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    1. Pitts, JD; Sloboda, RD; Dragnev, KH; Dmitrovsky, E; Mycek, MA
      Autofluorescence characteristics of immortalized and carcinogen-transformed human bronchial epithelial cells

      JOURNAL OF BIOMEDICAL OPTICS
    2. Boyle, JO; Lonardo, F; Chang, JH; Klimstra, D; Rusch, V; Dmitrovsky, E
      Multiple high-grade bronchial dysplasia and squamous cell carcinoma: Concordant and discordant mutations

      CLINICAL CANCER RESEARCH
    3. Curtin, JC; Dragnev, KH; Sekula, D; Christie, AJ; Dmitrovsky, E; Spinella, MJ
      Retinoic acid activates p53 in human embryonal carcinoma through retinoid receptor-dependent stimulation of p53 transactivation function

      ONCOGENE
    4. Spinella, MJ; Dmitrovsky, E
      Aerosolized delivery and lung cancer prevention: Pre-clinical models show promise

      CLINICAL CANCER RESEARCH
    5. Spinella, MJ; Dmitrovsky, E
      Aberrant retinoid signaling and breast cancer: the view from outside the nucleus

      JOURNAL OF THE NATIONAL CANCER INSTITUTE
    6. Kitareewan, S; Spinella, MJ; Allopenna, J; Reczek, PR; Dmitrovsky, E
      4HPR triggers apoptosis but not differentiation in retinoid sensitive and resistant human embryonal carcinoma cells through an RAR gamma independent pathway

      ONCOGENE
    7. Yeyati, PL; Shaknovich, R; Boterashvili, S; Li, J; Ball, HJ; Waxman, S; Nason-Burchenal, K; Dmitrovsky, E; Zelent, A; Licht, JD
      Leukemia translocation protein PLZF inhibits cell growth and expression ofcyclin A

      ONCOGENE
    8. Hromas, R; Ye, HG; Spinella, M; Dmitrovsky, E; Xu, DW; Costa, RH
      Genesis, a Winged Helix transcriptional repressor, has embryonic expression limited to the neural crest, and stimulates proliferation in vitro in a neural development model

      CELL AND TISSUE RESEARCH
    9. Tamayo, P; Slonim, D; Mesirov, J; Zhu, Q; Kitareewan, S; Dmitrovsky, E; Lander, ES; Golub, TR
      Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    10. Spinella, MJ; Freemantle, SJ; Sekula, D; Chang, JH; Christie, AJ; Dmitrovsky, E
      Retinoic acid promotes ubiquitination and proteolysis of cyclin D1 during induced tumor cell differentiation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    11. Suh, NJ; Wang, YP; Honda, T; Gribble, GW; Dmitrovsky, E; Hickey, WF; Maue, RA; Place, AE; Porter, DM; Spinella, MJ; Williams, CR; Wu, GF; Dannenberg, AJ; Flanders, KC; Letterio, JJ; Mangelsdorf, DJ; Nathan, CF; Nguyen, L; Porter, WW; Ren, RF; Roberts, AB; Roche, NS; Subbaramaiah, K; Sporn, MB
      A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity

      CANCER RESEARCH
    12. Lonardo, F; Rusch, V; Langenfeld, J; Dmitrovsky, E; Klimstra, S
      Overexpression of cyclins D1 and E is frequent in bronchial preneoplasia and precedes squamous cell carcinoma development

      CANCER RESEARCH
    13. Boyle, JO; Langenfeld, J; Lonardo, F; Sekula, D; Reczek, P; Rusch, V; Dawson, MI; Dmitrovsky, E
      Cyclin D1 proteolysis: A retinoid chemoprevention signal in normal, immortalized, and transformed human bronchial epithelial cells

      JOURNAL OF THE NATIONAL CANCER INSTITUTE
    14. Albanell, J; Bosl, GJ; Reuter, VE; Engelhardt, M; Franco, S; Moore, MAS; Dmitrovsky, E
      Telomerase activity in germ cell cancers and mature teratomas

      JOURNAL OF THE NATIONAL CANCER INSTITUTE
    15. MAERZ WJ; BASELGA J; REUTER VE; MELLADO B; MYERS ML; BOSL GJ; SPINELLA MJ; DMITROVSKY E
      FGF4 DISSOCIATES ANTI-TUMORIGENIC FROM DIFFERENTIATION SIGNALS OF RETINOIC ACID IN HUMAN EMBRYONAL CARCINOMAS

      Oncogene
    16. NASONBURCHENAL K; TAKLE G; PACE U; FLYNN S; ALLOPENNA J; MARTIN P; GEORGE ST; GOLDBERG AR; DMITROVSKY E
      TARGETING THE PML RAR-ALPHA TRANSLOCATION PRODUCT TRIGGERS APOPTOSIS IN PROMYELOCYTIC LEUKEMIA-CELLS/

      Oncogene
    17. SPINELLA MJ; KITAREEWAN S; MELLADO B; SEKULA D; KHOO KS; DMITROVSKY E
      SPECIFIC RETINOID RECEPTORS COOPERATE TO SIGNAL GROWTH SUPPRESSION AND MATURATION OF HUMAN EMBRYONAL CARCINOMA-CELLS

      Oncogene
    18. PASCHE B; LUO Y; RAO PH; NIMER SD; DMITROVSKY E; CARON P; LUZZATTO L; OFFIT K; CORDONCARDO C; RENAULT B; SATAGOPAN JM; MURTY VVVS; MASSAGUE J
      TYPE-I TRANSFORMING-GROWTH-FACTOR-BETA RECEPTOR MAPS TO 9Q22 AND EXHIBITS A POLYMORPHISM AND A RARE VARIANT WITHIN A POLYALANINE TRACT

      Cancer research
    19. NASONBURCHENAL K; ALLOPENNA J; BEGUE A; STEHELIN D; DMITROVSKY E; MARTIN P
      TARGETING OF PML RAR-ALPHA IS LETHAL TO RETINOIC ACID-RESISTANT PROMYELOCYTIC LEUKEMIA-CELLS/

      Blood
    20. RUSCH V; KLIMSTRA D; VENKATRAMAN E; PISTERS PWT; LANGENFELD J; DMITROVSKY E
      OVEREXPRESSION OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR AND ITS LIGANDTRANSFORMING-GROWTH-FACTOR-ALPHA IS FREQUENT IN RESECTABLE NONSMALL CELL LUNG-CANCER BUT DOES NOT PREDICT TUMOR PROGRESSION

      Clinical cancer research
    21. LEI W; HIROSE T; ZHANG LX; ADACHI H; SPINELLA MJ; DMITROVSKY E; JETTEN AM
      CLONING OF THE HUMAN ORPHAN RECEPTOR GERM-CELL NUCLEAR FACTOR RETINOID RECEPTOR-1-RELATED TESTIS-ASSOCIATED RECEPTOR AND ITS DIFFERENTIAL REGULATION DURING EMBRYONAL CARCINOMA CELL-DIFFERENTIATION

      Journal of molecular endocrinology
    22. NASONBURCHENAL K; MAERZ W; ALBANELL J; ALLOPENNA J; MARTIN P; MOORE MAS; DMITROVSKY E
      COMMON DEFECTS OF DIFFERENT RETINOIC ACID-RESISTANT PROMYELOCYTIC LEUKEMIA-CELLS ARE PERSISTENT TELOMERASE ACTIVITY AND NUCLEAR-BODY DISORGANIZATION

      Differentiation
    23. LANGENFELD J; KIYOKAWA H; SEKULA D; BOYLE J; DMITROVSKY E
      POSTTRANSLATIONAL REGULATION OF CYCLIN D1 BY RETINOIC ACID - A CHEMOPREVENTION MECHANISM

      Proceedings of the National Academy of Sciences of the United Statesof America
    24. LONARDO F; LANGENFELD J; DMITROVSKY E; RUSCH V; KLIMSTRA DS
      COMPARATIVE PATTERNS OF EXPRESSION OF CYCLIN D1, P53 AND RB IN BRONCHIAL PRENEOPLASTIC LESIONS

      Laboratory investigation
    25. DMITROVSKY E; MOORE MAS
      PML-RAR-ALPHA AND N-RAS SYNERGIZE TO PROMOTE PROLIFERATION OF MYELOMONOCYTIC CELLS

      Blood
    26. ALBANELL J; LONARDO F; RUSCH V; ENGELHARDT M; LANGENFELD J; HAN W; KLIMSTRA D; VENKATRAMAN E; MOORE MAS; DMITROVSKY E
      HIGH TELOMERASE ACTIVITY IN PRIMARY LUNG CANCERS - ASSOCIATION WITH INCREASED CELL-PROLIFERATION RATES AND ADVANCED PATHOLOGICAL STAGE

      Journal of the National Cancer Institute
    27. DMITROVSKY E
      N-(4-HYDROXYPHENYL)RETINAMIDE ACTIVATION OF A DISTINCT PATHWAY SIGNALING APOPTOSIS

      Journal of the National Cancer Institute
    28. HOFFMAN AD; ENGELSTEIN D; BOGENRIEDER T; PAPANDREOU CN; STECKELMAN E; DAVE A; MOTZER RJ; DMITROVSKY E; ALBINO AP; NANUS DM
      EXPRESSION OF RETINOIC ACID RECEPTOR-BETA IN HUMAN RENAL-CELL CARCINOMAS CORRELATES WITH SENSITIVITY TO THE ANTIPROLIFERATIVE EFFECTS OF 13-CIS-RETINOIC ACID

      Clinical cancer research
    29. LANGENFELD J; LONARDO F; KIYOKAWA H; PASSALARIS T; AHN MJ; RUSCH V; DMITROVSKY E
      INHIBITED TRANSFORMATION OF IMMORTALIZED HUMAN BRONCHIAL EPITHELIAL-CELLS BY RETINOIC ACID IS LINKED TO CYCLIN-E DOWN-REGULATION

      Oncogene
    30. MOASSER MM; KHOO KS; MAERZ WJ; ZELENETZ A; DMITROVSKY E
      DERIVATION AND CHARACTERIZATION OF RETINOID-RESISTANT HUMAN EMBRYONALCARCINOMA-CELLS

      Differentiation
    31. EARLY E; MOORE MAS; KAKIZUKA A; NASONBURCHENAL K; MARTIN P; EVANS RM; DMITROVSKY E
      TRANSGENIC EXPRESSION OF PML RAR-ALPHA IMPAIRS MYELOPOIESIS/

      Proceedings of the National Academy of Sciences of the United Statesof America
    32. BALDASSARRE G; BIANCO C; TORTORA G; RUGGIERO A; MOASSER M; DMITROVSKY E; BIANCO AR; CIARDIELLO F
      TRANSFECTION WITH A CRIPTO ANTISENSE PLASMID SUPPRESSES ENDOGENOUS CRIPTO EXPRESSION AND INHIBITS TRANSFORMATION IN A HUMAN EMBRYONAL CARCINOMA CELL-LINE

      International journal of cancer
    33. ALBANELL J; HAN W; MELLADO B; GUNAWARDANE R; SCHER HI; DMITROVSKY E; MOORE MAS
      TELOMERASE ACTIVITY IS REPRESSED DURING DIFFERENTIATION OF MATURATION-SENSITIVE BUT NOT RESISTANT HUMAN TUMOR-CELL LINES

      Cancer research
    34. SHAKNOVICH R; YEYATI PL; WAXMAN S; HELLINGER N; NASONBURCHENAL K; DMITROVSKY E; STRUTT P; ZELENT A; LICHT JD
      THE PROMYELOCYTIC LEUKEMIA ZINC-FINGER PROTEIN (PLZF) SUPPRESSES GROWTH AND INDUCES APOPTOSIS IN THE 32DCL3 MYELOID CELL-LINE

      Blood
    35. NASONBURCHENAL K; GANDINI D; BOTTO M; ALLOPENNA J; SEALE JRC; CROSS NCP; GOLDMAN JM; DMITROVSKY E; PANDOLFI PP
      INTERFERON AUGMENTS PML AND PML RAR-ALPHA EXPRESSION IN NORMAL MYELOID AND ACUTE PROMYELOCYTIC CELLS AND COOPERATES WITH ALL-TRANS-RETINOICACID TO INDUCE MATURATION OF A RETINOID-RESISTANT PROMYELOCYTIC CELL-LINE/

      Blood
    36. EARLY E; DMITROVSKY E
      ACUTE PROMYELOCYTIC LEUKEMIA - RETINOIC ACID RESPONSE AND RESISTANCE

      Journal of investigative medicine
    37. AHN MJ; LANGENFELD J; MOASSER MM; RUSCH V; DMITROVSKY E
      GROWTH SUPPRESSION OF TRANSFORMED HUMAN BRONCHIAL EPITHELIAL-CELLS BYALL-TRANS-RETINOIC ACID OCCURS THROUGH SPECIFIC RETINOID RECEPTORS

      Oncogene
    38. MOASSER MM; REUTER VE; DMITROVSKY E
      OVEREXPRESSION OF THE RETINOIC ACID RECEPTOR-GAMMA DIRECTLY INDUCES TERMINAL DIFFERENTIATION OF HUMAN EMBRYONAL CARCINOMA-CELLS

      Oncogene
    39. AHN MJ; NASONBURCHENAL K; MOASSER MM; DMITROVSKY E
      GROWTH SUPPRESSION OF ACUTE PROMYELOCYTIC LEUKEMIA-CELLS HAVING INCREASED EXPRESSION OF THE NONREARRANGED ALLELES - RAR-ALPHA OR PML

      Oncogene
    40. RUSCH V; KLIMSTRA D; LINKOV I; DMITROVSKY E
      ABERRANT EXPRESSION OF P53 OR THE EPIDERMAL GROWTH-FACTOR RECEPTOR ISFREQUENT IN EARLY BRONCHIAL NEOPLASIA, AND COEXPRESSION PRECEDES SQUAMOUS-CELL CARCINOMA DEVELOPMENT

      Cancer research
    41. RUSCH V; KLIMSTRA D; VENKATRAMAN E; OLIVER J; MARTINI N; GRALLA R; KRIS M; DMITROVSKY E
      ABERRANT P53 EXPRESSION PREDICTS CLINICAL RESISTANCE TO CISPLATIN-BASED CHEMOTHERAPY IN LOCALLY ADVANCED NON-SMALL-CELL LUNG-CANCER

      Cancer research
    42. MOASSER MM; MOTZER RJ; KHOO KS; LYN P; MURPHY BA; BOSL GJ; DMITROVSKY E
      ALL-TRANS-RETINOIC ACID FOR TREATING GERM-CELL TUMORS - IN-VITRO ACTIVITY AND RESULTS OF A PHASE-II TRIAL

      Cancer
    43. NASONBURCHENAL K; GANDINI D; BOTTO M; ALLOPENNA J; SEALE JRC; CROSS NCP; GOLDMAN JM; DMITROVSKY E; PANDOLFI PP
      INTERFERON AUGMENTS PML AND PML RAR-ALPHA EXPRESSION IN NORMAL MYELOID AND ACUTE PROMYELOCYTIC CELLS AND COOPERATES WITH ALL-TRANS-RETINOICACID TO INDUCE MATURATION OF A RETINOID RESISTANT PROMYELOCYTIC CELL-LINE/

      Blood
    44. NASONBURCHENAL K; PACE U; TAKLE G; FLYNN S; ALLOPENNA J; MARTIN P; GEORGE ST; GOLDBERG AR; DMITROVSKY E
      OVER-EXPRESSION OF RIBOZYMES CLEAVING PML RAR-ALPHA IN-VITRO IS CYTOTOXIC TO ACUTE PROMYELOCYTIC LEUKEMIA-CELLS IN-VIVO/

      Blood
    45. MOASSER MM; DEBLASIO A; DMITROVSKY E
      RESPONSE AND RESISTANCE TO RETINOIC ACID ARE MEDIATED THROUGH THE RETINOIC ACID NUCLEAR RECEPTOR-GAMMA IN HUMAN TERATOCARCINOMAS

      Oncogene
    46. MILLER WH; MAERZ WJ; KURIE J; MOY D; BASELGA J; LUCAS DA; GRIPPO JF; MASUI H; DMITROVSKY E
      ALL-TRANS-RETINOIC ACID AND HEXAMETHYLENE BISACETAMIDE (HMBA) REGULATE TGF-ALPHA AND HST-1 KFGF EXPRESSION IN DIFFERENTIATION SENSITIVE BUTNOT IN RESISTANT HUMAN TERATOCARCINOMAS/

      Differentiation
    47. KURIE JM; ALLOPENNA J; DMITROVSKY E
      RETINOIC ACID STIMULATES PROTEIN-KINASE A-ASSOCIATED G-PROTEINS DURING HUMAN TERATOCARCINOMA DIFFERENTIATION

      Biochimica et biophysica acta. Molecular cell research
    48. PACE U; BOCKMAN JM; MACKAY BJ; MILLER WH; DMITROVSKY E; GOLDBERG AR
      A RIBOZYME WHICH DISCRIMINATES IN-VITRO BETWEEN PML RAR-ALPHA, THE T(15-17)-ASSOCIATED FUSION RNA OF ACUTE PROMYELOCYTIC LEUKEMIA, AND PML AND RAR-ALPHA, THE TRANSCRIPTS FROM THE NONREARRANGED ALLELES/

      Cancer research
    49. FRANKEL SR; EARDLEY A; HELLER G; BERMAN E; MILLER WH; DMITROVSKY E; WARRELL RP
      ALL-TRANS-RETINOIC ACID FOR ACUTE PROMYELOCYTIC LEUKEMIA - RESULTS OFTHE NEW-YORK STUDY

      Annals of internal medicine
    50. BASELGA J; MAERZ WJ; MOY D; MILLER WH; CASTRO L; REUTER VE; YAO TJ; MASUI H; DMITROVSKY E
      OVER-EXPRESSION OF TRANSFORMING GROWTH-FACTOR-ALPHA ANTAGONIZES THE ANTI-TUMORIGENIC BUT NOT THE DIFFERENTIATION ACTIONS OF RETINOIC ACID IN A HUMAN TERATOCARCINOMA CELL

      Oncogene
    51. KURIE JM; BROWN P; SALK E; SCHEINBERG D; BIRRER M; DEUTSCH P; DMITROVSKY E
      COOPERATION BETWEEN RETINOIC ACID AND PHORBOL ESTERS ENHANCES HUMAN TERATOCARCINOMA DIFFERENTIATION

      Differentiation
    52. KURIE JM; BUCK J; EPPINGER TM; MOY D; DMITROVSKY E
      9-CIS AND ALL-TRANS-RETINOIC ACID INDUCE A SIMILAR PHENOTYPE IN HUMANTERATOCARCINOMA CELLS

      Differentiation
    53. RUSCH V; BASELGA J; CORDONCARDO C; ORAZEM J; ZAMAN M; HODA S; MCINTOSH J; KURIE J; DMITROVSKY E
      DIFFERENTIAL EXPRESSION OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR AND ITS LIGANDS IN PRIMARY NONSMALL CELL LUNG CANCERS AND ADJACENT BENIGN LUNG

      Cancer research
    54. MOTZER RJ; DMITROVSKY E; MILLER WH; TONG WP; BAJORIN DF; SCHER HI; BOSL GJ
      SURAMIN FOR GERM-CELL TUMORS - IN-VITRO GROWTH-INHIBITION AND RESULTSOF A PHASE-II TRIAL

      Cancer
    55. MILLER WH; LEVINE K; DEBLASIO A; FRANKEL SR; DMITROVSKY E; WARRELL RP
      DETECTION OF MINIMAL RESIDUAL DISEASE IN ACUTE PROMYELOCYTIC LEUKEMIABY A REVERSE TRANSCRIPTION-POLYMERASE CHAIN-REACTION ASSAY FOR THE PML RAR-ALPHA FUSION MESSENGER-RNA

      Blood
    56. KURIE JM; YOUNES A; MILLER WH; BURCHERT M; CHIU CF; KOLESNICK R; DMITROVSKY E
      RETINOIC ACID STIMULATES THE PROTEIN-KINASE-C PATHWAY BEFORE ACTIVATION OF ITS BETA-NUCLEAR RECEPTOR DURING HUMAN TERATOCARCINOMA DIFFERENTIATION

      Biochimica et biophysica acta
    57. XIAO YH; MILLER WH; WARRELL RP; DMITROVSKY E; ZELENETZ AD
      PULSED-FIELD GEL-ELECTROPHORESIS ANALYSIS OF RETINOIC ACID RECEPTOR-ALPHA AND PROMYELOCYTIC LEUKEMIA REARRANGEMENTS - DETECTION OF THE T(1517) TRANSLOCATION IN THE DIAGNOSIS OF ACUTE PROMYELOCYTIC LEUKEMIA

      The American journal of pathology
    58. MILLER WH; KAKIZUKA A; FRANKEL SR; WARRELL RP; DEBLASIO A; LEVINE K; EVANS RM; DMITROVSKY E
      REVERSE TRANSCRIPTION POLYMERASE CHAIN-REACTION FOR THE REARRANGED RETINOIC ACID RECEPTOR-ALPHA CLARIFIES DIAGNOSIS AND DETECTS MINIMAL RESIDUAL DISEASE IN ACUTE PROMYELOCYTIC LEUKEMIA

      Proceedings of the National Academy of Sciences of the United Statesof America


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Documento generato il 25/01/21 alle ore 19:44:18