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Titolo:
ANTIENDOTHELIAL CELL ANTIBODY, THROMBOMODULIN, AND VON-WILLEBRAND-FACTOR IN IDIOPATHIC INFLAMMATORY MYOPATHIES
Autore:
SALOJIN KV; BORDRON A; NASSONOV EL; SHTUTMAN VZ; GUSEVA NG; BARANOV AA; TARGOFF IN; YOUINOU P;
Indirizzi:
BREST UNIV,MED SCH HOSP,IMMUNOL LAB,BP 824 F-29609 BREST FRANCE BREST UNIV,MED SCH HOSP,IMMUNOL LAB F-29609 BREST FRANCE CARDIOL RES CTR MOSCOW 121552 RUSSIA UNIV OKLAHOMA,MED RES FDN OKLAHOMA CITY OK 00000
Titolo Testata:
Clinical and diagnostic laboratory immunology
fascicolo: 5, volume: 4, anno: 1997,
pagine: 519 - 521
SICI:
1071-412X(1997)4:5<519:ACATAV>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
VIII-RELATED ANTIGEN; DERMATOMYOSITIS; AUTOANTIBODIES; POLYMYOSITIS; COMPLEMENT; DISEASE; VASCULITIS; MYOSITIS; FORMS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
K.V. Salojin et al., "ANTIENDOTHELIAL CELL ANTIBODY, THROMBOMODULIN, AND VON-WILLEBRAND-FACTOR IN IDIOPATHIC INFLAMMATORY MYOPATHIES", Clinical and diagnostic laboratory immunology, 4(5), 1997, pp. 519-521

Abstract

Sera from 19 patients,vith idiopathic inflammatory myopathy (IIM) were examined for the presence of anti-endothelial cell antibodies (AECA)by an immunoglobulin G-specific cellular enzyme-linked immunosorbent assay, The mean binding index of AECA was found to be 37.7% +/- 26.5% for the patients, compared with a mean of 7.2% +/- 2.7% for normal controls (P < 0.04). Levels of thrombomodulin, von Willebrand factor antigen, and serum creatine kinase were also shown to be augmented. Interestingly, positive correlations between AECA on the one hand and Raynaud's phenomenon and interstitial lung disease on the other were demonstrated. Given that the pathogenesis of IIM remains uncertain, these findings may be of importance.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 23:39:48