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    1. Huitema, ADR; Mathot, RAA; Tibben, MM; Rodenhuis, S; Beijnen, JH
      A mechanism-based pharmacokinetic model for the cytochrome P450 drug-drug interaction between cyclophosphamide and thioTEPA and the autoinduction of cyclophosphamide

      JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
    2. Veldkamp, AI; van Heeswijk, RPG; Mulder, JW; Meenhorst, PL; Schreij, G; van der Geest, S; Lange, JMA; Beijnen, JH; Hoetelmans, RMW
      Steady-state pharmacokinetics of twice-daily dosing of saquinavir plus ritonavir in HIV-1-infected individuals

      JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
    3. Schoemaker, NE; Frigerio, E; Fraier, D; Schellens, JHM; Rosing, H; Jansen, S; Beijnen, JH
      High-performance liquid chromatographic analysis for the determination of a novel polymer-bound camptothecin derivative (MAG-camptothecin) and free camptothecin in human plasma

      JOURNAL OF CHROMATOGRAPHY B
    4. Bardelmeijer, HA; Ouwehand, M; Beijnen, JH; Schellens, JHM; van Tellingen, O
      Determination of cyclosporin A in human and mouse plasma by reversed-phasehigh-performance liquid chromatography

      JOURNAL OF CHROMATOGRAPHY B
    5. Kemper, EM; Jansen, B; Brouwer, KR; Schellens, JHM; Beijnen, JH; van Tellingen, O
      Bioanalysis and preliminary pharmacokinetics of the acridonecarboxamide derivative GF120918 in plasma of mice and humans by ion-pairing reversed-phase high-performance liquid chromatography with fluorescence detection

      JOURNAL OF CHROMATOGRAPHY B
    6. Huitema, ADR; Reinders, C; Tibben, MM; Rodenhuis, S; Beijnen, JH
      Sensitive gas chromatographic determination of the cyclophosphamide metabolite 2-dechloroethylcyclophosphamide in human plasma

      JOURNAL OF CHROMATOGRAPHY B
    7. Waterval, JCM; Bloks, JC; Sparidans, RW; Beijnen, JH; Rodriguez-Campos, IM; Bult, A; Lingeman, H; Underberg, WJM
      Degradation kinetics of aplidine, a new marine antitumoural cyclic peptide, in aqueous solution

      JOURNAL OF CHROMATOGRAPHY B
    8. Sparidans, RW; Hoetelmans, RMW; Beijnen, JH
      Liquid chromatographic assay for simultaneous determination of abacavir and mycophenolic acid in human plasma using dual spectrophotometric detection

      JOURNAL OF CHROMATOGRAPHY B
    9. Malingre, MM; Rosing, H; Koopman, FJ; Schellens, JHM; Beijnen, JH
      Performance of the analytical assays of paclitaxel, docetaxel, and cyclosporin a in a routine hospital laboratory setting

      JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
    10. Maliepaard, M; van Gastelen, MA; Tohgo, A; Hausheer, FH; van Waardenburg, RCAM; de Jong, LA; Pluim, D; Beijnen, JH; Schellens, JHM
      Circumvention of breast cancer resistance protein (BCRP)-mediated resistance to camptothecins in vitro using non-substrate drugs or the BCRP inhibitor GF120918

      CLINICAL CANCER RESEARCH
    11. Witkamp, AJ; de Bree, E; Kaag, MM; Boot, H; Beijnen, JH; van Slooten, GW; van Coevorden, F; Zoetmulder, FAN
      Extensive cytoreductive surgery followed by intra-operative hyperthermic intraperitoneal chemotherapy with mitomycin-C in patients with peritoneal carcinomatosis of colorectal origin

      EUROPEAN JOURNAL OF CANCER
    12. Sparidans, RW; Rosing, H; Hillebrand, MJX; Lopez-Lazaro, L; Jimeno, JM; Manzanares, I; van Kesteren, C; Cvitkovic, E; van Oosterom, AT; Schellens, JHM; Beijnen, JH
      Search for metabolites of ecteinascidin 743, a novel, marine-derived, anti-cancer agent, in man

      ANTI-CANCER DRUGS
    13. Sparidans, RW; Stokvis, E; Jimeno, JM; Lopez-Lazaro, L; Schellens, JHM; Beijnen, JH
      Chemical and enzymatic stability of a cyclic depsipeptide, the novel, marine-derived, anti-cancer agent kahalalide F

      ANTI-CANCER DRUGS
    14. Malingre, MM; Huinink, WWT; Duchin, K; Schellens, JHM; Beijnen, JH
      Pharmacokinetics of oral cyclosporin A when co-administered to enhance theoral absorption of paclitaxel

      ANTI-CANCER DRUGS
    15. van Maanen, MJ; Huitema, ADR; Rodenhuis, S; Beijnen, JH
      Urinary excretion of thioTEPA and its metabolites in patients treated withhigh-dose cyclophosphamide, thioTEPA and carboplatin

      ANTI-CANCER DRUGS
    16. Terwogt, JMM; Huinink, WWT; Schellens, JHM; Schot, M; Mandjes, IAM; Zurlo, MG; Rocchetti, M; Rosing, H; Koopman, FJ; Beijnen, JH
      Phase I clinical and pharmacokinetic study of PNU166945, a novel water-soluble polymer-conjugated prodrug of paclitaxel

      ANTI-CANCER DRUGS
    17. Malingre, MM; Beijnen, JH; Rosing, H; Koopman, FJ; van Tellingen, O; Duchin, K; Huinink, WWT; Swart, M; Lieverst, J; Schellens, JHM
      The effect of different doses of cyclosporin A on the systemic exposure oforally administered paclitaxel

      ANTI-CANCER DRUGS
    18. Crul, M; de Klerk, GJ; Beijnen, JH; Schellens, JHM
      Ras biochemistry and farnesyl transferase inhibitors: a literature survey

      ANTI-CANCER DRUGS
    19. Crul, M; van den Bongard, HJGD; Tibben, MM; van Tellingen, O; Sava, G; Schellens, JHM; Beijnen, JH
      Validated method for the determination of the novel organo-ruthenium anticancer drug NAMI-A in human biological fluids by Zeeman atomic absorption spectrometry

      FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY
    20. van Putten, JWG; Kerbush, T; Smit, EF; van Rijswijk, R; Beijnen, JH; Sleijfer, DT; Groen, HJM
      Dose-finding and pharmacological study of ifosfamide in combination with paclitaxel and carboplatin in resistant small-cell lung cancer

      ANNALS OF ONCOLOGY
    21. Malingre, MM; Richel, DJ; Beijnen, JH; Rosing, H; Koopman, FJ; Huinink, WWTB; Schot, ME; Schellens, JHM
      Coadministration of cyclosporine strongly enhances the oral bioavailability of docetaxel

      JOURNAL OF CLINICAL ONCOLOGY
    22. Nuijen, B; Bouma, M; Talsma, H; Manada, C; Jimeno, JM; Lopez-Lazaro, L; Bult, A; Beijnen, JH
      Development of a lyophilized parenteral pharmaceutical formulation of the investigational polypeptide marine anticancer agent kahalalide F

      DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
    23. Kerbusch, T; vanPutten, JWG; Groen, HJM; Huitema, ADR; Mathot, RAA; Beijnen, JH
      Population pharmacokinetics of ifosfamide and its 2-and 3-dechloroethylated and 4-hydroxylated metabolites in resistant small-cell lung cancer patients

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    24. van den Bongard, HJGD; Mathot, RAA; Boogerd, W; Schornagel, JH; Soesan, M; Schellens, JHM; Beijnen, JH
      Successful rescue with leucovorin and thymidine in a patient with high-dose methotrexate induced acute renal failure

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    25. Malingre, MM; Beijnen, JH; Rosing, H; Koopman, FJ; van Tellingen, O; Duchin, K; Huinink, WWT; Swart, M; Lieverst, J; Schellens, JHM
      A phase I and pharmacokinetic study of bi-daily dosing of oral paclitaxel in combination with cyclosporin A

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    26. Kerbusch, T; de Kraker, J; Mathot, RAA; Beijnen, JH
      Population pharmacokinetics of ifosfamide and its dechloroethylated and hydroxylated metabolites in children with malignant disease - A sparse sampling approach

      CLINICAL PHARMACOKINETICS
    27. Kerbusch, T; de Kraker, J; Keizer, HJ; van Putten, JWG; Groen, HJM; Jansen, RLH; Schellens, JHM; Beijnen, JH
      Clinical pharmacokinetics and pharmacodynamics of ifosfamide and its metabolites

      CLINICAL PHARMACOKINETICS
    28. Koks, CHW; Crommentuyn, KML; Hoetelmans, RMW; Burger, DM; Koopmans, PP; Mathot, RAA; Mulder, JW; Meenhorst, PL; Beijnen, JH
      The effect of fluconazole on ritonavir and saquinavir pharmacokinetics in HIV-1-infected individuals

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    29. Huitema, ADR; Mathot, RAA; Tibben, MM; Schellens, JHM; Rodenhuis, S; Beijnen, JH
      Population pharmacokinetics of thioTEPA and its active metabolite TEPA in patients undergoing high-dose chemotherapy

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    30. Van den Brande, J; Panday, VRN; Hoekman, K; Rosing, H; Huijskes, RVHP; Verheijen, RHM; Beijnen, JH; Vermorken, JB
      Pharmacologic study of paclitaxel administered with or without the cytoprotective agent amifostine, and given as a single agent or in combination with epirubicin and cisplatin in patients with advanced solid tumors

      AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
    31. Veldkamp, AI; Weverling, GJ; Lange, JMA; Montaner, JSG; Reiss, P; Cooper, DA; Vella, S; Hall, D; Beijnen, JH; Hoetelmans, RMW
      High exposure to nevirapine in plasma is associated with an improved virological response in HIV-1-infected individuals

      AIDS
    32. de Maat, MMR; Hoetelmans, RMW; Mathot, RAA; van Gorp, ECM; Meenhorst, PL; Mulder, JW; Beijnen, JH
      Drug interaction between St John's wort and nevirapine

      AIDS
    33. Schrama, JG; Baars, JW; Holtkamp, MJ; Schornagel, JH; Beijnen, JH; Rodenhuis, S
      Phase II study of a multi-course high-dose chemotherapy regimen incorporating cyclophosphamide, thiotepa, and carboplatin in stage IV breast cancer

      BONE MARROW TRANSPLANTATION
    34. Nuijen, B; Bouma, M; Manada, C; Jimeno, JM; Lazaro, LL; Bult, A; Beijnen, JH
      Compatibility and stability of the investigational polypeptide marine anticancer agent kahalalide F in infusion devices

      INVESTIGATIONAL NEW DRUGS
    35. Nuijen, B; Bouma, M; Schellens, JHM; Beijnen, JH
      Progress in the development of alternative pharmaceutical formulations of taxanes

      INVESTIGATIONAL NEW DRUGS
    36. Malingre, MM; Beijnen, JH; Schellens, JHM
      Oral delivery of taxanes

      INVESTIGATIONAL NEW DRUGS
    37. Albrecht, KW; Hamer, PCD; Leenstra, S; Bakker, PJM; Beijnen, JH; Troost, D; Kaaijk, P; Bosch, AD
      High concentration of daunorubicin and daunorubicinol in human malignant astrocytomas after systemic administration of liposomal daunorubicin

      JOURNAL OF NEURO-ONCOLOGY
    38. Veldkamp, AI; van Heeswijk, RPG; Mulder, JW; Meenhorst, PL; Hoetelmans, RMW; Lange, JMA; Beijnen, JH
      Limited sampling strategies for the estimation of the systemic exposure tothe HIV-1 nonnucleoside reverse transcriptase inhibitor nevirapine

      THERAPEUTIC DRUG MONITORING
    39. Huitema, ADR; Mathot, RAA; Tibben, MM; Rodenhuis, S; Beijnen, JH
      Validation of a therapeutic drug monitoring strategy for thiotepa in a high-dose chemotherapy regimen

      THERAPEUTIC DRUG MONITORING
    40. Koks, CHW; Crommentuyn, KML; Hoetelmans, RMW; Mathot, RAA; Beijnen, JH
      Can fluconazole concentrations in saliva be used for therapeutic drug monitoring?

      THERAPEUTIC DRUG MONITORING
    41. van Heeswijk, RPG; Veldkamp, AI; Mulder, JW; Meenhorst, PL; Beijnen, JH; Lange, JMA; Hoetelmans, RMW
      Saliva as an alternative body fluid for therapeutic drug monitoring of thenonnucleoside reverse transcription inhibitor nevirapine

      THERAPEUTIC DRUG MONITORING
    42. Kerbusch, T; Herben, VMM; Jeuken, MJJ; Ouwerkerk, J; Keizer, HJ; Beijnen, JH
      Distribution of ifosfamide and metabolites between plasma and erythrocytes

      BIOPHARMACEUTICS & DRUG DISPOSITION
    43. Kerbusch, T; Mathot, RAA; Keizer, HJ; Kaijser, GP; Schellens, JHM; Beijnen, JH
      Influence of dose and infusion duration on pharmacokinetics of ifosfamide and metabolites

      DRUG METABOLISM AND DISPOSITION
    44. Kerbusch, T; Mathot, RAA; Keizer, HJ; Ouwerkerk, J; Rodenhuis, S; Schellens, JHM; Beijnen, JH
      Population pharmacokinetics and exploratory pharmacodynamics of ifosfamideand metabolites after a 72-h continuous infusion in patients with soft tissue sarcoma

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    45. Malingre, MM; Huinink, WWT; Mackay, M; Schellens, JHM; Beijnen, JH
      Pharmacokinetics of oral cyclosporin A when co-administered to enhance theabsorption of orally administered docetaxel

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    46. Huisman, MT; Smit, JW; Wiltshire, HR; Hoetelmans, RMW; Beijnen, JH; Schinkel, AH
      P-glycoprotein limits oral availability, brain, and fetal penetration of saquinavir even with high doses of ritonavir

      MOLECULAR PHARMACOLOGY
    47. Veldkamp, AI; Harris, M; Montaner, JSG; Moyle, G; Gazzard, B; Youle, M; Johnson, M; Kwakkelstein, MO; Carlier, H; van Leeuwen, R; Beijnen, JH; Lange, JMA; Reiss, P; Hoetelmans, RMW
      The steady-state pharmacokinetics of efavirenz and nevirapine when used incombination in human immunodeficiency virus type 1-infected persons

      JOURNAL OF INFECTIOUS DISEASES
    48. Zelcer, N; Saeki, T; Reid, G; Beijnen, JH; Borst, P
      Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3)

      JOURNAL OF BIOLOGICAL CHEMISTRY
    49. Kerbusch, T; Jansen, RLH; Mathot, RAA; Huitema, ADR; Jansen, M; van Rijswijk, REN; Beijnen, JH
      Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    50. Malingre, MM; Beijnen, JH; Rosing, H; Koopman, FJ; Jewell, RC; Paul, EM; Huinink, WWT; Schellens, JHM
      Co-administration of GF120918 significantly increases the systemic exposure to oral paclitaxel in cancer patients

      BRITISH JOURNAL OF CANCER
    51. Rodenhuis, S; Huitema, ADR; van Dam, FSAM; de Vries, EGE; Beijnen, JH
      High-dose chemotherapy with peripheral blood progenitor cell transplantation in the adjuvant treatment of breast cancer

      CANCER JOURNAL
    52. van Heeswijk, RPG; Veldkamp, AI; Mulder, JW; Meenhorst, PL; Wit, FWNM; Reiss, P; Lange, JMA; Kwakkelstein, MO; Beijnen, JH; Hoetelmans, RMW
      Nevirapine plus didanosine: Once or twice daily combination?

      JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
    53. Huitema, ADR; Tibben, MM; Kerbusch, T; Kettenes-van den Bosch, JJ; Rodenhuis, S; Beijnen, JH
      Simple and selective determination of the cyclophosphamide metabolite phosphoramide mustard in human plasma using high-performance liquid chromatography

      JOURNAL OF CHROMATOGRAPHY B
    54. van Maanen, MJ; Smits, KD; Beijnen, JH
      Simultaneous determination of thioTEPA, TEPA and a novel, recently identified thioTEPA metabolite, monochloroTEPA, in urine using capillary gas chromatography

      JOURNAL OF CHROMATOGRAPHY B
    55. Sparidans, RW; Hoetelmans, RMW; Beijnen, JH
      Sensitive liquid chromatographic assay for amprenavir, a human immunodeficiency virus protease inhibitor, in human plasma, cerebrospinal fluid and semen

      JOURNAL OF CHROMATOGRAPHY B
    56. Sparidans, RW; den Hartigh, J; Cremers, S; Beijnen, JH; Vermeij, P
      Semi-automatic liquid chromatographic analysis of olpadronate in urine andserum using derivatization with (9-fluorenylmethyl)chloroformate

      JOURNAL OF CHROMATOGRAPHY B
    57. Terwogt, JMM; Rosing, H; Rocchetti, M; Frigerio, E; Fraier, D; Koopman, FJ; Schellens, JHM; Huinink, WWT; Beijnen, JH
      High-performance liquid chromatographic methods for the determination of anovel polymer-bound paclitaxel derivative and free paclitaxel in human plasma

      JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
    58. Rosing, H; Man, WY; Doyle, E; Bult, A; Beijnen, JH
      Bioanalytical liquid chromatographic method validation. A review of current practices and procedures

      JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
    59. Kerbusch, T; Huitema, ADR; Jeuken, MJJ; Derraz, J; Tibben, MM; Beijnen, JH
      Simultaneous determination of ifosfamide and its metabolite ifosforamide mustard in human plasma by high performance liquid chromatography

      JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
    60. Huitema, ADR; Tibben, MM; Kerbusch, T; Kettenes-van den Bosch, JJ; Rodenhuis, S; Beijnen, JH
      High performance liquid chromatographic determination of the stabilized cyclophosphamide metabolite 4-hydroxycyclophosphamide in plasma and red bloodcells

      JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
    61. van Kesteren, C; Cvitkovic, E; Taamma, A; Lopez-Lazaro, L; Jimeno, JM; Guzman, C; Mathot, RAA; Schellens, JHM; Misset, JL; Brain, E; Hillebrand, MJX; Rosing, H; Beijnen, JH
      Pharmacokinetics and pharmacodynamics of the novel marine-derived anticancer agent ecteinascidin 743 in a phase I dose-finding study

      CLINICAL CANCER RESEARCH
    62. Bardelmeijer, HA; Beijnen, JH; Brouwer, KR; Rosing, H; Nooijen, WJ; Schellens, JHM; van Tellingen, O
      Increased oral bioavailability of paclitaxel by GF120918 in mice through selective modulation of P-glycoprotein

      CLINICAL CANCER RESEARCH
    63. Kuiper, RAJ; Malingre, MM; Beijnen, JH; Schellens, JHM
      Cyclosporine-induced anaphylaxis

      ANNALS OF PHARMACOTHERAPY
    64. Terwogt, JMM; van Tellingen, O; Panday, VRN; Huizing, MT; Schellens, JHM; Huinink, WWT; Boschma, MUS; Giaccone, G; Veenhof, CHN; Beijnen, JH
      Cremophor EL pharmacokinetics in a phase I study of paclitaxel (Taxol (R))and carboplatin in non-small cell lung cancer patients

      ANTI-CANCER DRUGS
    65. Huitema, ADR; Smits, KD; Mathot, RAA; Schellans, JHM; Rodenhuis, S; Beijnen, JH
      The clinical pharmacology of alkylating agents in high-dose chemotherapy

      ANTI-CANCER DRUGS
    66. Kruijtzer, CMF; Verweij, J; Schellens, JHM; Beijnen, JH; Pronk, L; Bo, M; Lustig, V; van Tinteren, H; Mackay, M; Huinink, WWT
      Docetaxel in 253 previously treated patients with progressive locally advanced or metastatic breast cancer: Results of a compassionate use program inThe Netherlands

      ANTI-CANCER DRUGS
    67. Nuijen, B; Bouma, M; Manada, C; Jimeno, JM; Schellens, JHM; Bult, A; Beijnen, JH
      Pharmaceutical development of anticancer agents derived from marine sources

      ANTI-CANCER DRUGS
    68. Malingre, MM; Schellens, JHM; van Tellingen, O; Rosing, H; Koopman, FJ; Duchin, K; Huinink, WWT; Swart, M; Beijnen, JH
      Metabolism and excretion of paclitaxel after oral administration in combination with cyclosporin A and after i.v. administration

      ANTI-CANCER DRUGS
    69. Terwogt, JMM; Tibben, MM; Welbank, H; Schellens, JHM; Beijnen, JH
      Validated method for the determination of platinum from a liposomal source(SPI-77) in human plasma using graphite furnace Zeeman atomic absorption spectrometry

      FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY
    70. Schellens, JHM; Malingre, MM; Kruijtzer, CMF; Bardelmeijer, HA; van Tellingen, O; Schinkel, AH; Beijnen, JH
      Modulation of oral bioavailability of anticancer drugs: from mouse to man

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    71. van der Vange, N; van Goethem, AR; Zoetmulder, FAN; Kaag, MM; van de Vaart, PJM; Huinink, WWT; Beijnen, JH
      Extensive cytoreductive surgery combined with intra-operative intraperitoneal perfusion with cisplatin under hyperthermic conditions (OVHIPEC) in patients with recurrent ovarian cancer: a feasibility pilot

      EUROPEAN JOURNAL OF SURGICAL ONCOLOGY
    72. Malingre, MM; Terwogt, JMM; Beijnen, JH; Rosing, H; Koopman, FJ; van Tellingen, O; Duchin, K; Huinink, WWT; Swart, M; Lieverst, J; Schellens, JHM
      Phase I and pharmacokinetic study of oral paclitaxel

      JOURNAL OF CLINICAL ONCOLOGY
    73. van Maanen, MJ; Smits, KD; Damen, JMA; Heck, AJR; Beijnen, JH
      Stability of thioTEPA and its metabolites, TEPA, monochloroTEPA and thioTEPA-mercapturate, in plasma and urine

      INTERNATIONAL JOURNAL OF PHARMACEUTICS
    74. van Maanen, RJ; Tijhof, IM; Damen, JMA; Zwikker, JW; Beijnen, JH
      The degradation of N,N ',N ''-triethylenephosphoramide in aqueous solutions: a qualitative and kinetic study

      INTERNATIONAL JOURNAL OF PHARMACEUTICS
    75. Nuijen, B; Bouma, M; Henrar, REC; Brauns, U; Bette, P; Bult, A; Beijnen, JH
      In vitro biocompatibility studies with the experimental anticancer agent BIBX1382BS

      INTERNATIONAL JOURNAL OF PHARMACEUTICS
    76. Huitema, ADR; Kerbusch, T; Tibben, MM; Rodenhuis, S; Beijnen, JH
      Reduction of cyclophosphamide bioactivation by thioTEPA: critical sequence-dependency in high-dose chemotherapy regimens

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    77. Westermann, AR; Dubbelman, R; Baars, JP; Moolenaar, WH; Beijnen, JH; Rodenhuis, S
      Feasibility and pharmacokinetics of intraperitoneal suramin in advanced malignancy

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    78. Kruijtzer, CMF; Beijnen, JH; Swart, M; Schellens, JHM
      Successful treatment with paclitaxel of a patient with metastatic extra-adrenal pheochromocytoma (paraganglioma) - A case report and review of the literature

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    79. Rosing, H; Lustig, V; van Warmerdam, LJC; Huizing, MT; Huinink, WWT; Schellens, JHM; Rodenhuis, S; Bult, A; Beijnen, JH
      Pharmacokinetics and metabolism of docetaxel administered as a 1-h intravenous infusion

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    80. van den Bongard, HJGD; Mathot, RAA; Beijnen, JH; Schellens, JHM
      Pharmacokinetically guided administration of chemotherapeutic agents

      CLINICAL PHARMACOKINETICS
    81. Kerbusch, T; Huitema, ADR; Ouwerkerk, J; Keizer, HJ; Mathot, RAA; Schellens, JHM; Beijnen, JH
      Evaluation of the autoinduction of ifosfamide metabolism by a population pharmacokinetic approach using NONMEM

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    82. van Maanen, MJ; Smeets, CJM; Beijnen, JH
      Chemistry, pharmacology and pharmacokinetics of N,N ',N ''-triethylenethiophosphoramide (ThioTEPA)

      CANCER TREATMENT REVIEWS
    83. van Heeswijk, RPG; Veldkamp, AI; Mulder, JW; Meenhorst, PL; Lange, JMA; Beijnen, JH; Hoetelmans, RMW
      Once-daily dosing of saquinavir and low-dose ritonavir in HIV-1-infected individuals: a pharmacokinetic pilot study

      AIDS
    84. van Heeswijk, RPG; Veldkamp, AI; Mulder, JW; Meenhorst, PL; Wit, FWNM; Lange, JMA; Danner, SA; Foudraine, NA; Kwakkelstein, MO; Reiss, P; Beijnen, JH; Hoetelmans, RMW
      The steady-state pharmacokinetics of nevirapine during once daily and twice daily dosing in HIV-1-infected individuals

      AIDS
    85. Koks, CHW; van Heeswijk, RPG; Veldkamp, AI; Meenhorst, PL; Mulder, JW; van der Meer, JTM; Beijnen, JH; Hoetelmans, RMW
      Itraconazole as an alternative for ritonavir liquid formulation when combined with saquinavir

      AIDS
    86. Bardelmeijer, HA; van Tellingen, O; Schellens, JHM; Beijnen, JH
      The oral route for the administration of cytotoxic drugs: strategies to increase the efficiency and consistency of drug delivery

      INVESTIGATIONAL NEW DRUGS
    87. Kerbusch, T; Jeuken, MJ; Derraz, J; van Putten, JWG; Huitema, ADR; Beijnen, JH
      Determination of ifosfamide, 2-and 3-dechloroethyifosfamide using gas chromatography with nitrogen-phosphorus or mass spectrometry detection

      THERAPEUTIC DRUG MONITORING
    88. van Asperen, J; van Tellingen, O; Beijnen, JH
      The role of MDR1A P-glycoprotein in the biliary and intestinal secretion of doxorubicin and vinblastine in mice

      DRUG METABOLISM AND DISPOSITION
    89. Wijnholds, J; Mol, CAAM; van Deemter, L; de Haas, M; Scheffer, GL; Baas, F; Beijnen, JH; Scheper, RJ; Hatse, S; De Clercq, E; Balzarini, J; Borst, P
      Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/05/20 alle ore 12:38:26