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    1. Medinsky, MA; Bond, JA
      Sites and mechanisms for uptake of gases and vapors in the respiratory tract

      TOXICOLOGY
    2. Bird, MG; Rice, JM; Bond, JA
      Evaluation of 1,3-butadiene, isoprene and chloroprene health risks

      CHEMICO-BIOLOGICAL INTERACTIONS
    3. Bond, JA; Medinsky, MA
      Insights into the toxicokinetics and toxicodynamics of 1,3-butadiene

      CHEMICO-BIOLOGICAL INTERACTIONS
    4. Guy, M; Moorghen, M; Bond, JA; Collard, TJ; Paraskeva, C; Williams, AC
      Transcriptional down-regulation of the retinoblastoma protein is associated with differentiation and apoptosis in human colorectal epithelial cells

      BRITISH JOURNAL OF CANCER
    5. Webley, K; Bond, JA; Jones, CJ; Blaydes, JP; Craig, A; Hupp, T; Wynford-Thomas, D
      Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage

      MOLECULAR AND CELLULAR BIOLOGY
    6. Jones, CJ; Kipling, D; Morris, M; Hepburn, P; Skinner, J; Bounacer, A; Wyllie, FS; Ivan, M; Bartek, J; Wynford-Thomas, D; Bond, JA
      Evidence for a telomere-independent "clock" limiting RAS oncogene-driven proliferation of human thyroid epithelial cells

      MOLECULAR AND CELLULAR BIOLOGY
    7. Bond, JA
      Untitled

      CHEMICO-BIOLOGICAL INTERACTIONS
    8. Medinsky, MA; Wolf, DC; Cattley, RC; Wong, B; Janszen, DB; Farris, GM; Wright, GA; Bond, JA
      Effects of a thirteen-week inhalation exposure to ethyl tertiary butyl ether on Fischer-344 rats and CD-1 mice

      TOXICOLOGICAL SCIENCES
    9. Richardson, KA; Peters, MMCG; Wong, BA; Megens, RHJJJ; van Elburg, PA; Booth, ED; Boogaard, PJ; Bond, JA; Medinsky, MA; Watson, WP; van Sittert, NJ
      Quantitative and qualitative differences in the metabolism of C-14-1,3-butadiene in rats and mice: Relevance to cancer susceptibility

      TOXICOLOGICAL SCIENCES
    10. Bond, JA; Webley, K; Wyllie, FS; Jones, CJ; Craig, A; Hupp, T; Wynford-Thomas, D
      p53-dependent growth arrest and altered p53-immunoreactivity following metabolic labelling with P-32 ortho-phosphate in human fibroblasts

      ONCOGENE
    11. Bond, JA; Haughton, MF; Rowson, JM; Smith, PJ; Gire, V; Wynford-Thomas, D; Wyllie, FS
      Control of replicative life span in human cells: Barriers to clonal expansion intermediate between M1 senescence and M2 crisis

      MOLECULAR AND CELLULAR BIOLOGY
    12. SMITH LL; BOND JA; HOLBERT D; HOUMARD JA; ISRAEL RG; MCCAMMON MR; SMITH SS
      DIFFERENTIAL WHITE CELL COUNT AFTER 2 BOUTS OF DOWNHILL RUNNING

      International journal of sports medicine
    13. OSTERMANGOLKAR SM; MOSS O; JAMES A; BRYANT MS; TURNER M; BOND JA
      EPOXYBUTENE-HEMOGLOBIN ADDUCTS IN RATS AND MICE - DOSE-RESPONSE FOR FORMATION AND PERSISTENCE DURING AND FOLLOWING LONG-TERM LOW-LEVEL EXPOSURE TO BUTADIENE

      Toxicology and applied pharmacology
    14. Medinsky, MA; Bond, JA
      Untitled

      TOXICOLOGY AND APPLIED PHARMACOLOGY
    15. HAM J; WEBSTER J; BOND JA; JASANI B; LEWIS MD; HEPBURN PJ; DAVIES JS; LEWIS BM; THOMAS DW; SCANLON MF
      IMMORTALIZED HUMAN PITUITARY-CELLS EXPRESS GLYCOPROTEIN ALPHA-SUBUNITAND THYROTROPIN-BETA (TSH-BETA)

      The Journal of clinical endocrinology and metabolism
    16. BOND JA; LEAVENS TL; SEATON MJ; MEDINSKY MA
      PREDICTING THE TOXICITY OF CHEMICAL-MIXTURES

      Chemtech
    17. HALLJACKSON CA; JONES T; ECCLES NG; DAWSON TP; BOND JA; GESCHER A; WYNFORDTHOMAS D
      INDUCTION OF CELL-DEATH BY STIMULATION OF PROTEIN-KINASE-C IN HUMAN EPITHELIAL-CELLS EXPRESSING A MUTANT RAS ONCOGENE - A POTENTIAL THERAPEUTIC TARGET

      British Journal of Cancer
    18. FISCHER AH; BOND JA; TAYSAVANG P; BATTLES OE; WYNFORDTHOMAS D
      PAPILLARY THYROID-CARCINOMA ONCOGENE (RET PTC) ALTERS THE NUCLEAR-ENVELOPE AND CHROMATIN STRUCTURE/

      The American journal of pathology
    19. LACY MK; SWARTZ MA; EIDEM LA; BOND JA
      DEVELOPMENT OF A PATIENT-FOCUSED, INTERDISCIPLINARY ANTIMICROBIAL MANAGEMENT PROGRAM INVOLVING STAFF PHARMACISTS

      American journal of health-system pharmacy
    20. HIMMELSTEIN MW; ACQUAVELLA JF; RECIO L; MEDINSKY MA; BOND JA
      TOXICOLOGY AND EPIDEMIOLOGY OF 1,3-BUTADIENE

      Critical reviews in toxicology
    21. IVAN M; BOND JA; PRAT M; COMOGLIO PM; WYNFORDTHOMAS D
      ACTIVATED RAS AND RET ONCOGENES INDUCE OVER-EXPRESSION OF C-MET (HEPATOCYTE GROWTH-FACTOR RECEPTOR) IN HUMAN THYROID EPITHELIAL-CELLS

      Oncogene
    22. LEAVENS TL; FARRIS GM; JAMES RA; SHAH R; WONG VA; MARSHALL MW; BOND JA
      GENOTOXICITY AND CYTOTOXICITY IN MALE B6C3F1 MICE FOLLOWING EXPOSURE TO MIXTURES OF 1,3-BUTADIENE AND STYRENE

      Environmental and molecular mutagenesis
    23. BOND JA; BRADLEY BP
      RESISTANCE TO MALATHION IN HEAT-SHOCKED DAPHNIA-MAGNA

      Environmental toxicology and chemistry
    24. DORMAN DC; STRUVE MF; WONG BA; MORGAN KT; JANSZEN DB; GROSS EB; BOND JA
      NEUROTOXICOLOGICAL EVALUATION OF ETHYL TERTIARY-BUTYL ETHER FOLLOWINGSUBCHRONIC (90-DAY) INHALATION IN THE FISCHER-344 RAT

      Journal of applied toxicology
    25. SWEENEY LM; SCHLOSSER PM; MEDINSKY MA; BOND JA
      PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING OF 1,3-BUTADIENE, 1,2-EPOXY-3-BUTENE, AND 1,2-3,4-DIEPOXYBUTANE TOXICOKINETICS IN MICE AND RATS

      Carcinogenesis
    26. PASTINO GM; ASGHARIAN B; ROBERTS K; MEDINSKY MA; BOND JA
      A COMPARISON OF PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL PREDICTIONS AND EXPERIMENTAL-DATA FOR INHALED ETHANOL IN MALE AND FEMALE B6C3F(1) MICE, F344 RATS, AND HUMANS

      Toxicology and applied pharmacology
    27. IVAN M; LUDGATE M; GIRE V; BOND JA; WYNFORDTHOMAS D
      AN AMPHOTROPIC RETROVIRAL VECTOR EXPRESSING A MUTANT GSP ONCOGENE - EFFECTS ON HUMAN THYROID-CELLS IN-VITRO

      The Journal of clinical endocrinology and metabolism
    28. VALENTINE JL; BOOGAARD PJ; SWEENEY LM; TURNER MJ; BOND JA; MEDINSKY MA
      DISPOSITION OF BUTADIENE EPOXIDES IN SPRAGUE-DAWLEY RATS

      Chemico-biological interactions
    29. WYLLIE FS; HAUGHTON MF; BOND JA; ROWSON JM; JONES CJ; WYNFORDTHOMAS D
      S-PHASE CELL-CYCLE ARREST FOLLOWING DNA-DAMAGE IS INDEPENDENT OF THE P53 P21(WAF1) SIGNALING PATHWAY/

      Oncogene
    30. LEAVENS TL; MOSS OR; BOND JA
      DYNAMIC INHALATION SYSTEM FOR INDIVIDUAL WHOLE-BODY EXPOSURE OF MICE TO VOLATILE ORGANIC-CHEMICALS

      Inhalation toxicology
    31. BOND JA; HIMMELSTEIN MW; MEDINSKY MA
      THE USE OF TOXICOLOGIC DATA IN MECHANISTIC RISK ASSESSMENT - 1,3-BUTADIENE AS A CASE-STUDY

      International archives of occupational and environmental health
    32. BOND JA; HIMMELSTEIN MW; SEATON M; BOOGAARD P; MEDINSKY MA
      METABOLISM OF BUTADIENE BY MICE, RATS, AND HUMANS - A COMPARISON OF PHYSIOLOGICALLY-BASED TOXICOKINETIC MODEL PREDICTIONS AND EXPERIMENTAL-DATA

      Toxicology
    33. RECIO L; SISK S; MEYER K; PLUTA L; BOND JA
      MUTAGENICITY AND MUTATIONAL SPECTRA OF 1,3-BUTADIENE IN THE BONE-MARROW OF B6C3F1 LACI TRANSGENIC MICE

      Toxicology
    34. BOOGAARD PJ; SUMNER SCJ; TURNER MJ; BOND JA
      HEPATIC AND PULMONARY GLUTATHIONE CONJUGATION OF 1,2-3,4-DIEPOXYBUTANE IN HUMAN, RAT, AND MOUSE IN-VITRO

      Toxicology
    35. HIMMELSTEIN MW; TURNER MJ; ASGHARIAN B; BOND JA
      METABOLISM OF 1,3-BUTADIENE - INHALATION PHARMACOKINETICS AND TISSUE DOSIMETRY OF BUTADIENE EPOXIDES IN RATS AND MICE

      Toxicology
    36. LEAVENS TL; BOND JA
      PHARMACOKINETIC MODEL DESCRIBING THE DISPOSITION OF BUTADIENE AND STYRENE IN MICE

      Toxicology
    37. SEATON MJ; PLOPPER CG; BOND JA
      1,3-BUTADIENE METABOLISM BY LUNG AIRWAYS ISOLATED FROM MICE AND RATS

      Toxicology
    38. OSTERMANGOLKAR S; BOND JA
      BIOMONITORING OF 1,3-BUTADIENE AND RELATED-COMPOUNDS

      Environmental health perspectives
    39. BOOGAARD PJ; BOND JA
      THE ROLE OF HYDROLYSIS IN THE DETOXIFICATION OF 1,2 3,4-DIEPOXYBUTANEBY HUMAN, RAT, AND MOUSE-LIVER AND LUNG IN-VITRO/

      Toxicology and applied pharmacology
    40. LEAVENS TL; MOSS OR; TURNER MJ; JANSZEN DB; BOND JA
      METABOLIC INTERACTIONS OF 1,3-BUTADIENE AND STYRENE IN MALE B6C3F1 MICE

      Toxicology and applied pharmacology
    41. BOOGAARD PJ; SUMNER SCJ; BOND JA
      GLUTATHIONE CONJUGATION OF 1,2-3,4-DIEPOXYBUTANE IN HUMAN LIVER AND RAT AND MOUSE-LIVER AND LUNG IN-VITRO

      Toxicology and applied pharmacology
    42. BOND JA; NESS GO; ROWSON J; IVAN M; WHITE D; WYNFORDTHOMAS D
      SPONTANEOUS DEDIFFERENTIATION CORRELATES WITH EXTENDED LIFE-SPAN IN TRANSFORMED THYROID EPITHELIAL-CELLS - AN EPIGENETIC MECHANISM OF TUMORPROGRESSION

      International journal of cancer
    43. PENMETSA KV; SHEA D; LEIDY RB; BOND JA
      ANALYSIS OF BENZO[A]PYRENE-DNA ADDUCTS BY CAPILLARY ELECTROPHORESIS WITH LASER-INDUCED FLUORESCENCE DETECTION

      HRC. Journal of high resolution chromatography
    44. WYNFORDTHOMAS D; BOND JA; WYLLIE FS; JONES CJ
      DOES TELOMERE SHORTENING DRIVE SELECTION FOR P53 MUTATION IN HUMAN CANCER

      Molecular carcinogenesis
    45. BOND JA; MEDINSKY MA
      HEALTH RISK ASSESSMENT OF CHEMICAL-MIXTURES FROM A RESEARCH PERSPECTIVE

      Toxicology letters
    46. ROSA LFBPC; CURI R; BOND JA; NEWSHOLME P; NEWSHOLME EA
      PROPIONATE MODIFIES LIPID BIOSYNTHESIS IN RAT PERITONEAL-MACROPHAGES

      General pharmacology
    47. BOND JA; RECIO L; ANDJELKOVICH D
      EPIDEMIOLOGIC AND MECHANISTIC DATA SUGGEST THAT 1,3-BUTADIENE WILL NOT BE CARCINOGENIC TO HUMANS AT EXPOSURES LIKELY TO BE ENCOUNTERED IN THE ENVIRONMENT OR WORKPLACE

      Carcinogenesis
    48. SEATON MJ; FOLLANSBEE MH; BOND JA
      OXIDATION OF 1,2-EPOXY-3-BUTENE TO 1,2-3,4-DIEPOXYBUTANE BY CDNA-EXPRESSED HUMAN CYTOCHROMES P450 2E1 AND 3A4 AND HUMAN, MOUSE AND RAT-LIVER MICROSOMES

      Carcinogenesis
    49. BOND JA; BRADLEY BP
      HEAT-SHOCK REDUCES THE TOXICITY OF MALATHION IN DAPHNIA-MAGNA

      Marine environmental research
    50. HIMMELSTEIN MW; ASGHARIAN B; BOND JA
      HIGH-CONCENTRATIONS OF BUTADIENE EPOXIDES IN LIVERS AND LUNGS OF MICECOMPARED TO RATS EXPOSED TO 1,3-BUTADIENE

      Toxicology and applied pharmacology
    51. BOND JA; BLAYDES JP; ROWSON J; HAUGHTON MF; SMITH JR; WYNFORDTHOMAS D; WYLLIE FS
      MUTANT P53 RESCUES HUMAN-DIPLOID CELLS FROM SENESCENCE WITHOUT INHIBITING THE INDUCTION OF SDI1 WAF1/

      Cancer research
    52. BOND JA; WYLLIE FS; WYNFORDTHOMAS D
      ESCAPE FROM SENESCENCE IN HUMAN-DIPLOID FIBROBLASTS INDUCED DIRECTLY BY MUTANT P53

      Oncogene
    53. BOND JA; WYLLIE FS; ROWSON J; RADULESCU A; WYNFORDTHOMAS D
      IN-VITRO RECONSTRUCTION OF TUMOR INITIATION IN A HUMAN EPITHELIUM

      Oncogene
    54. BOND JA; DORSEY JF; BROOKE M; MAGILL J; TABLER J
      FAST SOLUTION OF NONLINEAR EQUATIONS USING PARALLEL ANALOG HARDWARE

      Analog integrated circuits and signal processing
    55. BRADLEY BP; GONZALEZ CM; BOND JA; TEPPER BE
      COMPLEX MIXTURE ANALYSIS USING PROTEIN EXPRESSION AS A QUALITATIVE AND QUANTITATIVE TOOL

      Environmental toxicology and chemistry
    56. CURI R; COSTAROSA LFBP; YANO M; BOND JA; DEBITTENCOURT PIH; NEWSHOLME EA
      THE EFFECT OF PROPIONATE ON LIPID-SYNTHESIS IN RAT LYMPHOCYTES

      General pharmacology
    57. SEATON MJ; SCHLOSSER PM; BOND JA; MEDINSKY MA
      BENZENE METABOLISM BY HUMAN LIVER-MICROSOMES IN RELATION TO CYTOCHROME-P450 2E1 ACTIVITY

      Carcinogenesis
    58. HIMMELSTEIN MW; TURNER MJ; ASGHARIAN B; BOND JA
      COMPARISON OF BLOOD-CONCENTRATIONS OF 1,3-BUTADIENE AND BUTADIENE EPOXIDES IN MICE AND RATS EXPOSED TO 1,3-BUTADIENE BY INHALATION

      Carcinogenesis
    59. MEDINSKY MA; LEAVENS TL; CSANADY GA; GARGAS ML; BOND JA
      IN-VIVO METABOLISM OF BUTADIENE BY MICE AND RATS - A COMPARISON OF PHYSIOLOGICAL MODEL PREDICTIONS AND EXPERIMENTAL-DATA

      Carcinogenesis
    60. SISK SC; PLUTA LJ; BOND JA; RECIO L
      MOLECULAR ANALYSIS OF LACI MUTANTS FROM BONE-MARROW OF B6C3F1 TRANSGENIC MICE FOLLOWING INHALATION EXPOSURE TO 1,3-BUTADIENE

      Carcinogenesis
    61. BOND JA; CSANADY GA; GARGAS ML; GUENGERICH FP; LEAVENS T; MEDINSKY MA; RECIO L
      1,3-BUTADIENE - LINKING METABOLISM, DOSIMETRY, AND MUTATION-INDUCTION

      Environmental health perspectives
    62. MEDINSKY MA; SCHLOSSER PM; BOND JA
      CRITICAL ISSUES IN BENZENE TOXICITY AND METABOLISM - THE EFFECT OF INTERACTIONS WITH OTHER ORGANIC-CHEMICALS ON RISK ASSESSMENT

      Environmental health perspectives
    63. DORMAN DC; MOSS OR; FARRIS GM; JANSZEN D; BOND JA; MEDINSKY MA
      PHARMACOKINETICS OF INHALED [C-14] METHANOL AND METHANOL-DERIVED [C-14] FORMATE IN NORMAL AND FOLATE-DEFICIENT CYNOMOLGUS MONKEYS

      Toxicology and applied pharmacology
    64. DORMAN DC; MOSS OR; FARRIS GM; JANSZEN D; BOND JA; MEDINSKY MA
      PHARMACOKINETICS OF INHALED [C-14] METHANOL AND METHANOL-DERIVED [C-14] FORMATE IN NORMAL AND FOLATE-DEFICIENT CYNOMOLGUS MONKEYS

      Toxicology and applied pharmacology
    65. RUGGIERI P; SIM FH; BOND JA; UNNI KK
      MALIGNANCIES IN FIBROUS DYSPLASIA

      Cancer
    66. BOND JA
      METABOLISM AND ELIMINATION OF INHALED DRUGS AND AIRBORNE CHEMICALS FROM THE LUNGS

      Pharmacology & toxicology
    67. CURI R; BOND JA; CALDER PC; NEWSHOLME EA
      PROPIONATE REGULATES LYMPHOCYTE-PROLIFERATION AND METABOLISM

      General pharmacology
    68. BOND JA; GONZALEZ CRM; BRADLEY BP
      AGE-DEPENDENT EXPRESSION OF PROTEINS IN THE CLADOCERAN DAPHNIA-MAGNA UNDER NORMAL AND HEAT-STRESS CONDITIONS

      Comparative biochemistry and physiology. B. Comparative biochemistry
    69. BOND JA; WYLLIE FS; IVAN M; DAWSON T; WYNFORDTHOMAS D
      A VARIANT EPITHELIAL SUBPOPULATION IN NORMAL THYROID WITH HIGH PROLIFERATIVE CAPACITY INVITRO

      Molecular and cellular endocrinology
    70. SCHLOSSER PM; BOND JA; MEDINSKY MA
      BENZENE AND PHENOL METABOLISM BY MOUSE AND RAT-LIVER MICROSOMES

      Carcinogenesis


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Documento generato il 22/01/21 alle ore 12:08:53