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La ricerca find articoli where authors phrase all words ' Castagnoli, N' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 63 riferimenti
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    1. Kuttab, S; Shang, J; Castagnoli, N
      Rat liver microsomal enzyme catalyzed oxidation of 4-phenyl-trans-1-(2-phenylcyclopropyl)-1,2,3,6-tetrahydropyridine

      BIOORGANIC & MEDICINAL CHEMISTRY
    2. Weidolf, L; Castagnoli, N
      Study of the electrospray ionization mass spectrometry of the proton pump inhibiting drug Omeprazole

      RAPID COMMUNICATIONS IN MASS SPECTROMETRY
    3. Kalgutkar, AS; Dalvie, DK; Castagnoli, N; Taylor, TJ
      Interactions of nitrogen-containing xenobiotics with monoamine oxidase (MAO) isozymes A and B: SAR studies on MAO substrates and inhibitors

      CHEMICAL RESEARCH IN TOXICOLOGY
    4. Castagnoli, KP; Steyn, SJ; Petzer, JP; Van der Schyf, CJ; Castagnoli, N
      Neuroprotection in the MPTP parkinsonian C57BL/6 mouse model by a compoundisolated from tobacco

      CHEMICAL RESEARCH IN TOXICOLOGY
    5. Chen, JF; Xu, K; Petzer, JP; Staal, R; Xu, YH; Beilstein, M; Sonsalla, PK; Castagnoli, K; Castagnoli, N; Schwarzschild, MA
      Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in amodel of Parkinson's disease

      JOURNAL OF NEUROSCIENCE
    6. Isin, EM; de Jonge, M; Castagnoli, N
      Studies on synthetic approaches to 1H- and 2H-indazolyl derivatives

      JOURNAL OF ORGANIC CHEMISTRY
    7. Steyn, SJ; Castagnoli, K; Steyn, S; Castagnoli, N
      Selective inhibition of MAO-B through chronic low-dose (R)-deprenyl treatment in C57BL/6 mice has no effect on basal neostriatal dopamine levels

      EXPERIMENTAL NEUROLOGY
    8. Tanko, JM; Friedline, R; Suleman, NK; Castagnoli, N
      tert-butoxyl as a model for radicals in biological systems: Caveat emptor

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    9. Ooms, F; Delvosal, S; Wouters, J; Durant, F; Dockendolf, G; Van't Land, C; Glass, T; Castagnoli, N; Van der Schyf, CJ
      Empirical and molecular modeling study of the pyridinium species RHPP+, anabundant and potentially neurotoxic metabolite of haloperidol

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
    10. Igarashi, K; Sugiyama, Y; Kasuya, F; Inoue, H; Matoba, R; Castagnoli, N
      Analysis of citrulline in rat brain tissue after perfusion with haloperidol by liquid chromatography-mass spectrometry

      JOURNAL OF CHROMATOGRAPHY B
    11. Liu, X; Castagnoli, K; Van der Schyf, CJ; Castagnoli, N
      Studies on the in vivo biotransformation of the tobacco alkaloid beta-nicotyrine

      CHEMICAL RESEARCH IN TOXICOLOGY
    12. Khalil, AA; Steyn, S; Castagnoli, N
      Isolation and characterization of a monoamine oxidase inhibitor from tobacco leaves

      CHEMICAL RESEARCH IN TOXICOLOGY
    13. Ooms, F; Norberg, B; Isin, EM; Castagnoli, N; Van der Schyf, CJ; Wouters, J
      7-Nitroindazole

      ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
    14. Petzer, JP; Bergh, JJ; Mienie, LJ; Castagnoli, N; Van der Schyf, CJ
      Metabolic defects caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and by HPTP (the tetrahydropyridinyl analog of haloperidol), in rats

      LIFE SCIENCES
    15. Yu, J; Castagnoli, N
      Synthesis and MAO-B substrate properties of 1-methyl-4-heteroaryl-1,2,3,6-tetrahydropyridines

      BIOORGANIC & MEDICINAL CHEMISTRY
    16. Yu, JA; Castagnoli, N
      Synthesis and monoamine oxidase B substrate properties of 1-methyl-4-heteroaryl-1,2,3,6-tetrahydropyridines

      BIOORGANIC & MEDICINAL CHEMISTRY
    17. Liu, X; Zang, LY; Van der Schyf, CJ; Igarashi, K; Castagnoli, K; Castagnoli, N
      Studies on the pyrrolinone metabolites derived from the tobacco alkaloid 1-methyl-2-(3-pyridinyl)pyrrole (beta-nicotyrine)

      CHEMICAL RESEARCH IN TOXICOLOGY
    18. Mienie, LJ; Bergh, JJ; Bloomquist, JR; Castagnoli, N; Steyn, SJ; Van der Schyf, CJ
      p-Fluorophenylglycine in the urine of baboons treated with HPTP, the tetrahydropyridine analog of haloperidol

      LIFE SCIENCES
    19. Inoue, H; Castagnoli, K; Van der Schyf, C; Mabic, S; Igarashi, K; Castagnoli, N
      Species-dependent differences in monoamine oxidase A and B-catalyzed oxidation of various C4 substituted 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridinyl derivatives

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    20. Nimkar, SK; Mabic, S; Anderson, AH; Palmer, SL; Graham, TH; de Jonge, M; Hazelwood, L; Hislop, SJ; Castagnoli, N
      Studies on the monoamine oxidase-B-catalyzed biotransformation of 4-azaaryl-1-methyl-1,2,3,6-tetrahydropyridine derivatives

      JOURNAL OF MEDICINAL CHEMISTRY
    21. Halliday, GM; Pond, SM; Cartwright, H; McRitchie, DA; Castagnoli, N; Van der Schyf, CJ
      Clinical and neuropathological abnormalities in baboons treated with HPTP,the tetrahydropyridine analog of haloperidol

      EXPERIMENTAL NEUROLOGY
    22. Mabic, S; Castagnoli, K; Castagnoli, N
      Oxidative metabolic bioactivation of xenobiotics

      HANDBOOK OF DRUG METABOLISM
    23. FRANOT C; MABIC S; CASTAGNOLI N
      CHEMICAL-MODEL STUDIES ON THE MONOAMINE OXIDASE-B CATALYZED OXIDATIONOF 4-SUBSTITUTED 1-CYCLOPROPYL-1,2,3,6-TETRAHYDROPYRIDINES

      Bioorganic & medicinal chemistry
    24. WANG YX; MABIC S; CASTAGNOLI N
      1-METHYL-3-PYRROLINES AND 2-METHYLISOINDOLINES - NEW CLASSES OF CYCLIC TERTIARY AMINE MONOAMINE-OXIDASE-B SUBSTRATES

      Bioorganic & medicinal chemistry
    25. Zhao, ZY; Mabic, S; Kuttab, S; Franot, C; Castagnoli, K; Castagnoli, N
      Rat liver microsomal enzyme catalyzed oxidation of 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine

      BIOORGANIC & MEDICINAL CHEMISTRY
    26. McRitchie, DA; Cartwright, H; Pond, SM; van der Schyf, CJ; Castagnoli, N; van der Nest, DG; Halliday, GM
      The midbrain dopaminergic cell groups in the baboon Papio ursinus

      BRAIN RESEARCH BULLETIN
    27. Usuki, E; Van der Schyf, CJ; Castagnoli, N
      Metabolism of haloperidol and its tetrahydropyridine dehydration product HPTP

      DRUG METABOLISM REVIEWS
    28. MABIC S; NIMKAR SK; HARRIS DN; HARICH K; CASTAGNOLI N
      ELECTRON IONIZATION-INDUCED LOSS OF A METHYL RADICAL FROM CLOPROPYL-4-SUBSTITUTED-1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES

      Journal of the American Society for Mass Spectrometry
    29. FRANOT C; MABIC S; CASTAGNOLI N
      CHEMICAL-MODEL STUDIES ON THE MONOAMINE OXIDASE-B CATALYZED OXIDATIONOF 4-SUBSTITUTED 1-METHYL-1,2,3,6-TETRAHYDROPYRIDINES

      Bioorganic & medicinal chemistry
    30. WANG YX; CASTAGNOLI N
      POTENTIAL LATENT NITROGEN-MUSTARD DERIVATIVES DESIGNED TO TARGET MONOAMINE-OXIDASE RICH CELLS

      Bioorganic & medicinal chemistry
    31. CASTAGNOLI N; RIMOLDI JM; BLOOMQUIST J; CASTAGNOLI KP
      POTENTIAL METABOLIC BIOACTIVATION PATHWAYS INVOLVING CYCLIC TERTIARY-AMINES AND AZAARENES

      Chemical research in toxicology
    32. CASTAGNOLI K; PALMER S; ANDERSON A; BUETERS T; CASTAGNOLI N
      THE NEURONAL NITRIC-OXIDE SYNTHASE INHIBITOR 7-NITROINDAZOLE ALSO INHIBITS THE MONOAMINE OXIDASE-B-CATALYZED OXIDATION OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE

      Chemical research in toxicology
    33. MABIC S; RIMOLDI JM; CASTAGNOLI N
      REGIOSELECTIVE DEUTERIUM LABELING OF 1,4-DISUBSTITUTED-1,2,3,6-TETRAHYDROPYRIDINES

      Journal of labelled compounds & radiopharmaceuticals
    34. OOMS F; WOUTERS J; DURANT F; CASTAGNOLI N; VANTLAND C; DOCKENDOLF G; GLASS T; VANDERSCHYF CJ
      CONFORMATIONAL DISTRIBUTION OF THE POTENTIALLY NEUROTOXIC METABOLITE OF HALOPERIDOL, HPP-SPECTROSCOPY, X-RAY CRYSTALLOGRAPHY AND MOLECULAR-DYNAMICS SIMULATIONS(, BY NMR)

      Perkin transactions. 2
    35. MIENIE LJ; BERGH JJ; VANSTADEN E; STEYN SJ; POND SM; CASTAGNOLI N; VANDERSCHYF CJ
      METABOLIC DEFECTS CAUSED BY TREATMENT WITH THE TETRAHYDROPYRIDINE ANALOG OF HALOPERIDOL (HPTP), IN BABOONS

      Life sciences
    36. DIMONTE DA; ROYLAND JE; ANDERSON A; CASTAGNOLI K; CASTAGNOLI N; LANGSTON JW
      INHIBITION OF MONOAMINE-OXIDASE CONTRIBUTES TO THE PROTECTIVE EFFECT OF 7-NITROINDAZOLE AGAINST MPTP NEUROTOXICITY

      Journal of neurochemistry
    37. PALMER SL; MABIC S; CASTAGNOLI N
      PROBING THE ACTIVE-SITES OF MONOAMINE-OXIDASE-A AND MONOAMINE-OXIDASE-B WITH 1,4-DISUBSTITUTED TETRAHYDROPYRIDINE SUBSTRATES AND INACTIVATORS

      Journal of medicinal chemistry
    38. FASCIANO J; STEELE T; CASTAGNOLI N; KATZ J; RICAURTE G
      THE EFFECT OF N-METHYLATION ON FENFLURAMINES NEUROTOXIC AND PHARMACOLOGICAL ACTIONS

      Brain research
    39. OLIVER DW; DORMEHL IC; VANDERSCHYF CJ; NEUMEYER JL; HUGO N; KEEVE R; ROSSOUW NT; MULLERGARTNER HW; CASTAGNOLI N
      EFFECT OF THE HALOPERIDOL TETRAHYDROPYRIDINE METABOLITE UOROPHENYL)-4-OXOBUTYL]-1,2,3,6-TETRAHYDROPYRIDINE ON DOPAMINE-RECEPTOR AND TRANSPORTER BINDING - A NONHUMAN PRIMATE I-123 IODOBENZAMIDE AND 2-BETA-CARBOMETHOXY-3-BETA-(4-IODOPHENYL)TROPANE SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHIC STUDY

      Arzneimittel-Forschung
    40. NIMKAR SK; ANDERSON AH; RIMOLDI JM; STANTON M; CASTAGNOLI KP; MABIC S; WANG YX; CASTAGNOLI N
      SYNTHESIS AND MONOAMINE-OXIDASE-B CATALYZED OXIDATION OF C-4 HETEROAROMATIC SUBSTITUTED 1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES

      Chemical research in toxicology
    41. MABIC S; CASTAGNOLI N
      REGIOSELECTIVE SYNTHESIS OF DEUTERATED ANALOGS OF THE NEUROTOXIN MPTP

      Journal of labelled compounds & radiopharmaceuticals
    42. IGARASHI K; MATSUBARA K; KASUYA F; FUKUI M; IDZU T; CASTAGNOLI N
      EFFECT OF A PYRIDINIUM METABOLITE DERIVED FROM HALOPERIDOL ON THE ACTIVITIES OF STRIATAL TYROSINE-HYDROXYLASE IN FREELY MOVING RATS

      Neuroscience letters
    43. VANDERSCHYF CJ; DORMEHL IC; OLIVER DW; HUGO N; KEEVE R; MULLERGARTNER HW; POND SM; CASTAGNOLI N
      LONG-TERM TREATMENT WITH THE TETRAHYDROPYRIDINE ANALOG (HPTP) OF HALOPERIDOL INFLUENCES DOPAMINE LIGAND-BINDING IN BABOON BRAIN - AN [I-123] IODOBENZAMIDE (IBZM) SPECT STUDY

      Molecular brain research
    44. WOUTERS J; EVRARD G; DURANT F; KALGUTKAR A; CASTAGNOLI N
      AN MPP(- THE 2() ANALOG )1 N-CYCLOPENTYL-4-PHENYLPYRIDINIUM BROMIDE-4-PHENYLPYRIDINE COMPLEX/

      Acta crystallographica. Section C, Crystal structure communications
    45. SONG XO; EHRICH M; FLAHERTY D; WANG YX; CASTAGNOLI N
      BIOTRANSFORMATION OF THE MPTP ANALOG THYLAMINOPHENYLETHENYL]-1,2,3,6-TETRAHYDROPYRIDINE TO A FLUORESCENT PYRIDINIUM METABOLITE BY INTACT NEUROBLASTOMA-CELLS

      Toxicology and applied pharmacology
    46. AVENT KM; USUKI E; EYLES DW; KEEVE R; VANDERSCHYF CJ; CASTAGNOLI N; POND SM
      HALOPERIDOL AND ITS TETRAHYDROPYRIDINE DERIVATIVE (HPTP) ARE METABOLIZED TO POTENTIALLY NEUROTOXIC PYRIDINIUM SPECIES IN THE BABOON

      Life sciences
    47. BRAND L; OLIVER DW; VANDERSCHYF CJ; POND SM; CASTAGNOLI N
      DOPAMINE-RECEPTOR BINDING OF UOROPHENYL)-4-OXOBUTYL]-1,2,3,6-TETRAHYDROPYRIDINE (HPTP), AN INTERMEDIATE METABOLITE OF HALOPERIDOL

      Life sciences
    48. MABIC S; CASTAGNOLI N
      SELECTIVE REDUCTIONS OF 1-METHYL-4-PHENYL-2-PYRIDONE

      Journal of organic chemistry
    49. FLAHERTY P; CASTAGNOLI K; WANG YX; CASTAGNOLI N
      SYNTHESIS AND SELECTIVE MONOAMINE-OXIDASE B-INHIBITING PROPERTIES OF 1-METHYL-1,2,3,6-TETRAHYDROPYRID-4-YL CARBAMATE DERIVATIVES - POTENTIAL PRODRUGS OF (R)-NORDEPRENYL AND (S)-NORDEPRENYL

      Journal of medicinal chemistry
    50. MABIC S; CASTAGNOLI N
      ASSESSMENT OF STRUCTURAL REQUIREMENTS FOR THE MONOAMINE OXIDASE-B-CATALYZED OXIDATION OF 1,4-DISUBSTITUTED-1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES RELATED THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE

      Journal of medicinal chemistry
    51. ANDERSON AH; KUTTAB S; CASTAGNOLI N
      DEUTERIUM-ISOTOPE EFFECT STUDIES ON THE MAO-B CATALYZED OXIDATION OF 4-BENZYL-1-CYCLOPROPYL-1,2,3,6-TETRAHYDROPYRIDINE

      Biochemistry
    52. RIMOLDI JM; WANG YX; NIMKAR SK; KUTTAB SH; ANDERSON AH; BURCH H; CASTAGNOLI N
      PROBING THE MECHANISM OF BIOACTIVATION OF MPTP TYPE ANALOGS BY MONOAMINE-OXIDASE B - STRUCTURE-ACTIVITY STUDIES ON SUBSTITUTED PHENOXY-1-CYCLOPROPYL-1,2,3,6-TETRAHYDROPYRIDINES, -PHENYL-1-CYCLOPROPYL-1,2,3,6-TETRAHYDROPYRIDINES, AND OPHENOXY-1-CYCLOPROPYL-1,2,3,6-TETRAHYDROPYRIDINES

      Chemical research in toxicology
    53. KALGUTKAR AS; CASTAGNOLI N; TESTA B
      SELECTIVE INHIBITORS OF MONOAMINE-OXIDASE (MAO-A AND MAO-B) AS PROBESOF ITS CATALYTIC SITE AND MECHANISM

      Medicinal research reviews
    54. SMALLWOOD RA; BERLIN RG; CASTAGNOLI N; FESTEN HPM; HAWKEY CJ; LAM SK; LANGMAN MJS; LUNDBORG P; PARKINSON A
      SAFETY OF ACID-SUPPRESSING DRUGS

      Digestive diseases and sciences
    55. CARLSON TJ; JONES JP; PETERSON L; CASTAGNOLI N; IYER KR; TRAGER WF
      STEREOSELECTIVITY AND ISOTOPE EFFECTS ASSOCIATED WITH CYTOCHROME P450-CATALYZED OXIDATION OF (S)-NICOTINE - THE POSSIBILITY OF INITIAL HYDROGEN ATOM ABSTRACTION IN THE FORMATION OF THE DELTA-1',5'-NICOTINIUM ION

      Drug metabolism and disposition
    56. WANG YX; CASTAGNOLI N
      DECYCLOPROPYLATION OF CYCLOPROPYL-4-HYDROXY-4-(2-METHYLPHENYL)PIPERIDINE N-OXIDE

      Tetrahedron letters
    57. IGARASHI K; KASUYA F; FUKUI M; USUKI E; CASTAGNOLI N
      STUDIES ON THE METABOLISM OF HALOPERIDOL (HP) - THE ROLE OF CYP3A IN THE PRODUCTION OF THE NEUROTOXIC PYRIDINIUM METABOLITE HPP-BRAIN FOLLOWING IP ADMINISTRATION OF HP( FOUND IN RAT)

      Life sciences
    58. WANG YX; CASTAGNOLI N
      STUDIES ON THE MONOAMINE-OXIDASE (MAO)-CATALYZED OXIDATION OF PHENYL-SUBSTITUTED 1-METHYL-4-PHENOXY-1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES - FACTORS CONTRIBUTING TO MAO-A AND MAO-B SELECTIVITY

      Journal of medicinal chemistry
    59. KUTTAB S; KALGUTKAR A; CASTAGNOLI N
      MECHANISTIC STUDIES ON THE MONOAMINE-OXIDASE-B CATALYZED OXIDATION OF1,4-DISUBSTITUTED TETRAHYDROPYRIDINES

      Chemical research in toxicology
    60. VANDERSCHYF CJ; CASTAGNOLI K; USUKI E; FOUDA HG; RIMOLDI JM; CASTAGNOLI N
      METABOLIC STUDIES ON HALOPERIDOL AND ITS TETRAHYDROPYRIDINE ANALOG INC57BL 6 MICE/

      Chemical research in toxicology
    61. BLOOMQUIST J; KING E; WRIGHT A; MYTILINEOU C; KIMURA K; CASTAGNOLI K; CASTAGNOLI N
      1-METHYL-4-PHENYLPYRIDINIUM-LIKE NEUROTOXICITY OF A PYRIDINIUM METABOLITE DERIVED FROM HALOPERIDOL - CELL-CULTURE AND NEUROTRANSMITTER UPTAKE STUDIES

      The Journal of pharmacology and experimental therapeutics
    62. ROLLEMA H; SKOLNIK M; DENGELBRONNER J; IGARASHI K; USUKI E; CASTAGNOLI N
      MPP(-LIKE NEUROTOXICITY OF A PYRIDINIUM METABOLITE DERIVED FROM HALOPERIDOL - IN-VIVO MICRODIALYSIS AND IN-VITRO MITOCHONDRIAL STUDIES())

      The Journal of pharmacology and experimental therapeutics
    63. KALGUTKAR AS; CASTAGNOLI K; HALL A; CASTAGNOLI N
      NOVEL 4-(ARYLOXY)TETRAHYDROPYRIDINE ANALOGS OF MPTP AS MONOAMINE-OXIDASE-A AND MONOAMINE-OXIDASE-B SUBSTRATES

      Journal of medicinal chemistry


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Documento generato il 15/08/20 alle ore 02:04:29