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    1. Diasio, RB
      Current status of oral chemotherapy for colorectal cancer

      ONCOLOGY-NEW YORK
    2. Heslin, MJ; Yan, J; Johnson, MR; Weiss, H; Diasio, RB; Urist, MM
      Role of matrix metalloproteinases in colorectal carcinogenesis

      ANNALS OF SURGERY
    3. Salonga, D; Danenberg, KD; Johnson, M; Metzger, R; Groshen, S; Tsao-Wei, DD; Lenz, HJ; Leichman, CG; Leichman, L; Diasio, RB; Danenberg, PV
      Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase

      CLINICAL CANCER RESEARCH
    4. Diasio, RB
      Oral DPD-inhibitory fluoropyrimidine drugs

      ONCOLOGY-NEW YORK
    5. Baker, SD; Diasio, RB; O'Reilly, S; Lucas, VS; Khor, SP; Sartorius, SE; Donehower, RC; Grochow, LB; Spector, T; Hohneker, JA; Rowinsky, EK
      Phase I and pharmacologic study of oral fluorouracil on a chronic daily schedule in combination with the dihydropyrimidine dehydrogenase inactivator eniluracil

      JOURNAL OF CLINICAL ONCOLOGY
    6. Shestopal, SA; Johnson, MR; Diasio, RB
      Molecular cloning and characterization of the human dihydropyrimidine dehydrogenase promoter

      BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
    7. Diasio, RB; Johnson, MR
      The role of pharmacogenetics and pharmacogenomics in cancer chemotherapy with 5-fluorouracil

      PHARMACOLOGY
    8. Chen, L; Smith, L; Johnson, MR; Wang, KS; Diasio, RB; Smith, JB
      Activation of protein kinase C induces nuclear translocation of RFX1 and down-regulates c-myc via an intron 1 X box in undifferentiated leukemia HL-60 cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    9. Johnson, MR; Wang, KS; Smith, JB; Heslin, MJ; Diasio, RB
      Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction

      ANALYTICAL BIOCHEMISTRY
    10. Johnson, MR; Hageboutros, A; Wang, KS; High, L; Smith, JB; Diasio, RB
      Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil

      CLINICAL CANCER RESEARCH
    11. Diasio, RB; Johnson, MR
      Dihydropyrimidine dehydrogenase: Its role in 5-fluorouracil clinical toxicity and tumor resistance

      CLINICAL CANCER RESEARCH
    12. Diasio, RB
      Clinical implications of dihydropyrimidine dehydrogenase inhibition

      ONCOLOGY-NEW YORK
    13. Diasio, RB
      Improving fluorouracil chemotherapy with novel orally administered fluoropyrimidines

      DRUGS
    14. LU ZH; ZHANG RW; CARPENTER JT; DIASIO RB
      DECREASED DIHYDROPYRIMIDINE DEHYDROGENASE-ACTIVITY IN A POPULATION OFPATIENTS WITH BREAST-CANCER - IMPLICATION FOR 5-FLUOROURACIL-BASED CHEMOTHERAPY

      Clinical cancer research
    15. LU ZH; ZHANG RW; CARPENTER JT; DIASIO RB
      DECREASED DIHYDROPYRIMIDINE DEHYDROGENASE-ACTIVITY IN A POPULATION OFPATIENTS WITH BREAST-CANCER - IMPLICATION FOR 5-FLUOROURACIL-BASED CHEMOTHERAPY

      Clinical cancer research
    16. McLeod, HL; Collie-Duguid, ESR; Vreken, P; Johnson, MR; Wei, X; Sapone, A; Diasio, RB; Fernandez-Salguero, P; van Kuilenberg, ABP; van Gennip, AH; Gonzalez, FJ
      Nomenclature for human DPYD alleles

      PHARMACOGENETICS
    17. DIASIO RB
      IMPROVING 5-FU WITH A NOVEL DIHYDROPYRIMIDINE DEHYDROGENASE INACTIVATOR

      Oncology
    18. DIASIO RB
      THE ROLE OF DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) MODULATION IN 5-FU PHARMACOLOGY

      Oncology
    19. DIASIO RB
      SORIVUDINE AND 5-FLUOROURACIL - A CLINICALLY SIGNIFICANT DRUG-DRUG INTERACTION DUE TO INHIBITION OF DIHYDROPYRIMIDINE DEHYDROGENASE

      British journal of clinical pharmacology
    20. DIASIO RB; LU Z; ZHANG R
      DECREASED DIHYDROPYRIMIDINE DEHYDROGENASE-ACTIVITY IN BREAST-CANCER

      Clinical pharmacology and therapeutics
    21. YAN J; SHAO L; WALSH GM; OMURA GA; SALEH M; DUVIC M; LING M; DIASIO RB
      INITIAL MULTIPLE-DOSE PHARMACOKINETICS OF ORAL-ADMINISTRATION OF BCX-34

      Clinical pharmacology and therapeutics
    22. JOHNSON MR; YAN JM; SHAO LN; ALBIN N; DIASIO RB
      SEMIAUTOMATED RADIOASSAY FOR DETERMINATION OF DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) ACTIVITY - SCREENING CANCER-PATIENTS FOR DPD DEFICIENCY, A CONDITION ASSOCIATED WITH 5-FLUOROURACIL TOXICITY

      Journal of chromatography B. Biomedical sciences and applications
    23. YAN JM; LU ZH; WALSH GM; WHEELER RH; DIASIO RB
      HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF 9-(3-PYRIDYLMETHYL)-9-DEAZAGUANINE (BCX-34) IN BIOLOGICAL-FLUIDS

      Journal of chromatography B. Biomedical sciences and applications
    24. DIASIO RB; ZHANG RW
      PHARMACOLOGY OF THERAPEUTIC OLIGONUCLEOTIDES

      ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT
    25. JIANG WQ; LU ZH; HE YJ; DIASIO RB
      DIHYDROPYRIMIDINE DEHYDROGENASE-ACTIVITY IN HEPATOCELLULAR-CARCINOMA - IMPLICATION IN 5-FLUOROURACIL-BASED CHEMOTHERAPY

      Clinical cancer research
    26. YAN JM; TYRING SK; MCCRARY MM; LEE PC; HAWORTH S; RAYMOND R; OLSEN SJ; DIASIO RB
      THE EFFECT OF SORIVUDINE ON DIHYDROPYRIMIDINE DEHYDROGENASE-ACTIVITY IN PATIENTS WITH ACUTE HERPES-ZOSTER

      Clinical pharmacology and therapeutics
    27. JOHNSON MR; WANG KS; TILLMANNS S; ALBIN N; DIASIO RB
      STRUCTURAL ORGANIZATION OF THE HUMAN DIHYDROPYRIMIDINE DEHYDROGENASE GENE

      Cancer research
    28. DIASIO RB; JOHNSON MR; ALBIN N
      MUTATIONS AT CODON-974 OF THE DPYD GENE ARE A RARE EVENT

      British Journal of Cancer
    29. TAKIMOTO CH; LU ZH; ZHANG RW; LIANG MD; LARSON LV; CANTILENA LR; GREM JL; ALLEGRA CJ; DIASIO RB; CHU E
      SEVERE NEUROTOXICITY FOLLOWING 5-FLUOROURACIL-BASED CHEMOTHERAPY IN APATIENT WITH DIHYDROPYRIMIDINE DEHYDROGENASE-DEFICIENCY

      Clinical cancer research
    30. ALBIN N; JOHNSON MR; DIASIO RB
      CDNA CLONING OF BOVINE LIVER DIHYDROPYRIMIDINE DEHYDROGENASE

      DNA sequence
    31. SALEH MN; DIASIO RB; SAMS WM; WHEELER RH; GREGG X; OMURA GA; WALSH GM
      PHASE-I EVALUATION OF ORAL BCX-34 (PELDESINE) IN CUTANEOUS T-CELL LYMPHOMA (CTCL)

      Blood
    32. ZHAO H; LU Z; DIASIO RB; AGRAWAL S; ZHANG R
      BILIARY-EXCRETION OF OLIGONUCLEOTIDES - PREVIOUSLY UNRECOGNIZED PATHWAY IN METABOLISM OF ANTISENSE OLIGONUCLEOTIDES

      The FASEB journal
    33. GANDARA DR; NAHHAS WA; ADELSON MD; LICHTMAN SM; PODCZASKI ES; YANOVICH S; HOMESLEY HD; BRALY P; RITCH PS; WEISBERG SR; WILLIAMS L; DIASIO RB; PEREZ EA; KARP D; REICH SD; MCCARROLL K; HOFF JV
      RANDOMIZED PLACEBO-CONTROLLED MULTICENTER EVALUATION OF DIETHYLDITHIOCARBAMATE FOR CHEMOPROTECTION AGAINST CISPLATIN-INDUCED TOXICITIES

      Journal of clinical oncology
    34. LU ZH; ZHANG RW; DIASIO RB
      POPULATION CHARACTERISTICS OF HEPATIC DIHYDROPYRIMIDINE DEHYDROGENASE-ACTIVITY, A KEY METABOLIC ENZYME IN 5-FLUOROURACIL CHEMOTHERAPY

      Clinical pharmacology and therapeutics
    35. ZHANG RW; YAN JM; SHAHINIAN H; AMIN G; LU ZH; LIU TP; SAAG MS; JIANG ZW; TEMSAMANI J; MARTIN RR; SCHECHTER PJ; AGRAWAL S; DIASIO RB
      PHARMACOKINETICS OF AN ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS ANTISENSE OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE (GEM-91) IN HIV-INFECTED SUBJECTS

      Clinical pharmacology and therapeutics
    36. ZHANG RW; LU ZH; ZHANG XS; ZHAO H; DIASIO RB; LIU TP; JIANG ZW; AGRAWAL S
      IN-VIVO STABILITY AND DISPOSITION OF A SELF-STABILIZED OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE IN RATS

      Clinical chemistry
    37. ZHANG RW; LU ZH; ZHAO H; ZHANG XS; DIASIO RB; HABUS I; JIANG ZW; IYER RP; YU D; AGRAWAL S
      IN-VIVO STABILITY, DISPOSITION AND METABOLISM OF A HYBRID OLIGONUCLEOTIDE PHOSPHOROTHIOATE IN RATS

      Biochemical pharmacology
    38. AGRAWAL S; ZHANG XS; LU ZH; ZHAO H; TAMBURIN JM; YAN YM; CAI HY; DIASIO RB; HABUS I; JIANG ZW; IYER RP; YU D; ZHANG RW
      ABSORPTION, TISSUE DISTRIBUTION AND IN-VIVO STABILITY IN RATS OF A HYBRID ANTISENSE OLIGONUCLEOTIDE FOLLOWING ORAL-ADMINISTRATION

      Biochemical pharmacology
    39. ZHANG RW; DIASIO RB; LU ZH; LIU TP; JIANG ZW; GALBRAITH WM; AGRAWAL S
      PHARMACOKINETICS AND TISSUE DISTRIBUTION IN RATS OF AN OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE (GEM-91) DEVELOPED AS A THERAPEUTIC AGENT FOR HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1

      Biochemical pharmacology
    40. DIASIO RB; LU ZH
      DIHYDROPYRIMIDINE DEHYDROGENASE-ACTIVITY AND FLUOROURACIL CHEMOTHERAPY

      Journal of clinical oncology
    41. FALANY CN; JOHNSON MR; BARNES S; DIASIO RB
      GLYCINE AND TAURINE CONJUGATION OF BILE-ACIDS BY A SINGLE ENZYME - MOLECULAR-CLONING AND EXPRESSION OF HUMAN LIVER BILE-ACID COA-AMINO ACIDN-ACYLTRANSFERASE

      The Journal of biological chemistry
    42. LU Z; ZHANG R; DIASIO RB
      GENETIC-POLYMORPHISM OF DIHYDROPYRIMIDINE DEHYDROGENASE (DPD), THE KEY ENZYME IN 5-FLUOROURACIL (FURA) CATABOLISM

      Clinical pharmacology and therapeutics
    43. CHENG X; ZHANG R; LU Z; FALANY C; DIASIO RB
      MOLECULAR-CLONING OF DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) - ISOLATION OF CDNA FRAGMENTS OF BOVINE LIVER DPD

      Clinical pharmacology and therapeutics
    44. ZHANG RW; LU ZH; ZHANG XS; DIASIO RB; JIANG ZW; AGRAWAL S
      IN-VIVO BIOSTABILITY, PHARMACOKINETICS, AND DISPOSITION IN RATS OF A SELF-STABILIZED ANTISENSE OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE

      Clinical chemistry
    45. SPARANO JA; WADLER S; DIASIO RB; ZHANG RW; LU ZH; SCHWARTZ EL; EINZIG A; WIERNIK PH
      PHASE-I TRIAL OF LOW-DOSE, PROLONGED CONTINUOUS-INFUSION FLUOROURACILPLUS INTERFERON-ALFA - EVIDENCE FOR ENHANCED FLUOROURACIL TOXICITY WITHOUT PHARMACOKINETIC PERTURBATION

      Journal of clinical oncology
    46. JOHNSON MR; BARNES S; DIASIO RB; FALANY CN
      CLONED HUMAN LIVER BILE-ACID COA - AMINO-ACID N-ACETYLTRANSFERASE (HBAT) USES BOTH GLYCINE AND TAURINE AS SUBSTRATES

      Hepatology
    47. LU ZH; ZHANG RW; DIASIO RB
      DIHYDROPYRIMIDINE DEHYDROGENASE-ACTIVITY IN HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS AND LIVER - POPULATION CHARACTERISTICS, NEWLY IDENTIFIED DEFICIENT PATIENTS, AND CLINICAL IMPLICATION IN 5-FLUOROURACIL CHEMOTHERAPY

      Cancer research
    48. ZHANG RW; LU ZH; LIU TP; SOONG SJ; DIASIO RB
      RELATIONSHIP BETWEEN CIRCADIAN-DEPENDENT TOXICITY OF 5-FLUORODEOXYURIDINE AND CIRCADIAN-RHYTHMS OF PYRIMIDINE ENZYMES - POSSIBLE RELEVANCE TO FLUOROPYRIMIDINE CHEMOTHERAPY

      Cancer research
    49. LU ZH; ZHANG RW; DIASIO RB
      COMPARISON OF DIHYDROPYRIMIDINE DEHYDROGENASE FROM HUMAN, RAT, PIG AND COW LIVER - BIOCHEMICAL AND IMMUNOLOGICAL PROPERTIES

      Biochemical pharmacology
    50. ZHANG RW; LIU TP; SOONG SJ; DIASIO RB
      A MATHEMATICAL-MODEL OF THE KINETICS AND TISSUE DISTRIBUTION OF 2-FLUORO-BETA-ALANINE, THE MAJOR CATABOLITE OF 5-FLUOROURACIL

      Biochemical pharmacology


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/10/20 alle ore 03:12:25