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1. Brabender, J; Lord, RV; Danenberg, KD; Metzger, R; Schneider, PM; Uetake, H; Kawakami, K; Park, JM; Salonga, D; Peters, JH; DeMeester, TR; Holscher, AH; Danenberg, PV
   Upregulation of ornithine decarboxylase mRNA expression in Barrett's esophagus and Barrett's - Associated adenocarcinoma
   JOURNAL OF GASTROINTESTINAL SURGERY
   
   J. Brabender et al., "Upregulation of ornithine decarboxylase mRNA expression in Barrett's esophagus and Barrett's - Associated adenocarcinoma", J GASTRO S, 5(2), 2001, pp. 174-181
2. Brabender, J; Danenberg, KD; Metzger, R; Schneider, PM; Park, JM; Salonga, D; Holscher, AH; Danenberg, PV
   Epidermal growth factor receptor and HER2-neu mRNA expression in non-smallcell lung cancer is correlated with survival
   CLINICAL CANCER RESEARCH
   
   J. Brabender et al., "Epidermal growth factor receptor and HER2-neu mRNA expression in non-smallcell lung cancer is correlated with survival", CLIN CANC R, 7(7), 2001, pp. 1850-1855
3. Grem, JL; Danenberg, KD; Behan, K; Parr, A; Young, L; Danenberg, PV; Nguyen, D; Drake, J; Monks, A; Allegra, CJ
   Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the national cancer institute's anticancer drugscreen
   CLINICAL CANCER RESEARCH
   
   J.L. Grem et al., "Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the national cancer institute's anticancer drugscreen", CLIN CANC R, 7(4), 2001, pp. 999-1009
4. Brabender, J; Usadel, H; Danenberg, KD; Metzger, R; Schneider, PM; Lord, RV; Wickramasinghe, K; Lum, CE; Park, J; Salonga, D; Singer, J; Sidransky, D; Holscher, AH; Meltzer, SJ; Danenberg, PV
   Adenomatous polyposis coli gene promoter hypermethylation in non-small cell lung cancer is associated with survival
   ONCOGENE
   
   J. Brabender et al., "Adenomatous polyposis coli gene promoter hypermethylation in non-small cell lung cancer is associated with survival", ONCOGENE, 20(27), 2001, pp. 3528-3532
5. Shirota, Y; Stoehlmacher, J; Brabender, J; Xiang, YP; Uetake, H; Danenberg, KD; Groshen, S; Tsao-Wei, DD; Danenberg, PV; Lenz, HJ
   ERCC1 and thymidylate synthase mRNA levels predict survival for colorectalcancer patients receiving combination oxaliplatin and fluorouracil chemotherapy
   JOURNAL OF CLINICAL ONCOLOGY
   
   Y. Shirota et al., "ERCC1 and thymidylate synthase mRNA levels predict survival for colorectalcancer patients receiving combination oxaliplatin and fluorouracil chemotherapy", J CL ONCOL, 19(23), 2001, pp. 4298-4304
6. Fu, CH; Martin-Aragon, S; Weinberg, KI; Ardi, VC; Danenberg, PV; Avramis, VI
   Reversal of cytosine arabinoside (ara-C) resistance by the synergistic combination of 6-thioguanine plus ara-C plus PEG-asparaginase (TGAP) in human leukemia lines lacking or expressing p53 protein
   CANCER CHEMOTHERAPY AND PHARMACOLOGY
   
   C.H. Fu et al., "Reversal of cytosine arabinoside (ara-C) resistance by the synergistic combination of 6-thioguanine plus ara-C plus PEG-asparaginase (TGAP) in human leukemia lines lacking or expressing p53 protein", CANC CHEMOT, 48(2), 2001, pp. 123-133
7. Lord, RVN; Tsai, PI; Danenberg, KD; Peters, JH; DeMeester, TR; Tsao-Wei, DD; Groshen, S; Salonga, D; Park, JM; Crookes, PF; Kiyabu, M; Chandrasoma, P; Danenberg, PV
   Retinoic acid receptor-alpha messenger RNA expression is increased and retinoic acid receptor-gamma expression is decreased in Barrett's intestinal metaplasia, dysplasia, adenocarcinoma sequence
   SURGERY
   
   R.V.N. Lord et al., "Retinoic acid receptor-alpha messenger RNA expression is increased and retinoic acid receptor-gamma expression is decreased in Barrett's intestinal metaplasia, dysplasia, adenocarcinoma sequence", SURGERY, 129(3), 2001, pp. 267-276
8. Brabender, J; Lord, RV; Danenberg, KD; Metzger, R; Schneider, PM; Park, JM; Salonga, D; Groshen, S; Tsao-Wei, DD; DeMeester, TR; Holscher, AH; Danenberg, PV
   Increased c-myb mRNA expression in Barrett's esophagus and Barrett's-associated adenocarcinoma
   JOURNAL OF SURGICAL RESEARCH
   
   J. Brabender et al., "Increased c-myb mRNA expression in Barrett's esophagus and Barrett's-associated adenocarcinoma", J SURG RES, 99(2), 2001, pp. 301-306
9. Lord, RVN; Salonga, D; Danenberg, KD; Peters, JH; DeMeester, TR; Park, M; Johansson, J; Skinner, KA; Chandrasoma, P; DeMeester, SR; Bremner, CG; Tsai, PI; Danenberg, PV
   Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence
   JOURNAL OF GASTROINTESTINAL SURGERY
   
   R.V.N. Lord et al., "Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence", J GASTRO S, 4(2), 2000, pp. 135-142
10. Salonga, D; Danenberg, KD; Johnson, M; Metzger, R; Groshen, S; Tsao-Wei, DD; Lenz, HJ; Leichman, CG; Leichman, L; Diasio, RB; Danenberg, PV
    Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase
    CLINICAL CANCER RESEARCH
    
    D. Salonga et al., "Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase", CLIN CANC R, 6(4), 2000, pp. 1322-1327
11. Lehman, NL; Danenberg, PV
    Modulation of RTX cytotoxicity by thymidine and dipyridamole in vitro: implications for chemotherapy
    CANCER CHEMOTHERAPY AND PHARMACOLOGY
    
    N.L. Lehman e P.V. Danenberg, "Modulation of RTX cytotoxicity by thymidine and dipyridamole in vitro: implications for chemotherapy", CANC CHEMOT, 45(2), 2000, pp. 142-148
12. Brabender, J; Lenz, HJ; Danenberg, PV
    Molecular marker as the basis for chemotherapy?
    CHIRURG
    
    J. Brabender et al., "Molecular marker as the basis for chemotherapy?", CHIRURG, 71(12), 2000, pp. 1433-1439
13. Banerjee, D; Gorlick, R; Liefshitz, A; Danenberg, K; Danenberg, PC; Danenberg, PV; Klimstra, D; Jhanwar, S; Cordon-Cardo, C; Fong, Y; Kemeny, N; Bertino, JR
    Levels of E2F-1 expression are higher in lung metastasis of colon cancer as compared with hepatic metastasis and correlate with levels of thymidylatesynthase
    CANCER RESEARCH
    
    D. Banerjee et al., "Levels of E2F-1 expression are higher in lung metastasis of colon cancer as compared with hepatic metastasis and correlate with levels of thymidylatesynthase", CANCER RES, 60(9), 2000, pp. 2365-2367
14. Eads, CA; Lord, RV; Kurumboor, SK; Wickramasinghe, K; Skinner, ML; Long, TI; Peters, JH; DeMeester, TR; Danenberg, KD; Danenberg, PV; Laird, PW; Skinner, KA
    Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma
    CANCER RESEARCH
    
    C.A. Eads et al., "Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma", CANCER RES, 60(18), 2000, pp. 5021-5026
15. Link, KH; Kornmann, M; Butzer, U; Leder, G; Sunelaitis, E; Pillasch, J; Salonga, D; Danenberg, KD; Danenberg, PV; Beger, HG
    Thymidylate synthase quantitation and in vitro chemosensitivity testing predicts responses and survival of patients with isolated nonresectable livertumors receiving hepatic arterial infusion chemotherapy
    CANCER
    
    K.H. Link et al., "Thymidylate synthase quantitation and in vitro chemosensitivity testing predicts responses and survival of patients with isolated nonresectable livertumors receiving hepatic arterial infusion chemotherapy", CANCER, 89(2), 2000, pp. 288-296
16. Sirotnak, FM; Danenberg, KD; Chen, J; Fritz, F; Danenberg, PV
    Markedly decreased binding of vincristine to tubulin in vinca alkaloid-resistant Chinese hamster cells is associated with selective overexpression ofalpha and beta tubulin isoforms
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    
    F.M. Sirotnak et al., "Markedly decreased binding of vincristine to tubulin in vinca alkaloid-resistant Chinese hamster cells is associated with selective overexpression ofalpha and beta tubulin isoforms", BIOC BIOP R, 269(1), 2000, pp. 21-24
17. Kawakami, K; Brabender, J; Lord, RV; Groshen, S; Greenwald, BD; Krasna, MJ; Yin, J; Fleisher, AS; Abraham, JM; Beer, DG; Sidransky, D; Huss, HT; Demeester, TR; Eads, C; Laird, PW; Ilson, DH; Kelsen, DP; Harpole, D; Moore, MB; Danenberg, KD; Danenberg, PV; Meltzer, SJ
    Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma
    JOURNAL OF THE NATIONAL CANCER INSTITUTE
    
    K. Kawakami et al., "Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma", J NAT CANC, 92(22), 2000, pp. 1805-1811
18. Abolhoda, A; Wilson, AE; Ross, H; Danenberg, PV; Burt, M; Scotto, KW
    Rapid activation of MDR1 gene expression in human metastatic sarcoma afterin vivo exposure to doxorubicin
    CLINICAL CANCER RESEARCH
    
    A. Abolhoda et al., "Rapid activation of MDR1 gene expression in human metastatic sarcoma afterin vivo exposure to doxorubicin", CLIN CANC R, 5(11), 1999, pp. 3352-3356
19. Formenti, SC; Symmans, WF; Volm, M; Skinner, K; Cohen, D; Spicer, D; Danenberg, PV
    Concurrent paclitaxel and radiation therapy for breast cancer
    SEMINARS IN RADIATION ONCOLOGY
    
    S.C. Formenti et al., "Concurrent paclitaxel and radiation therapy for breast cancer", SEM RAD ONC, 9(2), 1999, pp. 34-42
20. Danenberg, PV; Malli, H; Swenson, S
    Thymidylate synthase inhibitors
    SEMINARS IN ONCOLOGY
    
    P.V. Danenberg et al., "Thymidylate synthase inhibitors", SEMIN ONCOL, 26(6), 1999, pp. 621-631
21. Eads, CA; Danenberg, KD; Kawakami, K; Saltz, LB; Danenberg, PV; Laird, PW
    CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression. (vol 59, pg 2302, 1999)
    CANCER RESEARCH
    
    C.A. Eads et al., "CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression. (vol 59, pg 2302, 1999)", CANCER RES, 59(22), 1999, pp. 5860-5860
22. Kornmann, M; Danenberg, KD; Arber, N; Beger, HG; Danenberg, PV; Korc, M
    Inhibition of cyclin D1 expression in human pancreatic cancer cells is associated with increased chemosensitivity and decreased expression of multiple chemoresistance genes
    CANCER RESEARCH
    
    M. Kornmann et al., "Inhibition of cyclin D1 expression in human pancreatic cancer cells is associated with increased chemosensitivity and decreased expression of multiple chemoresistance genes", CANCER RES, 59(14), 1999, pp. 3505-3511
23. Eads, CA; Danenberg, KD; Kawakami, K; Saltz, LB; Danenberg, PV; Laird, PW
    CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression
    CANCER RESEARCH
    
    C.A. Eads et al., "CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression", CANCER RES, 59(10), 1999, pp. 2302-2306
24. JU JF; KANE SE; LENZ HJ; DANENBERG KD; CHU E; DANENBERG PV
    DESENSITIZATION AND SENSITIZATION OF CELLS TO FLUOROPYRIMIDINES WITH DIFFERENT ANTISENSES DIRECTED AGAINST THYMIDYLATE SYNTHASE MESSENGER-RNA
    Clinical cancer research
    
    J.F. Ju et al., "DESENSITIZATION AND SENSITIZATION OF CELLS TO FLUOROPYRIMIDINES WITH DIFFERENT ANTISENSES DIRECTED AGAINST THYMIDYLATE SYNTHASE MESSENGER-RNA", Clinical cancer research, 4(9), 1998, pp. 2229-2236
25. LENZ HJ; DANENBERG KD; LEICHMAN CG; FLORENTINE B; JOHNSTON PG; GROSHEN S; ZHOU LY; XIONG YP; DANENBERG PV; LEICHMAN LP
    P53 AND THYMIDYLATE SYNTHASE EXPRESSION IN UNTREATED STAGE-II COLON-CANCER - ASSOCIATIONS WITH RECURRENCE, SURVIVAL, AND SITE
    Clinical cancer research
    
    H.J. Lenz et al., "P53 AND THYMIDYLATE SYNTHASE EXPRESSION IN UNTREATED STAGE-II COLON-CANCER - ASSOCIATIONS WITH RECURRENCE, SURVIVAL, AND SITE", Clinical cancer research, 4(5), 1998, pp. 1227-1234
26. LENZ HJ; DANENBERG KD; LEICHMAN CG; FLORENTINE B; JOHNSTON PG; GROSHEN S; ZHOU LY; XIONG YP; DANENBERG PV; LEICHMAN LP
    P53 AND THYMIDYLATE SYNTHASE EXPRESSION IN UNTREATED STAGE-II COLON-CANCER - ASSOCIATIONS WITH RECURRENCE, SURVIVAL, AND SITE
    Clinical cancer research
    
    H.J. Lenz et al., "P53 AND THYMIDYLATE SYNTHASE EXPRESSION IN UNTREATED STAGE-II COLON-CANCER - ASSOCIATIONS WITH RECURRENCE, SURVIVAL, AND SITE", Clinical cancer research, 4(5), 1998, pp. 1227-1234
27. LENZ HJ; HAYASHI K; SALONGA D; DANENBERG KD; DANENBERG PV; METZGER R; BANERJEE D; BERTINO JR; GROSHEN S; LEICHMAN LP; LEICHMAN CG
    P53 POINT MUTATIONS AND THYMIDYLATE SYNTHASE MESSENGER-RNA LEVELS IN DISSEMINATED COLORECTAL-CANCER - AN ANALYSIS OF RESPONSE AND SURVIVAL
    Clinical cancer research
    
    H.J. Lenz et al., "P53 POINT MUTATIONS AND THYMIDYLATE SYNTHASE MESSENGER-RNA LEVELS IN DISSEMINATED COLORECTAL-CANCER - AN ANALYSIS OF RESPONSE AND SURVIVAL", Clinical cancer research, 4(5), 1998, pp. 1243-1250
28. LENZ HJ; HAYASHI K; SALONGA D; DANENBERG KD; DANENBERG PV; METZGER R; BANERJEE D; BERTINO JR; GROSHEN S; LEICHMAN LP; LEICHMAN CG
    P53 POINT MUTATIONS AND THYMIDYLATE SYNTHASE MESSENGER-RNA LEVELS IN DISSEMINATED COLORECTAL-CANCER - AN ANALYSIS OF RESPONSE AND SURVIVAL
    Clinical cancer research
    
    H.J. Lenz et al., "P53 POINT MUTATIONS AND THYMIDYLATE SYNTHASE MESSENGER-RNA LEVELS IN DISSEMINATED COLORECTAL-CANCER - AN ANALYSIS OF RESPONSE AND SURVIVAL", Clinical cancer research, 4(5), 1998, pp. 1243-1250
29. JU JF; BANERJEE D; LENZ HJ; DANENBERG KD; SCHMITTGEN TC; SPEARS CP; SCHONTHAL AH; MANNO DJ; HOCHHAUSER D; BERTINO JR; DANENBERG PV
    RESTORATION OF WILD-TYPE P53 ACTIVITY IN P53-NULL HL-60 CELLS CONFERSMULTIDRUG SENSITIVITY
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30. JU JF; BANERJEE D; LENZ HJ; DANENBERG KD; SCHMITTGEN TC; SPEARS CP; SCHONTHAL AH; MANNO DJ; HOCHHAUSER D; BERTINO JR; DANENBERG PV
    RESTORATION OF WILD-TYPE P53 ACTIVITY IN P53-NULL HL-60 CELLS CONFERSMULTIDRUG SENSITIVITY
    Clinical cancer research
    
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31. METZGER R; DANENBERG K; LEICHMAN CG; SALONGA D; SCHWARTZ EL; WADLER S; LENZ HJ; GROSHEN S; LEICHMAN L; DANENBERG PV
    HIGH BASAL LEVEL GENE-EXPRESSION OF THYMIDINE PHOSPHORYLASE (PLATELET-DERIVED ENDOTHELIAL-CELL GROWTH-FACTOR) IN COLORECTAL TUMORS IS ASSOCIATED WITH NONRESPONSE TO 5-FLUOROURACIL
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32. FORD HER; FARRUGIA DC; CUNNINGHAM D; MCVICAR D; MCCARTHY K; MITCHELL F; AHERNE GW; JACKMAN AL; DANENBERG K; LENZ HJ; DANENBERG PV
    A PHARMACODYNAMIC STUDY OF RALTITREXED (TOMUDEX(R)) IN PATIENTS WITH ADVANCED COLORECTAL-CANCER - PREDICTORS OF RESPONSE AND TOXICITY
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33. GORLICK R; METZGER R; DANENBERG KD; SALONGA D; MILES JS; LONGO GSA; FU J; BANERJEE D; KLIMSTRA D; JHANWAR S; DANENBERG PV; KEMENY N; BERTINO JR
    HIGHER LEVELS OF THYMIDYLATE SYNTHASE GENE-EXPRESSION ARE OBSERVED INPULMONARY AS COMPARED WITH HEPATIC METASTASES OF COLORECTAL ADENOCARCINOMA
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34. METZGER R; LEICHMAN CG; DANENBERG KD; DANENBERG PV; LENZ HJ; HAYASHI K; GROSHEN S; SALONGA D; COHEN H; LAINE L; CROOKES P; SILBERMAN H; BARANDA J; KONDA K; LEICHMAN L
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36. LEICHMAN CG; LENZ HJ; LEICHMAN L; DANENBERG K; BARANDA J; GROSHEN S; BOSWELL W; METZGER R; TAN M; DANENBERG PV
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    THYMIDYLATE SYNTHASE IS A PREDICTOR FOR RESPONSE AND RESISTANCE IN HEPATIC-ARTERY INFUSION CHEMOTHERAPY
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40. SHUIN T; TORIGOE S; KUBOTA Y; KISHIDA T; HOSAKA M; HORIKOSHI T; YAO M; KONDO K; SAKAI N; DANENBERG K; DANENBERG PV
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42. KUBOTA Y; SHUIN T; UEMURA H; FUJINAMI K; MIYAMOTO H; TORIGOE S; DOBASHI Y; KITAMURA H; IWASAKI Y; DANENBERG K; DANENBERG PV
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43. WANG SJ; SCAVETTA R; LENZ HJ; DANENBERG K; DANENBERG PV; SCHONTHAL AH
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44. SCHMITTGEN TD; DANENBERG KD; HORIKOSHI T; LENZ HJ; DANENBERG PV
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45. JOHNSTON PG; LENZ HJ; LEICHMAN CG; DANENBERG KD; ALLEGRA CJ; DANENBERG PV; LEICHMAN L
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46. LENZ HJ; DANENBERG K; SCHNIEDERS B; GOEKER E; PETERS GJ; GARROW T; SHANE B; BERTINO JR; DANENBERG PV
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