Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
UPDATE ON ACTIVE SPECIFIC IMMUNOTHERAPY WITH MELANOMA VACCINES
Autore:
CONFORTI AM; OLLILA DW; KELLEY MC; GAMMON G; MORTON DL;
Indirizzi:
ST JOHNS HLTH CTR,JOHN WAYNE CANC INST,ROY E COATS RES LABS,2200 SANTA MONICA BLVD SANTA MONICA CA 90404 ST JOHNS HLTH CTR,JOHN WAYNE CANC INST,ROY E COATS RES LABS SANTA MONICA CA 90404 ST JOHNS HLTH CTR,JOHN WAYNE CANC INST,SONYA VALLEY GHIDOSSI VACCINE LAB SANTA MONICA CA 90404
Titolo Testata:
Journal of surgical oncology
fascicolo: 1, volume: 66, anno: 1997,
pagine: 55 - 64
SICI:
0022-4790(1997)66:1<55:UOASIW>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTITUMOR IMMUNE-RESPONSES; CYTOLYTIC T-LYMPHOCYTES; TUMOR-INFILTRATING LYMPHOCYTES; PURIFIED GM2 GANGLIOSIDE; STAGE-III MELANOMA; MALIGNANT-MELANOMA; METASTATIC MELANOMA; DENDRITIC CELLS; MONOCLONAL-ANTIBODY; CANCER VACCINE;
Keywords:
IMMUNOMODULATION; ANTIGEN; HUMORAL/CELLULAR IMMUNITY; AUTOLOGOUS/ALLOGENEIC VACCINES;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
91
Recensione:
Indirizzi per estratti:
Citazione:
A.M. Conforti et al., "UPDATE ON ACTIVE SPECIFIC IMMUNOTHERAPY WITH MELANOMA VACCINES", Journal of surgical oncology, 66(1), 1997, pp. 55-64

Abstract

Although a randomized clinical trial has yet to show a statistically significant improvement in the survival of patients receiving vaccine therapy for malignant melanoma, several studies have shown enhanced survival of patients developing an immune response to a melanoma vaccine. The knowledge and techniques of modern molecular biology and immunology suggest multiple strategies to augment this response. The challenge of immunotherapy research is to determine which combination of approaches leads to a favorable clinical response and how to monitor that response effectively. This review identifies components of a successfulvaccine, discusses new ways to modulate and stimulate the immune system, and summarizes some of the more interesting clinical trials of melanoma vaccine immunotherapy. (C) 1997 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 09:14:43