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1. Bolon, B; Carter, C; Daris, M; Morony, S; Capparelli, C; Hsieh, A; Mao, MF; Kostenuik, P; Dunstan, CR; Lacey, DL; Sheng, JZ
   Adenoviral delivery of osteoprotegerin ameliorates bone resorption in a mouse ovariectomy model of osteoporosis
   MOLECULAR THERAPY
   
   B. Bolon et al., "Adenoviral delivery of osteoprotegerin ameliorates bone resorption in a mouse ovariectomy model of osteoporosis", MOL THER, 3(2), 2001, pp. 197-205
2. Brown, JM; Vessella, RL; Kostenuik, PJ; Dunstan, CR; Lange, PH; Corey, E
   Serum osteoprotegerin levels are increased in patients with advanced prostate cancer
   CLINICAL CANCER RESEARCH
   
   J.M. Brown et al., "Serum osteoprotegerin levels are increased in patients with advanced prostate cancer", CLIN CANC R, 7(10), 2001, pp. 2977-2983
3. Ross, AB; Bateman, TA; Kostenuik, PJ; Ferguson, VL; Lacey, DL; Dunstan, CR; Simske, SJ
   The effects of osteoprotegerin on the mechanical properties of rat bone
   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
   
   A.B. Ross et al., "The effects of osteoprotegerin on the mechanical properties of rat bone", J MAT S-M M, 12(7), 2001, pp. 583-588
4. Bekker, PJ; Holloway, D; Nakanishi, A; Arrighi, M; Leese, PT; Dunstan, CR
   The effect of a single dose of osteoprotegerin in postmenopausal women
   JOURNAL OF BONE AND MINERAL RESEARCH
   
   P.J. Bekker et al., "The effect of a single dose of osteoprotegerin in postmenopausal women", J BONE MIN, 16(2), 2001, pp. 348-360
5. Bateman, TA; Dunstan, CR; Lacey, DL; Ferguson, VL; Ayers, RA; Simske, SJ
   Osteoprotegerin ameliorates sciatic nerve crush induced bone loss
   JOURNAL OF ORTHOPAEDIC RESEARCH
   
   T.A. Bateman et al., "Osteoprotegerin ameliorates sciatic nerve crush induced bone loss", J ORTHOP R, 19(4), 2001, pp. 518-523
6. Kostenuik, PJ; Capparelli, C; Morony, S; Adamu, S; Shimamoto, G; Shen, V; Lacey, DL; Dunstan, CR
   OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized rats
   ENDOCRINOLOGY
   
   P.J. Kostenuik et al., "OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized rats", ENDOCRINOL, 142(10), 2001, pp. 4295-4304
7. Morony, S; Capparelli, C; Sarosi, I; Lacey, DL; Dunstan, CR; Kostenuik, PJ
   Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden insyngeneic and nude mouse models of experimental bone metastasis
   CANCER RESEARCH
   
   S. Morony et al., "Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden insyngeneic and nude mouse models of experimental bone metastasis", CANCER RES, 61(11), 2001, pp. 4432-4436
8. Croucher, PI; Shipman, CM; Lippitt, J; Perry, M; Asosingh, K; Hijzen, A; Brabbs, AC; van Beek, EJR; Holen, I; Skerry, TM; Dunstan, CR; Russell, GR; Van Camp, B; Vanderkerken, K
   Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma
   BLOOD
   
   P.I. Croucher et al., "Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma", BLOOD, 98(13), 2001, pp. 3534-3540
9. Hofbauer, LC; Shui, CX; Riggs, BL; Dunstan, CR; Spelsberg, TC; O'Brien, T; Khosla, S
   Effects of immunosuppressants on receptor activator of NF-kappa B ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells
   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
   
   L.C. Hofbauer et al., "Effects of immunosuppressants on receptor activator of NF-kappa B ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells", BIOC BIOP R, 280(1), 2001, pp. 334-339
10. Bateman, TA; Dunstan, CR; Ferguson, VL; Lacey, DL; Ayers, RA; Simske, SJ
    Osteoprotegerin mitigates tail suspension-induced osteopenia
    BONE
    
    T.A. Bateman et al., "Osteoprotegerin mitigates tail suspension-induced osteopenia", BONE, 26(5), 2000, pp. 443-449
11. Dunstan, CR
    Osteoprotegerin and osteoprotegerin ligand mediate the local regulation ofbone resorption
    ENDOCRINOLOGIST
    
    C.R. Dunstan, "Osteoprotegerin and osteoprotegerin ligand mediate the local regulation ofbone resorption", ENDOCRINOLO, 10(1), 2000, pp. 18-26
12. Hofbauer, LC; Khosla, S; Dunstan, CR; Lacey, DL; Boyle, WJ; Riggs, BL
    The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption
    JOURNAL OF BONE AND MINERAL RESEARCH
    
    L.C. Hofbauer et al., "The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption", J BONE MIN, 15(1), 2000, pp. 2-12
13. Li, J; Sarosi, I; Yan, XQ; Morony, S; Capparelli, C; Tan, HL; McCabe, S; Elliott, R; Scully, S; Van, G; Kaufman, S; Juan, SC; Sun, Y; Tarpley, J; Martin, L; Christensen, K; McCabe, J; Kostenuik, P; Hsu, H; Fletcher, F; Dunstan, CR; Lacey, DL; Boyle, WJ
    RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    J. Li et al., "RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism", P NAS US, 97(4), 2000, pp. 1566-1571
14. Min, H; Morony, S; Sarosi, I; Dunstan, CR; Capparelli, C; Scully, S; Van, G; Kaufman, S; Kostenuik, PJ; Lacey, DL; Boyle, TJ; Simonet, WS
    Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis
    JOURNAL OF EXPERIMENTAL MEDICINE
    
    H. Min et al., "Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis", J EXP MED, 192(4), 2000, pp. 463-474
15. Gori, F; Hofbauer, LC; Dunstan, CR; Spelsberg, TC; Khosla, S; Riggs, BL
    The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated
    ENDOCRINOLOGY
    
    F. Gori et al., "The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated", ENDOCRINOL, 141(12), 2000, pp. 4768-4776
16. Capparelli, C; Kostenuik, PJ; Morony, S; Starnes, C; Weimann, B; Van, G; Scully, S; Qi, MY; Lacey, DL; Dunstan, CR
    Osteoprotegerin prevents and reverses hypercalcemia in a murine model of humoral hypercalcemia of malignancy
    CANCER RESEARCH
    
    C. Capparelli et al., "Osteoprotegerin prevents and reverses hypercalcemia in a murine model of humoral hypercalcemia of malignancy", CANCER RES, 60(4), 2000, pp. 783-787
17. Hofbauer, LC; Lacey, DL; Dunstan, CR; Spelsberg, TC; Riggs, BL; Khosla, S
    Interleukin-1 beta and tumor necrosis factor-alpha, but not interleukin-6,stimulate osteoprotegerin ligand gene expression in human osteoblastic cells
    BONE
    
    L.C. Hofbauer et al., "Interleukin-1 beta and tumor necrosis factor-alpha, but not interleukin-6,stimulate osteoprotegerin ligand gene expression in human osteoblastic cells", BONE, 25(3), 1999, pp. 255-259
18. Lomaga, MA; Yeh, WC; Sarosi, I; Duncan, GS; Furlonger, C; Ho, A; Morony, S; Capparelli, C; Van, G; Kaufman, S; van der Heiden, A; Itie, A; Wakeham, A; Khoo, W; Sasaki, T; Cao, ZD; Penninger, JM; Paige, CJ; Lacey, DL; Dunstan, CR; Boyle, WJ; Goeddel, DV; Mak, TW
    TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
    GENES & DEVELOPMENT
    
    M.A. Lomaga et al., "TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling", GENE DEV, 13(8), 1999, pp. 1015-1024
19. Morony, S; Capparelli, C; Lee, R; Shimamoto, G; Boone, T; Lacey, DL; Dunstan, CR
    A chimeric form of osteoprotegerin inhibits hypercalcemia and bone resorption induced by IL-1 beta, TNF-alpha, PTH, PTHrP, and 1,25(OH)(2)D-3
    JOURNAL OF BONE AND MINERAL RESEARCH
    
    S. Morony et al., "A chimeric form of osteoprotegerin inhibits hypercalcemia and bone resorption induced by IL-1 beta, TNF-alpha, PTH, PTHrP, and 1,25(OH)(2)D-3", J BONE MIN, 14(9), 1999, pp. 1478-1485
20. Dunstan, CR; Boyce, R; Boyce, BF; Garrett, IR; Izbicka, E; Burgess, WH; Mundy, GR
    Systemic administration of acidic fibroblast growth factor (FGF-1) prevents bone loss and increases new bone formation in ovariectomized rats
    JOURNAL OF BONE AND MINERAL RESEARCH
    
    C.R. Dunstan et al., "Systemic administration of acidic fibroblast growth factor (FGF-1) prevents bone loss and increases new bone formation in ovariectomized rats", J BONE MIN, 14(6), 1999, pp. 953-959
21. Shalhoub, V; Faust, J; Boyle, WJ; Dunstan, CR; Kelley, M; Kaufman, S; Scully, S; Van, G; Lacey, DL
    Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formationfrom human peripheral blood mononuclear cell precursors
    JOURNAL OF CELLULAR BIOCHEMISTRY
    
    V. Shalhoub et al., "Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formationfrom human peripheral blood mononuclear cell precursors", J CELL BIOC, 72(2), 1999, pp. 251-261
22. Kong, YY; Yoshida, H; Sarosi, I; Tan, HL; Timms, E; Capparelli, C; Morony, S; Oliveira-dos-Santos, AJ; Van, G; Itie, A; Khoo, W; Wakeham, A; Dunstan, CR; Lacey, DL; Mak, TW; Boyle, WJ; Penninger, JM
    OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    NATURE
    
    Y.Y. Kong et al., "OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis", NATURE, 397(6717), 1999, pp. 315-323
23. Hsu, HL; Lacey, DL; Dunstan, CR; Solovyev, I; Colombero, A; Timms, E; Tan, HL; Elliott, G; Kelley, MJ; Sarosi, I; Wang, L; Xia, XZ; Elliott, R; Chiu, L; Black, T; Scully, S; Capparelli, C; Morony, S; Shimamoto, G; Bass, MB; Boyle, WJ
    Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    H.L. Hsu et al., "Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand", P NAS US, 96(7), 1999, pp. 3540-3545
24. Burgess, TL; Qian, YX; Kaufman, S; Ring, BD; Van, G; Capparelli, C; Kelley, M; Hsu, HL; Boyle, WJ; Dunstan, CR; Hu, S; Lacey, DL
    The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts
    JOURNAL OF CELL BIOLOGY
    
    T.L. Burgess et al., "The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts", J CELL BIOL, 145(3), 1999, pp. 527-538
25. Hofbauer, LC; Khosla, S; Dunstan, CR; Lacey, DL; Spelsberg, TC; Riggs, BL
    Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells
    ENDOCRINOLOGY
    
    L.C. Hofbauer et al., "Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells", ENDOCRINOL, 140(9), 1999, pp. 4367-4370
26. Hofbauer, LC; Gori, F; Riggs, BL; Lacey, DL; Dunstan, CR; Spelsberg, TC; Khosla, S
    Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential paracrine mechanisms of glucocorticoid-induced osteoporosis
    ENDOCRINOLOGY
    
    L.C. Hofbauer et al., "Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential paracrine mechanisms of glucocorticoid-induced osteoporosis", ENDOCRINOL, 140(10), 1999, pp. 4382-4389
27. BOYLE WJ; HSU HL; PENNINGER J; DUNSTAN CR; SIMONET WS; LACEY DL
    REGULATION OF BONE-DENSITY VIA THE OPG, OPGL (RANKL), AND ODAR (RANK)TRIANGLE
    European cytokine network
    
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28. BUCAY N; SAROSI I; DUNSTAN CR; MORONY S; TARPLEY J; CAPPARELLI C; SCULLY S; TAN HL; XU WL; LACEY DL; BOYLE WJ; SIMONET WS
    OSTEOPROTEGERIN-DEFICIENT MICE DEVELOP EARLY-ONSET OSTEOPOROSIS AND ARTERIAL CALCIFICATION
    Genes & development
    
    N. Bucay et al., "OSTEOPROTEGERIN-DEFICIENT MICE DEVELOP EARLY-ONSET OSTEOPOROSIS AND ARTERIAL CALCIFICATION", Genes & development, 12(9), 1998, pp. 1260-1268
29. LACEY DL; TIMMS E; TAN HL; KELLEY MJ; DUNSTAN CR; BURGESS T; ELLIOTT R; COLOMBERO A; ELLIOTT G; SCULLY S; HSU H; SULLIVAN J; HAWKINS N; DAVY E; CAPPARELLI C; ELI A; QIAN YX; KAUFMAN S; SAROSI I; SHALHOUB V; SENALDI G; GUO J; DELANEY J; BOYLE WJ
    OSTEOPROTEGERIN LIGAND IS A CYTOKINE THAT REGULATES OSTEOCLAST DIFFERENTIATION AND ACTIVATION
    Cell
    
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30. ZUBERY Y; DUNSTAN CR; STORY BM; KESAVALU L; EBERSOLE JL; HOLT SC; BOYCE BF
    BONE-RESORPTION CAUSED BY 3 PERIODONTAL PATHOGENS IN-VIVO IN MICE IS MEDIATED IN PART BY PROSTAGLANDIN
    Infection and immunity
    
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31. HOFBAUER LC; DUNSTAN CR; SPELSBERG TC; RIGGS BL; KHOSLA S
    OSTEOPROTEGERIN PRODUCTION BY HUMAN OSTEOBLAST LINEAGE CELLS IS STIMULATED BY VITAMIN-D, BONE MORPHOGENETIC PROTEIN-2, AND CYTOKINES
    Biochemical and biophysical research communications (Print)
    
    L.C. Hofbauer et al., "OSTEOPROTEGERIN PRODUCTION BY HUMAN OSTEOBLAST LINEAGE CELLS IS STIMULATED BY VITAMIN-D, BONE MORPHOGENETIC PROTEIN-2, AND CYTOKINES", Biochemical and biophysical research communications (Print), 250(3), 1998, pp. 776-781
32. DUNSTAN CR; CAPPARELLI C; KELLEY M; SHIMAMOTO G; KAUFMAN S; RUSSELL D; CAMPAGNUOLO G; STARNES C; WIEMAN B; LACEY D
    OSTEOPROTEGERIN (OPG), A NOVEL TNF-RECEPTOR FAMILY MEMBER PROFOUNDLY INHIBITS ENDOSTEAL BONE-RESORPTION DUE TO GROWTH, HUMORAL HYPERCALCEMIA OF MALIGNANCY, AND INTERLEUKIN-1
    Journal of bone and mineral research
    
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33. CHEN D; HARRIS MA; ROSSINI G; DUNSTAN CR; DALLAS SL; FENG JQ; MUNDY GR; HARRIS SE
    BONE MORPHOGENETIC PROTEIN-2 (BMP-2) ENHANCES BMP-3, BMP-4, AND BONE CELL-DIFFERENTIATION MARKER GENE-EXPRESSION DURING THE INDUCTION OF MINERALIZED BONE-MATRIX FORMATION IN CULTURES OF FETAL-RAT CALVARIAL OSTEOBLASTS
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34. IZBICKA E; DUNSTAN CR; HORN D; ADAMS R; MUNDY GR
    MITOGENIC LECTIN CONCANAVALIN-A INDUCES CALVARIAL BONE-FORMATION IN-VIVO VIA INDOMETHACIN-SENSITIVE PATH NAY
    Calcified tissue international
    
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35. IZBICKA E; DUNSTAN CR; HORN D; HARRIS M; HARRIS S; ADAMS R; MUNDY GR
    EFFECTS OF HUMAN TUMOR-CELL LINES ON LOCAL NEW BONE-FORMATION IN-VIVO
    Calcified tissue international
    
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36. SIMONET WS; LACEY DL; DUNSTAN CR; KELLEY M; CHANG MS; LUTHY R; NGUYEN HQ; WOODEN S; BENNETT L; BOONE T; SHIMAMOTO G; DEROSE M; ELLIOTT R; COLOMBERO A; TAN HL; TRAIL G; SULLIVAN J; DAVY E; BUCAY N; RENSHAWGEGG L; HUGHES TM; HILL D; PATTISON W; CAMPBELL P; SANDER S; VAN G; TARPLEY J; DERBY P; LEE R; BOYLE WJ
    OSTEOPROTEGERIN - A NOVEL SECRETED PROTEIN INVOLVED IN THE REGULATIONOF BONE-DENSITY
    Cell
    
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37. UY HL; MUNDY GR; BOYCE BF; STORY BM; DUNSTAN CR; YIN JJ; ROODMAN GD; GUISE TA
    TUMOR-NECROSIS-FACTOR ENHANCES PARATHYROID HORMONE-RELATED PROTEIN-INDUCED HYPERCALCEMIA AND BONE-RESORPTION WITHOUT INHIBITING BONE-FORMATION IN-VIVO
    Cancer research
    
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38. MBALAVIELE G; DUNSTAN CR; SASAKI A; WILLIAMS PJ; MUNDY GR; YONEDA T
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39. DUNSTAN CR; GARRETT IR; ADAMS R; BURGESS W; JAYE M; YOUNGS T; BOYCE R; MUNDY GR
    SYSTEMIC FIBROBLAST GROWTH-FACTOR (FGF-1) PREVENTS BONE LOSS, INCREASES NEW BONE-FORMATION, AND RESTORES TRABECULAR MICROARCHITECTURE IN OVARIECTOMIZED RATS
    Journal of bone and mineral research
    
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40. CHEN D; ROSSINI G; FENG JQ; DUNSTAN CR; GHOSHCHOUDHURY N; DALLAS SJ; HARRIS MA; MUNDY GR; HARRIS SE
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41. GARCIA C; DALLAS M; BOYCE BF; DUNSTAN CR; MUNDY GR; BONEWALD LF
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42. GUTIERREZ G; GALLWITZ W; GARRETT IR; ROSSINI G; DUNSTAN CR; IZBICKA E; JACOBS C; BONEWALD L; ARNETT T; BURGESS W; MUNDY GR
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45. DUNSTAN CR; BOYCE BF; IZBICKA E; ADAMS R; MUNDY GR
    ACIDIC AND BASIC FIBROBLAST GROWTH-FACTORS PROMOTE BONE-GROWTH IN-VIVO COMPARABLE TO THAT OF TGF-BETA
    Journal of bone and mineral research
    
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46. WILLIAMS P; BOYCE BF; RHINE C; DUNSTAN CR; MUNDY GR; YONEDA T
    SURAMIN REDUCES CANCER-INDUCED HYPERCALCEMIA IN-VIVO AND BONE-RESORPTION IN-VITRO
    Journal of bone and mineral research
    
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47. DUNSTAN CR; SOMERS NM; EVANS RA; RUBIN; OTT; SNYDER; DAVY; SCHAFFLER; PARFITT; GOLDSTEIN
    OSTEOCYTE DEATH AND HIP FRACTURE
    Calcified tissue international
    
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