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Titolo:
OCCUPATIONAL EXPOSURES AND HEMATOLOGICAL ABNORMALITIES AMONG ORDNANCEFACTORY-WORKERS - A CASE-CONTROL STUDY
Autore:
WEST RR; STAFFORD DA;
Indirizzi:
UNIV WALES COLL CARDIFF,COLL MED,HEATH PK CARDIFF S GLAM WALES
Titolo Testata:
Leukemia research
fascicolo: 7, volume: 21, anno: 1997,
pagine: 675 - 680
SICI:
0145-2126(1997)21:7<675:OEAHAA>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
MYELODYSPLASTIC SYNDROMES; BENZENE; LEUKEMIA;
Keywords:
OCCUPATIONAL EXPOSURE; HEMATOLOGICAL ABNORMALITIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
R.R. West e D.A. Stafford, "OCCUPATIONAL EXPOSURES AND HEMATOLOGICAL ABNORMALITIES AMONG ORDNANCEFACTORY-WORKERS - A CASE-CONTROL STUDY", Leukemia research, 21(7), 1997, pp. 675-680

Abstract

The lifetime exposures to an extensive list of chemical and other potentially toxic hazards were estimated for all available employees at an ordnance factory by questionnaire-based interview. Exposure histories of 32 (of 33) previously diagnosed as haematologically abnormal (cases) were compared with 322 (of 345) normals (controls). Among 'ordnance factory chemicals', modestly increased odds ratios were observed formen for acetic anhydride (2.8), stearic acid (2.8), and possibly for resorcinol (2.9), TNT (2.4) and hydroxy terminated polybutadene (HTPB)(2.4). Increased odds ratios were also observed in exposures not directly related to ordnance manufacture, including mineral acids, weldingfumes, exhaust gases and insecticides. While, small numbers in the case group limit the statistical significance of reported odds ratios, one should be cautious about committing a type II error. These findingsmay partly explain the previously reported unusual prevalence of haematological abnormalities within the factory. (C) 1997 Elsevier ScienceLtd.

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Documento generato il 03/07/20 alle ore 16:34:57