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Titolo:
THE SMALLER SIZE OF THE CELIAC ICEBERG IN ADULTS
Autore:
CORAZZA GR; ANDREANI ML; BIAGI F; CORRAO G; PRETOLANI S; GIULIANELLI G; GHIRONZI G; GASBARRINI G;
Indirizzi:
UNIV AQUILA,DIPARTIMENTO MED INTERNA,VIA S SISTO 22-E I-67100 LAQUILAITALY UNIV MILAN,MARCELLO BOLDRINI INST STAT & MATH SCI MILAN ITALY CATHOLIC UNIV ROME,MED CLIN ROME ITALY INST SOCIAL SECUR,DIV GEN MED SAN MARINO SAN MARINO
Titolo Testata:
Scandinavian journal of gastroenterology
fascicolo: 9, volume: 32, anno: 1997,
pagine: 917 - 919
SICI:
0036-5521(1997)32:9<917:TSSOTC>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
SELECTIVE IGA DEFICIENCY; CELIAC-DISEASE; ANTIGLIADIN ANTIBODIES; HIGH PREVALENCE;
Keywords:
ANTIENDOMYSIAL ANTIBODIES; CELIAC DISEASE; CELIAC DISEASE, EPIDEMIOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
G.R. Corazza et al., "THE SMALLER SIZE OF THE CELIAC ICEBERG IN ADULTS", Scandinavian journal of gastroenterology, 32(9), 1997, pp. 917-919

Abstract

Background: Since it has been ascertained that the prevalence of coeliac disease in the general paediatric population is 3.3 per 1000, we decided to evaluate this prevalence in the general adult population. Methods: Two thousand two hundred and thirty-seven adult subjects aged 20-87 years, representative of a population with sociodemographic characteristics typical of Western European countries with regard to sex and age, were studied. In all serum IgA antiendomysial antibodies (EMA) were searched for, and all patients who turned out to be positive underwent intestinal biopsy. Results: Four symptomless subjects aged between 20 and 39 years proved positive at the IgA EMA screening. The intestinal biopsy confirmed coeliac disease in all of them. The prevalence in our study group was, therefore, 1.8 per 1000. Conclusions: This study shows that the size of the submerged part of the 'coeliac iceberg' is perhaps smaller in the adult population and suggests a linear trendtowards a lower coeliac disease prevalence as age increases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 13:16:07