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Titolo:
COMBAT VETERANS WITH POSTTRAUMATIC-STRESS-DISORDER EXHIBIT DECREASED HABITUATION OF THE P1 MIDLATENCY AUDITORY-EVOKED POTENTIAL
Autore:
GILLETTE GM; SKINNER RD; RASCO LM; FIELSTEIN EM; DAVIS DH; PAWELAK JE; FREEMAN TW; KARSON CN; BOOP FA; GARCIARILL E;
Indirizzi:
VET AFFAIRS MED CTR,PSYCHIAT SERV,1310 24TH AVE S NASHVILLE TN 37212 JOHN L MCCLELLAN MEM VET ADM MED CTR,EUGENE J TOWBIN HLTH CARE CTR,N LITTLE ROCK DIV N LITTLE ROCK AR 00000 UNIV ARKANSAS MED SCI,DEPT ANAT LITTLE ROCK AR 72205 UNIV ARKANSAS MED SCI,DEPT PSYCHIAT LITTLE ROCK AR 72205 UNIV ARKANSAS MED SCI,DEPT NEUROSURG LITTLE ROCK AR 72205 VANDERBILT UNIV,MED CTR,DEPT PSYCHIAT NASHVILLE TN 00000
Titolo Testata:
Life sciences
fascicolo: 14, volume: 61, anno: 1997,
pagine: 1421 - 1434
SICI:
0024-3205(1997)61:14<1421:CVWPED>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
SENSORY GATING DEFICITS; NEUROPHYSIOLOGICAL EVIDENCE; PEDUNCULOPONTINE NUCLEUS; RESPONSES; SCHIZOPHRENIA; SLEEP; P50; SUPPRESSION; MECHANISMS; DEFECT;
Keywords:
POSTTRAUMATIC STRESS DISORDER; MIDLATENCY AUDITORY EVOKED POTENTIAL; PEDUNCULOPONTINE NUCLEUS; COMBAT VETERANS; SLEEP DISTURBANCES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
55
Recensione:
Indirizzi per estratti:
Citazione:
G.M. Gillette et al., "COMBAT VETERANS WITH POSTTRAUMATIC-STRESS-DISORDER EXHIBIT DECREASED HABITUATION OF THE P1 MIDLATENCY AUDITORY-EVOKED POTENTIAL", Life sciences, 61(14), 1997, pp. 1421-1434

Abstract

The current study used a paired stimulus paradigm to investigate the P1 midlatency auditory evoked potential in Vietnam combat veterans with posttraumatic stress disorder (PTSD) and three comparison groups: alcohol dependents, combat-exposed normals, and combat-unexposed normals. Compared to each comparison group, PTSD subjects exhibited significantly diminished habituation of the P1 potential. P1 potential habituation within the PTSD group, correlated significantly with intensity of PTSD reexperiencing symptoms, such as trauma-related nightmares and flashbacks. These findings are discussed as consistent with a sensory gating defect at the brainstem level in PTSD, and are further discussed in the context of other psychophysiological measures in PTSD and of P1potential findings in psychiatric disorders other than PTSD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/01/20 alle ore 19:07:22