
   Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats
   MOLECULAR PHARMACOLOGY
   
   C.G. Dietrich et al., "Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats", MOLEC PHARM, 59(5), 2001, pp. 974-980
7. Jacquemin, E; de Vree, JML; Cresteil, D; Sokal, EM; Sturm, E; Dumont, M; Scheffer, GL; Paul, M; Burdelski, M; Bosma, PJ; Bernard, O; Hadchouel, M; Elferink, RPJO
   The wide spectrum of multidrug resistance 3 deficiency: From neonatal cholestasis to cirrhosis of adulthood
   GASTROENTEROLOGY
   
   E. Jacquemin et al., "The wide spectrum of multidrug resistance 3 deficiency: From neonatal cholestasis to cirrhosis of adulthood", GASTROENTY, 120(6), 2001, pp. 1448-1458
8. Elferink, RPJO; Groen, AK
   Mechanisms of biliary lipid secretion and their role in lipid homeostasis
   SEMINARS IN LIVER DISEASE
   
   R.P.J.O. Elferink e A.K. Groen, "Mechanisms of biliary lipid secretion and their role in lipid homeostasis", SEM LIV DIS, 20(3), 2000, pp. 293-305
9. De Vree, JML; Ottenhoff, R; Bosma, PJ; Smith, AJ; Aten, J; Elferink, RPJO
   Correction of liver disease by hepatocyte transplantation in a mouse modelof progressive familial intrahepatic cholestasis
   GASTROENTEROLOGY
   
   J.M.L. De Vree et al., "Correction of liver disease by hepatocyte transplantation in a mouse modelof progressive familial intrahepatic cholestasis", GASTROENTY, 119(6), 2000, pp. 1720-1730
10. Voshol, PJ; Minich, DM; Havinga, R; Elferink, RPJO; Verkade, HJJ; Groen, AK; Kuipers, F
    Postprandial chylomicron formation and fat absorption in multidrug resistance gene 2 P-glycoprotein-deficient mice
    GASTROENTEROLOGY
    
    P.J. Voshol et al., "Postprandial chylomicron formation and fat absorption in multidrug resistance gene 2 P-glycoprotein-deficient mice", GASTROENTY, 118(1), 2000, pp. 173-182
11. Scheffer, GL; Kool, M; Heijn, M; de Haas, M; Pijnenborg, ACLM; Wijnholds, J; van Helvoort, A; de Jong, MC; Hooijberg, JH; Mol, CAAM; van der Linden, M; de Vree, JML; van der Valk, P; Elferink, RPJO; Borst, P; Scheper, RJ
    Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies
    CANCER RESEARCH
    
    G.L. Scheffer et al., "Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies", CANCER RES, 60(18), 2000, pp. 5269-5277
12. Elferink, RPJO; Groen, AK
    The mechanism of biliary lipid secretion and its defects
    GASTROENTEROLOGY CLINICS OF NORTH AMERICA
    
    R.P.J.O. Elferink e A.K. Groen, "The mechanism of biliary lipid secretion and its defects", GASTRO CLIN, 28(1), 1999, pp. 59
13. Paulusma, CC; van Geer, MA; Evers, R; Heijn, M; Ottenhoff, R; Borst, P; Elferink, RPJO
    Canalicular multispecific organic onion transporter multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione
    BIOCHEMICAL JOURNAL
    
    C.C. Paulusma et al., "Canalicular multispecific organic onion transporter multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione", BIOCHEM J, 338, 1999, pp. 393-401
14. Smith, AJ; Elferink, RPJO
    Liver gene disruptions: winners by KO?
    JOURNAL OF HEPATOLOGY
    
    A.J. Smith e R.P.J.O. Elferink, "Liver gene disruptions: winners by KO?", J HEPATOL, 31(4), 1999, pp. 752-759
15. van Helvoort, A; de Brouwer, A; Ottenhoff, R; Brouwers, JFHM; Wijnholds, J; Beijnen, JH; Rijneveld, A; van der Poll, T; van der Valk, MA; Majoor, D; Voorhout, W; Wirtz, KWA; Elferink, RPJO; Borst, P
    Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    A. van Helvoort et al., "Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces", P NAS US, 96(20), 1999, pp. 11501-11506
16. Kool, M; van der Linden, M; de Haas, M; Scheffer, GL; de Vree, JML; Smith, AJ; Jansen, G; Peters, GJ; Ponne, N; Scheper, RJ; Elferink, RPJO; Baas, F; Borst, P
    MRP3, an organic anion transporter able to transport anti-cancer drugs
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    M. Kool et al., "MRP3, an organic anion transporter able to transport anti-cancer drugs", P NAS US, 96(12), 1999, pp. 6914-6919
17. Frijters, CMG; Tuijn, CJ; Ottenhoff, R; Zegers, BN; Groen, AK; Elferink, RPJO
    The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids
    JOURNAL OF LIPID RESEARCH
    
    C.M.G. Frijters et al., "The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids", J LIPID RES, 40(11), 1999, pp. 1950-1957
18. Bolder, U; Trang, NV; Hagey, LR; Schteingart, CD; Ton-Nu, HT; Cerre, C; Elferink, RPJO; Hofmann, AF
    Sulindac is excreted into bile by a canalicular bile salt pump and undergoes a cholehepatic circulation in rats
    GASTROENTEROLOGY
    
    U. Bolder et al., "Sulindac is excreted into bile by a canalicular bile salt pump and undergoes a cholehepatic circulation in rats", GASTROENTY, 117(4), 1999, pp. 962-971
19. de Vree, JML; Romijn, JA; Mok, KS; Mathus-Vliegen, LMH; Stoutenbeek, CP; Ostrow, JD; Tytgat, GNJ; Sauerwein, HP; Elferink, RPJO; Groen, AK
    Lack of enteral nutrition during critical illness is associated with profound decrements in biliary lipid concentrations
    AMERICAN JOURNAL OF CLINICAL NUTRITION
    
    J.M.L. de Vree et al., "Lack of enteral nutrition during critical illness is associated with profound decrements in biliary lipid concentrations", AM J CLIN N, 70(1), 1999, pp. 70-77
20. FRIJTERS CMG; TUIJN CJ; HOEK FJ; GROEN AK; ELFERINK RPJO; ZEGERS BN
    REVERSED-PHASE LIQUID-CHROMATOGRAPHIC METHOD FOR THE DETERMINATION OF7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL-LABELED LIPID ANALOGS
    Journal of chromatography B. Biomedical sciences and applications
    
    C.M.G. Frijters et al., "REVERSED-PHASE LIQUID-CHROMATOGRAPHIC METHOD FOR THE DETERMINATION OF7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL-LABELED LIPID ANALOGS", Journal of chromatography B. Biomedical sciences and applications, 710(1-2), 1998, pp. 9-16
21. SEITZ S; KRETZROMMEL A; ELFERINK RPJO; BOELSTERLI UA
    SELECTIVE PROTEIN ADDUCT FORMATION OF DICLOFENAC GLUCURONIDE IS CRITICALLY DEPENDENT ON THE RAT CANALICULAR CONJUGATE EXPORT PUMP (MRP2)
    Chemical research in toxicology
    
    S. Seitz et al., "SELECTIVE PROTEIN ADDUCT FORMATION OF DICLOFENAC GLUCURONIDE IS CRITICALLY DEPENDENT ON THE RAT CANALICULAR CONJUGATE EXPORT PUMP (MRP2)", Chemical research in toxicology, 11(5), 1998, pp. 513-519
22. DEVREE JML; OTTENHOFF R; SMITH AJ; ATEN J; GROEN AK; ELFERINK RPJO
    RAPID CORRECTION OF MDR2 DEFICIENCY BY TRANSPLANTATION OF MDR3 TRANSGENIC HEPATOCYTES
    Hepatology
    
    J.M.L. Devree et al., "RAPID CORRECTION OF MDR2 DEFICIENCY BY TRANSPLANTATION OF MDR3 TRANSGENIC HEPATOCYTES", Hepatology, 28(4), 1998, pp. 897-897
23. SMITH AJ; DEVREE JML; OTTENHOFF R; ELFERINK RPJO; SCHINKEL AH; BORST P
    HEPATOCYTE-SPECIFIC EXPRESSION OF THE HUMAN MDR3 P-GLYCOPROTEIN GENE RESTORES THE BILIARY PHOSPHATIDYLCHOLINE EXCRETION ABSENT IN MDR2 (- -) MICE/
    Hepatology
    
    A.J. Smith et al., "HEPATOCYTE-SPECIFIC EXPRESSION OF THE HUMAN MDR3 P-GLYCOPROTEIN GENE RESTORES THE BILIARY PHOSPHATIDYLCHOLINE EXCRETION ABSENT IN MDR2 (- -) MICE/", Hepatology, 28(2), 1998, pp. 530-536
24. ELFERINK RPJO; HENEGOUWEN GPV
    CRACKING THE GENETIC-CODE FOR BENIGN RECURRENT AND PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS
    Journal of hepatology
    
    R.P.J.O. Elferink e G.P.V. Henegouwen, "CRACKING THE GENETIC-CODE FOR BENIGN RECURRENT AND PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS", Journal of hepatology, 29(2), 1998, pp. 317-320
25. DEVREE JML; JACQUEMIN E; STURM E; CRESTEIL D; BOSMA PJ; ATEN J; DELEUZE JF; DESROCHERS M; BURDELSKI M; BERNARD O; ELFERINK RPJO; HADCHOUEL M
    MUTATIONS IN THE MDR3 GENE CAUSE PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS
    Proceedings of the National Academy of Sciences of the United Statesof America
    
    J.M.L. Devree et al., "MUTATIONS IN THE MDR3 GENE CAUSE PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS", Proceedings of the National Academy of Sciences of the United Statesof America, 95(1), 1998, pp. 282-287
26. ELFERINK RPJO; OTTENHOFF R; VANMARLE J; FRUJTERS CMG; SMITH AJ; GROEN AK
    CLASS-III P-GLYCOPROTEINS MEDIATE THE FORMATION OF LIPOPROTEIN-X IN THE MOUSE
    The Journal of clinical investigation
    
    R.P.J.O. Elferink et al., "CLASS-III P-GLYCOPROTEINS MEDIATE THE FORMATION OF LIPOPROTEIN-X IN THE MOUSE", The Journal of clinical investigation, 102(9), 1998, pp. 1749-1757
27. EVERS R; KOOL M; VANDEEMTER L; JANSSEN H; CALAFAT J; OOMEN LCJM; PAULUSMA CC; ELFERINK RPJO; BAAS F; SCHINKEL AH; BORSI P
    DRUG EXPORT ACTIVITY OF THE HUMAN CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER IN POLARIZED KIDNEY MDCK CELLS EXPRESSING CMOAT (MRP2) CDNA
    The Journal of clinical investigation
    
    R. Evers et al., "DRUG EXPORT ACTIVITY OF THE HUMAN CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER IN POLARIZED KIDNEY MDCK CELLS EXPRESSING CMOAT (MRP2) CDNA", The Journal of clinical investigation, 101(7), 1998, pp. 1310-1319
28. VOSHOL PJ; HAVINGA R; WOLTERS H; OTTENHOFF R; PRINCEN HMG; ELFERINK RPJO; GROEN AK; KUIPERS F
    REDUCED PLASMA-CHOLESTEROL AND INCREASED FECAL STEROL LOSS IN MULTIDRUG-RESISTANCE GENE-2 P-GLYCOPROTEIN-DEFICIENT MICE
    Gastroenterology
    
    P.J. Voshol et al., "REDUCED PLASMA-CHOLESTEROL AND INCREASED FECAL STEROL LOSS IN MULTIDRUG-RESISTANCE GENE-2 P-GLYCOPROTEIN-DEFICIENT MICE", Gastroenterology, 114(5), 1998, pp. 1024-1034
29. SEWNATH ME; LEVELS JHM; VANDEVENTER SJH; MAAS MAW; ELFERINK RPJO; ABRAHAMS PR; GOUMA DJ
    A SHIFT OF LIPOPROTEIN BOUND ENDOTOXIN IN BILE-DUCT LIGATED RATS
    Gastroenterology
    
    M.E. Sewnath et al., "A SHIFT OF LIPOPROTEIN BOUND ENDOTOXIN IN BILE-DUCT LIGATED RATS", Gastroenterology, 114(4), 1998, pp. 579-579
30. SEPPEN J; TADA K; OTTENHOFF R; SENGUPTA K; CHOWDHURY NR; CHOWDHURY JR; BOSMA PJ; ELFERINK RPJO
    TRANSPLANTATION OF GUNN-RATS WITH AUTOLOGOUS FIBROBLASTS EXPRESSING BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE - CORRECTION OF GENETIC DEFICIENCY AND TUMOR-FORMATION
    Human gene therapy
    
    J. Seppen et al., "TRANSPLANTATION OF GUNN-RATS WITH AUTOLOGOUS FIBROBLASTS EXPRESSING BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE - CORRECTION OF GENETIC DEFICIENCY AND TUMOR-FORMATION", Human gene therapy, 8(1), 1997, pp. 27-36
31. PAULUSMA CC; ELFERINK RPJO
    THE CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER AND CONJUGATED HYPERBILIRUBINEMIA IN RAT AND MAN
    Journal of molecular medicine
    
    C.C. Paulusma e R.P.J.O. Elferink, "THE CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER AND CONJUGATED HYPERBILIRUBINEMIA IN RAT AND MAN", Journal of molecular medicine, 75(6), 1997, pp. 420-428
32. ELFERINK RPJO; TYTGAT GNJ; GROEN AK
    THE ROLE OF MDR2 P-GLYCOPROTEIN IN HEPATOBILIARY LIPID TRANSPORT
    The FASEB journal
    
    R.P.J.O. Elferink et al., "THE ROLE OF MDR2 P-GLYCOPROTEIN IN HEPATOBILIARY LIPID TRANSPORT", The FASEB journal, 11(1), 1997, pp. 19-28
33. JACQUEMIN E; DEVREE JML; STURM E; CRESTEIL D; BOSMA PJ; ATEN J; DELEUZE JF; DESROCHERS M; BURDELSKI M; BERNARD O; HADCHOUEL M; ELFERINK RPJO
    MUTATIONS IN THE MDR3 GENE ARE RESPONSIBLE FOR A SUBTYPE OF PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS (PFIC)
    Hepatology
    
    E. Jacquemin et al., "MUTATIONS IN THE MDR3 GENE ARE RESPONSIBLE FOR A SUBTYPE OF PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS (PFIC)", Hepatology, 26(4), 1997, pp. 480-480
34. PAULUSMA CC; VANGEER M; HEIJN M; EVERS R; OTTENHOFF R; ELFERINK RPJO
    THE CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER MEDIATES TRANSPORT OF REDUCED GLUTATHIONE
    Hepatology
    
    C.C. Paulusma et al., "THE CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER MEDIATES TRANSPORT OF REDUCED GLUTATHIONE", Hepatology, 26(4), 1997, pp. 656-656
35. FRIJTERS CMG; ELFERINK RPJO; GROEN AK
    DBSP INDUCED UNCOUPLING OF BILIARY LIPID FROM BILE-SALT (BS) SECRETION IS DETERMINED EXCLUSIVELY BY BS CONCENTRATION
    Hepatology
    
    C.M.G. Frijters et al., "DBSP INDUCED UNCOUPLING OF BILIARY LIPID FROM BILE-SALT (BS) SECRETION IS DETERMINED EXCLUSIVELY BY BS CONCENTRATION", Hepatology, 26(4), 1997, pp. 662-662
36. VOSHOL PJ; KOOPEN NR; HAVINGA R; ELFERINK RPJO; GROEN AK; KUIPERS F
    HEPATOTOXIC ACTIONS OF DIETARY-CHOLESTEROL IN MDR2 P-GLYCOPROTEIN-DEFICIENT MICE
    Hepatology
    
    P.J. Voshol et al., "HEPATOTOXIC ACTIONS OF DIETARY-CHOLESTEROL IN MDR2 P-GLYCOPROTEIN-DEFICIENT MICE", Hepatology, 26(4), 1997, pp. 663-663
37. FRIJTERS CMG; OTTENHOFF R; VANWIJLAND MJA; VANNIEUWKERK CMJ; GROEN AK; ELFERINK RPJO
    REGULATION OF MDR2 P-GLYCOPROTEIN EXPRESSION BY BILE-SALTS
    Biochemical journal
    
    C.M.G. Frijters et al., "REGULATION OF MDR2 P-GLYCOPROTEIN EXPRESSION BY BILE-SALTS", Biochemical journal, 321, 1997, pp. 389-395
38. FRIJTERS CMG; GROEN AK; ELFERINK RPJO
    MDR2 P-GLYCOPROTEIN-MEDIATED LIPID SECRETION AND ITS RELEVANCE TO BILIARY DRUG TRANSPORT
    Advanced drug delivery reviews
    
    C.M.G. Frijters et al., "MDR2 P-GLYCOPROTEIN-MEDIATED LIPID SECRETION AND ITS RELEVANCE TO BILIARY DRUG TRANSPORT", Advanced drug delivery reviews, 25(2-3), 1997, pp. 201-215
39. VANNIEUWERK CMJ; GROEN AK; OTTENHOFF R; VANWIJLAND M; WEERMAN MAV; TYTGAT GNJ; OFFERHAUS JJA; ELFERINK RPJO
    THE ROLE OF BILE-SALT COMPOSITION IN LIVER PATHOLOGY OF MDR2 (- -) MICE - DIFFERENCES BETWEEN MALES AND FEMALES/
    Journal of hepatology
    
    C.M.J. Vannieuwerk et al., "THE ROLE OF BILE-SALT COMPOSITION IN LIVER PATHOLOGY OF MDR2 (- -) MICE - DIFFERENCES BETWEEN MALES AND FEMALES/", Journal of hepatology, 26(1), 1997, pp. 138-145
40. CRAWFORD AR; SMITH AJ; HATCH VC; ELFERINK RPJO; BORST P; CRAWFORD JM
    HEPATIC SECRETION OF PHOSPHOLIPID-VESICLES IN THE MOUSE CRITICALLY DEPENDS ON MDR2 OR MDR3 P-GLYCOPROTEIN EXPRESSION - VISUALIZATION BY ELECTRON-MICROSCOPY
    The Journal of clinical investigation
    
    A.R. Crawford et al., "HEPATIC SECRETION OF PHOSPHOLIPID-VESICLES IN THE MOUSE CRITICALLY DEPENDS ON MDR2 OR MDR3 P-GLYCOPROTEIN EXPRESSION - VISUALIZATION BY ELECTRON-MICROSCOPY", The Journal of clinical investigation, 100(10), 1997, pp. 2562-2567
41. DEVREE JML; ROMIJN JA; MATHUSVLIEGEN EMH; OSTROW JD; SAUERWEIN HP; STOUTENBEEK CP; TYTGAT GNJ; ELFERINK RPJO; GROEN AK
    IMPAIRED BILIARY LIPID SECRETION IN CRITICALLY-ILL PATIENTS
    Gastroenterology
    
    J.M.L. Devree et al., "IMPAIRED BILIARY LIPID SECRETION IN CRITICALLY-ILL PATIENTS", Gastroenterology, 112(4), 1997, pp. 1256-1256
42. PAULUSMA CC; BOSMA PJ; BAKKER CTM; SCHEFFER GL; SCHEPER RJ; ELFERINK RPJO
    DIFFERENTIAL LOCALIZATION OF 2 HOMOLOGOUS ATP-DEPENDENT ORGANIC ANIONTRANSPORTERS
    Molecular biology of the cell
    
    C.C. Paulusma et al., "DIFFERENTIAL LOCALIZATION OF 2 HOMOLOGOUS ATP-DEPENDENT ORGANIC ANIONTRANSPORTERS", Molecular biology of the cell, 7, 1996, pp. 1492-1492
43. ELFERINK RPJO
    TRANSPORT OF OPIOID-PEPTIDES BY MDR1 P-GLYCOPROTEIN
    Molecular biology of the cell
    
    R.P.J.O. Elferink, "TRANSPORT OF OPIOID-PEPTIDES BY MDR1 P-GLYCOPROTEIN", Molecular biology of the cell, 7, 1996, pp. 2520-2520
44. DEVREE JML; SMITH A; OTTENHOFF R; SCHINKEL AH; BORST P; GROEN AK; OFFERHAUS GJA; ELFERINK RPJO
    BORDERLINE PATHOLOGY IN MDR2 (- -) RESCUE IN MICE - A NEW MODEL TO STUDY NONSUPPURATIVE CHOLANGITIS/
    Hepatology
    
    J.M.L. Devree et al., "BORDERLINE PATHOLOGY IN MDR2 (- -) RESCUE IN MICE - A NEW MODEL TO STUDY NONSUPPURATIVE CHOLANGITIS/", Hepatology, 24(4), 1996, pp. 786-786
45. VANDERVERRE CN; SCHOEMAKER B; BAKKER C; VANDERMEER R; JANSEN PLM; ELFERINK RPJO
    INFLUENCE OF DIETARY CALCIUM-PHOSPHATE ON THE DISPOSITION OF BILIRUBIN IN RATS WITH UNCONJUGATED HYPERBILIRUBINEMIA
    Hepatology
    
    C.N. Vanderverre et al., "INFLUENCE OF DIETARY CALCIUM-PHOSPHATE ON THE DISPOSITION OF BILIRUBIN IN RATS WITH UNCONJUGATED HYPERBILIRUBINEMIA", Hepatology, 24(3), 1996, pp. 620-626
46. SEPPEN J; TADA K; HELLWIG S; BAKKER CTM; PRASAD VR; CHOWDHURY NR; CHOWDHURY JR; BOSMA PJ; ELFERINK RPJO
    BILIRUBIN GLUCURONIDATION BY INTACT GUNN RAT FIBROBLASTS EXPRESSING BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE
    Biochemical journal
    
    J. Seppen et al., "BILIRUBIN GLUCURONIDATION BY INTACT GUNN RAT FIBROBLASTS EXPRESSING BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE", Biochemical journal, 314, 1996, pp. 477-483
47. ELFERINK RPJO; FRIJTERS CMG; PAULUSMA C; GROEN AK
    REGULATION OF CANALICULAR TRANSPORT ACTIVITIES
    Journal of hepatology
    
    R.P.J.O. Elferink et al., "REGULATION OF CANALICULAR TRANSPORT ACTIVITIES", Journal of hepatology, 24, 1996, pp. 94-99
48. PAULUSMA CC; BOSMA PJ; ZAMAN GJR; BAKKER CTM; OTTER M; SCHEFFER GL; SCHEPER RJ; BORST P; ELFERINK RPJO
    CONGENITAL JAUNDICE IN RATS WITH A MUTATION IN A MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN GENE
    Science
    
    C.C. Paulusma et al., "CONGENITAL JAUNDICE IN RATS WITH A MUTATION IN A MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN GENE", Science, 271(5252), 1996, pp. 1126-1128
49. GROEN AK; ELFERINK RPJO; TAGER JM
    CONTROL ANALYSIS OF BILIARY LIPID SECRETION
    Journal of theoretical biology
    
    A.K. Groen et al., "CONTROL ANALYSIS OF BILIARY LIPID SECRETION", Journal of theoretical biology, 182(3), 1996, pp. 427-436
50. ELFERINK RPJO; OTTENHOFF R; VANWIJLAND M; FRIJTERS CMG; VANNIEUWKERK C; GROEN AK
    UNCOUPLING OF BILIARY PHOSPHOLIPID AND CHOLESTEROL SECRETION IN MICE WITH REDUCED EXPRESSION OF MDR2 P-GLYCOPROTEIN
    Journal of lipid research
    
    R.P.J.O. Elferink et al., "UNCOUPLING OF BILIARY PHOSPHOLIPID AND CHOLESTEROL SECRETION IN MICE WITH REDUCED EXPRESSION OF MDR2 P-GLYCOPROTEIN", Journal of lipid research, 37(5), 1996, pp. 1065-1075
51. EVERS R; ZAMAN GJR; VANDEEMTER L; JANSEN H; CALAFAT J; OOMEN LCJM; ELFERINK RPJO; BORST P; SCHINKEL AH
    BASOLATERAL LOCALIZATION AND EXPORT ACTIVITY OF THE HUMAN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN IN POLARIZED PIG-KIDNEY CELLS
    The Journal of clinical investigation
    
    R. Evers et al., "BASOLATERAL LOCALIZATION AND EXPORT ACTIVITY OF THE HUMAN MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN IN POLARIZED PIG-KIDNEY CELLS", The Journal of clinical investigation, 97(5), 1996, pp. 1211-1218
52. VANNIEUWKERK CMJ; ELFERINK RPJO; GROEN AK; OTTENHOFF R; TYTGAT GNJ; DINGEMANS KP; WEERMAN MAVB; OFFERHAUS GJA
    EFFECTS OF URSODEOXYCHOLATE AND CHOLATE FEEDING ON LIVER-DISEASE IN FVB MICE WITH A DISRUPTED MDR2 P-GLYCOPROTEIN GENE
    Gastroenterology
    
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53. GROEN AK; TYTGAT GNJ; ELFERINK RPJO
    CONTROL ANALYSIS OF BILIARY LIPID SECRETION
    Gastroenterology
    
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54. SEPPEN J; STEENKEN E; LINDHOUT D; BOSMA PJ; ELFERINK RPJO
    A MUTATION WHICH DISRUPTS THE HYDROPHOBIC CORE OF THE SIGNAL PEPTIDE OF BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE, AN ENDOPLASMIC-RETICULUM MEMBRANE-PROTEIN, CAUSES CRIGLER-NAJJAR TYPE-II
    FEBS letters
    
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55. STOUTHARD JML; ELFERINK RPJO; SAUERWEIN HP
    INTERLEUKIN-6 ENHANCES GLUCOSE-TRANSPORT IN 3T3-L1 ADIPOCYTES
    Biochemical and biophysical research communications
    
    J.M.L. Stouthard et al., "INTERLEUKIN-6 ENHANCES GLUCOSE-TRANSPORT IN 3T3-L1 ADIPOCYTES", Biochemical and biophysical research communications, 220(2), 1996, pp. 241-245
56. SEPPEN J; JANSEN PLM; ELFERINK RPJO
    IMMUNOAFFINITY PURIFICATION AND RECONSTITUTION OF THE HUMAN BILIRUBINPHENOL UDP-GLUCURONOSYLTRANSFERASE FAMILY
    Protein expression and purification
    
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57. ELFERINK RPJO; MEIJER DKF; KUIPERS F; JANSEN PLM; GROEN AK; GROOTHUIS GMM
    HEPATOBILIARY SECRETION OF ORGANIC-COMPOUNDS - MOLECULAR MECHANISMS OF MEMBRANE-TRANSPORT
    Biochimica et biophysica acta, MR. Reviews on biomembranes
    
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58. PAULUSMA CC; BOSMA PJ; BAKKER CTM; OTTER M; ZAMAN GJR; ELFERINK RPJO
    CLONING OF A LIVER-SPECIFIC MRP-HOMOLOG WHICH IS DEFICIENT IN THE TR RAT
    Hepatology
    
    C.C. Paulusma et al., "CLONING OF A LIVER-SPECIFIC MRP-HOMOLOG WHICH IS DEFICIENT IN THE TR RAT", Hepatology, 22(4), 1995, pp. 753-753
59. CRAWFORD JM; HATCH VC; GROEN AK; ELFERINK RPJO
    BILE CANALICULAR VESICLES ARE MARKEDLY DECREASED IN MDR2 KNOCKOUT MICE - ELECTRON-MICROSCOPY OF CRYOFIXED LIVER
    Hepatology
    
    J.M. Crawford et al., "BILE CANALICULAR VESICLES ARE MARKEDLY DECREASED IN MDR2 KNOCKOUT MICE - ELECTRON-MICROSCOPY OF CRYOFIXED LIVER", Hepatology, 22(4), 1995, pp. 840-840
60. FRIJTERS CMG; OTTENHOFF R; VANWIJLAND MJA; VANNIEUWKERK C; GROEN AK; ELFERINK RPJO
    REGULATION OF MDR2 P-GLYCOPROTEIN EXPRESSION BY BILE-SALTS
    Hepatology
    
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61. SEPPEN J; TADA K; HELLWIG S; CHOWDHURY JR; CHOWDHURY NR; BOSMA PJ; ELFERINK RPJO
    CORRECTION OF BILIRUBIN GLUCURONIDATION DEFICIENCY IN GUNN-RATS BY TRANSPLANTATION OF GUNN RAT FIBROBLASTS EXPRESSING BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE
    Hepatology
    
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62. ROELOFSEN H; BAKKER CTM; SCHOEMAKER B; HEIJN M; JANSEN PLM; ELFERINK RPJO
    REDISTRIBUTION OF CANALICULAR ORGANIC ANION TRANSPORT ACTIVITY IN ISOLATED AND CULTURED RAT HEPATOCYTES
    Hepatology
    
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63. ROELOFSEN H; SCHOEMAKER B; BAKKER C; OTTENHOFF R; JANSEN PLM; ELFERINK RPJO
    IMPAIRED HEPATOCANALICULAR ORGANIC ANION TRANSPORT IN ENDOTOXEMIC RATS
    American journal of physiology: Gastrointestinal and liver physiology
    
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64. ELFERINK RPJO; GROEN AK
    THE ROLE OF MDR2 P-GLYCOPROTEIN IN BILIARY LIPID SECRETION - CROSS-TALK BETWEEN CANCER-RESEARCH AND BILIARY PHYSIOLOGY
    Journal of hepatology
    
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65. BOSMA PJ; CHOWDHURY JR; BAKKER C; GANTLA S; DEBOER A; OOSTRA BA; LINDHOUT D; TYTGAT GNJ; JANSEN PLM; ELFERINK RPJO; CHOWDHURY NR
    THE GENETIC-BASIS OF THE REDUCED EXPRESSION OF BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE-1 IN GILBERTS-SYNDROME
    The New England journal of medicine
    
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66. VANDERVEERE CN; SHOEMAKER B; VANDERMEER R; GROEN AK; JANSEN PLM; ELFERINK RPJO
    RAPID ASSOCIATION OF UNCONJUGATED BILIRUBIN WITH AMORPHOUS CALCIUM-PHOSPHATE
    Journal of lipid research
    
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67. ELFERINK RPJO; OTTENHOFF R; VANWIJLAND M; SMIT JJM; SCHINKEL AH; GROEN AK
    REGULATION OF BILIARY LIPID SECRETION BY MDR2 P-GLYCOPROTEIN IN THE MOUSE
    The Journal of clinical investigation
    
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68. GROEN AK; VANWIJLAND MJA; FREDERIKS WM; SMIT JJM; SCHINKEL AH; ELFERINK RPJO
    REGULATION OF PROTEIN SECRETION INTO BILE - STUDIES IN MICE WITH A DISRUPTED MDR2 P-GLYCOPROTEIN GENE
    Gastroenterology
    
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69. VANNIEUWKERK CMJ; OTTENHOFF R; VONWIILAND M; DINGEMANS KP; WEERMAN MAV; TYTGAT GNJ; OFFERHAUS GJA; GROEN AK; ELFERINK RPJO
    INFLUENCE OF DIETARY CHOLATE AND URSODEOXYCHOLATE ON LIVER PATHOLOGY IN MDR2 KNOCKOUT MICE
    Gastroenterology
    
    C.M.J. Vannieuwkerk et al., "INFLUENCE OF DIETARY CHOLATE AND URSODEOXYCHOLATE ON LIVER PATHOLOGY IN MDR2 KNOCKOUT MICE", Gastroenterology, 108(4), 1995, pp. 1192-1192
70. KUIPERS F; WOLTERS H; HAVINGA R; VONK RJ; PRINCEN HMG; ELFERINK RPJO; GROEN AK
    INCREASED HEPATIC CHOLESTEROL-SYNTHESIS IN MDR2 P-GLYCOPROTEIN DEFICIENT MICE WITH IMPAIRED BILIARY CHOLESTEROL AND PHOSPHOLIPID SECRETION
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71. ELFERINK RPJO; OTTENHOFF R; VANWIJLAND M; FRIJTERS C; GROEN AK
    RESISTANCE OF THE CANALICULAR MEMBRANE AGAINST BILE-SALTS
    Hepatology
    
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72. ELFERINK RPJO; JANSEN PLM
    THE ROLE OF THE CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER IN THE DISPOSAL OF ENDOBIOTICS AND XENOBIOTICS
    Pharmacology & therapeutics
    
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73. ELFERINK RPJO; JANSEN PLM
    THE ROLE OF THE CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER IN THE DISPOSAL OF ENDOBIOTICS AND XENOBIOTICS
    Pharmacology & therapeutics
    
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74. VANWIJLAND MJA; KLINKSPOOR JH; DEWIT LT; ELFERINK RPJO; TYTGAT GNJ; GROEN AK
    HETEROGENEITY OF HUMAN GALLBLADDER MUCIN IN BILE
    Clinical science
    
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75. SEPPEN J; BOSMA PJ; GOLDHOORN BG; BAKKER CTM; CHOWDHURY JR; CHOWDHURY NR; JANSEN PLM; ELFERINK RPJO
    DISCRIMINATION BETWEEN CRIGLER-NAJJAR TYPE-I AND TYPE-II BY EXPRESSION OF MUTANT BILIRUBIN URIDINE DIPHOSPHATE-GLUCURONOSYLTRANSFERASE
    The Journal of clinical investigation
    
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76. BOSMA PJ; SEPPEN J; GOLDHOORN B; BAKKER C; ELFERINK RPJO; CHOWDHURY JR; CHOWDHURY NR; JANSEN PLM
    BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE-1 IS THE ONLY RELEVANT BILIRUBIN GLUCURONIDATING ISOFORM IN MAN (VOL 269, PG 17960, 1994)
    The Journal of biological chemistry
    
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77. BOSMA PJ; SEPPEN J; GOLDHOORN B; BAKKER C; ELFERINK RPJO; CHOWDHURY JR; CHOWDHURY NR; JANSEN PLM
    BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE-1 IS THE ONLY RELEVANT BILIRUBIN GLUCURONIDATING ISOFORM IN MAN
    The Journal of biological chemistry
    
    P.J. Bosma et al., "BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE-1 IS THE ONLY RELEVANT BILIRUBIN GLUCURONIDATING ISOFORM IN MAN", The Journal of biological chemistry, 269(27), 1994, pp. 17960-17964
78. ROELOFSEN H; VANDERVEERE CN; OTTENHOFF R; SCHOEMAKER B; JANSEN PLM; ELFERINK RPJO
    DECREASED BILIRUBIN TRANSPORT IN THE PERFUSED LIVER OF ENDOTOXEMIC RATS
    Gastroenterology
    
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79. KUIPERS F; SMIT JJM; ELFERINK RPJO; OTTENHOF R; SCHINKEL AH; VERKADE HJ; VONK RJ; BORST P; GROEN AK
    THE ROLE OF BILIARY CHOLESTEROL AND PHOSPHOLIPIDS IN THE REGULATION OF PLASMA-LIPID LEVELS - STUDIES IN MDR2 TRANSGENIC MICE
    Circulation
    
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80. KUIPERS F; SMIT JJM; ELFERINK RPJO; OTTENHOF R; SCHINKEL AH; VERKADE HJ; VONK RJ; BORST P; GROEN AK
    THE ROLE OF BILIARY CHOLESTEROL AND PHOSPHOLIPIDS IN THE REGULATION OF PLASMA-LIPID LEVELS - STUDIES IN MDR2 TRANSGENIC MICE
    Circulation
    
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81. MAUAD TH; VANNIEUWKERK CMJ; DINGEMANS KP; SMIT JJM; SCHINKEL AH; NOTENBOOM RGE; WEERMAN MAV; VERKRUISEN RP; GROEN AK; ELFERINK RPJO; VANDERVALK MA; BORST P; OFFERHAUS GJA
    MICE WITH HOMOZYGOUS DISRUPTION OF THE MDR2 P-GLYCOPROTEIN GENE - A NOVEL ANIMAL-MODEL FOR STUDIES OF NONSUPPURATIVE INFLAMMATORY CHOLANGITIS AND HEPATOCARCINOGENESIS
    The American journal of pathology
    
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82. VANDERVEERE CN; SCHOEMAKER B; VANDERMEER R; GROEN AK; JANSEN PLM; ELFERINK RPJO
    DIETARY CALCIUMPHOSPHATE LOWERS SERUM BILIRUBIN LEVELS IN GUNN-RATS
    Hepatology
    
    C.N. Vanderveere et al., "DIETARY CALCIUMPHOSPHATE LOWERS SERUM BILIRUBIN LEVELS IN GUNN-RATS", Hepatology, 18(4), 1993, pp. 10000127-10000127
83. BOSMA PJ; CHOWDHURY NR; GOLDHOORN B; SEPPEN J; ELFERINK RPJO; CHOWDHURY JR; JANSEN PLM
    BILIRUBIN-UDP-GLUCURONOSYLTRANSFERASE-1 IS THE PHYSIOLOGICALLY IMPORTANT BILIRUBIN GLUCURONIDATING ISOFORM IN HUMAN LIVER
    Hepatology
    
    P.J. Bosma et al., "BILIRUBIN-UDP-GLUCURONOSYLTRANSFERASE-1 IS THE PHYSIOLOGICALLY IMPORTANT BILIRUBIN GLUCURONIDATING ISOFORM IN HUMAN LIVER", Hepatology, 18(4), 1993, pp. 10000127-10000127
84. KOTHE MJC; BAKKER CTM; DEHAAN J; MAAS A; JANSEN PLM; ELFERINK RPJO
    CANALICULAR ORGANIC ANION TRANSPORT AFTER BILE-DUCT LIGATION AND RECONSTRUCTION IN THE RAT
    Hepatology
    
    M.J.C. Kothe et al., "CANALICULAR ORGANIC ANION TRANSPORT AFTER BILE-DUCT LIGATION AND RECONSTRUCTION IN THE RAT", Hepatology, 18(4), 1993, pp. 10000138-10000138
85. SMIT JJM; SCHINKEL AH; ELFERINK RPJO; GROEN AK; WAGENAAR E; VANDEEMTER L; MOL CAAM; OTTENHOFF R; VANDERLUGT NMT; VANROON M; VANDERVALK MA; OFFERHAUS GJA; BERNS AJM; BORST P
    HOMOZYGOUS DISRUPTION OF THE MURINE MDR2 P-GLYCOPROTEIN GENE LEADS TOLIVER-DISEASE
    Hepatology
    
    J.J.M. Smit et al., "HOMOZYGOUS DISRUPTION OF THE MURINE MDR2 P-GLYCOPROTEIN GENE LEADS TOLIVER-DISEASE", Hepatology, 18(4), 1993, pp. 10000142-10000142
86. GROEN AK; VANWIJLAND MJA; SMIT JJ; SCHINKEL AH; BORST P; ELFERINK RPJO
    BILIARY PROTEIN SECRETION IN THE MDR2 KNOCK-OUT MOUSE
    Hepatology
    
    A.K. Groen et al., "BILIARY PROTEIN SECRETION IN THE MDR2 KNOCK-OUT MOUSE", Hepatology, 18(4), 1993, pp. 10000180-10000180
87. ELFERINK RPJO; GROEN AK; OTTENHOFF R; SMIT JJM; SCHINKEL AH; BORST P
    MICE WITH A DISRUPTED MDR2 GENE DO NOT EXCRETE PHOSPHOLIPID INTO BILE
    Hepatology
    
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88. SMIT JJM; SCHINKEL AH; ELFERINK RPJO; GROEN AK; WAGENAAR E; VANDEEMTER L; MOL CAAM; OTTENHOFF R; VANDERLUGT NMT; VANROON MA; VANDERVALK MA; OFFERHAUS GJA; BERNS AJM; BORST P
    HOMOZYGOUS DISRUPTION OF THE MURINE MDR2 P-GLYCOPROTEIN GENE LEADS TOA COMPLETE ABSENCE OF PHOSPHOLIPID FROM BILE AND TO LIVER-DISEASE
    Cell
    
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89. BOSMA PJ; GOLDHOORN B; ELFERINK RPJO; SINAASAPPEL M; OOSTRA BA; JANSEN PLM
    A MUTATION IN BILIRUBIN URIDINE 5'-DIPHOSPHATE-GLUCURONOSYLTRANSFERASE ISOFORM-1 CAUSING CRIGLER-NAJJAR SYNDROME TYPE-II
    Gastroenterology
    
    P.J. Bosma et al., "A MUTATION IN BILIRUBIN URIDINE 5'-DIPHOSPHATE-GLUCURONOSYLTRANSFERASE ISOFORM-1 CAUSING CRIGLER-NAJJAR SYNDROME TYPE-II", Gastroenterology, 105(1), 1993, pp. 216-220
90. JANSEN PLM; VANKLINKEN JW; VANGELDER M; OTTENHOFF R; ELFERINK RPJO
    PRESERVED ORGANIC ANION TRANSPORT IN MUTANT TR- RATS WITH A HEPATOBILIARY SECRETION DEFECT
    The American journal of physiology
    
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